## Thu Feb 19 06:28:36 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158416_bin.9.fa -m mmseqs --output SRR25158416_bin.9 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158416_bin.9 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158416_k127_1073918_19	1120950.KB892798_gene2194	3.197e-31	123.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4DNWM@85009|Propionibacteriales	201174|Actinobacteria	G	protein probably involved in trehalose biosynthesis	mak	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158416_k127_1073918_17	351607.Acel_0379	1.203e-37	156.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_1073918_1	390989.JOEG01000001_gene5397	2.722e-306	949.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4DBXC@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158416_k127_1073918_9	1306174.JODP01000018_gene4385	1.466e-87	299.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158416_k127_1073918_2	1957.JODX01000005_gene3464	1.646e-300	931.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158416_k127_1073918_14	525904.Tter_2222	1.076e-42	165.0	COG1959@1|root,COG1959@2|Bacteria,2NPZX@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	iscR	-	2.8.1.7	ko:K04487,ko:K13643	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03000,ko03016,ko03029	-	-	-	Rrf2
SRR25158416_k127_1073918_10	469371.Tbis_0920	1.987e-66	230.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4DXV5@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158416_k127_1073918_20	1120950.KB892745_gene2919	2.8e-20	100.0	COG3428@1|root,COG3428@2|Bacteria,2IA1C@201174|Actinobacteria,4DR83@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158416_k127_1073918_5	479435.Kfla_4985	3.078e-142	456.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DMZ6@85009|Propionibacteriales	201174|Actinobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158416_k127_1073918_4	1089455.MOPEL_003_00210	5.307e-192	610.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4F61N@85018|Dermatophilaceae	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA4	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_1073918_13	1229780.BN381_80027	1.537e-52	208.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,3UWVY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158416_k127_1073918_12	1193181.BN10_1170015	6.066e-60	213.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4FGBB@85021|Intrasporangiaceae	201174|Actinobacteria	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158416_k127_1073918_8	469371.Tbis_0915	9.075e-89	312.0	COG2268@1|root,COG2268@2|Bacteria,2I4D8@201174|Actinobacteria,4EDNE@85010|Pseudonocardiales	201174|Actinobacteria	S	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158416_k127_1073918_18	1120950.KB892745_gene2909	1.937e-32	139.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,4DS23@85009|Propionibacteriales	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1073918_3	479435.Kfla_5009	4.144e-207	658.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4DMY4@85009|Propionibacteriales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158416_k127_1073918_7	68260.JOAY01000002_gene5221	9.647e-116	378.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158416_k127_1073918_6	479433.Caci_5112	8.164e-129	416.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
SRR25158416_k127_1073918_15	408672.NBCG_03855	1.444e-39	150.0	COG0346@1|root,COG0346@2|Bacteria,2IS2C@201174|Actinobacteria,4DS9N@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1073918_16	408672.NBCG_03854	2.964e-38	147.0	2DP8C@1|root,330ZY@2|Bacteria,2I38N@201174|Actinobacteria,4DS3W@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR25158416_k127_1073918_0	58123.JOFJ01000014_gene5098	0.0	1463.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158416_k127_1073918_11	1304865.JAGF01000001_gene739	4.005e-66	246.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_1076819_10	1389489.O159_20470	6.938e-53	190.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4FP8Q@85023|Microbacteriaceae	201174|Actinobacteria	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158416_k127_1076819_5	1151119.KB895501_gene2885	4.057e-118	387.0	COG1082@1|root,COG1082@2|Bacteria,2I2WE@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158416_k127_1076819_0	1122609.AUGT01000010_gene3791	4.2e-175	562.0	COG1653@1|root,COG1653@2|Bacteria,2H0FP@201174|Actinobacteria,4DTIM@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158416_k127_1076819_3	1122609.AUGT01000010_gene3792	4.487e-123	404.0	COG1175@1|root,COG1175@2|Bacteria,2GJ70@201174|Actinobacteria,4DTVH@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_1076819_4	1122609.AUGT01000010_gene3793	6.775e-120	411.0	COG0395@1|root,COG0395@2|Bacteria,2GJPF@201174|Actinobacteria,4DT9Z@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_1076819_2	1206741.BAFX01000147_gene2778	1.563e-153	501.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4FUMN@85025|Nocardiaceae	201174|Actinobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
SRR25158416_k127_1076819_8	1123024.AUII01000028_gene2518	1.326e-64	229.0	COG0406@1|root,COG0406@2|Bacteria,2HRP2@201174|Actinobacteria,4EAZ6@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158416_k127_1076819_6	33876.JNXY01000021_gene4782	3.132e-117	394.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_1076819_9	649831.L083_7332	1.115e-61	226.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	waaD	-	2.4.1.56	ko:K00713,ko:K03280	ko00540,ko01100,map00540,map01100	M00080	R01996	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4,GT9	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_1076819_12	33876.JNXY01000021_gene4781	8.532e-20	93.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158416_k127_1076819_7	33876.JNXY01000021_gene4780	2.287e-102	343.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4DBD5@85008|Micromonosporales	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
SRR25158416_k127_1076819_1	710686.Mycsm_01466	5.522e-164	528.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,2I3VK@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2,RibD_C
SRR25158416_k127_1076819_13	1223543.GP2_003_01050	4.866e-19	91.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_1076819_11	446469.Sked_19220	1.164e-48	188.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria	201174|Actinobacteria	D	Ribonuclease bn	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158416_k127_1076819_14	326424.FRAAL5813	8.8e-06	57.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_1083997_2	1869.MB27_15940	6.403e-84	284.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4DGXT@85008|Micromonosporales	201174|Actinobacteria	S	Survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158416_k127_1083997_0	263358.VAB18032_27836	1.127e-119	393.0	COG1105@1|root,COG1105@2|Bacteria,2HTUE@201174|Actinobacteria,4D8IF@85008|Micromonosporales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158416_k127_1083997_1	110319.CF8_2544	5.829e-93	317.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DQY1@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158416_k127_1084937_1	196162.Noca_2404	1.442e-186	590.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4DP5Q@85009|Propionibacteriales	201174|Actinobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158416_k127_1084937_8	1146883.BLASA_2340	6.825e-26	111.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4ET7N@85013|Frankiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRR25158416_k127_1084937_9	1906.SFRA_29345	1.769e-11	73.0	2EGGE@1|root,33A8E@2|Bacteria,2IKUG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1084937_0	1123251.ATWM01000002_gene464	0.0	1131.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4FE6Z@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158416_k127_1084937_6	1120950.KB892708_gene4297	3.043e-52	189.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4DR7E@85009|Propionibacteriales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158416_k127_1084937_4	1111131.HMPREF1255_1561	6.778e-78	274.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4DN3K@85009|Propionibacteriales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158416_k127_1084937_7	1120950.KB892708_gene4301	4.934e-37	149.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4DRTI@85009|Propionibacteriales	201174|Actinobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158416_k127_1084937_2	1122138.AQUZ01000011_gene5034	2.051e-185	587.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4DPU4@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR25158416_k127_1084937_5	471852.Tcur_2952	6.679e-56	204.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria,4EJ4W@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158416_k127_1084937_3	479433.Caci_2390	1.192e-118	389.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158416_k127_1091905_4	1385519.N801_04640	1.045e-233	730.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4FE57@85021|Intrasporangiaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158416_k127_1091905_0	1137269.AZWL01000023_gene1188	0.0	1043.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158416_k127_1091905_9	479435.Kfla_1337	1.529e-130	428.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DPU6@85009|Propionibacteriales	201174|Actinobacteria	C	Succinate dehydrogenase fumarate reductase	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
SRR25158416_k127_1091905_1	1122138.AQUZ01000069_gene2245	1.96e-321	991.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DPTE@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158416_k127_1091905_13	1122933.JNIY01000003_gene850	1.502e-65	227.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,4F188@85016|Cellulomonadaceae	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158416_k127_1091905_14	479435.Kfla_1340	1.013e-57	205.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria	201174|Actinobacteria	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158416_k127_1091905_16	1306990.BARG01000035_gene4209	4.138e-19	96.0	2ECD9@1|root,336BH@2|Bacteria,2I6UD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1091905_2	1120950.KB892760_gene5779	5.407e-269	836.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4DWYX@85009|Propionibacteriales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	bhbA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158416_k127_1091905_10	196162.Noca_0545	1.11e-129	421.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4DUSI@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158416_k127_1091905_12	196162.Noca_0544	1.501e-105	353.0	COG0274@1|root,COG0274@2|Bacteria,2IARI@201174|Actinobacteria,4DUNX@85009|Propionibacteriales	201174|Actinobacteria	F	DeoC/LacD family aldolase	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158416_k127_1091905_6	196162.Noca_0542	5.394e-172	543.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4DT4I@85009|Propionibacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158416_k127_1091905_7	196162.Noca_3541	1.574e-164	523.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4DPNT@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	bmpA	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158416_k127_1091905_3	196162.Noca_3540	1.147e-262	817.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4DN52@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter, ATP-binding protein	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158416_k127_1091905_8	196162.Noca_3539	2.985e-161	514.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,4DNZT@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158416_k127_1091905_5	196162.Noca_3538	1.998e-182	580.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4DPWG@85009|Propionibacteriales	201174|Actinobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158416_k127_1091905_15	1386089.N865_02900	1.972e-55	197.0	COG0295@1|root,COG0295@2|Bacteria,2IHP7@201174|Actinobacteria,4FGKS@85021|Intrasporangiaceae	201174|Actinobacteria	F	cytidine deaminase	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158416_k127_1091905_11	743718.Isova_0969	1.24e-112	368.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,4F3VS@85017|Promicromonosporaceae	201174|Actinobacteria	F	Pyrimidine nucleoside phosphorylase C-terminal domain	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158416_k127_1097208_4	1214242.B446_29005	6.013e-06	48.0	COG3576@1|root,COG3576@2|Bacteria,2I2U7@201174|Actinobacteria	201174|Actinobacteria	C	Pfam Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_1097208_1	1120949.KB903295_gene2534	4.27e-24	105.0	29JYD@1|root,306VN@2|Bacteria,2GWXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1097208_2	1298863.AUEP01000007_gene396	2.353e-15	81.0	2DS2T@1|root,33E9A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158416_k127_1097208_5	1229780.BN381_800005	0.0001291	46.0	2EKGQ@1|root,33E6R@2|Bacteria	2|Bacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_1097208_0	1907.SGLAU_06405	1.884e-242	789.0	2EW54@1|root,33PI8@2|Bacteria,2I8RV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SRR25158416_k127_1097208_3	1151061.CAJY01000030_gene1856	1.558e-14	74.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158416_k127_1114423_10	1121946.AUAX01000023_gene4182	2.064e-79	271.0	COG0596@1|root,COG0596@2|Bacteria,2GJ4I@201174|Actinobacteria,4DM56@85008|Micromonosporales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_1114423_9	1122622.ATWJ01000009_gene3042	9.291e-82	287.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4FEBD@85021|Intrasporangiaceae	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158416_k127_1114423_14	479435.Kfla_6323	7.003e-64	226.0	COG1309@1|root,COG1309@2|Bacteria,2GJHD@201174|Actinobacteria,4DQB9@85009|Propionibacteriales	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158416_k127_1114423_5	479435.Kfla_6322	1.472e-171	561.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DP72@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_1114423_11	1179773.BN6_04410	9.399e-69	243.0	COG0572@1|root,COG0572@2|Bacteria,2GMCP@201174|Actinobacteria,4E35R@85010|Pseudonocardiales	201174|Actinobacteria	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SRR25158416_k127_1114423_15	1050202.KB913024_gene2110	7.444e-58	208.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,408JV@622450|Actinopolysporales	201174|Actinobacteria	J	Polypeptide deformylase	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158416_k127_1114423_6	1120950.KB892757_gene6517	3.866e-169	548.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4DNKE@85009|Propionibacteriales	201174|Actinobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158416_k127_1114423_16	1298863.AUEP01000008_gene1328	1.313e-38	157.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4DQUX@85009|Propionibacteriales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158416_k127_1114423_17	1211815.CBYP010000060_gene3073	1.423e-16	85.0	COG3030@1|root,COG3030@2|Bacteria,2HPHE@201174|Actinobacteria,4ETIT@85013|Frankiales	201174|Actinobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
SRR25158416_k127_1114423_8	1449355.JQNR01000005_gene5330	1.853e-100	334.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria	201174|Actinobacteria	H	PFAM Glycosyl transferase family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158416_k127_1114423_7	477641.MODMU_2634	4.047e-130	435.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,4ERH9@85013|Frankiales	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158416_k127_1114423_4	1123322.KB904634_gene2335	1.041e-176	569.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria	201174|Actinobacteria	E	amidohydrolase	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158416_k127_1114423_2	1032480.MLP_13250	1.715e-200	634.0	COG0160@1|root,COG0160@2|Bacteria,2GJNQ@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.36	ko:K03918	ko01100,map01100	-	R00457	RC00006,RC00062	ko00000,ko01000,ko01007	-	-	iNJ661.Rv3290c	Aminotran_3
SRR25158416_k127_1114423_1	68260.JOAY01000019_gene1517	1.109e-251	786.0	COG1012@1|root,COG1012@2|Bacteria,2GT45@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158416_k127_1114423_0	1449069.JMLO01000010_gene409	1.468e-286	906.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4FV1H@85025|Nocardiaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158416_k127_1114423_3	1289387.AUKW01000025_gene2827	4.996e-196	623.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_1114423_18	1089545.KB913037_gene3524	3.831e-15	81.0	2EMTZ@1|root,33FGB@2|Bacteria,2GUCW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158416_k127_1114423_13	105420.BBPO01000025_gene7173	3.413e-66	229.0	COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria,2NI9N@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix ASNC type	lrp_3	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158416_k127_1114423_12	1123321.KB905819_gene5937	3.091e-68	248.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_1114423_21	1036674.A28LD_1649	7.035e-05	49.0	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,1S97H@1236|Gammaproteobacteria,2QGXA@267893|Idiomarinaceae	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
SRR25158416_k127_1114423_19	263358.VAB18032_07420	5.388e-15	78.0	2CKFY@1|root,33NYU@2|Bacteria,2HUZM@201174|Actinobacteria,4DGEC@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_1114423_20	1246448.ANAZ01000014_gene1473	3.711e-07	57.0	COG3378@1|root,COG3378@2|Bacteria,2I37I@201174|Actinobacteria,4EJ64@85012|Streptosporangiales	201174|Actinobacteria	S	Bifunctional DNA primase/polymerase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Prim-Pol
SRR25158416_k127_1118736_6	1122611.KB903941_gene2239	2.452e-90	304.0	COG3217@1|root,COG3217@2|Bacteria,2GPWY@201174|Actinobacteria,4EIZG@85012|Streptosporangiales	201174|Actinobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158416_k127_1118736_10	2002.JOEQ01000030_gene2145	5.328e-79	278.0	COG3173@1|root,COG3173@2|Bacteria,2I1NG@201174|Actinobacteria,4ENVX@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_1118736_12	68170.KL590493_gene6389	1.324e-66	245.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E3IX@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_1118736_8	2074.JNYD01000006_gene1696	1.311e-81	276.0	COG3145@1|root,COG3145@2|Bacteria,2GNBD@201174|Actinobacteria,4E0FZ@85010|Pseudonocardiales	201174|Actinobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRR25158416_k127_1118736_3	1172188.KB911825_gene3603	5.186e-133	433.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria,4FEV1@85021|Intrasporangiaceae	201174|Actinobacteria	S	apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158416_k127_1118736_1	134676.ACPL_506	1.291e-178	577.0	COG1409@1|root,COG1409@2|Bacteria,2GP1M@201174|Actinobacteria,4DBV7@85008|Micromonosporales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158416_k127_1118736_11	1298863.AUEP01000004_gene2088	4.824e-68	238.0	COG3945@1|root,COG3945@2|Bacteria,2INA1@201174|Actinobacteria,4DUJ0@85009|Propionibacteriales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158416_k127_1118736_7	1032480.MLP_00720	5.51e-88	295.0	COG2197@1|root,COG2197@2|Bacteria,2GN29@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_1118736_2	1032480.MLP_00730	3.758e-148	484.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_1118736_14	1032480.MLP_00740	2.421e-33	133.0	COG2197@1|root,COG2197@2|Bacteria,2I5RT@201174|Actinobacteria	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_1118736_5	1032480.MLP_00750	5.433e-123	415.0	COG1638@1|root,COG1638@2|Bacteria,2IN3X@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
SRR25158416_k127_1118736_4	1032480.MLP_00760	1.098e-124	442.0	COG4585@1|root,COG4585@2|Bacteria,2IQ96@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158416_k127_1118736_13	1123320.KB889640_gene4459	2.904e-61	233.0	COG3427@1|root,COG3427@2|Bacteria,2IEYK@201174|Actinobacteria	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158416_k127_1118736_0	1123320.KB889640_gene4458	0.0	1221.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158416_k127_1118736_9	479433.Caci_1872	5.033e-80	271.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.2.5.3,1.5.99.14	ko:K03518,ko:K19186	ko00760,ko01120,map00760,map01120	M00810	R07514,R11168	RC01860,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158416_k127_1118736_15	1380347.JNII01000011_gene1040	3.396e-29	119.0	COG1319@1|root,COG1319@2|Bacteria,2GP37@201174|Actinobacteria,4ESGB@85013|Frankiales	201174|Actinobacteria	C	dehydrogenase, FAD-binding	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158416_k127_1118927_0	1449353.JQMQ01000005_gene2063	2.687e-211	667.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,2NEZ8@228398|Streptacidiphilus	201174|Actinobacteria	J	tRNA synthetases class I (E and Q), catalytic domain	gltX	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iNJ661.Rv2992c	tRNA-synt_1c
SRR25158416_k127_1118927_1	1120950.KB892741_gene2685	5.989e-118	384.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4DPHV@85009|Propionibacteriales	201174|Actinobacteria	Q	Domain of unknown function (DUF2437)	fahA	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158416_k127_1123461_24	656024.FsymDg_1624	2.452e-19	87.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4ERS4@85013|Frankiales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158416_k127_1123461_1	33876.JNXY01000005_gene8798	3.903e-277	865.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4DBBT@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158416_k127_1123461_20	1120936.KB907212_gene4992	9.013e-30	123.0	COG2732@1|root,COG2732@2|Bacteria	2|Bacteria	K	(Barnase) inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
SRR25158416_k127_1123461_15	446462.Amir_0158	4.619e-86	304.0	COG2232@1|root,COG2232@2|Bacteria,2IDDC@201174|Actinobacteria,4DXWM@85010|Pseudonocardiales	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_13	593907.Celgi_1251	1.223e-104	344.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4F0NV@85016|Cellulomonadaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158416_k127_1123461_9	1048339.KB913029_gene4786	3.349e-130	423.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4ERUY@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158416_k127_1123461_18	1121033.AUCF01000004_gene4979	4.262e-57	205.0	COG3554@1|root,COG3554@2|Bacteria,1RJAA@1224|Proteobacteria,2UCI5@28211|Alphaproteobacteria,2JTUB@204441|Rhodospirillales	204441|Rhodospirillales	S	Putative glycolipid-binding	-	-	-	-	-	-	-	-	-	-	-	-	Glycolipid_bind
SRR25158416_k127_1123461_10	1122138.AQUZ01000004_gene1118	1.122e-124	407.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4DPI0@85009|Propionibacteriales	201174|Actinobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158416_k127_1123461_16	1894.JOER01000021_gene4025	9.878e-80	278.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	mntB	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158416_k127_1123461_17	446466.Cfla_2183	1.514e-76	267.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4F23Y@85016|Cellulomonadaceae	201174|Actinobacteria	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158416_k127_1123461_28	1043205.AFYF01000053_gene3084	7.642e-07	61.0	2C98I@1|root,33EGA@2|Bacteria,2GXMN@201174|Actinobacteria,4FHNN@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_22	656024.FsymDg_1631	2.525e-25	114.0	COG2329@1|root,COG2329@2|Bacteria,2GQZB@201174|Actinobacteria,4ETIB@85013|Frankiales	201174|Actinobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_1123461_14	2074.JNYD01000007_gene2100	3.433e-100	340.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4DY5S@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YibE F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158416_k127_1123461_2	35754.JNYJ01000043_gene4536	5.557e-248	772.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4DBAM@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158416_k127_1123461_27	446470.Snas_0386	2.292e-07	57.0	2ENYP@1|root,2ZP5Y@2|Bacteria,2HZ4T@201174|Actinobacteria,4F0BQ@85014|Glycomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_5	479435.Kfla_2480	9.94e-170	540.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DNZA@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158416_k127_1123461_0	351607.Acel_0801	0.0	1303.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4ERQZ@85013|Frankiales	201174|Actinobacteria	G	pyruvate phosphate dikinase, PEP	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158416_k127_1123461_6	266940.Krad_3364	3.681e-167	535.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria	201174|Actinobacteria	F	Deoxyguanosinetriphosphate triphosphohydrolase-like protein	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158416_k127_1123461_7	1123024.AUII01000013_gene447	2.999e-161	516.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4DZ12@85010|Pseudonocardiales	201174|Actinobacteria	S	Reductase C-terminal	fprD	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158416_k127_1123461_3	1120950.KB892739_gene3932	3.935e-229	726.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4DN6K@85009|Propionibacteriales	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158416_k127_1123461_11	1463917.JODC01000006_gene7990	8.932e-124	407.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_1123461_21	1120950.KB892739_gene3921	5.366e-27	116.0	COG0776@1|root,COG0776@2|Bacteria,2GTF6@201174|Actinobacteria,4DS6N@85009|Propionibacteriales	201174|Actinobacteria	L	regulation of translation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_23	1380356.JNIK01000015_gene2665	4.784e-20	92.0	2DRVB@1|root,33D80@2|Bacteria,2GRUJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_4	211114.JOEF01000006_gene2567	7.871e-176	582.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DZY0@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158416_k127_1123461_19	1068978.AMETH_3259	4.24e-44	165.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4E5WF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_8	1120949.KB903304_gene6953	4.283e-160	509.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4D8VN@85008|Micromonosporales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158416_k127_1123461_26	675635.Psed_2025	1.216e-11	71.0	2CCJS@1|root,32RVX@2|Bacteria,2IR2M@201174|Actinobacteria,4E6UM@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_29	345341.KUTG_04729	0.0002196	52.0	2CCJS@1|root,32RVX@2|Bacteria,2IR2M@201174|Actinobacteria,4E4PA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1123461_12	1323361.JPOC01000040_gene4238	2.13e-115	381.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4G001@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_1147557_0	1122138.AQUZ01000012_gene6001	2.528e-146	473.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4DPTR@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158416_k127_1147557_4	1459636.NTE_03221	1.18e-57	211.0	COG0500@1|root,arCOG01783@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158416_k127_1147557_1	1079986.JH164861_gene7150	2.789e-132	441.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_1147557_2	1380356.JNIK01000005_gene892	8.12e-117	385.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158416_k127_1147557_5	367299.JOEE01000002_gene2499	6.173e-33	133.0	COG1075@1|root,COG1075@2|Bacteria,2HEYP@201174|Actinobacteria,4FJ5C@85021|Intrasporangiaceae	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1147557_3	35754.JNYJ01000009_gene2063	1.029e-61	219.0	COG0500@1|root,COG2226@2|Bacteria,2GP9N@201174|Actinobacteria,4DFCN@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	Methyltransf_25
SRR25158416_k127_1147557_6	1385518.N798_11890	7.999e-30	121.0	COG4346@1|root,COG4346@2|Bacteria,2GITT@201174|Actinobacteria,4FEHH@85021|Intrasporangiaceae	201174|Actinobacteria	O	membrane	pmt	GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
SRR25158416_k127_1147557_7	1184609.KILIM_018_00500	6.714e-23	99.0	COG4346@1|root,COG4346@2|Bacteria,2GITT@201174|Actinobacteria,4F6EA@85018|Dermatophilaceae	201174|Actinobacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	pmt	GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
SRR25158416_k127_1157022_12	272134.KB731324_gene6617	3.103e-29	119.0	COG0451@1|root,COG0451@2|Bacteria,1G3KY@1117|Cyanobacteria,1HBRG@1150|Oscillatoriales	1117|Cyanobacteria	GM	NAD dependent epimerase dehydratase family	-	-	1.1.1.339	ko:K19180	ko00523,ko01130,map00523,map01130	-	R10190	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158416_k127_1157022_11	479432.Sros_0659	9.528e-31	124.0	COG0451@1|root,COG0451@2|Bacteria,2IRAH@201174|Actinobacteria	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_1157022_7	1120950.KB892752_gene6143	2.345e-80	272.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4DPFB@85009|Propionibacteriales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158416_k127_1157022_9	1032480.MLP_44890	4.962e-71	246.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4DQEY@85009|Propionibacteriales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158416_k127_1157022_1	479435.Kfla_5707	2.357e-169	537.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4DP73@85009|Propionibacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158416_k127_1157022_0	28042.GU90_04150	6.704e-194	616.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DZZ7@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158416_k127_1157022_2	479433.Caci_0167	1.261e-149	479.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158416_k127_1157022_5	1048339.KB913029_gene519	2.851e-97	329.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4ESFH@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_1157022_6	1095767.CAHD01000024_gene1747	1.307e-93	314.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158416_k127_1157022_8	1120950.KB892760_gene5758	3.601e-71	257.0	COG1686@1|root,COG1686@2|Bacteria,2GK3M@201174|Actinobacteria,4DTSB@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRR25158416_k127_1157022_10	479435.Kfla_1321	1.582e-62	229.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria,4DRBR@85009|Propionibacteriales	201174|Actinobacteria	J	LigT like Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158416_k127_1157022_3	477641.MODMU_4818	9.17e-143	461.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4ES9F@85013|Frankiales	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158416_k127_1157022_4	1120950.KB892760_gene5747	1.255e-110	364.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4DPDV@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158416_k127_1167429_3	404589.Anae109_1057	8e-17	89.0	COG0346@1|root,COG0346@2|Bacteria,1MV4D@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1167429_2	1380390.JIAT01000010_gene3929	5.761e-74	251.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4CT36@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1167429_0	1089545.KB913037_gene1339	4.92e-185	599.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4E1GD@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_1167429_1	1169161.KB897740_gene2304	1.235e-78	269.0	COG0346@1|root,COG0346@2|Bacteria,2IFBN@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1185985_1	1394178.AWOO02000066_gene137	8.186e-170	541.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4EHK5@85012|Streptosporangiales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158416_k127_1185985_0	1150864.MILUP08_42105	4.148e-177	560.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria,4DBMB@85008|Micromonosporales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158416_k127_1185985_2	1120949.KB903317_gene1732	1.679e-100	333.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DA13@85008|Micromonosporales	2|Bacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158416_k127_1220192_5	1120950.KB892779_gene860	7.13e-118	387.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4DTAB@85009|Propionibacteriales	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158416_k127_1220192_16	290315.Clim_0369	5.463e-35	141.0	COG0730@1|root,COG0730@2|Bacteria,1FF0W@1090|Chlorobi	1090|Chlorobi	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158416_k127_1220192_11	1869.MB27_28045	7.54e-52	189.0	COG0730@1|root,COG0730@2|Bacteria,2I9JV@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158416_k127_1220192_12	1206733.BAGC01000044_gene864	4.005e-49	177.0	COG3547@1|root,COG3547@2|Bacteria,2HJ5P@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_1220192_0	345341.KUTG_04019	4.275e-165	524.0	COG3547@1|root,COG3547@2|Bacteria,2HJ5P@201174|Actinobacteria,4E8DQ@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_1220192_15	1380393.JHVP01000009_gene1396	2.661e-35	139.0	COG2258@1|root,COG2258@2|Bacteria,2GRBQ@201174|Actinobacteria	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158416_k127_1220192_8	479435.Kfla_0799	3.184e-79	267.0	2C7GR@1|root,32H51@2|Bacteria,2IPDA@201174|Actinobacteria,4DVC4@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_29	67332.FM21_33900	1.724e-08	59.0	2E62U@1|root,330RX@2|Bacteria,2GTSM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_28	1120950.KB892748_gene3181	5.321e-11	68.0	COG2856@1|root,COG2856@2|Bacteria,2IFJ3@201174|Actinobacteria,4DT7X@85009|Propionibacteriales	201174|Actinobacteria	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_31,Peptidase_M78
SRR25158416_k127_1220192_6	1122611.KB903943_gene1422	2.24e-107	359.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4EHEG@85012|Streptosporangiales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_1220192_13	1125971.ASJB01000064_gene6633	6.466e-47	177.0	COG1546@1|root,COG1546@2|Bacteria,2IN1Q@201174|Actinobacteria,4E6NA@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the CinA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_33	44454.NF84_05865	2.466e-05	51.0	2DJKR@1|root,32UDA@2|Bacteria,2IQH2@201174|Actinobacteria,23AN7@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_32	1437824.BN940_13461	1.919e-06	51.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,2WB8T@28216|Betaproteobacteria,3T81Z@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_3	211114.JOEF01000010_gene3388	6.368e-120	392.0	COG0531@1|root,COG0531@2|Bacteria,2GM81@201174|Actinobacteria,4DY2G@85010|Pseudonocardiales	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_9	926554.KI912671_gene282	8.214e-72	250.0	COG0531@1|root,COG0531@2|Bacteria,1WIUU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_10	1150864.MILUP08_43844	8.478e-68	234.0	COG0531@1|root,COG0531@2|Bacteria,2GM81@201174|Actinobacteria,4DA0J@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_19	110319.CF8_0206	6.535e-32	137.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4DR27@85009|Propionibacteriales	201174|Actinobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158416_k127_1220192_1	1120948.KB903217_gene1147	9.626e-132	436.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,2GJB4@201174|Actinobacteria,4E215@85010|Pseudonocardiales	201174|Actinobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158416_k127_1220192_23	1048339.KB913029_gene1236	9.476e-17	84.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,4ES1S@85013|Frankiales	201174|Actinobacteria	S	PFAM metallophosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_1220192_30	928724.SacglDRAFT_00074	3.353e-08	60.0	COG2311@1|root,COG2311@2|Bacteria,2GQ7S@201174|Actinobacteria,4DXGX@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR25158416_k127_1220192_14	526225.Gobs_1646	1.149e-45	173.0	COG2311@1|root,COG2311@2|Bacteria,2GQ7S@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR25158416_k127_1220192_21	935866.JAER01000023_gene2331	4.413e-26	117.0	COG0711@1|root,COG0711@2|Bacteria,2IQQZ@201174|Actinobacteria,4DSWY@85009|Propionibacteriales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1220192_17	1122609.AUGT01000001_gene2802	1.121e-34	138.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4DSBW@85009|Propionibacteriales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158416_k127_1220192_22	2074.JNYD01000046_gene7323	7.655e-26	110.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria,4E5XH@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158416_k127_1220192_4	935866.JAER01000050_gene879	6.986e-119	398.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DN9S@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158416_k127_1220192_25	247156.NFA_15200	1.447e-13	75.0	2CIEV@1|root,30ANG@2|Bacteria,2GVCG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
SRR25158416_k127_1220192_7	1246448.ANAZ01000041_gene1131	2.042e-94	326.0	COG0464@1|root,COG0464@2|Bacteria,2GJHA@201174|Actinobacteria,4EIW6@85012|Streptosporangiales	201174|Actinobacteria	O	Protein of unknown function (DUF3631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3631
SRR25158416_k127_1220192_2	479432.Sros_1857	5.716e-128	423.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria,4EKAQ@85012|Streptosporangiales	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158416_k127_1220192_31	1146883.BLASA_1000	1.358e-06	55.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4ERKI@85013|Frankiales	201174|Actinobacteria	U	type II secretion system protein E	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158416_k127_1220192_20	204669.Acid345_3970	6.929e-28	116.0	2DQJB@1|root,3377V@2|Bacteria,3Y8JD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1224932_2	1122138.AQUZ01000001_gene1825	2.831e-65	227.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_1224932_0	1122138.AQUZ01000001_gene1826	1.191e-77	268.0	COG1277@1|root,COG1277@2|Bacteria,2H46W@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158416_k127_1224932_3	479435.Kfla_3509	8.94e-28	120.0	COG1572@1|root,COG1572@2|Bacteria,2H888@201174|Actinobacteria	201174|Actinobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1224932_1	1249634.D781_3805	2.982e-67	246.0	COG0477@1|root,COG2814@2|Bacteria,1NKUF@1224|Proteobacteria,1RV0D@1236|Gammaproteobacteria,404GZ@613|Serratia	1236|Gammaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_1224932_4	1121272.KB903255_gene5693	8.91e-24	111.0	COG1073@1|root,COG1073@2|Bacteria,2IPZT@201174|Actinobacteria,4DFKK@85008|Micromonosporales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH,Hydrolase_4
SRR25158416_k127_1240376_21	1033730.CAHG01000016_gene542	1.03e-08	60.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria,4DNCX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1240376_10	469383.Cwoe_0483	2.767e-95	322.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4CU5I@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1240376_19	263358.VAB18032_24245	5.111e-21	104.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DE78@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1240376_16	68170.KL590477_gene2552	7.428e-40	155.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4E5WC@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_1240376_20	696281.Desru_1524	6.721e-15	80.0	COG0723@1|root,COG0723@2|Bacteria,1VJ51@1239|Firmicutes,24T68@186801|Clostridia,264CW@186807|Peptococcaceae	186801|Clostridia	C	PFAM Rieske 2Fe-2S	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158416_k127_1240376_2	263358.VAB18032_21410	6.142e-188	603.0	COG1231@1|root,COG1231@2|Bacteria,2GMV0@201174|Actinobacteria,4DAKI@85008|Micromonosporales	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158416_k127_1240376_13	234621.RER_37070	1.2e-81	276.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria,4G8T5@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1240376_11	710111.FraQA3DRAFT_4238	1.046e-92	321.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4EV73@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_1240376_14	1380390.JIAT01000011_gene2452	1.425e-73	267.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4CS1Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
SRR25158416_k127_1240376_9	1380390.JIAT01000011_gene2451	1.413e-104	346.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CR9Y@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRR25158416_k127_1240376_8	1380390.JIAT01000011_gene2450	3.31e-110	372.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4CS8K@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158416_k127_1240376_4	926550.CLDAP_27920	4.67e-154	504.0	COG1858@1|root,COG2133@1|root,COG1858@2|Bacteria,COG2133@2|Bacteria,2G989@200795|Chloroflexi	200795|Chloroflexi	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
SRR25158416_k127_1240376_1	243233.MCA2161	2.204e-203	654.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1240376_0	479435.Kfla_5910	1.25e-208	662.0	COG2141@1|root,COG4639@1|root,COG2141@2|Bacteria,COG4639@2|Bacteria,2GM7W@201174|Actinobacteria,4DPZ7@85009|Propionibacteriales	201174|Actinobacteria	C	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
SRR25158416_k127_1240376_7	337191.KTR9_0614	4.517e-113	375.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4GH05@85026|Gordoniaceae	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,NAD_binding_8
SRR25158416_k127_1240376_6	266117.Rxyl_0526	1.468e-115	383.0	COG0665@1|root,COG0665@2|Bacteria,2GN2M@201174|Actinobacteria,4CSNB@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.3	ko:K00273	ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146	-	R00366,R02457,R02894,R02923,R04221,R07400	RC00006,RC00018,RC00135	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158416_k127_1240376_3	1463825.JNXC01000038_gene3353	1.005e-172	565.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria,4E1KA@85010|Pseudonocardiales	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SRR25158416_k127_1240376_17	746697.Aeqsu_0765	8.703e-34	135.0	COG5649@1|root,COG5649@2|Bacteria,4NPG5@976|Bacteroidetes,1I4MN@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158416_k127_1240376_18	446470.Snas_1907	2.075e-22	102.0	2DJKR@1|root,32UDA@2|Bacteria,2IQH2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1240376_12	1122609.AUGT01000001_gene2836	1.202e-87	307.0	COG3173@1|root,COG3173@2|Bacteria,2IA48@201174|Actinobacteria,4DR9I@85009|Propionibacteriales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_1240376_15	591158.SSMG_00819	2.819e-66	233.0	COG3832@1|root,COG3832@2|Bacteria,2IMFE@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_1240376_5	345341.KUTG_08457	5.869e-122	399.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4DY2Y@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_1243534_5	710111.FraQA3DRAFT_2348	1.807e-33	134.0	2ANI9@1|root,31DH5@2|Bacteria,2GJE8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1243534_2	1283283.ATXA01000013_gene3508	3.458e-73	252.0	COG0500@1|root,COG2226@2|Bacteria,2II6G@201174|Actinobacteria,4EUPA@85013|Frankiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_1243534_7	397291.C804_04348	2.353e-09	65.0	2DCQ6@1|root,2ZEXE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1243534_3	1454004.AW11_00407	1.168e-52	192.0	COG0012@1|root,COG0012@2|Bacteria,1Q097@1224|Proteobacteria,2W504@28216|Betaproteobacteria	28216|Betaproteobacteria	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1243534_4	1454004.AW11_00407	9.647e-48	182.0	COG0012@1|root,COG0012@2|Bacteria,1Q097@1224|Proteobacteria,2W504@28216|Betaproteobacteria	28216|Betaproteobacteria	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1243534_8	1454004.AW11_00407	1.206e-07	56.0	COG0012@1|root,COG0012@2|Bacteria,1Q097@1224|Proteobacteria,2W504@28216|Betaproteobacteria	28216|Betaproteobacteria	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1243534_9	378806.STAUR_7365	0.0004226	45.0	COG2963@1|root,COG2963@2|Bacteria,1MZ5C@1224|Proteobacteria,42WWI@68525|delta/epsilon subdivisions,2WSR8@28221|Deltaproteobacteria,2Z1X6@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158416_k127_1243534_6	405948.SACE_1239	2.707e-32	133.0	COG1309@1|root,COG1309@2|Bacteria,2GNK4@201174|Actinobacteria,4E5RM@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158416_k127_1243534_1	101510.RHA1_ro06946	2.206e-121	391.0	COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4FZ6U@85025|Nocardiaceae	201174|Actinobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158416_k127_1243534_0	101510.RHA1_ro06944	5.992e-172	552.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4FU1R@85025|Nocardiaceae	201174|Actinobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158416_k127_1244803_0	1304865.JAGF01000001_gene2054	2.358e-146	471.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4F10I@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
SRR25158416_k127_1244803_1	1120949.KB903312_gene606	5.178e-12	67.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR25158416_k127_1249860_2	886293.Sinac_0981	7.421e-30	126.0	COG2085@1|root,COG2085@2|Bacteria,2J3GA@203682|Planctomycetes	203682|Planctomycetes	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158416_k127_1249860_0	1396418.BATQ01000079_gene803	1.638e-101	335.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_32
SRR25158416_k127_1249860_1	1396418.BATQ01000079_gene803	1.337e-32	128.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_32
SRR25158416_k127_1249860_3	1089551.KE386572_gene1729	2.13e-12	69.0	COG0639@1|root,COG0639@2|Bacteria,1NFRY@1224|Proteobacteria,2UIZ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Domain of unknown function DUF29	-	-	-	-	-	-	-	-	-	-	-	-	DUF29
SRR25158416_k127_1250012_0	1385519.N801_12085	2.118e-147	470.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4FF68@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_1250012_1	1385520.N802_18165	1.553e-110	365.0	COG1277@1|root,COG1277@2|Bacteria,2INE4@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158416_k127_1250012_2	469383.Cwoe_3842	2.55e-75	261.0	COG0262@1|root,COG0262@2|Bacteria,2HG3A@201174|Actinobacteria,4CTPW@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1250239_9	1193181.BN10_1300016	5.432e-19	86.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1250239_8	591158.SSMG_05501	4.479e-24	104.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1250239_2	1449353.JQMQ01000005_gene1464	1.333e-184	587.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,2NHD0@228398|Streptacidiphilus	201174|Actinobacteria	J	tRNA synthetases class I (W and Y)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158416_k127_1250239_5	1120950.KB892768_gene5195	1.037e-79	270.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4DQWP@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	alkA	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158416_k127_1250239_0	1386089.N865_11245	7.078e-224	705.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4FF12@85021|Intrasporangiaceae	201174|Actinobacteria	E	Argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158416_k127_1250239_1	1134445.AJJM01000051_gene2110	7.279e-209	659.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1658	Arginosuc_synth
SRR25158416_k127_1250239_6	1048339.KB913029_gene4051	3.381e-59	215.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4ESWE@85013|Frankiales	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158416_k127_1250239_3	479435.Kfla_5434	2.925e-159	515.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4DNMX@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-III	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158416_k127_1250239_4	1120950.KB892768_gene5201	1.258e-134	436.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4DPCE@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158416_k127_1250239_7	795955.AFRW01000043_gene36	6.838e-37	140.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,1W87V@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158416_k127_1266317_1	502025.Hoch_2802	2.525e-63	227.0	COG1196@1|root,COG4913@1|root,COG1196@2|Bacteria,COG4913@2|Bacteria,1Q08W@1224|Proteobacteria,437XD@68525|delta/epsilon subdivisions,2X37A@28221|Deltaproteobacteria,2YUNW@29|Myxococcales	28221|Deltaproteobacteria	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
SRR25158416_k127_1266317_0	502025.Hoch_2872	3.962e-73	262.0	COG4924@1|root,COG4924@2|Bacteria,1QXCY@1224|Proteobacteria,4385V@68525|delta/epsilon subdivisions,2X3FP@28221|Deltaproteobacteria,2YVWJ@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
SRR25158416_k127_1290952_8	1121924.ATWH01000007_gene2120	4.293e-26	107.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4FR6F@85023|Microbacteriaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1290952_2	1283283.ATXA01000005_gene2208	2.405e-80	277.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4EWWQ@85013|Frankiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_1290952_3	680198.SCAB_14311	3.718e-79	278.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_1290952_10	1445613.JALM01000005_gene1186	6.394e-21	100.0	COG0346@1|root,COG0346@2|Bacteria,2H5Y5@201174|Actinobacteria,4EBMJ@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1290952_12	1237149.C900_00978	1.444e-14	79.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158416_k127_1290952_9	1120950.KB892801_gene1765	1.599e-23	108.0	COG0454@1|root,COG0456@2|Bacteria,2GQGN@201174|Actinobacteria,4DS9Y@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_1290952_11	1227487.C474_01537	1.107e-18	96.0	COG0500@1|root,arCOG02702@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158416_k127_1290952_5	1403819.BATR01000162_gene5394	5.888e-49	194.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158416_k127_1290952_4	675635.Psed_3794	1.447e-76	268.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4E709@85010|Pseudonocardiales	201174|Actinobacteria	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_1290952_0	1298863.AUEP01000017_gene4151	3.043e-98	340.0	COG2021@1|root,COG3629@1|root,COG2021@2|Bacteria,COG3629@2|Bacteria,2I3CQ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158416_k127_1290952_1	656024.FsymDg_2042	1.123e-83	288.0	COG2141@1|root,COG2141@2|Bacteria,2ID60@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_1290952_7	378806.STAUR_7416	1.453e-29	128.0	COG3217@1|root,COG3217@2|Bacteria,1N1P0@1224|Proteobacteria,43024@68525|delta/epsilon subdivisions,2X3J5@28221|Deltaproteobacteria,2YWAG@29|Myxococcales	28221|Deltaproteobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158416_k127_1290952_6	1461693.ATO10_09818	1.272e-39	157.0	COG3217@1|root,COG3217@2|Bacteria,1N1P0@1224|Proteobacteria,2UH9P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MOSC domain containing protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158416_k127_1298180_1	1504981.KO116_0205	2.003e-06	55.0	COG1396@1|root,COG4933@1|root,COG1396@2|Bacteria,COG4933@2|Bacteria,1N2JZ@1224|Proteobacteria,1SJS0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ASCH,HTH_3
SRR25158416_k127_1298180_0	1380386.JIAW01000026_gene6935	1.001e-83	283.0	COG1309@1|root,COG1309@2|Bacteria,2IGNJ@201174|Actinobacteria,238R0@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
SRR25158416_k127_1307980_0	543632.JOJL01000023_gene1803	2.52e-278	863.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4DAVT@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 3 family	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158416_k127_1341668_0	1121924.ATWH01000001_gene4268	3.395e-151	488.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4FKDZ@85023|Microbacteriaceae	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158416_k127_1341668_1	479435.Kfla_3886	4.925e-83	296.0	COG0580@1|root,COG0580@2|Bacteria,2GMG4@201174|Actinobacteria,4DQ3S@85009|Propionibacteriales	201174|Actinobacteria	G	Major intrinsic protein	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	MIP
SRR25158416_k127_1341668_2	468556.AQYG01000041_gene3588	4.853e-06	51.0	COG1733@1|root,COG1733@2|Bacteria,2IJCU@201174|Actinobacteria,4GGU0@85026|Gordoniaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158416_k127_1345120_1	1095769.CAHF01000021_gene882	8.254e-22	95.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,4747B@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158416_k127_1345120_0	1210046.B277_03345	1.11e-60	229.0	COG3103@1|root,COG3103@2|Bacteria,2IGZN@201174|Actinobacteria	201174|Actinobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1355061_47	408672.NBCG_01633	2.656e-34	137.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4DWM1@85009|Propionibacteriales	201174|Actinobacteria	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158416_k127_1355061_54	867903.ThesuDRAFT_02054	6.548e-17	95.0	COG0392@1|root,COG0392@2|Bacteria,1V1W5@1239|Firmicutes	1239|Firmicutes	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158416_k127_1355061_27	479432.Sros_8133	5.264e-97	343.0	COG1215@1|root,COG1215@2|Bacteria,2I3M7@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158416_k127_1355061_12	479432.Sros_8137	1.588e-174	558.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158416_k127_1355061_33	591158.SSMG_04424	1.104e-74	257.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria	201174|Actinobacteria	L	DNA alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158416_k127_1355061_8	1306174.JODP01000013_gene7756	1.437e-214	672.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_1355061_4	1120950.KB892748_gene3243	4.074e-293	924.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,4DPMD@85009|Propionibacteriales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158416_k127_1355061_24	1211815.CBYP010000068_gene189	1.584e-103	348.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4ESP8@85013|Frankiales	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158416_k127_1355061_6	351607.Acel_1393	9.969e-270	844.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4ES3F@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158416_k127_1355061_0	390989.JOEG01000002_gene4225	0.0	1469.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DBYB@85008|Micromonosporales	201174|Actinobacteria	C	aconitate hydratase	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158416_k127_1355061_15	512565.AMIS_18390	6.28e-137	445.0	COG0387@1|root,COG0387@2|Bacteria,2GJWT@201174|Actinobacteria,4D8I8@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	chaA	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	iNJ661.Rv1607	Na_Ca_ex
SRR25158416_k127_1355061_18	1112204.GPOL_c46600	3.06e-122	399.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4GAMM@85026|Gordoniaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158416_k127_1355061_5	1380356.JNIK01000003_gene1144	1.574e-272	860.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4ERRM@85013|Frankiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158416_k127_1355061_28	1944.JOAZ01000001_gene4067	1.04e-94	315.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,418VJ@629295|Streptomyces griseus group	201174|Actinobacteria	P	TrkA-C domain	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158416_k127_1355061_22	1122138.AQUZ01000029_gene4816	1.713e-107	353.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4DN0P@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-C domain	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158416_k127_1355061_41	1120950.KB892748_gene3215	1.126e-51	197.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4DQXN@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
SRR25158416_k127_1355061_48	1449346.JQMO01000003_gene5556	5.312e-34	134.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria,2M2XS@2063|Kitasatospora	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1355061_43	1120950.KB892748_gene3213	7.231e-45	171.0	28J4D@1|root,2Z90C@2|Bacteria,2GJYC@201174|Actinobacteria,4DRVJ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
SRR25158416_k127_1355061_38	1463825.JNXC01000002_gene4425	3.733e-61	223.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4E2RG@85010|Pseudonocardiales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158416_k127_1355061_49	1122609.AUGT01000012_gene4457	3.558e-26	116.0	2E4C2@1|root,32Z7M@2|Bacteria,2IFS5@201174|Actinobacteria,4DRWV@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3093)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3093
SRR25158416_k127_1355061_44	1120950.KB892748_gene3209	4.332e-43	170.0	2ATJW@1|root,31J3Z@2|Bacteria,2IKN0@201174|Actinobacteria,4DWJ1@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
SRR25158416_k127_1355061_26	1123320.KB889707_gene7992	1.253e-102	344.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158416_k127_1355061_30	1120950.KB892748_gene3207	6.649e-90	312.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DQIN@85009|Propionibacteriales	201174|Actinobacteria	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158416_k127_1355061_32	471852.Tcur_1692	1.606e-79	282.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4EG2I@85012|Streptosporangiales	201174|Actinobacteria	G	Inositol monophosphatase family	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158416_k127_1355061_14	110319.CF8_2403	3.505e-138	448.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,4DNBP@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158416_k127_1355061_29	1454010.JEOE01000050_gene2315	1.034e-91	317.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4F0M1@85016|Cellulomonadaceae	201174|Actinobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_1355061_17	1463857.JOFZ01000005_gene3186	7.174e-123	407.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase domain protein	gulO	-	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158416_k127_1355061_39	479435.Kfla_3498	1.048e-54	211.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,4DR1M@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3071)	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
SRR25158416_k127_1355061_40	479433.Caci_5299	5.575e-53	192.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158416_k127_1355061_51	479433.Caci_5300	3.123e-24	108.0	2E61P@1|root,333YK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1355061_16	1120950.KB892748_gene3186	1.347e-128	422.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4DNS7@85009|Propionibacteriales	201174|Actinobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158416_k127_1355061_35	1306990.BARG01000065_gene7461	1.297e-68	239.0	29850@1|root,2ZVAX@2|Bacteria,2GKR1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1355061_2	1120950.KB892768_gene5311	0.0	1067.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4DN4A@85009|Propionibacteriales	201174|Actinobacteria	CK	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158416_k127_1355061_37	935839.JAGJ01000004_gene2050	9.217e-65	229.0	29QBK@1|root,30BAT@2|Bacteria,2IH7J@201174|Actinobacteria,4F432@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1355061_1	1120950.KB892768_gene5322	0.0	1114.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4DPNM@85009|Propionibacteriales	201174|Actinobacteria	L	DNA Topoisomerase IV	gyrA2	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158416_k127_1355061_20	1122611.KB903975_gene3218	9.509e-114	370.0	COG0563@1|root,COG0563@2|Bacteria,2ICNJ@201174|Actinobacteria,4EMB9@85012|Streptosporangiales	201174|Actinobacteria	F	Adenylate kinase, active site lid	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158416_k127_1355061_7	66377.JOBH01000011_gene2374	3.09e-243	757.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria	201174|Actinobacteria	E	arginine	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158416_k127_1355061_31	1463903.JOIZ01000010_gene3606	4.92e-84	291.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria	201174|Actinobacteria	O	protein conserved in bacteria containing thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
SRR25158416_k127_1355061_11	1394178.AWOO02000092_gene1080	2.171e-175	555.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4EHDM@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158416_k127_1355061_3	1386089.N865_12475	1.73e-322	1002.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4FEA1@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158416_k127_1355061_52	1229203.KI301992_gene1441	1.056e-23	102.0	2E39Y@1|root,31HU6@2|Bacteria,2I1DN@201174|Actinobacteria,3UWZ6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1355061_45	1449069.JMLO01000028_gene4436	3.536e-40	158.0	COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria,4G1BR@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
SRR25158416_k127_1355061_21	1464048.JNZS01000029_gene1785	8.244e-110	371.0	COG0189@1|root,COG0189@2|Bacteria,2HI2Z@201174|Actinobacteria,4DBDA@85008|Micromonosporales	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
SRR25158416_k127_1355061_60	1172179.AUKV01000015_gene3269	4.024e-05	51.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158416_k127_1355061_57	1289387.AUKW01000009_gene4555	6.317e-11	70.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria	201174|Actinobacteria	H	Dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1355061_59	110319.CF8_4261	9.817e-06	54.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158416_k127_1355061_50	1214101.BN159_1174	5.901e-26	112.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158416_k127_1355061_10	1245471.PCA10_30630	3.989e-181	586.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158416_k127_1355061_46	1229780.BN381_360035	9.357e-39	153.0	arCOG06733@1|root,313GU@2|Bacteria,2ICAF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1355061_13	1449058.JQKT01000007_gene1902	5.085e-168	542.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,4FM2Z@85023|Microbacteriaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158416_k127_1355061_34	931627.MycrhDRAFT_1953	6.607e-72	249.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,234A6@1762|Mycobacteriaceae	201174|Actinobacteria	E	Monoamine oxidase	puo	-	1.4.3.10,1.4.3.4	ko:K00274,ko:K03343	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R01151,R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158416_k127_1355061_25	1121385.AQXW01000004_gene1390	1.617e-103	345.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria	201174|Actinobacteria	E	(mono)amine oxidase	puo	-	1.4.3.10,1.4.3.4	ko:K00274,ko:K03343	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R01151,R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158416_k127_1355061_58	51337.XP_004665816.1	2.543e-06	54.0	COG1231@1|root,KOG0029@2759|Eukaryota,38B4W@33154|Opisthokonta,3BI0V@33208|Metazoa,3CXJF@33213|Bilateria,484HM@7711|Chordata,492DD@7742|Vertebrata,3J61I@40674|Mammalia,35FYX@314146|Euarchontoglires,4Q14F@9989|Rodentia	33208|Metazoa	Q	primary amine oxidase activity	MAOB	GO:0000166,GO:0001505,GO:0002237,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0006091,GO:0006576,GO:0006584,GO:0006725,GO:0006807,GO:0008131,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009058,GO:0009308,GO:0009310,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009712,GO:0009719,GO:0009725,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010044,GO:0010269,GO:0014062,GO:0014063,GO:0014070,GO:0016020,GO:0016491,GO:0016638,GO:0016641,GO:0016999,GO:0017000,GO:0017144,GO:0018958,GO:0019222,GO:0019336,GO:0019439,GO:0019614,GO:0019867,GO:0022900,GO:0031090,GO:0031323,GO:0031325,GO:0031960,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032496,GO:0032879,GO:0033238,GO:0033240,GO:0033993,GO:0034641,GO:0036094,GO:0042053,GO:0042069,GO:0042133,GO:0042135,GO:0042221,GO:0042402,GO:0042417,GO:0042420,GO:0042424,GO:0042493,GO:0042737,GO:0042743,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043271,GO:0044106,GO:0044237,GO:0044248,GO:0044249,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045471,GO:0045915,GO:0045964,GO:0046677,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0050660,GO:0050662,GO:0050665,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051384,GO:0051385,GO:0051412,GO:0051588,GO:0051589,GO:0051704,GO:0051707,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072593,GO:0080090,GO:0097159,GO:0097164,GO:0097305,GO:0098588,GO:0098805,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901615,GO:1901616,GO:1901654,GO:1901700,GO:1903409,GO:1903530,GO:1903531	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158416_k127_1355061_9	1095767.CAHD01000197_gene513	5.302e-192	613.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4F127@85016|Cellulomonadaceae	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_1355061_36	1463881.KL591004_gene3708	7.677e-68	239.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158416_k127_1355061_42	479435.Kfla_3427	4.894e-51	194.0	COG0589@1|root,COG0589@2|Bacteria,2IR3G@201174|Actinobacteria,4DRRV@85009|Propionibacteriales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158416_k127_1355061_23	1211815.CBYP010000063_gene1845	5.482e-106	357.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4EUCQ@85013|Frankiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158416_k127_1355061_19	196162.Noca_0015	3.161e-118	390.0	COG0204@1|root,COG0204@2|Bacteria,2I8I4@201174|Actinobacteria,4DTB6@85009|Propionibacteriales	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158416_k127_1355061_55	1048339.KB913029_gene3833	4.544e-16	88.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4ESAZ@85013|Frankiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158416_k127_1360085_3	1122182.KB903837_gene3780	3.474e-68	243.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DF2R@85008|Micromonosporales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_1360085_1	593907.Celgi_1147	4.984e-118	383.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4F0GE@85016|Cellulomonadaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158416_k127_1360085_0	471857.Svir_09060	7.063e-264	818.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4DZ56@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158416_k127_1360085_2	479435.Kfla_4858	8.224e-88	304.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4DPSM@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2987c	Aconitase_C
SRR25158416_k127_1360085_4	1122609.AUGT01000004_gene1309	8.383e-37	156.0	COG0776@1|root,COG1754@1|root,COG0776@2|Bacteria,COG1754@2|Bacteria,2GV0M@201174|Actinobacteria,4DR53@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the bacterial histone-like protein family	hup	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158416_k127_1380515_3	47763.JNZA01000022_gene2753	6.946e-18	84.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158416_k127_1380515_2	1380390.JIAT01000010_gene4020	1.016e-23	106.0	COG0662@1|root,COG0662@2|Bacteria,2HRRH@201174|Actinobacteria,4CTU5@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_1380515_1	1121272.KB903291_gene3442	2.694e-116	381.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4DB65@85008|Micromonosporales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_1380515_0	1449976.KALB_1660	4.273e-145	468.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJX@85010|Pseudonocardiales	201174|Actinobacteria	V	Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158416_k127_1380515_4	47763.JNZA01000009_gene5571	2.351e-10	61.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158416_k127_1381213_2	479432.Sros_8959	6.72e-58	211.0	COG0500@1|root,COG2226@2|Bacteria,2IP4P@201174|Actinobacteria,4EKAN@85012|Streptosporangiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158416_k127_1381213_0	298655.KI912266_gene4387	5.821e-102	339.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03088,ko:K07110	-	-	-	-	ko00000,ko03000,ko03021	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
SRR25158416_k127_1381213_1	298655.KI912266_gene4388	2.008e-59	221.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	mip	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158416_k127_1381213_4	479431.Namu_0432	0.0001471	52.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_1381213_3	1122611.KB903940_gene1923	5.295e-08	57.0	28QKY@1|root,2ZD2Q@2|Bacteria,2IM53@201174|Actinobacteria,4EQNC@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1385775_4	1121374.KB891576_gene219	6.212e-05	48.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
SRR25158416_k127_1385775_3	479432.Sros_8898	2.767e-08	64.0	2EA47@1|root,33494@2|Bacteria,2GPU6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SRR25158416_k127_1385775_0	526225.Gobs_2584	3.892e-160	508.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_1385775_1	146922.JOFU01000062_gene89	4.532e-100	334.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158416_k127_1385775_2	1380393.JHVP01000001_gene2696	1.151e-40	153.0	2E0MI@1|root,32W6Q@2|Bacteria,2IQTZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1386693_4	390989.JOEG01000016_gene5660	4.459e-16	80.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4DAUI@85008|Micromonosporales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158416_k127_1386693_0	653045.Strvi_6073	3.351e-218	683.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	adhfe	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158416_k127_1386693_2	471853.Bcav_2792	3.3e-63	224.0	COG2764@1|root,COG2764@2|Bacteria,2IMGA@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1386693_1	477641.MODMU_2135	1.553e-95	323.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4EVWX@85013|Frankiales	201174|Actinobacteria	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158416_k127_1386693_3	1380347.JNII01000005_gene3189	1.499e-53	192.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4ETX5@85013|Frankiales	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	xyoA	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158416_k127_1387583_1	397278.JOJN01000004_gene1165	1.076e-92	308.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4DNEE@85009|Propionibacteriales	201174|Actinobacteria	C	cytochrome c oxidase subunit III	ctaE	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158416_k127_1387583_0	479435.Kfla_2788	8.953e-95	319.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,4DPAK@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158416_k127_1387583_2	1120950.KB892707_gene4799	1.137e-39	155.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4DNGA@85009|Propionibacteriales	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158416_k127_1398601_0	1380347.JNII01000007_gene509	1.216e-98	331.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,4ERU4@85013|Frankiales	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158416_k127_1398601_1	35754.JNYJ01000061_gene2355	6.077e-90	304.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4DDPM@85008|Micromonosporales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_1398601_2	35754.JNYJ01000061_gene2353	3.349e-84	286.0	COG1476@1|root,COG1476@2|Bacteria,2I3S1@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158416_k127_1398601_8	469371.Tbis_1699	7.295e-17	87.0	2E89B@1|root,332N6@2|Bacteria,2IMU0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1398601_4	1449069.JMLO01000016_gene3394	4.836e-55	197.0	COG0748@1|root,COG0748@2|Bacteria,2IFYD@201174|Actinobacteria,4G9EE@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_1398601_3	1312954.KI914852_gene538	1.754e-83	290.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_1398601_12	710686.Mycsm_04185	0.0002601	52.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,23AX1@1762|Mycobacteriaceae	201174|Actinobacteria	K	arsR family	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158416_k127_1398601_7	1385520.N802_05925	1.054e-21	99.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF5011,FG-GAP_2,NHL
SRR25158416_k127_1398601_9	568076.XP_007825214.1	5.211e-15	80.0	COG0436@1|root,KOG0257@2759|Eukaryota,38BZ0@33154|Opisthokonta,3NVUU@4751|Fungi,3QPSJ@4890|Ascomycota,2173B@147550|Sordariomycetes,3THW4@5125|Hypocreales,3G248@34397|Clavicipitaceae	4751|Fungi	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158416_k127_1398601_5	290399.Arth_3787	6.52e-52	189.0	COG0436@1|root,COG0436@2|Bacteria,2ID0T@201174|Actinobacteria	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158416_k127_1398601_10	479432.Sros_7450	4.039e-13	78.0	COG3801@1|root,COG3801@2|Bacteria,2INK4@201174|Actinobacteria,4EJTZ@85012|Streptosporangiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158416_k127_1398601_6	471853.Bcav_2673	3.374e-40	153.0	COG0251@1|root,COG0251@2|Bacteria,2IKQ2@201174|Actinobacteria	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_1399310_3	177437.HRM2_10590	1.473e-14	85.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria	1224|Proteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF900,Peptidase_C1
SRR25158416_k127_1399310_0	1179773.BN6_06000	1.027e-52	192.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria,4E51C@85010|Pseudonocardiales	201174|Actinobacteria	P	TIGRFAM deazaflavin-dependent nitroreductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_1399310_2	1120950.KB892772_gene1119	2.71e-25	106.0	2BB4Q@1|root,324M3@2|Bacteria,2H9HU@201174|Actinobacteria,4DWEJ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1399310_1	219305.MCAG_04750	5.583e-31	122.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DA3W@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_1401892_2	446462.Amir_0618	4.556e-86	289.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4DY5K@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, deoR family	glpR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
SRR25158416_k127_1401892_0	1120950.KB892760_gene5746	2.438e-158	517.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4DQ5F@85009|Propionibacteriales	201174|Actinobacteria	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SRR25158416_k127_1401892_1	1120950.KB892760_gene5745	1.392e-129	420.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4DQX1@85009|Propionibacteriales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158416_k127_1401892_3	1184609.KILIM_005_01400	6.316e-69	241.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4F6Q9@85018|Dermatophilaceae	201174|Actinobacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158416_k127_1412530_7	1210046.B277_15093	1.876e-53	197.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4FFV4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158416_k127_1412530_4	1120950.KB892743_gene3153	2.187e-93	318.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4DNQV@85009|Propionibacteriales	201174|Actinobacteria	EH	Peptidase C26	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158416_k127_1412530_2	269800.Tfu_3066	7.51e-149	492.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EFPA@85012|Streptosporangiales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_1412530_6	762948.HMPREF0733_10947	1.49e-70	255.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GMPZ@201174|Actinobacteria,1W7XS@1268|Micrococcaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_1412530_0	1120950.KB892743_gene3151	8.322e-163	536.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4DP0A@85009|Propionibacteriales	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158416_k127_1412530_1	935866.JAER01000017_gene4377	6.29e-154	509.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4DPN4@85009|Propionibacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158416_k127_1412530_3	981369.JQMJ01000003_gene7393	4.714e-94	327.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,2NHFZ@228398|Streptacidiphilus	201174|Actinobacteria	T	Protein phosphatase 2C	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158416_k127_1412530_8	585531.HMPREF0063_10449	6.906e-42	163.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4DQIX@85009|Propionibacteriales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158416_k127_1412530_5	1229203.KI301992_gene2644	2.537e-75	263.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,3UWPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158416_k127_1412530_10	222534.KB893761_gene3562	6.275e-08	57.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4EU5A@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_1412530_9	1125971.ASJB01000074_gene68	1.775e-09	61.0	COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria,4DX4R@85010|Pseudonocardiales	201174|Actinobacteria	CG	lipid glycosylation	gtfE	GO:0003674,GO:0003824,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016999,GO:0017000,GO:0017144,GO:0019184,GO:0030650,GO:0030651,GO:0033071,GO:0033072,GO:0034641,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_transf_28,UDPGT
SRR25158416_k127_1414938_0	526225.Gobs_3079	2.333e-284	881.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4EUUN@85013|Frankiales	201174|Actinobacteria	G	Evidence 2b Function of strongly homologous gene	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR25158416_k127_1414938_1	1211815.CBYP010000002_gene1998	5.527e-13	68.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4ERMY@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_1448801_0	926550.CLDAP_34350	3.111e-62	228.0	COG0671@1|root,COG0671@2|Bacteria,2G984@200795|Chloroflexi	200795|Chloroflexi	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158416_k127_1448801_2	929703.KE386491_gene486	3.439e-07	52.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47JAV@768503|Cytophagia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158416_k127_1448801_1	35754.JNYJ01000014_gene4869	9.996e-30	121.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4DBVX@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158416_k127_1452253_5	1211815.CBYP010000012_gene528	1.075e-13	79.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158416_k127_1452253_1	479435.Kfla_5617	2.629e-101	340.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4DQ35@85009|Propionibacteriales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_1452253_0	479435.Kfla_5618	3.877e-130	424.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DNPQ@85009|Propionibacteriales	201174|Actinobacteria	V	daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158416_k127_1452253_4	1120950.KB892763_gene5546	3.113e-37	146.0	COG3877@1|root,COG3877@2|Bacteria,2IT3M@201174|Actinobacteria,4DVDP@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRR25158416_k127_1452253_3	1120950.KB892763_gene5545	2.652e-62	223.0	2B5R0@1|root,31YKI@2|Bacteria,2IPMA@201174|Actinobacteria,4DR93@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1452253_2	1157637.KB892113_gene4916	4.017e-101	334.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158416_k127_1458223_1	1380347.JNII01000005_gene3108	1.144e-58	211.0	COG1917@1|root,COG2114@1|root,COG1917@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158416_k127_1458223_0	1229203.KI301992_gene226	1.335e-237	738.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,3UWAV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158416_k127_1465447_5	1380370.JIBA01000012_gene3751	1.425e-68	233.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,4FGJN@85021|Intrasporangiaceae	201174|Actinobacteria	H	Deaminase reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1465447_2	1172188.KB911822_gene1168	9.725e-159	503.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4FFEX@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_1465447_8	1121019.AUMN01000038_gene23	4.549e-21	101.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_1465447_3	1122138.AQUZ01000005_gene2505	8.021e-122	410.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4DNAA@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_1465447_0	196162.Noca_1675	4.17e-302	941.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4DNCN@85009|Propionibacteriales	201174|Actinobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
SRR25158416_k127_1465447_9	1298863.AUEP01000012_gene3675	0.0001799	49.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_1465447_1	106370.Francci3_0244	1.134e-219	695.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4ETT2@85013|Frankiales	201174|Actinobacteria	K	Sigma-70, region 4 type 2	sigI	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_1465447_6	67356.KL575601_gene7886	1.413e-61	220.0	COG3795@1|root,COG3795@2|Bacteria,2IFD6@201174|Actinobacteria	201174|Actinobacteria	V	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158416_k127_1465447_7	1449976.KALB_2841	9.257e-27	115.0	2BXAF@1|root,348J4@2|Bacteria,2GZTK@201174|Actinobacteria,4ED22@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1465447_4	1123320.KB889563_gene6499	3.79e-117	381.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_1496037_4	1120950.KB892776_gene796	3.147e-177	562.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DP99@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158416_k127_1496037_2	1380393.JHVP01000005_gene3585	5.102e-192	619.0	COG2382@1|root,COG2382@2|Bacteria,2I844@201174|Actinobacteria,4EWT7@85013|Frankiales	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
SRR25158416_k127_1496037_10	1380393.JHVP01000005_gene3586	7.038e-89	304.0	COG3340@1|root,COG3340@2|Bacteria,2IGG2@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158416_k127_1496037_0	1380393.JHVP01000005_gene3587	4.449e-220	687.0	COG0151@1|root,COG0151@2|Bacteria,2I624@201174|Actinobacteria,4EXFF@85013|Frankiales	201174|Actinobacteria	F	Carbamoyl-phosphate synthase L chain, ATP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1496037_3	1380393.JHVP01000005_gene3588	1.699e-190	604.0	COG1181@1|root,COG1181@2|Bacteria,2I7XS@201174|Actinobacteria,4EWIZ@85013|Frankiales	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	ATP-grasp_4,Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158416_k127_1496037_1	1380393.JHVP01000005_gene3589	7.296e-195	614.0	COG1181@1|root,COG1181@2|Bacteria,2I7XS@201174|Actinobacteria,4EWIZ@85013|Frankiales	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	ATP-grasp,ATP-grasp_4,Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158416_k127_1496037_5	1120950.KB892790_gene2100	7.355e-165	529.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4DMZ8@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158416_k127_1496037_7	1380393.JHVP01000005_gene3591	4.796e-113	370.0	COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria,4EWIE@85013|Frankiales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158416_k127_1496037_15	945712.CULC22_00471	2.878e-16	83.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,22NM6@1653|Corynebacteriaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	wblB	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158416_k127_1496037_11	1906.SFRA_14560	2.025e-80	284.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria	201174|Actinobacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158416_k127_1496037_12	543632.JOJL01000017_gene10028	1.694e-44	168.0	COG0640@1|root,COG0640@2|Bacteria,2IS0F@201174|Actinobacteria,4DF2V@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_1496037_9	1120950.KB892749_gene3331	2.99e-98	336.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4DP19@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158416_k127_1496037_8	1123320.KB889733_gene6266	3.437e-110	361.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria	201174|Actinobacteria	G	inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158416_k127_1496037_14	313589.JNB_10329	3.76e-20	96.0	COG5274@1|root,COG5274@2|Bacteria,2HUTH@201174|Actinobacteria,4FHNW@85021|Intrasporangiaceae	201174|Actinobacteria	CI	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1496037_6	1283283.ATXA01000016_gene43	6.558e-141	452.0	COG2267@1|root,COG2267@2|Bacteria,2IMQ0@201174|Actinobacteria,4EUVE@85013|Frankiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158416_k127_1496037_13	1120950.KB892749_gene3327	7.043e-30	119.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,4DNJ3@85009|Propionibacteriales	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158416_k127_15106_0	1123322.KB904634_gene2305	5.874e-216	675.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158416_k127_15106_1	390989.JOEG01000012_gene3462	2.264e-111	378.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_1523942_2	67281.JNZZ01000008_gene5544	6.086e-24	103.0	2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,41B1X@629295|Streptomyces griseus group	201174|Actinobacteria	D	Cell division protein CrgA	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
SRR25158416_k127_1523942_1	1463858.JOHR01000005_gene1286	5.217e-76	264.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria	201174|Actinobacteria	NU	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158416_k127_1523942_0	1298880.AUEV01000004_gene2030	3.427e-83	280.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	cypB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158416_k127_1523942_3	593907.Celgi_0020	0.0002961	52.0	2DD1M@1|root,2ZG5Q@2|Bacteria,2IFGU@201174|Actinobacteria,4F1EX@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_153356_0	1380354.JIAN01000008_gene3319	2.02e-129	419.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_153356_1	1068978.AMETH_1273	8.328e-128	422.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
SRR25158416_k127_153356_8	1463920.JOGB01000009_gene837	4.745e-18	89.0	COG2208@1|root,COG2208@2|Bacteria,2GJSK@201174|Actinobacteria	201174|Actinobacteria	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c_2,PAS_3,PAS_4,SpoIIE
SRR25158416_k127_153356_11	909613.UO65_3692	1.544e-12	71.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158416_k127_153356_5	1071679.BG57_17010	1.969e-38	149.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2VQ5D@28216|Betaproteobacteria,1JZNC@119060|Burkholderiaceae	28216|Betaproteobacteria	J	endoribonuclease L-PSP	tdcF2	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158416_k127_153356_2	1304865.JAGF01000001_gene3272	2.433e-112	378.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.14,1.1.1.303,1.1.1.4	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	M00014	R00875,R01896,R02855,R02946,R10504	RC00085,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_153356_4	1298863.AUEP01000002_gene1559	2.385e-67	233.0	COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria,4DR4S@85009|Propionibacteriales	201174|Actinobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_153356_10	436229.JOEH01000025_gene1000	3.412e-15	77.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria,2NJ5R@228398|Streptacidiphilus	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_153356_9	1150864.MILUP08_42675	2.949e-17	83.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4DB2V@85008|Micromonosporales	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_153356_3	1122132.AQYH01000019_gene232	2.119e-102	348.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TUM5@28211|Alphaproteobacteria,4B84R@82115|Rhizobiaceae	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SRR25158416_k127_153356_7	416591.Tlet_1576	5.24e-22	105.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_153356_6	1089545.KB913037_gene8416	6.379e-36	139.0	COG1266@1|root,COG1266@2|Bacteria,2HRED@201174|Actinobacteria,4EAKF@85010|Pseudonocardiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158416_k127_1544222_1	1077972.ARGLB_083_00800	3.301e-57	206.0	COG1266@1|root,COG1266@2|Bacteria,2HVFD@201174|Actinobacteria,1WBSF@1268|Micrococcaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158416_k127_1544222_0	1380390.JIAT01000010_gene4195	2.387e-109	374.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CSC0@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158416_k127_1544222_2	1283299.AUKG01000002_gene4675	1.125e-43	164.0	COG2197@1|root,COG2197@2|Bacteria,2HQF1@201174|Actinobacteria,4CRZT@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_1546281_5	1121933.AUHH01000018_gene2819	3.152e-22	99.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158416_k127_1546281_4	67267.JNXT01000024_gene4517	6.119e-24	104.0	COG2353@1|root,COG2353@2|Bacteria,2IH61@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158416_k127_1546281_2	247156.NFA_21180	5.648e-25	111.0	COG1396@1|root,COG1396@2|Bacteria,2IP35@201174|Actinobacteria,4FURM@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_1546281_10	1206739.BAGJ01000091_gene1237	2.795e-05	50.0	COG1396@1|root,COG1396@2|Bacteria,2IP35@201174|Actinobacteria,4FURM@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_1546281_7	105425.BBPL01000038_gene2903	4.992e-11	67.0	COG1396@1|root,COG1396@2|Bacteria,2I90F@201174|Actinobacteria,2NKU7@228398|Streptacidiphilus	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_1546281_0	1206737.BAGF01000084_gene5485	6.82e-88	301.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4FUZK@85025|Nocardiaceae	201174|Actinobacteria	EG	EamA-like transporter family	cyeA	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_1546281_11	1869.MB27_26320	0.0008695	50.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria,4DCA4@85008|Micromonosporales	201174|Actinobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRR25158416_k127_1546281_6	1206737.BAGF01000006_gene414	4.39e-18	95.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria,4FXZE@85025|Nocardiaceae	201174|Actinobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRR25158416_k127_1546281_8	1123508.JH636444_gene5420	1.067e-09	66.0	2DBCA@1|root,2Z8CB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1546281_3	1172179.AUKV01000012_gene5299	9.236e-25	114.0	290B1@1|root,2ZN0K@2|Bacteria,2IFT1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1546281_9	1120971.AUCA01000025_gene790	1.502e-08	58.0	COG3335@1|root,COG3335@2|Bacteria,1U2YN@1239|Firmicutes,4HX7V@91061|Bacilli,27A4T@186823|Alicyclobacillaceae	91061|Bacilli	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR25158416_k127_1546281_1	2074.JNYD01000048_gene735	5.118e-25	104.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZ4K@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158416_k127_1558976_3	1048339.KB913029_gene4706	1.794e-16	83.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4EUGA@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_1558976_0	479431.Namu_2599	3.112e-258	807.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria,4EVSA@85013|Frankiales	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
SRR25158416_k127_1558976_2	1229780.BN381_750002	2.867e-26	114.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1558976_1	1157634.KB912971_gene1789	2.432e-87	298.0	2E96W@1|root,333FE@2|Bacteria,2IE1Q@201174|Actinobacteria	201174|Actinobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158416_k127_1558976_6	1120949.KB903306_gene7390	0.0008092	49.0	2DGHJ@1|root,2ZW0N@2|Bacteria,2GXBZ@201174|Actinobacteria,4DGG8@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1558976_5	1122130.AUHN01000005_gene2294	0.0004605	44.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158416_k127_1559033_12	477641.MODMU_3142	3.011e-36	152.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESP4@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_1559033_16	234267.Acid_4282	1.971e-19	93.0	COG5485@1|root,COG5485@2|Bacteria,3Y8NT@57723|Acidobacteria	57723|Acidobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158416_k127_1559033_5	118163.Ple7327_4457	2.555e-121	399.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,3VIG5@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_1559033_1	479434.Sthe_1229	3.308e-159	519.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_1559033_15	1313172.YM304_31100	2.702e-24	106.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158416_k127_1559033_8	1380390.JIAT01000009_gene669	3.834e-73	280.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158416_k127_1559033_19	479433.Caci_6845	2.884e-08	64.0	COG1595@1|root,COG1595@2|Bacteria,2I13R@201174|Actinobacteria	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1559033_13	1068980.ARVW01000001_gene1413	1.126e-34	142.0	2E534@1|root,32ZWA@2|Bacteria,2I9VJ@201174|Actinobacteria,4E5BX@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2637)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2637
SRR25158416_k127_1559033_2	1120950.KB892766_gene5124	1.108e-156	515.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	CHRD,DUF839,HemolysinCabind,Phytase-like
SRR25158416_k127_1559033_18	1283283.ATXA01000001_gene471	5.33e-11	70.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4EW1Q@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158416_k127_1559033_11	1214242.B446_28360	2.547e-45	177.0	COG1881@1|root,COG1881@2|Bacteria,2IIR9@201174|Actinobacteria	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	lppC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158416_k127_1559033_3	926550.CLDAP_34350	7.188e-124	416.0	COG0671@1|root,COG0671@2|Bacteria,2G984@200795|Chloroflexi	200795|Chloroflexi	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158416_k127_1559033_0	298653.Franean1_6569	8.671e-166	559.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EUDE@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
SRR25158416_k127_1559033_10	479431.Namu_5089	2.413e-53	201.0	COG0454@1|root,COG0456@2|Bacteria,2HP83@201174|Actinobacteria,4EW4F@85013|Frankiales	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1559033_4	67267.JNXT01000046_gene6352	1.022e-121	415.0	COG0457@1|root,COG0457@2|Bacteria	67267.JNXT01000046_gene6352|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1559033_6	284031.JNXD01000040_gene7170	5.28e-117	385.0	COG0596@1|root,COG0596@2|Bacteria,2I4XA@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158416_k127_1559033_7	401053.AciPR4_3726	1.096e-105	351.0	COG0596@1|root,COG0596@2|Bacteria,3Y610@57723|Acidobacteria,2JKYJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158416_k127_1559033_9	502025.Hoch_0043	2.176e-72	257.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,42N6J@68525|delta/epsilon subdivisions,2WJ0W@28221|Deltaproteobacteria,2Z08Y@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1559033_14	1440053.JOEI01000044_gene6951	7.167e-31	132.0	COG3629@1|root,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158416_k127_1559033_22	439292.Bsel_1517	0.0005154	49.0	COG1413@1|root,COG1413@2|Bacteria,1VG5Z@1239|Firmicutes,4HP2U@91061|Bacilli	91061|Bacilli	C	Scaffold protein Nfu NifU	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N
SRR25158416_k127_1569568_0	479431.Namu_2599	1.993e-207	659.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria,4EVSA@85013|Frankiales	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
SRR25158416_k127_1569568_2	1229780.BN381_750002	4.355e-30	124.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1569568_1	1449044.JMLE01000021_gene1959	1.762e-40	151.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158416_k127_1591421_5	1961.JOAK01000012_gene6236	2.939e-05	48.0	2EFF7@1|root,33981@2|Bacteria,2IFB2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1591421_3	1463825.JNXC01000013_gene7834	3.163e-25	105.0	2E39N@1|root,32Y97@2|Bacteria,2GQFF@201174|Actinobacteria,4E6N0@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3117
SRR25158416_k127_1591421_1	58123.JOFJ01000015_gene4522	3.81e-88	305.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4EHQ8@85012|Streptosporangiales	201174|Actinobacteria	K	PaaX-like protein	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158416_k127_1591421_0	1123320.KB889719_gene7358	2.695e-95	321.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	chcB	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158416_k127_1591421_2	1157637.KB892113_gene5037	1.338e-80	274.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria	201174|Actinobacteria	L	Glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158416_k127_1591421_4	477641.MODMU_1150	1.045e-06	50.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4ETJ6@85013|Frankiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_1599810_1	1136417.AZWE01000043_gene3213	2.273e-151	502.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4D9CY@85008|Micromonosporales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
SRR25158416_k127_1599810_2	1380347.JNII01000011_gene967	8.296e-60	214.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria	201174|Actinobacteria	S	membrane	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
SRR25158416_k127_1599810_3	2002.JOEQ01000007_gene1884	6.216e-58	209.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria,4EJ0N@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158416_k127_1599810_0	351607.Acel_1818	8.62e-158	507.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4ERJN@85013|Frankiales	201174|Actinobacteria	P	CBS domain	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRR25158416_k127_1602022_1	285535.JOEY01000090_gene7695	5.53e-85	282.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria	201174|Actinobacteria	H	reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1602022_0	478801.Ksed_00660	3.441e-212	666.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158416_k127_1605103_2	1380370.JIBA01000015_gene318	3.037e-07	53.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4FFEB@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_1605103_1	1121924.ATWH01000008_gene764	1.513e-89	299.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4FR0W@85023|Microbacteriaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_1605103_0	1121924.ATWH01000008_gene765	2.211e-211	672.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4FP8H@85023|Microbacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_1605103_3	263358.VAB18032_16525	0.000186	48.0	COG3339@1|root,COG3339@2|Bacteria,2IMCR@201174|Actinobacteria,4DGJP@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158416_k127_1610_2	536019.Mesop_2610	3.106e-09	70.0	28I6F@1|root,2Z89G@2|Bacteria,1R1D8@1224|Proteobacteria,2U4Y9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1610_3	1336208.JADY01000002_gene250	0.0001182	54.0	COG0438@1|root,COG2227@1|root,COG0438@2|Bacteria,COG2227@2|Bacteria,1QW4Q@1224|Proteobacteria,2U3B0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR25158416_k127_1610_0	1550073.JROH01000003_gene2422	8.982e-38	152.0	COG0030@1|root,COG0030@2|Bacteria,1R1XJ@1224|Proteobacteria,2TZ6Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158416_k127_1610_1	1150864.MILUP08_43219	9.478e-26	120.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158416_k127_1617908_7	1304865.JAGF01000001_gene715	1.659e-242	783.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_1617908_58	1184607.AUCHE_01_01260	3.155e-57	201.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4F70I@85018|Dermatophilaceae	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158416_k127_1617908_53	67315.JOBD01000016_gene6435	1.183e-64	230.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158416_k127_1617908_74	1283299.AUKG01000005_gene48	2.277e-34	139.0	COG0494@1|root,COG0494@2|Bacteria,2I7H5@201174|Actinobacteria	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158416_k127_1617908_44	1298863.AUEP01000002_gene1392	5.149e-88	301.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4DPWD@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158416_k127_1617908_62	1120950.KB892769_gene5386	2.611e-53	193.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4DR0E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158416_k127_1617908_71	1120950.KB892769_gene5382	1.433e-39	151.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4DRQN@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158416_k127_1617908_18	1449347.JQLN01000005_gene3393	4.162e-172	557.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,2M15S@2063|Kitasatospora	201174|Actinobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158416_k127_1617908_42	105425.BBPL01000006_gene7299	2.829e-93	321.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,2NGBY@228398|Streptacidiphilus	201174|Actinobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158416_k127_1617908_31	196162.Noca_3245	1.038e-113	379.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DN7T@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_1617908_68	298654.FraEuI1c_1079	4.095e-43	166.0	COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4ET1M@85013|Frankiales	201174|Actinobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158416_k127_1617908_47	1068980.ARVW01000001_gene5648	8.516e-78	267.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria,4E3U9@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1617908_26	469371.Tbis_0994	3.51e-132	433.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4DZ1Y@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158416_k127_1617908_36	1120950.KB892747_gene3745	2.584e-107	355.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4DNDW@85009|Propionibacteriales	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158416_k127_1617908_33	367299.JOEE01000004_gene1197	5.163e-111	364.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4FE89@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158416_k127_1617908_45	1048339.KB913029_gene3531	6.942e-81	273.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4ESC9@85013|Frankiales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158416_k127_1617908_43	1211815.CBYP010000038_gene2180	5.752e-89	306.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4ES47@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158416_k127_1617908_13	649831.L083_4851	7.949e-199	630.0	COG1181@1|root,COG1181@2|Bacteria,2HP1M@201174|Actinobacteria,4DHKT@85008|Micromonosporales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C
SRR25158416_k127_1617908_81	1048339.KB913029_gene4569	3.473e-06	58.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4ET2B@85013|Frankiales	201174|Actinobacteria	D	PFAM DivIVA family protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158416_k127_1617908_69	1172180.KB911793_gene3623	3.401e-41	164.0	COG0346@1|root,COG0346@2|Bacteria,2IM0I@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Glyoxalase_4
SRR25158416_k127_1617908_9	1033730.CAHG01000006_gene1164	4.779e-217	683.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DNDH@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_1617908_29	1054860.KB913030_gene5513	9.267e-121	396.0	COG1619@1|root,COG1619@2|Bacteria,2I358@201174|Actinobacteria	201174|Actinobacteria	V	peptidase U61	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158416_k127_1617908_72	84531.JMTZ01000038_gene3588	8.463e-39	152.0	2EFPP@1|root,339FP@2|Bacteria,1NA60@1224|Proteobacteria,1SH3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158416_k127_1617908_17	58123.JOFJ01000003_gene1990	5.133e-175	560.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4EGGZ@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158416_k127_1617908_22	28444.JODQ01000016_gene7150	2.599e-156	504.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4EFKK@85012|Streptosporangiales	201174|Actinobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	rip1	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158416_k127_1617908_10	593907.Celgi_2087	4.525e-213	665.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4F1ZE@85016|Cellulomonadaceae	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158416_k127_1617908_40	67257.JODR01000008_gene3693	4.985e-102	344.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158416_k127_1617908_39	208439.AJAP_31415	1.817e-102	346.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4E0A0@85010|Pseudonocardiales	201174|Actinobacteria	M	Capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158416_k127_1617908_4	479431.Namu_2200	4.616e-284	898.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4ERXH@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158416_k127_1617908_8	1123023.JIAI01000002_gene5266	7.142e-235	736.0	COG1249@1|root,COG1249@2|Bacteria,2GPG1@201174|Actinobacteria,4DXK3@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_1617908_77	1123322.KB904681_gene4755	7.991e-31	126.0	2EA6A@1|root,334B4@2|Bacteria,2II4E@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4439
SRR25158416_k127_1617908_82	1236902.ANAS01000025_gene381	0.00026	51.0	2DXY1@1|root,3475T@2|Bacteria,2GQKV@201174|Actinobacteria,4EKP3@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158416_k127_1617908_63	1246448.ANAZ01000015_gene5969	8.932e-48	177.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,4EJF1@85012|Streptosporangiales	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158416_k127_1617908_19	1048339.KB913029_gene3563	2.198e-169	540.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4ERKN@85013|Frankiales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158416_k127_1617908_79	227882.SAV_2552	1.01e-23	104.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria	201174|Actinobacteria	K	nucleic-acid-binding protein implicated in transcription termination	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158416_k127_1617908_2	590998.Celf_1532	0.0	1099.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4F0Z9@85016|Cellulomonadaceae	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158416_k127_1617908_75	1236902.ANAS01000025_gene377	1.437e-33	132.0	COG1550@1|root,COG1550@2|Bacteria,2IQW4@201174|Actinobacteria,4EK9F@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158416_k127_1617908_59	67352.JODS01000037_gene6820	3.379e-57	204.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158416_k127_1617908_34	1120936.KB907220_gene2031	4.725e-110	368.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4EGVA@85012|Streptosporangiales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158416_k127_1617908_41	469371.Tbis_1066	8.789e-98	345.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4DZQA@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158416_k127_1617908_73	1120950.KB892747_gene3686	1.092e-37	144.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4DS16@85009|Propionibacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158416_k127_1617908_1	1054860.KB913030_gene4955	0.0	1147.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158416_k127_1617908_14	1120950.KB892747_gene3684	8.245e-186	592.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4DNY1@85009|Propionibacteriales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158416_k127_1617908_38	1089455.MOPEL_009_00490	9.591e-103	339.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4F6D8@85018|Dermatophilaceae	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158416_k127_1617908_67	479435.Kfla_2963	2.027e-43	172.0	COG0457@1|root,COG0457@2|Bacteria,2I2JF@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1617908_78	1120950.KB892747_gene3679	1.174e-26	115.0	2E45J@1|root,32Z1K@2|Bacteria,2GR89@201174|Actinobacteria,4DS7J@85009|Propionibacteriales	201174|Actinobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158416_k127_1617908_55	1120950.KB892747_gene3678	2.308e-61	224.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4DQH9@85009|Propionibacteriales	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158416_k127_1617908_48	298654.FraEuI1c_3898	1.057e-76	262.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,4EV7M@85013|Frankiales	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158416_k127_1617908_54	471853.Bcav_4211	4.465e-64	225.0	COG2411@1|root,COG2411@2|Bacteria,2IN3A@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1617908_57	1120950.KB892747_gene3676	7.771e-58	207.0	COG0454@1|root,COG0456@2|Bacteria,2I2XB@201174|Actinobacteria,4DQWV@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_1617908_50	1206741.BAFX01000007_gene5735	9.01e-76	260.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4FUFV@85025|Nocardiaceae	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158416_k127_1617908_16	1120950.KB892747_gene3674	2.337e-176	555.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4DNME@85009|Propionibacteriales	201174|Actinobacteria	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158416_k127_1617908_66	1121385.AQXW01000004_gene1532	6.192e-44	176.0	COG3460@1|root,COG3460@2|Bacteria,2IKMJ@201174|Actinobacteria,1ZWWJ@145357|Dermacoccaceae	201174|Actinobacteria	Q	Phenylacetic acid degradation B	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
SRR25158416_k127_1617908_37	479431.Namu_2489	9.34e-103	347.0	COG3396@1|root,COG3396@2|Bacteria,2GJIU@201174|Actinobacteria,4ERH2@85013|Frankiales	201174|Actinobacteria	S	PFAM phenylacetic acid catabolic family protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158416_k127_1617908_56	1416752.AYME01000004_gene2121	6.402e-58	211.0	COG2151@1|root,COG2151@2|Bacteria,2II4H@201174|Actinobacteria,4FNUZ@85023|Microbacteriaceae	201174|Actinobacteria	S	Iron-sulfur cluster assembly protein	paaJ	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158416_k127_1617908_25	1122138.AQUZ01000010_gene5127	1.224e-133	435.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4DNQQ@85009|Propionibacteriales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	paaK	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158416_k127_1617908_28	1120950.KB892747_gene3666	1.795e-122	399.0	COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2754c	Thy1
SRR25158416_k127_1617908_30	266940.Krad_1479	1.804e-119	391.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158416_k127_1617908_6	1463855.JOHV01000076_gene32	1.28e-264	827.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158416_k127_1617908_3	1033730.CAHG01000013_gene1415	0.0	1016.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4DN14@85009|Propionibacteriales	201174|Actinobacteria	D	Ftsk_gamma	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158416_k127_1617908_27	446466.Cfla_0086	4.375e-130	421.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158416_k127_1617908_15	110319.CF8_2448	6.829e-185	589.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,4DNHY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158416_k127_1617908_52	479435.Kfla_2994	8.424e-65	228.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4DQPW@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158416_k127_1617908_49	471852.Tcur_3304	6.513e-76	271.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4EJK6@85012|Streptosporangiales	201174|Actinobacteria	S	Competence-damaged protein	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158416_k127_1617908_76	1449347.JQLN01000005_gene3362	2.482e-31	128.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,2M314@2063|Kitasatospora	201174|Actinobacteria	K	Helix-turn-helix	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_1617908_0	1048339.KB913029_gene3595	0.0	2141.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4ES42@85013|Frankiales	201174|Actinobacteria	L	DEAD DEAH box helicase domain protein	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158416_k127_1617908_51	1394178.AWOO02000016_gene6941	1.936e-70	243.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4EP9Q@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR25158416_k127_1617908_83	68170.KL590511_gene2984	0.0003134	46.0	COG3576@1|root,COG3576@2|Bacteria,2I46F@201174|Actinobacteria,4EDRQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_1617908_65	1120950.KB892720_gene1813	3.007e-44	167.0	COG0262@1|root,COG0262@2|Bacteria,2IHZ7@201174|Actinobacteria,4DQPQ@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1617908_61	479431.Namu_2620	8.308e-54	193.0	COG0748@1|root,COG0748@2|Bacteria,2I6JE@201174|Actinobacteria	201174|Actinobacteria	P	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_1617908_12	1386089.N865_04695	3.755e-201	636.0	COG4191@1|root,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria,4FFVM@85021|Intrasporangiaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
SRR25158416_k127_1617908_5	1386089.N865_04690	5.465e-279	865.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4FFVK@85021|Intrasporangiaceae	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
SRR25158416_k127_1617908_80	1120950.KB892756_gene6693	7.624e-21	93.0	2AU8K@1|root,31JVT@2|Bacteria,2HZCZ@201174|Actinobacteria,4DS5N@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
SRR25158416_k127_1617908_20	1385519.N801_15195	2.817e-166	542.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158416_k127_1617908_70	710686.Mycsm_05707	4.913e-41	161.0	COG0745@1|root,COG0745@2|Bacteria,2HXJ4@201174|Actinobacteria,23DQ0@1762|Mycobacteriaceae	201174|Actinobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_1617908_21	1385519.N801_15185	3.796e-157	511.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,2GNPX@201174|Actinobacteria,4FFVN@85021|Intrasporangiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	osaB	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_1617908_24	318424.EU78_26750	1.793e-138	456.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,235H6@1762|Mycobacteriaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158416_k127_1617908_60	1385519.N801_15180	1.959e-55	196.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,4FK2A@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158416_k127_1617908_23	1304865.JAGF01000001_gene3757	4.536e-146	469.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158416_k127_1617908_46	1120950.KB892756_gene6690	1.299e-80	279.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4DQNH@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158416_k127_1617908_32	1304865.JAGF01000001_gene3755	1.068e-113	382.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158416_k127_1617908_35	367299.JOEE01000006_gene884	7.831e-108	370.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria,4FEDV@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158416_k127_1617908_64	1385519.N801_15195	2.485e-44	167.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158416_k127_1617908_11	1172188.KB911821_gene2078	1.906e-212	676.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158416_k127_1690811_3	1240349.ANGC01000049_gene3941	5.063e-91	311.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,4FWFR@85025|Nocardiaceae	201174|Actinobacteria	I	transferase	pcaJ2	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158416_k127_1690811_0	350054.Mflv_1349	1.912e-118	387.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,232EB@1762|Mycobacteriaceae	201174|Actinobacteria	I	transferase	scoA	-	2.8.3.5,2.8.3.6	ko:K01028,ko:K01031	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158416_k127_1690811_5	2002.JOEQ01000001_gene4769	2.368e-76	258.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4EJAM@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_1690811_2	1298863.AUEP01000008_gene1241	1.709e-95	321.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158416_k127_1690811_1	264198.Reut_B4129	2.272e-98	333.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,1K0IU@119060|Burkholderiaceae	28216|Betaproteobacteria	C	maleylacetate reductase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158416_k127_1690811_4	928724.SacglDRAFT_01423	5.871e-91	306.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4DZJ6@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	pcaR	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158416_k127_1690811_7	306281.AJLK01000102_gene3405	2.528e-54	196.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1690811_6	675635.Psed_4299	3.504e-72	246.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4DY3F@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Major Facilitator Superfamily	narK2	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,Sugar_tr
SRR25158416_k127_1692723_3	408672.NBCG_04773	3.015e-19	91.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	plcR	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158416_k127_1692723_1	1385519.N801_12275	9.289e-76	260.0	COG2350@1|root,COG2350@2|Bacteria,2HKSA@201174|Actinobacteria,4FHU5@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3,UPF0158
SRR25158416_k127_1692723_0	1108045.GORHZ_038_00240	5.464e-235	739.0	COG3057@1|root,COG3057@2|Bacteria,2I60V@201174|Actinobacteria	201174|Actinobacteria	L	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1692723_5	1331060.RLDS_24500	0.0004591	45.0	COG3609@1|root,COG3609@2|Bacteria,1N05M@1224|Proteobacteria,2UDPI@28211|Alphaproteobacteria,2K54D@204457|Sphingomonadales	28211|Alphaproteobacteria	K	CopG family transcripitonal regulator	-	-	-	-	-	-	-	-	-	-	-	-	ParD_antitoxin
SRR25158416_k127_1692723_2	935866.JAER01000015_gene1641	2.122e-28	116.0	COG3620@1|root,COG3620@2|Bacteria,2GX50@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158416_k127_1692723_4	313589.JNB_01010	1.497e-05	53.0	2F4PR@1|root,33XCU@2|Bacteria,2H49U@201174|Actinobacteria,4FJ16@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1693633_2	1120934.KB894403_gene393	3.947e-13	70.0	COG2346@1|root,COG2346@2|Bacteria,2I95U@201174|Actinobacteria,4ECXX@85010|Pseudonocardiales	201174|Actinobacteria	S	COG2346, Truncated hemoglobins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin,Fer4_19,zf-CDGSH
SRR25158416_k127_1693633_0	1121362.A605_03360	1.194e-117	387.0	COG0492@1|root,COG0492@2|Bacteria,2GIXN@201174|Actinobacteria,22MDZ@1653|Corynebacteriaceae	201174|Actinobacteria	C	Thioredoxin reductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158416_k127_1693633_1	408672.NBCG_03337	2.53e-36	143.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria,4DP0Q@85009|Propionibacteriales	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158416_k127_1693633_3	330084.JNYZ01000004_gene706	9.277e-05	45.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	3-HAO,Cupin_2
SRR25158416_k127_169364_0	1246995.AFR_09095	1.942e-118	396.0	COG4246@1|root,COG4246@2|Bacteria,2I2V1@201174|Actinobacteria	201174|Actinobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
SRR25158416_k127_1696599_0	479435.Kfla_1778	1.888e-212	668.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4DNVT@85009|Propionibacteriales	201174|Actinobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158416_k127_1696599_1	443255.SCLAV_p1180	8.836e-21	93.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria	201174|Actinobacteria	S	beta-lactamase domain protein	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158416_k127_1704271_1	469383.Cwoe_1296	7.1e-43	173.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4CRWF@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158416_k127_1704271_0	1157637.KB892114_gene4683	2.189e-56	209.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_1705307_5	1229780.BN381_80286	1.494e-05	50.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,3UWVZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_1705307_2	35754.JNYJ01000008_gene3156	8.591e-10	70.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
SRR25158416_k127_1705307_3	1380394.JADL01000001_gene2264	1.313e-09	60.0	COG3304@1|root,COG3304@2|Bacteria,1RA96@1224|Proteobacteria,2U742@28211|Alphaproteobacteria,2JT9U@204441|Rhodospirillales	204441|Rhodospirillales	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
SRR25158416_k127_1705307_0	590998.Celf_2687	1.716e-18	92.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4F193@85016|Cellulomonadaceae	201174|Actinobacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
SRR25158416_k127_1705307_1	546414.Deide_15500	2.513e-16	85.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	dhaA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Hemerythrin
SRR25158416_k127_1705307_4	1333998.M2A_0959	4.566e-09	59.0	COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,2TU6R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhaA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_1707885_1	1120949.KB903302_gene6497	7.054e-26	107.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4DB6R@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158416_k127_1707885_0	502025.Hoch_2800	1.003e-77	280.0	2CC51@1|root,2Z7IU@2|Bacteria,1MU2B@1224|Proteobacteria,43855@68525|delta/epsilon subdivisions,2X3F4@28221|Deltaproteobacteria,2YUXD@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
SRR25158416_k127_1707885_2	290397.Adeh_3862	1.761e-20	95.0	28HUD@1|root,2Z813@2|Bacteria,1QJT5@1224|Proteobacteria,4381H@68525|delta/epsilon subdivisions,2X3BK@28221|Deltaproteobacteria,2YVA0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2398
SRR25158416_k127_1712636_0	1449346.JQMO01000003_gene3531	9.959e-189	612.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,2M288@2063|Kitasatospora	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158416_k127_1712636_2	1120950.KB892769_gene5400	1.329e-49	196.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4DR0Z@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the P(II) protein family	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158416_k127_1712636_1	479435.Kfla_4781	3.709e-141	462.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DNW9@85009|Propionibacteriales	201174|Actinobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158416_k127_1712636_3	512565.AMIS_51480	1.93e-35	139.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4D8WV@85008|Micromonosporales	201174|Actinobacteria	M	Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158416_k127_1716956_0	543632.JOJL01000017_gene9902	2.139e-101	337.0	COG0500@1|root,COG2226@2|Bacteria,2I3SA@201174|Actinobacteria,4DMSZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158416_k127_1716956_1	1120950.KB892720_gene1810	1.091e-54	194.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4DR4F@85009|Propionibacteriales	201174|Actinobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158416_k127_1732491_3	1206739.BAGJ01000088_gene332	3.31e-24	109.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4FU2C@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158416_k127_1732491_4	1996.JOFO01000004_gene3464	2.358e-17	84.0	COG0662@1|root,COG0662@2|Bacteria,2IN75@201174|Actinobacteria,4EKN4@85012|Streptosporangiales	201174|Actinobacteria	G	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_1732491_0	190486.XAC2233	1.794e-54	198.0	COG1028@1|root,COG1028@2|Bacteria,1RA3U@1224|Proteobacteria,1RREY@1236|Gammaproteobacteria,1X6EF@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158416_k127_1732491_2	58123.JOFJ01000002_gene2417	1.374e-39	152.0	COG0346@1|root,COG0346@2|Bacteria,2IQ7F@201174|Actinobacteria,4EPG4@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_1732491_1	1206737.BAGF01000023_gene1122	4.699e-45	167.0	COG3631@1|root,COG3631@2|Bacteria,2INF0@201174|Actinobacteria,4G1ZW@85025|Nocardiaceae	201174|Actinobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1733412_0	1038859.AXAU01000016_gene6869	2.125e-176	564.0	COG0654@1|root,COG0654@2|Bacteria,1QWT3@1224|Proteobacteria,2U2GE@28211|Alphaproteobacteria,3JZXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158416_k127_1733412_1	1380356.JNIK01000017_gene2798	2.115e-131	437.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4ESTX@85013|Frankiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158416_k127_1752650_1	1380390.JIAT01000010_gene3580	1.548e-50	186.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4CRHD@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_1752650_0	1172181.KB911702_gene806	4.093e-95	325.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158416_k127_1752650_2	28444.JODQ01000006_gene365	1.583e-40	153.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria,4EK19@85012|Streptosporangiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158416_k127_175320_0	1385519.N801_12685	8.693e-185	584.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4FE57@85021|Intrasporangiaceae	201174|Actinobacteria	S	PA domain	-	-	3.4.11.15	ko:K01264	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28
SRR25158416_k127_175320_3	1464048.JNZS01000010_gene5386	4.855e-46	180.0	COG3801@1|root,COG3801@2|Bacteria,2IHP4@201174|Actinobacteria,4DDVV@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158416_k127_175320_8	211114.JOEF01000003_gene2880	3.704e-11	70.0	2F6Y6@1|root,33ZE7@2|Bacteria,2GRRX@201174|Actinobacteria,4E6NF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_175320_4	479431.Namu_0197	3.1e-20	98.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4EWM7@85013|Frankiales	201174|Actinobacteria	S	copper resistance protein	-	-	-	ko:K07156,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
SRR25158416_k127_175320_1	1120950.KB892748_gene3227	1.812e-149	498.0	COG3336@1|root,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4DPN3@85009|Propionibacteriales	201174|Actinobacteria	P	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	copD	GO:0008150,GO:0040007	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158416_k127_175320_7	1220583.GOACH_09_00110	1.002e-13	83.0	29XPH@1|root,30JF3@2|Bacteria,2GRCU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_175320_6	247156.NFA_15200	1.388e-15	79.0	2CIEV@1|root,30ANG@2|Bacteria,2GVCG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
SRR25158416_k127_175320_2	1038859.AXAU01000002_gene650	1.086e-46	175.0	COG1506@1|root,COG1506@2|Bacteria,1QU77@1224|Proteobacteria,2TWQ1@28211|Alphaproteobacteria,3JTXV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
SRR25158416_k127_1769592_0	479434.Sthe_1229	2.133e-178	574.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_1769592_3	1463861.JNXE01000002_gene6382	1.193e-125	406.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_1769592_2	1101188.KI912155_gene3064	5.621e-130	427.0	COG1028@1|root,COG1028@2|Bacteria,2HGC6@201174|Actinobacteria,1WCHS@1268|Micrococcaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_1769592_1	1463861.JNXE01000002_gene6383	5.878e-135	436.0	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_1775313_1	1068978.AMETH_1262	1.128e-65	234.0	COG2133@1|root,COG2133@2|Bacteria,2ID9F@201174|Actinobacteria	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158416_k127_1775313_2	1380370.JIBA01000011_gene3299	3.762e-46	169.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1775313_0	1122611.KB903952_gene6024	6.617e-133	424.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4EN2S@85012|Streptosporangiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
SRR25158416_k127_17870_0	1229780.BN381_80336	8.658e-127	435.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,3UWDH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158416_k127_1841382_2	1206737.BAGF01000023_gene1122	3.301e-36	144.0	COG3631@1|root,COG3631@2|Bacteria,2INF0@201174|Actinobacteria,4G1ZW@85025|Nocardiaceae	201174|Actinobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1841382_1	35754.JNYJ01000076_gene36	1.125e-47	177.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4DDBF@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158416_k127_1841382_3	1120949.KB903295_gene2321	3.292e-20	101.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158416_k127_1841382_0	1133850.SHJG_1298	2.54e-56	203.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158416_k127_1841601_4	235985.BBPN01000021_gene6266	1.888e-18	94.0	COG1277@1|root,COG1277@2|Bacteria,2IMF1@201174|Actinobacteria,2NEM2@228398|Streptacidiphilus	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158416_k127_1841601_3	1121946.AUAX01000008_gene7384	1.908e-93	315.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D9SZ@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_1841601_1	1123024.AUII01000003_gene3382	1.021e-106	352.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria,4DX3K@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158416_k127_1841601_2	2074.JNYD01000005_gene3152	7.844e-100	331.0	COG2129@1|root,COG2129@2|Bacteria,2ICBG@201174|Actinobacteria,4DYD7@85010|Pseudonocardiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_1841601_0	1298880.AUEV01000005_gene900	3.092e-215	676.0	COG3408@1|root,COG3408@2|Bacteria,2ICEJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1844115_0	675635.Psed_6417	0.0	1154.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4DX52@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158416_k127_1844115_2	675635.Psed_6418	4.215e-218	686.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4E2D5@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158416_k127_1844115_1	479431.Namu_1840	6.526e-279	869.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4ETT9@85013|Frankiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158416_k127_1844115_7	1454004.AW11_02082	6.669e-19	91.0	COG0738@1|root,COG0738@2|Bacteria,1P1TX@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_1844115_5	68199.JNZO01000015_gene3546	1.328e-81	281.0	COG2017@1|root,COG3265@1|root,COG2017@2|Bacteria,COG3265@2|Bacteria,2GJ0H@201174|Actinobacteria	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,SKI
SRR25158416_k127_1844115_4	469383.Cwoe_0605	4.135e-131	439.0	COG2909@1|root,COG2909@2|Bacteria,2HF4A@201174|Actinobacteria,4CSVM@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
SRR25158416_k127_1844115_6	1283283.ATXA01000008_gene3128	1.357e-20	100.0	COG2909@1|root,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,4ETWF@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158416_k127_1844115_3	1150398.JIBJ01000005_gene3112	7.001e-138	443.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR25158416_k127_1846052_7	290340.AAur_0972	1.374e-13	70.0	COG3409@1|root,COG3409@2|Bacteria,2IM37@201174|Actinobacteria,1WBE2@1268|Micrococcaceae	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1846052_6	1197706.AKKK01000006_gene1206	3.289e-40	154.0	COG3070@1|root,COG3070@2|Bacteria,2IRAD@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158416_k127_1846052_1	1120950.KB892747_gene3669	2.309e-146	482.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4DN1Z@85009|Propionibacteriales	201174|Actinobacteria	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158416_k127_1846052_2	502025.Hoch_2002	1.477e-86	299.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158416_k127_1846052_4	479434.Sthe_2777	1.12e-65	236.0	COG2080@1|root,COG2080@2|Bacteria,2GBCT@200795|Chloroflexi,27YT4@189775|Thermomicrobia	189775|Thermomicrobia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2_2
SRR25158416_k127_1846052_0	502025.Hoch_2000	0.0	1232.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRR25158416_k127_1846052_3	196162.Noca_0231	2.928e-72	254.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2IA9U@201174|Actinobacteria,4DUZB@85009|Propionibacteriales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158416_k127_1846052_5	1122138.AQUZ01000001_gene1772	3.582e-57	202.0	COG0346@1|root,COG0346@2|Bacteria,2IKRF@201174|Actinobacteria,4DRS4@85009|Propionibacteriales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1846052_8	710687.KI912270_gene3178	1.02e-05	49.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,237QK@1762|Mycobacteriaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	ko:K18372	ko00640,map00640	-	R10705	RC00460,RC00461	ko00000,ko00001,ko01000	-	-	-	Beta-lactamase
SRR25158416_k127_1850775_13	391037.Sare_1132	2.611e-37	151.0	COG3861@1|root,COG3861@2|Bacteria,2IQ4Y@201174|Actinobacteria,4DEHC@85008|Micromonosporales	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1850775_0	103733.JNYO01000044_gene6635	2.27e-268	850.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4DXAD@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158416_k127_1850775_6	351607.Acel_0140	3.078e-123	415.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4ESZ4@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_1850775_11	595593.JREV01000037_gene3664	7.873e-80	276.0	COG4760@1|root,COG4760@2|Bacteria,2GNCK@201174|Actinobacteria,1W8ZB@1268|Micrococcaceae	201174|Actinobacteria	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
SRR25158416_k127_1850775_14	1120950.KB892752_gene6190	1.196e-32	130.0	2E5A7@1|root,3302F@2|Bacteria,2IQ7Z@201174|Actinobacteria,4DVUC@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRR25158416_k127_1850775_2	1120950.KB892752_gene6192	3.93e-197	621.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DPEV@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_1850775_7	1123320.KB889574_gene5696	1.578e-100	340.0	COG2755@1|root,COG2755@2|Bacteria,2GMVS@201174|Actinobacteria	201174|Actinobacteria	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158416_k127_1850775_1	1120950.KB892752_gene6198	5.449e-227	710.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DP8H@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158416_k127_1850775_8	1120950.KB892763_gene5525	1.755e-90	307.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4DQ8G@85009|Propionibacteriales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158416_k127_1850775_10	1206737.BAGF01000049_gene2962	9.271e-84	289.0	COG0300@1|root,COG0300@2|Bacteria,2GJ1R@201174|Actinobacteria,4FYJX@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_1850775_5	1068980.ARVW01000001_gene6222	1.935e-151	496.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,4E9KK@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158416_k127_1850775_4	469371.Tbis_3117	8.933e-195	616.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DX61@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158416_k127_1850775_12	1449355.JQNR01000005_gene5020	7.133e-78	271.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_1850775_3	1120950.KB892763_gene5541	2.602e-196	627.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4DPYX@85009|Propionibacteriales	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_1850775_9	479435.Kfla_5627	8.904e-85	286.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DN8T@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158416_k127_185376_1	1123024.AUII01000052_gene3914	1.968e-07	55.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158416_k127_185376_0	502025.Hoch_0043	4.678e-72	257.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,42N6J@68525|delta/epsilon subdivisions,2WJ0W@28221|Deltaproteobacteria,2Z08Y@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_185778_1	1033730.CAHG01000016_gene542	2.938e-47	175.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria,4DNCX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_185778_0	1323361.JPOC01000040_gene4238	1.09e-189	613.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4G001@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_185778_4	66874.JOFS01000088_gene6606	0.000643	53.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158416_k127_185778_2	479431.Namu_2366	3.39e-38	152.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4ETBE@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_185778_3	1380390.JIAT01000011_gene2299	3.396e-06	49.0	COG3025@1|root,COG3025@2|Bacteria,2IN8R@201174|Actinobacteria,4CSIW@84995|Rubrobacteria	84995|Rubrobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1860498_12	1123024.AUII01000004_gene1702	1.663e-70	239.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4E0V5@85010|Pseudonocardiales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_1860498_20	269800.Tfu_2084	4.012e-27	121.0	2EGCD@1|root,33A46@2|Bacteria,2I14B@201174|Actinobacteria,4EKUH@85012|Streptosporangiales	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
SRR25158416_k127_1860498_22	1476876.JOJO01000016_gene6940	1.396e-24	113.0	2DQB3@1|root,335R8@2|Bacteria,2GMQW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,DUF4352
SRR25158416_k127_1860498_3	390989.JOEG01000003_gene4566	6.451e-171	542.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4DASI@85008|Micromonosporales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158416_k127_1860498_7	1304865.JAGF01000001_gene291	7.628e-135	447.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4F12D@85016|Cellulomonadaceae	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158416_k127_1860498_6	1120950.KB892823_gene547	1.766e-148	477.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4DP0N@85009|Propionibacteriales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158416_k127_1860498_4	1120950.KB892823_gene550	1.04e-158	510.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4DNJ0@85009|Propionibacteriales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158416_k127_1860498_19	479435.Kfla_0700	8.646e-30	123.0	2E5JX@1|root,330B5@2|Bacteria,2GRDA@201174|Actinobacteria,4DS5C@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
SRR25158416_k127_1860498_23	66875.JODY01000037_gene882	5.795e-19	92.0	COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158416_k127_1860498_8	1206726.BAFV01000022_gene1596	6.092e-119	396.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4FU1Y@85025|Nocardiaceae	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR25158416_k127_1860498_10	391037.Sare_2733	9.181e-102	341.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4DAIP@85008|Micromonosporales	201174|Actinobacteria	P	molybdate ABC transporter, inner membrane subunit	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR25158416_k127_1860498_14	526225.Gobs_4970	1.565e-64	235.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4ESN3@85013|Frankiales	201174|Actinobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158416_k127_1860498_17	298655.KI912266_gene5523	2.385e-44	167.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4ET46@85013|Frankiales	201174|Actinobacteria	H	DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR25158416_k127_1860498_18	263358.VAB18032_25240	2.665e-32	139.0	COG4758@1|root,COG4758@2|Bacteria,2GMRP@201174|Actinobacteria,4DM7C@85008|Micromonosporales	201174|Actinobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158416_k127_1860498_16	1120950.KB892709_gene4163	3.204e-47	178.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria,4DQZ7@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158416_k127_1860498_15	408672.NBCG_02481	2.195e-49	185.0	COG0421@1|root,COG0421@2|Bacteria,2I2TN@201174|Actinobacteria,4DRAK@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158416_k127_1860498_2	1394178.AWOO02000086_gene1031	1.787e-234	734.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4EHVK@85012|Streptosporangiales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158416_k127_1860498_1	1120950.KB892823_gene569	6.09e-235	735.0	COG1875@1|root,COG1875@2|Bacteria,2GK8U@201174|Actinobacteria,4DNRD@85009|Propionibacteriales	201174|Actinobacteria	T	phosphate starvation-inducible protein PhoH	phoH2	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
SRR25158416_k127_1860498_9	1193181.BN10_920054	6.264e-118	383.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4FFWU@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS1	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158416_k127_1860498_11	1120950.KB892779_gene981	3.983e-99	327.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DQ8R@85009|Propionibacteriales	201174|Actinobacteria	S	Haemolysin-III related	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158416_k127_1860498_0	471853.Bcav_3705	2.167e-290	910.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria	201174|Actinobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158416_k127_1860498_5	1120950.KB892763_gene5548	2.1e-152	488.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4DP8N@85009|Propionibacteriales	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158416_k127_1860498_24	396014.BF93_10780	3.479e-10	67.0	2DRBP@1|root,33B4I@2|Bacteria,2GX78@201174|Actinobacteria,4FD2Z@85020|Dermabacteraceae	201174|Actinobacteria	S	Domain of unknown function (DUF4307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4307
SRR25158416_k127_1860498_13	1120950.KB892763_gene5547	3.758e-70	246.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4DQI3@85009|Propionibacteriales	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158416_k127_1860498_21	1123024.AUII01000024_gene228	2.617e-25	112.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	ko:K21786	ko00333,ko01130,map00333,map01130	M00837,M00838	R11670	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25,Methyltransf_31
SRR25158416_k127_1864016_0	1172180.KB911783_gene2460	9.477e-108	359.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_1864016_3	1214101.BN159_5447	2.872e-10	68.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158416_k127_1864016_5	1278073.MYSTI_00323	3.76e-06	54.0	COG2076@1|root,COG2076@2|Bacteria,1RJKJ@1224|Proteobacteria,42T4Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	multidrug resistance protein	mdtJ	GO:0003674,GO:0005215,GO:0005326,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0008150,GO:0008324,GO:0008519,GO:0015075,GO:0015101,GO:0015199,GO:0015203,GO:0015220,GO:0015291,GO:0015297,GO:0015606,GO:0015651,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0015846,GO:0015848,GO:0015871,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031460,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072349,GO:0072488,GO:0098655,GO:1902047,GO:1903711	-	ko:K03297,ko:K11743	-	M00711	-	-	ko00000,ko00002,ko02000	2.A.7.1,2.A.7.1.9	-	iAPECO1_1312.APECO1_683,iB21_1397.B21_01559,iBWG_1329.BWG_1415,iEC042_1314.EC042_1748,iEC55989_1330.EC55989_1765,iECBD_1354.ECBD_2046,iECB_1328.ECB_01569,iECDH10B_1368.ECDH10B_1733,iECDH1ME8569_1439.ECDH1ME8569_1543,iECD_1391.ECD_01569,iECED1_1282.ECED1_1769,iECH74115_1262.ECH74115_2310,iECIAI1_1343.ECIAI1_1650,iECNA114_1301.ECNA114_1647,iECO111_1330.ECO111_2069,iECO26_1355.ECO26_2304,iECOK1_1307.ECOK1_1718,iECP_1309.ECP_1544,iECS88_1305.ECS88_1645,iECSE_1348.ECSE_1721,iECSF_1327.ECSF_1460,iECSP_1301.ECSP_2164,iECW_1372.ECW_m1765,iECs_1301.ECs2306,iEKO11_1354.EKO11_2178,iETEC_1333.ETEC_1634,iEcDH1_1363.EcDH1_2043,iEcE24377_1341.EcE24377A_1807,iEcHS_1320.EcHS_A1674,iEcSMS35_1347.EcSMS35_1599,iEcolC_1368.EcolC_2030,iG2583_1286.G2583_1994,iJO1366.b1600,iLF82_1304.LF82_1301,iNRG857_1313.NRG857_08015,iSBO_1134.SBO_1536,iSDY_1059.SDY_1553,iSFV_1184.SFV_1615,iSF_1195.SF1621,iSFxv_1172.SFxv_1817,iSSON_1240.SSON_1560,iS_1188.S1753,iSbBS512_1146.SbBS512_E1786,iUMN146_1321.UM146_09165,iUMNK88_1353.UMNK88_2059,iUTI89_1310.UTI89_C1788,iWFL_1372.ECW_m1765,iY75_1357.Y75_RS08390,iZ_1308.Z2594	Multi_Drug_Res
SRR25158416_k127_1864016_4	263358.VAB18032_28931	1.202e-08	59.0	COG0582@1|root,COG2188@1|root,COG0582@2|Bacteria,COG2188@2|Bacteria,2I9QS@201174|Actinobacteria,4DC0Q@85008|Micromonosporales	201174|Actinobacteria	K	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158416_k127_1864016_2	1449044.JMLE01000009_gene3175	5.34e-19	97.0	COG0599@1|root,COG0599@2|Bacteria,2H7S5@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1864016_1	33876.JNXY01000043_gene3767	5.689e-68	240.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4DICY@85008|Micromonosporales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Reductase_C
SRR25158416_k127_1866509_10	298653.Franean1_4042	1.025e-84	280.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria,4EUQ9@85013|Frankiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_1866509_3	1120950.KB892720_gene1922	2.455e-146	475.0	COG2890@1|root,COG2890@2|Bacteria,2I3KM@201174|Actinobacteria,4DNZ4@85009|Propionibacteriales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
SRR25158416_k127_1866509_2	1120950.KB892775_gene1212	3.733e-149	477.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DPHB@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	eryBII	-	-	ko:K13315	ko00523,ko01130,map00523,map01130	M00798,M00799	R11051,R11474	RC00897,RC01516	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SRR25158416_k127_1866509_15	100226.SCO4338	2.135e-42	163.0	COG1514@1|root,COG1514@2|Bacteria,2GNDN@201174|Actinobacteria	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158416_k127_1866509_13	446470.Snas_5850	1.538e-50	190.0	COG3154@1|root,COG3154@2|Bacteria,2INVN@201174|Actinobacteria,4EYS1@85014|Glycomycetales	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158416_k127_1866509_4	110319.CF8_0661	2.035e-129	432.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4DNW0@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	pimH	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158416_k127_1866509_14	365528.KB891230_gene1928	1.446e-43	163.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4ET3M@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158416_k127_1866509_17	1122609.AUGT01000009_gene3378	1.702e-16	93.0	2ETMT@1|root,33M5J@2|Bacteria,2IQ41@201174|Actinobacteria,4DS24@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2530)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2530
SRR25158416_k127_1866509_6	263358.VAB18032_10265	6.141e-95	319.0	28KEA@1|root,2ZA0J@2|Bacteria,2I9YN@201174|Actinobacteria,4DCRZ@85008|Micromonosporales	201174|Actinobacteria	H	Sulfotransferase domain	-	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
SRR25158416_k127_1866509_0	1133850.SHJG_4789	2.005e-235	762.0	COG3225@1|root,COG3225@2|Bacteria,2GMTX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1866509_8	58123.JOFJ01000004_gene1909	1.599e-87	305.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4EHCS@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
SRR25158416_k127_1866509_5	1120950.KB892775_gene1195	6.873e-121	406.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4DNAP@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_1866509_12	351607.Acel_0104	2.219e-58	204.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4ESU8@85013|Frankiales	201174|Actinobacteria	K	PFAM Cold-shock protein, DNA-binding	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158416_k127_1866509_7	591167.Sfla_5515	1.341e-89	301.0	COG1718@1|root,COG1718@2|Bacteria,2GKX1@201174|Actinobacteria	201174|Actinobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1866509_16	452652.KSE_70550	2.431e-39	157.0	2CP0Z@1|root,32SI8@2|Bacteria,2IHXV@201174|Actinobacteria,2M39I@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158416_k127_1866509_1	1120950.KB892775_gene1193	8.205e-169	543.0	COG0546@1|root,COG1606@1|root,COG0546@2|Bacteria,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria,4DP0G@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,HAD,HAD_2,Hydrolase_like,NAD_synthase,QueC
SRR25158416_k127_1866509_11	1095767.CAHD01000130_gene1287	8.775e-73	263.0	COG1404@1|root,COG1404@2|Bacteria,2GNIX@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158416_k127_1866509_9	263358.VAB18032_25015	1.002e-85	301.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4DI6E@85008|Micromonosporales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158416_k127_1868961_1	469383.Cwoe_5366	3.608e-29	117.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CPPG@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_1868961_0	1370125.AUWT01000029_gene668	5.657e-144	467.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,239R6@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,LZ_Tnp_IS481,rve,rve_3
SRR25158416_k127_1869536_0	35754.JNYJ01000071_gene4227	6.354e-133	430.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4DBQA@85008|Micromonosporales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158416_k127_1869536_1	446465.Bfae_27530	1.806e-92	316.0	COG1752@1|root,COG1752@2|Bacteria,2IA6V@201174|Actinobacteria,4FC03@85020|Dermabacteraceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158416_k127_1869536_2	477641.MODMU_4215	1.19e-32	129.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,2I2E0@201174|Actinobacteria,4ESXB@85013|Frankiales	201174|Actinobacteria	Q	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
SRR25158416_k127_1874795_0	1121924.ATWH01000023_gene3221	4.759e-50	182.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4FNDS@85023|Microbacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158416_k127_1874795_3	1122138.AQUZ01000016_gene286	8.431e-11	72.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR25158416_k127_1874795_2	749414.SBI_00806	1.242e-23	102.0	COG1879@1|root,COG1879@2|Bacteria,2GN16@201174|Actinobacteria	201174|Actinobacteria	K	LacI family transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
SRR25158416_k127_1889143_0	330084.JNYZ01000043_gene1545	1.978e-191	612.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,4E0HE@85010|Pseudonocardiales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158416_k127_1889143_3	330084.JNYZ01000043_gene1546	5.039e-93	321.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4E1MA@85010|Pseudonocardiales	201174|Actinobacteria	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158416_k127_1889143_8	561175.KB894093_gene2714	3.051e-21	103.0	COG1073@1|root,COG1073@2|Bacteria,2I364@201174|Actinobacteria,4EMRI@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_1889143_9	869210.Marky_1921	1.45e-17	92.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158416_k127_1889143_2	517418.Ctha_0976	2.583e-118	394.0	COG0667@1|root,COG0667@2|Bacteria,1FEFR@1090|Chlorobi	1090|Chlorobi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_1889143_1	479434.Sthe_1229	2.138e-158	519.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_1889143_7	675635.Psed_4350	2.178e-29	127.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_1889143_5	1214101.BN159_4301	1.31e-50	200.0	COG1595@1|root,COG1595@2|Bacteria,2H45C@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_1889143_10	1122138.AQUZ01000019_gene8183	5.639e-16	85.0	2DGEZ@1|root,2ZVQ5@2|Bacteria,2GYKS@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_1889143_4	1122138.AQUZ01000019_gene8184	6.038e-84	286.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DNPK@85009|Propionibacteriales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158416_k127_1889818_16	405948.SACE_3043	0.0002741	50.0	2E4RI@1|root,32ZK2@2|Bacteria,2GTNG@201174|Actinobacteria,4E6M9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1889818_5	1048339.KB913029_gene4390	1.083e-52	198.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1889818_0	1476583.DEIPH_ctg139orf0070	1.657e-188	605.0	COG0737@1|root,COG0737@2|Bacteria,1WI46@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
SRR25158416_k127_1889818_12	1089544.KB912942_gene2650	1.68e-23	108.0	COG3462@1|root,COG3462@2|Bacteria,2GWIQ@201174|Actinobacteria,4E7IH@85010|Pseudonocardiales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158416_k127_1889818_15	110319.CF8_4087	1.219e-11	72.0	28JCJ@1|root,2Z977@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR25158416_k127_1889818_10	110319.CF8_4087	1.883e-28	117.0	28JCJ@1|root,2Z977@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR25158416_k127_1889818_3	246196.MSMEI_5732	6.394e-96	317.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,234RT@1762|Mycobacteriaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_29,HTH_32
SRR25158416_k127_1889818_8	1206729.BAFZ01000155_gene5838	4.474e-42	165.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4FUCZ@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_1889818_11	1082933.MEA186_09605	8.565e-27	120.0	COG2346@1|root,COG2346@2|Bacteria,1Q38S@1224|Proteobacteria,2UJT6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158416_k127_1889818_14	557599.MKAN_21860	2.546e-13	72.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,234F2@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_1889818_4	1111729.ATYV01000011_gene310	1.3e-53	193.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,22K9X@1653|Corynebacteriaceae	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
SRR25158416_k127_1889818_6	649831.L083_3869	5.859e-50	186.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_18
SRR25158416_k127_1889818_9	649743.HMPREF0972_01874	1.798e-40	156.0	COG0645@1|root,COG0645@2|Bacteria,2IKMM@201174|Actinobacteria,4D38D@85005|Actinomycetales	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158416_k127_1889818_7	196162.Noca_2178	4.341e-49	178.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4DRY6@85009|Propionibacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_1889818_2	105422.BBPM01000066_gene480	1.376e-96	321.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria,2NH67@228398|Streptacidiphilus	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_1889818_13	1996.JOFO01000002_gene5571	9.274e-15	84.0	COG1309@1|root,COG1309@2|Bacteria,2GMZ1@201174|Actinobacteria,4ENXJ@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_1889818_1	491916.RHECIAT_CH0000465	2.042e-124	416.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TUPK@28211|Alphaproteobacteria,4BDDQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	ix monomethyl ester oxidative cyclase	bchE	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
SRR25158416_k127_1901360_0	1229780.BN381_80336	9.49e-58	222.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,3UWDH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158416_k127_1904055_22	1120950.KB892801_gene1794	1.845e-111	370.0	COG1171@1|root,COG1171@2|Bacteria,2I8UC@201174|Actinobacteria,4DR0H@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_1904055_50	1134445.AJJM01000064_gene1806	8.442e-22	101.0	2EGDD@1|root,33A58@2|Bacteria,2GR3X@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRR25158416_k127_1904055_37	68219.JNXI01000032_gene7044	2.254e-76	270.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria	201174|Actinobacteria	O	cytochrome C	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158416_k127_1904055_8	1120950.KB892801_gene1786	3.899e-177	578.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4DN12@85009|Propionibacteriales	201174|Actinobacteria	O	ResB-like family	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158416_k127_1904055_32	1906.SFRA_25305	4.984e-94	317.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158416_k127_1904055_44	1120950.KB892801_gene1784	4.636e-48	179.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4DRF7@85009|Propionibacteriales	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158416_k127_1904055_35	1120950.KB892801_gene1783	4.157e-85	292.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4DPM9@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158416_k127_1904055_7	1120950.KB892801_gene1782	1.439e-185	591.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4DNRS@85009|Propionibacteriales	201174|Actinobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158416_k127_1904055_54	469371.Tbis_1699	2.271e-16	83.0	2E89B@1|root,332N6@2|Bacteria,2IMU0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1904055_25	710685.MycrhN_2451	1.346e-108	381.0	COG0657@1|root,COG0657@2|Bacteria,2I3E3@201174|Actinobacteria,23FE4@1762|Mycobacteriaceae	201174|Actinobacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1904055_39	479435.Kfla_0243	1.926e-71	251.0	COG3103@1|root,COG3103@2|Bacteria,2I3RJ@201174|Actinobacteria,4DR7V@85009|Propionibacteriales	201174|Actinobacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
SRR25158416_k127_1904055_56	479432.Sros_9330	3.781e-06	49.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4EHIR@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_1904055_34	1464048.JNZS01000006_gene4077	3.168e-86	306.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4DB02@85008|Micromonosporales	201174|Actinobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1904055_1	479432.Sros_3413	3.225e-236	750.0	COG0421@1|root,COG0421@2|Bacteria,2I3HX@201174|Actinobacteria,4EHKS@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158416_k127_1904055_43	208439.AJAP_35405	8.199e-54	191.0	COG0500@1|root,COG4911@1|root,COG2226@2|Bacteria,COG4911@2|Bacteria,2IGSQ@201174|Actinobacteria,4E511@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203,Methyltransf_11,Methyltransf_25
SRR25158416_k127_1904055_46	35754.JNYJ01000055_gene9994	4.112e-33	132.0	COG0662@1|root,COG0662@2|Bacteria,2II1B@201174|Actinobacteria,4DDJ1@85008|Micromonosporales	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_1904055_11	1136417.AZWE01000015_gene1513	5.488e-152	485.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4D999@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158416_k127_1904055_4	196162.Noca_0496	1.912e-210	668.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4DNP0@85009|Propionibacteriales	201174|Actinobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158416_k127_1904055_19	1380356.JNIK01000018_gene734	1.909e-116	382.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4ES8B@85013|Frankiales	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
SRR25158416_k127_1904055_12	1463887.KL589994_gene7809	6.678e-140	460.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158416_k127_1904055_29	58344.JOEL01000064_gene5406	2.966e-99	331.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158416_k127_1904055_38	1122247.C731_0658	5.787e-75	262.0	COG2822@1|root,COG2822@2|Bacteria,2GJPY@201174|Actinobacteria,235KZ@1762|Mycobacteriaceae	201174|Actinobacteria	P	periplasmic lipoprotein involved in iron transport	efeO	-	-	ko:K07224	-	-	-	-	ko00000,ko02000	2.A.108.2.3	-	-	Cupredoxin_1,Peptidase_M75
SRR25158416_k127_1904055_16	1150599.MPHLEI_06137	7.497e-126	419.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,232Z9@1762|Mycobacteriaceae	201174|Actinobacteria	P	Dyp-type peroxidase family	efeB	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox,TAT_signal
SRR25158416_k127_1904055_48	1172188.KB911826_gene47	3.067e-29	119.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria,4FHMF@85021|Intrasporangiaceae	201174|Actinobacteria	O	Glutaredoxin-like domain (DUF836)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158416_k127_1904055_30	1157637.KB892096_gene897	9.888e-99	333.0	COG0560@1|root,COG0560@2|Bacteria,2GJW9@201174|Actinobacteria	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	serB1	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158416_k127_1904055_14	67352.JODS01000008_gene7249	6.681e-136	445.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158416_k127_1904055_13	1120950.KB892801_gene1769	4.981e-139	449.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DPEE@85009|Propionibacteriales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
SRR25158416_k127_1904055_49	1394178.AWOO02000038_gene9074	2.71e-25	106.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,4EKJX@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_1904055_10	479435.Kfla_6393	2.024e-170	543.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4DN6Q@85009|Propionibacteriales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158416_k127_1904055_45	1120950.KB892801_gene1765	2.945e-40	157.0	COG0454@1|root,COG0456@2|Bacteria,2GQGN@201174|Actinobacteria,4DS9Y@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_1904055_18	479435.Kfla_6400	2e-119	400.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4DNEJ@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158416_k127_1904055_17	1386089.N865_08765	4.111e-124	404.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4FEKP@85021|Intrasporangiaceae	201174|Actinobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158416_k127_1904055_36	1385518.N798_13705	1.116e-84	287.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria,4FF6C@85021|Intrasporangiaceae	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_1904055_33	479435.Kfla_6404	7.273e-90	303.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4DQ62@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_1904055_42	1944.JOAZ01000022_gene3228	1.109e-55	203.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,4184J@629295|Streptomyces griseus group	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_1904055_23	455632.SGR_4133	7.67e-111	367.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4183P@629295|Streptomyces griseus group	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158416_k127_1904055_26	479435.Kfla_6408	4.985e-106	349.0	28IRH@1|root,2Z8QX@2|Bacteria,2GJW6@201174|Actinobacteria,4DP80@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_1904055_6	1120950.KB892801_gene1750	3.137e-189	601.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DNF3@85009|Propionibacteriales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158416_k127_1904055_9	1120950.KB892801_gene1748	2.075e-172	548.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4DNMZ@85009|Propionibacteriales	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR25158416_k127_1904055_21	1894.JOER01000009_gene8128	4.365e-115	383.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria	201174|Actinobacteria	L	adenine glycosylase	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158416_k127_1904055_51	345341.KUTG_04395	2.095e-20	95.0	COG0457@1|root,COG0457@2|Bacteria,2I3MN@201174|Actinobacteria,4E4BA@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158416_k127_1904055_0	105422.BBPM01000008_gene6389	0.0	1433.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,2NHD1@228398|Streptacidiphilus	201174|Actinobacteria	O	Bacterial TniB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158416_k127_1904055_47	1394178.AWOO02000023_gene5523	1.046e-32	130.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,4EJZY@85012|Streptosporangiales	201174|Actinobacteria	S	Lsr2	-	-	-	-	-	-	-	-	-	-	-	-	Lsr2
SRR25158416_k127_1904055_40	1120936.KB907215_gene4219	3.637e-70	242.0	COG1246@1|root,COG1246@2|Bacteria,2GJBT@201174|Actinobacteria,4EI9U@85012|Streptosporangiales	201174|Actinobacteria	E	Acetyltransferase (GNAT) family	argA	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158416_k127_1904055_5	1120950.KB892801_gene1742	1.143e-204	654.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4DNHS@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158416_k127_1904055_20	1003195.SCAT_2626	2.425e-116	381.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158416_k127_1904055_28	351607.Acel_0214	6.157e-102	340.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4ESAD@85013|Frankiales	201174|Actinobacteria	H	PFAM Quinolinate phosphoribosyl transferase	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158416_k127_1904055_2	1123320.KB889585_gene1808	2.776e-225	711.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158416_k127_1904055_31	1120949.KB903306_gene7657	1.738e-97	327.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4D99B@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158416_k127_1904055_24	1123320.KB889585_gene1805	1.115e-110	366.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158416_k127_1904055_27	1120950.KB892801_gene1730	1.035e-105	353.0	COG1565@1|root,COG1565@2|Bacteria,2GKIU@201174|Actinobacteria,4DTE5@85009|Propionibacteriales	201174|Actinobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158416_k127_1904055_15	1120950.KB892801_gene1729	4.039e-127	421.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4DQ4J@85009|Propionibacteriales	201174|Actinobacteria	S	overlaps another CDS with the same product name	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158416_k127_1904055_41	1120950.KB892801_gene1727	1.549e-57	209.0	COG3402@1|root,COG3402@2|Bacteria,2IR88@201174|Actinobacteria,4DRVV@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158416_k127_1904055_3	1120950.KB892801_gene1726	1.203e-215	677.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DSY9@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the complex I 49 kDa subunit family	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158416_k127_1904055_53	1120950.KB892746_gene3588	1.149e-16	91.0	2B5Z6@1|root,31YVD@2|Bacteria,2H1B0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158416_k127_1912565_4	1385519.N801_15195	1.04e-30	124.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158416_k127_1912565_3	1380386.JIAW01000006_gene1202	1.588e-43	168.0	COG0745@1|root,COG0745@2|Bacteria,2HXJ4@201174|Actinobacteria,23DQ0@1762|Mycobacteriaceae	201174|Actinobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_1912565_0	351607.Acel_1492	6.636e-190	597.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4ERDP@85013|Frankiales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158416_k127_1912565_2	58123.JOFJ01000023_gene3551	5.695e-56	201.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4EJ6Q@85012|Streptosporangiales	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158416_k127_1912565_1	1394178.AWOO02000010_gene4120	7.211e-186	593.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4EG5E@85012|Streptosporangiales	201174|Actinobacteria	V	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158416_k127_1916406_3	1283283.ATXA01000003_gene1646	3.669e-43	165.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,4EVJY@85013|Frankiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_1916406_4	479431.Namu_2023	2.53e-32	134.0	2DW3A@1|root,33YCP@2|Bacteria,2GZ8M@201174|Actinobacteria,4EVKN@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158416_k127_1916406_2	1380390.JIAT01000010_gene4390	3.887e-67	244.0	COG2931@1|root,COG2931@2|Bacteria,2GYC8@201174|Actinobacteria	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158416_k127_1916406_0	1122611.KB903952_gene6025	1.699e-180	568.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4EG3V@85012|Streptosporangiales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158416_k127_1916406_1	1122611.KB903952_gene6024	7.382e-109	354.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4EN2S@85012|Streptosporangiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
SRR25158416_k127_1923610_4	935840.JAEQ01000015_gene3711	7.482e-07	53.0	COG1073@1|root,COG1073@2|Bacteria,1MVAA@1224|Proteobacteria,2U0SU@28211|Alphaproteobacteria,43PYB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
SRR25158416_k127_1923610_2	1408418.JNJH01000068_gene1661	3.117e-25	109.0	COG1073@1|root,COG1073@2|Bacteria,1MVAA@1224|Proteobacteria,2U0SU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
SRR25158416_k127_1923610_1	35754.JNYJ01000021_gene388	3.98e-46	171.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4DETT@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1923610_0	101510.RHA1_ro04229	1.094e-184	582.0	COG3547@1|root,COG3547@2|Bacteria,2HASG@201174|Actinobacteria,4FY46@85025|Nocardiaceae	201174|Actinobacteria	L	Protein involved in DNA binding, transposase activity and DNA transposition	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_1923610_3	313589.JNB_01200	2.534e-12	68.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4FF88@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_1942494_4	1172188.KB911831_gene4000	1.096e-33	133.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria,4FGRZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158416_k127_1942494_0	356851.JOAN01000019_gene4397	5.199e-260	809.0	COG3333@1|root,COG3333@2|Bacteria,2GJB2@201174|Actinobacteria,4DA21@85008|Micromonosporales	201174|Actinobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
SRR25158416_k127_1942494_3	356851.JOAN01000019_gene4396	7.336e-56	198.0	2D22U@1|root,3160H@2|Bacteria,2H7EW@201174|Actinobacteria	201174|Actinobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
SRR25158416_k127_1942494_1	356851.JOAN01000019_gene4395	3.873e-154	493.0	COG3181@1|root,COG3181@2|Bacteria,2I3SR@201174|Actinobacteria,4DFFQ@85008|Micromonosporales	201174|Actinobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158416_k127_1942494_5	471852.Tcur_2353	2.195e-14	77.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_1942494_2	512565.AMIS_24930	1.345e-67	237.0	COG3832@1|root,COG3832@2|Bacteria,2IFJT@201174|Actinobacteria,4DEVF@85008|Micromonosporales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_194381_2	1120950.KB892830_gene5042	6.547e-60	214.0	COG4346@1|root,COG4346@2|Bacteria,2GITT@201174|Actinobacteria,4DWGK@85009|Propionibacteriales	201174|Actinobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	pmt	GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
SRR25158416_k127_194381_1	67267.JNXT01000044_gene5327	2.178e-105	349.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158416_k127_194381_0	1121877.JQKF01000013_gene252	3.078e-147	477.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CMP6@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158416_k127_1975938_1	235985.BBPN01000003_gene4735	1.219e-71	258.0	COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2GJ21@201174|Actinobacteria,2NGBT@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158416_k127_1975938_0	219305.MCAG_00294	1.104e-124	417.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,LRR_5,Laminin_G_3
SRR25158416_k127_1991307_4	1386089.N865_21270	5.934e-17	85.0	COG2181@1|root,COG2181@2|Bacteria,2GJVI@201174|Actinobacteria,4FFNE@85021|Intrasporangiaceae	201174|Actinobacteria	C	Nitrate reductase	narI	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482	1.7.5.1	ko:K00370,ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iNJ661.Rv1164	Nitrate_red_gam
SRR25158416_k127_1991307_3	675635.Psed_4302	7.666e-71	248.0	COG2180@1|root,COG2180@2|Bacteria,2IM8P@201174|Actinobacteria,4EEZN@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitrate reductase delta subunit	narJ	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
SRR25158416_k127_1991307_1	1123024.AUII01000046_gene3923	9.928e-312	968.0	COG1140@1|root,COG1140@2|Bacteria,2GJ8P@201174|Actinobacteria,4DYH1@85010|Pseudonocardiales	201174|Actinobacteria	C	Nitrate reductase beta subunit	narH	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
SRR25158416_k127_1991307_0	2074.JNYD01000002_gene5542	0.0	2113.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4DZ13@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008940,GO:0009056,GO:0009628,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016491,GO:0016661,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036293,GO:0036294,GO:0042126,GO:0042128,GO:0042221,GO:0042493,GO:0043436,GO:0043602,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070482,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071453,GO:0071704,GO:0071731,GO:0071732,GO:0071941,GO:0071944,GO:0097366,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:2001057	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
SRR25158416_k127_1991307_2	675635.Psed_4299	7.708e-101	335.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4DY3F@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Major Facilitator Superfamily	narK2	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,Sugar_tr
SRR25158416_k127_1991307_5	675635.Psed_4299	4.21e-13	70.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4DY3F@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Major Facilitator Superfamily	narK2	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,Sugar_tr
SRR25158416_k127_200383_2	1386089.N865_14320	1.771e-67	236.0	COG2755@1|root,COG2755@2|Bacteria,2GMDE@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
SRR25158416_k127_200383_1	1386089.N865_19290	3.059e-69	241.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria,4FIIB@85021|Intrasporangiaceae	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158416_k127_200383_3	47716.JOFH01000015_gene5648	3.621e-41	156.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158416_k127_200383_0	479434.Sthe_2971	1.029e-70	252.0	COG2267@1|root,COG2267@2|Bacteria,2G6MI@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_200383_4	358823.DF19_01725	2.412e-39	151.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_200383_5	1449058.JQKT01000007_gene761	5.463e-06	53.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FNJ1@85023|Microbacteriaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_2005244_5	1120950.KB892709_gene4087	1.218e-110	367.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DQ8U@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_2005244_3	1120950.KB892743_gene3143	2.195e-162	524.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4DN0D@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158416_k127_2005244_17	234267.Acid_7087	2.343e-07	56.0	COG1680@1|root,COG1680@2|Bacteria,3Y6F4@57723|Acidobacteria	57723|Acidobacteria	V	PFAM Beta-lactamase	-	-	3.4.16.4	ko:K18988	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase,DUF3471
SRR25158416_k127_2005244_18	1968.JOEV01000031_gene8168	1.68e-05	47.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158416_k127_2005244_0	246196.MSMEI_5010	3.016e-203	646.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,235G0@1762|Mycobacteriaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158416_k127_2005244_8	357808.RoseRS_3434	1.189e-101	344.0	COG0667@1|root,COG0667@2|Bacteria,2G889@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SRR25158416_k127_2005244_13	926569.ANT_09520	2.112e-32	135.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158416_k127_2005244_12	208444.JNYY01000001_gene5330	1.29e-33	136.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4DYUT@85010|Pseudonocardiales	201174|Actinobacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158416_k127_2005244_16	749927.AMED_4597	1.793e-08	59.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4DYUT@85010|Pseudonocardiales	201174|Actinobacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158416_k127_2005244_7	67356.KL575629_gene1824	7.419e-104	357.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_2005244_6	105422.BBPM01000005_gene6051	3.431e-104	347.0	COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,2NM7Q@228398|Streptacidiphilus	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_2005244_4	749414.SBI_06428	5.231e-128	426.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
SRR25158416_k127_2005244_15	749414.SBI_06429	2.08e-10	63.0	COG1874@1|root,COG1874@2|Bacteria,2GK4P@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRR25158416_k127_2005244_11	448385.sce3317	3.893e-53	194.0	COG1609@1|root,COG1609@2|Bacteria,1MVZ4@1224|Proteobacteria,43B20@68525|delta/epsilon subdivisions,2X6G2@28221|Deltaproteobacteria,2YYW1@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn _helix lactose operon repressor	lacI2	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_2005244_2	471857.Svir_23450	9.236e-166	530.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4E0K4@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158416_k127_2005244_1	285535.JOEY01000035_gene3716	1.127e-170	544.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158416_k127_2005244_14	33898.JRHJ01000055_gene5857	2.545e-26	113.0	COG1874@1|root,COG1874@2|Bacteria,2GK4P@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRR25158416_k127_2005244_10	1288079.AUKN01000005_gene4623	3.082e-65	236.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158416_k127_2005244_9	66869.JNXG01000004_gene2480	2.837e-69	240.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,419Q2@629295|Streptomyces griseus group	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158416_k127_2008671_6	1304865.JAGF01000001_gene2013	1.559e-101	342.0	COG1132@1|root,COG1132@2|Bacteria,2GJ8B@201174|Actinobacteria,4F11Y@85016|Cellulomonadaceae	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_2008671_1	1380370.JIBA01000016_gene775	1.617e-193	621.0	COG1132@1|root,COG1132@2|Bacteria,2GJAP@201174|Actinobacteria,4FF0Q@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_2008671_0	1298863.AUEP01000003_gene2930	3.66e-263	820.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4DPFU@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158416_k127_2008671_4	928724.SacglDRAFT_04228	6.83e-103	347.0	COG0584@1|root,COG0584@2|Bacteria,2GM8K@201174|Actinobacteria,4DX6D@85010|Pseudonocardiales	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158416_k127_2008671_7	1048339.KB913029_gene2814	3.215e-53	205.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4EW85@85013|Frankiales	201174|Actinobacteria	KT	PFAM PspC domain protein	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
SRR25158416_k127_2008671_2	1120950.KB892783_gene321	8.719e-121	407.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DNII@85009|Propionibacteriales	201174|Actinobacteria	T	PspC domain	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
SRR25158416_k127_2008671_5	1120950.KB892783_gene320	6.059e-102	335.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4DQ1R@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_2008671_9	479435.Kfla_1240	8.694e-30	122.0	2E4PN@1|root,32ZIA@2|Bacteria,2HZDV@201174|Actinobacteria,4DSB1@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2008671_8	1385519.N801_04640	4.637e-31	125.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4FE57@85021|Intrasporangiaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158416_k127_2008671_3	1304865.JAGF01000001_gene2956	3.296e-118	390.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4F2MZ@85016|Cellulomonadaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_2008671_10	419947.MRA_1593	0.0002758	45.0	COG3378@1|root,COG3378@2|Bacteria,2H1DT@201174|Actinobacteria,2395B@1762|Mycobacteriaceae	201174|Actinobacteria	L	D5 N terminal like	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
SRR25158416_k127_2032164_4	2074.JNYD01000046_gene7323	9.106e-05	46.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria,4E5XH@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158416_k127_2032164_2	1122609.AUGT01000006_gene1498	8.06e-21	95.0	COG2155@1|root,COG2155@2|Bacteria,2H8ZK@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF378)	-	-	-	-	-	-	-	-	-	-	-	-	DUF378
SRR25158416_k127_2032164_1	543632.JOJL01000035_gene5070	4.245e-102	341.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158416_k127_2032164_0	1463926.JOCA01000014_gene775	5.949e-242	756.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria	201174|Actinobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158416_k127_2032164_3	525909.Afer_0265	2.081e-09	59.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4CNB8@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_2055468_2	479432.Sros_3490	8.91e-147	471.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EH24@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158416_k127_2055468_3	1380393.JHVP01000003_gene1247	6.073e-141	460.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4EU93@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_2055468_5	1245475.ANAE01000128_gene4759	5.817e-128	415.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria,4EJFT@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	smoG	-	-	ko:K02026,ko:K10229	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
SRR25158416_k127_2055468_4	882083.SacmaDRAFT_4650	2.944e-137	442.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,4DZMV@85010|Pseudonocardiales	201174|Actinobacteria	G	Permease component of ABC-type sugar transporter	smoF	-	-	ko:K02025,ko:K10228	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
SRR25158416_k127_2055468_0	882083.SacmaDRAFT_4651	1.843e-222	697.0	COG1653@1|root,COG1653@2|Bacteria,2GNI2@201174|Actinobacteria,4DYB3@85010|Pseudonocardiales	201174|Actinobacteria	G	ABC-type sugar transport system, periplasmic component	smoE	-	-	ko:K02027,ko:K10227	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	SBP_bac_1
SRR25158416_k127_2055468_14	446468.Ndas_3997	2.397e-76	269.0	COG2390@1|root,COG2390@2|Bacteria,2GMIM@201174|Actinobacteria,4EKN6@85012|Streptosporangiales	201174|Actinobacteria	K	Putative sugar-binding domain	-	-	-	ko:K11531	ko02024,ko02026,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sugar-bind
SRR25158416_k127_2055468_24	1403819.BATR01000092_gene2782	1.787e-07	63.0	COG2103@1|root,COG2971@1|root,COG2103@2|Bacteria,COG2971@2|Bacteria,46SJI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,SIS_2
SRR25158416_k127_2055468_12	685727.REQ_07780	1.597e-98	331.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4FWYQ@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_2055468_7	471852.Tcur_0579	6.15e-117	401.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4EHHW@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158416_k127_2055468_22	1394178.AWOO02000082_gene2166	2.409e-08	61.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
SRR25158416_k127_2055468_19	35754.JNYJ01000001_gene7303	1.51e-22	108.0	COG0508@1|root,COG0508@2|Bacteria,2GQQK@201174|Actinobacteria,4DFUH@85008|Micromonosporales	201174|Actinobacteria	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2055468_16	35754.JNYJ01000001_gene7302	5.536e-60	214.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4DDU9@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2055468_1	263358.VAB18032_23085	2.625e-157	506.0	COG2850@1|root,COG2850@2|Bacteria,2GMR2@201174|Actinobacteria,4D9R8@85008|Micromonosporales	201174|Actinobacteria	S	transcription factor jumonji jmjC	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158416_k127_2055468_21	1150864.MILUP08_43310	1.594e-08	59.0	2C2Y4@1|root,333DJ@2|Bacteria,2IQWE@201174|Actinobacteria,4DM9W@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2055468_6	1463825.JNXC01000023_gene4915	4.233e-125	408.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DZQX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_2055468_9	263358.VAB18032_06520	7.941e-113	372.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DA4V@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158416_k127_2055468_10	469371.Tbis_2338	3.031e-103	344.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4DXG0@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase D DNA polymerase LigD	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158416_k127_2055468_17	479435.Kfla_1859	7.496e-50	179.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4DR8F@85009|Propionibacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158416_k127_2055468_23	397278.JOJN01000007_gene3106	3.619e-08	60.0	2DYK7@1|root,34A68@2|Bacteria,2HZGV@201174|Actinobacteria,4DSRQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158416_k127_2055468_8	58123.JOFJ01000012_gene5311	3.248e-114	379.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4EFVM@85012|Streptosporangiales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SRR25158416_k127_2055468_13	1463900.JOIX01000115_gene4108	1.799e-90	306.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt ABC transporter	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SRR25158416_k127_2055468_11	479435.Kfla_3569	5.832e-99	338.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria,4DNYF@85009|Propionibacteriales	201174|Actinobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158416_k127_2055468_15	1246995.AFR_06475	4.363e-65	237.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4D9TD@85008|Micromonosporales	201174|Actinobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158416_k127_2055468_18	935839.JAGJ01000020_gene89	7.104e-27	121.0	2EGCD@1|root,33A46@2|Bacteria,2I0MJ@201174|Actinobacteria,4F4SW@85017|Promicromonosporaceae	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
SRR25158416_k127_2055468_25	711393.AYRX01000101_gene5844	2.176e-05	55.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
SRR25158416_k127_2055468_20	1385521.N803_04250	9.761e-10	65.0	2DN77@1|root,32VXJ@2|Bacteria,2GXBC@201174|Actinobacteria,4FIGA@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_206171_7	471852.Tcur_1954	7.752e-87	293.0	COG3315@1|root,COG3315@2|Bacteria,2GJIS@201174|Actinobacteria,4ENAN@85012|Streptosporangiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158416_k127_206171_3	391037.Sare_2232	6.509e-140	449.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4D8TS@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_206171_8	35754.JNYJ01000021_gene426	7.812e-31	123.0	2E6IT@1|root,3315W@2|Bacteria,2GR2R@201174|Actinobacteria,4DFKV@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR25158416_k127_206171_6	28042.GU90_05785	3.322e-89	306.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4DX8T@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158416_k127_206171_5	994479.GL877879_gene6216	2.698e-93	320.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4DYFK@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158416_k127_206171_0	471852.Tcur_2404	1.224e-168	533.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4EI6I@85012|Streptosporangiales	201174|Actinobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158416_k127_206171_4	593907.Celgi_0730	6.342e-118	391.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4F0IF@85016|Cellulomonadaceae	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
SRR25158416_k127_206171_2	882083.SacmaDRAFT_0555	1.161e-151	497.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4DYET@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158416_k127_206171_1	479435.Kfla_6301	1.023e-151	486.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4DPGF@85009|Propionibacteriales	201174|Actinobacteria	HQ	Isochorismate synthase	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158416_k127_2077675_1	500153.JOEK01000001_gene3659	9.415e-53	190.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158416_k127_2077675_2	500153.JOEK01000001_gene3658	4.501e-46	177.0	COG4977@1|root,COG4977@2|Bacteria,2IJTB@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158416_k127_2077675_0	211165.AJLN01000134_gene5782	2.538e-174	556.0	COG0076@1|root,COG0076@2|Bacteria,1GD62@1117|Cyanobacteria,1JME6@1189|Stigonemataceae	1117|Cyanobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158416_k127_208641_1	675635.Psed_6779	5.213e-63	231.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4E984@85010|Pseudonocardiales	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR25158416_k127_208641_0	426117.M446_2801	1.621e-207	657.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,1JVDJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158416_k127_208740_20	1120950.KB892707_gene4875	4.272e-45	168.0	COG2227@1|root,COG2227@2|Bacteria,2GMAR@201174|Actinobacteria,4DQJ6@85009|Propionibacteriales	201174|Actinobacteria	H	Methyltransferase domain	smtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158416_k127_208740_23	1048339.KB913029_gene4589	1.16e-31	134.0	2E49S@1|root,32RRE@2|Bacteria,2I83P@201174|Actinobacteria,4ETFD@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRR25158416_k127_208740_7	1120950.KB892707_gene4877	2.843e-144	490.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4DNMN@85009|Propionibacteriales	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158416_k127_208740_13	1120950.KB892707_gene4878	2.143e-122	406.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4DNDP@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158416_k127_208740_9	1120950.KB892707_gene4879	1.022e-141	456.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DNSG@85009|Propionibacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158416_k127_208740_16	1120950.KB892707_gene4880	1.458e-63	228.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4DQJP@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158416_k127_208740_11	1120950.KB892707_gene4882	5.595e-133	434.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4DPXU@85009|Propionibacteriales	201174|Actinobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158416_k127_208740_25	1120950.KB892707_gene4883	2.254e-20	95.0	COG2919@1|root,COG2919@2|Bacteria,2GTFA@201174|Actinobacteria,4DX0A@85009|Propionibacteriales	201174|Actinobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_208740_8	1120950.KB892707_gene4884	3.312e-144	481.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4DNVU@85009|Propionibacteriales	201174|Actinobacteria	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158416_k127_208740_5	1463895.JODA01000021_gene7472	1.456e-166	538.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria	201174|Actinobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_208740_4	1463887.KL590001_gene5542	2.939e-172	552.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	GO:0008150,GO:0040007	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_208740_6	367299.JOEE01000004_gene1359	2.847e-157	503.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4FEX5@85021|Intrasporangiaceae	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158416_k127_208740_1	1120950.KB892707_gene4888	1.285e-194	635.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4DNTV@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_208740_12	1120950.KB892707_gene4889	3.767e-126	418.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4DNHR@85009|Propionibacteriales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
SRR25158416_k127_208740_10	1463900.JOIX01000040_gene2895	4.609e-139	451.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158416_k127_208740_2	479435.Kfla_2887	2.884e-189	608.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4DNNN@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_208740_22	1122994.AUFR01000028_gene57	4.977e-32	138.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4DRPK@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158416_k127_208740_3	68194.JNXR01000012_gene6124	5.217e-180	571.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158416_k127_208740_15	749414.SBI_07882	3.508e-74	258.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158416_k127_208740_14	1394178.AWOO02000032_gene4871	3.403e-78	268.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4EGGM@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158416_k127_208740_17	1205910.B005_3804	4.08e-56	203.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4EIJC@85012|Streptosporangiales	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158416_k127_208740_18	1906.SFRA_02190	8.229e-50	181.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158416_k127_208740_24	1454010.JEOE01000006_gene2106	3.351e-27	116.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4F1J0@85016|Cellulomonadaceae	201174|Actinobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158416_k127_208740_19	1048339.KB913029_gene4569	5.068e-49	184.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4ET2B@85013|Frankiales	201174|Actinobacteria	D	PFAM DivIVA family protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158416_k127_208740_0	390989.JOEG01000001_gene5328	0.0	1552.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4D973@85008|Micromonosporales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158416_k127_208740_21	350054.Mflv_0099	2.141e-41	153.0	2EHMU@1|root,33BDI@2|Bacteria,2GQGA@201174|Actinobacteria,23A1Q@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
SRR25158416_k127_2093724_0	526226.Gbro_2670	1.894e-121	398.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria,4GFWP@85026|Gordoniaceae	201174|Actinobacteria	L	integrase domain protein SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_2093724_1	479431.Namu_2521	1.209e-100	337.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_2093724_4	1160137.KB907308_gene6412	1.223e-10	71.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria,4G2D9@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158416_k127_2093724_3	2002.JOEQ01000012_gene5766	4.342e-63	219.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria,4EP0W@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158416_k127_2093724_2	485913.Krac_2756	4.808e-65	225.0	COG1028@1|root,COG1028@2|Bacteria	485913.Krac_2756|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2098084_2	298655.KI912266_gene3131	8.185e-12	66.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4ERIY@85013|Frankiales	201174|Actinobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158416_k127_2098084_0	1032480.MLP_35430	1.744e-159	512.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DPNR@85009|Propionibacteriales	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158416_k127_2098084_1	196162.Noca_4911	1.034e-49	177.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DPV2@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_2105288_2	1157634.KB912987_gene3646	9.942e-05	49.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158416_k127_2105288_0	314264.ROS217_23107	8.027e-11	65.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,46RE2@74030|Roseovarius	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	CAP,HCBP_related,HemolysinCabind
SRR25158416_k127_2105576_14	526225.Gobs_2177	8.254e-125	411.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4EWFM@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	nylB	-	3.5.1.46	ko:K01453	ko00930,ko01120,map00930,map01120	-	R00059,R10975,R10979	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	Beta-lactamase
SRR25158416_k127_2105576_10	1122138.AQUZ01000066_gene4339	2.416e-134	444.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158416_k127_2105576_18	1123023.JIAI01000008_gene1266	2.819e-88	296.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4E8J0@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_2105576_8	446470.Snas_3339	8.023e-163	526.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_2105576_17	1193181.BN10_690004	4.41e-104	344.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FFNS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_2105576_0	313589.JNB_08544	5.977e-254	797.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FE6A@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158416_k127_2105576_25	446466.Cfla_1494	5.069e-65	225.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158416_k127_2105576_3	1386089.N865_10005	6.161e-211	661.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria,4FFH8@85021|Intrasporangiaceae	201174|Actinobacteria	E	COG1748 Saccharopine dehydrogenase and related	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158416_k127_2105576_12	35754.JNYJ01000008_gene3159	5.894e-131	425.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4D9QG@85008|Micromonosporales	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158416_k127_2105576_11	479435.Kfla_3500	2.484e-134	442.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DPDF@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_2105576_22	1206725.BAFU01000058_gene820	3.611e-73	252.0	COG0412@1|root,COG0412@2|Bacteria,2I37P@201174|Actinobacteria,4G9XT@85025|Nocardiaceae	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158416_k127_2105576_9	1120950.KB892775_gene1207	1.331e-158	516.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4DNF2@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	1.8.3.1	ko:K00387	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00533	RC00168	ko00000,ko00001,ko01000	-	-	-	Oxidored_molyb
SRR25158416_k127_2105576_21	1068978.AMETH_1424	3.517e-73	253.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4E0TE@85010|Pseudonocardiales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158416_k127_2105576_16	479435.Kfla_1847	2.482e-113	377.0	COG2123@1|root,COG2123@2|Bacteria,2I466@201174|Actinobacteria,4DX26@85009|Propionibacteriales	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158416_k127_2105576_20	1449353.JQMQ01000005_gene4006	2.97e-82	289.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,2NERP@228398|Streptacidiphilus	201174|Actinobacteria	S	Beta-lactamase superfamily domain	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158416_k127_2105576_15	1380347.JNII01000006_gene1973	8.644e-119	387.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4ERE1@85013|Frankiales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158416_k127_2105576_31	1380347.JNII01000005_gene3697	4.447e-40	164.0	2AR9G@1|root,31GJC@2|Bacteria,2GN9V@201174|Actinobacteria,4EWX7@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4192
SRR25158416_k127_2105576_34	196162.Noca_0955	1.785e-11	71.0	2C2HM@1|root,333M3@2|Bacteria,2GR8S@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2695
SRR25158416_k127_2105576_7	479432.Sros_1728	2.599e-165	524.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4EHYN@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158416_k127_2105576_32	1003195.SCAT_1942	2.267e-39	149.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria	201174|Actinobacteria	H	PFAM thiamineS protein	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158416_k127_2105576_26	446468.Ndas_0381	6.643e-65	226.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4EJ5N@85012|Streptosporangiales	201174|Actinobacteria	S	JAB/MPN domain	mec	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158416_k127_2105576_29	397278.JOJN01000007_gene3127	5.355e-44	168.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4DQGY@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158416_k127_2105576_30	1120950.KB892709_gene4055	2.991e-43	161.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4DRQZ@85009|Propionibacteriales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158416_k127_2105576_5	1274.HX89_09915	3.938e-180	576.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,1ZVG5@145357|Dermacoccaceae	201174|Actinobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
SRR25158416_k127_2105576_19	1120950.KB892709_gene4053	1.34e-84	284.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4DQD6@85009|Propionibacteriales	201174|Actinobacteria	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158416_k127_2105576_1	405948.SACE_3944	1.462e-228	711.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,4DXK4@85010|Pseudonocardiales	201174|Actinobacteria	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158416_k127_2105576_24	1120950.KB892751_gene6798	5.651e-69	244.0	COG0124@1|root,COG0124@2|Bacteria,2GJXW@201174|Actinobacteria,4DQBI@85009|Propionibacteriales	201174|Actinobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2105576_6	66377.JOBH01000020_gene4267	2.291e-174	555.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria	201174|Actinobacteria	Q	Fumarylacetoacetase	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158416_k127_2105576_4	1122138.AQUZ01000009_gene4050	3.769e-189	603.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4DPR6@85009|Propionibacteriales	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158416_k127_2105576_2	211114.JOEF01000002_gene4451	8.514e-217	679.0	COG3185@1|root,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria,4DX4C@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	hpd	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158416_k127_2105576_27	479433.Caci_1485	2.42e-53	194.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria	201174|Actinobacteria	K	asnC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158416_k127_2105576_36	110319.CF8_3492	7.123e-08	61.0	2F1E7@1|root,33UEX@2|Bacteria,2GUBT@201174|Actinobacteria,4DSFZ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR25158416_k127_2105576_23	1223523.H340_23883	5.158e-71	245.0	COG1414@1|root,COG1414@2|Bacteria,2GMEA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	sdrB	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158416_k127_2105576_28	396014.BF93_07820	1.241e-51	186.0	COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4FCVC@85020|Dermabacteraceae	201174|Actinobacteria	O	Thioredoxin	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158416_k127_2105576_13	1463887.KL590019_gene8037	3.197e-127	422.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_2105576_33	1120950.KB892751_gene6774	1.179e-36	143.0	2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4DRHQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
SRR25158416_k127_2108009_0	710696.Intca_1216	7.189e-119	385.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,4FETB@85021|Intrasporangiaceae	201174|Actinobacteria	F	pyrimidine-nucleoside phosphorylase	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158416_k127_2108009_1	1123024.AUII01000046_gene3934	1.318e-89	304.0	COG2267@1|root,COG2267@2|Bacteria,2I1RU@201174|Actinobacteria,4E1FR@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_2108009_2	1303692.SFUL_5634	3.457e-69	238.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_211535_1	1440053.JOEI01000001_gene1664	4.238e-170	538.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158416_k127_211535_5	446469.Sked_37320	0.0001959	47.0	COG0609@1|root,COG0609@2|Bacteria,2GJB9@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158416_k127_211535_4	1297570.MESS4_360144	0.0001056	46.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,2U9TG@28211|Alphaproteobacteria,43MEK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_211535_0	749414.SBI_01563	1.141e-223	699.0	COG0477@1|root,COG2814@2|Bacteria,2HU7R@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158416_k127_211535_3	928724.SacglDRAFT_03223	2.52e-76	266.0	COG0346@1|root,COG0346@2|Bacteria,2IHYP@201174|Actinobacteria,4E3KN@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_211535_2	1123024.AUII01000048_gene808	1.419e-77	261.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4E2S3@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158416_k127_2126913_17	1120949.KB903358_gene5060	2.786e-55	213.0	2DF6G@1|root,2ZQMZ@2|Bacteria,2HDJU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2126913_8	1120949.KB903358_gene5059	1.409e-149	497.0	2C1VD@1|root,33TWV@2|Bacteria,2H4GJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2126913_22	1120946.AUBF01000006_gene405	1.201e-11	67.0	2EGRW@1|root,33AI2@2|Bacteria,2IQF3@201174|Actinobacteria,4D63W@85005|Actinomycetales	201174|Actinobacteria	S	Protein of unknown function (DUF3073)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3073
SRR25158416_k127_2126913_6	928724.SacglDRAFT_03203	2.39e-160	518.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4DYKG@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	vdh	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.4.1.23	ko:K00271	ko00280,ko01100,ko01110,ko01130,map00280,map01100,map01110,map01130	-	R01212,R01434	RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158416_k127_2126913_20	1123322.KB904713_gene5267	4.869e-30	122.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria	201174|Actinobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_2126913_21	1449355.JQNR01000005_gene5898	3.081e-12	77.0	2ESVE@1|root,33KDT@2|Bacteria,2I8VG@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158416_k127_2126913_23	1449355.JQNR01000005_gene5899	1.339e-08	65.0	299G0@1|root,2ZWIS@2|Bacteria,2IGC2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2126913_10	105422.BBPM01000029_gene3840	2.021e-142	462.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,2NF5X@228398|Streptacidiphilus	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR3	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158416_k127_2126913_13	1120950.KB892753_gene6092	1.555e-98	336.0	COG1721@1|root,COG1721@2|Bacteria,2I9E2@201174|Actinobacteria,4DQW5@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158416_k127_2126913_18	561175.KB894098_gene5285	6.291e-55	204.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158416_k127_2126913_25	1298860.AUEM01000002_gene721	3.312e-06	54.0	2DMKA@1|root,32S5N@2|Bacteria,2GYRE@201174|Actinobacteria	201174|Actinobacteria	S	SPW repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPW
SRR25158416_k127_2126913_5	1123023.JIAI01000013_gene3898	1.659e-161	532.0	COG4266@1|root,COG4266@2|Bacteria,2GJ1V@201174|Actinobacteria,4DXW3@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
SRR25158416_k127_2126913_9	469371.Tbis_2591	2.524e-145	470.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4DXZB@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158416_k127_2126913_3	479432.Sros_4856	2.38e-220	690.0	COG0044@1|root,COG0044@2|Bacteria,2IAM1@201174|Actinobacteria,4EGI4@85012|Streptosporangiales	201174|Actinobacteria	F	Amidohydrolase family	allB	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158416_k127_2126913_0	1380386.JIAW01000003_gene637	1.6e-322	994.0	COG3960@1|root,COG3960@2|Bacteria,2GJY3@201174|Actinobacteria,237T8@1762|Mycobacteriaceae	201174|Actinobacteria	S	Thiamine pyrophosphate enzyme, central domain	gcl	-	4.1.1.47	ko:K01608	ko00630,ko01100,map00630,map01100	-	R00013	RC00899	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158416_k127_2126913_12	1445613.JALM01000009_gene676	1.781e-122	405.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4E1KD@85010|Pseudonocardiales	201174|Actinobacteria	I	2-hydroxy-3-oxopropionate reductase	garR	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158416_k127_2126913_11	526225.Gobs_2842	4.187e-128	425.0	COG3622@1|root,COG3622@2|Bacteria,2GKPC@201174|Actinobacteria,4EUF6@85013|Frankiales	201174|Actinobacteria	H	PFAM Xylose isomerase domain protein TIM barrel	hyi	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_2126913_4	882082.SaccyDRAFT_2604	5.347e-162	520.0	COG2301@1|root,COG2301@2|Bacteria,2GNNK@201174|Actinobacteria,4E0B4@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158416_k127_2126913_2	1120950.KB892768_gene5278	1.351e-270	841.0	COG2225@1|root,COG2225@2|Bacteria,2GJGP@201174|Actinobacteria,4DNPW@85009|Propionibacteriales	201174|Actinobacteria	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158416_k127_2126913_14	446468.Ndas_0712	1.072e-81	287.0	COG1414@1|root,COG1414@2|Bacteria,2GJUA@201174|Actinobacteria,4EH88@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	iclR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158416_k127_2126913_19	994479.GL877883_gene7552	7.283e-37	143.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4E5V4@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158416_k127_2126913_7	479431.Namu_0250	1.832e-150	480.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria,4ETS9@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	-	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRR25158416_k127_2126913_15	1313172.YM304_25320	1.03e-76	265.0	COG4630@1|root,COG4630@2|Bacteria,2I33J@201174|Actinobacteria	201174|Actinobacteria	F	Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
SRR25158416_k127_2126913_16	1157637.KB892155_gene7699	9.287e-56	210.0	COG2080@1|root,COG2080@2|Bacteria,2GMXT@201174|Actinobacteria	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158416_k127_2126913_1	35754.JNYJ01000021_gene505	1.218e-280	885.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4D96N@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158416_k127_2126913_24	1463885.KL578448_gene9344	6.143e-07	52.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria	201174|Actinobacteria	F	Xanthine uracil	pbuX	-	-	-	-	-	-	-	-	-	-	-	OHCU_decarbox,Xan_ur_permease
SRR25158416_k127_2167660_3	1298863.AUEP01000006_gene3325	1.83e-22	100.0	COG0702@1|root,COG0702@2|Bacteria,2HM0I@201174|Actinobacteria,4DSP9@85009|Propionibacteriales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158416_k127_2167660_1	1077972.ARGLB_114_00090	2.178e-120	388.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,1WA4A@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_2167660_0	1123023.JIAI01000007_gene1713	1.656e-144	462.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4E0YK@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158416_k127_2167660_2	1463917.JODC01000001_gene489	2.019e-30	120.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2183378_0	743718.Isova_0816	7.843e-234	745.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4F5DF@85017|Promicromonosporaceae	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158416_k127_2183378_1	2074.JNYD01000023_gene1296	8.385e-111	378.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DXGE@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158416_k127_2186462_6	1120950.KB892780_gene400	1.078e-18	85.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158416_k127_2186462_8	1283283.ATXA01000047_gene4040	1.555e-10	70.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_38,rve
SRR25158416_k127_2186462_1	1123023.JIAI01000001_gene6028	1.466e-79	268.0	COG3871@1|root,COG3871@2|Bacteria,2I3KD@201174|Actinobacteria,4E3CA@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_2186462_7	1068980.ARVW01000001_gene1073	1.189e-10	72.0	COG3903@1|root,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR25158416_k127_2186462_4	436229.JOEH01000009_gene4358	4.713e-35	142.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,2NEV0@228398|Streptacidiphilus	201174|Actinobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
SRR25158416_k127_2186462_2	1150399.AQYK01000001_gene1288	1.179e-69	246.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FN63@85023|Microbacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,NB-ARC,TPR_12
SRR25158416_k127_2186462_9	1198449.ACAM_1394	0.000776	48.0	COG3427@1|root,arCOG01927@2157|Archaea,2XRD9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158416_k127_2186462_10	926564.KI911609_gene4317	0.0008862	50.0	COG1595@1|root,COG1595@2|Bacteria,2GNBE@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_2186462_3	926564.KI911644_gene2463	3.569e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,2GNBE@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_2186462_0	100226.SCO7627	1.846e-87	294.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria	201174|Actinobacteria	H	reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_2186462_5	36809.MAB_3370	4.831e-31	124.0	COG1687@1|root,COG1687@2|Bacteria,2GRID@201174|Actinobacteria,23AAD@1762|Mycobacteriaceae	201174|Actinobacteria	E	branched-chain amino acid	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158416_k127_2200819_14	1121946.AUAX01000019_gene7885	1.286e-07	56.0	COG1112@1|root,COG1198@1|root,COG2852@1|root,COG1112@2|Bacteria,COG1198@2|Bacteria,COG2852@2|Bacteria,2GKJW@201174|Actinobacteria,4DBGN@85008|Micromonosporales	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
SRR25158416_k127_2200819_9	1304865.JAGF01000001_gene388	6.916e-37	143.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4F2NC@85016|Cellulomonadaceae	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158416_k127_2200819_7	1122138.AQUZ01000078_gene6113	2.373e-50	186.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria,4DW8U@85009|Propionibacteriales	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158416_k127_2200819_10	1120950.KB892750_gene6876	1.62e-35	143.0	COG3745@1|root,COG3745@2|Bacteria,2GQJH@201174|Actinobacteria,4DS59@85009|Propionibacteriales	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,RcpC,SAF
SRR25158416_k127_2200819_12	351607.Acel_0161	3.519e-25	108.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4ET9G@85013|Frankiales	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158416_k127_2200819_0	397278.JOJN01000011_gene1592	1.276e-299	942.0	COG2366@1|root,COG2366@2|Bacteria,2GISQ@201174|Actinobacteria,4DPIK@85009|Propionibacteriales	201174|Actinobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158416_k127_2200819_11	1095767.CAHD01000136_gene2302	1.745e-35	143.0	2AWFS@1|root,31NC1@2|Bacteria,2IMS0@201174|Actinobacteria,4F1EB@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2200819_6	1120950.KB892750_gene6887	1.091e-55	202.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4DR3Y@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158416_k127_2200819_2	653045.Strvi_1101	2.117e-136	440.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria	201174|Actinobacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158416_k127_2200819_1	351607.Acel_0167	8.776e-152	492.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4ERWC@85013|Frankiales	201174|Actinobacteria	H	MoeA domain protein domain I and II	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158416_k127_2200819_4	1172181.KB911707_gene2251	5.748e-64	238.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158416_k127_2200819_5	266940.Krad_3686	5.288e-62	221.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria	201174|Actinobacteria	H	Molybdenum cofactor synthesis	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
SRR25158416_k127_2200819_3	1134445.AJJM01000022_gene4238	1.621e-77	269.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria	201174|Actinobacteria	J	N-acetyltransferase	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158416_k127_2200819_13	452652.KSE_45900	4.448e-23	109.0	2ETNC@1|root,33M63@2|Bacteria,2GKI3@201174|Actinobacteria,2M2MU@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2200819_16	1288083.AUKR01000009_gene1877	0.0002543	44.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158416_k127_2200819_15	935866.JAER01000027_gene4230	5.323e-06	51.0	COG0457@1|root,COG0457@2|Bacteria,2I3MN@201174|Actinobacteria,4DSSI@85009|Propionibacteriales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158416_k127_2200819_8	1394178.AWOO02000096_gene8209	6.62e-44	164.0	COG0748@1|root,COG0748@2|Bacteria,2INF5@201174|Actinobacteria	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_2202194_0	1380356.JNIK01000017_gene2999	1.406e-224	705.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4EUGZ@85013|Frankiales	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158416_k127_2202194_5	313589.JNB_10359	9.039e-147	474.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4FEAN@85021|Intrasporangiaceae	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158416_k127_2202194_4	1385518.N798_02065	1.791e-147	492.0	COG1879@1|root,COG1879@2|Bacteria,2GJ0Z@201174|Actinobacteria,4FE7I@85021|Intrasporangiaceae	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158416_k127_2202194_2	1380356.JNIK01000017_gene2996	5.371e-196	617.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4ESXV@85013|Frankiales	201174|Actinobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_2202194_1	1146883.BLASA_3621	2.412e-209	659.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4EREZ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_2202194_8	471857.Svir_11080	1.2e-99	331.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4E1CS@85010|Pseudonocardiales	201174|Actinobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
SRR25158416_k127_2202194_3	1463845.JOIG01000005_gene3258	4.427e-161	516.0	COG1260@1|root,COG1260@2|Bacteria,2GJVN@201174|Actinobacteria	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SRR25158416_k127_2202194_7	43354.JOIJ01000008_gene2973	8.799e-100	333.0	COG0382@1|root,COG0382@2|Bacteria,2GK6R@201174|Actinobacteria,4E46Q@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158416_k127_2202194_6	1236902.ANAS01000020_gene1603	1.879e-109	374.0	COG1082@1|root,COG1082@2|Bacteria,2GK34@201174|Actinobacteria,4EIT8@85012|Streptosporangiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	AP_endonuc_2
SRR25158416_k127_2202194_10	43354.JOIJ01000008_gene2975	3.081e-54	206.0	COG1082@1|root,COG1082@2|Bacteria,2I94T@201174|Actinobacteria,4E5YR@85010|Pseudonocardiales	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2202194_9	935866.JAER01000017_gene4400	7.948e-69	234.0	COG1099@1|root,COG1099@2|Bacteria,2GIUY@201174|Actinobacteria,4DU80@85009|Propionibacteriales	201174|Actinobacteria	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
SRR25158416_k127_2226148_0	1184607.AUCHE_05_00880	3.71e-48	188.0	COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,4F7VK@85018|Dermatophilaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_2228678_4	1389489.O159_20470	1.164e-73	255.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4FP8Q@85023|Microbacteriaceae	201174|Actinobacteria	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158416_k127_2228678_2	66897.DJ64_22960	3.233e-94	319.0	COG0673@1|root,COG0673@2|Bacteria,2H7WC@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158416_k127_2228678_1	298655.KI912266_gene4888	1.554e-107	361.0	COG1626@1|root,COG1626@2|Bacteria,2IFA4@201174|Actinobacteria,4ES28@85013|Frankiales	201174|Actinobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
SRR25158416_k127_2228678_0	1449353.JQMQ01000004_gene6533	1.038e-234	738.0	COG1482@1|root,COG1482@2|Bacteria,2I8X4@201174|Actinobacteria,2NF3E@228398|Streptacidiphilus	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2228678_3	1123322.KB904680_gene3288	2.363e-77	282.0	COG1940@1|root,COG1940@2|Bacteria,2I9PZ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158416_k127_2228678_5	882086.SacxiDRAFT_0177	4.506e-65	242.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria,4E34Z@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158416_k127_2228678_6	479435.Kfla_1861	2.487e-63	233.0	COG2267@1|root,COG2267@2|Bacteria,2I6PZ@201174|Actinobacteria,4DRUR@85009|Propionibacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_2228678_7	1304865.JAGF01000001_gene1659	8.301e-60	209.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_2228678_8	1445613.JALM01000016_gene6175	1.638e-41	154.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4E5R7@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_2228678_9	134676.ACPL_4749	4.082e-23	99.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4DBVX@85008|Micromonosporales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158416_k127_2236754_2	999541.bgla_2g20240	7.329e-19	93.0	COG1028@1|root,COG1028@2|Bacteria,1Q7EW@1224|Proteobacteria,2VSPV@28216|Betaproteobacteria,1KGKF@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158416_k127_2236754_0	1283283.ATXA01000019_gene2913	1.54e-40	154.0	2F6TA@1|root,33Z9F@2|Bacteria,2IM6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2236754_1	1283283.ATXA01000019_gene2914	2.468e-37	150.0	COG0640@1|root,COG0640@2|Bacteria,2I2TF@201174|Actinobacteria,4EXH1@85013|Frankiales	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
SRR25158416_k127_2236754_3	1125863.JAFN01000001_gene1700	0.0002575	49.0	COG1404@1|root,COG2755@1|root,COG1404@2|Bacteria,COG2755@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158416_k127_2277237_2	35754.JNYJ01000012_gene979	3.284e-176	557.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4D98B@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158416_k127_2277237_3	710696.Intca_1683	2.568e-174	551.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4FEE7@85021|Intrasporangiaceae	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158416_k127_2277237_4	1122611.KB903971_gene2674	4.95e-123	403.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4EHPS@85012|Streptosporangiales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158416_k127_2277237_5	1120950.KB892793_gene2369	3.127e-110	364.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4DPVQ@85009|Propionibacteriales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158416_k127_2277237_1	479435.Kfla_3255	3.756e-298	927.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4DN4X@85009|Propionibacteriales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158416_k127_2277237_6	100226.SCO1356	2.942e-33	135.0	COG2146@1|root,COG2146@2|Bacteria,2IKSY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158416_k127_2277237_7	465541.ATCJ01000005_gene7057	9.831e-31	127.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158416_k127_2277237_0	1048339.KB913029_gene4399	0.0	1585.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4ERXD@85013|Frankiales	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158416_k127_2277237_8	321327.CYA_1004	1.554e-06	55.0	2A6DV@1|root,30V6R@2|Bacteria,1GH6M@1117|Cyanobacteria,1H3FH@1129|Synechococcus	1117|Cyanobacteria	S	Peptidase propeptide YPEB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
SRR25158416_k127_2292322_1	105420.BBPO01000008_gene2698	1.633e-44	162.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,2NFE7@228398|Streptacidiphilus	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158416_k127_2292322_2	5346.XP_001835054.2	2.223e-06	59.0	2CZB2@1|root,2S9FN@2759|Eukaryota,3A6QM@33154|Opisthokonta,3PEV1@4751|Fungi,3V5ZG@5204|Basidiomycota,22AG2@155619|Agaricomycetes,3W940@5338|Agaricales	4751|Fungi	I	Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
SRR25158416_k127_2292322_0	58123.JOFJ01000005_gene1294	1.285e-305	960.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,4EM26@85012|Streptosporangiales	201174|Actinobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158416_k127_2303145_6	33876.JNXY01000004_gene1611	3.768e-29	124.0	COG0778@1|root,COG0778@2|Bacteria,2IBC5@201174|Actinobacteria,4DCKZ@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2303145_8	1041159.AZUW01000006_gene1906	3.826e-19	90.0	COG4312@1|root,COG4312@2|Bacteria,1QIBA@1224|Proteobacteria,2TTFP@28211|Alphaproteobacteria,4B7GU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_2303145_1	1267534.KB906756_gene151	5.31e-73	250.0	COG4312@1|root,COG4312@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_2303145_2	926550.CLDAP_36410	7.807e-69	252.0	COG3507@1|root,COG3507@2|Bacteria,2G7I9@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolases family 43	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
SRR25158416_k127_2303145_5	1229780.BN381_80274	3.637e-33	137.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158416_k127_2303145_3	1211815.CBYP010000056_gene3330	1.201e-66	244.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_2303145_9	685727.REQ_13660	2.489e-18	86.0	28KUD@1|root,2ZAB6@2|Bacteria,2IACK@201174|Actinobacteria,4FZG7@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2303145_0	436229.JOEH01000026_gene2364	3.611e-179	575.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,2NIW0@228398|Streptacidiphilus	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158416_k127_2303145_7	479433.Caci_0956	3.63e-24	106.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_2303145_4	103733.JNYO01000014_gene3780	1.631e-47	177.0	COG0251@1|root,COG0251@2|Bacteria,2I27U@201174|Actinobacteria,4E3ZR@85010|Pseudonocardiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_2307274_4	1386089.N865_10490	7.64e-42	156.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4FH9J@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158416_k127_2307274_3	2002.JOEQ01000005_gene3528	1.505e-47	181.0	COG1186@1|root,COG1186@2|Bacteria,2IFEJ@201174|Actinobacteria,4EJNN@85012|Streptosporangiales	201174|Actinobacteria	J	RF-1 domain	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158416_k127_2307274_1	188626.HMPREF0321_0183	3.599e-216	677.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,1ZWHW@145357|Dermacoccaceae	201174|Actinobacteria	L	PFAM Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158416_k127_2307274_0	471853.Bcav_0209	1.069e-277	871.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_2307274_2	471853.Bcav_0211	3.247e-143	459.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_2312729_17	446469.Sked_07750	3.057e-13	72.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_2312729_6	1449069.JMLO01000008_gene3495	1.89e-76	268.0	COG0451@1|root,COG0451@2|Bacteria,2GN2J@201174|Actinobacteria,4FZ35@85025|Nocardiaceae	201174|Actinobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158416_k127_2312729_1	118168.MC7420_892	1.405e-162	550.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria,1H8AN@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PG_binding_1,Response_reg,dCache_1
SRR25158416_k127_2312729_10	118173.KB235914_gene2451	7.238e-47	175.0	COG0745@1|root,COG0745@2|Bacteria,1G5XG@1117|Cyanobacteria,1HB6Y@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_2312729_18	56110.Oscil6304_3387	2.476e-05	56.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4
SRR25158416_k127_2312729_3	929712.KI912613_gene249	1.349e-111	388.0	COG0814@1|root,COG0814@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	Trp_Tyr_perm
SRR25158416_k127_2312729_4	765420.OSCT_2174	1.733e-88	299.0	COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia	32061|Chloroflexia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRR25158416_k127_2312729_11	1380390.JIAT01000009_gene1060	6.142e-45	184.0	COG0596@1|root,COG0596@2|Bacteria,2GRNC@201174|Actinobacteria,4CSCP@84995|Rubrobacteria	84995|Rubrobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158416_k127_2312729_13	443218.AS9A_0184	2.147e-22	108.0	2ESKJ@1|root,33K55@2|Bacteria,2GZX4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2312729_0	526225.Gobs_0802	2.534e-236	756.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4ERYX@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	pknK_3	-	2.7.11.1	ko:K08282,ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12
SRR25158416_k127_2312729_12	1079986.JH164851_gene1285	8.748e-36	139.0	COG0596@1|root,COG0596@2|Bacteria,2I4XA@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158416_k127_2312729_15	284031.JNXD01000040_gene7170	9.725e-20	94.0	COG0596@1|root,COG0596@2|Bacteria,2I4XA@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158416_k127_2312729_19	1207063.P24_17558	0.0001233	46.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria,2JW58@204441|Rhodospirillales	204441|Rhodospirillales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
SRR25158416_k127_2312729_8	1108045.GORHZ_036_00080	1.955e-71	250.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158416_k127_2312729_9	68260.JOAY01000034_gene2583	2.567e-53	197.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_2312729_21	1236902.ANAS01000005_gene4945	0.0004643	49.0	COG1366@1|root,COG1366@2|Bacteria,2IHP9@201174|Actinobacteria,4EK6E@85012|Streptosporangiales	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158416_k127_2312729_20	1120949.KB903357_gene4882	0.00025	45.0	COG0596@1|root,COG0596@2|Bacteria,2GM5K@201174|Actinobacteria,4DAB3@85008|Micromonosporales	201174|Actinobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158416_k127_2312729_5	1298880.AUEV01000002_gene1440	6.577e-87	294.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158416_k127_2312729_7	1380393.JHVP01000003_gene1104	1.328e-73	258.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	2|Bacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158416_k127_2312729_2	497964.CfE428DRAFT_0631	6.26e-124	434.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158416_k127_2312729_16	1123251.ATWM01000025_gene1482	4.842e-17	81.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,4FI73@85021|Intrasporangiaceae	201174|Actinobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158416_k127_2324612_0	2002.JOEQ01000008_gene1129	6.783e-140	448.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4EIXN@85012|Streptosporangiales	201174|Actinobacteria	S	Phenazine biosynthesis-like protein	phzF	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158416_k127_2324612_1	1380390.JIAT01000016_gene5471	3.813e-119	394.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,2GKDT@201174|Actinobacteria,4CS52@84995|Rubrobacteria	84995|Rubrobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRR25158416_k127_2327080_0	1169152.AXVD01000007_gene2041	3.053e-155	497.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria,4G3TF@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_2327080_3	494419.ALPM01000100_gene1064	3.529e-58	207.0	COG1961@1|root,COG1961@2|Bacteria,2IG7A@201174|Actinobacteria,1WA9G@1268|Micrococcaceae	201174|Actinobacteria	L	Helix-turn-helix domain of resolvase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
SRR25158416_k127_2327080_4	455632.SGR_2603	8.161e-07	60.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,41B9R@629295|Streptomyces griseus group	201174|Actinobacteria	K	Helix-turn-helix	clgR	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158416_k127_2327080_1	479431.Namu_1000	3.507e-119	387.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,2GMWU@201174|Actinobacteria,4ETHD@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
SRR25158416_k127_2327080_2	1211815.CBYP010000071_gene1312	6.409e-81	281.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4ERT2@85013|Frankiales	201174|Actinobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158416_k127_2329540_2	1229780.BN381_80286	3.861e-06	51.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,3UWVZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_2329540_0	1463825.JNXC01000002_gene4617	1.142e-49	186.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4E1UW@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_2329540_3	479434.Sthe_0441	6.327e-06	51.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158416_k127_2332413_25	469371.Tbis_0195	1.468e-19	91.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DXH0@85010|Pseudonocardiales	201174|Actinobacteria	M	Penicillin-binding Protein	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158416_k127_2332413_20	105422.BBPM01000067_gene394	4.729e-46	169.0	2CC1Y@1|root,32TCV@2|Bacteria,2IQEP@201174|Actinobacteria,2NJ59@228398|Streptacidiphilus	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158416_k127_2332413_2	1210046.B277_07663	5.34e-151	495.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4FFB0@85021|Intrasporangiaceae	201174|Actinobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158416_k127_2332413_7	471852.Tcur_4924	1.807e-112	373.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4EGQR@85012|Streptosporangiales	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158416_k127_2332413_3	1464048.JNZS01000038_gene3989	7.018e-142	472.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4D9KJ@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158416_k127_2332413_0	543632.JOJL01000007_gene5535	3.104e-170	539.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DAHS@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bkdB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158416_k127_2332413_1	1123320.KB889664_gene1240	6.509e-160	512.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase E1 component	pdhA2	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158416_k127_2332413_17	1449976.KALB_3066	3.259e-66	229.0	COG1522@1|root,COG1522@2|Bacteria,2HVG9@201174|Actinobacteria,4E414@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158416_k127_2332413_16	1464048.JNZS01000009_gene5727	6.442e-67	238.0	COG1506@1|root,COG1506@2|Bacteria,2I3Z4@201174|Actinobacteria,4DCIS@85008|Micromonosporales	201174|Actinobacteria	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6,Peptidase_S9
SRR25158416_k127_2332413_24	1120950.KB892762_gene5493	1.035e-25	106.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,4DS7G@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158416_k127_2332413_18	1283287.KB822575_gene584	1.611e-65	229.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4DQIS@85009|Propionibacteriales	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158416_k127_2332413_12	1120950.KB892762_gene5491	8.265e-80	275.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4DQHA@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158416_k127_2332413_11	1150864.MILUP08_46773	5.11e-80	278.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4D9MK@85008|Micromonosporales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_2332413_8	105425.BBPL01000008_gene1551	3.47e-105	346.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,2NFJS@228398|Streptacidiphilus	201174|Actinobacteria	T	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158416_k127_2332413_6	1120950.KB892762_gene5486	6.431e-117	379.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4DNJN@85009|Propionibacteriales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158416_k127_2332413_13	1120950.KB892762_gene5484	1.663e-78	274.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4DQJF@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158416_k127_2332413_9	1120950.KB892762_gene5483	1.294e-84	303.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4DPBR@85009|Propionibacteriales	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158416_k127_2332413_5	1120950.KB892762_gene5482	7.849e-122	405.0	COG2267@1|root,COG2267@2|Bacteria,2I2IM@201174|Actinobacteria,4DQ6A@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_2332413_23	479435.Kfla_0462	2.647e-27	117.0	2DPPE@1|root,332VJ@2|Bacteria,2IN30@201174|Actinobacteria,4DSE1@85009|Propionibacteriales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158416_k127_2332413_4	1352941.M877_17300	1.415e-139	457.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158416_k127_2332413_15	710111.FraQA3DRAFT_0963	2.062e-73	271.0	COG0438@1|root,COG0438@2|Bacteria,2I8FJ@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_2332413_22	221288.JH992901_gene5371	1.707e-35	155.0	COG0110@1|root,COG0110@2|Bacteria,1GA9N@1117|Cyanobacteria,1JIJD@1189|Stigonemataceae	1117|Cyanobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158416_k127_2332413_19	710111.FraQA3DRAFT_2107	3.865e-59	216.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Methyltransf_11,Methyltransf_23
SRR25158416_k127_2332413_26	1463864.JOGO01000004_gene923	6.504e-06	51.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158416_k127_2332413_21	1449347.JQLN01000005_gene4648	1.195e-40	158.0	COG1309@1|root,COG1309@2|Bacteria,2IA4D@201174|Actinobacteria,2M5QT@2063|Kitasatospora	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158416_k127_2332413_14	1380356.JNIK01000005_gene892	6.876e-74	261.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158416_k127_2332413_10	35754.JNYJ01000023_gene8278	1.896e-84	282.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4DANH@85008|Micromonosporales	201174|Actinobacteria	P	Bacterial Na+/H+ antiporter B (NhaB)	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
SRR25158416_k127_2341464_6	1172180.KB911775_gene6020	1.055e-69	237.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158416_k127_2341464_7	1303692.SFUL_105	1.026e-59	215.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158416_k127_2341464_9	1120950.KB892718_gene2431	4.689e-25	107.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,4DWS8@85009|Propionibacteriales	201174|Actinobacteria	L	Transposase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158416_k127_2341464_4	1108045.GORHZ_197_00320	2.194e-76	260.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4GC4V@85026|Gordoniaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_2341464_5	33898.JRHJ01000043_gene3758	2.214e-75	255.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_2341464_12	1157637.KB892102_gene1424	0.0001163	49.0	COG1063@1|root,COG1063@2|Bacteria,2HCBE@201174|Actinobacteria	201174|Actinobacteria	E	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2341464_0	68219.JNXI01000040_gene5462	3.018e-156	515.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
SRR25158416_k127_2341464_2	240292.Ava_3981	1.484e-94	320.0	COG0451@1|root,COG0451@2|Bacteria,1GDDM@1117|Cyanobacteria	1117|Cyanobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2341464_1	935866.JAER01000050_gene879	5.509e-107	355.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DN9S@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158416_k127_2341464_3	1172185.KB911516_gene2558	1.471e-88	304.0	COG2267@1|root,COG2267@2|Bacteria,2I3KS@201174|Actinobacteria,4G9UP@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158416_k127_2341464_11	1134912.AJTV01000042_gene3593	2.899e-10	61.0	COG4828@1|root,COG4828@2|Bacteria,1N984@1224|Proteobacteria,2UBT7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
SRR25158416_k127_2344209_3	1003195.SCAT_2039	1.285e-124	416.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158416_k127_2344209_6	1123251.ATWM01000003_gene995	8.417e-41	154.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4FHAS@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158416_k127_2344209_2	1348663.KCH_30840	2.914e-132	428.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,2M0AK@2063|Kitasatospora	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158416_k127_2344209_1	570268.ANBB01000052_gene2948	7.395e-168	545.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4EFGM@85012|Streptosporangiales	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158416_k127_2344209_4	1223523.H340_26931	1.085e-103	346.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2344209_5	1120950.KB892759_gene6280	5.573e-59	215.0	2DDJY@1|root,32U1P@2|Bacteria,2HZ8D@201174|Actinobacteria,4DR2E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158416_k127_2344209_0	134676.ACPL_2998	7.728e-179	578.0	COG3291@1|root,COG4412@1|root,COG5563@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5563@2|Bacteria,2I4WM@201174|Actinobacteria,4DC3P@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF1929)	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF1929,F5_F8_type_C,Kelch_4,Kelch_6
SRR25158416_k127_2347631_16	1120949.KB903315_gene170	2.249e-36	138.0	COG0412@1|root,COG0412@2|Bacteria,2GTZG@201174|Actinobacteria,4DDTB@85008|Micromonosporales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158416_k127_2347631_15	446470.Snas_1441	2.801e-42	166.0	COG0640@1|root,COG0640@2|Bacteria,2IA2N@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_2347631_10	1122933.JNIY01000003_gene240	3.299e-99	340.0	COG0477@1|root,COG0477@2|Bacteria,2I377@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_2347631_8	1121933.AUHH01000002_gene1854	9.742e-102	350.0	COG2234@1|root,COG2234@2|Bacteria,2GIT0@201174|Actinobacteria,4DQCH@85009|Propionibacteriales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158416_k127_2347631_1	1120950.KB892762_gene5452	0.0	1099.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4DPFE@85009|Propionibacteriales	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158416_k127_2347631_23	1394178.AWOO02000007_gene3210	2.548e-15	81.0	COG2172@1|root,COG2172@2|Bacteria,2IHNR@201174|Actinobacteria,4EJ45@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158416_k127_2347631_14	1123320.KB889585_gene1741	3.734e-46	169.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158416_k127_2347631_2	1120950.KB892762_gene5454	3.497e-309	968.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4DNQG@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158416_k127_2347631_7	1394178.AWOO02000020_gene7494	5.509e-107	355.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4EGE7@85012|Streptosporangiales	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158416_k127_2347631_20	196162.Noca_1119	3.362e-26	121.0	COG0739@1|root,COG0791@1|root,COG1876@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,COG1876@2|Bacteria,2ICD5@201174|Actinobacteria,4DS12@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,Peptidase_M23,VanY
SRR25158416_k127_2347631_25	235985.BBPN01000013_gene6723	5.164e-10	68.0	2EGB2@1|root,33A2X@2|Bacteria,2GQUA@201174|Actinobacteria,2NJKW@228398|Streptacidiphilus	201174|Actinobacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158416_k127_2347631_24	28444.JODQ01000014_gene6781	3.883e-10	64.0	2EHCF@1|root,33B4A@2|Bacteria,2I1J2@201174|Actinobacteria,4EM12@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4244
SRR25158416_k127_2347631_19	1123320.KB889646_gene5413	6.285e-28	125.0	COG2064@1|root,COG2064@2|Bacteria,2IQE9@201174|Actinobacteria	201174|Actinobacteria	NU	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_2347631_22	1236902.ANAS01000030_gene3001	1.051e-17	96.0	COG4965@1|root,COG4965@2|Bacteria,2I8NR@201174|Actinobacteria,4EJYE@85012|Streptosporangiales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_2347631_5	1003195.SCAT_2868	1.192e-138	453.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system protein e	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158416_k127_2347631_9	1343740.M271_26520	1.017e-99	340.0	COG0489@1|root,COG0489@2|Bacteria,2I2TA@201174|Actinobacteria	201174|Actinobacteria	D	protein tyrosine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158416_k127_2347631_6	1306406.ASHX01000001_gene1383	6.393e-119	394.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	serB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158416_k127_2347631_13	471852.Tcur_4840	5.617e-49	184.0	COG3177@1|root,COG3177@2|Bacteria,2GIT8@201174|Actinobacteria,4EG60@85012|Streptosporangiales	201174|Actinobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158416_k127_2347631_12	266940.Krad_0454	7.013e-62	221.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_2347631_11	928724.SacglDRAFT_03812	4.899e-77	263.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4E2ZX@85010|Pseudonocardiales	201174|Actinobacteria	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158416_k127_2347631_0	1048339.KB913029_gene1213	0.0	1104.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158416_k127_2347631_17	266779.Meso_4061	3.697e-34	134.0	COG3832@1|root,COG3832@2|Bacteria,1RAW4@1224|Proteobacteria,2UI5Z@28211|Alphaproteobacteria,43P5K@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_2347631_18	710686.Mycsm_04185	7.287e-29	118.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,23AX1@1762|Mycobacteriaceae	201174|Actinobacteria	K	arsR family	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158416_k127_2347631_3	1120950.KB892756_gene6668	3.042e-250	784.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4DNPC@85009|Propionibacteriales	201174|Actinobacteria	C	FAD dependent oxidoreductase	glpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158416_k127_2347631_4	1278078.G419_25152	6.619e-231	724.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4FVX5@85025|Nocardiaceae	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158416_k127_2347631_21	1306174.JODP01000010_gene6933	1.454e-20	95.0	COG0517@1|root,COG0517@2|Bacteria,2IIM3@201174|Actinobacteria	201174|Actinobacteria	P	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158416_k127_2350080_3	930171.Asphe3_23910	2.044e-30	124.0	COG3832@1|root,COG3832@2|Bacteria,2HK0N@201174|Actinobacteria,1WC5C@1268|Micrococcaceae	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2350080_1	1394178.AWOO02000004_gene2489	1.073e-37	147.0	COG4974@1|root,COG4974@2|Bacteria,2HU0B@201174|Actinobacteria,4EQCU@85012|Streptosporangiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158416_k127_2350080_0	1123251.ATWM01000002_gene51	8.161e-69	254.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4FFEX@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_2350080_4	1348663.KCH_60810	1.841e-05	53.0	2E1HJ@1|root,32WVP@2|Bacteria,2IBY1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4241)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4241
SRR25158416_k127_2350080_2	1304865.JAGF01000001_gene2174	3.225e-37	144.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158416_k127_2350438_1	1380386.JIAW01000005_gene1413	2.715e-109	357.0	COG2267@1|root,COG2267@2|Bacteria,2I1RU@201174|Actinobacteria,239QW@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_2350438_2	208444.JNYY01000014_gene4289	3.934e-19	93.0	COG0262@1|root,COG0262@2|Bacteria,2H16K@201174|Actinobacteria,4EEN8@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_2350438_0	66874.JOFS01000003_gene7103	1.108e-121	395.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_23666_8	1380356.JNIK01000005_gene886	6.308e-102	334.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4ERSZ@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
SRR25158416_k127_23666_4	1120950.KB892707_gene4910	1.634e-153	502.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4DPP5@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158416_k127_23666_11	1120950.KB892707_gene4911	5.632e-98	323.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4DNSZ@85009|Propionibacteriales	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158416_k127_23666_10	196162.Noca_3042	7.508e-99	329.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4DPJU@85009|Propionibacteriales	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158416_k127_23666_12	469371.Tbis_3030	5.631e-70	245.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158416_k127_23666_6	266940.Krad_3173	8.071e-116	378.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria	201174|Actinobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158416_k127_23666_15	471852.Tcur_2891	8.932e-48	177.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4EJGT@85012|Streptosporangiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_23666_7	1306406.ASHX01000001_gene3238	8.909e-115	384.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158416_k127_23666_2	58123.JOFJ01000001_gene3001	7.365e-226	715.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EG83@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_23666_0	1120936.KB907210_gene5671	1.894e-253	794.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EGNQ@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_23666_17	269800.Tfu_2084	1.717e-30	130.0	2EGCD@1|root,33A46@2|Bacteria,2I14B@201174|Actinobacteria,4EKUH@85012|Streptosporangiales	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
SRR25158416_k127_23666_13	471852.Tcur_2879	8.873e-55	194.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4EJM8@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
SRR25158416_k127_23666_1	1120950.KB892707_gene4953	3.778e-229	721.0	COG1169@1|root,COG1169@2|Bacteria,2I50A@201174|Actinobacteria,4DX2J@85009|Propionibacteriales	201174|Actinobacteria	HQ	Anthranilate synthase component I, N terminal region	trpE	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158416_k127_23666_19	1146883.BLASA_2276	4.167e-18	91.0	2EGC7@1|root,33A40@2|Bacteria,2HEC9@201174|Actinobacteria,4ETGQ@85013|Frankiales	201174|Actinobacteria	S	Trp biosynthesis associated, transmembrane protein, Oprn Chp	-	-	-	-	-	-	-	-	-	-	-	-	Trp_oprn_chp
SRR25158416_k127_23666_18	356851.JOAN01000004_gene1186	4.881e-28	116.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4D8UG@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_23666_5	1120950.KB892707_gene4966	4.894e-119	392.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DNTB@85009|Propionibacteriales	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158416_k127_23666_3	1048339.KB913029_gene4534	2.383e-201	634.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4ERSM@85013|Frankiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
SRR25158416_k127_23666_9	710111.FraQA3DRAFT_6540	4e-100	335.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4ERZA@85013|Frankiales	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158416_k127_23666_14	365528.KB891233_gene1728	4.195e-48	183.0	COG1651@1|root,COG1651@2|Bacteria,2GKH8@201174|Actinobacteria,4ETBH@85013|Frankiales	201174|Actinobacteria	O	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158416_k127_23666_16	1120948.KB903240_gene3975	7.334e-37	140.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4DYUZ@85010|Pseudonocardiales	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158416_k127_2367747_2	44060.JODL01000016_gene4393	6.786e-134	431.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_2367747_1	33898.JRHJ01000014_gene4238	2.624e-145	466.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158416_k127_2367747_4	749414.SBI_04893	1.264e-89	303.0	COG1309@1|root,COG1309@2|Bacteria,2GQBQ@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158416_k127_2367747_0	1122138.AQUZ01000018_gene7522	4.531e-187	590.0	COG0388@1|root,COG0388@2|Bacteria,2H03Y@201174|Actinobacteria,4DV19@85009|Propionibacteriales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1,3.5.5.7	ko:K01501,ko:K01502	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05358,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC01336,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158416_k127_2367747_3	1146883.BLASA_0996	1.109e-93	323.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,4EV1B@85013|Frankiales	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158416_k127_2367747_6	35754.JNYJ01000007_gene2942	2.332e-40	154.0	COG5649@1|root,COG5649@2|Bacteria,2GRMZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158416_k127_2367747_5	105422.BBPM01000048_gene1641	2.982e-57	203.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,2NIXH@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158416_k127_2367747_8	134676.ACPL_5338	1.074e-28	119.0	COG1983@1|root,COG1983@2|Bacteria,2HUTN@201174|Actinobacteria,4DFZ7@85008|Micromonosporales	201174|Actinobacteria	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
SRR25158416_k127_2367747_7	479431.Namu_0491	1.051e-39	150.0	COG1359@1|root,COG1359@2|Bacteria,2GSE1@201174|Actinobacteria,4EX0G@85013|Frankiales	201174|Actinobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
SRR25158416_k127_238622_0	106370.Francci3_4167	3.775e-84	283.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR25158416_k127_238622_2	298655.KI912266_gene1692	1.097e-09	59.0	COG3316@1|root,COG3316@2|Bacteria	2|Bacteria	-	-	tnp	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR25158416_k127_238622_1	1122609.AUGT01000011_gene3628	3.637e-28	117.0	COG0262@1|root,COG0262@2|Bacteria,2ING3@201174|Actinobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_2401844_0	494419.ALPM01000034_gene3290	3.687e-116	376.0	2DB9H@1|root,2Z7WW@2|Bacteria,2I2TQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
SRR25158416_k127_2401844_3	1120949.KB903326_gene3130	5.272e-29	134.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2I90E@201174|Actinobacteria,4DBRN@85008|Micromonosporales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158416_k127_2401844_1	1906.SFRA_11905	2.064e-76	266.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_2401844_2	44060.JODL01000008_gene1098	2.165e-40	154.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158416_k127_2459165_0	1206731.BAGB01000121_gene9341	2.027e-99	328.0	COG3039@1|root,COG3039@2|Bacteria,2IERV@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
SRR25158416_k127_2459165_1	1246459.KB898374_gene3976	3.531e-39	161.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158416_k127_2459165_4	288000.BBta_p0056	3.761e-12	74.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JQNW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158416_k127_2459165_2	1348583.ATLH01000013_gene2762	7.76e-25	122.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia,1FA5V@104264|Cellulophaga	976|Bacteroidetes	C	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
SRR25158416_k127_2459165_5	1480694.DC28_12460	9.248e-09	69.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K09766,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	DUF2225,HTH_Crp_2,cNMP_binding
SRR25158416_k127_2459165_3	222534.KB893694_gene55	4.572e-20	92.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4EU6E@85013|Frankiales	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158416_k127_2460374_0	1299327.I546_3208	6.111e-74	252.0	COG1028@1|root,COG1028@2|Bacteria,2IAN1@201174|Actinobacteria,236K8@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158416_k127_2460374_1	1396141.BATP01000020_gene23	7.026e-47	175.0	COG0262@1|root,COG0262@2|Bacteria,46WG0@74201|Verrucomicrobia,2IVHY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_2460374_2	744979.R2A130_3014	1.145e-19	96.0	COG0251@1|root,COG0251@2|Bacteria,1RDFC@1224|Proteobacteria,2U8PR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_2463027_1	1048339.KB913029_gene3508	4.14e-32	132.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4ERG2@85013|Frankiales	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158416_k127_2463027_0	269800.Tfu_2441	1.143e-172	562.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2GNSN@201174|Actinobacteria,4EH2B@85012|Streptosporangiales	201174|Actinobacteria	P	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA,VWA_2
SRR25158416_k127_2470911_2	298654.FraEuI1c_1418	1.598e-94	310.0	COG3832@1|root,COG3832@2|Bacteria,2IFBH@201174|Actinobacteria,4ETPA@85013|Frankiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_2470911_4	1304865.JAGF01000001_gene231	3.652e-65	224.0	COG0640@1|root,COG0640@2|Bacteria,2IHS2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158416_k127_2470911_1	1283283.ATXA01000008_gene2984	1.06e-149	478.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4EWWQ@85013|Frankiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_2470911_3	1380393.JHVP01000015_gene4172	7.02e-75	255.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4EVNQ@85013|Frankiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158416_k127_2470911_0	931627.MycrhDRAFT_5250	2.385e-286	886.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,23CRV@1762|Mycobacteriaceae	201174|Actinobacteria	O	Cyclic nucleotide-monophosphate binding domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158416_k127_2472915_1	1206101.AZXC01000006_gene4046	4.839e-109	359.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158416_k127_2472915_0	1120950.KB892779_gene930	4.888e-130	428.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4DRAS@85009|Propionibacteriales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158416_k127_2493531_2	1463879.JOHP01000005_gene6032	1.046e-36	138.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria	201174|Actinobacteria	H	reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_2493531_1	436229.JOEH01000007_gene4030	2.865e-104	342.0	COG0572@1|root,COG0572@2|Bacteria,2GMCP@201174|Actinobacteria,2NEDH@228398|Streptacidiphilus	201174|Actinobacteria	F	Cytidylate kinase-like family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,PRK
SRR25158416_k127_2493531_0	653045.Strvi_7628	1.031e-157	503.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158416_k127_2493531_4	640132.Srot_1173	0.0001527	46.0	COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria	2|Bacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
SRR25158416_k127_2493531_3	298654.FraEuI1c_6175	3.507e-08	56.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	cvnC6	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR25158416_k127_2494464_8	512565.AMIS_15770	1.536e-56	209.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4DBM5@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
SRR25158416_k127_2494464_6	196162.Noca_3009	1.562e-88	301.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria,4DPPY@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
SRR25158416_k127_2494464_0	1048339.KB913029_gene4521	0.0	1249.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4ES9K@85013|Frankiales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158416_k127_2494464_7	253839.SSNG_01807	7.98e-66	240.0	COG2951@1|root,COG3266@1|root,COG2951@2|Bacteria,COG3266@2|Bacteria,2GX49@201174|Actinobacteria	201174|Actinobacteria	M	Membrane-bound lytic murein transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158416_k127_2494464_9	1048339.KB913029_gene4519	8.77e-53	206.0	COG2244@1|root,COG2244@2|Bacteria,2GJV2@201174|Actinobacteria,4EVSZ@85013|Frankiales	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
SRR25158416_k127_2494464_2	1120950.KB892707_gene5007	4.279e-262	818.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4DPIM@85009|Propionibacteriales	201174|Actinobacteria	J	ribosomal protein	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158416_k127_2494464_14	446462.Amir_5521	0.0002094	51.0	2ESZ1@1|root,33KH9@2|Bacteria,2IIDM@201174|Actinobacteria,4E3GN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2494464_11	33876.JNXY01000001_gene5757	3.924e-49	181.0	COG0071@1|root,COG0071@2|Bacteria,2GQGQ@201174|Actinobacteria,4DEMD@85008|Micromonosporales	201174|Actinobacteria	O	Hsp20/alpha crystallin family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158416_k127_2494464_4	1123024.AUII01000012_gene4225	4.644e-131	429.0	COG0237@1|root,COG2320@1|root,COG0237@2|Bacteria,COG2320@2|Bacteria,2GN96@201174|Actinobacteria,4DYSR@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158416_k127_2494464_1	1048339.KB913029_gene4503	0.0	1155.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4ERJA@85013|Frankiales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158416_k127_2494464_12	512565.AMIS_52830	7.693e-48	181.0	COG2315@1|root,COG2315@2|Bacteria,2HR7I@201174|Actinobacteria,4DFE0@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158416_k127_2494464_13	1032480.MLP_46600	7.374e-11	64.0	COG3391@1|root,COG3391@2|Bacteria,2H6RD@201174|Actinobacteria,4DWBM@85009|Propionibacteriales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2494464_3	1121946.AUAX01000024_gene7568	2.189e-140	452.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4D8XF@85008|Micromonosporales	201174|Actinobacteria	P	Membrane protein TerC, possibly involved in tellurium resistance	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158416_k127_2494464_5	1120950.KB892748_gene3183	2.094e-93	317.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,4DPUP@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_2494464_10	263358.VAB18032_26105	1.139e-52	195.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria,4D9XX@85008|Micromonosporales	201174|Actinobacteria	G	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_C,MDMPI_N
SRR25158416_k127_2495732_4	1179773.BN6_32750	2.222e-16	79.0	2C1XE@1|root,301BZ@2|Bacteria,2IGAE@201174|Actinobacteria,4E3XG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2495732_3	455632.SGR_616	2.959e-26	116.0	29A0V@1|root,2ZX2D@2|Bacteria,2GTWP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2495732_1	653045.Strvi_5277	1.56e-134	445.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158416_k127_2495732_0	710696.Intca_3344	8.427e-199	631.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,4FFQ1@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158416_k127_2495732_2	1121924.ATWH01000010_gene1013	1.273e-71	248.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4FP5A@85023|Microbacteriaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,HTH_20
SRR25158416_k127_2501346_1	1210046.B277_12161	1.299e-57	202.0	COG2064@1|root,COG2064@2|Bacteria,2GKMW@201174|Actinobacteria,4FENF@85021|Intrasporangiaceae	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_2501346_0	1120950.KB892764_gene5643	8.475e-102	340.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4DP2Z@85009|Propionibacteriales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_2501346_4	1120959.ATXF01000010_gene49	2.782e-13	72.0	2EG89@1|root,33A03@2|Bacteria,2GX3U@201174|Actinobacteria,4FQQM@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2501346_2	471853.Bcav_2787	4.968e-26	114.0	2CXFQ@1|root,32T1V@2|Bacteria,2GQYH@201174|Actinobacteria	201174|Actinobacteria	S	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158416_k127_2501346_3	1120950.KB892764_gene5646	8.135e-25	115.0	2E9Y4@1|root,3343S@2|Bacteria,2GR3H@201174|Actinobacteria,4DRMM@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2501346_5	452863.Achl_2402	1.928e-08	60.0	2EBSZ@1|root,335SP@2|Bacteria,2GUT0@201174|Actinobacteria,1WA5M@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158416_k127_2513714_1	479431.Namu_0261	1.521e-142	461.0	COG2233@1|root,COG3195@1|root,COG2233@2|Bacteria,COG3195@2|Bacteria,2GMH6@201174|Actinobacteria	201174|Actinobacteria	F	Xanthine uracil	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	OHCU_decarbox,Xan_ur_permease
SRR25158416_k127_2513714_0	1313172.YM304_25340	8.395e-163	525.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158416_k127_2566331_7	994479.GL877878_gene3146	3.769e-107	348.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria,4DXCB@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_2566331_10	743718.Isova_0221	1.918e-75	274.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4F4BM@85017|Promicromonosporaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_2566331_9	479432.Sros_0822	3.73e-82	277.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria,4EK4Y@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158416_k127_2566331_3	1120950.KB892720_gene1920	6.66e-175	561.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4DP4I@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158416_k127_2566331_2	1155714.KB891996_gene3649	8.431e-192	616.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158416_k127_2566331_11	1160718.SU9_11098	2.409e-69	242.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2607	PNP_phzG_C,Putative_PNPOx
SRR25158416_k127_2566331_4	457425.XNR_4499	1.253e-139	457.0	COG0477@1|root,COG0477@2|Bacteria,2GKFJ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
SRR25158416_k127_2566331_13	356851.JOAN01000017_gene5903	7.653e-58	210.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4DDPF@85008|Micromonosporales	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2566331_5	2002.JOEQ01000010_gene6336	2.599e-119	394.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4EFH6@85012|Streptosporangiales	201174|Actinobacteria	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3332	Amidohydro_1
SRR25158416_k127_2566331_6	436229.JOEH01000022_gene621	4.745e-112	369.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,2NGBD@228398|Streptacidiphilus	201174|Actinobacteria	G	Haloacid dehalogenase-like hydrolase	nagD	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158416_k127_2566331_12	1463825.JNXC01000003_gene3926	5.415e-65	240.0	COG1192@1|root,COG1192@2|Bacteria,2H4UC@201174|Actinobacteria,4DZB6@85010|Pseudonocardiales	201174|Actinobacteria	D	involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRR25158416_k127_2566331_8	397278.JOJN01000011_gene1608	3.307e-90	303.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4DP20@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix diphteria tox regulatory element	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158416_k127_2566331_18	1120950.KB892768_gene5357	3.641e-05	51.0	2EQ5R@1|root,33HS1@2|Bacteria,2GRI3@201174|Actinobacteria,4DVM8@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2566331_0	479435.Kfla_4711	0.0	1055.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4DP3E@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM peptidase M6, immune inhibitor A	ina	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
SRR25158416_k127_2566331_16	543632.JOJL01000045_gene3540	2.508e-38	164.0	2DQ01@1|root,32UN7@2|Bacteria,2IS50@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2566331_1	479431.Namu_0020	4.044e-212	679.0	COG4425@1|root,COG4425@2|Bacteria,2IBWT@201174|Actinobacteria,4ETTC@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta-hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158416_k127_2566331_15	1054860.KB913030_gene85	3.574e-52	193.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria	201174|Actinobacteria	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158416_k127_2566331_19	1123065.ATWL01000010_gene3112	0.0001428	50.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria	201174|Actinobacteria	D	permease	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
SRR25158416_k127_2566331_17	1122933.JNIY01000003_gene93	6.03e-22	108.0	COG0628@1|root,COG0628@2|Bacteria,2IM8N@201174|Actinobacteria	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158416_k127_2566331_14	101510.RHA1_ro00070	1.107e-53	196.0	29VND@1|root,30H5P@2|Bacteria,2IG0Q@201174|Actinobacteria,4G95E@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2607630_10	1246995.AFR_24965	3.872e-52	192.0	COG0589@1|root,COG0589@2|Bacteria,2I8XM@201174|Actinobacteria	201174|Actinobacteria	T	universal stress protein	uspA4	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158416_k127_2607630_3	644283.Micau_3633	5.565e-115	389.0	COG0520@1|root,COG0520@2|Bacteria,2GNM2@201174|Actinobacteria,4DM44@85008|Micromonosporales	201174|Actinobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158416_k127_2607630_12	1449068.JMLQ01000003_gene2438	1.42e-46	173.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4G1AK@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158416_k127_2607630_7	1150399.AQYK01000002_gene3266	2.932e-71	250.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4FP4U@85023|Microbacteriaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158416_k127_2607630_13	28444.JODQ01000007_gene5219	2.199e-46	175.0	COG0317@1|root,COG0317@2|Bacteria,2GNRE@201174|Actinobacteria,4EIIG@85012|Streptosporangiales	201174|Actinobacteria	KT	Amino acid-binding act domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
SRR25158416_k127_2607630_20	479435.Kfla_4688	6.103e-09	63.0	arCOG13021@1|root,33BFU@2|Bacteria,2GTY3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2607630_19	35754.JNYJ01000001_gene7322	1.053e-25	117.0	2EMIT@1|root,33F7D@2|Bacteria,2GRD4@201174|Actinobacteria,4DFSZ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2607630_9	743718.Isova_0246	6.311e-54	196.0	COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4F4N7@85017|Promicromonosporaceae	201174|Actinobacteria	K	MerR, DNA binding	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158416_k127_2607630_1	1122138.AQUZ01000008_gene3778	1.25e-194	621.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4DNDY@85009|Propionibacteriales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158416_k127_2607630_15	935866.JAER01000038_gene4182	6.87e-34	139.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4DRWZ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR25158416_k127_2607630_2	211114.JOEF01000037_gene6889	2.647e-148	496.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4E0D7@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
SRR25158416_k127_2607630_21	1179773.BN6_04660	8.931e-08	60.0	2DP6P@1|root,330SA@2|Bacteria,2IIM6@201174|Actinobacteria,4E53H@85010|Pseudonocardiales	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
SRR25158416_k127_2607630_8	100226.SCO4288	3.325e-67	239.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158416_k127_2607630_6	469371.Tbis_2726	7.82e-74	256.0	COG0412@1|root,COG0412@2|Bacteria,2I151@201174|Actinobacteria,4E3BE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158416_k127_2607630_14	471852.Tcur_2630	1.641e-43	165.0	2CR5C@1|root,32SNF@2|Bacteria,2IT0H@201174|Actinobacteria,4EJMI@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR25158416_k127_2607630_0	1394178.AWOO02000075_gene1993	1.479e-198	625.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4EI6X@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	thrC3	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_2607630_17	471852.Tcur_0802	2.702e-30	123.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4EKIY@85012|Streptosporangiales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158416_k127_2607630_18	1283283.ATXA01000006_gene1916	1.631e-28	122.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4ETDM@85013|Frankiales	201174|Actinobacteria	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158416_k127_2607630_11	58123.JOFJ01000017_gene4181	1.215e-49	181.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria,4EKQY@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158416_k127_2607630_4	471853.Bcav_0819	2.037e-90	306.0	28PI0@1|root,2ZC87@2|Bacteria,2IJ39@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
SRR25158416_k127_2607630_16	471853.Bcav_0820	2.405e-31	132.0	2ECMH@1|root,336JI@2|Bacteria,2GRY0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2607630_5	479435.Kfla_5990	7.034e-75	255.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNNQ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158416_k127_2608405_4	1303692.SFUL_4347	1.947e-21	95.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2GMG7@201174|Actinobacteria	201174|Actinobacteria	KT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
SRR25158416_k127_2608405_2	471853.Bcav_1789	1.287e-51	190.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158416_k127_2608405_1	350054.Mflv_2327	4.325e-56	204.0	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria,2374I@1762|Mycobacteriaceae	201174|Actinobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158416_k127_2608405_0	1240349.ANGC01000006_gene1489	3.536e-80	276.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4FXQ8@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_2608405_3	469383.Cwoe_4560	6.729e-34	143.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4CRKQ@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_2608405_7	1121934.AUDX01000002_gene2783	7.201e-09	67.0	COG0553@1|root,COG0827@1|root,COG3266@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3266@2|Bacteria,COG4646@2|Bacteria,2I378@201174|Actinobacteria,4FQZR@85023|Microbacteriaceae	201174|Actinobacteria	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII,SNF2_N
SRR25158416_k127_2608405_5	1089544.KB912942_gene2033	1.332e-20	94.0	COG0286@1|root,COG0286@2|Bacteria,2GKAQ@201174|Actinobacteria,4E4R9@85010|Pseudonocardiales	201174|Actinobacteria	V	PFAM N-6 DNA methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
SRR25158416_k127_2608405_6	1172188.KB911824_gene3381	1.181e-19	96.0	2FD8H@1|root,345AH@2|Bacteria,2GS0J@201174|Actinobacteria,4FIXE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2615245_4	266940.Krad_3531	2.589e-81	280.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158416_k127_2615245_0	58123.JOFJ01000012_gene5324	1.47e-310	966.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4EG49@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158416_k127_2615245_1	1172181.KB911702_gene708	6.977e-267	851.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
SRR25158416_k127_2615245_7	1120959.ATXF01000005_gene896	4.487e-25	107.0	2E3I3@1|root,32YGJ@2|Bacteria,2GV2N@201174|Actinobacteria,4FQCU@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
SRR25158416_k127_2615245_5	1236902.ANAS01000005_gene4679	1.751e-60	218.0	COG0706@1|root,COG0706@2|Bacteria,2GIRJ@201174|Actinobacteria,4EJQI@85012|Streptosporangiales	201174|Actinobacteria	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158416_k127_2615245_8	749414.SBI_06705	6.764e-06	51.0	28S86@1|root,2ZEJI@2|Bacteria,2IQGN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2615245_6	1120936.KB907221_gene2175	1.414e-55	201.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2615245_2	561175.KB894101_gene4525	7.111e-170	558.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria	201174|Actinobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158416_k127_2615245_3	1463920.JOGB01000010_gene6658	4.218e-139	454.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HTH_31,Transposase_20
SRR25158416_k127_2617703_3	1206743.BAGM01000008_gene3866	1.486e-92	310.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4FX0U@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158416_k127_2617703_7	284031.JNXD01000003_gene3942	1.823e-54	198.0	COG4405@1|root,COG4405@2|Bacteria,2IFEU@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_2617703_26	479432.Sros_0821	0.0002622	52.0	COG3979@1|root,COG3979@2|Bacteria	2|Bacteria	S	chitin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Pro_Al_protease,Trypsin
SRR25158416_k127_2617703_15	1123023.JIAI01000001_gene6461	2.656e-28	122.0	COG1309@1|root,COG1309@2|Bacteria,2GJVD@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_2617703_8	67257.JODR01000005_gene2226	5.56e-54	193.0	COG1444@1|root,COG1444@2|Bacteria,2IMCJ@201174|Actinobacteria	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_2617703_14	1313172.YM304_27310	1.09e-31	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF4157,SatD,Sigma70_r2
SRR25158416_k127_2617703_18	298655.KI912266_gene6084	1.249e-13	81.0	COG5401@1|root,COG5401@2|Bacteria,2H4HT@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158416_k127_2617703_20	710687.KI912270_gene4916	3.464e-12	70.0	2B45Y@1|root,31WWP@2|Bacteria,2HYE6@201174|Actinobacteria,23EN3@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2617703_5	710687.KI912270_gene4915	1.256e-60	214.0	COG0582@1|root,COG0582@2|Bacteria,2I9IX@201174|Actinobacteria,23DAZ@1762|Mycobacteriaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158416_k127_2617703_0	1048339.KB913029_gene1820	2.422e-113	398.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4EVG9@85013|Frankiales	201174|Actinobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158416_k127_2617703_17	1380393.JHVP01000003_gene1200	1.147e-22	101.0	2EF54@1|root,338Y8@2|Bacteria,2GSEE@201174|Actinobacteria,4EW9C@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2617703_23	1122182.KB903813_gene2594	9.992e-08	56.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
SRR25158416_k127_2617703_11	1463856.JOHY01000011_gene7076	1.142e-49	186.0	COG1432@1|root,COG1432@2|Bacteria,2IJBY@201174|Actinobacteria	201174|Actinobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158416_k127_2617703_2	1146883.BLASA_1964	6.83e-94	316.0	COG4974@1|root,COG4974@2|Bacteria,2HTVG@201174|Actinobacteria,4EUVH@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_2617703_16	1032480.MLP_35960	2.363e-23	103.0	2EAZS@1|root,3350M@2|Bacteria,2GS4Z@201174|Actinobacteria,4DWD5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158416_k127_2617703_1	105425.BBPL01000098_gene1243	1.177e-104	351.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,2NGQ1@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_2617703_9	298654.FraEuI1c_6621	3.274e-53	196.0	2A84P@1|root,30X5E@2|Bacteria,2IN6P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2617703_22	1283283.ATXA01000025_gene3652	1.565e-09	71.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria,4EURT@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_2617703_25	1123503.KB908060_gene44	0.0001309	53.0	COG3743@1|root,COG3743@2|Bacteria,1NN9E@1224|Proteobacteria,2UKPP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	rRNA binding	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	-
SRR25158416_k127_2617703_6	222534.KB893672_gene2959	9.963e-58	224.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria,4EWVP@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158416_k127_2617703_10	1121377.KB906398_gene2383	9.232e-53	188.0	2B5NQ@1|root,31YI3@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR25158416_k127_2617703_21	693986.MOC_3815	5.356e-11	66.0	2B5NQ@1|root,31YI3@2|Bacteria,1RH5V@1224|Proteobacteria,2U99Z@28211|Alphaproteobacteria,1JYX1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR25158416_k127_2617703_13	298655.KI912266_gene3965	1.969e-33	132.0	COG4276@1|root,COG4276@2|Bacteria,2ISSK@201174|Actinobacteria	201174|Actinobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_2617703_4	1499968.TCA2_4647	2.087e-67	233.0	arCOG11972@1|root,2ZG4P@2|Bacteria,1V2DB@1239|Firmicutes,4HN4N@91061|Bacilli,26UYX@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4166)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4166
SRR25158416_k127_2618868_26	479435.Kfla_4376	1.823e-17	88.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4DP5Q@85009|Propionibacteriales	201174|Actinobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158416_k127_2618868_29	58344.JOEL01000001_gene320	0.0002298	52.0	COG2353@1|root,COG2353@2|Bacteria,2GJFT@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,YceI
SRR25158416_k127_2618868_3	1306174.JODP01000013_gene7534	9.004e-287	891.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158416_k127_2618868_5	1380347.JNII01000005_gene2923	8.45e-190	604.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4ERCS@85013|Frankiales	201174|Actinobacteria	L	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158416_k127_2618868_6	469371.Tbis_2054	1.333e-173	554.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4DYW0@85010|Pseudonocardiales	201174|Actinobacteria	J	histidyl-tRNA synthetase	hisS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158416_k127_2618868_15	1184609.KILIM_012_00220	8.856e-92	307.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4F6S3@85018|Dermatophilaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_2618868_23	561175.KB894102_gene991	2.359e-49	186.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4EG67@85012|Streptosporangiales	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158416_k127_2618868_11	1120950.KB892708_gene4281	3.405e-135	449.0	COG1196@1|root,COG1196@2|Bacteria,2GJBD@201174|Actinobacteria,4DNC8@85009|Propionibacteriales	201174|Actinobacteria	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
SRR25158416_k127_2618868_0	1120950.KB892708_gene4280	0.0	1155.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4DNJH@85009|Propionibacteriales	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158416_k127_2618868_22	479435.Kfla_4399	9.663e-62	219.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4DQKV@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158416_k127_2618868_13	1120950.KB892708_gene4278	1.267e-101	348.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4DPBJ@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158416_k127_2618868_8	1120950.KB892708_gene4277	3.315e-165	537.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4DP94@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158416_k127_2618868_25	1246995.AFR_31055	3.934e-19	93.0	COG1862@1|root,COG1862@2|Bacteria,2IQSP@201174|Actinobacteria,4DFMC@85008|Micromonosporales	201174|Actinobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158416_k127_2618868_10	1120950.KB892708_gene4275	3.82e-162	519.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4DP63@85009|Propionibacteriales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158416_k127_2618868_18	58123.JOFJ01000017_gene4167	3.568e-70	244.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4EGZC@85012|Streptosporangiales	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158416_k127_2618868_21	1944.JOAZ01000007_gene2343	2.16e-65	228.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,418EB@629295|Streptomyces griseus group	201174|Actinobacteria	L	Crossover junction endodeoxyribonuclease RuvC	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158416_k127_2618868_12	1048339.KB913029_gene3939	1.698e-125	405.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4ES5T@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158416_k127_2618868_16	446466.Cfla_1792	7.137e-81	279.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4F231@85016|Cellulomonadaceae	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158416_k127_2618868_7	247156.NFA_37050	9.666e-171	541.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4FTYJ@85025|Nocardiaceae	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158416_k127_2618868_24	1463920.JOGB01000002_gene3097	3.64e-47	177.0	COG1704@1|root,COG1704@2|Bacteria,2GK54@201174|Actinobacteria	201174|Actinobacteria	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LemA
SRR25158416_k127_2618868_9	1120950.KB892708_gene4267	3.749e-163	523.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4DNV1@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158416_k127_2618868_14	67352.JODS01000020_gene4012	1.744e-95	326.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria	201174|Actinobacteria	M	Lipid A biosynthesis	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158416_k127_2618868_19	367299.JOEE01000008_gene523	3.399e-69	259.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4FF7D@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.11,2.7.8.5	ko:K00995,ko:K00999	ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070	-	R01801,R01802	RC00002,RC00017,RC00078,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158416_k127_2618868_1	1120950.KB892708_gene4264	0.0	1021.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4DNXI@85009|Propionibacteriales	201174|Actinobacteria	J	Elongation factor G, domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158416_k127_2618868_20	1123023.JIAI01000006_gene455	3.742e-67	238.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4DYSQ@85010|Pseudonocardiales	201174|Actinobacteria	FG	HIT family hydrolase, diadenosine tetraphosphate hydrolase	-	GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158416_k127_2618868_2	479435.Kfla_3362	1.102e-305	958.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4DN38@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158416_k127_2618868_4	1449347.JQLN01000005_gene4427	1.718e-208	659.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,2M4C5@2063|Kitasatospora	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158416_k127_2618868_28	33876.JNXY01000001_gene5829	3.906e-07	61.0	2FF2Y@1|root,34717@2|Bacteria,2GTPB@201174|Actinobacteria,4DFKD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2618868_17	110319.CF8_1856	1.582e-74	263.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4DNBK@85009|Propionibacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_2620916_13	1348663.KCH_51880	5.354e-23	102.0	COG1920@1|root,COG1920@2|Bacteria,2HJNU@201174|Actinobacteria,2M2UI@2063|Kitasatospora	201174|Actinobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158416_k127_2620916_8	1120950.KB892741_gene2696	2.69e-56	208.0	COG1920@1|root,COG1920@2|Bacteria,2HJNU@201174|Actinobacteria,4DRNC@85009|Propionibacteriales	201174|Actinobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158416_k127_2620916_6	1123320.KB889676_gene2895	3.705e-85	289.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_2620916_2	1463936.JOJI01000035_gene8032	2.641e-148	477.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158416_k127_2620916_4	479435.Kfla_4843	6.08e-135	440.0	COG0626@1|root,COG0626@2|Bacteria,2GMD8@201174|Actinobacteria,4DPBS@85009|Propionibacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158416_k127_2620916_3	590998.Celf_2451	1.314e-139	454.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4F0SC@85016|Cellulomonadaceae	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158416_k127_2620916_12	570268.ANBB01000022_gene5246	9.878e-24	112.0	2CQFE@1|root,32SM3@2|Bacteria,2GRVK@201174|Actinobacteria,4EKEN@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3515)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3515
SRR25158416_k127_2620916_9	479435.Kfla_4827	2.294e-36	139.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4DRPI@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158416_k127_2620916_5	1123320.KB889676_gene2890	3.207e-123	402.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR25158416_k127_2620916_10	1298880.AUEV01000006_gene4324	3.111e-30	119.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158416_k127_2620916_1	196162.Noca_3286	1.232e-159	519.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4DPSS@85009|Propionibacteriales	201174|Actinobacteria	S	Dak1_2	dak3	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158416_k127_2620916_0	67352.JODS01000026_gene3252	9.602e-274	861.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria	201174|Actinobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158416_k127_2620916_11	574966.KB898646_gene3248	1.204e-29	128.0	2A07X@1|root,30NB4@2|Bacteria,1N1WT@1224|Proteobacteria,1S9GH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
SRR25158416_k127_2620916_7	1283299.AUKG01000006_gene790	1.347e-65	226.0	COG2114@1|root,COG2114@2|Bacteria,2IDW7@201174|Actinobacteria,4CRAF@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
SRR25158416_k127_2627573_1	1120950.KB892746_gene3638	1.873e-162	513.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4DNW6@85009|Propionibacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158416_k127_2627573_4	351607.Acel_0335	2.956e-59	212.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4ESN1@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158416_k127_2627573_3	269800.Tfu_2616	4.595e-109	366.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4EHNP@85012|Streptosporangiales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158416_k127_2627573_5	469371.Tbis_1852	5.318e-10	65.0	2F46V@1|root,33WXW@2|Bacteria,2II56@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2627573_0	1298863.AUEP01000004_gene2120	4.958e-280	870.0	COG0488@1|root,COG0488@2|Bacteria,2GMUD@201174|Actinobacteria,4DNQ6@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158416_k127_2627573_2	512565.AMIS_40190	1.233e-113	372.0	COG0366@1|root,COG0366@2|Bacteria,2GKK1@201174|Actinobacteria,4DB3P@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
SRR25158416_k127_2633321_4	479435.Kfla_0630	2.615e-78	267.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4DQ84@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_2633321_0	1380393.JHVP01000020_gene227	4.658e-234	730.0	COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria,4EU6P@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158416_k127_2633321_1	1380393.JHVP01000020_gene228	7.864e-173	547.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4EUN8@85013|Frankiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_2633321_2	1380393.JHVP01000020_gene229	2.325e-113	373.0	COG1277@1|root,COG1277@2|Bacteria,2IQBJ@201174|Actinobacteria,4EVZU@85013|Frankiales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2633321_3	1453503.AU05_14180	4.681e-83	289.0	COG1063@1|root,COG1063@2|Bacteria,1MZ0B@1224|Proteobacteria,1RWKY@1236|Gammaproteobacteria,1YJE0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
SRR25158416_k127_2633321_5	1146883.BLASA_3324	9.628e-78	265.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ1@201174|Actinobacteria,4EUPE@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_2637286_7	981369.JQMJ01000004_gene5761	0.0006269	47.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,2NGD2@228398|Streptacidiphilus	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_2637286_4	55952.BU52_00370	4.207e-33	133.0	COG0346@1|root,COG0346@2|Bacteria,2IKKR@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_2637286_1	479432.Sros_8130	6.312e-117	386.0	COG1840@1|root,COG1840@2|Bacteria,2I33Y@201174|Actinobacteria,4EH1P@85012|Streptosporangiales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	phnS	-	-	ko:K02012,ko:K11081	ko02010,map02010	M00190,M00302	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.11.5	-	-	SBP_bac_11,SBP_bac_6
SRR25158416_k127_2637286_0	66874.JOFS01000005_gene4116	2.322e-173	563.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158416_k127_2637286_2	58123.JOFJ01000026_gene2710	2.955e-106	364.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EGCX@85012|Streptosporangiales	201174|Actinobacteria	E	TOBE domain	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158416_k127_2637286_3	1896.JOAU01000007_gene5662	3.678e-71	246.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158416_k127_2637286_5	710111.FraQA3DRAFT_1542	1.245e-29	125.0	COG0703@1|root,COG0703@2|Bacteria,2IQZ8@201174|Actinobacteria,4EW56@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158416_k127_2637286_6	1380370.JIBA01000016_gene942	3.149e-05	46.0	2CESF@1|root,2ZDIM@2|Bacteria,2HCW5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2645445_1	405948.SACE_0121	1.146e-234	736.0	COG4147@1|root,COG4147@2|Bacteria,2GJ56@201174|Actinobacteria,4DYB4@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158416_k127_2645445_7	521096.Tpau_1813	6.986e-32	130.0	COG3162@1|root,COG3162@2|Bacteria,2IQ5D@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
SRR25158416_k127_2645445_2	296591.Bpro_4151	1.32e-163	539.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,4AD1W@80864|Comamonadaceae	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SRR25158416_k127_2645445_5	187272.Mlg_0669	2.985e-44	165.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,1X2A5@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158416_k127_2645445_0	296591.Bpro_4149	0.0	1069.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
SRR25158416_k127_2645445_10	1454004.AW11_01101	0.000129	53.0	2DNR5@1|root,32YQH@2|Bacteria,1NBXJ@1224|Proteobacteria,2VW7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2645445_3	1122221.JHVI01000027_gene2830	1.497e-74	263.0	COG2905@1|root,COG2905@2|Bacteria,1WIBT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
SRR25158416_k127_2645445_6	1283287.KB822583_gene2826	1.099e-40	153.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4DN91@85009|Propionibacteriales	201174|Actinobacteria	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158416_k127_2645445_8	1122609.AUGT01000005_gene1932	2.788e-31	126.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,4DNMD@85009|Propionibacteriales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_2645445_4	196162.Noca_1253	1.247e-71	251.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,4DNMD@85009|Propionibacteriales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158416_k127_2645445_9	1370121.AUWS01000057_gene3670	2.992e-16	79.0	COG0277@1|root,COG0277@2|Bacteria,2GKQR@201174|Actinobacteria,2338V@1762|Mycobacteriaceae	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158416_k127_2659736_5	1043205.AFYF01000072_gene2217	4.814e-18	85.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4FF88@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_2659736_3	1032480.MLP_24350	2.297e-69	241.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4DPPI@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158416_k127_2659736_1	935866.JAER01000020_gene1550	5.233e-102	359.0	COG4412@1|root,COG4412@2|Bacteria,2I073@201174|Actinobacteria,4DW1Y@85009|Propionibacteriales	201174|Actinobacteria	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2659736_7	1121272.KB903250_gene3156	1.1e-14	88.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4DI10@85008|Micromonosporales	201174|Actinobacteria	S	Immune inhibitor A peptidase M6	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
SRR25158416_k127_2659736_2	101510.RHA1_ro02950	2.917e-93	310.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria,4FX2S@85025|Nocardiaceae	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158416_k127_2659736_0	479432.Sros_4198	6.102e-136	441.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4EJ1J@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158416_k127_2659736_6	710696.Intca_3056	1.682e-15	77.0	COG3237@1|root,COG3237@2|Bacteria,2HXWU@201174|Actinobacteria,4FI7C@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158416_k127_2659736_4	134676.ACPL_595	1.145e-37	145.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4D8J9@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRR25158416_k127_2671023_22	1043493.BBLU01000001_gene809	2.63e-05	52.0	2EVH6@1|root,33NXK@2|Bacteria,2H04P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2671023_13	1160137.KB907307_gene1742	2.553e-55	198.0	COG0563@1|root,COG0563@2|Bacteria,2IGX9@201174|Actinobacteria,4G25V@85025|Nocardiaceae	201174|Actinobacteria	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_33,SKI
SRR25158416_k127_2671023_17	1312954.KI914848_gene2058	1.846e-28	124.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2671023_3	743718.Isova_0344	6.707e-155	503.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4F3GI@85017|Promicromonosporaceae	201174|Actinobacteria	K	RNB	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158416_k127_2671023_8	1157637.KB892090_gene6265	6.733e-109	372.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria	201174|Actinobacteria	GL	phosphoglycerate mutase	-	-	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR25158416_k127_2671023_10	1449353.JQMQ01000005_gene4550	5.11e-67	238.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,2NIEH@228398|Streptacidiphilus	201174|Actinobacteria	S	C4-type zinc ribbon domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158416_k127_2671023_7	1048339.KB913029_gene4732	2.676e-139	456.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4ES0X@85013|Frankiales	201174|Actinobacteria	S	NIF3 (NGG1p interacting factor 3)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158416_k127_2671023_21	1172188.KB911823_gene647	1.424e-07	63.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FFQ2@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_2671023_19	1172188.KB911823_gene647	8.782e-17	87.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FFQ2@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_2671023_20	1172188.KB911823_gene647	2.974e-14	80.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FFQ2@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_2671023_16	1172188.KB911823_gene647	1.675e-30	124.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FFQ2@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_2671023_11	457429.ABJI02000612_gene2283	1.232e-57	212.0	COG3291@1|root,COG3291@2|Bacteria,2GKA0@201174|Actinobacteria	201174|Actinobacteria	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
SRR25158416_k127_2671023_4	1121272.KB903249_gene1622	6.508e-151	482.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4D92U@85008|Micromonosporales	201174|Actinobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158416_k127_2671023_9	469383.Cwoe_5365	1.371e-73	251.0	COG1309@1|root,COG1309@2|Bacteria,2IP03@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_2671023_12	469383.Cwoe_5364	1.244e-57	205.0	COG0346@1|root,COG0346@2|Bacteria,2GT35@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_2671023_14	1120950.KB892768_gene5259	1.322e-49	184.0	2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158416_k127_2671023_18	1206726.BAFV01000003_gene227	1.884e-21	98.0	COG2905@1|root,COG2905@2|Bacteria,2GQMA@201174|Actinobacteria,4G3WF@85025|Nocardiaceae	201174|Actinobacteria	T	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158416_k127_2671023_0	1121272.KB903253_gene6837	0.0	1461.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DABZ@85008|Micromonosporales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158416_k127_2671023_6	1120950.KB892768_gene5268	1.351e-139	460.0	COG3835@1|root,COG3835@2|Bacteria,2I2QR@201174|Actinobacteria,4DWX2@85009|Propionibacteriales	201174|Actinobacteria	KT	PucR C-terminal helix-turn-helix domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158416_k127_2671023_1	1122138.AQUZ01000004_gene930	3.138e-174	554.0	COG0331@1|root,COG0511@1|root,COG0331@2|Bacteria,COG0511@2|Bacteria,2GME0@201174|Actinobacteria,4DPZC@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl transferase domain	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158416_k127_2671023_5	196162.Noca_1989	9.843e-145	466.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4DP78@85009|Propionibacteriales	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158416_k127_2671023_15	1122138.AQUZ01000004_gene932	2.153e-34	134.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria,4DRYW@85009|Propionibacteriales	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158416_k127_2671023_2	1123322.KB904724_gene2087	1.942e-155	502.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158416_k127_2712654_2	390989.JOEG01000012_gene3452	2.49e-149	477.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4D8WS@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158416_k127_2712654_10	909613.UO65_0018	5.844e-62	228.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4E2WE@85010|Pseudonocardiales	201174|Actinobacteria	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158416_k127_2712654_12	1048339.KB913029_gene4333	1.305e-52	189.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4ESWH@85013|Frankiales	201174|Actinobacteria	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158416_k127_2712654_7	1120950.KB892708_gene4335	7.631e-84	284.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4DQIB@85009|Propionibacteriales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158416_k127_2712654_3	471852.Tcur_3000	3.19e-139	450.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4EHUK@85012|Streptosporangiales	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158416_k127_2712654_1	1003195.SCAT_5353	2.894e-179	572.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158416_k127_2712654_6	1120950.KB892708_gene4338	8.944e-99	327.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4DNZI@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158416_k127_2712654_4	397278.JOJN01000005_gene895	8.37e-128	419.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4DNKD@85009|Propionibacteriales	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016020,GO:0016070,GO:0034641,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158416_k127_2712654_9	561175.KB894098_gene5466	2.348e-74	259.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4EIPZ@85012|Streptosporangiales	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158416_k127_2712654_0	196162.Noca_2449	6.019e-185	586.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4DNA4@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158416_k127_2712654_11	1122622.ATWJ01000001_gene2528	1.933e-58	211.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4FGP5@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158416_k127_2712654_13	1048339.KB913029_gene4011	1.28e-28	123.0	COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4ETDD@85013|Frankiales	201174|Actinobacteria	E	Belongs to the PRA-PH family	hisE	GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
SRR25158416_k127_2712654_5	1120950.KB892707_gene4712	4.576e-124	407.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4DNZB@85009|Propionibacteriales	201174|Actinobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158416_k127_2712654_8	1048339.KB913029_gene3762	1.801e-82	277.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4ERZB@85013|Frankiales	201174|Actinobacteria	S	PFAM ATPase associated with various cellular activities AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158416_k127_2764374_0	1382306.JNIM01000001_gene2665	1.918e-82	288.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158416_k127_2764374_1	675635.Psed_6009	1.779e-27	117.0	COG1917@1|root,COG1917@2|Bacteria,2GYBD@201174|Actinobacteria,4EBKB@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_2771390_1	1120950.KB892707_gene4587	1.649e-71	247.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4DN8C@85009|Propionibacteriales	201174|Actinobacteria	KL	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRR25158416_k127_2771390_0	1120950.KB892707_gene4586	9.451e-275	859.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4DTZJ@85009|Propionibacteriales	201174|Actinobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158416_k127_2771390_3	1445613.JALM01000046_gene3116	0.0004003	48.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4E4UK@85010|Pseudonocardiales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158416_k127_2771390_2	35754.JNYJ01000008_gene3253	5.126e-06	52.0	COG1808@1|root,COG1808@2|Bacteria,2GJQ4@201174|Actinobacteria,4DA5U@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158416_k127_2772871_8	1095767.CAHD01000227_gene1038	1.598e-111	370.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4F0ED@85016|Cellulomonadaceae	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
SRR25158416_k127_2772871_12	1463856.JOHY01000025_gene3874	3.53e-57	204.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158416_k127_2772871_15	397278.JOJN01000001_gene2700	2.324e-32	128.0	COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4DRVC@85009|Propionibacteriales	201174|Actinobacteria	S	KH domain	-	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158416_k127_2772871_13	526226.Gbro_2083	6.631e-57	204.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4GDSV@85026|Gordoniaceae	201174|Actinobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158416_k127_2772871_5	1120950.KB892769_gene5396	1.387e-151	486.0	COG1228@1|root,COG1228@2|Bacteria,2GKRZ@201174|Actinobacteria,4DP0W@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158416_k127_2772871_2	1298863.AUEP01000002_gene1382	4.835e-226	711.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4DNUI@85009|Propionibacteriales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158416_k127_2772871_10	1449976.KALB_3452	9.796e-94	333.0	COG1028@1|root,COG1028@2|Bacteria,2H0SM@201174|Actinobacteria,4E07R@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158416_k127_2772871_14	436229.JOEH01000055_gene5664	3.249e-40	161.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria,2NIM1@228398|Streptacidiphilus	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_2772871_9	1449976.KALB_3449	4.817e-96	321.0	COG3327@1|root,COG3327@2|Bacteria,2GNME@201174|Actinobacteria,4E0B7@85010|Pseudonocardiales	201174|Actinobacteria	K	PaaX-like protein C-terminal domain	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
SRR25158416_k127_2772871_1	1449346.JQMO01000003_gene2538	1.425e-234	736.0	COG0365@1|root,COG0365@2|Bacteria,2GJVK@201174|Actinobacteria,2M4CB@2063|Kitasatospora	201174|Actinobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,AMP-binding,AMP-binding_C
SRR25158416_k127_2772871_4	405948.SACE_3133	1.763e-177	562.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria,4DZ7D@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_2772871_7	1449976.KALB_3436	3.661e-128	436.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA5	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158416_k127_2772871_0	405948.SACE_3134	0.0	1167.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4DXEE@85010|Pseudonocardiales	201174|Actinobacteria	CH	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
SRR25158416_k127_2772871_6	28444.JODQ01000001_gene2017	5.001e-130	423.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4EG5D@85012|Streptosporangiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158416_k127_2772871_3	2002.JOEQ01000024_gene48	1.528e-221	698.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4EFWU@85012|Streptosporangiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158416_k127_2772871_17	886293.Sinac_1369	5.113e-07	57.0	COG4747@1|root,COG4747@2|Bacteria,2J4QK@203682|Planctomycetes	203682|Planctomycetes	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2772871_11	1214101.BN159_1289	1.64e-86	292.0	COG2197@1|root,COG2197@2|Bacteria,2GN29@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_2772871_16	1380390.JIAT01000010_gene3697	1.614e-19	93.0	COG2199@1|root,COG4585@1|root,COG2199@2|Bacteria,COG4585@2|Bacteria,2IE6K@201174|Actinobacteria,4CR2U@84995|Rubrobacteria	84995|Rubrobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,PAS
SRR25158416_k127_2786949_3	196162.Noca_0658	5.064e-97	325.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4DPHZ@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_2786949_2	931627.MycrhDRAFT_1089	1.488e-102	347.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase_like
SRR25158416_k127_2786949_0	1075090.GOAMR_61_00210	7.838e-149	478.0	COG3173@1|root,COG3173@2|Bacteria,2H278@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_2786949_4	285535.JOEY01000007_gene8502	2.936e-47	176.0	2ECJT@1|root,336HX@2|Bacteria,2IKEF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2786949_1	1120950.KB892786_gene101	2.737e-128	413.0	COG1831@1|root,COG1831@2|Bacteria,2GM9F@201174|Actinobacteria,4DUV5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2787033_4	1385520.N802_13050	3.027e-22	103.0	2E1KX@1|root,32WYA@2|Bacteria,2I31X@201174|Actinobacteria	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158416_k127_2787033_3	909613.UO65_2225	6.634e-56	203.0	COG3467@1|root,COG3467@2|Bacteria,2GJ76@201174|Actinobacteria,4E32Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158416_k127_2787033_0	1077972.ARGLB_092_00100	1.654e-88	310.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,1W91D@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158416_k127_2787033_1	1380347.JNII01000007_gene756	1.535e-81	285.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.23.1.1,1.23.1.2,1.23.1.3,1.23.1.4	ko:K21568	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_10,NmrA
SRR25158416_k127_2787033_2	1121924.ATWH01000004_gene2286	2.543e-62	224.0	COG1672@1|root,COG2197@1|root,COG1672@2|Bacteria,COG2197@2|Bacteria,2I3SK@201174|Actinobacteria,4FRS0@85023|Microbacteriaceae	201174|Actinobacteria	KT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_2790509_13	1449976.KALB_2204	5.033e-102	338.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DZ0A@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158416_k127_2790509_6	653045.Strvi_4192	2.23e-147	484.0	COG1879@1|root,COG1879@2|Bacteria,2GN16@201174|Actinobacteria	201174|Actinobacteria	K	LacI family transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
SRR25158416_k127_2790509_1	1306990.BARG01000024_gene2699	1.73e-239	747.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158416_k127_2790509_0	1306990.BARG01000024_gene2452	1.062e-316	980.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the TPP enzyme family	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158416_k127_2790509_12	1440053.JOEI01000029_gene4463	2.763e-108	360.0	COG3836@1|root,COG3836@2|Bacteria,2IE8J@201174|Actinobacteria	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158416_k127_2790509_2	1386089.N865_15190	2.132e-193	614.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4FEVC@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_2790509_8	1440053.JOEI01000029_gene4461	5.656e-130	430.0	COG1052@1|root,COG1052@2|Bacteria,2I869@201174|Actinobacteria	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158416_k127_2790509_10	1463853.JOHW01000014_gene298	5.443e-122	398.0	COG1028@1|root,COG1028@2|Bacteria,2H1EB@201174|Actinobacteria	201174|Actinobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158416_k127_2790509_4	1463861.JNXE01000004_gene1738	4.295e-155	495.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_2790509_7	1440053.JOEI01000029_gene4460	6.71e-139	447.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria	201174|Actinobacteria	G	dehydratase	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_2790509_5	1157637.KB892108_gene4560	7.213e-149	481.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_2790509_9	1218074.BAXZ01000013_gene2923	1.099e-124	406.0	COG1028@1|root,COG1028@2|Bacteria,1MUWC@1224|Proteobacteria,2W95J@28216|Betaproteobacteria,1K97M@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_2790509_11	345341.KUTG_08045	1.15e-118	392.0	COG0500@1|root,COG2226@2|Bacteria,2I3SA@201174|Actinobacteria,4EF8K@85010|Pseudonocardiales	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158416_k127_2790509_3	1394178.AWOO02000013_gene7948	1.358e-173	550.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4EK4C@85012|Streptosporangiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158416_k127_2790509_14	1120949.KB903295_gene2334	8.781e-30	119.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158416_k127_2791776_15	1121877.JQKF01000057_gene118	9.598e-06	49.0	COG3464@1|root,COG3464@2|Bacteria,2GYV8@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
SRR25158416_k127_2791776_8	1306990.BARG01000038_gene4472	6.781e-31	132.0	COG2259@1|root,COG2259@2|Bacteria,2IJ0I@201174|Actinobacteria	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158416_k127_2791776_6	1380347.JNII01000011_gene1034	8.316e-39	151.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158416_k127_2791776_11	324602.Caur_3769	5.285e-19	98.0	COG2152@1|root,COG3055@1|root,COG3266@1|root,COG5624@1|root,COG2152@2|Bacteria,COG3055@2|Bacteria,COG3266@2|Bacteria,COG5624@2|Bacteria,2G86G@200795|Chloroflexi,376E1@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158416_k127_2791776_16	55952.BU52_03560	0.0005322	47.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_2791776_12	55952.BU52_03560	5.244e-16	81.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_2791776_14	110319.CF8_3429	2.84e-12	74.0	2DMFH@1|root,32R60@2|Bacteria,2IP6I@201174|Actinobacteria,4DSGD@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2791776_9	1056816.JAFQ01000003_gene7218	2.262e-29	120.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4FVG2@85025|Nocardiaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_2791776_4	1236902.ANAS01000044_gene2186	2.662e-47	176.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4EFNU@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_2791776_13	1115803.HMPREF1129_1669	2.266e-12	74.0	2E3WU@1|root,31I5Y@2|Bacteria,2HMNS@201174|Actinobacteria,4D7BA@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2791776_7	479431.Namu_2560	3.782e-37	151.0	COG2801@1|root,COG2801@2|Bacteria,2IEHA@201174|Actinobacteria,4EUPG@85013|Frankiales	201174|Actinobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
SRR25158416_k127_2791776_0	296591.Bpro_3020	0.0	1586.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2VKIR@28216|Betaproteobacteria	28216|Betaproteobacteria	E	NAD-glutamate dehydrogenase	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158416_k127_2791776_5	1038860.AXAP01000038_gene3746	3.411e-43	177.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U3XH@28211|Alphaproteobacteria,3JUYR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,HemolysinCabind
SRR25158416_k127_2791776_10	1283283.ATXA01000019_gene2945	1.372e-24	105.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_2791776_2	1283283.ATXA01000005_gene2208	6.931e-69	246.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4EWWQ@85013|Frankiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_2791776_1	570268.ANBB01000004_gene135	5.524e-89	307.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EMXE@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158416_k127_2791776_3	1380390.JIAT01000003_gene5448	2.314e-48	176.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria,4CPYH@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_2793004_3	1123013.AUIC01000002_gene1177	2.046e-66	231.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4FNDD@85023|Microbacteriaceae	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158416_k127_2793004_1	1211815.CBYP010000046_gene898	1.96e-95	323.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4ERZ1@85013|Frankiales	201174|Actinobacteria	J	TIGRFAM methionine aminopeptidase, type I	mapA	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158416_k127_2793004_7	1120950.KB892746_gene3633	1.862e-34	138.0	COG4758@1|root,COG4758@2|Bacteria,2HP3B@201174|Actinobacteria,4DSH5@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR25158416_k127_2793004_6	408672.NBCG_03662	3.229e-40	153.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4DRMG@85009|Propionibacteriales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158416_k127_2793004_8	471853.Bcav_3116	1.054e-15	81.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158416_k127_2793004_4	351607.Acel_0331	1.037e-62	219.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4ESIQ@85013|Frankiales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158416_k127_2793004_2	67352.JODS01000006_gene6484	5.586e-69	236.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158416_k127_2793004_0	196162.Noca_3876	2.082e-99	327.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4DP75@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158416_k127_2793004_5	281090.Lxx20080	1.166e-43	160.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4FM7X@85023|Microbacteriaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158416_k127_2801046_4	285535.JOEY01000013_gene4675	2.635e-45	169.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_2801046_5	468556.AQYG01000046_gene1203	6.397e-24	101.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4GDRA@85026|Gordoniaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158416_k127_2801046_0	710687.KI912270_gene3269	2.841e-101	336.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,2377M@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158416_k127_2801046_2	1120949.KB903312_gene654	2.361e-54	194.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158416_k127_2801046_3	479431.Namu_3045	4.017e-52	190.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158416_k127_2801046_1	479431.Namu_3669	5.112e-82	276.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158416_k127_2815334_6	1869.MB27_11625	2.171e-24	106.0	COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria,4DDXG@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158416_k127_2815334_3	1206739.BAGJ01000058_gene5167	3.916e-76	267.0	COG1511@1|root,COG1511@2|Bacteria,2HEUW@201174|Actinobacteria,4FXKD@85025|Nocardiaceae	201174|Actinobacteria	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2815334_5	1157640.AQWO01000024_gene1621	8.329e-54	199.0	COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158416_k127_2815334_2	1173264.KI913949_gene1673	2.672e-107	366.0	COG0405@1|root,COG0405@2|Bacteria,1G20A@1117|Cyanobacteria,1H8BE@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158416_k127_2815334_1	1120950.KB892790_gene2100	1.299e-180	575.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4DMZ8@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158416_k127_2815334_4	1121324.CLIT_2c03230	7.467e-64	229.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
SRR25158416_k127_2815334_7	110319.CF8_4099	1.432e-21	98.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158416_k127_2815334_0	1033730.CAHG01000008_gene3124	4.791e-245	766.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DN2S@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158416_k127_2842410_5	479435.Kfla_0909	3.286e-60	211.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4DNF9@85009|Propionibacteriales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158416_k127_2842410_1	1386089.N865_18785	9.263e-112	367.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4FIGZ@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158416_k127_2842410_4	561175.KB894095_gene2259	4.621e-67	233.0	COG0500@1|root,COG2226@2|Bacteria,2I36Q@201174|Actinobacteria,4EP4K@85012|Streptosporangiales	201174|Actinobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158416_k127_2842410_8	1298863.AUEP01000005_gene2451	3.207e-27	116.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4DS3V@85009|Propionibacteriales	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158416_k127_2842410_6	675635.Psed_3415	2.389e-51	184.0	2CNY9@1|root,31GEE@2|Bacteria,2IKKZ@201174|Actinobacteria,4E4N7@85010|Pseudonocardiales	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158416_k127_2842410_2	58123.JOFJ01000006_gene158	1.458e-108	358.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4EH59@85012|Streptosporangiales	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158416_k127_2842410_3	103733.JNYO01000026_gene8843	3.244e-104	363.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4E0XZ@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Glucose-6-phosphate dehydrogenase subunit	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158416_k127_2842410_0	1095767.CAHD01000213_gene585	9.297e-278	861.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4F0EX@85016|Cellulomonadaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158416_k127_2842410_7	1312954.KI914877_gene1118	8.322e-48	173.0	COG0166@1|root,COG0166@2|Bacteria,2HT2Q@201174|Actinobacteria,1W8PK@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158416_k127_2844644_1	266117.Rxyl_2343	5.823e-101	338.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,4CPS7@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158416_k127_2844644_0	931627.MycrhDRAFT_0013	5.074e-162	522.0	COG0277@1|root,COG0277@2|Bacteria,2GKQR@201174|Actinobacteria,2338V@1762|Mycobacteriaceae	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158416_k127_2859629_0	43759.JNWK01000053_gene2881	3.687e-120	391.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158416_k127_2859629_2	1449048.JQKU01000031_gene2927	1.365e-17	90.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,236CE@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158416_k127_2859629_1	1123024.AUII01000036_gene3135	1.148e-28	119.0	COG1597@1|root,COG1597@2|Bacteria,2GNNM@201174|Actinobacteria,4E66K@85010|Pseudonocardiales	201174|Actinobacteria	G	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158416_k127_2860427_3	1380393.JHVP01000012_gene2813	2.674e-24	108.0	COG4319@1|root,COG4319@2|Bacteria,2IIFR@201174|Actinobacteria,4ETHE@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158416_k127_2860427_2	68170.KL590489_gene10411	3.556e-43	160.0	2C56A@1|root,32RF5@2|Bacteria,2IP97@201174|Actinobacteria,4E5EJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158416_k127_2860427_1	28444.JODQ01000006_gene545	8.48e-45	170.0	COG2227@1|root,COG2227@2|Bacteria,2GTJX@201174|Actinobacteria,4EJSA@85012|Streptosporangiales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158416_k127_2860427_0	222534.KB893717_gene1959	4.206e-67	238.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_2862391_8	469383.Cwoe_0891	3.93e-08	58.0	COG0671@1|root,COG0671@2|Bacteria,2IIA1@201174|Actinobacteria,4CQUT@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158416_k127_2862391_1	1120949.KB903328_gene9117	5.438e-64	226.0	COG3247@1|root,COG3247@2|Bacteria,2GSMH@201174|Actinobacteria,4DFMZ@85008|Micromonosporales	201174|Actinobacteria	S	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158416_k127_2862391_7	1122609.AUGT01000009_gene3046	6.279e-09	59.0	COG2909@1|root,COG3284@1|root,COG2909@2|Bacteria,COG3284@2|Bacteria	2|Bacteria	KQ	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HTH_8,Sulfotransfer_3,TPR_16,TPR_19
SRR25158416_k127_2862391_9	1172186.KB911467_gene2026	1.662e-07	60.0	COG4420@1|root,COG4420@2|Bacteria,2INCC@201174|Actinobacteria,239CT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158416_k127_2862391_6	710686.Mycsm_03648	8.277e-17	89.0	COG4420@1|root,COG4420@2|Bacteria,2INCC@201174|Actinobacteria,239CT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158416_k127_2862391_4	591158.SSMG_06260	7.104e-22	109.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K16029	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH
SRR25158416_k127_2862391_0	1068978.AMETH_6087	1.266e-88	300.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K16029	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH
SRR25158416_k127_2862391_3	526225.Gobs_2383	7.026e-25	109.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria,4EVDX@85013|Frankiales	201174|Actinobacteria	I	TAP-like protein	-	-	3.1.1.76	ko:K22250	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158416_k127_2862391_5	471853.Bcav_0362	1.805e-20	98.0	COG1277@1|root,COG1277@2|Bacteria,2IRIX@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158416_k127_2865892_0	1298863.AUEP01000013_gene4038	1.766e-171	549.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DNN2@85009|Propionibacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158416_k127_2865892_5	290397.Adeh_1080	1.907e-06	53.0	2AG1H@1|root,3165K@2|Bacteria,1NGEK@1224|Proteobacteria	1224|Proteobacteria	S	Pfam:DUF1602	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2865892_1	1380390.JIAT01000010_gene4957	1.773e-130	427.0	COG0845@1|root,COG0845@2|Bacteria,2IH5S@201174|Actinobacteria,4CP8J@84995|Rubrobacteria	84995|Rubrobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2865892_4	1298863.AUEP01000013_gene4041	8.865e-51	190.0	2EBG5@1|root,335GQ@2|Bacteria,2GRUT@201174|Actinobacteria,4DSMC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2865892_3	469383.Cwoe_1418	8.005e-80	273.0	COG1876@1|root,COG1876@2|Bacteria,2IHUG@201174|Actinobacteria,4CQJR@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
SRR25158416_k127_2865892_2	1137269.AZWL01000006_gene6725	2.105e-88	292.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K18352	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_2887778_3	1125971.ASJB01000057_gene5197	2.451e-18	89.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4E222@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_2887778_4	1120950.KB892814_gene6934	4.779e-12	71.0	COG2267@1|root,COG2267@2|Bacteria,2I1RU@201174|Actinobacteria,4DR9Z@85009|Propionibacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_2887778_0	1120950.KB892778_gene1035	1.193e-108	360.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4DP1Y@85009|Propionibacteriales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_2887778_2	1459636.NTE_00536	9.182e-21	101.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158416_k127_2887778_1	446469.Sked_07750	1.036e-37	149.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_2915925_10	28444.JODQ01000001_gene2645	2.576e-37	141.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4EG5E@85012|Streptosporangiales	201174|Actinobacteria	V	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158416_k127_2915925_7	1304865.JAGF01000001_gene3751	4.625e-87	298.0	COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,4F29Z@85016|Cellulomonadaceae	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	gluD	-	-	ko:K10007	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
SRR25158416_k127_2915925_8	1120950.KB892756_gene6700	9.916e-84	284.0	COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4DR1N@85009|Propionibacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	gluC	-	-	ko:K10006,ko:K10040	ko02010,map02010	M00228,M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.9	-	-	BPD_transp_1
SRR25158416_k127_2915925_3	1120950.KB892756_gene6701	1.941e-125	407.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4DPUC@85009|Propionibacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	gluB	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
SRR25158416_k127_2915925_4	1304865.JAGF01000001_gene3748	1.916e-122	397.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4F10P@85016|Cellulomonadaceae	201174|Actinobacteria	E	PFAM ABC transporter related	gluA	-	-	ko:K10008	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.9	-	-	ABC_tran
SRR25158416_k127_2915925_0	1122138.AQUZ01000043_gene3320	6.599e-236	742.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4DNBY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158416_k127_2915925_9	1463881.KL591012_gene4966	6.589e-62	220.0	COG3885@1|root,COG3885@2|Bacteria,2GN3T@201174|Actinobacteria	201174|Actinobacteria	S	ferrous iron binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2915925_2	1122138.AQUZ01000043_gene3314	8.596e-127	412.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4DP56@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158416_k127_2915925_6	1003195.SCAT_4565	8.16e-88	299.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158416_k127_2915925_1	390989.JOEG01000005_gene1791	9.157e-203	643.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4D8FD@85008|Micromonosporales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158416_k127_2915925_5	996637.SGM_3141	4.718e-90	304.0	COG1808@1|root,COG1808@2|Bacteria,2GJQ4@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158416_k127_2916722_1	1120950.KB892760_gene5724	8.541e-146	467.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4DP1R@85009|Propionibacteriales	201174|Actinobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158416_k127_2916722_0	1246995.AFR_05125	1.542e-158	512.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4DC08@85008|Micromonosporales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158416_k127_2916722_2	644283.Micau_5381	5.075e-123	404.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4D97E@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158416_k127_2929383_5	1298863.AUEP01000005_gene2431	3.878e-123	417.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4DNC0@85009|Propionibacteriales	201174|Actinobacteria	O	assembly ATPase	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158416_k127_2929383_4	1179773.BN6_62320	1.258e-140	458.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4DXG3@85010|Pseudonocardiales	201174|Actinobacteria	O	TIGRFAM FeS assembly protein SufD	sufD	GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158416_k127_2929383_1	1120950.KB892707_gene4650	4.825e-284	875.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4DN7B@85009|Propionibacteriales	201174|Actinobacteria	O	Uncharacterized protein family (UPF0051)	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158416_k127_2929383_7	1048339.KB913029_gene4339	3.601e-88	298.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4ESM6@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SRR25158416_k127_2929383_8	397278.JOJN01000004_gene1369	2.847e-80	278.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4DQ6X@85009|Propionibacteriales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158416_k127_2929383_9	443255.SCLAV_1130	7.374e-08	62.0	2ER41@1|root,33IPK@2|Bacteria,2IKQ6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2929383_6	1184609.KILIM_005_00900	1.744e-96	324.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4F6J4@85018|Dermatophilaceae	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158416_k127_2929383_0	479435.Kfla_3272	0.0	1044.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4DN1Y@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158416_k127_2929383_3	471857.Svir_15970	4.128e-142	464.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DXR6@85010|Pseudonocardiales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158416_k127_2929383_2	1122138.AQUZ01000001_gene1576	1.783e-162	523.0	COG0166@1|root,COG0166@2|Bacteria,2HZ58@201174|Actinobacteria,4DN42@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the GPI family	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158416_k127_2935515_3	298654.FraEuI1c_5114	1.147e-81	282.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4EV93@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_2935515_9	1306990.BARG01000014_gene1348	2.269e-09	63.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_2935515_2	365528.KB891262_gene5081	6.746e-83	289.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4ERBK@85013|Frankiales	201174|Actinobacteria	K	regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_2935515_1	1306990.BARG01000052_gene6289	1.937e-104	359.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_2935515_0	448385.sce8942	1.245e-134	444.0	2AN7A@1|root,31D59@2|Bacteria,1QA8J@1224|Proteobacteria,434WM@68525|delta/epsilon subdivisions,2WZ7J@28221|Deltaproteobacteria,2Z1I2@29|Myxococcales	28221|Deltaproteobacteria	C	Common central domain of tyrosinase	-	-	-	-	-	-	-	-	-	-	-	-	Tyrosinase
SRR25158416_k127_2935515_8	467200.ACFA01000377_gene400	1.575e-11	70.0	COG0286@1|root,COG1002@1|root,COG0286@2|Bacteria,COG1002@2|Bacteria	2|Bacteria	V	DNA modification	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158416_k127_2935515_4	381666.H16_B2403	3.715e-40	160.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2VI5K@28216|Betaproteobacteria,1K8C3@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Eukaryotic-type carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase,VPEP
SRR25158416_k127_2935515_7	477641.MODMU_1119	1.388e-13	76.0	COG2329@1|root,COG2329@2|Bacteria,2IQBH@201174|Actinobacteria,4EWB0@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158416_k127_2935515_5	1122611.KB903946_gene830	9.803e-24	109.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria,4EHT5@85012|Streptosporangiales	201174|Actinobacteria	Q	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_2
SRR25158416_k127_2935515_6	1464048.JNZS01000017_gene3671	6.301e-14	83.0	COG0406@1|root,COG0494@1|root,COG0406@2|Bacteria,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4DB83@85008|Micromonosporales	201174|Actinobacteria	GL	Nudix hydrolase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158416_k127_2937130_2	477641.MODMU_5043	2.073e-26	120.0	COG5640@1|root,COG5640@2|Bacteria,2IB3X@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158416_k127_2937130_0	1122138.AQUZ01000039_gene8018	7.651e-98	331.0	COG3386@1|root,COG3386@2|Bacteria,2HDRT@201174|Actinobacteria,4DNUM@85009|Propionibacteriales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158416_k127_2937130_1	1246995.AFR_22595	4.526e-46	169.0	COG0346@1|root,COG0346@2|Bacteria,2IHX4@201174|Actinobacteria,4DFUI@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_2937130_3	1089545.KB913037_gene8701	0.0002654	48.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E4JX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_2948338_3	2074.JNYD01000003_gene3916	1.054e-43	163.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4DZM8@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_2948338_1	1386089.N865_00470	4.05e-159	507.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4FID4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_2948338_2	1032480.MLP_32140	6.281e-128	417.0	COG3622@1|root,COG3622@2|Bacteria,2GKPC@201174|Actinobacteria,4DR0F@85009|Propionibacteriales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_2948338_0	1385519.N801_04090	0.0	1395.0	COG0358@1|root,COG0507@1|root,COG0358@2|Bacteria,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4FEDX@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA primase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,Toprim_2,Toprim_N,TrwC
SRR25158416_k127_2948338_4	1042876.PPS_1780	2.529e-18	89.0	COG2159@1|root,COG2159@2|Bacteria,1R8PV@1224|Proteobacteria,1S8J0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
SRR25158416_k127_2957057_2	390989.JOEG01000025_gene65	7.23e-125	404.0	COG2318@1|root,COG2318@2|Bacteria,2I3S3@201174|Actinobacteria,4DMJ0@85008|Micromonosporales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Pentapeptide
SRR25158416_k127_2957057_8	1380356.JNIK01000005_gene1044	3.188e-11	70.0	2BCV5@1|root,326FU@2|Bacteria,2HBXJ@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2957057_1	1157637.KB892135_gene3543	1.094e-134	437.0	COG1485@1|root,COG1485@2|Bacteria,2GNQA@201174|Actinobacteria	201174|Actinobacteria	S	PFAM AFG1-family ATPase	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
SRR25158416_k127_2957057_3	1348663.KCH_55580	2.393e-66	238.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,2M117@2063|Kitasatospora	201174|Actinobacteria	H	RibD C-terminal domain	-	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158416_k127_2957057_0	590998.Celf_2588	1.656e-181	575.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4F29M@85016|Cellulomonadaceae	201174|Actinobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158416_k127_2957057_5	1120950.KB892748_gene3264	1.439e-42	162.0	2AQ7N@1|root,31FDD@2|Bacteria,2IFXR@201174|Actinobacteria,4DRWQ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2957057_6	391037.Sare_1132	3.16e-34	136.0	COG3861@1|root,COG3861@2|Bacteria,2IQ4Y@201174|Actinobacteria,4DEHC@85008|Micromonosporales	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2957057_7	1123065.ATWL01000011_gene92	2.978e-24	109.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_2957057_9	1123065.ATWL01000011_gene92	9.454e-11	68.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_2957057_11	1120949.KB903304_gene6980	1.301e-06	51.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_primase_S
SRR25158416_k127_2957057_10	1211815.CBYP010000069_gene1420	3.603e-09	64.0	2EQSQ@1|root,33ICI@2|Bacteria,2GPJ1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2957057_4	1394178.AWOO02000013_gene7934	3.508e-57	214.0	COG1522@1|root,COG1522@2|Bacteria,2GNCB@201174|Actinobacteria	201174|Actinobacteria	K	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2968603_11	1380347.JNII01000006_gene1592	3.162e-37	145.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158416_k127_2968603_3	497964.CfE428DRAFT_0631	1.954e-152	516.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158416_k127_2968603_10	1068980.ARVW01000001_gene1387	1.761e-57	207.0	COG1514@1|root,COG1514@2|Bacteria,2GPPG@201174|Actinobacteria,4E60Y@85010|Pseudonocardiales	201174|Actinobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2968603_7	1385521.N803_04950	2.116e-92	316.0	COG0451@1|root,COG0451@2|Bacteria,2GN90@201174|Actinobacteria,4FJXP@85021|Intrasporangiaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_2968603_9	1095767.CAHD01000068_gene3061	7.493e-71	244.0	COG2606@1|root,COG2606@2|Bacteria,2IIIW@201174|Actinobacteria,4F1D0@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158416_k127_2968603_4	1449976.KALB_6164	1.886e-127	415.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria,4E2B4@85010|Pseudonocardiales	201174|Actinobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158416_k127_2968603_12	253839.SSNG_01313	5.019e-13	72.0	2EP6A@1|root,33GT0@2|Bacteria,2GQTX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2968603_6	1122138.AQUZ01000001_gene1515	1.575e-104	351.0	COG1162@1|root,COG1162@2|Bacteria,2GMDX@201174|Actinobacteria	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158416_k127_2968603_1	1120950.KB892708_gene4216	9.487e-209	665.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4DN98@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158416_k127_2968603_0	103733.JNYO01000002_gene538	5.675e-272	847.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4DZSG@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	sir	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158416_k127_2968603_13	68570.DC74_6299	7.549e-13	70.0	COG3677@1|root,COG3677@2|Bacteria,2GQKE@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2968603_8	68223.JNZY01000004_gene3788	2.436e-84	290.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158416_k127_2968603_2	590998.Celf_2118	7.443e-157	509.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,4F0HX@85016|Cellulomonadaceae	201174|Actinobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cysG	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
SRR25158416_k127_2968603_5	1122138.AQUZ01000001_gene1529	4.267e-118	388.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4DNFS@85009|Propionibacteriales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158416_k127_2969793_0	67352.JODS01000003_gene2049	7.544e-19	97.0	COG3409@1|root,COG3409@2|Bacteria,2HB3I@201174|Actinobacteria	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1
SRR25158416_k127_2969793_2	4538.ORGLA02G0139700.1	0.0002146	49.0	COG0542@1|root,KOG1051@2759|Eukaryota,37MFF@33090|Viridiplantae,3GFJ7@35493|Streptophyta,3M3W2@4447|Liliopsida,3IDJH@38820|Poales	35493|Streptophyta	O	vascular transport	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0009507,GO:0009536,GO:0010232,GO:0010233,GO:0032501,GO:0033500,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0065007,GO:0065008	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR25158416_k127_2969793_1	749414.SBI_08715	0.0001857	44.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158416_k127_2974653_6	1120950.KB892759_gene6286	1.046e-137	462.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4DN93@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158416_k127_2974653_15	1048339.KB913029_gene5102	1.803e-45	183.0	COG3147@1|root,COG3147@2|Bacteria,2HC8A@201174|Actinobacteria,4EVYP@85013|Frankiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2974653_17	266940.Krad_3844	1.081e-39	152.0	COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158416_k127_2974653_14	479435.Kfla_1593	7.075e-48	176.0	2C7XW@1|root,32RR4@2|Bacteria,2IQ5R@201174|Actinobacteria,4DRSS@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3499
SRR25158416_k127_2974653_1	1122138.AQUZ01000028_gene738	4.066e-198	626.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4DPGJ@85009|Propionibacteriales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158416_k127_2974653_18	397278.JOJN01000007_gene3233	3.98e-20	90.0	COG2835@1|root,COG2835@2|Bacteria,2HUT7@201174|Actinobacteria,4DSPV@85009|Propionibacteriales	201174|Actinobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158416_k127_2974653_8	1120950.KB892759_gene6293	5.249e-96	327.0	COG1737@1|root,COG1737@2|Bacteria,2GMG0@201174|Actinobacteria,4DMZS@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
SRR25158416_k127_2974653_9	68260.JOAY01000047_gene862	9.154e-90	310.0	COG1482@1|root,COG1482@2|Bacteria,2GJXC@201174|Actinobacteria	201174|Actinobacteria	G	mannose-6-phosphate isomerase	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
SRR25158416_k127_2974653_7	369723.Strop_0964	2.525e-121	398.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4DAPD@85008|Micromonosporales	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158416_k127_2974653_0	269800.Tfu_2505	3.128e-264	818.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4EIAX@85012|Streptosporangiales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158416_k127_2974653_12	2002.JOEQ01000004_gene3011	3.41e-64	232.0	COG1714@1|root,COG1714@2|Bacteria,2H4MP@201174|Actinobacteria,4EIUF@85012|Streptosporangiales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158416_k127_2974653_5	1157637.KB892102_gene1235	2.864e-144	467.0	COG1300@1|root,COG1300@2|Bacteria,2GJTG@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158416_k127_2974653_2	287986.DV20_25830	7.506e-174	554.0	COG1721@1|root,COG1721@2|Bacteria,2GK9A@201174|Actinobacteria,4DXK9@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
SRR25158416_k127_2974653_4	1463820.JOGW01000007_gene2108	6.118e-156	512.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria	201174|Actinobacteria	S	associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158416_k127_2974653_10	67352.JODS01000010_gene4958	1.715e-82	290.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158416_k127_2974653_16	446466.Cfla_2334	1.668e-40	161.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria,4F1G4@85016|Cellulomonadaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158416_k127_2974653_11	711393.AYRX01000018_gene3187	2.601e-66	243.0	COG4223@1|root,COG4223@2|Bacteria,2I390@201174|Actinobacteria	201174|Actinobacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158416_k127_2974653_3	463191.SSEG_10917	3.929e-170	553.0	COG5002@1|root,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158416_k127_2974653_13	1120950.KB892764_gene5596	8.916e-63	236.0	COG5401@1|root,COG5401@2|Bacteria,2GJ5Y@201174|Actinobacteria,4DQ1Z@85009|Propionibacteriales	201174|Actinobacteria	M	Sporulation and spore germination	lpqB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Germane,Gmad1
SRR25158416_k127_2985754_7	1120950.KB892717_gene2440	9.868e-113	381.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4DPV3@85009|Propionibacteriales	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158416_k127_2985754_6	1380347.JNII01000006_gene1956	3.14e-113	373.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4EVBE@85013|Frankiales	201174|Actinobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158416_k127_2985754_17	1120950.KB892739_gene3913	1.934e-46	169.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4DVII@85009|Propionibacteriales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158416_k127_2985754_8	1108045.GORHZ_245_00600	3.908e-104	341.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4GGZI@85026|Gordoniaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158416_k127_2985754_13	1214101.BN159_4714	3.356e-72	255.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,LMWPc
SRR25158416_k127_2985754_9	1122939.ATUD01000008_gene2443	2.466e-101	337.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4CQ49@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158416_k127_2985754_19	1449976.KALB_5607	4.899e-41	154.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4E4AY@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158416_k127_2985754_16	1137268.AZXF01000012_gene3592	9.246e-48	173.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4EQ8P@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158416_k127_2985754_0	1240349.ANGC01000051_gene4101	1.639e-177	569.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria,4FVE9@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2985754_2	1449346.JQMO01000002_gene1590	1.694e-135	436.0	COG2227@1|root,COG2227@2|Bacteria,2I387@201174|Actinobacteria,2M3Q9@2063|Kitasatospora	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158416_k127_2985754_20	502025.Hoch_1265	1.337e-36	149.0	COG3832@1|root,COG3832@2|Bacteria,1QZTB@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_2985754_5	1160137.KB907309_gene5836	1.369e-115	384.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4G75H@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_2985754_15	1120949.KB903295_gene2443	1.04e-50	188.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4DJN3@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_2985754_4	485913.Krac_6018	4.692e-116	382.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158416_k127_2985754_26	1276920.ADIAG_02011	2.883e-07	58.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria,1WCFZ@1268|Micrococcaceae	201174|Actinobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158416_k127_2985754_23	367299.JOEE01000001_gene2035	3.276e-23	107.0	2EHZA@1|root,33BQS@2|Bacteria,2IJZ0@201174|Actinobacteria,4FGP6@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2985754_11	1048339.KB913029_gene3828	1.973e-87	297.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4ETG1@85013|Frankiales	201174|Actinobacteria	GK	PFAM ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158416_k127_2985754_10	1120950.KB892812_gene7005	1.467e-92	311.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4DNQW@85009|Propionibacteriales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158416_k127_2985754_21	1907.SGLAU_17515	6.902e-36	143.0	COG0746@1|root,COG0746@2|Bacteria,2GJVE@201174|Actinobacteria	201174|Actinobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRR25158416_k127_2985754_24	1214242.B446_19420	1.353e-19	91.0	COG0746@1|root,COG0746@2|Bacteria,2GJVE@201174|Actinobacteria	201174|Actinobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRR25158416_k127_2985754_3	1120950.KB892812_gene7002	6.912e-123	415.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria,4DPPQ@85009|Propionibacteriales	201174|Actinobacteria	P	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
SRR25158416_k127_2985754_1	749414.SBI_05435	1.233e-141	456.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria	201174|Actinobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158416_k127_2985754_14	471853.Bcav_2097	3.525e-71	252.0	COG0524@1|root,COG0524@2|Bacteria,2I8KP@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158416_k127_2985754_12	33876.JNXY01000028_gene3272	3.705e-78	298.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
SRR25158416_k127_2985754_25	216594.MMAR_1794	1.342e-15	93.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria,2334C@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknI	GO:0003674,GO:0003824,GO:0004672,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019538,GO:0030145,GO:0036211,GO:0040008,GO:0040009,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0046914,GO:0050789,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158416_k127_2985754_18	1032480.MLP_46510	7.005e-46	172.0	COG0494@1|root,COG0494@2|Bacteria,2HZ8R@201174|Actinobacteria,4DR5X@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158416_k127_2985754_28	1128421.JAGA01000003_gene2971	5.749e-05	55.0	2EG64@1|root,339XZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_2985754_22	1122611.KB903939_gene443	6.052e-29	125.0	COG0454@1|root,COG0456@2|Bacteria,2I9GA@201174|Actinobacteria,4EIQH@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_3021089_0	211114.JOEF01000039_gene6343	1.871e-103	346.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4DX7R@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Alpha amylase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SRR25158416_k127_3021089_1	391624.OIHEL45_17496	0.0004131	46.0	COG0251@1|root,COG0251@2|Bacteria,1RDFC@1224|Proteobacteria,2U8PR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158416_k127_3030121_0	1380370.JIBA01000017_gene2937	2.631e-91	310.0	2FD8H@1|root,345AH@2|Bacteria,2GS0J@201174|Actinobacteria,4FIXE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3030121_1	1380370.JIBA01000017_gene2938	3.498e-87	291.0	COG1131@1|root,COG1131@2|Bacteria,2H3JQ@201174|Actinobacteria,4FINS@85021|Intrasporangiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158416_k127_3030654_6	953739.SVEN_5266	3.322e-16	83.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_3030654_0	1120950.KB892741_gene2713	5.273e-98	329.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4DN7J@85009|Propionibacteriales	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158416_k127_3030654_5	1312959.KI914652_gene463	7.125e-20	91.0	COG0333@1|root,COG0333@2|Bacteria,2HT7Q@201174|Actinobacteria,1W9PQ@1268|Micrococcaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158416_k127_3030654_2	711393.AYRX01000095_gene3659	1.303e-64	227.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria	201174|Actinobacteria	S	metal-binding, possibly nucleic acid-binding protein	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158416_k127_3030654_4	100226.SCO5569	5.152e-29	123.0	COG0711@1|root,COG0711@2|Bacteria,2GNBF@201174|Actinobacteria	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3030654_1	1114959.SZMC14600_11073	2.472e-65	226.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4E33S@85010|Pseudonocardiales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158416_k127_3030654_3	58123.JOFJ01000003_gene2061	2.26e-36	141.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4EJ83@85012|Streptosporangiales	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158416_k127_3039051_0	935866.JAER01000022_gene2954	1.197e-11	68.0	2B164@1|root,31TK6@2|Bacteria,2HUZT@201174|Actinobacteria,4DW0I@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3047912_0	1123024.AUII01000021_gene34	1.709e-78	286.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4DY0W@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158416_k127_3067162_24	426355.Mrad2831_5489	3.307e-08	55.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria,1JZ9C@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158416_k127_3067162_20	1160718.SU9_33248	9.784e-58	218.0	COG1335@1|root,COG1335@2|Bacteria,2IG6Q@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158416_k127_3067162_23	1122611.KB903952_gene5930	1.343e-10	71.0	COG1335@1|root,COG1335@2|Bacteria,2IG6Q@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158416_k127_3067162_21	1382356.JQMP01000003_gene1667	8.941e-39	159.0	COG2141@1|root,COG2141@2|Bacteria,2GB9A@200795|Chloroflexi,27Y8J@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3067162_16	1120949.KB903315_gene252	3.71e-100	338.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria,4DII5@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158416_k127_3067162_6	526225.Gobs_2398	6.033e-176	562.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EVDD@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_3067162_19	345341.KUTG_00776	1.67e-61	224.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,4E1G7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158416_k127_3067162_14	1074488.AGBX01000001_gene976	1.975e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,2GWHQ@201174|Actinobacteria,4FCM8@85020|Dermabacteraceae	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3067162_15	1298880.AUEV01000018_gene248	2.261e-101	337.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158416_k127_3067162_0	479435.Kfla_6813	3.39e-318	988.0	COG0247@1|root,COG1150@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,2GJ7M@201174|Actinobacteria,4DNU0@85009|Propionibacteriales	201174|Actinobacteria	C	Cysteine-rich domain	fadF	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158416_k127_3067162_4	1380347.JNII01000005_gene3244	3.836e-236	743.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4ES63@85013|Frankiales	201174|Actinobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158416_k127_3067162_1	566461.SSFG_04302	2.282e-313	971.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158416_k127_3067162_10	446470.Snas_3339	8.218e-166	534.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_3067162_11	1380347.JNII01000005_gene3246	1.902e-155	505.0	COG0624@1|root,COG0624@2|Bacteria,2GJDE@201174|Actinobacteria,4ERZX@85013|Frankiales	201174|Actinobacteria	E	Peptidase family M20/M25/M40	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158416_k127_3067162_8	211114.JOEF01000001_gene7328	9.649e-174	560.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4DXKJ@85010|Pseudonocardiales	201174|Actinobacteria	F	Formiminoglutamate deiminase	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158416_k127_3067162_5	1150864.MILUP08_41447	2.473e-207	669.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DAZW@85008|Micromonosporales	201174|Actinobacteria	S	of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158416_k127_3067162_7	479435.Kfla_6770	1.418e-175	560.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4DN2W@85009|Propionibacteriales	201174|Actinobacteria	Q	imidazolonepropionase activity	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158416_k127_3067162_13	338963.Pcar_2461	2.691e-120	392.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43UKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158416_k127_3067162_17	2074.JNYD01000015_gene4498	2.96e-75	270.0	COG3503@1|root,COG3503@2|Bacteria,2I2JM@201174|Actinobacteria,4E008@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
SRR25158416_k127_3067162_2	1048339.KB913029_gene1469	2.48e-297	922.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4ERTY@85013|Frankiales	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158416_k127_3067162_18	1120950.KB892716_gene2444	2.276e-65	229.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4DQY5@85009|Propionibacteriales	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158416_k127_3067162_9	1223523.H340_15446	2.077e-168	537.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158416_k127_3067162_22	1211815.CBYP010000050_gene626	7.61e-35	139.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4ET08@85013|Frankiales	201174|Actinobacteria	K	transcriptional regulator, MerR	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158416_k127_3067162_12	234621.RER_57260	1.38e-144	471.0	COG0277@1|root,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4FYKW@85025|Nocardiaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158416_k127_3067162_3	1120950.KB892716_gene2447	9.001e-264	822.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4DN44@85009|Propionibacteriales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158416_k127_3071099_2	1123320.KB889676_gene2915	8.059e-181	572.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158416_k127_3071099_3	266940.Krad_1352	1.122e-172	548.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158416_k127_3071099_1	1120950.KB892741_gene2679	1.541e-182	576.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4DPRZ@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158416_k127_3071099_0	1120950.KB892741_gene2682	1.467e-265	826.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4DNDJ@85009|Propionibacteriales	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158416_k127_3076061_34	1089544.KB912942_gene1665	4.006e-07	56.0	COG5401@1|root,COG5401@2|Bacteria	2|Bacteria	T	PFAM Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	AMIN,Germane
SRR25158416_k127_3076061_36	666686.B1NLA3E_09955	4.944e-06	56.0	2AYD6@1|root,31QG1@2|Bacteria,1UBWV@1239|Firmicutes,4INCK@91061|Bacilli,1ZN9A@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3076061_33	1211815.CBYP010000013_gene3522	2.018e-07	53.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_3076061_0	1120950.KB892707_gene4745	2.202e-278	861.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4DNAS@85009|Propionibacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158416_k127_3076061_21	1120950.KB892707_gene4748	1.894e-64	233.0	2AUFS@1|root,31K3Y@2|Bacteria,2GIXC@201174|Actinobacteria,4DQHR@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4191)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4191
SRR25158416_k127_3076061_2	1121924.ATWH01000002_gene3774	6.159e-249	779.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria,4FQMK@85023|Microbacteriaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158416_k127_3076061_32	867903.ThesuDRAFT_01341	2.1e-10	64.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR25158416_k127_3076061_23	1120949.KB903357_gene4933	2.455e-55	213.0	COG4447@1|root,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3076061_35	266940.Krad_4338	5.972e-07	53.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria	201174|Actinobacteria	L	single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158416_k127_3076061_7	935866.JAER01000011_gene2235	1.13e-163	518.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4DPBB@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158416_k127_3076061_15	1136417.AZWE01000002_gene3506	4.607e-94	313.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4DADI@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158416_k127_3076061_25	1120950.KB892707_gene4754	4.703e-51	201.0	COG0515@1|root,COG0515@2|Bacteria,2ID99@201174|Actinobacteria,4DVH3@85009|Propionibacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158416_k127_3076061_17	66429.JOFL01000002_gene4182	2.026e-88	303.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria	201174|Actinobacteria	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158416_k127_3076061_4	1380356.JNIK01000021_gene4508	1.038e-205	657.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4ERCG@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E2 component	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158416_k127_3076061_3	196162.Noca_2304	6.511e-223	704.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4DN01@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_3076061_28	526225.Gobs_3359	3.137e-30	126.0	2E6TR@1|root,331DK@2|Bacteria,2IQF8@201174|Actinobacteria,4ET8F@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3076061_16	570268.ANBB01000007_gene5469	1.993e-89	307.0	COG1834@1|root,COG1834@2|Bacteria,2GNTN@201174|Actinobacteria,4EK6I@85012|Streptosporangiales	201174|Actinobacteria	E	Amidinotransferase	ddaH	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
SRR25158416_k127_3076061_8	1223523.H340_31493	1.357e-159	518.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158416_k127_3076061_9	1120950.KB892707_gene4760	1.938e-158	506.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DN5V@85009|Propionibacteriales	201174|Actinobacteria	E	Glycine cleavage system T protein	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158416_k127_3076061_24	326424.FRAAL5141	3.661e-54	203.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4ERJF@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2207	CobU,DBI_PRT
SRR25158416_k127_3076061_31	1116232.AHBF01000158_gene4131	5.249e-18	85.0	2EFWK@1|root,339NW@2|Bacteria,2IQXQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3076061_26	1133849.O3I_032120	1.518e-41	165.0	COG0454@1|root,COG0456@2|Bacteria,2IFF2@201174|Actinobacteria,4G1D6@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_3076061_27	1120950.KB892707_gene4775	1.836e-41	166.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4DRVQ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
SRR25158416_k127_3076061_14	1157640.AQWO01000009_gene508	7.114e-104	344.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158416_k127_3076061_30	105425.BBPL01000031_gene4467	8.977e-26	111.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria,2NJDW@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3076061_13	1120950.KB892707_gene4778	2.073e-104	347.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4DN0F@85009|Propionibacteriales	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158416_k127_3076061_20	1223523.H340_23258	1.792e-67	242.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3076061_5	1122611.KB903947_gene933	1.762e-198	636.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4EHP0@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158416_k127_3076061_18	1120950.KB892707_gene4780	7.599e-71	255.0	COG0454@1|root,COG0454@2|Bacteria,2H2PG@201174|Actinobacteria,4DNDQ@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158416_k127_3076061_11	1120950.KB892707_gene4781	1.302e-140	459.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4DMYU@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158416_k127_3076061_22	1157637.KB892090_gene6419	2.831e-60	210.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158416_k127_3076061_10	67373.JOBF01000015_gene5130	1.654e-141	458.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria	201174|Actinobacteria	G	Ribokinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158416_k127_3076061_19	55952.BU52_10185	2.435e-68	238.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158416_k127_3076061_1	37919.EP51_17260	2.824e-260	812.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4FXZ9@85025|Nocardiaceae	201174|Actinobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3076061_29	1380356.JNIK01000015_gene2346	3.805e-29	126.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria	201174|Actinobacteria	E	arginine	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158416_k127_3076061_6	1380356.JNIK01000015_gene2347	5.007e-173	547.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4ERRI@85013|Frankiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158416_k127_3076061_12	1380356.JNIK01000015_gene2348	1.811e-136	443.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the carbamate kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158416_k127_3082469_6	710696.Intca_2641	1.273e-14	76.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2HREU@201174|Actinobacteria,4FFZI@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
SRR25158416_k127_3082469_0	1313172.YM304_32120	1.497e-121	409.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CNFR@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3082469_2	66373.JOFQ01000001_gene1898	1.46e-63	229.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158416_k127_3082469_1	713587.THITH_11145	6.154e-80	278.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1S2FY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_3082469_4	1077974.GOEFS_086_00500	6.229e-31	126.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4GCP8@85026|Gordoniaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3082469_5	2002.JOEQ01000026_gene370	6.669e-19	91.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EHHD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3082469_3	1283283.ATXA01000003_gene1597	8.5e-59	208.0	COG0526@1|root,COG0526@2|Bacteria,2GKDT@201174|Actinobacteria,4EUSR@85013|Frankiales	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	dipZ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRR25158416_k127_3085218_0	1394178.AWOO02000003_gene2762	6.511e-319	979.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EFUP@85012|Streptosporangiales	201174|Actinobacteria	L	ABC transporter	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158416_k127_3085218_7	479432.Sros_5396	1.199e-79	272.0	COG1670@1|root,COG1670@2|Bacteria,2IHXG@201174|Actinobacteria,4EN7J@85012|Streptosporangiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158416_k127_3085218_6	479432.Sros_5450	8.553e-109	361.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria,4EFU1@85012|Streptosporangiales	201174|Actinobacteria	J	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158416_k127_3085218_17	1179773.BN6_57740	5.722e-19	94.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria,4E7U5@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
SRR25158416_k127_3085218_9	570268.ANBB01000064_gene1018	6.281e-71	254.0	COG0454@1|root,COG0456@2|Bacteria,2GY1D@201174|Actinobacteria,4EKQH@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_3085218_18	1120949.KB903306_gene7572	1.702e-12	79.0	COG1361@1|root,COG2304@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,2I8F1@201174|Actinobacteria,4DFBB@85008|Micromonosporales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3344
SRR25158416_k127_3085218_4	1463825.JNXC01000043_gene7454	4.359e-115	394.0	COG2304@1|root,COG2304@2|Bacteria,2GUB3@201174|Actinobacteria,4E1CP@85010|Pseudonocardiales	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,VWA
SRR25158416_k127_3085218_13	1123320.KB889618_gene7128	1.205e-58	213.0	COG0726@1|root,COG0726@2|Bacteria,2GN6G@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K14659,ko:K22278	-	M00664	-	-	ko00000,ko00002,ko01000	-	-	-	Polysacc_deac_1
SRR25158416_k127_3085218_14	1068978.AMETH_4350	9.327e-56	205.0	COG0726@1|root,COG0726@2|Bacteria,2GN6G@201174|Actinobacteria,4E4NT@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K14659,ko:K22278	-	M00664	-	-	ko00000,ko00002,ko01000	-	-	-	Polysacc_deac_1
SRR25158416_k127_3085218_15	44060.JODL01000004_gene2457	6.708e-47	174.0	COG5083@1|root,COG5083@2|Bacteria,2IFC7@201174|Actinobacteria	201174|Actinobacteria	S	phosphatidylinositol transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRR25158416_k127_3085218_11	1906.SFRA_11635	2.036e-65	233.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_3085218_16	1463825.JNXC01000071_gene3282	3.537e-40	159.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4E4IM@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158416_k127_3085218_5	593907.Celgi_2988	1.975e-112	374.0	COG0644@1|root,COG0644@2|Bacteria,2GM2M@201174|Actinobacteria,4F10K@85016|Cellulomonadaceae	201174|Actinobacteria	C	FAD binding domain	srsC	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
SRR25158416_k127_3085218_10	935839.JAGJ01000003_gene1579	1.839e-69	240.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria,4F4FE@85017|Promicromonosporaceae	201174|Actinobacteria	S	Phospholipid methyltransferase	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
SRR25158416_k127_3085218_3	67281.JNZZ01000019_gene122	1.046e-133	434.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,417B1@629295|Streptomyces griseus group	201174|Actinobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	pks11	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRR25158416_k127_3085218_1	1120950.KB892708_gene4185	4.625e-243	761.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4DP14@85009|Propionibacteriales	201174|Actinobacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158416_k127_3085218_2	1120950.KB892708_gene4184	2.858e-192	617.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,4DQ2P@85009|Propionibacteriales	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158416_k127_3085218_8	1120950.KB892821_gene693	5.408e-77	258.0	COG0346@1|root,COG0346@2|Bacteria,2IHU2@201174|Actinobacteria,4DUZE@85009|Propionibacteriales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3085218_12	284031.JNXD01000009_gene2167	3.963e-61	211.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158416_k127_3087661_12	1121272.KB903249_gene1606	6.146e-18	85.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria,4DBIP@85008|Micromonosporales	201174|Actinobacteria	KT	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,LMWPc
SRR25158416_k127_3087661_9	1123024.AUII01000033_gene1400	2.09e-38	145.0	2FCGD@1|root,344JU@2|Bacteria,2IRV1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3087661_0	1237500.ANBA01000021_gene5311	6.156e-150	482.0	COG2197@1|root,COG2197@2|Bacteria,2IBK0@201174|Actinobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_3087661_2	405948.SACE_3408	7.646e-101	337.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4E3CN@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
SRR25158416_k127_3087661_10	1122138.AQUZ01000049_gene2373	1.717e-35	138.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4DRJS@85009|Propionibacteriales	201174|Actinobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158416_k127_3087661_3	1449044.JMLE01000003_gene2828	8.475e-77	262.0	COG2346@1|root,COG2346@2|Bacteria,2GMG5@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158416_k127_3087661_7	1459636.NTE_00013	1.659e-53	198.0	COG2085@1|root,arCOG00457@2157|Archaea	2157|Archaea	S	NADPH-dependent F420 reductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored,HTH_10
SRR25158416_k127_3087661_1	1122138.AQUZ01000086_gene1202	5.083e-111	370.0	COG0667@1|root,COG0667@2|Bacteria,2ICZ6@201174|Actinobacteria,4DU0W@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_3087661_4	1394178.AWOO02000054_gene8006	2.035e-70	251.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4EPD8@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3087661_5	379066.GAU_1162	1.36e-66	244.0	COG0654@1|root,COG0654@2|Bacteria,1ZV54@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158416_k127_3087661_11	1122611.KB903979_gene3286	2.736e-33	139.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4EIR7@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158416_k127_3087661_6	1120950.KB892769_gene5385	4.171e-56	204.0	COG4894@1|root,COG4894@2|Bacteria,2IH17@201174|Actinobacteria,4DQZ8@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3087661_8	1380390.JIAT01000010_gene4196	3.072e-39	148.0	COG2197@1|root,COG2197@2|Bacteria,2HQF1@201174|Actinobacteria,4CRZT@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3102873_1	1123023.JIAI01000010_gene8515	5.577e-22	94.0	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria,4DXM5@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_3102873_0	1229780.BN381_130338	2.508e-41	166.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158416_k127_3102873_2	1120936.KB907217_gene3516	1.01e-13	70.0	COG1960@1|root,COG1960@2|Bacteria,2HY6H@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE21	-	-	ko:K00257	-	-	R04547,R04592	RC01942	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_310900_12	649831.L083_7000	0.000945	43.0	COG0620@1|root,COG0620@2|Bacteria,2GMPS@201174|Actinobacteria,4D9B2@85008|Micromonosporales	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
SRR25158416_k127_310900_4	1120950.KB892741_gene2650	6.814e-170	556.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4DPXG@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158416_k127_310900_5	1120950.KB892741_gene2649	5.88e-164	528.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4DNQT@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-V	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158416_k127_310900_7	1120950.KB892741_gene2646	1.093e-133	436.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DNKA@85009|Propionibacteriales	201174|Actinobacteria	C	electron transfer flavoprotein, alpha subunit	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158416_k127_310900_10	1386089.N865_06610	8.737e-109	357.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4FEFQ@85021|Intrasporangiaceae	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158416_k127_310900_9	105425.BBPL01000004_gene7640	9.912e-116	379.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,2NHCD@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158416_k127_310900_8	196162.Noca_0658	1.564e-126	411.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4DPHZ@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_310900_2	526225.Gobs_4097	1.552e-281	880.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4ERI9@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX2	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158416_k127_310900_0	1120950.KB892798_gene2197	0.0	1204.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4DPQE@85009|Propionibacteriales	201174|Actinobacteria	G	Protein of unknown function (DUF3417)	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158416_k127_310900_3	1157637.KB892146_gene7086	5.812e-275	859.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158416_k127_310900_1	1120950.KB892798_gene2195	0.0	1010.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DNMJ@85009|Propionibacteriales	201174|Actinobacteria	G	Trehalose synthase	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
SRR25158416_k127_310900_6	1120950.KB892798_gene2194	2.486e-135	445.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4DNWM@85009|Propionibacteriales	201174|Actinobacteria	G	protein probably involved in trehalose biosynthesis	mak	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158416_k127_310900_11	1386089.N865_20595	4.884e-15	78.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4FJ1I@85021|Intrasporangiaceae	201174|Actinobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_3115419_0	479434.Sthe_1268	7.6e-11	69.0	COG4454@1|root,COG4454@2|Bacteria,2GBEQ@200795|Chloroflexi,27Z6N@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3125951_5	367299.JOEE01000003_gene2933	4.093e-20	97.0	COG1652@1|root,COG1652@2|Bacteria,2GQMU@201174|Actinobacteria,4FH7Q@85021|Intrasporangiaceae	201174|Actinobacteria	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158416_k127_3125951_6	1120950.KB892764_gene5603	4.075e-19	95.0	2DPN9@1|root,332RH@2|Bacteria,2GVN7@201174|Actinobacteria,4DSF3@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3125951_0	1120950.KB892764_gene5602	0.0	1285.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4DPEU@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158416_k127_3125951_2	1120950.KB892764_gene5601	4.092e-106	360.0	COG1670@1|root,COG1670@2|Bacteria,2GMDB@201174|Actinobacteria,4DQEE@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158416_k127_3125951_1	1120950.KB892764_gene5600	4.036e-165	528.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4DN5U@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158416_k127_3125951_3	67257.JODR01000017_gene4536	1.647e-65	232.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158416_k127_3125951_4	105420.BBPO01000069_gene4129	2.036e-38	153.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,2NI8Y@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphoribosyl transferase domain	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158416_k127_3125951_7	1120950.KB892764_gene5596	2.549e-11	68.0	COG5401@1|root,COG5401@2|Bacteria,2GJ5Y@201174|Actinobacteria,4DQ1Z@85009|Propionibacteriales	201174|Actinobacteria	M	Sporulation and spore germination	lpqB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Germane,Gmad1
SRR25158416_k127_3138241_3	287986.DV20_02515	1.363e-39	156.0	COG1116@1|root,COG1116@2|Bacteria,2IBEK@201174|Actinobacteria,4EEKT@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158416_k127_3138241_2	1246995.AFR_34580	3.822e-99	346.0	COG0600@1|root,COG0600@2|Bacteria,2ICUJ@201174|Actinobacteria,4DHTG@85008|Micromonosporales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158416_k127_3138241_1	298655.KI912266_gene3763	9.338e-138	450.0	COG0715@1|root,COG0715@2|Bacteria,2HFUC@201174|Actinobacteria,4EX10@85013|Frankiales	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158416_k127_3138241_0	345341.KUTG_03740	7.203e-205	645.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4E9T2@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158416_k127_3138824_2	1121926.AXWO01000013_gene2175	9.075e-46	173.0	COG3408@1|root,COG3408@2|Bacteria,2H8PD@201174|Actinobacteria	201174|Actinobacteria	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C
SRR25158416_k127_3138824_0	1532557.JL37_12335	1.008e-128	419.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2W1SZ@28216|Betaproteobacteria,3T6IE@506|Alcaligenaceae	28216|Betaproteobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	yhdN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_3138824_1	1101188.KI912155_gene3631	5.05e-96	333.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3140206_11	443255.SCLAV_1363	4.552e-132	428.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158416_k127_3140206_26	67352.JODS01000031_gene797	4.969e-52	188.0	COG4803@1|root,COG4803@2|Bacteria,2IHYU@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158416_k127_3140206_29	1120950.KB892707_gene4806	4.454e-39	151.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4DRN1@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158416_k127_3140206_23	47716.JOFH01000027_gene3082	6.559e-81	287.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158416_k127_3140206_0	1120950.KB892707_gene4807	5.569e-229	723.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,2GMC0@201174|Actinobacteria,4DNVQ@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III, epsilon subunit	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158416_k127_3140206_33	1894.JOER01000001_gene5298	2.211e-27	113.0	2ES7R@1|root,33JSG@2|Bacteria,2IQ6C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3140206_19	1210045.ALNP01000009_gene4833	1.504e-107	365.0	COG3688@1|root,COG3688@2|Bacteria,2GR19@201174|Actinobacteria	201174|Actinobacteria	M	RNA-binding protein containing a PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158416_k127_3140206_38	1068980.ARVW01000001_gene5522	9.077e-17	83.0	2EGHN@1|root,33A9R@2|Bacteria,2GSZ1@201174|Actinobacteria,4E7HS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3140206_24	1120950.KB892707_gene4812	1.104e-74	266.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4DQU1@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158416_k127_3140206_31	1156844.KB891820_gene129	8.152e-31	136.0	COG0308@1|root,COG0308@2|Bacteria,2GK29@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3140206_13	1123320.KB889675_gene3911	1.993e-126	418.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria	201174|Actinobacteria	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158416_k127_3140206_6	1120950.KB892707_gene4815	6.88e-156	519.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DQ0Q@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_3140206_28	1894.JOER01000001_gene5307	1.404e-48	181.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria	201174|Actinobacteria	I	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158416_k127_3140206_15	1464048.JNZS01000034_gene2635	1.075e-113	374.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4D97U@85008|Micromonosporales	201174|Actinobacteria	GK	ROK family	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158416_k127_3140206_16	47763.JNZA01000006_gene976	1.03e-110	367.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158416_k127_3140206_27	351607.Acel_0980	1.252e-51	191.0	COG3568@1|root,COG3568@2|Bacteria,2GMRU@201174|Actinobacteria	201174|Actinobacteria	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158416_k127_3140206_35	269800.Tfu_1035	3.46e-25	110.0	2EN8E@1|root,33FW7@2|Bacteria,2GMI1@201174|Actinobacteria,4EJV7@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3140206_22	1120950.KB892707_gene4849	7.701e-95	318.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,4DNFV@85009|Propionibacteriales	201174|Actinobacteria	S	Serine aminopeptidase, S33	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158416_k127_3140206_18	313589.JNB_01560	1.202e-108	355.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FEIG@85021|Intrasporangiaceae	201174|Actinobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_3140206_2	1385518.N798_13080	1.287e-202	636.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4FG41@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.90	ko:K00895	ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130	-	R00764,R02073	RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158416_k127_3140206_1	469371.Tbis_1899	3.455e-217	681.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4DZSR@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158416_k127_3140206_12	1120950.KB892707_gene4856	7.834e-132	429.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4DPQR@85009|Propionibacteriales	201174|Actinobacteria	E	Beta-eliminating lyase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158416_k127_3140206_10	479432.Sros_5210	2.421e-134	439.0	COG0730@1|root,COG0730@2|Bacteria,2GNPE@201174|Actinobacteria,4EI0K@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	cysZ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158416_k127_3140206_5	479432.Sros_2759	1.488e-159	510.0	COG2876@1|root,COG2876@2|Bacteria,2I3UA@201174|Actinobacteria,4EI1I@85012|Streptosporangiales	201174|Actinobacteria	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158416_k127_3140206_8	479435.Kfla_2845	1.319e-146	488.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DPC3@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158416_k127_3140206_14	1869.MB27_20555	2.548e-123	406.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4D8QG@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158416_k127_3140206_9	365528.KB891102_gene4445	4.462e-139	448.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4ERKZ@85013|Frankiales	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158416_k127_3140206_30	1146883.BLASA_0814	5.867e-37	149.0	COG2968@1|root,COG2968@2|Bacteria,2GM1U@201174|Actinobacteria,4ET95@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF541)	lpqG	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158416_k127_3140206_41	1207063.P24_09151	3.109e-06	56.0	COG1233@1|root,COG1233@2|Bacteria,1MX1C@1224|Proteobacteria,2TS2R@28211|Alphaproteobacteria,2JQ34@204441|Rhodospirillales	204441|Rhodospirillales	Q	Flavin containing amine oxidoreductase	crtD	-	1.3.99.27	ko:K09845	ko00906,ko01100,map00906,map01100	-	R07517,R07520,R07523,R07534	RC02080	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158416_k127_3140206_37	1380356.JNIK01000013_gene4257	8.975e-23	104.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4ETTQ@85013|Frankiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI2	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158416_k127_3140206_25	1120950.KB892707_gene4872	1.351e-52	191.0	28JRZ@1|root,2Z9HI@2|Bacteria,2H9EF@201174|Actinobacteria,4DQX2@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRR25158416_k127_3140206_32	1380347.JNII01000008_gene4227	7.31e-29	122.0	2CGM3@1|root,32S47@2|Bacteria,2GP7H@201174|Actinobacteria,4ET5Q@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3140206_21	263358.VAB18032_14115	5.672e-100	343.0	COG1938@1|root,COG1938@2|Bacteria,2I2N7@201174|Actinobacteria,4DBJV@85008|Micromonosporales	201174|Actinobacteria	S	PAC2 family	pac	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158416_k127_3140206_39	1150599.MPHLEI_19300	8.91e-15	84.0	2E65S@1|root,330UF@2|Bacteria,2IMEQ@201174|Actinobacteria,23A2H@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3817
SRR25158416_k127_3140206_36	28444.JODQ01000005_gene1287	1.939e-23	109.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,4EHHN@85012|Streptosporangiales	201174|Actinobacteria	S	SURF1 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
SRR25158416_k127_3140206_34	33876.JNXY01000006_gene968	1.222e-26	113.0	COG3339@1|root,COG3339@2|Bacteria,2GQGT@201174|Actinobacteria,4DEFZ@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158416_k127_3140206_3	1048339.KB913029_gene4959	1.668e-194	619.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4ERUG@85013|Frankiales	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158416_k127_3140206_20	1120950.KB892768_gene5344	2.721e-103	350.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DNEM@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158416_k127_3140206_7	1120950.KB892768_gene5343	5.147e-151	494.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4DP7S@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	mprB	GO:0000160,GO:0003674,GO:0003824,GO:0004721,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0040007,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158416_k127_3140206_17	345341.KUTG_04494	6.453e-110	360.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DXHB@85010|Pseudonocardiales	201174|Actinobacteria	T	response regulator	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3140206_4	1120950.KB892768_gene5336	2.896e-162	521.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DN0X@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158416_k127_3156782_3	1121272.KB903290_gene4487	7.224e-28	119.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3156782_5	1463861.JNXE01000003_gene4105	9.855e-20	91.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria	201174|Actinobacteria	CH	monooxygenase, FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158416_k127_3156782_2	456442.Mboo_2313	9.977e-47	184.0	COG5485@1|root,arCOG06513@2157|Archaea,2Y3E5@28890|Euryarchaeota	28890|Euryarchaeota	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158416_k127_3156782_11	1312954.KI914848_gene2058	1.756e-10	73.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3156782_10	570952.ATVH01000011_gene640	1.736e-11	75.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2TUKD@28211|Alphaproteobacteria,2JRK5@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_3156782_4	1283283.ATXA01000001_gene642	5.522e-20	96.0	COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4EWMZ@85013|Frankiales	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR25158416_k127_3156782_7	1968.JOEV01000056_gene4922	1.025e-14	81.0	COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR25158416_k127_3156782_14	1343740.M271_23335	0.0001799	49.0	2B50U@1|root,31XTZ@2|Bacteria,2GZNJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3156782_0	760568.Desku_1403	2.01e-115	386.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia,265ZW@186807|Peptococcaceae	186801|Clostridia	S	Phage plasmid primase, P4	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
SRR25158416_k127_3156782_6	196162.Noca_0561	6.106e-17	84.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR_1
SRR25158416_k127_3156782_9	557599.MKAN_11360	1.473e-13	78.0	292M5@1|root,2ZQ52@2|Bacteria,2HSYF@201174|Actinobacteria,23EJE@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3156782_1	526225.Gobs_0014	6.411e-103	346.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int8	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_3156782_13	253839.SSNG_00114	3.583e-06	49.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_316575_0	1416759.AYMR01000011_gene380	2.99e-254	795.0	COG3250@1|root,COG3250@2|Bacteria,2I8XI@201174|Actinobacteria,4FPD3@85023|Microbacteriaceae	201174|Actinobacteria	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
SRR25158416_k127_316575_1	1032480.MLP_52070	2.684e-124	407.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_3167888_2	1089545.KB913037_gene1700	1.93e-20	93.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158416_k127_3167888_4	512565.AMIS_65410	2.699e-05	54.0	COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,4DCEH@85008|Micromonosporales	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158416_k127_3167888_5	1122182.KB903837_gene3895	3.329e-05	51.0	COG3861@1|root,COG3861@2|Bacteria,2IQ4Y@201174|Actinobacteria,4DF3X@85008|Micromonosporales	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3167888_3	263358.VAB18032_11240	2.863e-08	58.0	COG3861@1|root,COG3861@2|Bacteria,2IQ4Y@201174|Actinobacteria,4DEHC@85008|Micromonosporales	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3167888_0	930171.Asphe3_00480	3.17e-50	193.0	COG1503@1|root,COG1503@2|Bacteria,2GNN3@201174|Actinobacteria,1WAZ0@1268|Micrococcaceae	201174|Actinobacteria	J	translation release factor activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
SRR25158416_k127_3167888_1	710421.Mycch_0782	1.865e-49	183.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,23549@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3180558_0	743718.Isova_1671	4.856e-186	589.0	COG2866@1|root,COG2866@2|Bacteria,2I1HU@201174|Actinobacteria	201174|Actinobacteria	E	carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_3180558_1	1209984.BN978_06070	8.845e-136	441.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
SRR25158416_k127_3190461_2	1120950.KB892779_gene945	3.018e-162	517.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DQ3H@85009|Propionibacteriales	201174|Actinobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158416_k127_3190461_0	67352.JODS01000007_gene4611	5.4e-323	996.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158416_k127_3190461_5	591157.SSLG_04020	9.745e-97	331.0	COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158416_k127_3190461_7	1463934.JOCF01000001_gene6951	3.914e-68	236.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158416_k127_3190461_4	1120950.KB892779_gene936	2.208e-152	495.0	COG1005@1|root,COG1005@2|Bacteria,2GN3R@201174|Actinobacteria,4DU89@85009|Propionibacteriales	201174|Actinobacteria	C	NADH dehydrogenase	nuoH2	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158416_k127_3190461_6	1463856.JOHY01000030_gene2876	3.628e-85	286.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158416_k127_3190461_8	1120950.KB892779_gene934	5.243e-46	172.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria,4DV5E@85009|Propionibacteriales	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158416_k127_3190461_9	1449347.JQLN01000005_gene5323	1.937e-38	149.0	COG0713@1|root,COG0713@2|Bacteria,2IHNW@201174|Actinobacteria,2M386@2063|Kitasatospora	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158416_k127_3190461_1	1120950.KB892779_gene932	3.354e-166	543.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4DT5U@85009|Propionibacteriales	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158416_k127_3190461_3	1449347.JQLN01000005_gene5325	5.431e-157	538.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,2M1QG@2063|Kitasatospora	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158416_k127_3190461_10	1463936.JOJI01000014_gene6880	2.975e-13	75.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158416_k127_3214595_2	1116232.AHBF01000033_gene4837	2.879e-173	553.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria	201174|Actinobacteria	P	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_3214595_4	285535.JOEY01000042_gene1110	1.951e-45	173.0	COG2190@1|root,COG2190@2|Bacteria,2GK6B@201174|Actinobacteria	201174|Actinobacteria	G	Pts system	ptbA	-	2.7.1.193	ko:K02777,ko:K02802	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00267,M00268,M00270,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R05199,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.1.2	-	-	PTS_EIIA_1
SRR25158416_k127_3214595_5	1463825.JNXC01000018_gene6794	5.874e-29	117.0	COG1264@1|root,COG1264@2|Bacteria,2IQIB@201174|Actinobacteria,4E5CJ@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphotransferase System	-	-	2.7.1.193	ko:K02803	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB
SRR25158416_k127_3214595_0	1304865.JAGF01000001_gene3918	2.138e-185	591.0	COG1263@1|root,COG1263@2|Bacteria,2GKPM@201174|Actinobacteria	201174|Actinobacteria	G	Phosphotransferase System	gamP	-	-	ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIC
SRR25158416_k127_3214595_1	446466.Cfla_1360	3.926e-180	580.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4F207@85016|Cellulomonadaceae	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158416_k127_3214595_3	68570.DC74_7465	1.171e-94	324.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158416_k127_3214595_6	1179773.BN6_63380	1.154e-26	112.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4E63H@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Phosphotransferase System HPr (HPr) Family	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRR25158416_k127_3223740_24	1380356.JNIK01000001_gene2149	2.646e-16	80.0	COG2261@1|root,COG2261@2|Bacteria,2IQGM@201174|Actinobacteria,4ETK1@85013|Frankiales	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158416_k127_3223740_14	1120950.KB892823_gene459	4.17e-103	342.0	COG3396@1|root,COG3396@2|Bacteria,2GKXZ@201174|Actinobacteria,4DMYE@85009|Propionibacteriales	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
SRR25158416_k127_3223740_5	1120950.KB892823_gene460	1.134e-197	628.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNNT@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158416_k127_3223740_23	1120950.KB892823_gene461	4.824e-18	86.0	COG1376@1|root,COG1376@2|Bacteria,2IIU7@201174|Actinobacteria,4DRAD@85009|Propionibacteriales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158416_k127_3223740_18	1122138.AQUZ01000016_gene229	8.411e-77	273.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
SRR25158416_k127_3223740_27	1265310.CCBD010000019_gene4064	3.609e-07	56.0	2B360@1|root,31VTY@2|Bacteria,2H0U9@201174|Actinobacteria,23BEJ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3223740_25	408672.NBCG_05638	1.41e-12	72.0	COG1376@1|root,COG1376@2|Bacteria,2IIU7@201174|Actinobacteria,4DRAD@85009|Propionibacteriales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158416_k127_3223740_16	1120950.KB892823_gene462	6.966e-84	287.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria,4DQN5@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_3223740_11	356851.JOAN01000022_gene2201	5.058e-110	368.0	COG1132@1|root,COG1132@2|Bacteria,2GJTA@201174|Actinobacteria,4DBSJ@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_3223740_22	465541.ATCJ01000005_gene3746	2.201e-23	116.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K03466,ko:K06147	-	-	-	-	ko00000,ko02000,ko03036	3.A.1.106,3.A.1.109,3.A.1.21,3.A.12	-	-	-
SRR25158416_k127_3223740_20	266940.Krad_1164	3.103e-70	250.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria	201174|Actinobacteria	U	UPF0056 membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158416_k127_3223740_15	408672.NBCG_05635	4.573e-95	320.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4DP8Q@85009|Propionibacteriales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158416_k127_3223740_21	1120950.KB892823_gene466	6.56e-64	225.0	29V8K@1|root,30GNI@2|Bacteria,2GM77@201174|Actinobacteria,4DR42@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3223740_10	1120950.KB892769_gene5417	9.107e-113	382.0	COG5002@1|root,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria,4DWYJ@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158416_k127_3223740_13	1122611.KB903944_gene1202	9.241e-109	359.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4EGJ6@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3223740_17	369723.Strop_1593	6.084e-81	283.0	COG2834@1|root,COG2834@2|Bacteria,2GKA2@201174|Actinobacteria,4D8U8@85008|Micromonosporales	201174|Actinobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092,MucB_RseB
SRR25158416_k127_3223740_12	1133850.SHJG_5727	3.774e-109	363.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_3223740_19	1120950.KB892769_gene5421	7.295e-75	261.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4DQVJ@85009|Propionibacteriales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158416_k127_3223740_4	1370121.AUWS01000033_gene4223	1.621e-209	659.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,235F1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	ddc	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158416_k127_3223740_6	35754.JNYJ01000050_gene7957	1.198e-151	487.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4DAEY@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158416_k127_3223740_2	479431.Namu_0813	9.309e-215	677.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,4EU7V@85013|Frankiales	201174|Actinobacteria	E	PFAM amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158416_k127_3223740_9	105420.BBPO01000112_gene7206	6.524e-119	401.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria,2NHT6@228398|Streptacidiphilus	201174|Actinobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRR25158416_k127_3223740_3	298653.Franean1_0897	1.552e-211	666.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4ERVR@85013|Frankiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158416_k127_3223740_8	1278309.KB907099_gene2604	5.969e-133	438.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,1RP33@1236|Gammaproteobacteria,1XJKY@135619|Oceanospirillales	135619|Oceanospirillales	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158416_k127_3223740_7	1370121.AUWS01000006_gene5229	5.155e-144	474.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,23431@1762|Mycobacteriaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_3223740_0	1370121.AUWS01000006_gene5227	1.9e-263	816.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,232XE@1762|Mycobacteriaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_3223740_1	1209984.BN978_05382	2.795e-256	801.0	COG0439@1|root,COG0439@2|Bacteria,2HTQR@201174|Actinobacteria,23508@1762|Mycobacteriaceae	201174|Actinobacteria	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2
SRR25158416_k127_3223740_26	1380356.JNIK01000014_gene3088	5.868e-08	58.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria,4EU0F@85013|Frankiales	201174|Actinobacteria	Q	amine oxidase	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRR25158416_k127_322403_2	680198.SCAB_88281	1.999e-40	151.0	COG2080@1|root,COG2080@2|Bacteria,2IFZ2@201174|Actinobacteria	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158416_k127_322403_1	408672.NBCG_03545	1.685e-50	189.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4DR04@85009|Propionibacteriales	201174|Actinobacteria	S	MobA-like NTP transferase domain	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158416_k127_322403_0	367299.JOEE01000001_gene2116	2.606e-152	493.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4FEEE@85021|Intrasporangiaceae	201174|Actinobacteria	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158416_k127_322403_3	590998.Celf_2283	1.264e-15	78.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4F0T5@85016|Cellulomonadaceae	201174|Actinobacteria	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158416_k127_3226919_1	1120950.KB892746_gene3508	2.928e-201	629.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DPAI@85009|Propionibacteriales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158416_k127_3226919_2	1304876.AZVC01000002_gene840	3.207e-184	593.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria,1WC27@1268|Micrococcaceae	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3226919_8	1032480.MLP_11810	1.115e-84	291.0	COG0598@1|root,COG0598@2|Bacteria,2IB0N@201174|Actinobacteria,4DUPR@85009|Propionibacteriales	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
SRR25158416_k127_3226919_0	1123024.AUII01000005_gene2420	3.754e-232	736.0	COG3243@1|root,COG3243@2|Bacteria,2GNYP@201174|Actinobacteria,4E13S@85010|Pseudonocardiales	201174|Actinobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phbC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
SRR25158416_k127_3226919_7	1120948.KB903243_gene2524	1.584e-103	342.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4E2QJ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3226919_6	1123023.JIAI01000021_gene2360	9.913e-126	412.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4DZM8@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_3226919_4	105422.BBPM01000001_gene4705	6.045e-163	521.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,2NEU0@228398|Streptacidiphilus	201174|Actinobacteria	E	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_3226919_3	105422.BBPM01000001_gene4704	3.749e-163	524.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158416_k127_3226919_9	526225.Gobs_2757	3.458e-53	189.0	COG1942@1|root,COG1942@2|Bacteria,2IMQ7@201174|Actinobacteria,4EVZI@85013|Frankiales	201174|Actinobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase_2
SRR25158416_k127_3226919_5	351607.Acel_1810	1.037e-141	455.0	COG1082@1|root,COG1082@2|Bacteria,2GMU1@201174|Actinobacteria,4EUHF@85013|Frankiales	201174|Actinobacteria	G	PFAM Xylose isomerase domain protein TIM barrel	iolH	-	-	ko:K06605	-	-	-	-	ko00000	-	-	-	AP_endonuc_2
SRR25158416_k127_3226919_10	1120949.KB903295_gene2349	1.464e-50	182.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DBT5@85008|Micromonosporales	201174|Actinobacteria	S	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_3233987_1	40571.JOEA01000050_gene7496	1.36e-51	186.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria,4EBUX@85010|Pseudonocardiales	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
SRR25158416_k127_3233987_3	953739.SVEN_4118	2.964e-37	143.0	COG3682@1|root,COG3682@2|Bacteria,2IIIT@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158416_k127_3233987_0	1122138.AQUZ01000002_gene2102	7.078e-52	195.0	COG0501@1|root,COG0501@2|Bacteria,2GM27@201174|Actinobacteria,4DUZ8@85009|Propionibacteriales	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158416_k127_3241164_0	525368.HMPREF0591_1878	1.206e-259	809.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,2377M@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158416_k127_3241164_1	479431.Namu_3470	6.61e-137	439.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4EVJ8@85013|Frankiales	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158416_k127_3241164_2	710696.Intca_2843	3.151e-84	283.0	2EGIQ@1|root,33AAX@2|Bacteria,2IBVG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3241164_3	1440774.Y900_028255	1.374e-55	197.0	2DSMY@1|root,33GQS@2|Bacteria,2GS9Y@201174|Actinobacteria,23B40@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
SRR25158416_k127_3245212_0	35754.JNYJ01000064_gene1412	1.471e-209	701.0	COG1112@1|root,COG1198@1|root,COG1112@2|Bacteria,COG1198@2|Bacteria,2GKJW@201174|Actinobacteria,4DBGN@85008|Micromonosporales	201174|Actinobacteria	L	Superfamily I DNA and RNA helicases and helicase subunits	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF3320,DUF4011,DUF559
SRR25158416_k127_3247374_1	1121946.AUAX01000033_gene5697	8.668e-81	270.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4DCUW@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_3247374_0	1121946.AUAX01000033_gene5698	1.932e-129	417.0	COG3832@1|root,COG3832@2|Bacteria,2HQ66@201174|Actinobacteria,4DFVF@85008|Micromonosporales	201174|Actinobacteria	S	Pfam Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR25158416_k127_3247374_2	2002.JOEQ01000020_gene7058	6.599e-13	77.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4EFH8@85012|Streptosporangiales	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158416_k127_3247374_3	1032480.MLP_14590	1.14e-08	57.0	COG1403@1|root,COG1403@2|Bacteria,2IRY0@201174|Actinobacteria,4DREW@85009|Propionibacteriales	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158416_k127_3251211_1	710696.Intca_1075	8.237e-317	975.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4FE8A@85021|Intrasporangiaceae	201174|Actinobacteria	EQ	Hydantoinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158416_k127_3251211_11	42256.RradSPS_0150	1.892e-64	226.0	COG0572@1|root,COG0572@2|Bacteria,2HQC8@201174|Actinobacteria	201174|Actinobacteria	F	belongs to the nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,Cytidylate_kin
SRR25158416_k127_3251211_5	73044.JNXP01000004_gene3081	7.775e-143	464.0	COG3616@1|root,COG3616@2|Bacteria,2GJMB@201174|Actinobacteria	201174|Actinobacteria	E	Alanine racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
SRR25158416_k127_3251211_4	479432.Sros_0566	4.085e-181	578.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4EI7A@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158416_k127_3251211_7	1385518.N798_05250	1.855e-131	426.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4FFY6@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the carbamate kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158416_k127_3251211_3	479431.Namu_5328	8.557e-197	626.0	2DBC4@1|root,2Z8BS@2|Bacteria,2GYBF@201174|Actinobacteria,4ERMM@85013|Frankiales	201174|Actinobacteria	S	Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid	bar	-	3.5.2.1,3.5.2.15	ko:K03383,ko:K19794	ko00240,ko00791,ko01100,ko01120,map00240,map00791,map01100,map01120	-	R02139,R05561,R10777	RC00632,RC00680,RC01423,RC03058	ko00000,ko00001,ko01000	-	-	-	Amido_AtzD_TrzD
SRR25158416_k127_3251211_13	570268.ANBB01000002_gene362	5.225e-31	131.0	COG1404@1|root,COG1404@2|Bacteria,2GMN0@201174|Actinobacteria,4EK90@85012|Streptosporangiales	201174|Actinobacteria	O	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
SRR25158416_k127_3251211_9	408672.NBCG_02665	1.654e-84	291.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4DNG8@85009|Propionibacteriales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158416_k127_3251211_14	875328.JDM601_1821	1.017e-22	98.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,23B83@1762|Mycobacteriaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158416_k127_3251211_12	1210045.ALNP01000018_gene2190	1.374e-58	205.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158416_k127_3251211_10	263358.VAB18032_15170	1.611e-81	281.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4DAJB@85008|Micromonosporales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158416_k127_3251211_2	1120950.KB892768_gene5215	3.703e-201	630.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4DPA8@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158416_k127_3251211_0	1120950.KB892768_gene5214	5.34e-322	1010.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4DPEJ@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158416_k127_3251211_6	367299.JOEE01000010_gene3292	1.241e-139	451.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4FEVG@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158416_k127_3251211_8	1120950.KB892768_gene5202	1.899e-119	394.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4DN1T@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158416_k127_3255572_1	365046.Rta_22515	6.721e-15	80.0	COG0454@1|root,COG0456@2|Bacteria,1PFFT@1224|Proteobacteria,2WC3B@28216|Betaproteobacteria,4AISV@80864|Comamonadaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_3255572_0	929712.KI912613_gene4251	1.721e-31	136.0	COG0500@1|root,COG2226@2|Bacteria,2HQDN@201174|Actinobacteria,4CRY5@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_3255572_2	298655.KI912266_gene6305	3.26e-14	74.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4ERJR@85013|Frankiales	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_3268268_3	1120950.KB892760_gene5721	1.016e-26	121.0	COG2311@1|root,COG2311@2|Bacteria,2GKA8@201174|Actinobacteria,4DQSU@85009|Propionibacteriales	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3268268_2	1120950.KB892760_gene5720	1.01e-60	219.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria,4DREX@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3268268_4	1229203.KI301992_gene1990	2.667e-07	63.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
SRR25158416_k127_3268268_0	1298863.AUEP01000003_gene3094	1.484e-147	479.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,4DQD1@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158416_k127_3268268_1	1169161.KB897717_gene3059	1.226e-80	269.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158416_k127_3270687_1	196162.Noca_2618	3.155e-206	655.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DNTY@85009|Propionibacteriales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158416_k127_3270687_0	1048339.KB913029_gene4817	0.0	1009.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4ERZ3@85013|Frankiales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158416_k127_3270687_2	1246995.AFR_33050	5.894e-52	194.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4D9B5@85008|Micromonosporales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_3288697_0	1274.HX89_00160	1.053e-192	604.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_29,HTH_32
SRR25158416_k127_3288697_2	710421.Mycch_4538	9.838e-08	55.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,2349Y@1762|Mycobacteriaceae	201174|Actinobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_3288697_1	1120950.KB892750_gene6897	5.787e-34	133.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158416_k127_329219_6	408672.NBCG_00078	7.817e-61	214.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DQP2@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158416_k127_329219_2	196162.Noca_0275	1.388e-101	337.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4DPRI@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158416_k127_329219_3	1120934.KB894428_gene1813	2.261e-87	301.0	COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria,4E2QR@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	blaB3	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_329219_0	351607.Acel_2020	1.296e-165	538.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4ERWF@85013|Frankiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158416_k127_329219_8	1122138.AQUZ01000021_gene8593	2.537e-33	130.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4DRSV@85009|Propionibacteriales	201174|Actinobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158416_k127_329219_1	397278.JOJN01000003_gene1887	4.499e-135	445.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4DNG1@85009|Propionibacteriales	201174|Actinobacteria	C	NAD(P) transhydrogenase, alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158416_k127_329219_7	2074.JNYD01000017_gene4322	2.213e-54	201.0	COG5403@1|root,COG5403@2|Bacteria,2IKKK@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158416_k127_329219_5	926554.KI912617_gene4785	5.594e-64	227.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158416_k127_329219_4	1123024.AUII01000014_gene4292	9.291e-75	257.0	COG0262@1|root,COG0262@2|Bacteria,2GJU5@201174|Actinobacteria,4DZI1@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_3298128_30	397278.JOJN01000014_gene3543	5.02e-09	59.0	294UD@1|root,2ZS7J@2|Bacteria,2IEGZ@201174|Actinobacteria,4DPJE@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3298128_9	446471.Xcel_0795	1.325e-160	514.0	COG0582@1|root,COG0582@2|Bacteria,2I0R8@201174|Actinobacteria,4F5MK@85017|Promicromonosporaceae	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_3298128_25	446471.Xcel_0794	8.835e-25	106.0	COG3311@1|root,COG3311@2|Bacteria,2I0TN@201174|Actinobacteria,4F5WR@85017|Promicromonosporaceae	2|Bacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_3298128_1	1120950.KB892749_gene3340	0.0	1066.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4DQ0K@85009|Propionibacteriales	201174|Actinobacteria	T	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158416_k127_3298128_22	1054860.KB913030_gene4418	1.084e-43	165.0	2DA1Q@1|root,32TUF@2|Bacteria,2GKR3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3298128_13	1120950.KB892749_gene3341	5.035e-100	340.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4DQEN@85009|Propionibacteriales	201174|Actinobacteria	T	Domain present in PSD-95, Dlg, and ZO-1/2.	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158416_k127_3298128_21	479432.Sros_8345	7.893e-52	186.0	COG0314@1|root,COG0314@2|Bacteria,2IQ9F@201174|Actinobacteria,4EIYN@85012|Streptosporangiales	201174|Actinobacteria	H	MoaE protein	moaE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
SRR25158416_k127_3298128_10	1123320.KB889672_gene3687	1.379e-148	486.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria	201174|Actinobacteria	H	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158416_k127_3298128_19	1454010.JEOE01000028_gene970	1.482e-62	219.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4F1PC@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158416_k127_3298128_27	754252.PFREUD_09900	8.162e-23	99.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3298128_18	105425.BBPL01000028_gene4102	1.539e-65	237.0	COG0476@1|root,COG0476@2|Bacteria,2GMJI@201174|Actinobacteria,2NGZS@228398|Streptacidiphilus	201174|Actinobacteria	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
SRR25158416_k127_3298128_4	1048339.KB913029_gene771	5.992e-266	827.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4EUNT@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158416_k127_3298128_6	1120950.KB892749_gene3356	1.757e-198	637.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DNKT@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
SRR25158416_k127_3298128_8	298653.Franean1_0937	5.062e-167	538.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE,Phosphodiest
SRR25158416_k127_3298128_23	1123320.KB889672_gene3695	2.031e-36	142.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	-	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
SRR25158416_k127_3298128_3	1120950.KB892749_gene3360	3.514e-274	860.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4DNWV@85009|Propionibacteriales	201174|Actinobacteria	L	HRDC domain	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158416_k127_3298128_14	469371.Tbis_2968	1.139e-98	331.0	COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4DXT4@85010|Pseudonocardiales	201174|Actinobacteria	L	NADH pyrophosphatase	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
SRR25158416_k127_3298128_15	1120950.KB892749_gene3363	1.048e-92	316.0	COG0813@1|root,COG0813@2|Bacteria,2GNT6@201174|Actinobacteria,4DPAS@85009|Propionibacteriales	201174|Actinobacteria	F	Phosphorylase superfamily	deoD	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158416_k127_3298128_16	1123320.KB889672_gene3701	7.916e-83	284.0	COG3568@1|root,COG3568@2|Bacteria,2GP3V@201174|Actinobacteria	201174|Actinobacteria	L	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158416_k127_3298128_7	1122182.KB903813_gene2702	1.892e-178	571.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4DB60@85008|Micromonosporales	201174|Actinobacteria	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234,HTH_5
SRR25158416_k127_3298128_0	1120950.KB892749_gene3376	0.0	1199.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4DP1P@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158416_k127_3298128_2	263358.VAB18032_00220	3.603e-284	907.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4DB8B@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158416_k127_3298128_24	644283.Micau_5577	2.815e-31	125.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria,4DET5@85008|Micromonosporales	201174|Actinobacteria	L	cysteine	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRR25158416_k127_3298128_11	469371.Tbis_3323	6.133e-133	456.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4E4A4@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158416_k127_3298128_12	1445613.JALM01000030_gene5356	9.236e-121	395.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4E1GE@85010|Pseudonocardiales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihB	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158416_k127_3298128_5	1122138.AQUZ01000003_gene643	3.555e-206	649.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4DNCG@85009|Propionibacteriales	201174|Actinobacteria	H	ThiF family	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158416_k127_3298128_20	469371.Tbis_2983	9.448e-62	229.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4DYFE@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158416_k127_3298128_17	1298863.AUEP01000007_gene323	7.706e-77	264.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,4DQBY@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_3298128_26	1054860.KB913030_gene4381	4.855e-23	100.0	2E3M2@1|root,32YJA@2|Bacteria,2GQQW@201174|Actinobacteria	201174|Actinobacteria	S	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRR25158416_k127_3298128_28	1123320.KB889717_gene7646	6.638e-15	75.0	COG2261@1|root,COG2261@2|Bacteria,2IQGD@201174|Actinobacteria	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158416_k127_3302917_1	1033730.CAHG01000013_gene1440	3.203e-167	538.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4DN8C@85009|Propionibacteriales	201174|Actinobacteria	KL	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRR25158416_k127_3302917_3	35754.JNYJ01000005_gene5543	1.898e-95	323.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4D8KV@85008|Micromonosporales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158416_k127_3302917_7	1380393.JHVP01000009_gene1392	9.875e-09	63.0	COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria,4ETIZ@85013|Frankiales	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158416_k127_3302917_4	1120950.KB892707_gene4594	2.287e-78	264.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4DQJU@85009|Propionibacteriales	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158416_k127_3302917_0	1121926.AXWO01000001_gene3514	0.0	1650.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4EY34@85014|Glycomycetales	201174|Actinobacteria	F	Class II vitamin B12-dependent ribonucleotide reductase	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158416_k127_3302917_6	1229780.BN381_80310	9.217e-30	124.0	COG3945@1|root,COG3945@2|Bacteria,2I4J6@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_3302917_5	1121272.KB903261_gene6169	6.085e-50	185.0	COG0537@1|root,COG0537@2|Bacteria,2HNIX@201174|Actinobacteria,4DAR0@85008|Micromonosporales	201174|Actinobacteria	FG	adenosine 5'-monophosphoramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3302917_2	1449044.JMLE01000015_gene816	2.407e-129	428.0	COG0436@1|root,COG0436@2|Bacteria,2GPM3@201174|Actinobacteria	201174|Actinobacteria	E	Pfam Aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158416_k127_3305351_3	1122611.KB903974_gene2941	1.308e-125	407.0	COG1132@1|root,COG1132@2|Bacteria,2GJ8B@201174|Actinobacteria,4EGR8@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_3305351_2	1223544.GSI01S_09_00440	1.881e-179	576.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4GFZ2@85026|Gordoniaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_3305351_1	1120950.KB892783_gene342	8.714e-190	597.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4DN1G@85009|Propionibacteriales	201174|Actinobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158416_k127_3305351_0	593907.Celgi_0885	7.436e-249	783.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4F0EC@85016|Cellulomonadaceae	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158416_k127_3305351_4	28042.GU90_06065	7.659e-82	276.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DXE7@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	dapC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv0858c	Aminotran_1_2
SRR25158416_k127_3308673_0	1244869.H261_16907	4.574e-39	161.0	28MHU@1|root,2ZAUM@2|Bacteria,1R3RK@1224|Proteobacteria,2TTR4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3318392_4	55952.BU52_33305	2.068e-05	48.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_38,rve
SRR25158416_k127_3318392_0	312284.A20C1_09614	7.528e-170	545.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase domain protein	xyoA	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158416_k127_3318392_2	469383.Cwoe_4437	1.328e-31	135.0	COG1695@1|root,COG1695@2|Bacteria,2IMV9@201174|Actinobacteria,4CU0V@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158416_k127_3318392_1	1298880.AUEV01000003_gene3531	7.894e-55	194.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3318392_3	1278073.MYSTI_02803	1.734e-16	87.0	COG0412@1|root,COG1506@1|root,COG0412@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	BAAT_C,DLH,PD40,Peptidase_S9
SRR25158416_k127_333237_7	479435.Kfla_1447	5.596e-47	176.0	COG2246@1|root,COG2246@2|Bacteria,2IFFV@201174|Actinobacteria,4DRHR@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM GtrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158416_k127_333237_2	1123320.KB889719_gene7401	1.468e-153	495.0	COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158416_k127_333237_5	1245475.ANAE01000002_gene111	1.147e-59	222.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4EIVH@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3275c	AIRC
SRR25158416_k127_333237_6	494419.ALPM01000077_gene1631	3.603e-48	177.0	COG1832@1|root,COG1832@2|Bacteria,2IHSP@201174|Actinobacteria,1WCJG@1268|Micrococcaceae	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158416_k127_333237_1	269800.Tfu_1647	9.956e-187	591.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EHDP@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	acdA3	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_333237_0	67267.JNXT01000088_gene6376	2.439e-191	607.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158416_k127_333237_3	1120950.KB892759_gene6261	3.385e-102	355.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4DPY2@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158416_k127_333237_4	285535.JOEY01000016_gene3615	1.09e-70	252.0	COG1607@1|root,COG1607@2|Bacteria,2GK6X@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA hydrolase	-	-	3.1.2.23	ko:K01075,ko:K10806	ko00130,ko00362,ko01040,ko01100,ko01110,ko01120,map00130,map00362,map01040,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158416_k127_333237_8	1033730.CAHG01000002_gene2882	5.738e-05	49.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4DPE8@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158416_k127_3340139_6	1120950.KB892752_gene6157	6.48e-84	282.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4DNWF@85009|Propionibacteriales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158416_k127_3340139_11	1463856.JOHY01000006_gene210	7.532e-13	80.0	29917@1|root,2ZW4S@2|Bacteria,2IJQY@201174|Actinobacteria	201174|Actinobacteria	S	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3
SRR25158416_k127_3340139_5	105422.BBPM01000026_gene4062	2.39e-95	329.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,2NH0G@228398|Streptacidiphilus	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SRR25158416_k127_3340139_0	367299.JOEE01000007_gene175	2.313e-227	709.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4FE8B@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158416_k127_3340139_10	479435.Kfla_5695	3.056e-30	126.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4DS5K@85009|Propionibacteriales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158416_k127_3340139_8	263358.VAB18032_09185	9.089e-73	250.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4DCTN@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158416_k127_3340139_3	1137269.AZWL01000034_gene2492	1.007e-110	366.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158416_k127_3340139_4	1123065.ATWL01000020_gene3570	2.094e-110	364.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria	201174|Actinobacteria	L	uracil-DNA glycosylase	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158416_k127_3340139_1	1120950.KB892752_gene6183	5.054e-205	645.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4DPIA@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158416_k127_3340139_2	1306990.BARG01000014_gene1167	9.961e-155	502.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158416_k127_3340139_9	110319.CF8_3158	2.171e-58	209.0	COG2716@1|root,COG2716@2|Bacteria,2IS2K@201174|Actinobacteria	201174|Actinobacteria	E	ACT domain	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
SRR25158416_k127_3340139_7	1464048.JNZS01000002_gene499	1.253e-74	260.0	COG0242@1|root,COG0242@2|Bacteria,2HMJS@201174|Actinobacteria,4DBU9@85008|Micromonosporales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158416_k127_3340139_12	40571.JOEA01000008_gene2697	6.935e-05	45.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4E13I@85010|Pseudonocardiales	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158416_k127_3342411_0	101510.RHA1_ro00749	4.609e-212	668.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4FU00@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158416_k127_3342411_1	1121272.KB903252_gene1149	3.372e-39	148.0	COG3342@1|root,COG3342@2|Bacteria,2HWBG@201174|Actinobacteria,4DA1Q@85008|Micromonosporales	201174|Actinobacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
SRR25158416_k127_3379659_29	543632.JOJL01000056_gene318	1.168e-15	80.0	COG0358@1|root,COG0358@2|Bacteria,2IF71@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_3
SRR25158416_k127_3379659_18	543632.JOJL01000056_gene318	2.139e-60	218.0	COG0358@1|root,COG0358@2|Bacteria,2IF71@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_2,Toprim_3
SRR25158416_k127_3379659_30	1445613.JALM01000024_gene4398	4.123e-12	74.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4E2E6@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_3379659_31	222534.KB893761_gene3562	7.52e-06	52.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4EU5A@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_3379659_19	1122138.AQUZ01000005_gene2670	1.338e-50	185.0	2BIEE@1|root,32T9G@2|Bacteria,2I86Y@201174|Actinobacteria,4DWJ9@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3379659_14	1068978.AMETH_4939	1.186e-90	306.0	COG1051@1|root,COG1051@2|Bacteria,2I2YK@201174|Actinobacteria,4E3FE@85010|Pseudonocardiales	201174|Actinobacteria	F	ADP-ribose pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158416_k127_3379659_12	28444.JODQ01000003_gene4715	1.3e-96	324.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158416_k127_3379659_10	1120950.KB892708_gene4366	9.111e-100	346.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DN3T@85009|Propionibacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158416_k127_3379659_15	196162.Noca_2579	1.641e-83	284.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4DNJB@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158416_k127_3379659_5	351607.Acel_1156	4.165e-134	437.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4ERTI@85013|Frankiales	201174|Actinobacteria	O	PFAM Band 7 protein	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158416_k127_3379659_24	1120950.KB892708_gene4358	1.615e-39	151.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria,4DRK6@85009|Propionibacteriales	201174|Actinobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158416_k127_3379659_7	110319.CF8_2100	2.111e-116	383.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4DNDT@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158416_k127_3379659_4	469371.Tbis_0225	1.244e-149	483.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4E15F@85010|Pseudonocardiales	201174|Actinobacteria	ET	phosphoserine phosphatase	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
SRR25158416_k127_3379659_25	1476876.JOJO01000033_gene3905	2.807e-39	151.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria	201174|Actinobacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158416_k127_3379659_6	1123322.KB904682_gene4728	4.481e-122	395.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3379659_8	105422.BBPM01000073_gene29	6.271e-106	347.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,2NG0C@228398|Streptacidiphilus	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3379659_26	1172180.KB911778_gene4733	9.828e-26	115.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158416_k127_3379659_28	1386089.N865_08035	3.944e-16	83.0	2EGIC@1|root,33AAH@2|Bacteria,2GQ88@201174|Actinobacteria,4FHIH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3099)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3099
SRR25158416_k127_3379659_3	1380346.JNIH01000005_gene3064	1.38e-159	508.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158416_k127_3379659_17	1120950.KB892707_gene4686	6.321e-63	227.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,4DR52@85009|Propionibacteriales	201174|Actinobacteria	S	SURF1 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
SRR25158416_k127_3379659_0	749414.SBI_08234	2.818e-258	814.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158416_k127_3379659_20	1120949.KB903306_gene7629	2.144e-47	177.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4DF8Y@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_3379659_11	1048339.KB913029_gene4317	1.531e-99	330.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158416_k127_3379659_13	1048339.KB913029_gene4318	9.083e-95	320.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EUCD@85013|Frankiales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3379659_2	471852.Tcur_2241	6.626e-258	813.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EFP3@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158416_k127_3379659_27	1214101.BN159_6686	3.09e-25	108.0	2E4I7@1|root,32ZDA@2|Bacteria,2IQBB@201174|Actinobacteria	201174|Actinobacteria	S	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3379659_1	1048339.KB913029_gene4326	3.214e-258	805.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4ES5N@85013|Frankiales	201174|Actinobacteria	S	PFAM ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158416_k127_3379659_9	68223.JNZY01000029_gene44	3.243e-103	343.0	COG2321@1|root,COG2321@2|Bacteria,2H3UT@201174|Actinobacteria	201174|Actinobacteria	S	Neutral zinc metallopeptidase	ypfJ	GO:0005575,GO:0005576	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158416_k127_3379659_22	1120950.KB892707_gene4675	1.248e-41	160.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4DSED@85009|Propionibacteriales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158416_k127_3379659_16	1120950.KB892707_gene4672	1.586e-82	284.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4DQVP@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	bioM	-	-	ko:K16784	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25.1	-	-	ABC_tran
SRR25158416_k127_3379659_21	1122611.KB903940_gene1865	2.298e-45	181.0	COG0619@1|root,COG0619@2|Bacteria,2IQMQ@201174|Actinobacteria,4EJZN@85012|Streptosporangiales	201174|Actinobacteria	P	Cobalt transport protein	bioN	-	-	ko:K16783	ko02010,map02010	M00581	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25.1	-	-	CbiQ
SRR25158416_k127_3379659_23	1214101.BN159_5558	1.123e-40	155.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158416_k127_3381680_2	1075090.GOAMR_58_00330	2.335e-35	136.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4GENK@85026|Gordoniaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_3381680_0	1122138.AQUZ01000022_gene8702	5.494e-261	811.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DP4S@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158416_k127_3381680_1	66377.JOBH01000006_gene257	6.167e-45	163.0	COG1028@1|root,COG1028@2|Bacteria,2I48H@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158416_k127_338246_8	1120959.ATXF01000005_gene1372	1.242e-54	199.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4FMXE@85023|Microbacteriaceae	201174|Actinobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158416_k127_338246_18	211114.JOEF01000032_gene1981	9.117e-12	74.0	2E39G@1|root,32Y91@2|Bacteria,2GQNT@201174|Actinobacteria,4E5VN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_338246_12	469383.Cwoe_5147	4.216e-42	159.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158416_k127_338246_13	1122182.KB903814_gene3323	3.044e-39	160.0	2CDJQ@1|root,2Z7JX@2|Bacteria,2IB9M@201174|Actinobacteria,4DF1K@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_338246_5	1089545.KB913037_gene619	7.979e-88	301.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4E10U@85010|Pseudonocardiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158416_k127_338246_17	882083.SacmaDRAFT_0472	1.445e-15	81.0	2CIE6@1|root,349NW@2|Bacteria,2GXDZ@201174|Actinobacteria,4ED89@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_338246_15	1240349.ANGC01000052_gene4130	3.876e-30	132.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4FXDK@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_338246_1	266117.Rxyl_2662	2.127e-138	449.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria	201174|Actinobacteria	C	Acetamidase formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR25158416_k127_338246_10	1380354.JIAN01000005_gene2816	7.364e-49	180.0	arCOG13016@1|root,335CN@2|Bacteria,2GJJU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_338246_20	66874.JOFS01000029_gene1941	3.484e-06	53.0	arCOG13016@1|root,335CN@2|Bacteria,2GJJU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_338246_2	1313172.YM304_02680	9.53e-109	359.0	COG0258@1|root,COG0258@2|Bacteria,2H2A3@201174|Actinobacteria	201174|Actinobacteria	L	5'-3' exonuclease, C-terminal SAM fold	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158416_k127_338246_11	215803.DB30_8482	1.498e-43	161.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,430Y1@68525|delta/epsilon subdivisions,2WVU4@28221|Deltaproteobacteria,2YVFD@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_338246_9	405948.SACE_5772	5.363e-50	185.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4E60A@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_338246_7	40571.JOEA01000009_gene3302	8.702e-71	241.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4E57U@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_338246_19	313589.JNB_00365	3.617e-07	58.0	COG3832@1|root,COG3832@2|Bacteria,2IFGN@201174|Actinobacteria,4FH38@85021|Intrasporangiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_338246_16	1122138.AQUZ01000078_gene6115	5.331e-21	103.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,4DV8G@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158416_k127_338246_14	1206101.AZXC01000013_gene929	2.563e-32	130.0	COG3832@1|root,COG3832@2|Bacteria,2GSCI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_338246_3	862751.SACTE_1456	4.992e-96	328.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158416_k127_338246_4	313589.JNB_14123	5.965e-92	320.0	COG1075@1|root,COG1075@2|Bacteria,2I8WC@201174|Actinobacteria,4FF4X@85021|Intrasporangiaceae	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_338246_6	909613.UO65_0918	2.693e-72	277.0	COG4995@1|root,COG4995@2|Bacteria,2IG9P@201174|Actinobacteria,4EBK9@85010|Pseudonocardiales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158416_k127_338246_0	253839.SSNG_06730	1.801e-247	787.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
SRR25158416_k127_3383026_15	591157.SSLG_03965	5.365e-08	56.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158416_k127_3383026_9	591157.SSLG_03965	6.7e-117	387.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158416_k127_3383026_2	1120950.KB892779_gene968	1.047e-233	735.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DPY1@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158416_k127_3383026_11	471852.Tcur_4414	8.281e-90	314.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4EHWV@85012|Streptosporangiales	201174|Actinobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158416_k127_3383026_3	479435.Kfla_6293	2.887e-231	721.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4DPP6@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158416_k127_3383026_0	1120950.KB892779_gene965	0.0	1073.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4DNGW@85009|Propionibacteriales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158416_k127_3383026_6	1120950.KB892779_gene964	1.483e-165	541.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4DNAD@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
SRR25158416_k127_3383026_10	1120950.KB892779_gene963	1.685e-92	308.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4DP1W@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
SRR25158416_k127_3383026_12	1240349.ANGC01000026_gene3701	5.023e-81	278.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4FX5D@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158416_k127_3383026_13	1223523.H340_08163	1.211e-40	156.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158416_k127_3383026_1	1120950.KB892779_gene960	6.981e-271	853.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4DP65@85009|Propionibacteriales	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158416_k127_3383026_5	1122138.AQUZ01000056_gene6951	3.803e-173	581.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4DPXE@85009|Propionibacteriales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158416_k127_3383026_4	1123320.KB889574_gene5648	5.599e-201	637.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158416_k127_3383026_8	1120950.KB892779_gene957	3.841e-117	388.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4DNPE@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158416_k127_3383026_7	1246448.ANAZ01000048_gene3281	7.05e-135	449.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
SRR25158416_k127_3383026_14	862751.SACTE_3915	1.311e-17	83.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158416_k127_3396470_16	526225.Gobs_2792	1.22e-11	66.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4ES4E@85013|Frankiales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158416_k127_3396470_13	1713.JOFV01000035_gene1354	5.494e-57	205.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4F1ZJ@85016|Cellulomonadaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,LZ_Tnp_IS481,rve
SRR25158416_k127_3396470_15	1211815.CBYP010000074_gene3595	6.862e-16	79.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	LZ_Tnp_IS481,rve
SRR25158416_k127_3396470_2	1304275.C41B8_13955	8.164e-237	740.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,1RNIZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the mannitol dehydrogenase family	mtlD	-	1.1.1.57,1.1.1.67,2.7.1.17	ko:K00040,ko:K00045,ko:K00854	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014,M00061	R00868,R01639,R02454	RC00002,RC00085,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
SRR25158416_k127_3396470_3	471857.Svir_04580	6.654e-174	557.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4DXQ6@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158416_k127_3396470_14	1123024.AUII01000006_gene4577	6.781e-29	120.0	COG1396@1|root,COG1396@2|Bacteria,2GPQW@201174|Actinobacteria,4EC3K@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158416_k127_3396470_10	1123023.JIAI01000021_gene2369	9.606e-115	374.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4E0KE@85010|Pseudonocardiales	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158416_k127_3396470_4	1246995.AFR_20685	9.57e-154	491.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria,4DBGZ@85008|Micromonosporales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	iolC	-	2.7.1.45,2.7.1.92	ko:K00874,ko:K03338	ko00030,ko00562,ko01100,ko01120,ko01200,map00030,map00562,map01100,map01120,map01200	M00061,M00308,M00631	R01541,R05661	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158416_k127_3396470_6	2074.JNYD01000024_gene2874	4.768e-139	449.0	COG1830@1|root,COG1830@2|Bacteria,2GKTN@201174|Actinobacteria,4DYYW@85010|Pseudonocardiales	201174|Actinobacteria	G	deoxyribose-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3396470_9	1123023.JIAI01000021_gene2366	1.181e-121	403.0	COG3718@1|root,COG3718@2|Bacteria,2GM8S@201174|Actinobacteria,4DY8G@85010|Pseudonocardiales	201174|Actinobacteria	G	KduI/IolB family	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158416_k127_3396470_0	33876.JNXY01000016_gene6911	6.957e-297	921.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria,4D98S@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the TPP enzyme family	iolD	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158416_k127_3396470_1	543632.JOJL01000039_gene1647	1.906e-263	818.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4D8Q2@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_3396470_7	443218.AS9A_3970	1.312e-125	409.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,235HH@1762|Mycobacteriaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_3396470_12	2074.JNYD01000024_gene2873	3.187e-106	379.0	COG1879@1|root,COG1879@2|Bacteria,2GKIJ@201174|Actinobacteria,4DY62@85010|Pseudonocardiales	201174|Actinobacteria	G	Periplasmic binding protein domain	iolTA	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
SRR25158416_k127_3396470_5	526225.Gobs_2771	6.552e-153	490.0	COG1172@1|root,COG1172@2|Bacteria,2GM9E@201174|Actinobacteria,4ES5D@85013|Frankiales	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	iolTB	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158416_k127_3396470_8	526225.Gobs_2770	1.815e-125	409.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4ETUW@85013|Frankiales	201174|Actinobacteria	G	Monosaccharide ABC transporter ATP-binding protein, CUT2 family	iolTC	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158416_k127_3396470_11	1246995.AFR_20730	3.667e-107	361.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DBT5@85008|Micromonosporales	201174|Actinobacteria	S	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_3398294_14	211114.JOEF01000035_gene1569	7.288e-83	284.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4DY9W@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158416_k127_3398294_15	1306406.ASHX01000002_gene5478	9.881e-80	269.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3398294_22	1169161.KB897728_gene807	3.492e-53	190.0	COG3938@1|root,COG3938@2|Bacteria,2GM47@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the proline racemase family	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
SRR25158416_k127_3398294_10	526225.Gobs_2317	9.763e-109	354.0	COG3938@1|root,COG3938@2|Bacteria,2GM47@201174|Actinobacteria,4EUM0@85013|Frankiales	201174|Actinobacteria	E	Proline racemase	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
SRR25158416_k127_3398294_6	526225.Gobs_2316	3.288e-138	447.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4EVQK@85013|Frankiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158416_k127_3398294_29	1211815.CBYP010000028_gene1030	2.697e-17	84.0	2DRBI@1|root,33B4D@2|Bacteria,2GWXK@201174|Actinobacteria,4ETJ0@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3398294_9	35754.JNYJ01000065_gene5685	3.722e-113	387.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4D9SS@85008|Micromonosporales	201174|Actinobacteria	S	n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158416_k127_3398294_2	1123519.PSJM300_06085	7.833e-213	671.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RN5B@1236|Gammaproteobacteria,1Z1UJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	alaA	GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158416_k127_3398294_16	2045.KR76_08180	5.848e-70	252.0	COG1524@1|root,COG1524@2|Bacteria,2HY6Q@201174|Actinobacteria,4DT1Q@85009|Propionibacteriales	201174|Actinobacteria	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158416_k127_3398294_18	1120950.KB892745_gene2892	8.172e-62	221.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158416_k127_3398294_4	469383.Cwoe_1072	5.528e-190	607.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4CRKJ@84995|Rubrobacteria	84995|Rubrobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18
SRR25158416_k127_3398294_20	1120936.KB907212_gene5058	7.302e-58	206.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4EJA2@85012|Streptosporangiales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158416_k127_3398294_27	926564.KI911664_gene791	5.371e-18	88.0	2EEMB@1|root,338F8@2|Bacteria,2GRKB@201174|Actinobacteria,4F4VE@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3398294_0	1120950.KB892747_gene3715	0.0	1860.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria,4DNZP@85009|Propionibacteriales	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	oplA	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0266c	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158416_k127_3398294_23	1120954.ATXE01000001_gene1800	4.064e-51	189.0	28MIG@1|root,2ZAV8@2|Bacteria,2IGFB@201174|Actinobacteria,4DQAF@85009|Propionibacteriales	201174|Actinobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
SRR25158416_k127_3398294_13	1298863.AUEP01000009_gene90	3.193e-89	300.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4DQD7@85009|Propionibacteriales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158416_k127_3398294_8	1120936.KB907218_gene3421	2.77e-125	421.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4EFGJ@85012|Streptosporangiales	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_3398294_11	935839.JAGJ01000002_gene874	3.783e-100	332.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4F4CC@85017|Promicromonosporaceae	201174|Actinobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_3398294_26	585531.HMPREF0063_12241	2.417e-30	125.0	2BYGI@1|root,333FU@2|Bacteria,2GRMH@201174|Actinobacteria,4DSJS@85009|Propionibacteriales	201174|Actinobacteria	S	Subtilisin inhibitor-like	-	-	-	-	-	-	-	-	-	-	-	-	SSI
SRR25158416_k127_3398294_3	390989.JOEG01000004_gene3736	4.836e-195	615.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4DB9A@85008|Micromonosporales	201174|Actinobacteria	C	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158416_k127_3398294_32	469371.Tbis_3562	1.592e-09	66.0	28SVW@1|root,2ZF5E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3398294_24	479435.Kfla_7001	9.129e-42	154.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4DRPR@85009|Propionibacteriales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158416_k127_3398294_17	1298863.AUEP01000006_gene3451	4.102e-69	243.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4DQ95@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158416_k127_3398294_25	1463864.JOGO01000016_gene4552	4.061e-33	139.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158416_k127_3398294_19	1048339.KB913029_gene1600	7.115e-61	214.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4ESST@85013|Frankiales	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158416_k127_3398294_5	44060.JODL01000037_gene3405	1.008e-141	467.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria	201174|Actinobacteria	V	MATE efflux family protein	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158416_k127_3398294_1	1121017.AUFG01000025_gene182	1.59e-260	822.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4FFWS@85021|Intrasporangiaceae	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158416_k127_3398294_7	219305.MCAG_04362	2.056e-127	418.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DAPP@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70 region 2	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	NTF2,Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158416_k127_3398294_31	1123319.AUBE01000006_gene3102	5.904e-11	68.0	2B42Y@1|root,31WTH@2|Bacteria,2INUX@201174|Actinobacteria	201174|Actinobacteria	S	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158416_k127_3398294_21	1123319.AUBE01000001_gene1851	3.886e-56	199.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3398294_28	1122138.AQUZ01000083_gene3514	1.668e-17	94.0	COG3386@1|root,COG3386@2|Bacteria,2HDRT@201174|Actinobacteria,4DNUM@85009|Propionibacteriales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158416_k127_3398294_33	479435.Kfla_4207	0.0006472	48.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,Cupin_7
SRR25158416_k127_3398294_12	471852.Tcur_0287	3.642e-94	317.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4EFKV@85012|Streptosporangiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158416_k127_3398294_30	471852.Tcur_1276	3.765e-17	85.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4EFKV@85012|Streptosporangiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158416_k127_3399768_0	926561.KB900617_gene1594	9.161e-85	294.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WBJB@53433|Halanaerobiales	186801|Clostridia	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR25158416_k127_3399768_6	264732.Moth_1796	7.741e-08	57.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42G18@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_3399768_3	469383.Cwoe_1615	9.097e-63	231.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4CSU4@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158416_k127_3399768_1	591157.SSLG_00892	9.006e-81	276.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3399768_4	1038859.AXAU01000001_gene3025	1.583e-26	119.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria	1224|Proteobacteria	Q	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,Ubie_methyltran
SRR25158416_k127_3399768_5	381666.H16_A2216	5.245e-24	109.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2VTNF@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR25158416_k127_3399768_2	1236902.ANAS01000062_gene3015	7.305e-65	226.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4ENGS@85012|Streptosporangiales	201174|Actinobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158416_k127_3408828_32	367299.JOEE01000007_gene213	5.117e-22	106.0	COG1073@1|root,COG1073@2|Bacteria,2HXHB@201174|Actinobacteria,4FGVQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_3408828_31	562970.Btus_3146	6.793e-25	120.0	COG4625@1|root,COG5492@1|root,COG4625@2|Bacteria,COG5492@2|Bacteria,1V72Z@1239|Firmicutes	1239|Firmicutes	N	PFAM S-layer domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
SRR25158416_k127_3408828_34	1123075.AUDP01000026_gene446	1.12e-12	73.0	COG1686@1|root,COG4767@1|root,COG1686@2|Bacteria,COG4767@2|Bacteria,1UZY6@1239|Firmicutes,24DM6@186801|Clostridia,3WJS8@541000|Ruminococcaceae	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11,VanZ
SRR25158416_k127_3408828_39	313589.JNB_06654	2.5e-06	55.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4FEUS@85021|Intrasporangiaceae	201174|Actinobacteria	U	Flp pilus assembly protein ATPase CpaF	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158416_k127_3408828_29	1121019.AUMN01000004_gene1479	2.96e-35	137.0	2FEGA@1|root,346FV@2|Bacteria,2H7YE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3408828_18	1128421.JAGA01000001_gene2297	1.351e-99	329.0	COG0262@1|root,COG0262@2|Bacteria,2NRYY@2323|unclassified Bacteria	2|Bacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_3408828_40	330084.JNYZ01000027_gene8130	0.0003408	53.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3408828_26	1386089.N865_05860	3.877e-44	166.0	28RB9@1|root,2ZDQU@2|Bacteria,2GZQK@201174|Actinobacteria,4FIZG@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3408828_4	298653.Franean1_2313	9.998e-186	590.0	28KUD@1|root,2ZAB6@2|Bacteria,2IACK@201174|Actinobacteria,4EUQM@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3408828_1	479431.Namu_4887	1.26e-313	974.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4ERC9@85013|Frankiales	201174|Actinobacteria	G	PFAM glycoside hydrolase family 77	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158416_k127_3408828_12	710687.KI912270_gene4527	1.221e-125	421.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria,23FHB@1762|Mycobacteriaceae	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158416_k127_3408828_14	1122138.AQUZ01000056_gene6929	2.176e-109	358.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DPH5@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3408828_25	1380356.JNIK01000011_gene1782	8.184e-54	196.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_3408828_3	710686.Mycsm_02443	3.553e-190	606.0	COG0531@1|root,COG0531@2|Bacteria,2I49Z@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease,AA_permease_2
SRR25158416_k127_3408828_9	40571.JOEA01000012_gene1007	4.049e-155	503.0	COG0174@1|root,COG0174@2|Bacteria,2GM3K@201174|Actinobacteria,4DXD6@85010|Pseudonocardiales	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	glnA4	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158416_k127_3408828_23	1449976.KALB_1416	1.957e-59	217.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4E32I@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158416_k127_3408828_6	1283299.AUKG01000001_gene2462	1.38e-178	575.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPFP@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_3408828_16	42256.RradSPS_2748	6.935e-102	337.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CPC2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158416_k127_3408828_21	446462.Amir_2080	2.219e-74	257.0	COG2186@1|root,COG2186@2|Bacteria,2HQFA@201174|Actinobacteria,4E1DV@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158416_k127_3408828_2	1123322.KB904661_gene4215	1.472e-198	634.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158416_k127_3408828_33	1449346.JQMO01000003_gene6687	1.629e-18	91.0	2EGVE@1|root,33AMN@2|Bacteria,2GQWM@201174|Actinobacteria,2M3Q0@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3408828_10	1120950.KB892708_gene4395	2.313e-142	458.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DPF5@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_3408828_8	211114.JOEF01000035_gene1459	1.895e-160	512.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3408828_15	935866.JAER01000007_gene337	4.985e-102	344.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4DN4Z@85009|Propionibacteriales	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158416_k127_3408828_27	1121926.AXWO01000002_gene1471	1.507e-38	162.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4EXVH@85014|Glycomycetales	201174|Actinobacteria	M	Peptidase family M23	pdc2	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158416_k127_3408828_22	1123023.JIAI01000016_gene3478	1.471e-71	248.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,4DXVM@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Phosphoglycerate mutase	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158416_k127_3408828_24	479435.Kfla_3808	2.307e-57	205.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4DQQ2@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158416_k127_3408828_20	414996.IL38_15490	3.57e-87	297.0	COG5032@1|root,COG5032@2|Bacteria,2GME7@201174|Actinobacteria,408AE@622450|Actinopolysporales	201174|Actinobacteria	BDLTU	Phosphatidylinositol	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3408828_7	471852.Tcur_2287	3.843e-167	535.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,4EH1Y@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
SRR25158416_k127_3408828_13	1306174.JODP01000002_gene5748	1.228e-124	405.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158416_k127_3408828_0	1003195.SCAT_5155	0.0	1749.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria	201174|Actinobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158416_k127_3408828_5	1211815.CBYP010000029_gene1265	5.578e-183	591.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4EU9T@85013|Frankiales	201174|Actinobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158416_k127_3408828_11	1146883.BLASA_0481	4.131e-141	454.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4ETRM@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158416_k127_3408828_17	926564.KI911656_gene1534	2.793e-101	338.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4F5Z2@85017|Promicromonosporaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	appCC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158416_k127_3408828_19	219305.MCAG_02487	3.215e-94	313.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4D9JJ@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	appD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158416_k127_3411029_3	1172188.KB911822_gene802	1.012e-06	54.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria,4FFRG@85021|Intrasporangiaceae	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR25158416_k127_3411029_1	1150398.JIBJ01000003_gene1737	2.453e-233	729.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,1W7WN@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158416_k127_3411029_2	1961.JOAK01000032_gene2632	7.116e-205	656.0	COG4425@1|root,COG4425@2|Bacteria,2GKB5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158416_k127_3411029_0	679926.Mpet_2428	2.654e-237	747.0	COG0076@1|root,arCOG00027@2157|Archaea,2XWF7@28890|Euryarchaeota,2NA8Z@224756|Methanomicrobia	224756|Methanomicrobia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158416_k127_343547_1	1101188.KI912155_gene2082	1.011e-138	446.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,1W8Z4@1268|Micrococcaceae	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158416_k127_343547_14	485913.Krac_11430	2.615e-07	54.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	2|Bacteria	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158416_k127_343547_4	749414.SBI_00441	1.656e-114	379.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_343547_11	590998.Celf_0456	3.013e-16	85.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_343547_8	1120949.KB903357_gene4838	1.245e-30	127.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158416_k127_343547_3	1120950.KB892754_gene6009	1.457e-123	402.0	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria,4DQCP@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_343547_5	543632.JOJL01000013_gene9412	1.674e-53	193.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4DG3V@85008|Micromonosporales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_343547_6	1268072.PSAB_02225	5.796e-45	168.0	COG0599@1|root,COG0599@2|Bacteria,1VWSB@1239|Firmicutes,4HJ1V@91061|Bacilli,276HN@186822|Paenibacillaceae	91061|Bacilli	S	Carboxymuconolactone decarboxylase family	yphJ	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158416_k127_343547_2	1246995.AFR_22090	1.045e-138	444.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
SRR25158416_k127_343547_7	1032480.MLP_09550	1.543e-31	129.0	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria,4DQCP@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_343547_10	1032480.MLP_09550	9.757e-20	96.0	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria,4DQCP@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_343547_12	926569.ANT_29180	5.033e-15	86.0	COG4334@1|root,COG4334@2|Bacteria,2G8RW@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158416_k127_343547_13	653045.Strvi_5474	2.266e-10	64.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158416_k127_343547_9	749414.SBI_00441	1.334e-29	130.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_343547_0	485913.Krac_11430	1.408e-192	618.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	2|Bacteria	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158416_k127_343735_2	1283283.ATXA01000019_gene2944	4.062e-08	64.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4EWWQ@85013|Frankiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_343735_1	1089545.KB913037_gene798	8.649e-40	158.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_343735_0	1089545.KB913037_gene798	1.561e-76	266.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3445265_1	1304865.JAGF01000001_gene2622	1.211e-74	258.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_3445265_0	1033730.CAHG01000016_gene541	1.999e-75	264.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Glyco_hydro_2,Virul_fac_BrkB
SRR25158416_k127_3450380_2	1123024.AUII01000044_gene605	4.403e-142	455.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DZ9U@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158416_k127_3450380_7	1122138.AQUZ01000004_gene891	4.845e-39	148.0	COG3080@1|root,COG3080@2|Bacteria,2IMEN@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1555	Fumarate_red_D
SRR25158416_k127_3450380_6	1123024.AUII01000011_gene4420	2.003e-39	152.0	COG3029@1|root,COG3029@2|Bacteria,2IQ2Z@201174|Actinobacteria	201174|Actinobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
SRR25158416_k127_3450380_3	1122138.AQUZ01000004_gene889	3.738e-127	411.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4DPU6@85009|Propionibacteriales	201174|Actinobacteria	C	Succinate dehydrogenase fumarate reductase	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
SRR25158416_k127_3450380_0	1123024.AUII01000011_gene4422	1.162e-293	911.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DZPA@85010|Pseudonocardiales	201174|Actinobacteria	C	succinate dehydrogenase	frdA	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00244,ko:K00278	ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1552	FAD_binding_2,Succ_DH_flav_C
SRR25158416_k127_3450380_1	1120950.KB892760_gene5788	2.663e-180	575.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4DNHH@85009|Propionibacteriales	201174|Actinobacteria	F	Adenosine/AMP deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158416_k127_3450380_8	1048339.KB913029_gene1942	7.119e-21	98.0	2BJJG@1|root,32DWK@2|Bacteria,2INK8@201174|Actinobacteria,4EVWK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3450380_5	313589.JNB_17968	8.915e-42	167.0	COG2323@1|root,COG2323@2|Bacteria,2IIPT@201174|Actinobacteria,4FI3R@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
SRR25158416_k127_3450380_4	1304865.JAGF01000001_gene2008	8.697e-56	199.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,2GJ5U@201174|Actinobacteria,4F0GJ@85016|Cellulomonadaceae	201174|Actinobacteria	C	belongs to the CobB CobQ family	pta	GO:0005575,GO:0005576	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
SRR25158416_k127_3450394_6	1306174.JODP01000024_gene4098	4.751e-74	262.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria	201174|Actinobacteria	L	ErfK YbiS YcfS YnhG family protein	lppS	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0019538,GO:0030203,GO:0030312,GO:0042546,GO:0043170,GO:0044085,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158416_k127_3450394_2	1120950.KB892762_gene5445	6.133e-142	476.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria,4DNG9@85009|Propionibacteriales	201174|Actinobacteria	S	TAP-like protein	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158416_k127_3450394_3	479435.Kfla_0591	1.405e-134	433.0	COG1774@1|root,COG1774@2|Bacteria,2HYDT@201174|Actinobacteria,4DT53@85009|Propionibacteriales	201174|Actinobacteria	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
SRR25158416_k127_3450394_4	479435.Kfla_0588	1.646e-133	441.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4DNVR@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158416_k127_3450394_8	1996.JOFO01000022_gene2604	4.903e-64	226.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4EFST@85012|Streptosporangiales	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Thymidylate_kin
SRR25158416_k127_3450394_10	1312959.KI914646_gene909	1.713e-22	108.0	COG0586@1|root,COG0586@2|Bacteria,2ID8E@201174|Actinobacteria,1W9E9@1268|Micrococcaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158416_k127_3450394_0	1449353.JQMQ01000005_gene3258	0.0	1143.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,2NH60@228398|Streptacidiphilus	201174|Actinobacteria	L	Bacterial DNA topoisomeraes I ATP-binding domain	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158416_k127_3450394_9	1206733.BAGC01000063_gene3242	9.025e-53	194.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4FUKJ@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_3450394_1	1122611.KB903974_gene3172	8.275e-174	551.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4EG38@85012|Streptosporangiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR25158416_k127_3450394_5	1120949.KB903315_gene169	1.366e-97	321.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria,4DHT8@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_3450394_7	196162.Noca_3343	1.23e-71	244.0	COG0412@1|root,COG0412@2|Bacteria,2GTZG@201174|Actinobacteria,4DQFU@85009|Propionibacteriales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158416_k127_345764_2	1123320.KB889675_gene3980	1.095e-64	225.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria	201174|Actinobacteria	L	Glycosylase	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_345764_0	1504981.KO116_1495	6.974e-116	379.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,1RPWM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phenazine biosynthesis protein PhzF	pab	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158416_k127_345764_1	471857.Svir_37570	2.339e-93	316.0	COG0697@1|root,COG0697@2|Bacteria,2I9T9@201174|Actinobacteria,4E00C@85010|Pseudonocardiales	201174|Actinobacteria	EG	transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3465161_1	28444.JODQ01000011_gene3480	2.465e-29	123.0	COG1946@1|root,COG1946@2|Bacteria,2GMZB@201174|Actinobacteria,4EG4Z@85012|Streptosporangiales	201174|Actinobacteria	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158416_k127_3465161_2	272123.Anacy_2009	0.0004035	45.0	COG1357@1|root,COG5635@1|root,COG1357@2|Bacteria,COG5635@2|Bacteria,1G3AI@1117|Cyanobacteria,1HK7F@1161|Nostocales	1117|Cyanobacteria	T	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,Pentapeptide_3
SRR25158416_k127_3465161_0	485913.Krac_8093	2.577e-45	173.0	COG1673@1|root,COG1673@2|Bacteria,2G9JU@200795|Chloroflexi	200795|Chloroflexi	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SRR25158416_k127_346539_8	110319.CF8_1413	1.226e-161	514.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4DPKA@85009|Propionibacteriales	201174|Actinobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158416_k127_346539_4	710696.Intca_2454	9.041e-211	663.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4FFJ0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158416_k127_346539_5	1123320.KB889720_gene7488	8.251e-187	594.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158416_k127_346539_9	55952.BU52_19675	6.086e-153	491.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_346539_15	935839.JAGJ01000002_gene756	9.769e-92	314.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4F427@85017|Promicromonosporaceae	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158416_k127_346539_2	1206101.AZXC01000032_gene3400	2.808e-223	707.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158416_k127_346539_26	1227499.C493_04503	7.085e-19	97.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y34Q@28890|Euryarchaeota,23Z98@183963|Halobacteria	28890|Euryarchaeota	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_346539_23	1394178.AWOO02000022_gene7216	1.002e-35	139.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4EK8U@85012|Streptosporangiales	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158416_k127_346539_7	1123320.KB889571_gene5460	4.937e-163	520.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158416_k127_346539_18	1120950.KB892745_gene2866	4.017e-78	277.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4DP23@85009|Propionibacteriales	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
SRR25158416_k127_346539_17	1289387.AUKW01000008_gene4730	1.177e-81	281.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158416_k127_346539_3	656024.FsymDg_3853	4.446e-220	690.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4ERC5@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158416_k127_346539_11	1120950.KB892745_gene2870	9.636e-110	372.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4DPQZ@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158416_k127_346539_28	2045.KR76_10450	0.0001412	49.0	2DSZR@1|root,33I3C@2|Bacteria,2HYHK@201174|Actinobacteria,4DV1P@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	-
SRR25158416_k127_346539_27	1394178.AWOO02000022_gene7224	3.385e-09	61.0	COG5336@1|root,COG5336@2|Bacteria,2GQSS@201174|Actinobacteria,4EPZR@85012|Streptosporangiales	201174|Actinobacteria	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
SRR25158416_k127_346539_19	479435.Kfla_5052	3.924e-73	255.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4DPUV@85009|Propionibacteriales	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158416_k127_346539_25	196162.Noca_1758	1.197e-22	107.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4DS2C@85009|Propionibacteriales	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158416_k127_346539_20	585531.HMPREF0063_12229	1.68e-55	204.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4DQDT@85009|Propionibacteriales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158416_k127_346539_21	67257.JODR01000008_gene3444	6.984e-55	204.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
SRR25158416_k127_346539_0	58123.JOFJ01000009_gene927	1.031e-271	845.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4EG2U@85012|Streptosporangiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158416_k127_346539_13	1048339.KB913029_gene3397	7.45e-104	346.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4ERNM@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158416_k127_346539_1	2002.JOEQ01000004_gene2732	6.367e-239	751.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4EG3U@85012|Streptosporangiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158416_k127_346539_22	1157635.KB892001_gene2829	4.813e-43	163.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158416_k127_346539_24	1120950.KB892745_gene2881	2.48e-28	119.0	2E6YX@1|root,331I5@2|Bacteria,2IFIG@201174|Actinobacteria,4DRJC@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2550)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2550
SRR25158416_k127_346539_6	1120950.KB892745_gene2885	1.9e-175	559.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4DND6@85009|Propionibacteriales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158416_k127_346539_16	1206726.BAFV01000039_gene2696	2.266e-86	312.0	COG0671@1|root,COG0671@2|Bacteria,2IAXK@201174|Actinobacteria,4FWWC@85025|Nocardiaceae	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158416_k127_346539_10	1120950.KB892745_gene2887	4.657e-129	419.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4DQT0@85009|Propionibacteriales	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158416_k127_346539_12	446469.Sked_29920	1.537e-108	360.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158416_k127_346539_14	479432.Sros_1687	2.048e-94	314.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4EI49@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_3471960_1	1122138.AQUZ01000019_gene8133	7.429e-79	264.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4DP6U@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3471960_0	1122138.AQUZ01000019_gene8134	1.675e-193	611.0	COG5002@1|root,COG5002@2|Bacteria,2I5WN@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14982	ko02020,ko02024,map02020,map02024	M00521	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158416_k127_3530044_10	1134445.AJJM01000070_gene3494	3.222e-82	278.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158416_k127_3530044_5	479435.Kfla_4886	3.92e-182	573.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4DNFA@85009|Propionibacteriales	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158416_k127_3530044_11	1048339.KB913029_gene3460	1.166e-78	269.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4ESEU@85013|Frankiales	201174|Actinobacteria	E	Acetolactate synthase, small subunit	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158416_k127_3530044_1	1120950.KB892741_gene2671	4.471e-309	955.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4DNJX@85009|Propionibacteriales	201174|Actinobacteria	E	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158416_k127_3530044_18	1127134.NOCYR_1340	8.755e-29	123.0	COG2199@1|root,COG2199@2|Bacteria,2IACC@201174|Actinobacteria,4FVB3@85025|Nocardiaceae	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158416_k127_3530044_2	351607.Acel_0705	4.004e-293	906.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4ERXY@85013|Frankiales	201174|Actinobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158416_k127_3530044_19	1048339.KB913029_gene2864	2.762e-21	96.0	COG1977@1|root,COG1977@2|Bacteria,2GQM9@201174|Actinobacteria,4EWS6@85013|Frankiales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158416_k127_3530044_6	1380393.JHVP01000008_gene4533	7.133e-156	507.0	COG4409@1|root,COG4409@2|Bacteria,2I3YU@201174|Actinobacteria,4EXIE@85013|Frankiales	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3530044_16	1283283.ATXA01000005_gene2098	5.31e-41	155.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria,4EW3K@85013|Frankiales	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158416_k127_3530044_9	1120950.KB892741_gene2668	8.283e-112	369.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4DNYY@85009|Propionibacteriales	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	pdxB	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158416_k127_3530044_7	1048339.KB913029_gene3458	2.629e-120	402.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4ES6J@85013|Frankiales	201174|Actinobacteria	G	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158416_k127_3530044_21	1246448.ANAZ01000008_gene2380	1.291e-11	74.0	COG3595@1|root,COG3595@2|Bacteria,2I1WD@201174|Actinobacteria,4EPZD@85012|Streptosporangiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158416_k127_3530044_15	321327.CYA_2243	1.019e-41	160.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1H1NJ@1129|Synechococcus	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158416_k127_3530044_4	1123320.KB889714_gene8114	2.69e-226	710.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158416_k127_3530044_22	1463864.JOGO01000052_gene5012	0.0009785	50.0	2C7EP@1|root,2ZXNX@2|Bacteria,2IQ7Y@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3530044_3	1120950.KB892741_gene2662	8.87e-251	782.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4DN5B@85009|Propionibacteriales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158416_k127_3530044_17	2002.JOEQ01000012_gene5693	1.597e-33	134.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4EJUI@85012|Streptosporangiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158416_k127_3530044_12	479435.Kfla_5793	9.79e-71	248.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4DR1C@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	padR	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158416_k127_3530044_20	1032480.MLP_23110	4.177e-18	89.0	2EG6R@1|root,339YM@2|Bacteria,2GX31@201174|Actinobacteria,4DSMY@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR25158416_k127_3530044_8	35754.JNYJ01000043_gene4419	7.022e-116	383.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4D9RI@85008|Micromonosporales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158416_k127_3530044_13	649831.L083_1951	5.739e-48	180.0	2EGCD@1|root,33A46@2|Bacteria,2GIVH@201174|Actinobacteria,4DIYM@85008|Micromonosporales	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,Septum_form
SRR25158416_k127_3530044_0	1120949.KB903356_gene8769	3.505e-309	967.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4D8P7@85008|Micromonosporales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158416_k127_3530044_14	1120950.KB892741_gene2651	4.79e-47	177.0	COG0620@1|root,COG0620@2|Bacteria,2GMPS@201174|Actinobacteria,4DN0J@85009|Propionibacteriales	201174|Actinobacteria	E	Methionine synthase, vitamin-B12 independent	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
SRR25158416_k127_3531918_2	216594.MMAR_1373	4.925e-71	250.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,233GJ@1762|Mycobacteriaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,rve,rve_3
SRR25158416_k127_3531918_3	675635.Psed_1134	2.005e-07	59.0	290TI@1|root,2ZNFN@2|Bacteria,2HCTY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
SRR25158416_k127_3531918_0	35754.JNYJ01000006_gene5302	0.0	1559.0	COG1452@1|root,COG1452@2|Bacteria,2GNM6@201174|Actinobacteria,4DMCF@85008|Micromonosporales	201174|Actinobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
SRR25158416_k127_3531918_1	35754.JNYJ01000006_gene5303	7.85e-172	548.0	COG3408@1|root,COG3408@2|Bacteria,2IB24@201174|Actinobacteria,4D8TX@85008|Micromonosporales	201174|Actinobacteria	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158416_k127_3544204_1	525368.HMPREF0591_1696	2.225e-66	228.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,234RT@1762|Mycobacteriaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_29,HTH_32
SRR25158416_k127_3544204_4	2074.JNYD01000003_gene3918	3.873e-34	134.0	COG2329@1|root,COG2329@2|Bacteria,2H1KI@201174|Actinobacteria	201174|Actinobacteria	S	antibiotic biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_3544204_5	1206729.BAFZ01000051_gene5300	5.969e-27	114.0	COG0494@1|root,COG0494@2|Bacteria,2IKSQ@201174|Actinobacteria,4G3M4@85025|Nocardiaceae	201174|Actinobacteria	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,NYN_YacP
SRR25158416_k127_3544204_11	1150399.AQYK01000001_gene439	0.0001063	47.0	COG0316@1|root,COG0316@2|Bacteria,2GR0Z@201174|Actinobacteria,4FPYM@85023|Microbacteriaceae	201174|Actinobacteria	S	HesB YadR YfhF-family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR25158416_k127_3544204_3	525909.Afer_1128	3.83e-36	144.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158416_k127_3544204_2	211114.JOEF01000059_gene2714	4.818e-50	189.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4E7BJ@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_3544204_8	512565.AMIS_63990	3.149e-12	67.0	COG4941@1|root,COG4941@2|Bacteria	2|Bacteria	K	sigma factor activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3544204_7	272568.GDI2894	4.443e-15	81.0	2E3GE@1|root,32YF6@2|Bacteria,1N7MX@1224|Proteobacteria,2UFWC@28211|Alphaproteobacteria,2JXXY@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2188
SRR25158416_k127_3544204_0	1108045.GORHZ_205_00310	5.385e-179	572.0	COG1180@1|root,COG1180@2|Bacteria	2|Bacteria	C	glycyl-radical enzyme activating activity	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158416_k127_3544204_6	58123.JOFJ01000014_gene5039	1.638e-17	84.0	2EHDR@1|root,33B5K@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158416_k127_3544204_9	408672.NBCG_04035	4.174e-12	72.0	2BG65@1|root,32A2Y@2|Bacteria,2IRVF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3544204_10	1385519.N801_01750	3.034e-06	53.0	2BG65@1|root,32A2Y@2|Bacteria,2IRVF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3547019_7	1122138.AQUZ01000033_gene3627	1.461e-64	226.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4DNCY@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome b	qcrB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158416_k127_3547019_6	84531.JMTZ01000117_gene4266	3.761e-83	286.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1RS0P@1236|Gammaproteobacteria,1X4DJ@135614|Xanthomonadales	135614|Xanthomonadales	EG	Drug metabolite transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3547019_17	1449044.JMLE01000005_gene630	7.189e-08	63.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,1W7EG@1268|Micrococcaceae	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	catA	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
SRR25158416_k127_3547019_9	1120950.KB892707_gene4796	6.648e-54	192.0	2D9MJ@1|root,32TTI@2|Bacteria,2IFFM@201174|Actinobacteria,4DQZG@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the cytochrome c oxidase bacterial subunit CtaF family	ctaF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
SRR25158416_k127_3547019_2	110319.CF8_2767	1.241e-284	882.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4DPQI@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158416_k127_3547019_5	1122138.AQUZ01000102_gene40	6.455e-90	308.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4DNSR@85009|Propionibacteriales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158416_k127_3547019_3	469371.Tbis_1288	1.119e-156	509.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4DY3B@85010|Pseudonocardiales	201174|Actinobacteria	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158416_k127_3547019_12	196162.Noca_3143	6.742e-24	103.0	COG0425@1|root,COG0425@2|Bacteria,2GSF4@201174|Actinobacteria,4DSIR@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158416_k127_3547019_1	1121272.KB903290_gene4608	0.0	1238.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4D8NI@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158416_k127_3547019_16	1240349.ANGC01000033_gene2982	3.107e-14	74.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4FXZ9@85025|Nocardiaceae	201174|Actinobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3547019_14	1206735.BAGG01000069_gene3053	4.739e-22	102.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4FXZ9@85025|Nocardiaceae	201174|Actinobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3547019_15	469383.Cwoe_0609	9.987e-16	85.0	COG4803@1|root,COG4803@2|Bacteria,2IQV0@201174|Actinobacteria,4CTQN@84995|Rubrobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158416_k127_3547019_4	1240349.ANGC01000033_gene2989	2.191e-145	464.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria,4FXG4@85025|Nocardiaceae	201174|Actinobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4,GATase_6
SRR25158416_k127_3547019_10	269800.Tfu_2084	1.715e-29	128.0	2EGCD@1|root,33A46@2|Bacteria,2I14B@201174|Actinobacteria,4EKUH@85012|Streptosporangiales	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
SRR25158416_k127_3547019_13	43759.JNWK01000007_gene1883	7.993e-23	108.0	2DQB3@1|root,335R8@2|Bacteria,2GMQW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,DUF4352
SRR25158416_k127_3547019_11	105420.BBPO01000020_gene5617	8.377e-27	113.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,2NJRI@228398|Streptacidiphilus	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158416_k127_3547019_8	227882.SAV_1926	3.83e-62	218.0	COG4803@1|root,COG4803@2|Bacteria,2IIN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3547019_0	1095767.CAHD01000193_gene198	0.0	1285.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158416_k127_3551642_21	1121272.KB903253_gene6806	6.365e-92	304.0	COG0596@1|root,COG0596@2|Bacteria,2I97G@201174|Actinobacteria,4D922@85008|Micromonosporales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_3551642_41	266940.Krad_1727	1.355e-05	48.0	2DD4Z@1|root,2ZGIG@2|Bacteria,2HB2E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3551642_35	1380346.JNIH01000032_gene1161	1.99e-36	154.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
SRR25158416_k127_3551642_0	1120950.KB892740_gene2514	0.0	1217.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4DN2Z@85009|Propionibacteriales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158416_k127_3551642_1	351607.Acel_0005	0.0	1018.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4ES0Z@85013|Frankiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158416_k127_3551642_32	1122138.AQUZ01000007_gene3147	1.67e-43	169.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4DR8Q@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158416_k127_3551642_7	1048339.KB913029_gene1671	2.572e-154	508.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4ES7H@85013|Frankiales	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158416_k127_3551642_11	1120934.KB894421_gene2515	1.206e-143	467.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4DYVC@85010|Pseudonocardiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158416_k127_3551642_10	1120950.KB892740_gene2519	9.189e-148	477.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4DN43@85009|Propionibacteriales	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158416_k127_3551642_5	1122138.AQUZ01000007_gene3151	1.403e-197	628.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4DMZ1@85009|Propionibacteriales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158416_k127_3551642_39	1292020.H483_0100205	3.301e-14	73.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158416_k127_3551642_37	471852.Tcur_4984	2.036e-21	100.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4EKWP@85012|Streptosporangiales	201174|Actinobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0008150,GO:0040007	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158416_k127_3551642_36	397278.JOJN01000003_gene1750	3.657e-29	118.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4DSGI@85009|Propionibacteriales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158416_k127_3551642_19	1120950.KB892740_gene2522	6.867e-102	340.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4DNB3@85009|Propionibacteriales	201174|Actinobacteria	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158416_k127_3551642_25	1463934.JOCF01000011_gene4453	3.214e-65	231.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria	201174|Actinobacteria	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR25158416_k127_3551642_27	1394178.AWOO02000011_gene3852	8.088e-64	226.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4EIK1@85012|Streptosporangiales	201174|Actinobacteria	M	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158416_k127_3551642_14	1463856.JOHY01000002_gene1375	1.409e-127	422.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria	201174|Actinobacteria	D	chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158416_k127_3551642_17	1122609.AUGT01000019_gene329	1.626e-117	389.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4DNPD@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158416_k127_3551642_22	469371.Tbis_3580	3.688e-83	285.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria,4DXW4@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_3551642_9	1120950.KB892740_gene2531	1.509e-149	488.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4DN51@85009|Propionibacteriales	201174|Actinobacteria	M	Ami_3	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
SRR25158416_k127_3551642_33	1996.JOFO01000007_gene4519	1.007e-41	156.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4EJRR@85012|Streptosporangiales	201174|Actinobacteria	O	Thioredoxin-like	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158416_k127_3551642_8	1380370.JIBA01000010_gene2461	1.457e-152	489.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4FEXJ@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158416_k127_3551642_40	469371.Tbis_3577	7.964e-09	66.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_3551642_26	1463934.JOCF01000011_gene4445	1.892e-64	226.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3551642_18	1120950.KB892740_gene2536	6.659e-111	377.0	COG0515@1|root,COG0515@2|Bacteria,2GM4A@201174|Actinobacteria,4DN49@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158416_k127_3551642_12	1298863.AUEP01000006_gene3472	4.889e-133	449.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4DNJI@85009|Propionibacteriales	201174|Actinobacteria	KLT	MviN-like protein	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158416_k127_3551642_30	1123322.KB904669_gene3617	5.207e-48	195.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3551642_28	446462.Amir_7080	8.931e-53	196.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,4EE5K@85010|Pseudonocardiales	201174|Actinobacteria	L	NUDIX domain	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158416_k127_3551642_3	1120950.KB892740_gene2539	5.588e-220	694.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4DMZV@85009|Propionibacteriales	201174|Actinobacteria	J	Probable RNA and SrmB- binding site of polymerase A	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158416_k127_3551642_16	1120950.KB892740_gene2540	4.843e-123	408.0	COG2270@1|root,COG2270@2|Bacteria,2GK5A@201174|Actinobacteria,4DQ23@85009|Propionibacteriales	201174|Actinobacteria	S	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_3551642_23	105422.BBPM01000002_gene5015	6.434e-83	279.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria,2NFBV@228398|Streptacidiphilus	201174|Actinobacteria	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR25158416_k127_3551642_38	469371.Tbis_0976	2.763e-21	97.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria,4E446@85010|Pseudonocardiales	201174|Actinobacteria	K	Protein of unknown function (DUF742)	cvnC6	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR25158416_k127_3551642_34	105422.BBPM01000002_gene5013	2.787e-40	154.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria,2NI6B@228398|Streptacidiphilus	201174|Actinobacteria	S	Roadblock/LC7 domain	cvnB6	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR25158416_k127_3551642_20	67373.JOBF01000019_gene5737	8.434e-100	359.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,2GK6E@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	cvnA6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158416_k127_3551642_4	479435.Kfla_7020	3.404e-214	674.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4DNQF@85009|Propionibacteriales	201174|Actinobacteria	I	Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158416_k127_3551642_24	1394178.AWOO02000091_gene1052	3.065e-71	253.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,4EIBC@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158416_k127_3551642_6	1120950.KB892740_gene2544	3.498e-179	591.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DMYZ@85009|Propionibacteriales	201174|Actinobacteria	M	Transglycosylase	pbp5	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158416_k127_3551642_13	1048339.KB913029_gene1636	5.024e-129	426.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,4ES94@85013|Frankiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158416_k127_3551642_15	1120950.KB892740_gene2546	2.427e-127	418.0	COG5542@1|root,COG5542@2|Bacteria,2HZNP@201174|Actinobacteria,4DTDM@85009|Propionibacteriales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158416_k127_3551642_2	994479.GL877879_gene4174	4.491e-267	839.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria,4DXYH@85010|Pseudonocardiales	201174|Actinobacteria	Q	Copper amine oxidase, enzyme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRR25158416_k127_3551642_29	263358.VAB18032_14175	5.575e-49	187.0	2E86Z@1|root,332K7@2|Bacteria,2ICI7@201174|Actinobacteria,4DC0H@85008|Micromonosporales	201174|Actinobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
SRR25158416_k127_3551642_31	391037.Sare_1731	9.65e-45	165.0	COG0531@1|root,COG0531@2|Bacteria,2GJ1D@201174|Actinobacteria,4DB22@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158416_k127_3561485_3	1944.JOAZ01000003_gene5261	8.004e-11	63.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,41BRB@629295|Streptomyces griseus group	201174|Actinobacteria	I	Coenzyme A transferase	scoB	-	2.8.3.5	ko:K01027,ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158416_k127_3561485_1	1122611.KB903971_gene2679	1.782e-121	405.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4EHRW@85012|Streptosporangiales	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158416_k127_3561485_0	446466.Cfla_1942	1.206e-164	526.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4F0MD@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158416_k127_3561485_2	35754.JNYJ01000012_gene979	3.355e-74	250.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4D98B@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158416_k127_3563794_4	1416759.AYMR01000008_gene2712	0.0001028	47.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4FP0M@85023|Microbacteriaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
SRR25158416_k127_3563794_2	1313172.YM304_31580	2.858e-44	164.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_3563794_1	1313172.YM304_31570	7.395e-55	199.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	gstF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1,GST_C,GST_N_3
SRR25158416_k127_3563794_3	1380393.JHVP01000007_gene4325	8.066e-19	91.0	2EPJR@1|root,33H6B@2|Bacteria,2GXK1@201174|Actinobacteria,4EWWU@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3563794_0	446470.Snas_2986	6.258e-59	210.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158416_k127_3571208_3	1283283.ATXA01000015_gene77	2.244e-13	70.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4EREZ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_3571208_1	1463825.JNXC01000004_gene4190	8.92e-38	149.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4E11A@85010|Pseudonocardiales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
SRR25158416_k127_3571208_2	345341.KUTG_01815	1.958e-23	106.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4E11A@85010|Pseudonocardiales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
SRR25158416_k127_3571208_0	313589.JNB_18563	2.384e-67	240.0	COG2227@1|root,COG2227@2|Bacteria,2IPID@201174|Actinobacteria,4FIVA@85021|Intrasporangiaceae	201174|Actinobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158416_k127_3598542_3	338969.Rfer_4133	8.016e-11	66.0	COG1846@1|root,COG1846@2|Bacteria,1RJEE@1224|Proteobacteria,2VSK5@28216|Betaproteobacteria,4AEZ0@80864|Comamonadaceae	28216|Betaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158416_k127_3598542_0	263358.VAB18032_11730	5.002e-86	317.0	COG2866@1|root,COG2866@2|Bacteria,2GJ8D@201174|Actinobacteria,4DIG8@85008|Micromonosporales	201174|Actinobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_3598542_1	1380390.JIAT01000011_gene2535	2.473e-50	193.0	COG3055@1|root,COG3055@2|Bacteria,2HPP7@201174|Actinobacteria,4CR1T@84995|Rubrobacteria	84995|Rubrobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3598542_2	309801.trd_1922	9.252e-31	134.0	COG0028@1|root,COG3055@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,2GBSZ@200795|Chloroflexi,27ZA5@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_362480_2	469383.Cwoe_2414	2.717e-74	254.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria,4CSKA@84995|Rubrobacteria	84995|Rubrobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
SRR25158416_k127_362480_3	1054860.KB913030_gene481	1.404e-31	128.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3
SRR25158416_k127_362480_0	469383.Cwoe_3826	2.32e-147	483.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRR25158416_k127_362480_1	266117.Rxyl_1756	8.81e-97	320.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4CQIA@84995|Rubrobacteria	84995|Rubrobacteria	S	phenylacetic acid catabolic	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158416_k127_3645817_1	287986.DV20_16540	1.916e-78	265.0	COG4147@1|root,COG4147@2|Bacteria,2GJ56@201174|Actinobacteria,4DYB4@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158416_k127_3645817_0	479431.Namu_4720	4.794e-239	751.0	COG3243@1|root,COG3243@2|Bacteria,2GNYP@201174|Actinobacteria,4ETZS@85013|Frankiales	201174|Actinobacteria	I	PFAM Poly-beta-hydroxybutyrate polymerase domain protein	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
SRR25158416_k127_3645817_2	1120948.KB903219_gene657	3.099e-30	123.0	COG1396@1|root,COG1396@2|Bacteria,2GPQW@201174|Actinobacteria,4EC3K@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158416_k127_3679650_2	1297570.MESS4_670018	1.145e-94	336.0	COG5361@1|root,COG5361@2|Bacteria,1NX2A@1224|Proteobacteria,2TQNZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158416_k127_3679650_0	1298864.AUEQ01000023_gene1398	0.0	1277.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	atsD	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158416_k127_3679650_4	136273.GY22_06745	5.493e-27	124.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,1W8PC@1268|Micrococcaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158416_k127_3679650_1	1449069.JMLO01000034_gene123	6.928e-176	567.0	COG3119@1|root,COG3119@2|Bacteria,2I9IZ@201174|Actinobacteria,4G8Q1@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158416_k127_3679650_3	1229780.BN381_40041	3.933e-48	179.0	2CK3K@1|root,32SBH@2|Bacteria,2IQJH@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Ion	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158416_k127_3679650_5	1033730.CAHG01000016_gene541	1.102e-05	51.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Glyco_hydro_2,Virul_fac_BrkB
SRR25158416_k127_3680590_16	68570.DC74_5946	1.188e-79	269.0	COG0454@1|root,COG0456@2|Bacteria,2IAC7@201174|Actinobacteria	201174|Actinobacteria	K	Aminoglycoside 2'-N-acetyltransferase	aac	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_9
SRR25158416_k127_3680590_1	1095767.CAHD01000213_gene627	1.394e-237	748.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158416_k127_3680590_3	1150864.MILUP08_44832	1.137e-201	654.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DGT8@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 1	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158416_k127_3680590_12	1214101.BN159_1461	1.072e-122	402.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	attS	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
SRR25158416_k127_3680590_30	501479.ACNW01000104_gene525	4.987e-20	103.0	COG1652@1|root,COG1652@2|Bacteria,1RCB6@1224|Proteobacteria,2U5WG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Gmad2,LysM
SRR25158416_k127_3680590_20	443255.SCLAV_4943	3.542e-51	188.0	COG1162@1|root,COG1162@2|Bacteria,2IMZI@201174|Actinobacteria	201174|Actinobacteria	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
SRR25158416_k127_3680590_31	1313172.YM304_01380	4.694e-16	87.0	2EPZ4@1|root,33HJQ@2|Bacteria,2GYV7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3680590_29	356851.JOAN01000012_gene5114	2.026e-24	106.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4DFT4@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158416_k127_3680590_25	1211815.CBYP010000041_gene2521	4.774e-36	147.0	COG3764@1|root,COG3764@2|Bacteria,2II8M@201174|Actinobacteria	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158416_k127_3680590_23	1146883.BLASA_3901	1.98e-44	173.0	2DPJ9@1|root,332BI@2|Bacteria,2IGJC@201174|Actinobacteria,4EVSY@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158416_k127_3680590_0	1380386.JIAW01000004_gene361	1.206e-244	780.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,2371U@1762|Mycobacteriaceae	201174|Actinobacteria	G	PTS system fructose IIA component	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N,PTS-HPr
SRR25158416_k127_3680590_18	1123023.JIAI01000002_gene4895	1.696e-76	267.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4E2P5@85010|Pseudonocardiales	201174|Actinobacteria	S	Dihydroxyacetone kinase	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158416_k127_3680590_6	1160137.KB907307_gene4168	1.483e-173	548.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4FYJA@85025|Nocardiaceae	201174|Actinobacteria	G	Dak1 domain	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1
SRR25158416_k127_3680590_19	500153.JOEK01000009_gene4739	7.916e-67	242.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158416_k127_3680590_28	1394178.AWOO02000075_gene1979	7.063e-27	115.0	COG2261@1|root,COG2261@2|Bacteria,2IQGD@201174|Actinobacteria,4EKJC@85012|Streptosporangiales	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158416_k127_3680590_9	103733.JNYO01000012_gene2639	5.109e-154	507.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DXA1@85010|Pseudonocardiales	201174|Actinobacteria	S	Pirin C-terminal cupin domain	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158416_k127_3680590_27	644283.Micau_4183	1.256e-28	126.0	COG3409@1|root,COG3409@2|Bacteria,2HUZI@201174|Actinobacteria,4DGE9@85008|Micromonosporales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3680590_2	390989.JOEG01000025_gene33	1.463e-235	740.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4DABQ@85008|Micromonosporales	201174|Actinobacteria	E	GMC oxidoreductase	choA	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158416_k127_3680590_15	196162.Noca_0473	3.042e-93	311.0	2DKWQ@1|root,30MQE@2|Bacteria,2I3CS@201174|Actinobacteria,4DWYQ@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
SRR25158416_k127_3680590_13	1120950.KB892773_gene1084	5.35e-96	331.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4DN5P@85009|Propionibacteriales	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
SRR25158416_k127_3680590_21	1380390.JIAT01000009_gene1008	1.24e-47	177.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CQF3@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158416_k127_3680590_33	479433.Caci_8846	6.529e-15	87.0	2EV1Z@1|root,33NH1@2|Bacteria,2GZIA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3680590_24	1463895.JODA01000003_gene698	7.321e-38	145.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158416_k127_3680590_26	1380347.JNII01000007_gene137	7.845e-29	123.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria,4EWMM@85013|Frankiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3680590_32	1146883.BLASA_4759	1.015e-15	81.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria,4EWMM@85013|Frankiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3680590_10	1160718.SU9_14041	5.134e-154	494.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria	201174|Actinobacteria	E	May catalyze the transamination reaction in phenylalanine biosynthesis	pat	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158416_k127_3680590_17	58123.JOFJ01000001_gene3242	9.976e-77	274.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria,4EIG7@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,TPR_12,TPR_16
SRR25158416_k127_3680590_14	479435.Kfla_6869	1.141e-95	323.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DUT2@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3680590_4	110319.CF8_3600	1.124e-182	580.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4DNN1@85009|Propionibacteriales	201174|Actinobacteria	C	dehydrogenase, E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158416_k127_3680590_7	33876.JNXY01000025_gene5335	5.221e-161	526.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4DA2N@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158416_k127_3680590_8	367299.JOEE01000002_gene2389	1.076e-155	507.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,4FFEF@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158416_k127_3680590_5	479435.Kfla_6850	1.001e-180	572.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4DP0X@85009|Propionibacteriales	201174|Actinobacteria	I	Thiolase, C-terminal domain	paaJ	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_3680590_22	670292.JH26_27120	6.897e-46	173.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,2U5QW@28211|Alphaproteobacteria,1JV7J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Phenylacetic acid degradation protein PaaD	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SRR25158416_k127_3680590_11	1121033.AUCF01000014_gene1279	1.001e-131	436.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TSGF@28211|Alphaproteobacteria,2JPV5@204441|Rhodospirillales	204441|Rhodospirillales	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158416_k127_3680609_13	1157943.KB892705_gene2259	2.138e-11	69.0	2BNXG@1|root,32HMG@2|Bacteria,2H5CQ@201174|Actinobacteria,23DT7@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3680609_15	1146883.BLASA_4015	6.45e-06	52.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4ETR1@85013|Frankiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR25158416_k127_3680609_7	1429046.RR21198_1602	1.01e-94	317.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4G04S@85025|Nocardiaceae	201174|Actinobacteria	IQ	NAD dependent epimerase/dehydratase family	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3680609_12	526225.Gobs_2422	3.187e-14	78.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4EUUM@85013|Frankiales	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_3680609_1	656024.FsymDg_3822	5.085e-182	577.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4ES7F@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_3680609_2	405948.SACE_2374	5.201e-168	557.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4E0VQ@85010|Pseudonocardiales	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_3680609_9	118163.Ple7327_0161	7.119e-29	115.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3VIAJ@52604|Pleurocapsales	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00130,ko:K00135,ko:K00146,ko:K22187	ko00040,ko00250,ko00260,ko00310,ko00350,ko00360,ko00643,ko00650,ko00760,ko01100,ko01120,map00040,map00250,map00260,map00310,map00350,map00360,map00643,map00650,map00760,map01100,map01120	M00027,M00555	R00713,R00714,R02401,R02536,R02565,R02566,R11768	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_3680609_3	118163.Ple7327_0161	6.352e-153	513.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3VIAJ@52604|Pleurocapsales	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00130,ko:K00135,ko:K00146,ko:K22187	ko00040,ko00250,ko00260,ko00310,ko00350,ko00360,ko00643,ko00650,ko00760,ko01100,ko01120,map00040,map00250,map00260,map00310,map00350,map00360,map00643,map00650,map00760,map01100,map01120	M00027,M00555	R00713,R00714,R02401,R02536,R02565,R02566,R11768	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_3680609_11	1206731.BAGB01000041_gene8435	1.388e-17	95.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FTXB@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158416_k127_3680609_4	1137269.AZWL01000006_gene6564	3.919e-125	407.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158416_k127_3680609_14	47763.JNZA01000028_gene6158	9.927e-11	67.0	COG0025@1|root,COG0025@2|Bacteria,2I2S7@201174|Actinobacteria	201174|Actinobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158416_k127_3680609_0	656024.FsymDg_3800	3.207e-314	973.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158416_k127_3680609_10	1120936.KB907213_gene4865	1.09e-22	106.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4EGFY@85012|Streptosporangiales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158416_k127_3680609_5	561175.KB894093_gene4312	1.45e-122	399.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4EGFY@85012|Streptosporangiales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158416_k127_3680609_8	1120948.KB903229_gene5045	5.946e-51	183.0	COG3609@1|root,COG3609@2|Bacteria,2INEB@201174|Actinobacteria,4EB94@85010|Pseudonocardiales	201174|Actinobacteria	K	addiction module antidote protein, CC2985 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3680609_6	1123024.AUII01000004_gene1471	2.774e-96	329.0	COG3509@1|root,COG3509@2|Bacteria,2GMTA@201174|Actinobacteria,4DZE7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	phaZ1	-	3.1.1.72	ko:K05972	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Esterase_phd,RicinB_lectin_2,Ricin_B_lectin
SRR25158416_k127_3681110_12	1120950.KB892764_gene5605	4.502e-39	153.0	2E4C6@1|root,32Z7Q@2|Bacteria,2GRH1@201174|Actinobacteria,4DRZF@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3681110_15	1120950.KB892764_gene5606	6.226e-29	120.0	COG3311@1|root,COG3311@2|Bacteria,2GR98@201174|Actinobacteria,4DS1Q@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_3681110_19	471853.Bcav_1257	4.244e-09	64.0	COG1261@1|root,COG1261@2|Bacteria,2GR8T@201174|Actinobacteria	201174|Actinobacteria	NO	PFAM SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
SRR25158416_k127_3681110_4	1120950.KB892764_gene5608	1.609e-135	449.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4DQ9Q@85009|Propionibacteriales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158416_k127_3681110_3	1122138.AQUZ01000032_gene7214	5.302e-153	496.0	arCOG02771@1|root,2Z8A4@2|Bacteria,2GNG0@201174|Actinobacteria,4DN40@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3681110_18	479432.Sros_2595	6.158e-17	86.0	COG1622@1|root,COG1622@2|Bacteria,2GS05@201174|Actinobacteria,4EKJK@85012|Streptosporangiales	201174|Actinobacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158416_k127_3681110_1	1120950.KB892764_gene5614	6.949e-178	570.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4DN7F@85009|Propionibacteriales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	tgs3	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158416_k127_3681110_6	235985.BBPN01000026_gene1441	4.542e-93	316.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,2NGGN@228398|Streptacidiphilus	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158416_k127_3681110_13	711393.AYRX01000018_gene3199	1.704e-38	151.0	2DRWJ@1|root,32URV@2|Bacteria,2IFAY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3681110_0	367299.JOEE01000003_gene2926	8.279e-263	818.0	COG1012@1|root,COG1012@2|Bacteria,2GJZE@201174|Actinobacteria,4FFQI@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dehydrogenase	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158416_k127_3681110_7	397278.JOJN01000006_gene1015	1.297e-89	301.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4DNEI@85009|Propionibacteriales	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
SRR25158416_k127_3681110_8	479432.Sros_8416	6.36e-88	298.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4EHBC@85012|Streptosporangiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_3681110_16	469371.Tbis_3013	7.441e-19	96.0	COG5662@1|root,COG5662@2|Bacteria,2GKPI@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_3681110_10	1120950.KB892823_gene489	8.729e-47	187.0	COG3026@1|root,COG3026@2|Bacteria,2IRR9@201174|Actinobacteria,4DSGE@85009|Propionibacteriales	201174|Actinobacteria	T	antisigma factor binding	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB
SRR25158416_k127_3681110_5	590998.Celf_2880	6.027e-96	329.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4F0ZZ@85016|Cellulomonadaceae	201174|Actinobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	sprI	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158416_k127_3681110_17	1122138.AQUZ01000003_gene572	2.584e-18	90.0	COG1826@1|root,COG1826@2|Bacteria,2IR0U@201174|Actinobacteria,4DRKC@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0008150,GO:0040007	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158416_k127_3681110_2	1123322.KB904635_gene2478	5.315e-166	529.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158416_k127_3681110_11	222534.KB893670_gene3715	3.158e-40	154.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator (MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158416_k127_3681110_9	356851.JOAN01000031_gene5300	4.134e-66	237.0	COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria,4D9JP@85008|Micromonosporales	201174|Actinobacteria	P	cobalt transport	ykoC	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158416_k127_3681110_14	1120950.KB892707_gene4945	4.145e-33	130.0	COG1123@1|root,COG4172@2|Bacteria,2H2BQ@201174|Actinobacteria,4DWHF@85009|Propionibacteriales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	ykoD	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158416_k127_3686829_0	471853.Bcav_4133	1.245e-281	883.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158416_k127_3686829_1	1713.JOFV01000021_gene1288	3.263e-28	119.0	COG0599@1|root,COG0599@2|Bacteria,2GTHM@201174|Actinobacteria	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158416_k127_3691321_41	1120960.ATXG01000017_gene1398	2.03e-06	56.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4FQ2J@85023|Microbacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_3691321_23	390989.JOEG01000020_gene2731	1.787e-54	199.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria,4DCSH@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
SRR25158416_k127_3691321_38	443255.SCLAV_p1287	2.368e-24	115.0	2ASCZ@1|root,31HSE@2|Bacteria,2IEI1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3691321_37	1380354.JIAN01000006_gene804	2.845e-25	110.0	2E76N@1|root,331QJ@2|Bacteria,2ITA1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3691321_2	479435.Kfla_1758	1.503e-188	601.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DP2B@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158416_k127_3691321_7	561175.KB894095_gene2286	2.501e-163	522.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4EGV1@85012|Streptosporangiales	201174|Actinobacteria	E	Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158416_k127_3691321_21	1123320.KB889719_gene7350	1.616e-61	215.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
SRR25158416_k127_3691321_20	1048339.KB913029_gene33	1.722e-70	251.0	COG0454@1|root,COG0456@2|Bacteria,2H5WU@201174|Actinobacteria,4ET2R@85013|Frankiales	201174|Actinobacteria	K	FR47-like protein	-	-	2.3.1.1	ko:K22476	ko00220,ko01210,ko01230,map00220,map01210,map01230	-	R00259	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,FR47
SRR25158416_k127_3691321_15	1120950.KB892823_gene520	1.023e-115	395.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4DN8K@85009|Propionibacteriales	201174|Actinobacteria	V	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158416_k127_3691321_14	1033730.CAHG01000012_gene2122	4.145e-119	392.0	COG2120@1|root,COG2120@2|Bacteria,2GKUM@201174|Actinobacteria,4DN6S@85009|Propionibacteriales	201174|Actinobacteria	S	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway	mshB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	3.5.1.103	ko:K15525	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158416_k127_3691321_5	1122611.KB903994_gene7383	2.193e-172	548.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EGK6@85012|Streptosporangiales	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158416_k127_3691321_8	1123320.KB889719_gene7334	7.611e-155	496.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158416_k127_3691321_18	1048339.KB913029_gene1646	1.693e-104	351.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4EUHI@85013|Frankiales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158416_k127_3691321_13	446462.Amir_0677	1.585e-125	410.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DZ5D@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158416_k127_3691321_3	1385518.N798_08935	5.886e-188	614.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4FE56@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptide ABC transporter substrate-binding protein	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158416_k127_3691321_31	1048339.KB913029_gene73	1.422e-30	123.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4ET9E@85013|Frankiales	201174|Actinobacteria	H	PFAM transcriptional coactivator pterin dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158416_k127_3691321_40	1151122.AQYD01000005_gene3241	1.424e-11	68.0	COG4249@1|root,COG4249@2|Bacteria,2I7QS@201174|Actinobacteria	201174|Actinobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
SRR25158416_k127_3691321_28	408672.NBCG_00948	6.69e-33	133.0	COG3945@1|root,COG3945@2|Bacteria,2I3V5@201174|Actinobacteria,4DV25@85009|Propionibacteriales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_3691321_29	1146883.BLASA_2933	2.62e-31	124.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4ETAA@85013|Frankiales	201174|Actinobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158416_k127_3691321_4	543632.JOJL01000009_gene6043	9.372e-186	592.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4DCD5@85008|Micromonosporales	201174|Actinobacteria	G	Alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
SRR25158416_k127_3691321_16	543632.JOJL01000009_gene6043	2.961e-108	355.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4DCD5@85008|Micromonosporales	201174|Actinobacteria	G	Alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
SRR25158416_k127_3691321_22	1120950.KB892707_gene4812	2.37e-59	219.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4DQU1@85009|Propionibacteriales	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158416_k127_3691321_30	710686.Mycsm_06300	1.148e-30	124.0	2BARS@1|root,3246W@2|Bacteria,2IM0H@201174|Actinobacteria,23ABR@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3691321_11	1449353.JQMQ01000005_gene1032	3.459e-133	435.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,2NGIJ@228398|Streptacidiphilus	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006183,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030808,GO:0031323,GO:0031326,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046777,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051704,GO:0055086,GO:0062012,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158416_k127_3691321_10	390989.JOEG01000006_gene802	1.199e-149	486.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4DCGK@85008|Micromonosporales	201174|Actinobacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_3691321_24	457429.ABJI02000656_gene6	1.258e-46	170.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_3691321_9	1150864.MILUP08_41810	3.817e-153	503.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4D91E@85008|Micromonosporales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
SRR25158416_k127_3691321_19	1122182.KB903836_gene4788	2.452e-89	301.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4DB3Q@85008|Micromonosporales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3691321_27	290399.Arth_2134	5.41e-41	157.0	COG3467@1|root,COG3467@2|Bacteria,2IP5U@201174|Actinobacteria,1W9TE@1268|Micrococcaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR25158416_k127_3691321_39	29306.JOBE01000030_gene921	1.432e-13	78.0	COG1366@1|root,COG1366@2|Bacteria,2IHX1@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS,STAS_2
SRR25158416_k127_3691321_12	512565.AMIS_60050	8.167e-127	428.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria,4DFGC@85008|Micromonosporales	201174|Actinobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158416_k127_3691321_34	2045.KR76_06580	1.611e-27	128.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4DPEX@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158416_k127_3691321_6	469383.Cwoe_1088	1.645e-169	537.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158416_k127_3691321_0	330214.NIDE1067	5.165e-211	679.0	2DBJW@1|root,2Z9P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3691321_26	882083.SacmaDRAFT_2314	3.745e-43	160.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,4E6B1@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_3691321_25	526225.Gobs_1475	4.729e-46	169.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4EVRM@85013|Frankiales	201174|Actinobacteria	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158416_k127_3691321_33	526225.Gobs_1475	6.09e-28	119.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4EVRM@85013|Frankiales	201174|Actinobacteria	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158416_k127_3691321_32	1123024.AUII01000013_gene416	1.475e-30	128.0	2EH65@1|root,33AY1@2|Bacteria,2I34E@201174|Actinobacteria,4EE7S@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876
SRR25158416_k127_3691321_1	1206737.BAGF01000084_gene5315	1.503e-200	629.0	COG1180@1|root,COG1180@2|Bacteria	2|Bacteria	C	glycyl-radical enzyme activating activity	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158416_k127_3691321_17	1122182.KB903837_gene3780	3.48e-107	356.0	COG0697@1|root,COG0697@2|Bacteria,2I91Y@201174|Actinobacteria,4DF2R@85008|Micromonosporales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158416_k127_3691321_35	1121952.ATXT01000017_gene949	5.115e-26	109.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_3693352_1	219305.MCAG_04125	6.714e-05	55.0	COG1276@1|root,COG1276@2|Bacteria,2I54P@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein D	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158416_k127_3694312_7	512565.AMIS_15810	1.154e-29	123.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4DBPM@85008|Micromonosporales	201174|Actinobacteria	E	Receptor family ligand binding region	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158416_k127_3694312_6	367299.JOEE01000005_gene3569	8.357e-34	147.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4FG5U@85021|Intrasporangiaceae	201174|Actinobacteria	E	branched-chain amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158416_k127_3694312_5	196162.Noca_3018	1.092e-80	277.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4DNSI@85009|Propionibacteriales	201174|Actinobacteria	T	ANTAR	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158416_k127_3694312_2	367299.JOEE01000005_gene3518	1.392e-205	649.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4FEJM@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the formation of phosphoenolpyruvate from pyruvate	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158416_k127_3694312_1	196162.Noca_3021	3.146e-246	771.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4DNI1@85009|Propionibacteriales	201174|Actinobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
SRR25158416_k127_3694312_0	996637.SGM_5655	0.0	2299.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria	201174|Actinobacteria	E	Glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158416_k127_3694312_4	1157634.KB912977_gene9	1.852e-88	297.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158416_k127_3694312_3	67257.JODR01000007_gene3803	7.785e-111	362.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158416_k127_3714124_0	1120950.KB892796_gene2279	1.241e-100	331.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DNJE@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158416_k127_3714124_3	1385520.N802_07670	3.617e-35	140.0	2EA9M@1|root,334E1@2|Bacteria,2I49S@201174|Actinobacteria	201174|Actinobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158416_k127_3714124_2	1463887.KL590085_gene537	2.098e-48	198.0	COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,VCBS
SRR25158416_k127_3714124_5	926550.CLDAP_23490	0.0008744	53.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158416_k127_3714124_1	1394178.AWOO02000013_gene7944	4.881e-56	204.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158416_k127_3721689_2	1463821.JOGR01000002_gene614	3.424e-55	203.0	COG0596@1|root,COG0596@2|Bacteria,2GJ4I@201174|Actinobacteria,4F00U@85014|Glycomycetales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_3721689_3	1035308.AQYY01000001_gene2437	2.051e-07	57.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,260R0@186807|Peptococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SRR25158416_k127_3721689_0	471854.Dfer_1353	1.566e-75	259.0	COG0262@1|root,COG0262@2|Bacteria,4NPV0@976|Bacteroidetes,47QWD@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_3721689_1	479432.Sros_4136	3.147e-58	209.0	COG0596@1|root,COG0596@2|Bacteria,2I9PQ@201174|Actinobacteria,4EHNW@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158416_k127_3726837_3	1157943.KB892705_gene2248	3.507e-65	225.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,234WQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158416_k127_3726837_2	1157943.KB892705_gene2250	7.635e-181	575.0	COG3243@1|root,COG3243@2|Bacteria,2GM1C@201174|Actinobacteria,23CJ7@1762|Mycobacteriaceae	201174|Actinobacteria	I	Protein of unknown function (DUF3141)	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158416_k127_3726837_4	1120797.KB908261_gene156	2.303e-55	205.0	2BKX7@1|root,32FDQ@2|Bacteria,2H3D3@201174|Actinobacteria,23C81@1762|Mycobacteriaceae	201174|Actinobacteria	S	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
SRR25158416_k127_3726837_1	1157943.KB892705_gene2252	1.587e-183	582.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,23590@1762|Mycobacteriaceae	201174|Actinobacteria	C	alcohol dehydrogenase	adh	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_3726837_0	1157943.KB892705_gene2253	3.413e-220	689.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,234U4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvB1_2	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158416_k127_3728420_6	101510.RHA1_ro02601	4.491e-09	63.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4FX4Z@85025|Nocardiaceae	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158416_k127_3728420_2	253839.SSNG_06068	3.108e-52	190.0	COG4226@1|root,COG4226@2|Bacteria,2IKXB@201174|Actinobacteria	201174|Actinobacteria	S	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	HicB
SRR25158416_k127_3728420_5	1068980.ARVW01000001_gene8085	3.294e-26	115.0	29YXX@1|root,30KUP@2|Bacteria,2GYS9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3728420_3	1246995.AFR_26500	9.031e-38	151.0	COG3832@1|root,COG3832@2|Bacteria,2IHQF@201174|Actinobacteria,4DFBR@85008|Micromonosporales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_3728420_0	1122611.KB903961_gene4422	4.12e-98	327.0	COG2273@1|root,COG2273@2|Bacteria,2GTJC@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SRR25158416_k127_3728420_4	469383.Cwoe_4791	2.542e-37	146.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria	201174|Actinobacteria	I	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158416_k127_3728420_7	1120950.KB892750_gene6910	2.88e-06	49.0	COG0596@1|root,COG0596@2|Bacteria,2I3M5@201174|Actinobacteria,4DNJF@85009|Propionibacteriales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_3728420_1	1352941.M877_02830	1.999e-72	245.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3729786_27	1121952.ATXT01000017_gene949	1.741e-06	53.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_3729786_13	479435.Kfla_0264	2.922e-100	336.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4DNDU@85009|Propionibacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158416_k127_3729786_14	1121946.AUAX01000011_gene4128	2.059e-95	317.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4DAFX@85008|Micromonosporales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158416_k127_3729786_6	1121926.AXWO01000001_gene3377	5.955e-144	464.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4F021@85014|Glycomycetales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SRR25158416_k127_3729786_8	1068978.AMETH_2142	1.458e-128	414.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4DXT8@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158416_k127_3729786_1	2074.JNYD01000003_gene3966	1.584e-241	760.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4DZA8@85010|Pseudonocardiales	201174|Actinobacteria	C	(4Fe-4S) cluster-containing protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158416_k127_3729786_21	235985.BBPN01000011_gene4286	2.756e-59	218.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria,2NIHH@228398|Streptacidiphilus	201174|Actinobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158416_k127_3729786_5	469371.Tbis_1673	7.807e-150	482.0	COG1940@1|root,COG1940@2|Bacteria,2IB2E@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	glcK	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158416_k127_3729786_0	1306990.BARG01000052_gene6151	2.019e-320	1001.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SRR25158416_k127_3729786_26	710111.FraQA3DRAFT_3047	1.257e-11	74.0	COG3247@1|root,COG3247@2|Bacteria,2HU0P@201174|Actinobacteria,4EW3F@85013|Frankiales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158416_k127_3729786_19	28042.GU90_08955	4.71e-67	234.0	COG2220@1|root,COG2220@2|Bacteria,2GNHK@201174|Actinobacteria,4E33I@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase of beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158416_k127_3729786_12	1283283.ATXA01000004_gene4389	7.735e-101	338.0	COG0604@1|root,COG0604@2|Bacteria,2GIWC@201174|Actinobacteria,4EVD6@85013|Frankiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158416_k127_3729786_11	1123226.KB899279_gene2367	8.469e-106	359.0	COG2059@1|root,COG2059@2|Bacteria,1TSKA@1239|Firmicutes,4HBB1@91061|Bacilli,26R6T@186822|Paenibacillaceae	91061|Bacilli	P	ChrA protein	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158416_k127_3729786_18	1206737.BAGF01000058_gene3844	2.52e-74	258.0	COG0526@1|root,COG0526@2|Bacteria,2I38A@201174|Actinobacteria,4FW90@85025|Nocardiaceae	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158416_k127_3729786_20	1150864.MILUP08_41312	4.289e-65	232.0	COG0346@1|root,COG0346@2|Bacteria,2I2S6@201174|Actinobacteria,4DEFJ@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3729786_3	1120949.KB903294_gene4124	3.015e-161	525.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158416_k127_3729786_2	1120949.KB903294_gene4123	1.615e-167	532.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DIYT@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.287	ko:K17818	ko00040,ko01100,map00040,map01100	-	R07143,R07144	RC00102	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_3729786_16	1123023.JIAI01000012_gene9222	5.383e-88	301.0	COG1879@1|root,COG1879@2|Bacteria,2GNSX@201174|Actinobacteria,4E06J@85010|Pseudonocardiales	201174|Actinobacteria	G	Periplasmic binding protein domain	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158416_k127_3729786_17	1121924.ATWH01000005_gene2829	8.334e-76	268.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4FTEI@85023|Microbacteriaceae	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158416_k127_3729786_15	1283299.AUKG01000005_gene36	3.045e-90	305.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CRFV@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158416_k127_3729786_22	1123322.KB904691_gene4345	1.024e-53	203.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_3729786_7	1380386.JIAW01000005_gene1479	4.055e-142	463.0	COG3684@1|root,COG3684@2|Bacteria,2IB7A@201174|Actinobacteria	201174|Actinobacteria	G	DeoC/LacD family aldolase	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158416_k127_3729786_4	1380386.JIAW01000005_gene1478	6.756e-157	508.0	COG1070@1|root,COG1070@2|Bacteria,2IE7F@201174|Actinobacteria,238BH@1762|Mycobacteriaceae	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158416_k127_3729786_10	1380386.JIAW01000005_gene1477	4.411e-118	392.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria,23CJU@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158416_k127_3729786_23	1380386.JIAW01000005_gene1458	5.436e-52	191.0	COG1167@1|root,COG1167@2|Bacteria	2|Bacteria	K	transaminase activity	lysN	-	1.1.3.46,2.6.1.103	ko:K00375,ko:K16422,ko:K16423	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06626,R06633,R06634	RC00006,RC00240,RC01104	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158416_k127_3729786_9	1001240.GY21_06130	4.256e-127	415.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4FKMR@85023|Microbacteriaceae	201174|Actinobacteria	E	Zinc-binding dehydrogenase	-	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SRR25158416_k127_3729786_24	1283299.AUKG01000002_gene5287	4.447e-39	148.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,4CTA5@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158416_k127_3729786_25	309801.trd_A0071	2.105e-14	76.0	COG1359@1|root,COG1359@2|Bacteria,2G9BQ@200795|Chloroflexi	200795|Chloroflexi	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_3734312_2	2002.JOEQ01000074_gene6426	2.312e-60	212.0	COG1917@1|root,COG1917@2|Bacteria,2IIQD@201174|Actinobacteria,4EJQH@85012|Streptosporangiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_3734312_0	1463853.JOHW01000004_gene2420	1.745e-145	475.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158416_k127_3734312_3	1288494.EBAPG3_3660	1.01e-36	145.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158416_k127_3734312_1	263358.VAB18032_11730	1.418e-104	370.0	COG2866@1|root,COG2866@2|Bacteria,2GJ8D@201174|Actinobacteria,4DIG8@85008|Micromonosporales	201174|Actinobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_3749009_8	1206733.BAGC01000040_gene1423	1.981e-28	121.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4FUDW@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the amidase family	bam	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158416_k127_3749009_1	1429046.RR21198_1694	1.466e-184	596.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4G8ND@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_3749009_0	882083.SacmaDRAFT_3025	1.171e-200	638.0	COG1680@1|root,COG1680@2|Bacteria,2I2WV@201174|Actinobacteria,4EDVP@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_3749009_3	1068978.AMETH_3059	2.414e-124	419.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4DZCT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR25158416_k127_3749009_2	479432.Sros_4837	2.239e-177	573.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4EHKU@85012|Streptosporangiales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
SRR25158416_k127_3749009_6	525368.HMPREF0591_4201	2.255e-50	192.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,2343K@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158416_k127_3749009_9	55952.BU52_03435	3.371e-08	58.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158416_k127_3749009_7	1123065.ATWL01000014_gene3462	1.081e-39	152.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
SRR25158416_k127_3749009_4	1120949.KB903298_gene5728	1.162e-89	307.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4DB3Q@85008|Micromonosporales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3749009_5	1394178.AWOO02000059_gene595	9.581e-71	250.0	2C3A2@1|root,2ZZP3@2|Bacteria,2I9BD@201174|Actinobacteria,4EJ3U@85012|Streptosporangiales	201174|Actinobacteria	S	PFAM DoxX family protein	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158416_k127_3756521_1	1151122.AQYD01000007_gene253	9.72e-17	81.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4FM28@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_3756521_0	749927.AMED_3244	1.081e-155	503.0	COG1653@1|root,COG1653@2|Bacteria,2I6SJ@201174|Actinobacteria,4DYE6@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158416_k127_3756521_2	67275.JOAP01000004_gene6653	2.118e-09	61.0	2E62U@1|root,330RX@2|Bacteria,2GTSM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3764702_3	105422.BBPM01000001_gene4763	2.124e-17	83.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,2NKES@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158416_k127_3764702_0	1137269.AZWL01000022_gene3516	1.276e-146	471.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158416_k127_3764702_1	1123322.KB904724_gene1958	2.075e-92	314.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158416_k127_3764702_2	1957.JODX01000001_gene5418	4.606e-18	86.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria	201174|Actinobacteria	L	ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158416_k127_3821613_3	1157637.KB892102_gene1414	1.801e-09	63.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158416_k127_3821613_1	356851.JOAN01000002_gene665	6.64e-39	150.0	2C651@1|root,33X7I@2|Bacteria,2IIQ8@201174|Actinobacteria,4DDMF@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3821613_4	1121946.AUAX01000004_gene715	7.411e-06	49.0	COG2215@1|root,COG2215@2|Bacteria,2H0S3@201174|Actinobacteria,4DAQU@85008|Micromonosporales	201174|Actinobacteria	S	High-affinity nickel-transport protein	-	-	-	-	-	-	-	-	-	-	-	-	NicO
SRR25158416_k127_3821613_0	37919.EP51_00510	2.579e-89	302.0	COG1309@1|root,COG1309@2|Bacteria,2H2I4@201174|Actinobacteria,4G0TP@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_3821613_2	1380390.JIAT01000010_gene3851	1.932e-20	92.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158416_k127_3834301_2	43354.JOIJ01000008_gene2976	1.616e-83	279.0	COG1099@1|root,COG1099@2|Bacteria,2GIUY@201174|Actinobacteria,4DXEH@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-dependent hydrolase with TIM-barrel fold	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
SRR25158416_k127_3834301_1	43354.JOIJ01000008_gene2977	5.702e-156	500.0	COG1082@1|root,COG1082@2|Bacteria,2GN0M@201174|Actinobacteria,4DY94@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158416_k127_3834301_0	1001240.GY21_16385	2.246e-233	728.0	COG1524@1|root,COG1524@2|Bacteria,2GP5S@201174|Actinobacteria,4FRDT@85023|Microbacteriaceae	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158416_k127_3834301_3	208439.AJAP_32570	4.907e-13	68.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria,4E0EN@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158416_k127_3836035_41	1380354.JIAN01000008_gene3290	7.46e-28	121.0	COG1716@1|root,COG1716@2|Bacteria,2GSQ0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3836035_40	1380354.JIAN01000008_gene3290	5.96e-35	143.0	COG1716@1|root,COG1716@2|Bacteria,2GSQ0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3836035_11	1123065.ATWL01000029_gene1934	1.517e-170	556.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiB	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158416_k127_3836035_23	1120950.KB892743_gene3128	3.819e-103	361.0	COG2141@1|root,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria,4DNHJ@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3836035_3	1120950.KB892765_gene5656	0.0	1032.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4DNEA@85009|Propionibacteriales	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158416_k127_3836035_32	1298863.AUEP01000005_gene2659	2.224e-63	222.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,4DQHW@85009|Propionibacteriales	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158416_k127_3836035_26	1123320.KB889629_gene7861	1.528e-94	322.0	COG2208@1|root,COG2208@2|Bacteria,2GNS3@201174|Actinobacteria	201174|Actinobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158416_k127_3836035_22	1246995.AFR_38485	2.067e-118	392.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4DCHD@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158416_k127_3836035_43	512565.AMIS_9820	1.964e-13	74.0	2EGCD@1|root,33A46@2|Bacteria,2GWJX@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158416_k127_3836035_16	1206737.BAGF01000032_gene1874	7.4e-149	481.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4FVI4@85025|Nocardiaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158416_k127_3836035_15	1121019.AUMN01000003_gene1064	2.612e-154	502.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria	201174|Actinobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,NAD_binding_8
SRR25158416_k127_3836035_4	1040989.AWZU01000125_gene3972	2.046e-271	843.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3JTRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158416_k127_3836035_47	1410668.JNKC01000016_gene993	1.574e-05	49.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3836035_46	1003195.SCAT_1743	5.307e-06	51.0	2C821@1|root,3019I@2|Bacteria,2HD9F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3836035_18	1120950.KB892805_gene1495	1.031e-140	460.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4DP8U@85009|Propionibacteriales	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158416_k127_3836035_28	1306174.JODP01000011_gene6693	4.408e-89	301.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158416_k127_3836035_24	1298863.AUEP01000005_gene2652	6.291e-103	341.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4DNRI@85009|Propionibacteriales	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158416_k127_3836035_6	1348663.KCH_27660	5.413e-222	696.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,2M1WE@2063|Kitasatospora	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158416_k127_3836035_1	1048339.KB913029_gene4867	0.0	1352.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4ERSS@85013|Frankiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158416_k127_3836035_13	1123320.KB889629_gene7885	3.788e-166	539.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria	201174|Actinobacteria	H	Folylpolyglutamate synthase	folC	GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2447c	Mur_ligase_C,Mur_ligase_M
SRR25158416_k127_3836035_42	469371.Tbis_2471	6.793e-16	83.0	2E69F@1|root,330XE@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4233)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4233
SRR25158416_k127_3836035_33	1122609.AUGT01000005_gene1643	5.875e-57	201.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4DQR5@85009|Propionibacteriales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR25158416_k127_3836035_27	644283.Micau_2631	1.822e-91	313.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4D8U9@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3836035_21	35754.JNYJ01000087_gene2285	5.364e-122	409.0	COG5002@1|root,COG5002@2|Bacteria,2GP6S@201174|Actinobacteria,4DAA8@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158416_k127_3836035_20	134676.ACPL_1119	4.856e-122	398.0	COG0005@1|root,COG0005@2|Bacteria,2GKGG@201174|Actinobacteria,4DA0V@85008|Micromonosporales	201174|Actinobacteria	F	Purine nucleoside phosphorylase involved in purine salvage	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158416_k127_3836035_2	471852.Tcur_1544	0.0	1125.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4EFRZ@85012|Streptosporangiales	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158416_k127_3836035_7	1157637.KB892096_gene1006	6.195e-215	676.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_3836035_29	351607.Acel_0754	9.201e-86	293.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,4ESGF@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158416_k127_3836035_5	1120950.KB892766_gene5093	6.806e-250	796.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4DPJ7@85009|Propionibacteriales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR25158416_k127_3836035_39	1120950.KB892766_gene5094	3.37e-37	144.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4DRJ6@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158416_k127_3836035_38	479432.Sros_7270	1.285e-41	154.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4EJZP@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158416_k127_3836035_9	1048339.KB913029_gene4850	1.363e-208	664.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4ES3D@85013|Frankiales	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158416_k127_3836035_14	263358.VAB18032_01395	1.927e-157	513.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4DAWQ@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158416_k127_3836035_10	351607.Acel_0761	1.393e-176	562.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4ERK4@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
SRR25158416_k127_3836035_25	68260.JOAY01000009_gene577	1.504e-96	319.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158416_k127_3836035_35	1048339.KB913029_gene4841	3.336e-52	187.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4ESRQ@85013|Frankiales	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158416_k127_3836035_31	494419.ALPM01000060_gene2027	1.926e-64	231.0	COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,1WAE3@1268|Micrococcaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	gpmB	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	3.1.3.85,5.4.2.11	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158416_k127_3836035_45	1312959.KI914666_gene3690	1.979e-06	49.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158416_k127_3836035_37	526225.Gobs_1852	9.097e-42	159.0	2E4RI@1|root,32ZK2@2|Bacteria,2GTNG@201174|Actinobacteria,4EWHW@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3836035_12	216594.MMAR_1373	1.684e-167	542.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,233GJ@1762|Mycobacteriaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,rve,rve_3
SRR25158416_k127_3836035_0	512565.AMIS_44900	0.0	1379.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4D8NI@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	atsB	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
SRR25158416_k127_3836035_19	685727.REQ_18030	1.754e-135	439.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4FW4U@85025|Nocardiaceae	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158416_k127_3836035_36	710685.MycrhN_0998	4.272e-45	168.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	atsB	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
SRR25158416_k127_3836035_30	1121904.ARBP01000018_gene2686	3.367e-83	284.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,47TP1@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158416_k127_3836035_17	512565.AMIS_44900	2.725e-144	463.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4D8NI@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	atsB	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
SRR25158416_k127_3836035_34	1283283.ATXA01000004_gene4289	4.982e-53	187.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	atsB	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
SRR25158416_k127_3836035_8	1380370.JIBA01000018_gene447	2.246e-213	672.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	atsB	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
SRR25158416_k127_3846553_2	1120959.ATXF01000005_gene1452	2.318e-98	323.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4FMB3@85023|Microbacteriaceae	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_3846553_1	1120950.KB892812_gene7083	5.642e-107	359.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4DRW9@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_3846553_3	1120950.KB892812_gene7084	1.285e-42	161.0	COG0590@1|root,COG0590@2|Bacteria,2INAI@201174|Actinobacteria,4DQQ8@85009|Propionibacteriales	201174|Actinobacteria	FJ	MafB19-like deaminase	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158416_k127_3846553_0	479432.Sros_2735	7.241e-137	441.0	COG1266@1|root,COG1266@2|Bacteria,2I2YJ@201174|Actinobacteria,4EIQQ@85012|Streptosporangiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158416_k127_3846553_4	479432.Sros_2735	1.409e-05	51.0	COG1266@1|root,COG1266@2|Bacteria,2I2YJ@201174|Actinobacteria,4EIQQ@85012|Streptosporangiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158416_k127_3859471_0	1385520.N802_02040	4.941e-202	633.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4FEJG@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158416_k127_3859471_1	909613.UO65_5874	2.154e-76	266.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4DYX5@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigJ	GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158416_k127_3859471_3	1380356.JNIK01000018_gene578	5.208e-34	139.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria	201174|Actinobacteria	L	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158416_k127_3859471_4	1352941.M877_29570	2.574e-32	128.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158416_k127_3859471_5	1229780.BN381_130139	1.769e-27	118.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158416_k127_3859471_2	1122622.ATWJ01000002_gene794	1.517e-35	141.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158416_k127_3863454_0	103733.JNYO01000008_gene5417	1.742e-212	672.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2HEQP@201174|Actinobacteria,4DYQU@85010|Pseudonocardiales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158416_k127_3874486_4	1380370.JIBA01000017_gene2940	3.213e-25	106.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4FGDB@85021|Intrasporangiaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_3874486_3	211114.JOEF01000006_gene2422	2.322e-33	139.0	COG1708@1|root,COG1708@2|Bacteria,2IFWR@201174|Actinobacteria,4E40Z@85010|Pseudonocardiales	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158416_k127_3874486_1	1206741.BAFX01000075_gene3784	1.88e-90	306.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4G8PH@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158416_k127_3874486_2	1122138.AQUZ01000003_gene593	2.363e-46	181.0	COG0640@1|root,COG0640@2|Bacteria,2GP04@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_3874486_0	675635.Psed_0562	0.0	1067.0	COG0365@1|root,COG0365@2|Bacteria,2GP7N@201174|Actinobacteria,4DXMV@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA synthetase AMP-acid ligase	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158416_k127_3874486_5	1283287.KB822577_gene3054	3.013e-07	54.0	COG1295@1|root,COG1295@2|Bacteria,2H11D@201174|Actinobacteria,4DUCX@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158416_k127_3876874_12	570268.ANBB01000004_gene144	2.56e-85	292.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4EN0R@85012|Streptosporangiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158416_k127_3876874_1	1048339.KB913029_gene3997	1.653e-228	726.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4ERHY@85013|Frankiales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158416_k127_3876874_3	1348663.KCH_13550	8.668e-204	640.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,2M0C3@2063|Kitasatospora	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158416_k127_3876874_5	996637.SGM_3790	6.783e-183	579.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158416_k127_3876874_17	1298863.AUEP01000012_gene3757	8.171e-40	149.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4DRNP@85009|Propionibacteriales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158416_k127_3876874_14	561175.KB894098_gene5479	7.033e-68	235.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4EGNM@85012|Streptosporangiales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158416_k127_3876874_16	1123322.KB904705_gene30	6.813e-44	161.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3876874_10	1210045.ALNP01000016_gene1943	1.964e-102	346.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158416_k127_3876874_9	1137268.AZXF01000032_gene4109	1.269e-119	399.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4EHA4@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.5.2,1.3.98.1	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158416_k127_3876874_0	1120950.KB892708_gene4316	0.0	1733.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4DNSQ@85009|Propionibacteriales	201174|Actinobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158416_k127_3876874_4	196162.Noca_2430	1.233e-185	588.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4DNY4@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158416_k127_3876874_18	1123322.KB904705_gene35	5.901e-24	113.0	COG0505@1|root,COG0505@2|Bacteria,2GM9I@201174|Actinobacteria	201174|Actinobacteria	EF	Belongs to the CarA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3876874_2	1122609.AUGT01000002_gene3995	1.519e-207	655.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4DMZJ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158416_k127_3876874_7	1146883.BLASA_2360	4.225e-149	485.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4ES0C@85013|Frankiales	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158416_k127_3876874_13	266940.Krad_3006	1.768e-78	267.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158416_k127_3876874_15	1122138.AQUZ01000037_gene5528	4.231e-55	196.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4DR4N@85009|Propionibacteriales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158416_k127_3876874_11	1095767.CAHD01000205_gene863	9.184e-97	319.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4F0V8@85016|Cellulomonadaceae	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158416_k127_3876874_8	479433.Caci_2392	2.442e-123	405.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158416_k127_3876874_6	1123322.KB904647_gene1627	1.331e-167	534.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158416_k127_3890394_7	1125971.ASJB01000065_gene6210	2.884e-112	365.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4DZNN@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158416_k127_3890394_10	500153.JOEK01000003_gene1029	2.134e-71	245.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158416_k127_3890394_13	1120950.KB892784_gene182	1.389e-54	205.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4DQN0@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158416_k127_3890394_2	1120950.KB892784_gene183	2.943e-197	625.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4DNFP@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158416_k127_3890394_6	1120950.KB892784_gene185	4.021e-140	452.0	COG1072@1|root,COG1072@2|Bacteria,2GIRR@201174|Actinobacteria,4DPFH@85009|Propionibacteriales	201174|Actinobacteria	H	pantothenate kinase activity	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158416_k127_3890394_0	1968.JOEV01000018_gene2668	4.111e-317	982.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158416_k127_3890394_15	1120950.KB892784_gene189	8.217e-40	159.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,4DRCQ@85009|Propionibacteriales	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158416_k127_3890394_5	1120950.KB892784_gene190	4.475e-142	477.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4DN6W@85009|Propionibacteriales	201174|Actinobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158416_k127_3890394_4	1120950.KB892784_gene193	5.413e-148	477.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4DNHM@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158416_k127_3890394_9	1120950.KB892784_gene194	3.952e-105	378.0	COG2267@1|root,COG2267@2|Bacteria,2GMCK@201174|Actinobacteria,4DNK4@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_3890394_12	58123.JOFJ01000024_gene3446	1.214e-56	203.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4EIYV@85012|Streptosporangiales	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158416_k127_3890394_11	1120950.KB892784_gene197	6.211e-68	238.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4DQ98@85009|Propionibacteriales	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158416_k127_3890394_16	1306174.JODP01000006_gene3617	1.052e-36	145.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria	201174|Actinobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158416_k127_3890394_3	196162.Noca_3657	2.233e-169	541.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4DP6P@85009|Propionibacteriales	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158416_k127_3890394_14	1306174.JODP01000006_gene3620	6.786e-46	169.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158416_k127_3890394_1	469371.Tbis_0620	9.384e-259	807.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DYFQ@85010|Pseudonocardiales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158416_k127_3890394_8	1386089.N865_10190	2.668e-106	349.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4FEEH@85021|Intrasporangiaceae	201174|Actinobacteria	E	Aminotransferase	dapC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.6.1.1,2.6.1.17	ko:K00812,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv0858c	Aminotran_1_2
SRR25158416_k127_3901426_2	1869.MB27_01965	6.053e-45	168.0	2CC52@1|root,2ZMEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3901426_1	1032480.MLP_07490	1.188e-67	237.0	COG2442@1|root,COG2442@2|Bacteria,2IQVM@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158416_k127_3901426_0	1380390.JIAT01000009_gene1628	1.154e-132	464.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_3901426_4	287986.DV20_16465	6.864e-07	51.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4DXV5@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158416_k127_3903740_4	1236902.ANAS01000005_gene4634	1.257e-50	181.0	COG0524@1|root,COG0524@2|Bacteria,2GKQP@201174|Actinobacteria,4EFND@85012|Streptosporangiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	scrK	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158416_k127_3903740_1	1122611.KB903944_gene1220	2.414e-153	501.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4EK1W@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158416_k127_3903740_2	479435.Kfla_5625	2.755e-123	403.0	COG1175@1|root,COG1175@2|Bacteria,2GJZD@201174|Actinobacteria,4DPP8@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158416_k127_3903740_3	479435.Kfla_5624	7.175e-107	352.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4DPVF@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158416_k127_3903740_0	1120950.KB892741_gene2716	0.0	1223.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DN2T@85009|Propionibacteriales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158416_k127_3903740_7	1380346.JNIH01000008_gene1427	1.451e-15	79.0	2ENN7@1|root,33G9I@2|Bacteria,2IQG5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3903740_6	570268.ANBB01000022_gene5234	6.884e-24	108.0	COG1254@1|root,COG1254@2|Bacteria,2IQ4M@201174|Actinobacteria,4EKC4@85012|Streptosporangiales	201174|Actinobacteria	C	Acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158416_k127_3903740_5	743718.Isova_2086	2.412e-49	177.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4F39C@85017|Promicromonosporaceae	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_3915486_3	1120950.KB892823_gene493	7.102e-46	169.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4DPN8@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158416_k127_3915486_4	1120950.KB892764_gene5639	7.377e-30	132.0	COG3832@1|root,COG3832@2|Bacteria,2GS2W@201174|Actinobacteria,4DSAG@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
SRR25158416_k127_3915486_1	479435.Kfla_1675	1.051e-120	392.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4DN3M@85009|Propionibacteriales	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158416_k127_3915486_0	479435.Kfla_1682	0.0	1953.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4DNQX@85009|Propionibacteriales	201174|Actinobacteria	E	Bacterial NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158416_k127_3915486_2	1120950.KB892764_gene5641	2.349e-53	192.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4DN91@85009|Propionibacteriales	201174|Actinobacteria	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158416_k127_3980861_1	110319.CF8_3771	8.145e-142	457.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4DPII@85009|Propionibacteriales	201174|Actinobacteria	V	FemAB family	femX	-	2.3.2.10	ko:K05363,ko:K18354	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	R08779	RC00055,RC00096	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	FemAB
SRR25158416_k127_3980861_2	1120950.KB892740_gene2551	1.011e-109	364.0	COG0787@1|root,COG0787@2|Bacteria,2GJJX@201174|Actinobacteria,4DNS3@85009|Propionibacteriales	201174|Actinobacteria	M	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
SRR25158416_k127_3980861_0	369723.Strop_1747	7.603e-145	470.0	COG0531@1|root,COG0531@2|Bacteria,2GJ1D@201174|Actinobacteria,4DB22@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158416_k127_3987500_1	1268303.RHODMAR_2288	1.894e-46	182.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4FYSB@85025|Nocardiaceae	201174|Actinobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158416_k127_3987500_0	685727.REQ_32040	5.767e-320	996.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4FVXQ@85025|Nocardiaceae	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158416_k127_3987500_2	1206720.BAFQ01000053_gene1365	1.003e-05	50.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4FUZR@85025|Nocardiaceae	201174|Actinobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158416_k127_3990076_60	269800.Tfu_1450	1.643e-30	130.0	2ETKA@1|root,33M3Y@2|Bacteria,2H03F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3990076_51	1306174.JODP01000006_gene3393	1.814e-43	162.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158416_k127_3990076_4	743718.Isova_2620	6.647e-165	527.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4F3YC@85017|Promicromonosporaceae	201174|Actinobacteria	E	ABC transporter	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158416_k127_3990076_3	471853.Bcav_0782	3.107e-168	542.0	COG3642@1|root,COG3642@2|Bacteria,2GIX0@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158416_k127_3990076_5	471852.Tcur_2886	2.278e-162	518.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4EGIK@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_3990076_54	1120950.KB892823_gene537	4.022e-41	163.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4DS6I@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3990076_22	1306174.JODP01000006_gene3389	5.105e-106	355.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158416_k127_3990076_1	1033730.CAHG01000008_gene3234	2.824e-229	717.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4DP8C@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158416_k127_3990076_36	443218.AS9A_0347	4.052e-67	233.0	COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,232FK@1762|Mycobacteriaceae	201174|Actinobacteria	P	reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158416_k127_3990076_42	500153.JOEK01000003_gene952	5.924e-63	224.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria	201174|Actinobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3581c	YgbB
SRR25158416_k127_3990076_37	479433.Caci_8146	9.469e-67	235.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158416_k127_3990076_29	1048339.KB913029_gene2036	2.463e-88	293.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4ES60@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, CarD family	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158416_k127_3990076_44	1306406.ASHX01000002_gene5228	3.428e-61	222.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria	201174|Actinobacteria	H	Pfam UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158416_k127_3990076_12	67315.JOBD01000007_gene3551	3.069e-119	387.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158416_k127_3990076_10	1169161.KB897713_gene6591	3.46e-125	414.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158416_k127_3990076_40	1380356.JNIK01000018_gene757	1.758e-64	230.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4ESDP@85013|Frankiales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158416_k127_3990076_46	1122138.AQUZ01000042_gene3360	1.214e-57	215.0	COG5340@1|root,COG5340@2|Bacteria,2II40@201174|Actinobacteria,4DR8H@85009|Propionibacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158416_k127_3990076_9	1120950.KB892790_gene2083	1.242e-133	428.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4DND2@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158416_k127_3990076_43	1033730.CAHG01000008_gene3223	1.49e-61	218.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4DQQM@85009|Propionibacteriales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158416_k127_3990076_41	935866.JAER01000006_gene3295	4.771e-64	224.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4DR0K@85009|Propionibacteriales	201174|Actinobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158416_k127_3990076_16	1032480.MLP_02100	4.155e-116	384.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DP9F@85009|Propionibacteriales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158416_k127_3990076_21	263358.VAB18032_02030	1.028e-107	360.0	COG2872@1|root,COG2872@2|Bacteria,2I8P6@201174|Actinobacteria,4DAMA@85008|Micromonosporales	201174|Actinobacteria	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR25158416_k127_3990076_64	1306174.JODP01000006_gene3373	5.073e-21	103.0	2EHMU@1|root,33BDI@2|Bacteria,2GQGA@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
SRR25158416_k127_3990076_69	1056816.JAFQ01000004_gene2438	4.197e-06	58.0	2EBKM@1|root,335M1@2|Bacteria,2I5HJ@201174|Actinobacteria,4FV4K@85025|Nocardiaceae	201174|Actinobacteria	S	Heparin-binding hemagglutinin	hbhA	GO:0003674,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007155,GO:0007157,GO:0008150,GO:0008201,GO:0009986,GO:0016020,GO:0022610,GO:0030100,GO:0030312,GO:0032879,GO:0035821,GO:0042802,GO:0043167,GO:0043168,GO:0044003,GO:0044068,GO:0044077,GO:0044078,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045807,GO:0048259,GO:0048260,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051701,GO:0051704,GO:0051817,GO:0060627,GO:0065007,GO:0071944,GO:0097367,GO:0098609,GO:0098742,GO:1901681	-	ko:K16645	-	-	-	-	ko00000,ko00536	-	-	-	-
SRR25158416_k127_3990076_53	1120936.KB907215_gene4054	2.353e-41	154.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria,4EJT0@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158416_k127_3990076_27	1123320.KB889665_gene1374	3.136e-91	317.0	COG3387@1|root,COG3387@2|Bacteria,2ICV9@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3990076_45	926554.KI912654_gene4430	4.321e-58	207.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_3990076_19	1120950.KB892790_gene2095	9.554e-111	366.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4DNR5@85009|Propionibacteriales	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158416_k127_3990076_47	1078020.KEK_06012	2.238e-55	201.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,239CY@1762|Mycobacteriaceae	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158416_k127_3990076_8	1120950.KB892795_gene2294	5.537e-135	437.0	COG0404@1|root,COG0404@2|Bacteria,2I4ER@201174|Actinobacteria,4DX1V@85009|Propionibacteriales	201174|Actinobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158416_k127_3990076_49	1122611.KB903970_gene2598	1.034e-53	191.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4EJ9C@85012|Streptosporangiales	201174|Actinobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158416_k127_3990076_38	479433.Caci_8243	3.755e-65	228.0	COG4044@1|root,COG4044@2|Bacteria,2GKGF@201174|Actinobacteria	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1794
SRR25158416_k127_3990076_48	106370.Francci3_0454	1.574e-54	195.0	COG2044@1|root,COG2044@2|Bacteria,2IHT6@201174|Actinobacteria,4EVHU@85013|Frankiales	201174|Actinobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158416_k127_3990076_61	1298863.AUEP01000010_gene4545	2.622e-28	123.0	2E40M@1|root,32YXE@2|Bacteria,2GRE0@201174|Actinobacteria,4DSEX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3990076_59	1229203.KI301992_gene2169	1.689e-31	127.0	2E36U@1|root,32Y6I@2|Bacteria,2IM2G@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1416)	sseC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1416
SRR25158416_k127_3990076_7	1032480.MLP_47660	1.193e-147	484.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4DPRJ@85009|Propionibacteriales	201174|Actinobacteria	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158416_k127_3990076_52	436229.JOEH01000023_gene761	4.911e-43	162.0	2AN8T@1|root,327DN@2|Bacteria,2I81P@201174|Actinobacteria,2NNJW@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158416_k127_3990076_57	1463909.KL585946_gene1423	3.205e-37	148.0	COG0526@1|root,COG0526@2|Bacteria,2IKMI@201174|Actinobacteria	201174|Actinobacteria	CO	Thioredoxin	thiX	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
SRR25158416_k127_3990076_63	452652.KSE_18390	1.059e-21	106.0	COG5662@1|root,COG5662@2|Bacteria,2GNZG@201174|Actinobacteria,2M35P@2063|Kitasatospora	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_3990076_39	1120950.KB892777_gene734	5.655e-65	229.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,4DR2Y@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	sigL	GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158416_k127_3990076_62	73044.JNXP01000002_gene2102	2.72e-24	106.0	COG1977@1|root,COG1977@2|Bacteria,2IQIT@201174|Actinobacteria	201174|Actinobacteria	H	Molybdopterin converting factor, small subunit	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158416_k127_3990076_35	235985.BBPN01000095_gene2744	1.283e-67	243.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,2NEQE@228398|Streptacidiphilus	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_3990076_20	1048339.KB913029_gene2009	6.04e-110	363.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4ERJ7@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158416_k127_3990076_26	1394178.AWOO02000065_gene127	6.756e-93	318.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4EHNC@85012|Streptosporangiales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158416_k127_3990076_0	1120950.KB892777_gene739	0.0	1015.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4DNIH@85009|Propionibacteriales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158416_k127_3990076_28	1304865.JAGF01000001_gene2382	1.02e-90	317.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria	201174|Actinobacteria	S	CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158416_k127_3990076_34	2045.KR76_22975	5.313e-71	253.0	COG1051@1|root,COG2062@1|root,COG1051@2|Bacteria,COG2062@2|Bacteria,2I2N2@201174|Actinobacteria,4DWX8@85009|Propionibacteriales	201174|Actinobacteria	FT	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158416_k127_3990076_18	219305.MCAG_02726	7.422e-112	372.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,4DB6Z@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158416_k127_3990076_11	1146883.BLASA_4538	1.147e-119	395.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
SRR25158416_k127_3990076_14	1146883.BLASA_4537	9.644e-119	394.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158416_k127_3990076_23	2002.JOEQ01000048_gene7446	1.397e-100	350.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4EN8Q@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158416_k127_3990076_17	326427.Cagg_3638	4.882e-114	375.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi,3751I@32061|Chloroflexia	32061|Chloroflexia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158416_k127_3990076_58	266940.Krad_0784	7.472e-35	141.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158416_k127_3990076_50	1120960.ATXG01000008_gene212	1.057e-50	186.0	COG1619@1|root,COG1619@2|Bacteria,2GNW5@201174|Actinobacteria	201174|Actinobacteria	V	proteins homologs of microcin C7 resistance protein MccF	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158416_k127_3990076_66	1120960.ATXG01000008_gene212	7.775e-15	77.0	COG1619@1|root,COG1619@2|Bacteria,2GNW5@201174|Actinobacteria	201174|Actinobacteria	V	proteins homologs of microcin C7 resistance protein MccF	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158416_k127_3990076_55	1869.MB27_17745	8.258e-40	156.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4DIRI@85008|Micromonosporales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158416_k127_3990076_13	1120934.KB894436_gene4372	5.107e-119	392.0	COG0182@1|root,COG0182@2|Bacteria,2GJJA@201174|Actinobacteria,4DZKT@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,IF-2B
SRR25158416_k127_3990076_30	1464048.JNZS01000006_gene4214	1.318e-85	289.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria,4D8N7@85008|Micromonosporales	201174|Actinobacteria	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158416_k127_3990076_32	35754.JNYJ01000015_gene8425	1.477e-79	280.0	COG4585@1|root,COG4585@2|Bacteria,2GKRM@201174|Actinobacteria,4DCUP@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158416_k127_3990076_31	1380390.JIAT01000009_gene1024	2.358e-83	284.0	COG0842@1|root,COG0842@2|Bacteria,2GK5F@201174|Actinobacteria,4CQVB@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR25158416_k127_3990076_24	326424.FRAAL4807	8.142e-98	336.0	COG1131@1|root,COG1131@2|Bacteria,2GJ0Y@201174|Actinobacteria,4ES5Y@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_3990076_65	235985.BBPN01000009_gene3735	1.677e-20	102.0	COG0500@1|root,COG2226@2|Bacteria,2HNBG@201174|Actinobacteria,2NI06@228398|Streptacidiphilus	201174|Actinobacteria	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_3990076_2	358823.DF19_18885	3.985e-179	576.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158416_k127_3990076_6	675635.Psed_2916	1.019e-148	478.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4E1VE@85010|Pseudonocardiales	201174|Actinobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158416_k127_3990076_33	28444.JODQ01000002_gene4551	2.127e-78	268.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4EGZ9@85012|Streptosporangiales	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158416_k127_3990076_25	313589.JNB_16484	3.824e-95	335.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4FE5H@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158416_k127_3990076_56	1121272.KB903283_gene5169	6.864e-39	151.0	COG0346@1|root,COG0346@2|Bacteria,2GS59@201174|Actinobacteria,4DGI8@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158416_k127_3990076_15	471852.Tcur_3819	1.803e-116	377.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4EIBK@85012|Streptosporangiales	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158416_k127_3991786_1	1150864.MILUP08_45777	9.981e-21	95.0	2EBG9@1|root,335GU@2|Bacteria,2IJZI@201174|Actinobacteria,4DDQ4@85008|Micromonosporales	201174|Actinobacteria	S	sigma 54 modulation protein ribosomal protein S30EA	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
SRR25158416_k127_3991786_2	196162.Noca_2293	3.113e-16	85.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_3991786_0	298654.FraEuI1c_0249	1.523e-37	152.0	2B5NI@1|root,31YHW@2|Bacteria,2GWI6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158416_k127_3991914_8	1121924.ATWH01000011_gene257	0.0002294	44.0	COG2314@1|root,COG2314@2|Bacteria,2ICDQ@201174|Actinobacteria	201174|Actinobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
SRR25158416_k127_3991914_2	1380370.JIBA01000015_gene318	4.642e-82	288.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4FFEB@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_3991914_7	1536774.H70357_27200	6.645e-16	88.0	COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,4HA1I@91061|Bacilli,274N2@186822|Paenibacillaceae	91061|Bacilli	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158416_k127_3991914_9	216594.MMAR_2827	0.0007445	47.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,237QK@1762|Mycobacteriaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	ko:K18372	ko00640,map00640	-	R10705	RC00460,RC00461	ko00000,ko00001,ko01000	-	-	-	Beta-lactamase
SRR25158416_k127_3991914_0	1713.JOFV01000002_gene592	1.084e-120	411.0	COG2385@1|root,COG5479@1|root,COG5640@1|root,COG2385@2|Bacteria,COG5479@2|Bacteria,COG5640@2|Bacteria,2GNDB@201174|Actinobacteria,4F2JD@85016|Cellulomonadaceae	201174|Actinobacteria	DM	Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme.	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,FG-GAP
SRR25158416_k127_3991914_5	469383.Cwoe_1984	2.403e-41	154.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4CU4D@84995|Rubrobacteria	84995|Rubrobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158416_k127_3991914_6	1184609.KILIM_015_01030	1.74e-39	161.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_3991914_3	1122939.ATUD01000002_gene1481	5.436e-76	269.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4CQ63@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158416_k127_3991914_1	1464048.JNZS01000009_gene5674	4.209e-90	310.0	COG3178@1|root,COG3178@2|Bacteria,2GNRB@201174|Actinobacteria,4DD76@85008|Micromonosporales	201174|Actinobacteria	S	'Phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_3991914_4	645465.ACUR01000149_gene3247	1.446e-41	156.0	COG1391@1|root,COG1391@2|Bacteria,2IBJS@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	-	-	-	-	-	-	-	-	-	-	-	-	GlnD_UR_UTase,GlnE
SRR25158416_k127_3992782_14	1120950.KB892759_gene6225	4.213e-84	281.0	COG5285@1|root,COG5285@2|Bacteria,2HZP9@201174|Actinobacteria,4DTG4@85009|Propionibacteriales	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158416_k127_3992782_5	66874.JOFS01000017_gene3528	2.202e-156	505.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
SRR25158416_k127_3992782_7	479435.Kfla_1268	4.037e-141	456.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,4DNTC@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10228	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
SRR25158416_k127_3992782_9	1968.JOEV01000011_gene2085	2.713e-111	370.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_3992782_2	1122138.AQUZ01000022_gene8696	9.526e-236	745.0	COG1012@1|root,COG1012@2|Bacteria,2GNJJ@201174|Actinobacteria,4DQ0E@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158416_k127_3992782_18	369723.Strop_2146	9.27e-70	247.0	COG0715@1|root,COG0715@2|Bacteria,2GN9B@201174|Actinobacteria,4DBTW@85008|Micromonosporales	201174|Actinobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
SRR25158416_k127_3992782_22	1122182.KB903837_gene3895	2.364e-37	144.0	COG3861@1|root,COG3861@2|Bacteria,2IQ4Y@201174|Actinobacteria,4DF3X@85008|Micromonosporales	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_3992782_19	710696.Intca_2629	8.256e-68	252.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FFZV@85021|Intrasporangiaceae	201174|Actinobacteria	DM	biosynthesis protein	-	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,Wzz
SRR25158416_k127_3992782_15	463191.SSEG_03706	4.6e-81	276.0	COG3620@1|root,COG3837@1|root,COG3620@2|Bacteria,COG3837@2|Bacteria,2I4X7@201174|Actinobacteria	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158416_k127_3992782_0	351607.Acel_1043	1.161e-261	809.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,4ESAX@85013|Frankiales	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158416_k127_3992782_13	469383.Cwoe_1033	1.139e-86	302.0	COG1071@1|root,COG1071@2|Bacteria,2IC03@201174|Actinobacteria,4CQ7Q@84995|Rubrobacteria	2|Bacteria	C	PFAM dehydrogenase, E1 component	-	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158416_k127_3992782_4	358823.DF19_10400	8.715e-171	543.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158416_k127_3992782_1	351607.Acel_1042	1.438e-243	764.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4ESKE@85013|Frankiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158416_k127_3992782_8	351607.Acel_1041	2.013e-134	433.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_3992782_12	351607.Acel_1040	4.657e-98	331.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria,4EVQ5@85013|Frankiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158416_k127_3992782_17	1463917.JODC01000007_gene7461	1.356e-79	281.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158416_k127_3992782_6	1037409.BJ6T_32830	2.303e-149	482.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,2TS8X@28211|Alphaproteobacteria,3JSD9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	glutaminase activity	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
SRR25158416_k127_3992782_23	266117.Rxyl_1185	3.378e-36	143.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4CTDX@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158416_k127_3992782_10	1380390.JIAT01000009_gene613	2.269e-107	355.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria,4CSK9@84995|Rubrobacteria	84995|Rubrobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158416_k127_3992782_16	1120950.KB892747_gene3703	4.816e-81	291.0	COG1011@1|root,COG1011@2|Bacteria,2HZ7F@201174|Actinobacteria,4DQFA@85009|Propionibacteriales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase_like
SRR25158416_k127_3992782_11	263358.VAB18032_05720	2.059e-101	340.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4D93X@85008|Micromonosporales	201174|Actinobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_3992782_3	1150864.MILUP08_42270	3.169e-187	597.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4D9FD@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-associated	fdhA	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158416_k127_3992782_21	930171.Asphe3_21370	4.33e-60	211.0	COG0517@1|root,COG0517@2|Bacteria,2IM3K@201174|Actinobacteria,1W9M9@1268|Micrococcaceae	201174|Actinobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158416_k127_3992782_20	930171.Asphe3_21370	3.348e-62	218.0	COG0517@1|root,COG0517@2|Bacteria,2IM3K@201174|Actinobacteria,1W9M9@1268|Micrococcaceae	201174|Actinobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158416_k127_3992782_25	1283283.ATXA01000023_gene251	8.702e-05	45.0	COG3576@1|root,COG3576@2|Bacteria,2I2W4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158416_k127_3992782_24	1385520.N802_01985	2.531e-05	53.0	2F925@1|root,341DU@2|Bacteria,2GS22@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4001288_28	1298863.AUEP01000003_gene2725	0.0001291	46.0	2DBMF@1|root,2Z9YG@2|Bacteria,2HZ6S@201174|Actinobacteria,4DPP0@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4001288_5	222534.KB893750_gene4365	1.583e-143	490.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158416_k127_4001288_10	1206737.BAGF01000149_gene6002	5.36e-95	313.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4FUV9@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_4001288_19	2002.JOEQ01000035_gene6706	2.886e-47	173.0	2E5NA@1|root,330D3@2|Bacteria,2IQ91@201174|Actinobacteria,4EK6C@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRR25158416_k127_4001288_7	477641.MODMU_2211	5.11e-108	361.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4ES2V@85013|Frankiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158416_k127_4001288_22	1122138.AQUZ01000016_gene283	8.123e-32	128.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158416_k127_4001288_12	1449976.KALB_8361	3.963e-87	299.0	COG0665@1|root,COG0665@2|Bacteria,2GN2M@201174|Actinobacteria,4E48U@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	aao	GO:0003674,GO:0003824,GO:0003884,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046416,GO:0055114,GO:0071704,GO:1901564,GO:1901605	1.4.3.3	ko:K00273	ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146	-	R00366,R02457,R02894,R02923,R04221,R07400	RC00006,RC00018,RC00135	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158416_k127_4001288_13	219305.MCAG_04580	3.804e-79	267.0	COG0346@1|root,COG0346@2|Bacteria,2IK75@201174|Actinobacteria,4DD54@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_4001288_16	455632.SGR_2450	5.143e-53	197.0	COG1512@1|root,COG1512@2|Bacteria,2GMGW@201174|Actinobacteria	201174|Actinobacteria	M	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
SRR25158416_k127_4001288_1	1150864.MILUP08_41514	5.6e-230	724.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4DB0E@85008|Micromonosporales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158416_k127_4001288_0	479435.Kfla_5184	0.0	1725.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DN7Q@85009|Propionibacteriales	201174|Actinobacteria	C	2-oxoglutarate dehydrogenase	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158416_k127_4001288_24	67373.JOBF01000013_gene4392	3.926e-23	98.0	2E460@1|root,32Z20@2|Bacteria,2GQGS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4001288_17	266940.Krad_1227	1.025e-48	182.0	COG2755@1|root,COG2755@2|Bacteria,2IA8J@201174|Actinobacteria	201174|Actinobacteria	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158416_k127_4001288_4	1120950.KB892749_gene3298	3.039e-144	465.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4DN65@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	adh3	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_4001288_26	1133850.SHJG_8337	2.125e-06	55.0	2E6NT@1|root,33198@2|Bacteria,2IFTP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4001288_25	1120950.KB892748_gene3254	1.436e-14	81.0	2913Q@1|root,2ZNR4@2|Bacteria,2HD32@201174|Actinobacteria,4DW4A@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4001288_18	1123251.ATWM01000001_gene817	1.732e-48	180.0	COG3409@1|root,COG3409@2|Bacteria,2IM37@201174|Actinobacteria,4FHJ0@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4001288_15	1157637.KB892105_gene1915	4.801e-59	211.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria	201174|Actinobacteria	L	Pfam NUDIX	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158416_k127_4001288_23	1298863.AUEP01000001_gene865	1.096e-28	118.0	COG0681@1|root,COG0681@2|Bacteria,2I3M4@201174|Actinobacteria,4DSA2@85009|Propionibacteriales	201174|Actinobacteria	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158416_k127_4001288_14	1121926.AXWO01000002_gene1616	6.885e-63	219.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4EYHD@85014|Glycomycetales	201174|Actinobacteria	S	Nickel-containing superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158416_k127_4001288_21	479433.Caci_7707	2.697e-35	138.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158416_k127_4001288_8	1048339.KB913029_gene3302	1.854e-107	354.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4ES7X@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158416_k127_4001288_27	1156844.KB891850_gene3060	4.824e-06	53.0	2DTKM@1|root,33KSC@2|Bacteria,2IHXR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4001288_9	1123320.KB889737_gene5367	1.693e-104	351.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158416_k127_4001288_20	1123320.KB889737_gene5366	6.061e-44	160.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158416_k127_4001288_3	1120950.KB892749_gene3308	6.373e-194	620.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4DPYA@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
SRR25158416_k127_4001288_11	1120950.KB892749_gene3309	5.919e-92	311.0	2DM3D@1|root,31J5I@2|Bacteria,2I578@201174|Actinobacteria,4DWXX@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
SRR25158416_k127_4001288_2	1120950.KB892749_gene3313	7.342e-228	722.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4DPFV@85009|Propionibacteriales	201174|Actinobacteria	EH	TPP binding domain protein	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158416_k127_4001288_6	1123319.AUBE01000004_gene601	2.913e-118	392.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158416_k127_4004611_4	1120949.KB903295_gene2316	1.269e-165	534.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DBP3@85008|Micromonosporales	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0030312,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,Trp_halogenase
SRR25158416_k127_4004611_1	67267.JNXT01000014_gene310	4.704e-232	729.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158416_k127_4004611_3	1121272.KB903249_gene1627	1.524e-194	615.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,2HU5Q@201174|Actinobacteria,4DBMT@85008|Micromonosporales	201174|Actinobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR25158416_k127_4004611_15	1205680.CAKO01000038_gene1918	1.063e-59	224.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,1R65I@1224|Proteobacteria,2TV92@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
SRR25158416_k127_4004611_13	1121272.KB903249_gene1629	8.835e-63	224.0	COG1309@1|root,COG1309@2|Bacteria,2IHGM@201174|Actinobacteria,4DD7T@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_4004611_22	1211815.CBYP010000016_gene2642	8.71e-26	111.0	2E4PM@1|root,32P93@2|Bacteria,2I85P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4004611_11	345341.KUTG_03678	3.822e-95	322.0	COG0627@1|root,COG0627@2|Bacteria,2GJX4@201174|Actinobacteria,4E3YS@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158416_k127_4004611_25	1121946.AUAX01000017_gene5107	1.104e-12	74.0	COG2267@1|root,COG2267@2|Bacteria,2I9JC@201174|Actinobacteria,4DC8R@85008|Micromonosporales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_4004611_23	1121272.KB903272_gene86	1.933e-19	90.0	COG2267@1|root,COG2267@2|Bacteria,2I9JC@201174|Actinobacteria,4DC8R@85008|Micromonosporales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_4004611_20	1313172.YM304_06550	2.243e-32	136.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158416_k127_4004611_6	479434.Sthe_1230	1.31e-141	461.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158416_k127_4004611_21	1449044.JMLE01000002_gene4321	8.846e-32	128.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4004611_5	351607.Acel_0354	6.11e-148	476.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158416_k127_4004611_9	351607.Acel_0353	1.372e-118	388.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4ETUW@85013|Frankiales	201174|Actinobacteria	G	Monosaccharide ABC transporter ATP-binding protein, CUT2 family	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158416_k127_4004611_7	351607.Acel_0352	9.269e-137	442.0	COG1172@1|root,COG1172@2|Bacteria,2HFUN@201174|Actinobacteria,4EWA1@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158416_k127_4004611_10	1120949.KB903305_gene7200	1.563e-96	328.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_4004611_24	996637.SGM_2046	1.717e-15	86.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0126
SRR25158416_k127_4004611_26	479431.Namu_4088	3.146e-05	52.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158416_k127_4004611_0	710111.FraQA3DRAFT_5369	1.854e-254	798.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4EUQJ@85013|Frankiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158416_k127_4004611_14	1463926.JOCA01000002_gene5636	6.314e-60	217.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158416_k127_4004611_19	1121946.AUAX01000012_gene6695	1.58e-48	181.0	COG1028@1|root,COG1028@2|Bacteria,2IFUD@201174|Actinobacteria,4D8PP@85008|Micromonosporales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158416_k127_4004611_12	1463926.JOCA01000002_gene5637	2.909e-85	289.0	COG0302@1|root,COG0302@2|Bacteria,2H2JE@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase I	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydroI
SRR25158416_k127_4004611_18	287986.DV20_10485	5.064e-49	183.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4E2MZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_4004611_8	1122138.AQUZ01000008_gene3640	1.307e-119	389.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4DNG2@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158416_k127_4004611_16	390989.JOEG01000008_gene1479	1.067e-56	203.0	COG4978@1|root,COG4978@2|Bacteria,2IKYA@201174|Actinobacteria,4DJQD@85008|Micromonosporales	201174|Actinobacteria	KT	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
SRR25158416_k127_4004611_17	66869.JNXG01000008_gene1087	7.404e-50	186.0	COG5637@1|root,COG5637@2|Bacteria,2IN7X@201174|Actinobacteria,41CQ7@629295|Streptomyces griseus group	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_4004611_2	1122622.ATWJ01000014_gene490	1.286e-195	618.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4FG97@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_4016122_4	326424.FRAAL3887	5.934e-89	299.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria,4EX0W@85013|Frankiales	201174|Actinobacteria	T	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158416_k127_4016122_3	326424.FRAAL3886	5.142e-100	332.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158416_k127_4016122_13	67352.JODS01000048_gene3459	3.287e-09	64.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	2.4.1.187	ko:K04749,ko:K05946,ko:K06378	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003,ko03021	-	GT26	-	Glyco_tran_WecB,STAS,STAS_2
SRR25158416_k127_4016122_10	996637.SGM_4563	9.043e-17	86.0	COG2172@1|root,COG2172@2|Bacteria,2IQRD@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158416_k127_4016122_2	1120949.KB903350_gene8145	1.342e-111	380.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4D9IR@85008|Micromonosporales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158416_k127_4016122_9	1122622.ATWJ01000007_gene1774	1.92e-32	135.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4FHRE@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158416_k127_4016122_8	1211815.CBYP010000075_gene2954	1.913e-51	187.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,4EVK6@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_4016122_16	1304865.JAGF01000001_gene2174	3.149e-05	46.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158416_k127_4016122_5	196162.Noca_4965	5.88e-67	236.0	28PN6@1|root,2ZCB1@2|Bacteria,2INN5@201174|Actinobacteria,4DW3I@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158416_k127_4016122_14	446470.Snas_3453	2.658e-07	62.0	2E0MB@1|root,32W6J@2|Bacteria,2IR53@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4016122_1	1380347.JNII01000008_gene4335	2.911e-119	389.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4EUCJ@85013|Frankiales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_4016122_0	1132509.C447_12320	1.528e-135	438.0	COG0604@1|root,arCOG01458@2157|Archaea,2XV7H@28890|Euryarchaeota,23TUM@183963|Halobacteria	2157|Archaea	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158416_k127_4016122_7	269799.Gmet_1468	6.238e-58	219.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,4338I@68525|delta/epsilon subdivisions,2WXBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_4016122_11	1120983.KB894576_gene3431	1.535e-10	72.0	COG3595@1|root,COG3595@2|Bacteria,1QUNK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4016122_6	1429046.RR21198_1149	4.234e-64	226.0	2DZHZ@1|root,32VB7@2|Bacteria,2GPY2@201174|Actinobacteria,4FYYG@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4016122_15	1300345.LF41_2483	6.749e-07	59.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_4016122_12	1122138.AQUZ01000052_gene8412	2.181e-10	63.0	COG3576@1|root,COG3576@2|Bacteria,2I46F@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_4019196_5	367299.JOEE01000004_gene1371	1.633e-54	196.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4FGBX@85021|Intrasporangiaceae	201174|Actinobacteria	T	DNA-binding protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158416_k127_4019196_6	471852.Tcur_2912	3.168e-45	172.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4EJGE@85012|Streptosporangiales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158416_k127_4019196_1	1298880.AUEV01000007_gene4722	4.222e-147	480.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158416_k127_4019196_3	479432.Sros_2890	2.824e-66	238.0	COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,2IJ0D@201174|Actinobacteria,4EJRB@85012|Streptosporangiales	201174|Actinobacteria	E	Chorismate mutase type II	-	-	-	-	-	-	-	-	-	-	-	-	CM_2,DAHP_synth_1
SRR25158416_k127_4019196_0	1032480.MLP_28710	0.0	1670.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DN5X@85009|Propionibacteriales	201174|Actinobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158416_k127_4019196_7	1463864.JOGO01000003_gene1981	2.457e-11	74.0	2EGQJ@1|root,33AGQ@2|Bacteria,2IHWM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2567
SRR25158416_k127_4019196_4	1463900.JOIX01000040_gene2924	3.272e-57	203.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158416_k127_4019196_2	471852.Tcur_2897	7.716e-67	231.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4EHY2@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158416_k127_4026684_4	1231392.OCGS_0525	1.304e-102	336.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Methylmalonyl-CoA mutase	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158416_k127_4026684_11	269799.Gmet_0243	1.994e-25	123.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158416_k127_4026684_9	469383.Cwoe_3711	2.735e-54	200.0	COG0500@1|root,COG2226@2|Bacteria,2HNEB@201174|Actinobacteria,4CP8F@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_4026684_2	402881.Plav_1705	7.137e-118	389.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,1JN63@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158416_k127_4026684_1	365528.KB891219_gene967	2.505e-125	409.0	COG0500@1|root,COG2226@2|Bacteria,2H0T3@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_4026684_12	263358.VAB18032_23370	0.0006429	45.0	COG2242@1|root,COG2242@2|Bacteria,2IAR0@201174|Actinobacteria,4D9FM@85008|Micromonosporales	201174|Actinobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4026684_0	929712.KI912613_gene4227	2.637e-132	432.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4CPE1@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158416_k127_4026684_3	208439.AJAP_28385	1.016e-115	381.0	COG4122@1|root,COG4122@2|Bacteria,2IFBF@201174|Actinobacteria,4E30U@85010|Pseudonocardiales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158416_k127_4026684_10	1522072.IL54_2403	8.883e-27	126.0	COG2327@1|root,COG2327@2|Bacteria,1NT5N@1224|Proteobacteria,2UNUH@28211|Alphaproteobacteria,2KBK3@204457|Sphingomonadales	2|Bacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
SRR25158416_k127_4026684_5	710111.FraQA3DRAFT_3716	2.211e-101	355.0	COG0438@1|root,COG0438@2|Bacteria,2IJ4J@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_4026684_6	326424.FRAAL1237	4.643e-85	304.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ET5X@85013|Frankiales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158416_k127_4026684_7	479431.Namu_4205	1.082e-63	246.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4ESU0@85013|Frankiales	201174|Actinobacteria	GM	Transport permease protein	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_4026684_8	479431.Namu_4204	8.334e-56	198.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4ESAJ@85013|Frankiales	201174|Actinobacteria	GM	PFAM ABC transporter related	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158416_k127_4035401_4	1267533.KB906738_gene2027	3.648e-09	64.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158416_k127_4035401_2	1463864.JOGO01000173_gene1552	4.996e-96	325.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
SRR25158416_k127_4035401_3	710111.FraQA3DRAFT_1241	1.852e-09	71.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4ERIG@85013|Frankiales	201174|Actinobacteria	L	PFAM Transposase, Mutator	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SRR25158416_k127_4035401_1	298653.Franean1_3100	3.533e-107	360.0	COG3547@1|root,COG3547@2|Bacteria,2ID3X@201174|Actinobacteria,4EW6C@85013|Frankiales	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_4035401_0	1229780.BN381_580002	2.757e-134	432.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR25158416_k127_4035401_5	1313172.YM304_07150	8.589e-07	60.0	COG0596@1|root,COG0596@2|Bacteria,2I99I@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhaA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009410,GO:0009987,GO:0016020,GO:0016787,GO:0016824,GO:0018786,GO:0019120,GO:0030312,GO:0042178,GO:0042197,GO:0042206,GO:0042221,GO:0044237,GO:0044248,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:1901575	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158416_k127_4038420_6	227882.SAV_3744	1.114e-23	104.0	2EANA@1|root,334QU@2|Bacteria,2ISZY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4038420_5	935866.JAER01000039_gene617	5.191e-29	128.0	COG1525@1|root,COG1525@2|Bacteria,2IIR4@201174|Actinobacteria	201174|Actinobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
SRR25158416_k127_4038420_8	1079986.JH164874_gene2916	1.983e-10	65.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria	201174|Actinobacteria	L	nuclease	-	-	3.1.31.1	ko:K01174,ko:K07038	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158416_k127_4038420_1	862751.SACTE_5499	1.105e-98	325.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria	201174|Actinobacteria	K	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_4038420_4	285514.JNWO01000014_gene5689	4.236e-31	124.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria	201174|Actinobacteria	K	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_4038420_3	146922.JOFU01000022_gene4243	2.368e-52	190.0	COG1670@1|root,COG1670@2|Bacteria,2II7F@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158416_k127_4038420_2	258052.JNYV01000016_gene3297	8.832e-58	207.0	COG3554@1|root,COG3554@2|Bacteria,2INM2@201174|Actinobacteria,2M5VS@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4038420_0	1120950.KB892778_gene1035	2.423e-112	370.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4DP1Y@85009|Propionibacteriales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_4038420_7	1394178.AWOO02000016_gene6853	2.401e-20	94.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4EHTI@85012|Streptosporangiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158416_k127_4042047_6	1038859.AXAU01000003_gene6191	1.134e-09	65.0	2FGTF@1|root,348NS@2|Bacteria,1P2M9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4042047_1	1463917.JODC01000007_gene7258	2.114e-81	276.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_4042047_0	1380393.JHVP01000004_gene612	1.909e-224	716.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158416_k127_4042047_3	1048339.KB913029_gene4390	4.873e-51	193.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4042047_5	263358.VAB18032_11240	1.715e-37	145.0	COG3861@1|root,COG3861@2|Bacteria,2IQ4Y@201174|Actinobacteria,4DEHC@85008|Micromonosporales	201174|Actinobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4042047_4	1048339.KB913029_gene3678	6.925e-44	173.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158416_k127_4042047_2	477641.MODMU_5235	4.358e-61	214.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria,4ESUI@85013|Frankiales	201174|Actinobacteria	S	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158416_k127_4045246_0	1386089.N865_15190	3.712e-154	491.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4FEVC@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_4045246_1	1306990.BARG01000024_gene2703	6.859e-130	424.0	COG1052@1|root,COG1052@2|Bacteria,2I869@201174|Actinobacteria	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158416_k127_4054784_1	1077972.ARGLB_037_00790	2.069e-108	366.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2ITEV@201174|Actinobacteria,1WBN4@1268|Micrococcaceae	201174|Actinobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32,rve,rve_3
SRR25158416_k127_4054784_0	1032480.MLP_31970	7.344e-113	373.0	COG1834@1|root,COG1834@2|Bacteria,2GNTN@201174|Actinobacteria,4DNTR@85009|Propionibacteriales	201174|Actinobacteria	E	Amidinotransferase	ddaH	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
SRR25158416_k127_4054784_2	1121924.ATWH01000006_gene1982	7.918e-105	349.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4FTHA@85023|Microbacteriaceae	201174|Actinobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SRR25158416_k127_4054784_3	1121924.ATWH01000006_gene1983	4.365e-39	147.0	COG2963@1|root,COG2963@2|Bacteria,2GRDS@201174|Actinobacteria,4FT5E@85023|Microbacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158416_k127_4054784_4	1169152.AXVD01000049_gene882	3.433e-05	48.0	COG2801@1|root,COG2801@2|Bacteria,2HIF8@201174|Actinobacteria,4G3XF@85025|Nocardiaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158416_k127_4054784_5	102125.Xen7305DRAFT_00052620	0.0001621	46.0	COG0659@1|root,COG0659@2|Bacteria,1G0NU@1117|Cyanobacteria,3VI6K@52604|Pleurocapsales	1117|Cyanobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158416_k127_40717_7	1048339.KB913029_gene4284	5.655e-65	229.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158416_k127_40717_3	479432.Sros_8131	2.317e-131	441.0	2DNJB@1|root,32XT8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_40717_0	1123320.KB889576_gene1967	1.499e-154	509.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria	201174|Actinobacteria	J	3-5 exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158416_k127_40717_10	935866.JAER01000039_gene586	2.828e-55	199.0	2AIF4@1|root,318WM@2|Bacteria,2GK8R@201174|Actinobacteria,4DQE6@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3000
SRR25158416_k127_40717_2	585531.HMPREF0063_10542	3.359e-148	482.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,4DP2Q@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158416_k127_40717_4	1120950.KB892748_gene3252	2.885e-128	427.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4DNZH@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158416_k127_40717_5	1120950.KB892748_gene3253	1.548e-125	408.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4DP69@85009|Propionibacteriales	201174|Actinobacteria	S	Chlorite dismutase	cld	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158416_k127_40717_11	2045.KR76_23405	2.288e-53	197.0	COG2153@1|root,COG2153@2|Bacteria,2IFAM@201174|Actinobacteria,4DS8N@85009|Propionibacteriales	201174|Actinobacteria	F	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
SRR25158416_k127_40717_8	1033730.CAHG01000016_gene514	5.422e-59	208.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4DQU8@85009|Propionibacteriales	201174|Actinobacteria	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158416_k127_40717_13	1206737.BAGF01000035_gene1947	1.531e-37	147.0	COG2259@1|root,COG2259@2|Bacteria,2IMX8@201174|Actinobacteria,4G1GN@85025|Nocardiaceae	201174|Actinobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158416_k127_40717_1	101510.RHA1_ro05108	3.088e-149	479.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4FVXV@85025|Nocardiaceae	201174|Actinobacteria	L	DNA ligase	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158416_k127_40717_6	935866.JAER01000054_gene3076	3.588e-118	386.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158416_k127_40717_14	1210046.B277_03955	2.071e-25	108.0	2EF54@1|root,31TGM@2|Bacteria,2GYHP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_40717_12	106370.Francci3_1199	1.675e-47	188.0	COG0358@1|root,COG0358@2|Bacteria,2GSAF@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_40717_9	298653.Franean1_0264	6.248e-58	218.0	COG0358@1|root,COG0358@2|Bacteria,2GSAF@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_40717_15	247156.NFA_15200	1.504e-14	86.0	2CIEV@1|root,30ANG@2|Bacteria,2GVCG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
SRR25158416_k127_4078866_1	263358.VAB18032_00165	2.232e-43	177.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_4078866_0	1298880.AUEV01000005_gene900	1.354e-168	544.0	COG3408@1|root,COG3408@2|Bacteria,2ICEJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4094366_1	543632.JOJL01000054_gene221	5.38e-90	317.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158416_k127_4094366_5	1386089.N865_03270	1.353e-18	99.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2HEX2@201174|Actinobacteria,4FF31@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_4094366_2	1380390.JIAT01000011_gene2363	1.287e-40	158.0	2CA7I@1|root,30E5G@2|Bacteria,2IJ78@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4094366_4	208439.AJAP_05785	7.835e-29	119.0	COG3795@1|root,COG3795@2|Bacteria,2IIV2@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158416_k127_4094366_0	67373.JOBF01000013_gene4373	1.276e-164	530.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_4094366_3	656024.FsymDg_4035	4.12e-32	143.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4ET3J@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_4100652_9	1122138.AQUZ01000047_gene60	2.997e-22	101.0	2EH37@1|root,33AV6@2|Bacteria,2GQTI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4100652_7	1120950.KB892775_gene1170	7.804e-46	171.0	2F62G@1|root,33YKU@2|Bacteria,2IHNY@201174|Actinobacteria,4DRHE@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4100652_5	1120950.KB892775_gene1171	1.059e-76	267.0	COG3142@1|root,COG3142@2|Bacteria,2GKI8@201174|Actinobacteria,4DQWU@85009|Propionibacteriales	201174|Actinobacteria	P	CutC family	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
SRR25158416_k127_4100652_8	105420.BBPO01000006_gene2935	5.152e-35	140.0	COG4339@1|root,COG4339@2|Bacteria,2IQ60@201174|Actinobacteria,2NJHU@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF4031)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031
SRR25158416_k127_4100652_6	1206741.BAFX01000099_gene1050	9.666e-64	224.0	COG4339@1|root,COG4339@2|Bacteria,2GMYQ@201174|Actinobacteria,4G000@85025|Nocardiaceae	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031,HD
SRR25158416_k127_4100652_3	405948.SACE_6656	5.809e-139	453.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4E29D@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158416_k127_4100652_10	263358.VAB18032_12705	1.26e-11	67.0	295TY@1|root,2ZT51@2|Bacteria,2HC2W@201174|Actinobacteria,4DKPC@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4100652_1	1120950.KB892775_gene1176	1.449e-231	741.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DPFY@85009|Propionibacteriales	201174|Actinobacteria	L	AAA domain	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158416_k127_4100652_0	471852.Tcur_0810	2.398e-305	944.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4EHX6@85012|Streptosporangiales	201174|Actinobacteria	L	ERCC3/RAD25/XPB C-terminal helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR25158416_k127_4100652_2	1157637.KB892102_gene1559	2.306e-224	720.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
SRR25158416_k127_4100652_4	263358.VAB18032_25015	1.332e-96	331.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4DI6E@85008|Micromonosporales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158416_k127_4106072_5	1306174.JODP01000003_gene1849	5.03e-10	66.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158416_k127_4106072_3	1121939.L861_04700	1.025e-54	199.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1TC6K@1236|Gammaproteobacteria,1XPG2@135619|Oceanospirillales	135619|Oceanospirillales	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158416_k127_4106072_0	1146883.BLASA_4736	0.0	1011.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4ES3C@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158416_k127_4106072_1	1120949.KB903297_gene5433	8.196e-161	516.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria,4DB1Y@85008|Micromonosporales	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158416_k127_4106072_2	1463881.KL591016_gene5397	1.795e-143	466.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria	201174|Actinobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158416_k127_4106072_4	1352941.M877_07165	1.825e-24	107.0	COG0346@1|root,COG0346@2|Bacteria,2IHU2@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4115076_2	1380393.JHVP01000005_gene3710	1.11e-23	100.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria,4EUQ9@85013|Frankiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158416_k127_4115076_0	1123023.JIAI01000004_gene8155	1.202e-95	317.0	COG2334@1|root,COG2334@2|Bacteria,2GQ6F@201174|Actinobacteria,4E9MG@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158416_k127_4115076_1	591158.SSMG_00629	1.04e-82	283.0	COG3293@1|root,COG3293@2|Bacteria,2GMT0@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
SRR25158416_k127_4143614_1	450380.JPSY01000001_gene395	5.583e-28	115.0	COG3039@1|root,COG3039@2|Bacteria,2GJQM@201174|Actinobacteria	201174|Actinobacteria	L	Cluster 0025 8 SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158416_k127_4143614_2	1298863.AUEP01000001_gene720	5.504e-17	82.0	COG4270@1|root,COG4270@2|Bacteria,2GQJP@201174|Actinobacteria,4DS93@85009|Propionibacteriales	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158416_k127_4143614_0	1206744.BAGL01000045_gene1067	7.589e-157	497.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4G9MA@85025|Nocardiaceae	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	ko:K21209	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	Abhydrolase_6
SRR25158416_k127_4146899_6	58123.JOFJ01000001_gene3088	8.24e-66	227.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4EI63@85012|Streptosporangiales	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158416_k127_4146899_4	1157637.KB892092_gene6938	1.364e-116	387.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria	201174|Actinobacteria	M	Protein containing von Willebrand factor type A (VWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158416_k127_4146899_2	28444.JODQ01000001_gene2176	9.389e-158	507.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4EIDG@85012|Streptosporangiales	201174|Actinobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158416_k127_4146899_7	471852.Tcur_2977	1.14e-52	191.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4EJ8B@85012|Streptosporangiales	201174|Actinobacteria	S	MobA-like NTP transferase domain	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158416_k127_4146899_10	1137271.AZUM01000002_gene3036	7.819e-17	85.0	2EP16@1|root,33GN1@2|Bacteria,2IHWQ@201174|Actinobacteria,4E68S@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4146899_8	561175.KB894101_gene4552	2.889e-51	186.0	2BX7X@1|root,32RMD@2|Bacteria,2IKN7@201174|Actinobacteria,4EJM7@85012|Streptosporangiales	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4146899_0	1380370.JIBA01000016_gene722	1.083e-197	625.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria,4FF3V@85021|Intrasporangiaceae	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,DUF1116,Ligase_CoA
SRR25158416_k127_4146899_3	1123320.KB889640_gene4452	4.279e-142	474.0	COG0074@1|root,COG0074@2|Bacteria,2GN20@201174|Actinobacteria	201174|Actinobacteria	C	FdrA family	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
SRR25158416_k127_4146899_9	1156844.KB891849_gene3385	2.858e-25	116.0	2EIHP@1|root,33C91@2|Bacteria,2ICMY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
SRR25158416_k127_4146899_1	1123320.KB889640_gene4454	8.315e-182	592.0	COG2508@1|root,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria	201174|Actinobacteria	QT	transcriptional regulator	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRR25158416_k127_4146899_5	1123320.KB889640_gene4456	2.486e-83	283.0	COG1319@1|root,COG1319@2|Bacteria,2GP37@201174|Actinobacteria	201174|Actinobacteria	C	Molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158416_k127_4150254_2	1122609.AUGT01000006_gene1451	5.755e-56	201.0	COG2020@1|root,COG2020@2|Bacteria,2IT1A@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158416_k127_4150254_0	526225.Gobs_3547	8.377e-185	592.0	COG0596@1|root,COG0596@2|Bacteria,2IAVM@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_4150254_3	1246459.KB898374_gene3976	8.288e-41	166.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158416_k127_4150254_1	1150864.MILUP08_42675	7.194e-100	329.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4DB2V@85008|Micromonosporales	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_4150926_1	1229780.BN381_130124	6.014e-62	217.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,3UW6I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158416_k127_4150926_2	1869.MB27_04020	2.314e-42	162.0	2CHCP@1|root,32S5R@2|Bacteria,2IRB0@201174|Actinobacteria,4DEPC@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158416_k127_4150926_0	1120950.KB892810_gene7207	1.078e-109	361.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4DPJ5@85009|Propionibacteriales	201174|Actinobacteria	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158416_k127_4156606_3	196162.Noca_2251	5.642e-23	101.0	2FKWG@1|root,34CGS@2|Bacteria,2HAI5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4156606_1	1120956.JHZK01000007_gene2811	9.231e-45	166.0	COG0454@1|root,COG0456@2|Bacteria,1MZUT@1224|Proteobacteria,2UC9I@28211|Alphaproteobacteria,1JPAG@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_4156606_0	1394178.AWOO02000087_gene942	2.715e-156	505.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4EPS2@85012|Streptosporangiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_4156606_2	1122138.AQUZ01000001_gene1469	1.732e-28	114.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158416_k127_4160006_4	1048339.KB913029_gene4829	1.209e-164	559.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4ES7C@85013|Frankiales	201174|Actinobacteria	S	ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158416_k127_4160006_13	1120950.KB892765_gene5686	4.213e-42	166.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4DRFZ@85009|Propionibacteriales	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158416_k127_4160006_7	235985.BBPN01000007_gene3271	2.422e-97	326.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,2NFGN@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158416_k127_4160006_0	471853.Bcav_1730	0.0	1418.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158416_k127_4160006_9	68219.JNXI01000032_gene7010	1.887e-73	259.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria	201174|Actinobacteria	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158416_k127_4160006_2	479432.Sros_5845	3.926e-192	615.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4EG57@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	dldH5	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_4160006_10	749927.AMED_4206	8.534e-61	216.0	2B3JS@1|root,31W90@2|Bacteria,2GP1G@201174|Actinobacteria,4EBAP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4160006_12	1906.SFRA_14230	3.651e-45	183.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_4160006_11	994479.GL877878_gene1971	5.642e-54	195.0	COG0454@1|root,COG0454@2|Bacteria,2I32X@201174|Actinobacteria,4E4IA@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158416_k127_4160006_15	479432.Sros_6289	5.55e-31	124.0	2E4G6@1|root,32ZBB@2|Bacteria,2GR6E@201174|Actinobacteria,4EKH1@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4160006_6	479432.Sros_6290	3.656e-106	349.0	COG1018@1|root,COG1018@2|Bacteria,2I0Y9@201174|Actinobacteria,4EHIW@85012|Streptosporangiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRR25158416_k127_4160006_8	1123321.KB905817_gene5121	5.24e-79	268.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria	201174|Actinobacteria	M	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158416_k127_4160006_14	1283283.ATXA01000014_gene3614	1.611e-36	150.0	COG4291@1|root,COG4291@2|Bacteria,2IIVD@201174|Actinobacteria,4ETI9@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SRR25158416_k127_4160006_16	35754.JNYJ01000003_gene6395	2.533e-19	89.0	2A3JH@1|root,30S2I@2|Bacteria,2H133@201174|Actinobacteria,4DKYJ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4160006_5	1032480.MLP_04190	9.856e-133	434.0	COG2072@1|root,COG2072@2|Bacteria,2GMDH@201174|Actinobacteria,4DNVD@85009|Propionibacteriales	201174|Actinobacteria	C	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158416_k127_4160006_3	1121877.JQKF01000032_gene2046	1.109e-165	526.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4CNPH@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_4160006_1	1032480.MLP_04550	2e-323	1001.0	COG0366@1|root,COG0366@2|Bacteria,2GPF3@201174|Actinobacteria,4DTH6@85009|Propionibacteriales	201174|Actinobacteria	G	trehalose synthase	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
SRR25158416_k127_4160006_18	981369.JQMJ01000004_gene4776	0.0004679	46.0	COG2172@1|root,COG2172@2|Bacteria,2GWBZ@201174|Actinobacteria	201174|Actinobacteria	T	sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4160006_17	1208321.D104_05430	0.0001147	45.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,1S2JM@1236|Gammaproteobacteria,1XQ3K@135619|Oceanospirillales	135619|Oceanospirillales	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	F420_oxidored
SRR25158416_k127_4173416_2	1123024.AUII01000039_gene1428	3.598e-30	125.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,4E2J8@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4173416_3	110319.CF8_4194	1.257e-18	87.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4DV5C@85009|Propionibacteriales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158416_k127_4173416_0	1331060.RLDS_09320	1.727e-47	175.0	COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2TRE9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	-	-	-	ko:K21832	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158416_k127_4173416_1	1331060.RLDS_09320	1.827e-44	165.0	COG1018@1|root,COG1018@2|Bacteria,1MU6E@1224|Proteobacteria,2TRE9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	-	-	-	ko:K21832	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158416_k127_4176201_2	1283283.ATXA01000015_gene77	1.616e-92	312.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4EREZ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_4176201_3	298655.KI912266_gene1028	5.362e-62	222.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4EREZ@85013|Frankiales	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_4176201_1	526225.Gobs_2793	5.309e-148	477.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4EU93@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_4176201_5	1122138.AQUZ01000008_gene3701	1.474e-32	126.0	COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4DPKH@85009|Propionibacteriales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158416_k127_4176201_6	882086.SacxiDRAFT_3850	2.215e-22	104.0	COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4E279@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158416_k127_4176201_4	1122611.KB903985_gene3705	1.32e-37	148.0	COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4EIYE@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119,ko:K17328	ko02010,map02010	M00196,M00619	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.21,3.A.1.1.28	-	-	BPD_transp_1
SRR25158416_k127_4176201_0	1122611.KB903985_gene3708	4.578e-167	533.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4EFQV@85012|Streptosporangiales	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158416_k127_4179094_3	1120950.KB892746_gene3508	1.294e-34	134.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DPAI@85009|Propionibacteriales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158416_k127_4179094_0	1123237.Salmuc_01086	2.92e-106	366.0	COG0265@1|root,COG1864@1|root,COG0265@2|Bacteria,COG1864@2|Bacteria,1QSGF@1224|Proteobacteria,2TTI7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EF	DNA RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS,Trypsin_2
SRR25158416_k127_4179094_4	590998.Celf_3225	0.0009972	45.0	COG1864@1|root,COG1864@2|Bacteria,2IGAH@201174|Actinobacteria	201174|Actinobacteria	L	DNA RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
SRR25158416_k127_4179094_1	1121946.AUAX01000033_gene5692	1.111e-104	347.0	COG0627@1|root,COG0627@2|Bacteria,2GJX4@201174|Actinobacteria,4D9HJ@85008|Micromonosporales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158416_k127_4179094_2	1068980.ARVW01000001_gene4813	8.495e-74	250.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4EANK@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158416_k127_4186845_2	1121946.AUAX01000023_gene4169	4.488e-11	68.0	COG0596@1|root,COG0596@2|Bacteria,2I97G@201174|Actinobacteria,4D922@85008|Micromonosporales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_4186845_0	452652.KSE_10840	1.853e-83	287.0	COG3315@1|root,COG3315@2|Bacteria,2IF0D@201174|Actinobacteria	201174|Actinobacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
SRR25158416_k127_4186845_1	1380347.JNII01000005_gene3645	3.754e-28	123.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158416_k127_4186845_3	1298863.AUEP01000006_gene3210	2.823e-06	52.0	COG0262@1|root,COG0262@2|Bacteria,2GJU5@201174|Actinobacteria,4DUJC@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_4191447_7	1120950.KB892823_gene475	1.406e-17	84.0	2E6WZ@1|root,331GF@2|Bacteria,2I16Z@201174|Actinobacteria,4DVWK@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4191447_5	749414.SBI_08201	7.667e-57	204.0	COG1403@1|root,COG1403@2|Bacteria,2GMJV@201174|Actinobacteria	201174|Actinobacteria	V	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SRR25158416_k127_4191447_6	479435.Kfla_5393	1.744e-47	175.0	2CAW2@1|root,32RS7@2|Bacteria,2IB15@201174|Actinobacteria,4DRNV@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4191447_3	1122609.AUGT01000019_gene258	5.229e-130	430.0	COG0277@1|root,COG0277@2|Bacteria,2I40C@201174|Actinobacteria,4DTPY@85009|Propionibacteriales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_4191447_2	1120950.KB892823_gene471	1.037e-130	431.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4DPEQ@85009|Propionibacteriales	201174|Actinobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158416_k127_4191447_1	1209984.BN978_06461	1.086e-191	606.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,233J5@1762|Mycobacteriaceae	201174|Actinobacteria	E	diaminopimelate decarboxylase	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158416_k127_4191447_4	1209984.BN978_02624	3.91e-84	299.0	COG0589@1|root,COG0589@2|Bacteria,2I8XM@201174|Actinobacteria,2345H@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	uspA4	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158416_k127_4191447_0	1209984.BN978_02623	6.944e-217	682.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,23292@1762|Mycobacteriaceae	201174|Actinobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
SRR25158416_k127_4200115_10	469383.Cwoe_0858	7.696e-64	220.0	COG3795@1|root,COG3795@2|Bacteria,2IFD6@201174|Actinobacteria,4CSNW@84995|Rubrobacteria	84995|Rubrobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158416_k127_4200115_15	33876.JNXY01000033_gene2116	1.733e-20	104.0	28ND6@1|root,2ZBG0@2|Bacteria,2H5QC@201174|Actinobacteria,4DG7Q@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4200115_19	1056816.JAFQ01000004_gene1532	1.368e-11	70.0	COG4653@1|root,COG4653@2|Bacteria,2I9AZ@201174|Actinobacteria,4G006@85025|Nocardiaceae	201174|Actinobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SRR25158416_k127_4200115_13	1056816.JAFQ01000004_gene1532	1.941e-44	173.0	COG4653@1|root,COG4653@2|Bacteria,2I9AZ@201174|Actinobacteria,4G006@85025|Nocardiaceae	201174|Actinobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
SRR25158416_k127_4200115_20	1177928.TH2_04283	1.096e-07	60.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,2JPNJ@204441|Rhodospirillales	204441|Rhodospirillales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158416_k127_4200115_14	1121875.KB907551_gene1175	3.944e-26	112.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,1HZHR@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_4200115_22	1121017.AUFG01000012_gene1852	2.668e-05	51.0	COG3832@1|root,COG3832@2|Bacteria,2IBWM@201174|Actinobacteria,4FGG3@85021|Intrasporangiaceae	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4200115_7	926560.KE387026_gene4174	1.109e-88	302.0	COG1131@1|root,COG1131@2|Bacteria,1WI6M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_4200115_6	926560.KE387026_gene4175	8.458e-92	310.0	COG0842@1|root,COG0842@2|Bacteria,1WM4H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158416_k127_4200115_11	926560.KE387026_gene4176	1.469e-62	232.0	COG4585@1|root,COG4585@2|Bacteria,1WMI2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158416_k127_4200115_9	1211114.ALIP01000118_gene2083	4.304e-75	266.0	COG2197@1|root,COG2197@2|Bacteria,1R840@1224|Proteobacteria,1S0CT@1236|Gammaproteobacteria,1X3MU@135614|Xanthomonadales	135614|Xanthomonadales	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	YH67_01295	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158416_k127_4200115_4	1095767.CAHD01000033_gene1199	3.337e-105	348.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4F2GQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158416_k127_4200115_5	1394178.AWOO02000014_gene7733	2.764e-92	306.0	COG2227@1|root,COG2227@2|Bacteria,2HF1Q@201174|Actinobacteria,4EMG9@85012|Streptosporangiales	201174|Actinobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158416_k127_4200115_12	930171.Asphe3_23910	1.01e-47	177.0	COG3832@1|root,COG3832@2|Bacteria,2HK0N@201174|Actinobacteria,1WC5C@1268|Micrococcaceae	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4200115_16	930171.Asphe3_23910	3.109e-20	95.0	COG3832@1|root,COG3832@2|Bacteria,2HK0N@201174|Actinobacteria,1WC5C@1268|Micrococcaceae	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4200115_0	1385519.N801_14310	0.0	1546.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4FG5Q@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 32	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
SRR25158416_k127_4200115_18	1385518.N798_03815	1.504e-12	68.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4FG0D@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_4200115_17	1304865.JAGF01000001_gene2174	5.642e-14	75.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158416_k127_4200115_8	1122939.ATUD01000002_gene1481	4.899e-76	278.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4CQ63@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158416_k127_4200115_3	717774.Marme_3974	2.267e-111	371.0	COG1129@1|root,COG1129@2|Bacteria,1MVNR@1224|Proteobacteria,1RY9K@1236|Gammaproteobacteria,1XH5D@135619|Oceanospirillales	135619|Oceanospirillales	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K10554	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	ABC_tran
SRR25158416_k127_4200115_1	1463825.JNXC01000040_gene5119	1.563e-144	465.0	COG1172@1|root,COG1172@2|Bacteria,2GKAS@201174|Actinobacteria,4E0W0@85010|Pseudonocardiales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	frcC	-	-	ko:K10553	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	BPD_transp_2
SRR25158416_k127_4200115_2	1246448.ANAZ01000028_gene4498	3.26e-137	445.0	COG1879@1|root,COG1879@2|Bacteria,2HEHI@201174|Actinobacteria	201174|Actinobacteria	G	Periplasmic binding protein LacI transcriptional regulator	frcB	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
SRR25158416_k127_4204867_7	2074.JNYD01000046_gene7323	4.869e-06	49.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria,4E5XH@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158416_k127_4204867_3	479435.Kfla_6800	2.352e-132	428.0	COG2304@1|root,COG2304@2|Bacteria,2ICSY@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158416_k127_4204867_1	479435.Kfla_6801	1.083e-170	545.0	COG0631@1|root,COG0631@2|Bacteria,2GN60@201174|Actinobacteria	201174|Actinobacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
SRR25158416_k127_4204867_0	479435.Kfla_6802	8.914e-172	544.0	COG0515@1|root,COG0515@2|Bacteria,2GSJW@201174|Actinobacteria	201174|Actinobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158416_k127_4204867_2	1385520.N802_06510	4.869e-143	458.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2GN49@201174|Actinobacteria	201174|Actinobacteria	E	carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
SRR25158416_k127_4204867_5	1312959.KI914706_gene2960	2.09e-18	95.0	COG5416@1|root,COG5416@2|Bacteria	2|Bacteria	FG	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
SRR25158416_k127_4204867_4	1380356.JNIK01000017_gene2932	2.419e-35	142.0	2C0X2@1|root,34BB8@2|Bacteria,2H7C4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4204867_6	1246474.ANBE01000038_gene4285	9.111e-14	71.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4EGT1@85012|Streptosporangiales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158416_k127_4222852_42	1114959.SZMC14600_08654	4.975e-23	105.0	COG1309@1|root,COG1309@2|Bacteria,2GUDI@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_4222852_38	35754.JNYJ01000005_gene5489	6.378e-36	141.0	2CNK3@1|root,32SH9@2|Bacteria,2IRH1@201174|Actinobacteria,4DEV8@85008|Micromonosporales	201174|Actinobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
SRR25158416_k127_4222852_40	1229203.KI301992_gene2141	2.607e-26	109.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158416_k127_4222852_37	882082.SaccyDRAFT_0450	8.486e-38	149.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4E3JC@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the UPF0336 family	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158416_k127_4222852_30	1380356.JNIK01000018_gene684	7.19e-49	180.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4ESZ9@85013|Frankiales	201174|Actinobacteria	I	PFAM MaoC domain protein dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158416_k127_4222852_11	644283.Micau_3520	5.938e-106	357.0	COG0738@1|root,COG0738@2|Bacteria,2I3KY@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_4222852_8	196162.Noca_0672	3.099e-128	439.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4DNF7@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158416_k127_4222852_6	1122138.AQUZ01000015_gene6805	3.873e-157	508.0	COG1816@1|root,COG1816@2|Bacteria,2GKJP@201174|Actinobacteria,4DN6T@85009|Propionibacteriales	201174|Actinobacteria	F	adenosine deaminase	add	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158416_k127_4222852_5	1048339.KB913029_gene2726	6.405e-201	632.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4ES0T@85013|Frankiales	201174|Actinobacteria	E	aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158416_k127_4222852_45	207954.MED92_04552	5.98e-05	46.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales	135619|Oceanospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158416_k127_4222852_43	1120950.KB892746_gene3583	1.045e-21	99.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4DSA3@85009|Propionibacteriales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158416_k127_4222852_15	1120950.KB892746_gene3584	3.978e-91	307.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4DPR5@85009|Propionibacteriales	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158416_k127_4222852_20	1223523.H340_07913	5.818e-75	253.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158416_k127_4222852_10	1352941.M877_15660	2.484e-115	375.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158416_k127_4222852_22	1120950.KB892746_gene3590	2.596e-68	237.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4DQF9@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158416_k127_4222852_28	1380356.JNIK01000018_gene678	1.731e-56	201.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4ESPE@85013|Frankiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158416_k127_4222852_1	1048339.KB913029_gene2735	0.0	1973.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4ES8S@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158416_k127_4222852_0	1048339.KB913029_gene2736	0.0	2083.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4ERS7@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158416_k127_4222852_23	471852.Tcur_4326	8.296e-66	229.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4EJ9N@85012|Streptosporangiales	201174|Actinobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158416_k127_4222852_18	1184607.AUCHE_08_03390	3.491e-83	285.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4F6CR@85018|Dermatophilaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158416_k127_4222852_2	1048339.KB913029_gene2747	0.0	1172.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4ERUQ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158416_k127_4222852_3	543632.JOJL01000008_gene5716	2.667e-226	715.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4DBW2@85008|Micromonosporales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158416_k127_4222852_27	1048339.KB913029_gene2749	1.455e-58	209.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4ESVR@85013|Frankiales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158416_k127_4222852_12	1210046.B277_02376	3.601e-105	344.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4FECG@85021|Intrasporangiaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158416_k127_4222852_16	1454010.JEOE01000021_gene2558	9.332e-86	304.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4F0Z8@85016|Cellulomonadaceae	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158416_k127_4222852_31	1120954.ATXE01000003_gene354	6.09e-47	171.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4DR9N@85009|Propionibacteriales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158416_k127_4222852_7	590998.Celf_1004	8.979e-155	491.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4F110@85016|Cellulomonadaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158416_k127_4222852_29	1048339.KB913029_gene2754	9.673e-52	183.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4ESWC@85013|Frankiales	201174|Actinobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158416_k127_4222852_32	1122611.KB903951_gene6333	3.279e-44	164.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4EJCM@85012|Streptosporangiales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158416_k127_4222852_9	1184607.AUCHE_08_03500	1.378e-117	386.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4F6F5@85018|Dermatophilaceae	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158416_k127_4222852_19	1380346.JNIH01000003_gene2048	9.648e-79	265.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria	201174|Actinobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158416_k127_4222852_41	1184607.AUCHE_08_03520	6.636e-25	108.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4F76H@85018|Dermatophilaceae	201174|Actinobacteria	J	Ribosomal L29 protein	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158416_k127_4222852_33	1133850.SHJG_5806	3.359e-43	160.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158416_k127_4222852_21	1150864.MILUP08_46307	8.023e-69	236.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4DDMH@85008|Micromonosporales	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158416_k127_4222852_35	1288079.AUKN01000012_gene714	9.621e-40	151.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria	201174|Actinobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158416_k127_4222852_14	1123320.KB889574_gene5562	4.318e-98	324.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158416_k127_4222852_39	743718.Isova_0670	1.618e-33	130.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4F4WT@85017|Promicromonosporaceae	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158416_k127_4222852_24	227882.SAV_4940	3.358e-63	223.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158416_k127_4222852_17	1123065.ATWL01000003_gene900	5.829e-84	281.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158416_k127_4222852_34	1380354.JIAN01000005_gene1436	4.344e-42	159.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4F2HV@85016|Cellulomonadaceae	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158416_k127_4222852_13	1449355.JQNR01000005_gene3721	1.289e-100	333.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158416_k127_4222852_44	351607.Acel_0324	4.475e-19	94.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4ETGZ@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158416_k127_4222852_26	1032480.MLP_11170	1.128e-61	216.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4DQND@85009|Propionibacteriales	201174|Actinobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158416_k127_4222852_36	1032480.MLP_05200	1.065e-39	152.0	COG1525@1|root,COG1525@2|Bacteria,2HQMW@201174|Actinobacteria,4DW9B@85009|Propionibacteriales	201174|Actinobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4222852_4	1122609.AUGT01000009_gene3432	1.393e-202	640.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4DN3Y@85009|Propionibacteriales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158416_k127_4222852_25	935866.JAER01000028_gene1514	3.728e-63	228.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4DP2T@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158416_k127_4255342_2	1298880.AUEV01000002_gene1434	1.657e-127	415.0	COG0492@1|root,COG0492@2|Bacteria,2GJ1Z@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin-NADP reductase	-	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158416_k127_4255342_1	685727.REQ_25530	1.425e-167	543.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4FVWF@85025|Nocardiaceae	201174|Actinobacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, FAD binding, electron transport and carotenoid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158416_k127_4255342_8	479435.Kfla_1541	8.576e-56	201.0	COG5592@1|root,COG5592@2|Bacteria,2IJ0S@201174|Actinobacteria,4DRFS@85009|Propionibacteriales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Rho_N
SRR25158416_k127_4255342_3	935866.JAER01000050_gene879	2.564e-117	387.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4DN9S@85009|Propionibacteriales	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158416_k127_4255342_9	1229780.BN381_40041	4.379e-50	185.0	2CK3K@1|root,32SBH@2|Bacteria,2IQJH@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Ion	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158416_k127_4255342_6	710686.Mycsm_06300	3.254e-57	200.0	2BARS@1|root,3246W@2|Bacteria,2IM0H@201174|Actinobacteria,23ABR@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4255342_11	1385520.N802_10410	8.292e-18	85.0	COG3360@1|root,COG3360@2|Bacteria,2ISR4@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158416_k127_4255342_10	391625.PPSIR1_08317	3.405e-18	95.0	COG4195@1|root,COG4195@2|Bacteria,1QATJ@1224|Proteobacteria,435AK@68525|delta/epsilon subdivisions,2WZMP@28221|Deltaproteobacteria,2Z2DU@29|Myxococcales	28221|Deltaproteobacteria	S	phage-related replication protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_4255342_5	1206732.BAGD01000020_gene298	2.722e-63	219.0	COG5649@1|root,COG5649@2|Bacteria,2IHVG@201174|Actinobacteria,4G1W6@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158416_k127_4255342_0	35754.JNYJ01000022_gene8153	5.917e-198	627.0	COG0277@1|root,COG0277@2|Bacteria,2IGII@201174|Actinobacteria,4DM0N@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_4255342_7	1037409.BJ6T_23800	1.287e-56	206.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR25158416_k127_4255342_4	479435.Kfla_4207	3.48e-70	241.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,Cupin_7
SRR25158416_k127_4255342_12	1211815.CBYP010000012_gene472	6.702e-05	53.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158416_k127_42574_2	1394178.AWOO02000053_gene8133	0.0	1073.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4EFGN@85012|Streptosporangiales	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158416_k127_42574_13	1095767.CAHD01000100_gene1501	9.001e-65	231.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4F1GK@85016|Cellulomonadaceae	201174|Actinobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRR25158416_k127_42574_3	1120950.KB892707_gene4731	1.325e-255	792.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4DNNP@85009|Propionibacteriales	201174|Actinobacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158416_k127_42574_4	1122138.AQUZ01000012_gene6098	2.958e-243	781.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4DWPC@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158416_k127_42574_17	604331.AUHY01000022_gene1541	1.442e-45	173.0	COG0580@1|root,COG0580@2|Bacteria,1WKA2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158416_k127_42574_6	35754.JNYJ01000030_gene7622	9.003e-116	379.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4DBBA@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158416_k127_42574_28	1229203.KI301992_gene713	2.025e-09	60.0	2EHMB@1|root,335MH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_42574_5	58123.JOFJ01000001_gene3231	1.817e-135	446.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria,4EFWI@85012|Streptosporangiales	201174|Actinobacteria	J	Metallopeptidase family M24	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158416_k127_42574_15	1380354.JIAN01000005_gene1236	1.093e-56	205.0	COG2138@1|root,COG2138@2|Bacteria,2GNJ0@201174|Actinobacteria,4F18A@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM cobalamin (vitamin B12) biosynthesis CbiX protein	sirB	-	-	-	-	-	-	-	-	-	-	-	CbiX
SRR25158416_k127_42574_8	1123023.JIAI01000005_gene822	1.473e-86	295.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4E0WG@85010|Pseudonocardiales	201174|Actinobacteria	GK	Transcriptional regulator sugar kinase	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158416_k127_42574_26	101510.RHA1_ro01178	2.097e-13	75.0	2AR1Y@1|root,31GAW@2|Bacteria,2HK0E@201174|Actinobacteria,4G7PU@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_42574_7	134676.ACPL_657	7.938e-98	336.0	COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria,4DBCJ@85008|Micromonosporales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
SRR25158416_k127_42574_16	1192034.CAP_7447	1.427e-53	196.0	COG0500@1|root,COG2226@2|Bacteria,1RJDW@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_25
SRR25158416_k127_42574_18	479431.Namu_1755	4.076e-41	155.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria,4EV7U@85013|Frankiales	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158416_k127_42574_23	994479.GL877878_gene44	1.012e-16	93.0	COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_42574_14	1210046.B277_11270	3.784e-63	228.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4FG2P@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_42574_19	1283283.ATXA01000001_gene642	9.867e-40	159.0	COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4EWMZ@85013|Frankiales	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
SRR25158416_k127_42574_32	566552.BIFCAT_00876	0.0009684	46.0	COG4626@1|root,COG4626@2|Bacteria,2IB7D@201174|Actinobacteria,4CZEW@85004|Bifidobacteriales	201174|Actinobacteria	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
SRR25158416_k127_42574_25	479433.Caci_5508	7.195e-14	82.0	2C4NE@1|root,32RE9@2|Bacteria,2IGDU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4209
SRR25158416_k127_42574_12	930171.Asphe3_31150	4.265e-66	231.0	COG1145@1|root,32SB1@2|Bacteria,2IJFQ@201174|Actinobacteria,1W9BP@1268|Micrococcaceae	201174|Actinobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
SRR25158416_k127_42574_0	1157943.KB892706_gene4127	0.0	1170.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,2344K@1762|Mycobacteriaceae	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158416_k127_42574_1	479431.Namu_1742	0.0	1088.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4ERMQ@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158416_k127_42574_22	446466.Cfla_3668	2.845e-20	92.0	COG2608@1|root,COG2608@2|Bacteria,2I1G3@201174|Actinobacteria,4F1KP@85016|Cellulomonadaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
SRR25158416_k127_42574_20	266940.Krad_0784	1.244e-37	143.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158416_k127_42574_29	110319.CF8_1312	5.825e-06	50.0	COG4447@1|root,COG4447@2|Bacteria,2GN53@201174|Actinobacteria,4DRB6@85009|Propionibacteriales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158416_k127_42574_11	928724.SacglDRAFT_02943	5.887e-67	231.0	COG1018@1|root,COG1018@2|Bacteria,2IN34@201174|Actinobacteria,4E4YQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_42574_10	1289387.AUKW01000023_gene3046	1.5e-73	252.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158416_k127_42574_24	1223543.GP2_003_01050	1.032e-15	83.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_42574_21	477641.MODMU_2527	5.128e-34	136.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158416_k127_42574_9	1463917.JODC01000007_gene7258	3.81e-83	282.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_4287140_3	1172181.KB911726_gene1781	2e-07	52.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
SRR25158416_k127_4287140_0	595593.JREV01000008_gene2811	9.047e-133	434.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,1WAF9@1268|Micrococcaceae	201174|Actinobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
SRR25158416_k127_4287140_2	494419.ALPM01000124_gene1367	1.197e-40	153.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria,1WA0T@1268|Micrococcaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158416_k127_4287140_1	526225.Gobs_4237	2.919e-127	420.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria,4ERQ4@85013|Frankiales	201174|Actinobacteria	S	PFAM Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158416_k127_46039_6	298655.KI912267_gene7735	1.33e-46	170.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,4ESKA@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158416_k127_46039_5	35754.JNYJ01000009_gene1872	1.444e-79	278.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria,4DIN7@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158416_k127_46039_0	35754.JNYJ01000009_gene1873	8.221e-290	913.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DB3M@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158416_k127_46039_3	543632.JOJL01000005_gene4796	4.223e-105	350.0	COG0454@1|root,COG0456@2|Bacteria,2H9F9@201174|Actinobacteria	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_46039_1	479434.Sthe_1229	6.71e-178	572.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_46039_7	930171.Asphe3_27240	2.268e-31	128.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_46039_2	290399.Arth_2883	2.359e-134	437.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria	201174|Actinobacteria	P	oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158416_k127_46039_4	1120949.KB903328_gene8838	7.383e-84	281.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_46039_8	37919.EP51_03910	0.0001409	46.0	29VND@1|root,30H5P@2|Bacteria,2IG0Q@201174|Actinobacteria,4G95E@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_465625_0	405948.SACE_4257	5.235e-234	735.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4DX7R@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Alpha amylase, catalytic	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158416_k127_465625_1	743718.Isova_1062	1.007e-56	202.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4F4FZ@85017|Promicromonosporaceae	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158416_k127_465625_2	1394178.AWOO02000010_gene4046	1.254e-54	199.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4EIRU@85012|Streptosporangiales	201174|Actinobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158416_k127_465625_3	656024.FsymDg_1487	7.392e-12	66.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4ES6X@85013|Frankiales	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158416_k127_474225_5	1463821.JOGR01000001_gene1503	1.847e-72	251.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158416_k127_474225_0	1463821.JOGR01000001_gene1504	7.576e-129	420.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4EZ5G@85014|Glycomycetales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_474225_9	42256.RradSPS_0363	9.167e-21	95.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4CRP7@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2
SRR25158416_k127_474225_1	1132509.C447_12320	3.36e-119	388.0	COG0604@1|root,arCOG01458@2157|Archaea,2XV7H@28890|Euryarchaeota,23TUM@183963|Halobacteria	2157|Archaea	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158416_k127_474225_4	1380347.JNII01000006_gene1565	2.987e-90	302.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EU8Z@85013|Frankiales	201174|Actinobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_474225_6	479435.Kfla_2451	2.601e-72	260.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4DUSB@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_474225_3	446469.Sked_29920	5.453e-107	360.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158416_k127_474225_2	1150864.MILUP08_45901	1.049e-116	383.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DBQV@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_474225_8	136273.GY22_04940	2.997e-46	176.0	COG0596@1|root,COG0596@2|Bacteria,2IDI0@201174|Actinobacteria,1WABF@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_474225_7	1304865.JAGF01000001_gene2388	3.138e-60	211.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4F0J1@85016|Cellulomonadaceae	201174|Actinobacteria	E	Amino acid permease	ydaO	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158416_k127_484057_1	1120950.KB892715_gene2451	3.092e-76	263.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4DQWR@85009|Propionibacteriales	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158416_k127_484057_3	1120950.KB892715_gene2452	1.674e-69	254.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4DPWU@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidase family M23	pdc2	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158416_k127_484057_2	446468.Ndas_3721	5.992e-71	243.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4EJ2F@85012|Streptosporangiales	201174|Actinobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158416_k127_484057_0	1122138.AQUZ01000038_gene7968	2.624e-134	434.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria,4DTAF@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
SRR25158416_k127_486203_5	67315.JOBD01000020_gene7430	6.046e-49	190.0	COG1280@1|root,COG1280@2|Bacteria,2IPDI@201174|Actinobacteria	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158416_k127_486203_1	1192124.LIG30_4795	8.432e-102	339.0	COG0596@1|root,COG0596@2|Bacteria,1R584@1224|Proteobacteria,2VPZ4@28216|Betaproteobacteria,1K4Z9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_486203_4	1077972.ARGLB_094_00310	4.577e-65	229.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
SRR25158416_k127_486203_2	140110.NechaP95209	8.721e-89	309.0	COG0684@1|root,2S3HG@2759|Eukaryota,38DZT@33154|Opisthokonta,3P04V@4751|Fungi,3QK5C@4890|Ascomycota,21517@147550|Sordariomycetes,3THKM@5125|Hypocreales,1FTIT@110618|Nectriaceae	4751|Fungi	H	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158416_k127_486203_3	1370125.AUWT01000028_gene5069	1.117e-87	298.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,2331B@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158416_k127_486203_0	1206725.BAFU01000170_gene1890	3.27e-129	415.0	COG2801@1|root,COG2801@2|Bacteria,2HIF8@201174|Actinobacteria,4G3XF@85025|Nocardiaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158416_k127_492503_3	1179773.BN6_24550	1.023e-08	56.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4DY9W@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158416_k127_492503_0	1150864.MILUP08_42675	2.55e-89	304.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4DB2V@85008|Micromonosporales	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_492503_1	1146883.BLASA_1000	3.436e-28	113.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4ERKI@85013|Frankiales	201174|Actinobacteria	U	type II secretion system protein E	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158416_k127_492732_5	1179773.BN6_24550	1.023e-08	56.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4DY9W@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158416_k127_492732_4	1125973.JNLC01000015_gene3335	3.761e-13	78.0	COG2020@1|root,COG2020@2|Bacteria,1R47K@1224|Proteobacteria,2VG20@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
SRR25158416_k127_492732_3	1211815.CBYP010000020_gene1750	2.917e-17	83.0	2EGSG@1|root,33AIJ@2|Bacteria,2GWW3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
SRR25158416_k127_492732_1	1380370.JIBA01000018_gene534	1.357e-89	297.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4FH86@85021|Intrasporangiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158416_k127_492732_0	1089544.KB912942_gene3244	2.093e-95	319.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ3@201174|Actinobacteria,4DX70@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_492732_2	994479.GL877879_gene5722	1.109e-78	275.0	COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria,4DX4R@85010|Pseudonocardiales	201174|Actinobacteria	CG	lipid glycosylation	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_transf_28,UDPGT
SRR25158416_k127_492732_6	1246995.AFR_23425	3.456e-07	62.0	COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria,4DBQP@85008|Micromonosporales	201174|Actinobacteria	CG	glycosyl	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
SRR25158416_k127_494160_6	269800.Tfu_2694	5.849e-20	93.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4EHQT@85012|Streptosporangiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158416_k127_494160_4	68570.DC74_3888	1.381e-62	216.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158416_k127_494160_1	58123.JOFJ01000002_gene2626	3.301e-186	591.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4EHRB@85012|Streptosporangiales	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRR25158416_k127_494160_3	1288079.AUKN01000016_gene224	3.186e-112	366.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158416_k127_494160_0	1464048.JNZS01000016_gene3951	1.222e-266	834.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2GN49@201174|Actinobacteria,4DANI@85008|Micromonosporales	201174|Actinobacteria	M	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
SRR25158416_k127_494160_2	391037.Sare_1701	4.489e-159	518.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2GN49@201174|Actinobacteria,4DANI@85008|Micromonosporales	201174|Actinobacteria	M	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
SRR25158416_k127_494160_5	1095767.CAHD01000126_gene1207	3.298e-30	126.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4F0VS@85016|Cellulomonadaceae	201174|Actinobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158416_k127_495606_1	58123.JOFJ01000004_gene1730	2.309e-118	386.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4EH1C@85012|Streptosporangiales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158416_k127_495606_2	2002.JOEQ01000007_gene2065	5.289e-96	322.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4EG2D@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158416_k127_495606_5	1120950.KB892760_gene5715	8.403e-49	186.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4DRF9@85009|Propionibacteriales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158416_k127_495606_4	1121946.AUAX01000003_gene1454	8.624e-63	220.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4DDD4@85008|Micromonosporales	201174|Actinobacteria	I	B12 binding domain	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158416_k127_495606_0	1380356.JNIK01000018_gene570	9.425e-174	554.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4ES6Z@85013|Frankiales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158416_k127_495606_3	1236902.ANAS01000059_gene3117	6.123e-89	300.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4EGE1@85012|Streptosporangiales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158416_k127_502649_30	436229.JOEH01000009_gene4564	1.965e-05	48.0	COG1609@1|root,COG1609@2|Bacteria,2GSWK@201174|Actinobacteria,2NJKA@228398|Streptacidiphilus	201174|Actinobacteria	K	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_502649_23	1306174.JODP01000003_gene1881	1.567e-55	197.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158416_k127_502649_25	37919.EP51_11240	6.817e-50	182.0	COG3759@1|root,COG3759@2|Bacteria,2GVKG@201174|Actinobacteria,4G1WK@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
SRR25158416_k127_502649_2	1463856.JOHY01000043_gene7260	1.78e-212	669.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria	201174|Actinobacteria	F	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158416_k127_502649_24	1449353.JQMQ01000005_gene1439	3.894e-54	201.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158416_k127_502649_18	1454010.JEOE01000001_gene728	4.171e-74	257.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4F0T2@85016|Cellulomonadaceae	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158416_k127_502649_11	1123320.KB889701_gene9186	2.233e-100	339.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158416_k127_502649_27	1121946.AUAX01000004_gene936	6.116e-43	171.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria	201174|Actinobacteria	E	Chorismate mutase	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158416_k127_502649_14	882082.SaccyDRAFT_3384	8.889e-97	324.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DXJJ@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158416_k127_502649_17	1122611.KB904029_gene5405	1.107e-75	257.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4EG7D@85012|Streptosporangiales	201174|Actinobacteria	K	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158416_k127_502649_15	1048339.KB913029_gene4083	1.015e-93	316.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4ERDV@85013|Frankiales	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158416_k127_502649_6	1048339.KB913029_gene4082	9.602e-133	429.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4ERYA@85013|Frankiales	201174|Actinobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158416_k127_502649_5	1120950.KB892767_gene5149	5.803e-140	452.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4DNSC@85009|Propionibacteriales	201174|Actinobacteria	L	tyrosine recombinase	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_502649_3	219305.MCAG_04961	9.432e-185	587.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4DA3S@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158416_k127_502649_26	446466.Cfla_0488	3.588e-45	174.0	2DF72@1|root,32U4U@2|Bacteria,2GIV4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_502649_16	1120950.KB892767_gene5173	3.374e-83	287.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4DR6U@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158416_k127_502649_0	479435.Kfla_5413	2.667e-290	905.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4DP71@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1699	CTP_synth_N,GATase
SRR25158416_k127_502649_12	263358.VAB18032_15405	1.046e-98	341.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4D9E0@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_502649_8	1123320.KB889701_gene9163	3.288e-114	387.0	COG0728@1|root,COG0728@2|Bacteria,2GKWW@201174|Actinobacteria	201174|Actinobacteria	M	virulence factor MVIN family protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158416_k127_502649_19	28444.JODQ01000004_gene6102	1.69e-66	241.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4EG6C@85012|Streptosporangiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_502649_22	1120950.KB892767_gene5180	1.13e-56	211.0	2D1T0@1|root,32TBA@2|Bacteria,2I8E5@201174|Actinobacteria,4DRW3@85009|Propionibacteriales	201174|Actinobacteria	S	Copper transport outer membrane protein, MctB	mctB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796	-	-	-	-	-	-	-	-	-	-	MctB
SRR25158416_k127_502649_4	1380393.JHVP01000009_gene1292	1.194e-165	532.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4ERVF@85013|Frankiales	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR25158416_k127_502649_1	1123320.KB889589_gene4239	9.118e-214	690.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158416_k127_502649_7	67352.JODS01000021_gene3775	2.146e-123	406.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158416_k127_502649_10	1123320.KB889589_gene4237	5.779e-102	342.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria	201174|Actinobacteria	J	Ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158416_k127_502649_13	105425.BBPL01000084_gene4905	1.411e-98	339.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,2NEG9@228398|Streptacidiphilus	201174|Actinobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158416_k127_502649_9	298654.FraEuI1c_1723	2.23e-103	351.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158416_k127_502649_28	1122609.AUGT01000002_gene4060	2.056e-25	111.0	COG0629@1|root,COG0629@2|Bacteria,2GRPQ@201174|Actinobacteria,4DSF0@85009|Propionibacteriales	201174|Actinobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158416_k127_502649_20	1048339.KB913029_gene3275	1.532e-65	235.0	COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4ESUY@85013|Frankiales	201174|Actinobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158416_k127_502649_21	566461.SSFG_03805	2.938e-62	214.0	2AU0F@1|root,31JKB@2|Bacteria,2IT83@201174|Actinobacteria	201174|Actinobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_505450_16	351607.Acel_0439	1.547e-12	78.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4ESZY@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158416_k127_505450_11	1463821.JOGR01000001_gene1602	2.141e-51	193.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158416_k127_505450_10	1120936.KB907208_gene647	4.955e-60	224.0	COG0438@1|root,COG0438@2|Bacteria,2GX8V@201174|Actinobacteria,4EG9S@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_505450_9	1217720.ALOX01000053_gene1578	3.038e-65	238.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.187	ko:K00563,ko:K07112	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_23
SRR25158416_k127_505450_17	408672.NBCG_05657	7.494e-07	62.0	2DS2E@1|root,33E7M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT
SRR25158416_k127_505450_14	743836.AYNA01000126_gene1371	3.89e-26	127.0	COG0500@1|root,COG2226@2|Bacteria,1N2N4@1224|Proteobacteria,2UDEU@28211|Alphaproteobacteria,370RC@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_505450_12	543728.Vapar_0760	2.715e-31	144.0	COG0438@1|root,COG0438@2|Bacteria,1Q8Z0@1224|Proteobacteria,2W01K@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158416_k127_505450_0	292.DM42_948	5.431e-153	512.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1QTZD@1224|Proteobacteria,2VPU0@28216|Betaproteobacteria,1K7DE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158416_k127_505450_8	292.DM42_949	5.795e-69	245.0	COG4627@1|root,COG4627@2|Bacteria,1PDQR@1224|Proteobacteria,2W33A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_505450_4	1229780.BN381_10122	9.168e-122	406.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,3UWNE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	ATPases associated with a variety of cellular activities	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158416_k127_505450_6	1229780.BN381_10123	5.239e-73	256.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,3UXK0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	ABC-2 type transporter	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_505450_15	292.DM42_947	1.048e-24	118.0	COG4424@1|root,COG4424@2|Bacteria,1Q0AJ@1224|Proteobacteria,2W527@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Stf0 sulphotransferase	-	-	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
SRR25158416_k127_505450_13	436229.JOEH01000009_gene4709	7.168e-28	119.0	COG0438@1|root,COG0438@2|Bacteria,2IA6D@201174|Actinobacteria,2NKZP@228398|Streptacidiphilus	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR25158416_k127_505450_1	469383.Cwoe_3710	5.265e-144	464.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4CPE1@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158416_k127_505450_7	525909.Afer_0742	3.2e-71	256.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4CN35@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_505450_5	1211815.CBYP010000044_gene383	1.127e-80	281.0	COG1196@1|root,COG1196@2|Bacteria,2HVYZ@201174|Actinobacteria,4EW9J@85013|Frankiales	201174|Actinobacteria	D	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158416_k127_505450_3	1211815.CBYP010000044_gene384	4.723e-127	422.0	COG0438@1|root,COG0438@2|Bacteria,2H1Y6@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158416_k127_505450_2	1123052.AUDF01000005_gene995	6.68e-135	448.0	COG0438@1|root,COG0438@2|Bacteria,2GVCY@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158416_k127_508089_0	1120950.KB892716_gene2447	5.04e-175	552.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4DN44@85009|Propionibacteriales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158416_k127_508089_2	935866.JAER01000019_gene3971	3.808e-76	263.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4DQTE@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158416_k127_508089_3	1184609.KILIM_022_00440	2.172e-75	260.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4F6U0@85018|Dermatophilaceae	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158416_k127_508089_1	1120950.KB892782_gene269	6.417e-97	322.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DN90@85009|Propionibacteriales	201174|Actinobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158416_k127_508089_4	1206733.BAGC01000040_gene1690	5.473e-16	85.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4FX6B@85025|Nocardiaceae	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_516532_2	446466.Cfla_0194	7.667e-27	117.0	COG1595@1|root,COG1595@2|Bacteria,2IRNG@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_516532_0	67315.JOBD01000002_gene2906	7.774e-74	260.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158416_k127_516532_1	67315.JOBD01000002_gene2904	3.056e-30	126.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158416_k127_526051_7	1150398.JIBJ01000011_gene2308	1.017e-14	76.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_526051_6	1246995.AFR_42035	8.32e-44	164.0	COG0645@1|root,COG0645@2|Bacteria,2IM2M@201174|Actinobacteria,4DEAY@85008|Micromonosporales	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158416_k127_526051_4	1283283.ATXA01000005_gene2208	5.215e-81	279.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4EWWQ@85013|Frankiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158416_k127_526051_3	479435.Kfla_3194	1.251e-85	291.0	COG1357@1|root,COG1357@2|Bacteria,2GN74@201174|Actinobacteria	201174|Actinobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158416_k127_526051_9	545695.TREAZ_2050	7.63e-07	55.0	2C530@1|root,2ZRHX@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158416_k127_526051_2	1380393.JHVP01000020_gene229	5.317e-111	366.0	COG1277@1|root,COG1277@2|Bacteria,2IQBJ@201174|Actinobacteria,4EVZU@85013|Frankiales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_526051_1	1380393.JHVP01000020_gene228	2.553e-173	548.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4EUN8@85013|Frankiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_526051_0	1380393.JHVP01000020_gene227	2.916e-232	724.0	COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria,4EU6P@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158416_k127_526051_5	479435.Kfla_0630	1.73e-77	265.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4DQ84@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_526051_10	1449357.JQLK01000001_gene1348	6.659e-06	57.0	COG4974@1|root,COG4974@2|Bacteria,1WNIT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158416_k127_526051_8	134676.ACPL_6288	3.726e-10	66.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4DFHP@85008|Micromonosporales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_54681_0	1122609.AUGT01000010_gene3797	6.844e-211	678.0	COG0366@1|root,COG0366@2|Bacteria,2GNEC@201174|Actinobacteria,4DUSN@85009|Propionibacteriales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	-	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
SRR25158416_k127_54681_2	211114.JOEF01000001_gene7162	1.632e-86	313.0	COG1082@1|root,COG1082@2|Bacteria,2I2WE@201174|Actinobacteria,4E1N7@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Xylose isomerase-like TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
SRR25158416_k127_54681_1	1289387.AUKW01000018_gene2099	6.214e-101	339.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158416_k127_552907_6	196162.Noca_4855	9.132e-68	233.0	COG1388@1|root,COG1388@2|Bacteria,2IKMC@201174|Actinobacteria	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_552907_5	1120950.KB892742_gene2966	3.164e-75	261.0	COG2141@1|root,COG2141@2|Bacteria,2HVKH@201174|Actinobacteria,4DSDX@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_552907_3	103733.JNYO01000030_gene1459	9.609e-103	341.0	COG3485@1|root,COG3485@2|Bacteria,2GMAP@201174|Actinobacteria,4DXNE@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158416_k127_552907_1	1122182.KB903838_gene4079	3.41e-216	681.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4D931@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_552907_4	1122138.AQUZ01000049_gene2368	3.15e-84	284.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4DPKU@85009|Propionibacteriales	201174|Actinobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158416_k127_552907_2	390989.JOEG01000017_gene6256	9.357e-127	414.0	28MYG@1|root,2ZB5C@2|Bacteria,2H19V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_552907_0	390989.JOEG01000012_gene3459	5e-324	1010.0	COG0451@1|root,COG0560@1|root,COG0451@2|Bacteria,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria	201174|Actinobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4,Sterile
SRR25158416_k127_552907_7	390989.JOEG01000012_gene3460	3.675e-54	202.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,4DJKR@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158416_k127_558442_0	68219.JNXI01000012_gene1312	3.599e-129	421.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria	201174|Actinobacteria	EH	PFAM chorismate	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158416_k127_558442_1	1449346.JQMO01000002_gene1135	2.201e-97	333.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,2M2BV@2063|Kitasatospora	201174|Actinobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158416_k127_558442_2	436229.JOEH01000002_gene3158	1.138e-61	220.0	COG5516@1|root,COG5516@2|Bacteria,2GNZF@201174|Actinobacteria,2NEBZ@228398|Streptacidiphilus	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158416_k127_558442_4	28444.JODQ01000010_gene3189	3.4e-31	128.0	arCOG03175@1|root,32RFA@2|Bacteria,2IFE3@201174|Actinobacteria,4EIQK@85012|Streptosporangiales	201174|Actinobacteria	S	Streptomyces sporulation and cell division protein, SsgA	ssgB	GO:0000003,GO:0000910,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006725,GO:0006732,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009653,GO:0009987,GO:0010564,GO:0010927,GO:0016043,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0018958,GO:0019438,GO:0019748,GO:0019752,GO:0019954,GO:0022402,GO:0022607,GO:0030154,GO:0030312,GO:0030428,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030638,GO:0030639,GO:0031160,GO:0032465,GO:0032467,GO:0032502,GO:0032506,GO:0032989,GO:0032991,GO:0040007,GO:0042180,GO:0042181,GO:0042221,GO:0042244,GO:0042546,GO:0043436,GO:0043648,GO:0043650,GO:0043934,GO:0043936,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044457,GO:0044464,GO:0044550,GO:0045229,GO:0045787,GO:0046189,GO:0046394,GO:0046483,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051301,GO:0051302,GO:0051716,GO:0051726,GO:0051781,GO:0065007,GO:0070590,GO:0070726,GO:0070887,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0090068,GO:0090529,GO:1901110,GO:1901112,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1902074,GO:1902075,GO:1903664,GO:1903666,GO:1990586,GO:2000241,GO:2000243,GO:2000244,GO:2000246	-	-	-	-	-	-	-	-	-	-	SsgA
SRR25158416_k127_558442_3	1123322.KB904647_gene1669	3.097e-32	130.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158416_k127_613977_1	136993.KB900627_gene447	1.072e-83	290.0	COG2706@1|root,COG2706@2|Bacteria,1NG69@1224|Proteobacteria	1224|Proteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158416_k127_613977_2	1177594.MIC448_530062	2.49e-44	164.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4FQJT@85023|Microbacteriaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158416_k127_613977_0	1177594.MIC448_530063	5.169e-140	457.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_613977_3	1120999.JONM01000001_gene1369	0.0005491	44.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158416_k127_619565_0	369723.Strop_2301	4.425e-35	144.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4DENZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_619565_1	1121877.JQKF01000022_gene2296	7.155e-19	90.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria,4CN5U@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158416_k127_625886_1	1454010.JEOE01000042_gene2862	2.508e-128	415.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4F0FM@85016|Cellulomonadaceae	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158416_k127_625886_3	1120950.KB892790_gene2120	5.789e-32	127.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4DS4C@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158416_k127_625886_2	1123321.KB905820_gene5415	4.052e-114	380.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158416_k127_625886_0	479435.Kfla_6670	0.0	1162.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4DN9Q@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158416_k127_636470_15	1123023.JIAI01000001_gene6155	4.127e-38	143.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158416_k127_636470_6	1121272.KB903254_gene6592	7.202e-62	216.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria,4DCTP@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158416_k127_636470_5	710111.FraQA3DRAFT_3503	1.723e-63	219.0	COG0346@1|root,COG0346@2|Bacteria,2IKP7@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_636470_21	1123023.JIAI01000016_gene3357	7.349e-17	86.0	COG1309@1|root,COG1309@2|Bacteria,2GQBQ@201174|Actinobacteria,4DYX0@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158416_k127_636470_10	500153.JOEK01000002_gene199	2.717e-45	183.0	COG1309@1|root,COG1309@2|Bacteria,2GQBQ@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158416_k127_636470_13	710685.MycrhN_4479	1.423e-43	168.0	COG0454@1|root,COG0456@2|Bacteria,2I582@201174|Actinobacteria,23A4U@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_636470_0	1353531.AZNX01000003_gene3044	3.058e-189	602.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,4B92C@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	decarboxylase	rhbB	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158416_k127_636470_7	285535.JOEY01000005_gene7808	7.544e-52	190.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_636470_8	1120950.KB892773_gene1076	2.169e-49	185.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DSC5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_636470_20	66897.DJ64_09320	2.2e-21	104.0	2ED20@1|root,336YY@2|Bacteria,2IAKX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_636470_12	313596.RB2501_12217	5.992e-44	165.0	COG0346@1|root,COG0346@2|Bacteria,4P85Q@976|Bacteroidetes	976|Bacteroidetes	C	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_636470_14	1184607.AUCHE_20_00220	3.655e-43	164.0	COG4115@1|root,COG4115@2|Bacteria,2IQAJ@201174|Actinobacteria	201174|Actinobacteria	S	addiction module toxin, Txe YoeB family	yoeB	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
SRR25158416_k127_636470_16	1210046.B277_10701	3.084e-34	132.0	COG2161@1|root,COG2161@2|Bacteria,2HW6U@201174|Actinobacteria,4FJQ8@85021|Intrasporangiaceae	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158416_k127_636470_2	1121272.KB903249_gene2239	1.757e-127	416.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DB8J@85008|Micromonosporales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158416_k127_636470_17	1223523.H340_02494	2.184e-31	127.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_636470_11	1123251.ATWM01000002_gene43	2.65e-44	168.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4FFNX@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158416_k127_636470_1	1123251.ATWM01000002_gene44	1.492e-135	439.0	COG1171@1|root,COG1171@2|Bacteria,2I8ZW@201174|Actinobacteria,4FIM5@85021|Intrasporangiaceae	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
SRR25158416_k127_636470_3	1449976.KALB_6689	7.03e-126	419.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4E1MS@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158416_k127_636470_9	2340.JV46_06110	2.959e-47	175.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4242,Guanylate_cyc
SRR25158416_k127_636470_18	746697.Aeqsu_2673	2.548e-25	112.0	COG2207@1|root,COG2207@2|Bacteria,4NFVC@976|Bacteroidetes,1HX7J@117743|Flavobacteriia	976|Bacteroidetes	K	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242,HTH_18
SRR25158416_k127_636470_22	1443665.JACA01000024_gene3401	1.043e-13	74.0	2DZVD@1|root,32VJZ@2|Bacteria,4NUB2@976|Bacteroidetes,1I482@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
SRR25158416_k127_636470_19	570268.ANBB01000015_gene3757	2.754e-23	103.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
SRR25158416_k127_636470_4	345341.KUTG_03999	3.056e-98	349.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4E0IZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C
SRR25158416_k127_640229_12	1122939.ATUD01000002_gene1480	1.245e-75	263.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CSXF@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158416_k127_640229_3	1157943.KB892705_gene555	6.514e-143	468.0	COG1070@1|root,COG1070@2|Bacteria,2IE7F@201174|Actinobacteria,238BH@1762|Mycobacteriaceae	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158416_k127_640229_7	1169161.KB897735_gene5159	5.714e-108	361.0	COG0191@1|root,COG0191@2|Bacteria,2H640@201174|Actinobacteria	201174|Actinobacteria	G	Aldolase	-	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158416_k127_640229_5	446466.Cfla_3177	1.076e-129	427.0	COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4F12E@85016|Cellulomonadaceae	201174|Actinobacteria	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
SRR25158416_k127_640229_17	479431.Namu_3966	1.687e-66	240.0	COG0524@1|root,COG1482@1|root,COG0524@2|Bacteria,COG1482@2|Bacteria,2I8X4@201174|Actinobacteria,4EU02@85013|Frankiales	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158416_k127_640229_6	479431.Namu_3967	6.691e-115	383.0	COG1830@1|root,COG1830@2|Bacteria,2IB09@201174|Actinobacteria,4ETKZ@85013|Frankiales	201174|Actinobacteria	G	DeoC/LacD family aldolase	-	-	4.1.2.13,4.1.2.56	ko:K11645,ko:K18287	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158416_k127_640229_4	1081644.IMCC13023_04150	5.445e-140	455.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158416_k127_640229_1	1996.JOFO01000003_gene6145	1.253e-184	582.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4EJUH@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158416_k127_640229_11	591159.ACEZ01000081_gene6559	8.236e-80	271.0	COG1802@1|root,COG1802@2|Bacteria,2I8SM@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158416_k127_640229_10	1380370.JIBA01000015_gene318	6.493e-85	297.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4FFEB@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_640229_20	1283283.ATXA01000001_gene348	2.635e-59	209.0	COG2030@1|root,COG2030@2|Bacteria,2IK2Z@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158416_k127_640229_27	479435.Kfla_0170	6.967e-33	132.0	2E31H@1|root,32Y1W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_640229_9	1286171.EAL2_808p02610	7.661e-88	301.0	COG0663@1|root,COG0663@2|Bacteria,1V72E@1239|Firmicutes,24YU6@186801|Clostridia	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158416_k127_640229_2	234267.Acid_7941	2.442e-155	506.0	COG0076@1|root,COG0076@2|Bacteria,3Y3S7@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158416_k127_640229_30	926566.Terro_3064	1.858e-15	86.0	COG0789@1|root,COG0789@2|Bacteria,3Y5PV@57723|Acidobacteria,2JP31@204432|Acidobacteriia	204432|Acidobacteriia	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
SRR25158416_k127_640229_25	1172179.AUKV01000009_gene4534	6.035e-39	155.0	2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_640229_8	1120949.KB903322_gene2758	1.211e-100	344.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158416_k127_640229_14	1123024.AUII01000012_gene4221	5.95e-70	251.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E188@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158416_k127_640229_13	404589.Anae109_1050	2.508e-72	254.0	COG0604@1|root,COG0604@2|Bacteria,1PFUG@1224|Proteobacteria,43DPN@68525|delta/epsilon subdivisions,2X9UD@28221|Deltaproteobacteria,2Z058@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158416_k127_640229_19	1476876.JOJO01000011_gene3220	1.02e-61	215.0	COG0346@1|root,COG0346@2|Bacteria,2IHU2@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_640229_26	864069.MicloDRAFT_00058040	6.361e-38	145.0	COG0640@1|root,COG0640@2|Bacteria,1N3ZI@1224|Proteobacteria,2UCYW@28211|Alphaproteobacteria,1JYS4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158416_k127_640229_15	1502724.FF80_03852	3.746e-69	237.0	COG3832@1|root,COG3832@2|Bacteria,1RDTP@1224|Proteobacteria,2U795@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158416_k127_640229_16	1089544.KB912942_gene4818	2.079e-67	232.0	COG0748@1|root,COG0748@2|Bacteria,2IP6Y@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158416_k127_640229_0	1120949.KB903294_gene4405	9.683e-229	724.0	COG2866@1|root,COG2866@2|Bacteria,2GJ8D@201174|Actinobacteria,4D9AF@85008|Micromonosporales	201174|Actinobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158416_k127_640229_18	1123319.AUBE01000007_gene3457	7.04e-66	231.0	2AXQV@1|root,31PRS@2|Bacteria,2I93X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_640229_23	1268072.PSAB_07265	1.11e-43	175.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4IPNE@91061|Bacilli,2760S@186822|Paenibacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158416_k127_640229_21	797302.Halru_1825	4.666e-50	195.0	COG0395@1|root,arCOG07556@1|root,arCOG00159@2157|Archaea,arCOG07556@2157|Archaea,2XTU8@28890|Euryarchaeota,23TAS@183963|Halobacteria	183963|Halobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158416_k127_640229_24	1041147.AUFB01000006_gene2273	8.664e-42	167.0	COG1175@1|root,COG1175@2|Bacteria,1NAGS@1224|Proteobacteria,2TUXQ@28211|Alphaproteobacteria,4BMEQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158416_k127_640229_22	1236902.ANAS01000037_gene5390	5.046e-44	176.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria,4EFF8@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10232	ko02010,map02010	M00201,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1,SBP_bac_8
SRR25158416_k127_648035_1	269800.Tfu_2394	5.248e-174	555.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4EFXT@85012|Streptosporangiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158416_k127_648035_3	1120948.KB903243_gene2524	8.264e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria,4E2QJ@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_648035_2	561175.KB894093_gene4312	1.68e-152	494.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4EGFY@85012|Streptosporangiales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158416_k127_648035_0	1380393.JHVP01000001_gene2523	1.137e-199	639.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4ERT2@85013|Frankiales	201174|Actinobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158416_k127_650826_7	1179773.BN6_58240	5.131e-05	46.0	2EBG9@1|root,335GU@2|Bacteria,2IJZI@201174|Actinobacteria,4E4HK@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
SRR25158416_k127_650826_4	1385519.N801_14785	1.43e-23	104.0	COG1917@1|root,COG1917@2|Bacteria,2IQI4@201174|Actinobacteria,4FHHH@85021|Intrasporangiaceae	201174|Actinobacteria	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_650826_6	266117.Rxyl_3191	1.116e-06	53.0	COG1917@1|root,COG1917@2|Bacteria,2I5JH@201174|Actinobacteria,4CTYM@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158416_k127_650826_1	1120950.KB892772_gene1119	1.822e-29	118.0	2BB4Q@1|root,324M3@2|Bacteria,2H9HU@201174|Actinobacteria,4DWEJ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_650826_3	675635.Psed_4405	1.487e-26	119.0	COG1309@1|root,COG1309@2|Bacteria,2GNBS@201174|Actinobacteria,4E4SK@85010|Pseudonocardiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158416_k127_650826_2	765420.OSCT_1705	1.711e-28	121.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,375U7@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158416_k127_650826_0	103733.JNYO01000002_gene678	1.262e-53	190.0	2E6DR@1|root,3311A@2|Bacteria,2IKTW@201174|Actinobacteria,4E80Y@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_651226_14	1120950.KB892759_gene6237	1.389e-70	241.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4DNFX@85009|Propionibacteriales	201174|Actinobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158416_k127_651226_10	1120950.KB892759_gene6236	9.162e-105	349.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4DV9M@85009|Propionibacteriales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	yngF	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158416_k127_651226_19	1122182.KB903813_gene2617	2.458e-37	149.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4DD6M@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158416_k127_651226_15	1120950.KB892759_gene6234	1.381e-65	231.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4DQT5@85009|Propionibacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158416_k127_651226_0	1120950.KB892759_gene6232	0.0	1154.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4DN9B@85009|Propionibacteriales	201174|Actinobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158416_k127_651226_2	436229.JOEH01000034_gene3550	3.017e-283	882.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,2NGRN@228398|Streptacidiphilus	201174|Actinobacteria	I	Carboxyl transferase domain	pccB	GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158416_k127_651226_21	1123024.AUII01000010_gene783	1.063e-06	55.0	2DSSU@1|root,33HAR@2|Bacteria,2GWP2@201174|Actinobacteria,4E7H7@85010|Pseudonocardiales	201174|Actinobacteria	S	Acyl-CoA carboxylase epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_epsilon
SRR25158416_k127_651226_6	1120950.KB892759_gene6228	8.433e-205	651.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DPPG@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158416_k127_651226_16	1386089.N865_18085	1.515e-63	229.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4FFHJ@85021|Intrasporangiaceae	201174|Actinobacteria	D	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
SRR25158416_k127_651226_3	1122138.AQUZ01000060_gene3907	7.212e-275	852.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DTHF@85009|Propionibacteriales	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158416_k127_651226_7	479435.Kfla_1418	2.852e-192	610.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4DNK5@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158416_k127_651226_18	479435.Kfla_1417	1.28e-47	175.0	COG0789@1|root,COG0789@2|Bacteria,2IMV1@201174|Actinobacteria,4DUXA@85009|Propionibacteriales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158416_k127_651226_1	1223523.H340_20981	3.955e-292	908.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158416_k127_651226_13	2074.JNYD01000007_gene1997	1.427e-73	263.0	COG3214@1|root,COG3214@2|Bacteria,2HMGZ@201174|Actinobacteria,4E46J@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158416_k127_651226_12	44060.JODL01000004_gene2450	3.004e-74	265.0	2A4ZY@1|root,30TN1@2|Bacteria,2GMC5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_651226_5	1120950.KB892785_gene237	1.851e-209	659.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4DNPF@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_651226_9	593907.Celgi_2509	2.709e-119	400.0	COG0005@1|root,COG0005@2|Bacteria,2GKEI@201174|Actinobacteria,4F0RK@85016|Cellulomonadaceae	201174|Actinobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158416_k127_651226_11	478801.Ksed_02700	5.099e-76	265.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria	201174|Actinobacteria	M	Epimerase dehydratase	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158416_k127_651226_4	1463856.JOHY01000011_gene6890	5.75e-220	695.0	COG1109@1|root,COG1109@2|Bacteria,2GJ3Q@201174|Actinobacteria	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pmmB	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158416_k127_651226_17	1246448.ANAZ01000015_gene6083	3.722e-55	199.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4EPMU@85012|Streptosporangiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	pmtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158416_k127_651226_8	1120950.KB892785_gene249	2.475e-159	507.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DNUJ@85009|Propionibacteriales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158416_k127_651226_20	1120959.ATXF01000005_gene1445	1.108e-07	54.0	2C562@1|root,347ZN@2|Bacteria,2H8IA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_655895_2	1089545.KB913037_gene8701	9.835e-36	140.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E4JX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_655895_3	926564.KI911697_gene273	1.759e-28	120.0	COG2350@1|root,COG2350@2|Bacteria,2GV9T@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158416_k127_655895_1	1449976.KALB_4780	1.037e-50	187.0	2E4HJ@1|root,32ZCP@2|Bacteria,2IIYC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_655895_0	1123320.KB889748_gene4516	6.418e-291	901.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158416_k127_662614_8	1157708.KB907456_gene2251	9.417e-62	216.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,4AE41@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158416_k127_662614_10	479431.Namu_4112	5.422e-52	188.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4ESRP@85013|Frankiales	201174|Actinobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158416_k127_662614_4	443255.SCLAV_0728	3.992e-82	281.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria	201174|Actinobacteria	E	Shikimate dehydrogenase	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
SRR25158416_k127_662614_5	1449346.JQMO01000003_gene5846	1.117e-71	250.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,2M31S@2063|Kitasatospora	201174|Actinobacteria	S	Uncharacterised protein family (UPF0014)	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158416_k127_662614_15	471852.Tcur_4285	2.213e-37	154.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4EK5Q@85012|Streptosporangiales	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158416_k127_662614_9	1211815.CBYP010000052_gene767	2.988e-55	211.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4ESNJ@85013|Frankiales	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158416_k127_662614_2	1211815.CBYP010000052_gene768	1.408e-110	367.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4ERPZ@85013|Frankiales	201174|Actinobacteria	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	cutM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158416_k127_662614_0	390989.JOEG01000005_gene1867	0.0	1062.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DCJ0@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158416_k127_662614_6	1448389.BAVQ01000025_gene1237	2.207e-68	244.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158416_k127_662614_16	926564.KI911696_gene1082	3.182e-17	89.0	2EJQU@1|root,33DFN@2|Bacteria,2IHQ3@201174|Actinobacteria,4F4JQ@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_662614_7	590998.Celf_1639	4.125e-64	228.0	COG0265@1|root,COG0265@2|Bacteria,2HXVH@201174|Actinobacteria,4F14S@85016|Cellulomonadaceae	201174|Actinobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158416_k127_662614_14	543632.JOJL01000020_gene528	4.981e-48	175.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4DEWK@85008|Micromonosporales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_662614_3	405948.SACE_0696	1.246e-100	340.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4E07V@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158416_k127_662614_12	1713.JOFV01000009_gene282	1.388e-49	184.0	28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4F216@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_662614_13	1463864.JOGO01000057_gene3893	3.448e-48	177.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158416_k127_662614_1	570268.ANBB01000064_gene983	3.602e-134	447.0	COG1409@1|root,COG1409@2|Bacteria,2I59J@201174|Actinobacteria,4EHR8@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158416_k127_662614_11	1122611.KB903985_gene3708	6.189e-50	179.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4EFQV@85012|Streptosporangiales	201174|Actinobacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158416_k127_67492_2	1120949.KB903301_gene6434	5.036e-05	45.0	COG0577@1|root,COG0577@2|Bacteria,2I90E@201174|Actinobacteria,4DBRN@85008|Micromonosporales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158416_k127_67492_1	1121468.AUBR01000007_gene260	3.309e-19	98.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42GQK@68295|Thermoanaerobacterales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_67492_0	1123023.JIAI01000002_gene5243	2.819e-42	159.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4EC0S@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158416_k127_701655_3	446469.Sked_25600	2.853e-35	145.0	COG0515@1|root,COG0515@2|Bacteria,2IMGY@201174|Actinobacteria	201174|Actinobacteria	KLT	Domain of unknown function (DUF4352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
SRR25158416_k127_701655_8	441620.Mpop_5334	3.731e-06	55.0	2CCDG@1|root,32RVE@2|Bacteria,1N8P9@1224|Proteobacteria,2UI79@28211|Alphaproteobacteria,1JVA2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_701655_1	1298863.AUEP01000001_gene814	9.981e-70	251.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria	201174|Actinobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158416_k127_701655_2	1298863.AUEP01000010_gene4478	5.483e-55	203.0	2BVHC@1|root,32QVY@2|Bacteria,2IN31@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_701655_6	153496.JNAB01000013_gene1169	6.812e-11	68.0	2ESJ3@1|root,33K3T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158416_k127_701655_5	471854.Dfer_1108	1.085e-12	82.0	COG0664@1|root,COG3202@1|root,COG0664@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,47JM4@768503|Cytophagia	976|Bacteroidetes	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
SRR25158416_k127_701655_4	765914.ThisiDRAFT_0662	4.807e-19	103.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NB-ARC,TLC,cNMP_binding
SRR25158416_k127_701655_0	1396418.BATQ01000184_gene2632	3.964e-122	421.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158416_k127_71982_15	446471.Xcel_2262	5.043e-21	99.0	COG3360@1|root,COG3360@2|Bacteria,2I0N2@201174|Actinobacteria,4F4X8@85017|Promicromonosporaceae	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158416_k127_71982_7	219305.MCAG_03496	2.041e-100	335.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4DBP6@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158416_k127_71982_5	479432.Sros_6794	9.379e-136	444.0	COG0451@1|root,COG0451@2|Bacteria,2GP01@201174|Actinobacteria,4EI72@85012|Streptosporangiales	201174|Actinobacteria	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158416_k127_71982_2	1068978.AMETH_3839	2.2e-142	462.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,4E2HP@85010|Pseudonocardiales	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158416_k127_71982_9	1068978.AMETH_3838	2.699e-85	288.0	COG1028@1|root,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4E2M4@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158416_k127_71982_1	358823.DF19_21945	1.189e-171	554.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria	201174|Actinobacteria	M	Exporter of polyketide	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158416_k127_71982_4	1206726.BAFV01000039_gene2884	5.236e-141	453.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4FUJH@85025|Nocardiaceae	201174|Actinobacteria	V	ABC transporter ATP-binding	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_71982_11	1242864.D187_006063	1.836e-47	188.0	COG1510@1|root,COG1510@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158416_k127_71982_10	1123320.KB889561_gene4841	3.407e-54	201.0	COG2374@1|root,COG2374@2|Bacteria,2GNED@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158416_k127_71982_3	1380393.JHVP01000005_gene3621	3.554e-142	464.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,4EUTU@85013|Frankiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158416_k127_71982_0	479431.Namu_1838	0.0	1363.0	COG1452@1|root,COG1452@2|Bacteria,2GNM6@201174|Actinobacteria,4ETSY@85013|Frankiales	201174|Actinobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
SRR25158416_k127_71982_13	1120950.KB892754_gene6002	5.13e-45	166.0	COG4430@1|root,COG4430@2|Bacteria,2INBH@201174|Actinobacteria	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158416_k127_71982_12	1380356.JNIK01000018_gene847	5.185e-47	172.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	201174|Actinobacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158416_k127_71982_6	103733.JNYO01000044_gene6636	2.532e-111	371.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DXXN@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_71982_14	1445613.JALM01000016_gene6035	2.302e-25	111.0	COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria,4E3RK@85010|Pseudonocardiales	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_7,Resolvase
SRR25158416_k127_71982_16	35754.JNYJ01000038_gene4925	5.927e-08	61.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	MEDS,STAS,STAS_2
SRR25158416_k127_71982_8	463191.SSEG_09556	3.686e-86	294.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKUC@201174|Actinobacteria	201174|Actinobacteria	KT	protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,SpoIIE
SRR25158416_k127_723394_10	1120950.KB892749_gene3315	2.031e-19	91.0	COG4770@1|root,COG4770@2|Bacteria,2I2DF@201174|Actinobacteria,4DSRA@85009|Propionibacteriales	201174|Actinobacteria	I	Biotin-requiring enzyme	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158416_k127_723394_12	479435.Kfla_5211	5.607e-17	91.0	2DRIE@1|root,33BXS@2|Bacteria,2GYYF@201174|Actinobacteria	201174|Actinobacteria	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158416_k127_723394_9	1120950.KB892749_gene3318	8.837e-30	128.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4DS64@85009|Propionibacteriales	201174|Actinobacteria	K	Putative zinc-finger	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158416_k127_723394_4	1394178.AWOO02000039_gene8676	9.868e-100	329.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4EHPQ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_723394_6	1996.JOFO01000002_gene5729	2.858e-66	232.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4EIJF@85012|Streptosporangiales	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158416_k127_723394_0	68170.KL590487_gene8950	4.102e-170	548.0	COG2170@1|root,COG2170@2|Bacteria,2GKCT@201174|Actinobacteria,4E10A@85010|Pseudonocardiales	201174|Actinobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158416_k127_723394_8	472759.Nhal_2422	1.966e-39	163.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,1WWYR@135613|Chromatiales	135613|Chromatiales	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
SRR25158416_k127_723394_5	1120950.KB892749_gene3321	3.76e-99	332.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4DPFJ@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158416_k127_723394_7	1120950.KB892749_gene3323	9.01e-50	183.0	COG2259@1|root,COG2259@2|Bacteria,2HD6Y@201174|Actinobacteria,4DR14@85009|Propionibacteriales	201174|Actinobacteria	ADL	DoxX	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158416_k127_723394_3	58123.JOFJ01000016_gene4040	5.611e-120	394.0	COG3569@1|root,COG3569@2|Bacteria,2GJTH@201174|Actinobacteria,4EI0T@85012|Streptosporangiales	201174|Actinobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158416_k127_723394_1	110319.CF8_1378	1.275e-166	536.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4DNC2@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158416_k127_723394_2	935866.JAER01000014_gene1773	1.387e-122	399.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,4DNJ3@85009|Propionibacteriales	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158416_k127_725099_1	1033730.CAHG01000013_gene1340	2.497e-151	489.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4DNW9@85009|Propionibacteriales	201174|Actinobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158416_k127_725099_2	67257.JODR01000008_gene3630	4.755e-150	487.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158416_k127_725099_0	269800.Tfu_2768	3.348e-155	502.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria,4EIA4@85012|Streptosporangiales	201174|Actinobacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
SRR25158416_k127_725099_3	269800.Tfu_2767	3.136e-117	390.0	COG0524@1|root,COG0524@2|Bacteria,2GKQP@201174|Actinobacteria,4EFND@85012|Streptosporangiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	scrK	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158416_k127_729186_2	35754.JNYJ01000003_gene6464	4.128e-25	104.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4D9EC@85008|Micromonosporales	201174|Actinobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_729186_1	471852.Tcur_1571	3.79e-51	188.0	COG3296@1|root,COG3296@2|Bacteria,2GT71@201174|Actinobacteria,4EJ6D@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4870
SRR25158416_k127_729186_0	930171.Asphe3_00570	1.682e-177	565.0	2DB9H@1|root,2Z7WW@2|Bacteria,2I2TQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
SRR25158416_k127_73196_0	1121946.AUAX01000034_gene6778	1.933e-21	98.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4DEWK@85008|Micromonosporales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158416_k127_736173_13	1033730.CAHG01000006_gene1189	1.182e-25	110.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4DPII@85009|Propionibacteriales	201174|Actinobacteria	V	FemAB family	femX	-	2.3.2.10	ko:K05363	ko00550,ko01100,map00550,map01100	-	R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
SRR25158416_k127_736173_12	219305.MCAG_02916	7.315e-55	196.0	COG1846@1|root,COG1846@2|Bacteria,2IPBX@201174|Actinobacteria,4DCPX@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158416_k127_736173_4	1032480.MLP_53100	6.791e-111	363.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4DN5G@85009|Propionibacteriales	201174|Actinobacteria	L	Xylose isomerase-like TIM barrel	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158416_k127_736173_14	1385518.N798_03370	3.633e-15	88.0	COG3920@1|root,COG3920@2|Bacteria,2II0F@201174|Actinobacteria,4FH2G@85021|Intrasporangiaceae	201174|Actinobacteria	T	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158416_k127_736173_6	463191.SSEG_03031	1.274e-98	332.0	COG3012@1|root,COG3012@2|Bacteria,2GJ7F@201174|Actinobacteria	201174|Actinobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRR25158416_k127_736173_1	1121946.AUAX01000006_gene3442	1.745e-183	587.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4D8RS@85008|Micromonosporales	201174|Actinobacteria	E	Arginine	arcA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158416_k127_736173_8	1120936.KB907218_gene3381	1.549e-84	286.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,4EHM2@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158416_k127_736173_3	313589.JNB_11904	3.243e-114	397.0	COG3119@1|root,COG3119@2|Bacteria,2H59R@201174|Actinobacteria,4FECJ@85021|Intrasporangiaceae	201174|Actinobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_736173_2	196162.Noca_0168	1.439e-125	420.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria,4DN9M@85009|Propionibacteriales	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158416_k127_736173_7	1120950.KB892773_gene1081	5.569e-85	302.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria,4DNGM@85009|Propionibacteriales	201174|Actinobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158416_k127_736173_5	1120950.KB892812_gene6976	1.097e-107	377.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4DN8Z@85009|Propionibacteriales	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158416_k127_736173_0	926564.KI911649_gene1714	9.845e-194	611.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4F4AK@85017|Promicromonosporaceae	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158416_k127_736173_11	585531.HMPREF0063_10493	1.095e-71	262.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4DQHS@85009|Propionibacteriales	201174|Actinobacteria	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158416_k127_736173_9	1123320.KB889730_gene5953	1.111e-74	260.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria	201174|Actinobacteria	J	hydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158416_k127_736173_10	1463936.JOJI01000068_gene6410	8.152e-73	251.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria	201174|Actinobacteria	S	regulation of cellular protein catabolic process	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR25158416_k127_736173_15	512565.AMIS_74560	1.598e-10	64.0	COG0454@1|root,COG0456@2|Bacteria,2I9GA@201174|Actinobacteria,4DD5V@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158416_k127_738771_2	196367.JNFG01000016_gene4073	4.655e-07	57.0	COG0491@1|root,COG0491@2|Bacteria,1NFZ3@1224|Proteobacteria,2WEMI@28216|Betaproteobacteria,1KHSD@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158416_k127_738771_1	1131553.JIBI01000032_gene2301	9.145e-15	76.0	2BYEJ@1|root,3395P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_738771_0	479431.Namu_2536	2.849e-66	230.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4ERUS@85013|Frankiales	201174|Actinobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR25158416_k127_744807_4	397278.JOJN01000018_gene3520	2.207e-23	99.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4DQAY@85009|Propionibacteriales	201174|Actinobacteria	L	Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_38,rve
SRR25158416_k127_744807_3	383372.Rcas_3189	1.277e-72	257.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158416_k127_744807_1	1429046.RR21198_2053	3.196e-129	420.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4FV76@85025|Nocardiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_744807_2	479432.Sros_8859	8.993e-125	403.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4EGBV@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158416_k127_744807_0	1380370.JIBA01000012_gene3760	1.763e-136	437.0	COG0789@1|root,COG0789@2|Bacteria,2GNID@201174|Actinobacteria,4FGF2@85021|Intrasporangiaceae	201174|Actinobacteria	K	MerR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158416_k127_754307_8	405948.SACE_6986	2.145e-14	76.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria,4E2QX@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YbaK prolyl-tRNA synthetases associated domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158416_k127_754307_3	345341.KUTG_06737	1.038e-71	246.0	COG1881@1|root,COG1881@2|Bacteria,2GMIG@201174|Actinobacteria,4DYXA@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158416_k127_754307_1	397278.JOJN01000008_gene2433	1.402e-186	604.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria,4DPB6@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158416_k127_754307_2	479435.Kfla_2210	6.344e-148	486.0	COG0699@1|root,COG0699@2|Bacteria,2GM68@201174|Actinobacteria,4DPRU@85009|Propionibacteriales	201174|Actinobacteria	S	50S ribosome-binding GTPase	PPA1638	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
SRR25158416_k127_754307_5	1120950.KB892709_gene4158	2.895e-36	151.0	COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4DS96@85009|Propionibacteriales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb2	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158416_k127_754307_0	469371.Tbis_2552	2.181e-309	954.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4DXYM@85010|Pseudonocardiales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158416_k127_754307_4	452652.KSE_54600	5.759e-47	174.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria,2M2ZI@2063|Kitasatospora	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158416_k127_754307_6	1134445.AJJM01000137_gene1182	3.572e-32	130.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158416_k127_754307_7	1123320.KB889629_gene7844	8.163e-28	122.0	2DQ1M@1|root,32UNB@2|Bacteria,2GJD1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_754940_1	675635.Psed_6416	1.097e-153	494.0	COG1294@1|root,COG1294@2|Bacteria,2GN42@201174|Actinobacteria,4E96Z@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158416_k127_754940_0	675635.Psed_6415	3.586e-254	789.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4E9CT@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158416_k127_754940_2	1380347.JNII01000005_gene2988	1.588e-34	142.0	COG2909@1|root,COG2909@2|Bacteria,2I50W@201174|Actinobacteria,4EX4R@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_22,GerE
SRR25158416_k127_770354_10	710696.Intca_0155	9.832e-14	73.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria,4FHJZ@85021|Intrasporangiaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Polysacc_deac_1
SRR25158416_k127_770354_2	298654.FraEuI1c_0845	2.442e-55	200.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
SRR25158416_k127_770354_3	264462.Bd2821	2.917e-51	194.0	COG3591@1|root,COG3591@2|Bacteria,1RBPS@1224|Proteobacteria,42ZKR@68525|delta/epsilon subdivisions,2WUY3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SRR25158416_k127_770354_0	103733.JNYO01000008_gene5417	8.871e-313	996.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2HEQP@201174|Actinobacteria,4DYQU@85010|Pseudonocardiales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158416_k127_770354_9	981383.AEWH01000042_gene1687	4.723e-16	94.0	COG4870@1|root,COG4870@2|Bacteria,1TS2S@1239|Firmicutes,4HAGD@91061|Bacilli	91061|Bacilli	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SRR25158416_k127_770354_6	316274.Haur_1008	2.856e-44	177.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Cornifin,NLPC_P60,SH3_3
SRR25158416_k127_770354_11	446470.Snas_5116	3.094e-08	66.0	2E376@1|root,32Y6Y@2|Bacteria,2H1QX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_770354_12	994479.GL877878_gene241	2.489e-07	60.0	2E376@1|root,32Y6Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_770354_4	218140.BPSY_0147	6.325e-50	198.0	COG3055@1|root,COG5479@1|root,COG3055@2|Bacteria,COG5479@2|Bacteria,2HYIN@201174|Actinobacteria,4CYU1@85004|Bifidobacteriales	201174|Actinobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_770354_1	1380347.JNII01000007_gene391	6.577e-152	513.0	COG0438@1|root,COG2227@1|root,COG0438@2|Bacteria,COG2227@2|Bacteria,2IA6D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR25158416_k127_770354_5	345341.KUTG_02840	1.831e-48	197.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Cons_hypoth95,SAM_MT
SRR25158416_k127_770354_8	883067.HMPREF9237_01546	4.09e-24	119.0	28I6F@1|root,2Z89G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_770354_7	644283.Micau_2846	2.622e-27	121.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158416_k127_778993_0	446468.Ndas_0615	9.978e-128	426.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4EFJQ@85012|Streptosporangiales	201174|Actinobacteria	EK	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158416_k127_778993_3	390989.JOEG01000009_gene1169	5.199e-60	228.0	COG0582@1|root,COG0582@2|Bacteria,2GJ2M@201174|Actinobacteria,4D9U1@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158416_k127_778993_1	644966.Tmar_1325	8.582e-67	233.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,249B1@186801|Clostridia	186801|Clostridia	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
SRR25158416_k127_778993_4	266117.Rxyl_2792	5.324e-57	206.0	COG0819@1|root,COG0819@2|Bacteria,2IGXQ@201174|Actinobacteria	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)	-	-	-	ko:K20896	ko00730,ko01100,map00730,map01100	-	R09993,R11313	RC00197,RC02832	ko00000,ko00001,ko01000	-	-	-	TENA_THI-4
SRR25158416_k127_778993_8	204669.Acid345_2176	1.857e-26	113.0	COG4274@1|root,COG4274@2|Bacteria,3Y8NH@57723|Acidobacteria,2JNFZ@204432|Acidobacteriia	204432|Acidobacteriia	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158416_k127_778993_12	1313172.YM304_29090	4.279e-05	51.0	2BJWW@1|root,32E9A@2|Bacteria,2HGG7@201174|Actinobacteria,4CNDN@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_778993_13	1380394.JADL01000002_gene1597	0.0005555	44.0	COG0053@1|root,COG0053@2|Bacteria,1ND3V@1224|Proteobacteria,2U3WH@28211|Alphaproteobacteria,2JWFJ@204441|Rhodospirillales	204441|Rhodospirillales	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158416_k127_778993_5	1229780.BN381_40003	3.863e-31	124.0	COG0640@1|root,COG0640@2|Bacteria,2IMDE@201174|Actinobacteria,3UWV2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	cmtR	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K21885	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158416_k127_778993_11	1179773.BN6_13730	8.682e-06	53.0	2EQWD@1|root,33IG7@2|Bacteria,2HSG1@201174|Actinobacteria,4EDKP@85010|Pseudonocardiales	201174|Actinobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158416_k127_778993_9	469371.Tbis_0410	1.429e-15	81.0	COG0517@1|root,COG0517@2|Bacteria,2I3TG@201174|Actinobacteria,4EC77@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158416_k127_778993_2	518766.Rmar_0186	1.558e-60	214.0	COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1FJ7D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158416_k127_778993_7	675635.Psed_1332	6.603e-30	132.0	COG0683@1|root,COG0683@2|Bacteria,2H1ZK@201174|Actinobacteria,4EAHR@85010|Pseudonocardiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158416_k127_778993_10	330214.NIDE2258	3.197e-13	72.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158416_k127_778993_6	1485545.JQLW01000007_gene828	6.359e-31	125.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
SRR25158416_k127_782768_8	1123319.AUBE01000002_gene1275	2.482e-07	62.0	2DQB3@1|root,335R8@2|Bacteria,2GMQW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190,DUF4352
SRR25158416_k127_782768_3	525904.Tter_2661	1.955e-75	261.0	COG2365@1|root,COG2365@2|Bacteria,2NRBJ@2323|unclassified Bacteria	2|Bacteria	T	Tyrosine phosphatase family	iphP	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
SRR25158416_k127_782768_2	485913.Krac_2038	2.827e-76	267.0	COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158416_k127_782768_5	1123258.AQXZ01000018_gene340	3.311e-63	227.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4FVZD@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_782768_0	1120949.KB903296_gene9449	1.861e-174	557.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4D9DP@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_782768_6	446470.Snas_3416	2.871e-47	172.0	COG3795@1|root,COG3795@2|Bacteria,2IMHE@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158416_k127_782768_7	1463857.JOFZ01000008_gene495	2.142e-09	59.0	299R2@1|root,2ZWTA@2|Bacteria,2GQXP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_782768_1	1463921.JODF01000001_gene4049	7.271e-148	476.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria	201174|Actinobacteria	E	PHP domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRR25158416_k127_782768_4	1463825.JNXC01000001_gene5988	8.203e-71	250.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,4E0U5@85010|Pseudonocardiales	201174|Actinobacteria	K	TipAS antibiotic-recognition domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
SRR25158416_k127_787422_7	1120950.KB892762_gene5499	1.594e-172	564.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4DPA4@85009|Propionibacteriales	201174|Actinobacteria	M	Transglycosylase	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158416_k127_787422_2	2074.JNYD01000007_gene1958	6.081e-303	940.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DXQ2@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	malL	-	2.4.1.4,3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R01823,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
SRR25158416_k127_787422_21	477641.MODMU_5086	2.142e-54	195.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158416_k127_787422_10	1120950.KB892707_gene4601	8.054e-149	481.0	COG0389@1|root,COG0389@2|Bacteria,2GKHC@201174|Actinobacteria,4DNMF@85009|Propionibacteriales	201174|Actinobacteria	L	impB/mucB/samB family C-terminal domain	dinP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158416_k127_787422_16	1385518.N798_07390	4.283e-84	282.0	COG3467@1|root,COG3467@2|Bacteria,2HGVK@201174|Actinobacteria,4FGIE@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_787422_28	436229.JOEH01000009_gene4564	8.812e-10	59.0	COG1609@1|root,COG1609@2|Bacteria,2GSWK@201174|Actinobacteria,2NJKA@228398|Streptacidiphilus	201174|Actinobacteria	K	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Phage_int_SAM_3,Phage_integrase
SRR25158416_k127_787422_24	66875.JODY01000015_gene718	9.88e-38	150.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158416_k127_787422_11	1048339.KB913029_gene1236	7.931e-122	397.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,4ES1S@85013|Frankiales	201174|Actinobacteria	S	PFAM metallophosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158416_k127_787422_23	500153.JOEK01000001_gene4063	1.224e-43	166.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria	201174|Actinobacteria	S	GatB YqeY	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158416_k127_787422_6	1123322.KB904668_gene3747	2.038e-178	564.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158416_k127_787422_4	469371.Tbis_3528	5.342e-207	654.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4DYQ8@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the aspartokinase family	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158416_k127_787422_13	1123258.AQXZ01000011_gene1621	1.272e-109	364.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria,4G1CT@85025|Nocardiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_787422_15	1123258.AQXZ01000011_gene1614	1.173e-87	302.0	COG1277@1|root,COG1277@2|Bacteria,2IIXQ@201174|Actinobacteria,4G39I@85025|Nocardiaceae	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158416_k127_787422_18	1348663.KCH_36960	3.496e-64	226.0	299JI@1|root,2ZWN1@2|Bacteria,2GMZP@201174|Actinobacteria,2M1D5@2063|Kitasatospora	201174|Actinobacteria	S	Domain of unknown function (DUF5063)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5063
SRR25158416_k127_787422_12	1894.JOER01000011_gene1913	3.281e-114	370.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158416_k127_787422_26	1449976.KALB_238	5.79e-35	137.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4E4G9@85010|Pseudonocardiales	201174|Actinobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158416_k127_787422_5	1298863.AUEP01000015_gene1770	1.106e-186	604.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4DP04@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158416_k127_787422_3	1210046.B277_10069	2.561e-208	662.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,4FERS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158416_k127_787422_22	1380354.JIAN01000005_gene1877	3.816e-46	168.0	COG5450@1|root,32SQA@2|Bacteria,2IKJX@201174|Actinobacteria,4F2HY@85016|Cellulomonadaceae	201174|Actinobacteria	K	Transcription regulator of the Arc MetJ class	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_787422_27	1385518.N798_02095	1.738e-22	104.0	2ED0J@1|root,336XJ@2|Bacteria,2I7ZH@201174|Actinobacteria,4FGMA@85021|Intrasporangiaceae	201174|Actinobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
SRR25158416_k127_787422_8	1120950.KB892742_gene3019	8.466e-171	552.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4DN3N@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-C domain	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
SRR25158416_k127_787422_19	1120950.KB892742_gene2991	3.416e-63	227.0	COG1478@1|root,COG1478@2|Bacteria,2IAKK@201174|Actinobacteria	201174|Actinobacteria	S	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
SRR25158416_k127_787422_9	136273.GY22_09790	2.004e-156	509.0	COG0728@1|root,COG0728@2|Bacteria,2GKBV@201174|Actinobacteria,1WB4S@1268|Micrococcaceae	201174|Actinobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158416_k127_787422_17	1449346.JQMO01000003_gene6716	1.618e-81	280.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,2M1IB@2063|Kitasatospora	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_787422_20	1123320.KB889667_gene2966	8.308e-63	232.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_787422_14	479435.Kfla_3512	8.015e-97	328.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria,4DSSX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_787422_1	1122138.AQUZ01000001_gene1820	0.0	1260.0	COG3696@1|root,COG3696@2|Bacteria,2H303@201174|Actinobacteria,4DWUS@85009|Propionibacteriales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158416_k127_787422_25	479435.Kfla_3516	2.098e-36	161.0	2DS99@1|root,33F32@2|Bacteria,2GXTE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_787422_0	479435.Kfla_3517	0.0	1634.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4DX2V@85009|Propionibacteriales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158416_k127_792322_2	290399.Arth_0399	1.608e-67	238.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158416_k127_792322_0	1463861.JNXE01000001_gene5420	2.261e-84	301.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158416_k127_792322_1	1382306.JNIM01000001_gene1181	5.39e-83	287.0	COG1609@1|root,COG1609@2|Bacteria,2G675@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158416_k127_807047_0	479435.Kfla_3178	0.0	1349.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4DNP8@85009|Propionibacteriales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158416_k127_807047_4	1122611.KB903939_gene401	4.578e-86	289.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4EHKT@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158416_k127_807047_7	1449346.JQMO01000003_gene3002	9.664e-70	239.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,2M26I@2063|Kitasatospora	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158416_k127_807047_6	351607.Acel_1225	5.349e-75	259.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4ESMT@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MerR	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158416_k127_807047_8	1123322.KB904735_gene1415	1.835e-63	224.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158416_k127_807047_9	1120950.KB892707_gene5032	5.579e-56	198.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4DR4B@85009|Propionibacteriales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158416_k127_807047_10	67315.JOBD01000001_gene895	3.213e-48	185.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158416_k127_807047_12	1386089.N865_18235	4.271e-41	165.0	COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4FGYG@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
SRR25158416_k127_807047_11	1120950.KB892707_gene5029	3.717e-48	188.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4DR0G@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158416_k127_807047_5	196162.Noca_2718	9.27e-76	258.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4DQ8M@85009|Propionibacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158416_k127_807047_13	1120950.KB892747_gene3706	8.255e-30	130.0	2DBAY@1|root,2Z84S@2|Bacteria,2IAPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_807047_2	1463861.JNXE01000061_gene1505	1.53e-212	664.0	COG1052@1|root,COG1052@2|Bacteria,2GN2C@201174|Actinobacteria	201174|Actinobacteria	CH	Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158416_k127_807047_1	1283283.ATXA01000023_gene233	4.639e-254	801.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	201174|Actinobacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
SRR25158416_k127_807047_3	234621.RER_40240	4.801e-187	596.0	COG4191@1|root,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria,4FWIC@85025|Nocardiaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
SRR25158416_k127_807047_14	285535.JOEY01000035_gene3715	2.178e-06	49.0	COG0477@1|root,COG0477@2|Bacteria,2H6BY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158416_k127_814188_25	468556.AQYG01000041_gene3588	1.356e-07	58.0	COG1733@1|root,COG1733@2|Bacteria,2IJCU@201174|Actinobacteria,4GGU0@85026|Gordoniaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158416_k127_814188_9	1172188.KB911820_gene2380	4.89e-115	375.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,4FGJN@85021|Intrasporangiaceae	201174|Actinobacteria	H	Deaminase reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158416_k127_814188_17	1123024.AUII01000028_gene2486	2.58e-49	183.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GN0H@201174|Actinobacteria,4E3TF@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158416_k127_814188_8	1123024.AUII01000034_gene2674	3.91e-135	441.0	COG0438@1|root,COG0438@2|Bacteria,2GKX4@201174|Actinobacteria,4E2H9@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158416_k127_814188_4	1123024.AUII01000034_gene2675	1.186e-170	563.0	COG0074@1|root,COG0074@2|Bacteria,2GN20@201174|Actinobacteria,4E87Z@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
SRR25158416_k127_814188_11	756499.Desde_0779	3.86e-81	281.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,264F3@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158416_k127_814188_6	2074.JNYD01000040_gene2969	7.454e-152	488.0	COG2516@1|root,COG2516@2|Bacteria,2GN07@201174|Actinobacteria,4E1DF@85010|Pseudonocardiales	201174|Actinobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158416_k127_814188_18	1123024.AUII01000053_gene175	4.725e-42	166.0	COG2153@1|root,COG2153@2|Bacteria	2|Bacteria	K	protein acetylation	yyaT	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
SRR25158416_k127_814188_10	1123024.AUII01000028_gene2487	2.892e-106	354.0	COG2144@1|root,COG2144@2|Bacteria,2GM78@201174|Actinobacteria,4E1YB@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR synthase related protein, C-terminal domain	thiL_1	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C,Acetyltransf_1,Acetyltransf_10
SRR25158416_k127_814188_12	675635.Psed_6288	2.431e-80	278.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4E51E@85010|Pseudonocardiales	201174|Actinobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158416_k127_814188_15	710687.KI912270_gene4823	1.067e-66	252.0	2DBFP@1|root,2Z8ZG@2|Bacteria,2IAVA@201174|Actinobacteria,23DCC@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_814188_2	675635.Psed_1621	5.819e-194	622.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4E8M1@85010|Pseudonocardiales	201174|Actinobacteria	F	Lyase	-	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158416_k127_814188_14	675635.Psed_1622	2.891e-75	271.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4EBSU@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158416_k127_814188_0	675635.Psed_1623	5.497e-219	691.0	COG0165@1|root,COG0165@2|Bacteria,2I9W9@201174|Actinobacteria,4EA9J@85010|Pseudonocardiales	201174|Actinobacteria	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158416_k127_814188_3	1123024.AUII01000053_gene171	1.963e-176	569.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria,4E8S3@85010|Pseudonocardiales	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
SRR25158416_k127_814188_20	675635.Psed_1617	4.533e-30	136.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158416_k127_814188_22	68170.KL590493_gene6389	2.274e-22	103.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E3IX@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_814188_23	1123023.JIAI01000007_gene1826	1.042e-18	98.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4E3IX@85010|Pseudonocardiales	201174|Actinobacteria	V	Domain of unknown function (DUF222)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_814188_24	494419.ALPM01000063_gene2195	1.701e-09	69.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,1WCC1@1268|Micrococcaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_814188_27	1304865.JAGF01000001_gene739	9.621e-05	51.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158416_k127_814188_5	994479.GL877878_gene1024	3.45e-152	490.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
SRR25158416_k127_814188_26	591158.SSMG_07543	8.227e-07	55.0	COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives IS30 family	-	-	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_38,rve
SRR25158416_k127_814188_1	1123024.AUII01000053_gene167	2.894e-204	644.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EBET@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158416_k127_814188_13	675635.Psed_1625	7.21e-76	268.0	COG2044@1|root,COG2044@2|Bacteria,2GJQS@201174|Actinobacteria,4DYQM@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158416_k127_814188_7	1123024.AUII01000005_gene2477	1.652e-149	477.0	COG2159@1|root,COG2159@2|Bacteria,2I9E4@201174|Actinobacteria,4E0Z3@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158416_k127_814188_16	477641.MODMU_3091	3.102e-57	214.0	COG2273@1|root,COG3306@1|root,COG2273@2|Bacteria,COG3306@2|Bacteria,2IDV0@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SRR25158416_k127_814188_19	477641.MODMU_3090	8.243e-35	139.0	COG3774@1|root,COG3774@2|Bacteria	2|Bacteria	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Gly_transf_sug
SRR25158416_k127_815703_3	1120949.KB903319_gene9854	7.387e-21	94.0	COG0277@1|root,COG2141@1|root,COG0277@2|Bacteria,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria,4DBS5@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,Bac_luciferase,FAD_binding_4,Hemerythrin
SRR25158416_k127_815703_4	546262.NEICINOT_03891	0.0004335	46.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,2KQ07@206351|Neisseriales	206351|Neisseriales	IQ	Psort location Cytoplasmic, score 9.26	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158416_k127_815703_2	350058.Mvan_5965	1.089e-28	125.0	COG2801@1|root,COG2801@2|Bacteria,2I3ET@201174|Actinobacteria	201174|Actinobacteria	L	Pfam Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
SRR25158416_k127_815703_1	1238186.AOCN01000012_gene1262	1.82e-32	142.0	COG0446@1|root,COG0580@1|root,COG0446@2|Bacteria,COG0580@2|Bacteria,2H7WY@201174|Actinobacteria,4FKDZ@85023|Microbacteriaceae	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158416_k127_815703_0	35754.JNYJ01000006_gene5303	5.827e-154	490.0	COG3408@1|root,COG3408@2|Bacteria,2IB24@201174|Actinobacteria,4D8TX@85008|Micromonosporales	201174|Actinobacteria	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158416_k127_817569_1	298655.KI912266_gene989	3.025e-18	93.0	2EFF7@1|root,33981@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_817569_0	1205910.B005_0669	1.347e-36	143.0	COG2267@1|root,COG2267@2|Bacteria,2IITW@201174|Actinobacteria	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158416_k127_817569_3	1380390.JIAT01000010_gene4683	5.622e-11	67.0	COG3576@1|root,COG3576@2|Bacteria,2I46F@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_817569_2	479435.Kfla_4191	1.134e-16	80.0	COG1522@1|root,COG1522@2|Bacteria,2IG2K@201174|Actinobacteria,4DS0H@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix ASNC type	lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158416_k127_817569_4	1075090.GOAMR_66_00010	1.334e-09	58.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4GBUX@85026|Gordoniaceae	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_825247_5	500153.JOEK01000001_gene3538	7.46e-103	345.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria	201174|Actinobacteria	M	Glycine betaine	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158416_k127_825247_12	1289387.AUKW01000020_gene2772	1.895e-81	277.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158416_k127_825247_14	1137269.AZWL01000011_gene3275	8.636e-74	259.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria	201174|Actinobacteria	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158416_k127_825247_1	443255.SCLAV_2406	2.636e-167	535.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	opuCA	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158416_k127_825247_28	1123322.KB904702_gene165	1.216e-12	74.0	2DRQG@1|root,33CMQ@2|Bacteria,2IFEG@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3180
SRR25158416_k127_825247_18	1120950.KB892801_gene1722	1.967e-56	205.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4DQ88@85009|Propionibacteriales	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158416_k127_825247_22	996637.SGM_4283	2.265e-45	166.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158416_k127_825247_24	1122138.AQUZ01000014_gene7011	3.916e-35	140.0	COG4319@1|root,COG4319@2|Bacteria,2GNV0@201174|Actinobacteria,4DVQ0@85009|Propionibacteriales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158416_k127_825247_4	33898.JRHJ01000055_gene5895	4.101e-108	364.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158416_k127_825247_8	749414.SBI_05922	4.727e-88	298.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158416_k127_825247_0	1120950.KB892801_gene1716	1.814e-298	940.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4DP9B@85009|Propionibacteriales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158416_k127_825247_9	935839.JAGJ01000020_gene117	5.115e-85	287.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4F38R@85017|Promicromonosporaceae	201174|Actinobacteria	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158416_k127_825247_7	1048339.KB913029_gene2248	8.385e-91	311.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4ERWN@85013|Frankiales	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR25158416_k127_825247_2	1449353.JQMQ01000005_gene3305	1.539e-133	434.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,2NGVY@228398|Streptacidiphilus	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158416_k127_825247_6	1120950.KB892801_gene1711	6.314e-92	321.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4DN2Y@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158416_k127_825247_10	926564.KI911634_gene3089	6.707e-83	280.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4F3X9@85017|Promicromonosporaceae	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR25158416_k127_825247_17	928724.SacglDRAFT_03695	4.57e-65	228.0	297W1@1|root,2ZV2M@2|Bacteria,2II0V@201174|Actinobacteria,4E3WZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158416_k127_825247_21	1463900.JOIX01000092_gene1710	1.512e-45	175.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158416_k127_825247_16	1303692.SFUL_5319	1.21e-66	239.0	COG3210@1|root,COG3210@2|Bacteria,2I2VF@201174|Actinobacteria	201174|Actinobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_825247_11	1120950.KB892707_gene4821	8.339e-82	277.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4DQUR@85009|Propionibacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158416_k127_825247_13	749927.AMED_6486	5.005e-78	271.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4E0A3@85010|Pseudonocardiales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	prsR	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR25158416_k127_825247_20	1122138.AQUZ01000014_gene7028	4.962e-47	173.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4DRYK@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_825247_15	1033730.CAHG01000016_gene541	1.166e-69	247.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Glyco_hydro_2,Virul_fac_BrkB
SRR25158416_k127_825247_23	1283283.ATXA01000001_gene544	3.095e-40	154.0	COG1714@1|root,COG1714@2|Bacteria,2IN6K@201174|Actinobacteria,4ETDQ@85013|Frankiales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158416_k127_825247_26	1283283.ATXA01000001_gene545	4.301e-19	98.0	2EEE7@1|root,33888@2|Bacteria,2IMP5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_825247_3	1120949.KB903294_gene4404	4.945e-122	412.0	COG2304@1|root,COG2304@2|Bacteria,2H3JW@201174|Actinobacteria,4DHZC@85008|Micromonosporales	201174|Actinobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_825247_19	1137271.AZUM01000002_gene2407	9.928e-53	202.0	COG3568@1|root,COG3568@2|Bacteria,2I4CT@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158416_k127_825247_25	1278073.MYSTI_04769	9.202e-30	124.0	COG3157@1|root,COG3157@2|Bacteria,1MXFB@1224|Proteobacteria,42UFI@68525|delta/epsilon subdivisions,2WQZ4@28221|Deltaproteobacteria,2YW32@29|Myxococcales	28221|Deltaproteobacteria	S	Type VI secretion system effector, Hcp	tssD	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SRR25158416_k127_825247_27	1146883.BLASA_0586	4.291e-15	76.0	COG3358@1|root,COG3358@2|Bacteria,2GP66@201174|Actinobacteria,4EVG7@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158416_k127_848575_4	471853.Bcav_0588	1.167e-06	61.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158416_k127_848575_1	471853.Bcav_0589	3.697e-124	410.0	COG4585@1|root,COG4585@2|Bacteria,2GSZK@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158416_k127_848575_2	526225.Gobs_2856	5.946e-111	363.0	COG0586@1|root,COG0586@2|Bacteria,2I03Q@201174|Actinobacteria,4EW6F@85013|Frankiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158416_k127_848575_3	196162.Noca_4911	1.228e-99	330.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DPV2@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_848575_0	196162.Noca_4911	5.048e-154	490.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DPV2@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158416_k127_86987_4	313589.JNB_01200	4.399e-33	130.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4FF88@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_86987_2	1120934.KB894408_gene4666	1.135e-87	299.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4E1BJ@85010|Pseudonocardiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158416_k127_86987_7	263358.VAB18032_16910	0.0006339	46.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4DB2V@85008|Micromonosporales	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_86987_3	1150864.MILUP08_42675	3.795e-85	286.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4DB2V@85008|Micromonosporales	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_86987_1	882083.SacmaDRAFT_4640	3.328e-187	587.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4E1PX@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158416_k127_86987_0	1120949.KB903307_gene1400	5.346e-192	600.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4D8PE@85008|Micromonosporales	201174|Actinobacteria	S	epoxide hydrolase	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
SRR25158416_k127_875922_2	1209984.BN978_05218	5.411e-113	371.0	COG0524@1|root,COG0524@2|Bacteria,2I9EV@201174|Actinobacteria,23D2E@1762|Mycobacteriaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158416_k127_875922_0	1209984.BN978_05217	4.269e-281	884.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,234CK@1762|Mycobacteriaceae	201174|Actinobacteria	G	hydrolase family 65, central catalytic	kojP	-	2.4.1.230	ko:K10231	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158416_k127_875922_4	1158050.KB895452_gene675	3.687e-36	144.0	2BAAG@1|root,323QP@2|Bacteria,2H8F7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_875922_7	2002.JOEQ01000061_gene7184	4.207e-12	72.0	2ER8X@1|root,33IUI@2|Bacteria,2IRAS@201174|Actinobacteria,4EQ4C@85012|Streptosporangiales	201174|Actinobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
SRR25158416_k127_875922_1	479434.Sthe_1357	1.499e-195	630.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,27YSI@189775|Thermomicrobia	189775|Thermomicrobia	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158416_k127_875922_5	1267533.KB906734_gene3937	7.989e-34	133.0	COG1504@1|root,COG1504@2|Bacteria	2|Bacteria	L	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
SRR25158416_k127_875922_6	1082933.MEA186_23816	2.641e-27	116.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.1.1.137,2.3.1.1	ko:K00537,ko:K00619,ko:K07755	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
SRR25158416_k127_875922_3	1386089.N865_00320	3.651e-62	218.0	2DDHE@1|root,2ZI3V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_875922_8	1194165.CAJF01000039_gene1713	2.923e-07	62.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FNJ1@85023|Microbacteriaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158416_k127_929393_6	67267.JNXT01000040_gene4650	8.414e-99	338.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_929393_11	1120960.ATXG01000017_gene1397	1.076e-38	156.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria,4FRYG@85023|Microbacteriaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_929393_9	1120960.ATXG01000017_gene1397	2.629e-42	160.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria,4FRYG@85023|Microbacteriaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_929393_8	543632.JOJL01000004_gene4133	1.438e-58	215.0	COG2197@1|root,COG2197@2|Bacteria,2ICWH@201174|Actinobacteria,4DHB5@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158416_k127_929393_3	543632.JOJL01000004_gene4132	2.062e-114	396.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DB80@85008|Micromonosporales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	degS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158416_k127_929393_5	1048339.KB913029_gene27	7.125e-106	355.0	COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,2GKXN@201174|Actinobacteria,4EXF5@85013|Frankiales	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_929393_1	469371.Tbis_2652	9.094e-129	422.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4DYHD@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
SRR25158416_k127_929393_7	1283287.KB822575_gene590	9.576e-63	225.0	COG0346@1|root,COG0346@2|Bacteria,2HEJY@201174|Actinobacteria,4DQXB@85009|Propionibacteriales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_929393_0	436229.JOEH01000016_gene7262	2.41e-149	480.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,2NEAY@228398|Streptacidiphilus	201174|Actinobacteria	E	Peptidase family M28	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158416_k127_929393_4	1120950.KB892823_gene507	9.314e-108	358.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4DPM7@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158416_k127_929393_2	1120950.KB892823_gene505	9.232e-129	421.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4DNDN@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP2	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158416_k127_929393_10	479432.Sros_5814	4.732e-42	159.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4EJXN@85012|Streptosporangiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158416_k127_930040_3	1122182.KB903818_gene1972	2.111e-172	547.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4D9MX@85008|Micromonosporales	201174|Actinobacteria	G	Fructose-bisphosphate aldolase	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158416_k127_930040_9	1283287.KB822577_gene3207	4.963e-44	173.0	COG2197@1|root,COG2197@2|Bacteria,2GSEU@201174|Actinobacteria,4DTUU@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158416_k127_930040_1	1122138.AQUZ01000031_gene4160	6.533e-218	683.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4DNMU@85009|Propionibacteriales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158416_k127_930040_11	1122611.KB903962_gene4482	6.976e-05	50.0	2BUKG@1|root,32PX0@2|Bacteria,2HB2I@201174|Actinobacteria,4EQ95@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_930040_7	1056816.JAFQ01000004_gene2532	9.313e-60	217.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4G0KU@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158416_k127_930040_6	1429046.RR21198_4242	1.285e-65	226.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,4G0ZN@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158416_k127_930040_8	1068978.AMETH_3532	3.514e-52	191.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria	201174|Actinobacteria	K	TetR Family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158416_k127_930040_0	1123322.KB904708_gene123	8.381e-231	735.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158416_k127_930040_4	1449346.JQMO01000003_gene4446	2.939e-172	552.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,2M0YD@2063|Kitasatospora	201174|Actinobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158416_k127_930040_5	1120950.KB892790_gene2130	6.896e-131	423.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4DNM5@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158416_k127_930040_2	405948.SACE_7153	9.158e-217	681.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4E0FG@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158416_k127_930040_10	313589.JNB_15743	1.185e-06	54.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4FG0Z@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158416_k127_930518_2	28042.GU90_17205	4.18e-67	229.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4E07K@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158416_k127_930518_3	196162.Noca_3517	6.132e-55	198.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4DNPF@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_930518_1	397278.JOJN01000001_gene2858	3.218e-80	271.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4DNPF@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158416_k127_930518_0	1089545.KB913037_gene3915	1.302e-185	593.0	COG5421@1|root,COG5421@2|Bacteria,2GK2A@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158416_k127_930590_6	1043205.AFYF01000072_gene2217	8.226e-05	45.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4FF88@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_930590_5	1160718.SU9_11413	5.384e-05	48.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158416_k127_930590_0	408672.NBCG_04626	6.148e-239	772.0	COG2357@1|root,COG4328@1|root,COG2357@2|Bacteria,COG4328@2|Bacteria,2GKF8@201174|Actinobacteria,4DPS6@85009|Propionibacteriales	201174|Actinobacteria	Q	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,RelA_SpoT
SRR25158416_k127_930590_1	479431.Namu_4331	5.316e-105	349.0	COG0604@1|root,COG0604@2|Bacteria,2GIWC@201174|Actinobacteria,4EUY3@85013|Frankiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158416_k127_930590_3	1157637.KB892092_gene6902	1.321e-26	121.0	COG0412@1|root,COG0412@2|Bacteria,2H3SA@201174|Actinobacteria	201174|Actinobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158416_k127_930590_2	479435.Kfla_1243	1.997e-62	228.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158416_k127_930590_4	1120949.KB903312_gene594	2.104e-21	96.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158416_k127_959834_3	405948.SACE_5343	7.474e-167	543.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DY4J@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158416_k127_959834_0	1122138.AQUZ01000017_gene6662	6.137e-182	576.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4DN32@85009|Propionibacteriales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158416_k127_959834_11	1123023.JIAI01000006_gene369	1.883e-34	135.0	COG3296@1|root,COG3296@2|Bacteria,2HZEM@201174|Actinobacteria,4ECWY@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158416_k127_959834_6	1120950.KB892739_gene3996	1.176e-145	469.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4DP2Y@85009|Propionibacteriales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
SRR25158416_k127_959834_2	1123320.KB889675_gene4102	1.832e-167	533.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158416_k127_959834_9	1304865.JAGF01000001_gene3299	1.238e-44	177.0	COG5401@1|root,COG5401@2|Bacteria,2IQ3Y@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158416_k127_959834_8	1236902.ANAS01000009_gene2620	1.148e-50	186.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4EGWT@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158416_k127_959834_10	68219.JNXI01000001_gene6256	6.265e-43	163.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158416_k127_959834_4	479435.Kfla_2421	8.485e-155	497.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4DPI2@85009|Propionibacteriales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158416_k127_959834_7	105420.BBPO01000023_gene6449	7.358e-62	219.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,2NHIA@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterized protein family UPF0054	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158416_k127_959834_1	1120950.KB892739_gene3991	3.786e-176	565.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4DNND@85009|Propionibacteriales	201174|Actinobacteria	S	Transporter associated domain	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158416_k127_959834_12	526225.Gobs_1661	2.568e-27	118.0	COG0295@1|root,COG0295@2|Bacteria,2IM42@201174|Actinobacteria,4ETET@85013|Frankiales	201174|Actinobacteria	F	cytidine deaminase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_959834_5	1210045.ALNP01000005_gene3807	4.99e-148	475.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria	201174|Actinobacteria	M	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158416_k127_960304_0	994479.GL877878_gene2948	6.104e-230	724.0	COG5421@1|root,COG5421@2|Bacteria,2GKNQ@201174|Actinobacteria,4E23E@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158416_k127_966614_3	67281.JNZZ01000025_gene4870	2.975e-35	135.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,418Z8@629295|Streptomyces griseus group	201174|Actinobacteria	I	Thiolase, N-terminal domain	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158416_k127_966614_0	196162.Noca_1986	2.6e-240	753.0	COG4799@1|root,COG4799@2|Bacteria,2I16G@201174|Actinobacteria,4DNAY@85009|Propionibacteriales	201174|Actinobacteria	I	Malonate decarboxylase gamma subunit (MdcE)	accD6	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009317,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019367,GO:0019752,GO:0030312,GO:0030497,GO:0032787,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:0072330,GO:1901575,GO:1901576,GO:1902494	2.1.3.15,6.4.1.2,6.4.1.3	ko:K18472	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04386	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158416_k127_966614_2	1122138.AQUZ01000004_gene935	5.872e-84	281.0	299E4@1|root,2ZWGX@2|Bacteria,2GM90@201174|Actinobacteria,4DQ7U@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3145
SRR25158416_k127_966614_1	446469.Sked_21250	8.951e-102	341.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158416_k127_968947_9	1150864.MILUP08_42435	9.573e-145	470.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria,4DC2F@85008|Micromonosporales	201174|Actinobacteria	E	aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158416_k127_968947_8	1157637.KB892156_gene3936	2.292e-147	479.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158416_k127_968947_13	1048339.KB913029_gene4175	2.35e-121	399.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4ERMG@85013|Frankiales	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158416_k127_968947_5	1123322.KB904724_gene2045	3.54e-187	587.0	COG0665@1|root,COG0665@2|Bacteria,2I9UF@201174|Actinobacteria	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158416_k127_968947_6	1440774.Y900_009795	8.308e-181	573.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,234RT@1762|Mycobacteriaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_29,HTH_32
SRR25158416_k127_968947_22	526225.Gobs_2142	1.987e-89	318.0	COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158416_k127_968947_0	1123322.KB904647_gene1742	0.0	1230.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria	201174|Actinobacteria	L	DEAD DEAH box helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158416_k127_968947_19	196162.Noca_2655	2.68e-99	332.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4DPPK@85009|Propionibacteriales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
SRR25158416_k127_968947_24	471852.Tcur_2320	1.78e-71	252.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4EH0R@85012|Streptosporangiales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158416_k127_968947_28	1463926.JOCA01000021_gene6546	2.598e-14	78.0	COG1826@1|root,COG1826@2|Bacteria,2GQQX@201174|Actinobacteria	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158416_k127_968947_12	1120950.KB892708_gene4435	7.375e-122	400.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4DP7N@85009|Propionibacteriales	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158416_k127_968947_17	1120950.KB892708_gene4434	9.094e-108	357.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4DNBD@85009|Propionibacteriales	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158416_k127_968947_7	479432.Sros_5863	3.692e-155	497.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria,4EFJW@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158416_k127_968947_26	1283283.ATXA01000001_gene562	2.848e-51	196.0	COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4ET6I@85013|Frankiales	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbB	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158416_k127_968947_2	1120950.KB892708_gene4431	9.086e-270	833.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4DPF1@85009|Propionibacteriales	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158416_k127_968947_20	1184609.KILIM_006_00080	4.847e-95	321.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4F6S2@85018|Dermatophilaceae	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158416_k127_968947_14	479435.Kfla_3226	1.235e-118	387.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4DPD6@85009|Propionibacteriales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158416_k127_968947_27	1348663.KCH_67710	1.143e-17	85.0	2E9C2@1|root,333JS@2|Bacteria,2IQ5V@201174|Actinobacteria,2M3IB@2063|Kitasatospora	201174|Actinobacteria	O	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR25158416_k127_968947_3	1120950.KB892708_gene4427	2.106e-264	820.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4DMZX@85009|Propionibacteriales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158416_k127_968947_21	1032480.MLP_50370	1.045e-92	316.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4DPXP@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158416_k127_968947_1	1003195.SCAT_5170	4.825e-303	937.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria	201174|Actinobacteria	O	AAA ATPase forming ring-shaped complexes	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158416_k127_968947_11	1463845.JOIG01000002_gene2523	3.108e-132	426.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158416_k127_968947_18	1120950.KB892708_gene4422	8.723e-106	369.0	COG1994@1|root,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DNGY@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SRR25158416_k127_968947_16	471852.Tcur_2304	2.293e-113	374.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,4EH9Q@85012|Streptosporangiales	201174|Actinobacteria	L	Protein of unknown function (DUF2800)	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158416_k127_968947_23	266117.Rxyl_0283	4.76e-81	279.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158416_k127_968947_15	479431.Namu_0799	5.431e-117	381.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4ES91@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158416_k127_968947_4	479431.Namu_0800	8.867e-260	827.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158416_k127_968947_10	479431.Namu_0662	1.33e-142	466.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EUQ8@85013|Frankiales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158416_k127_968947_25	103733.JNYO01000035_gene3004	2.244e-65	226.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4DYK6@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	appD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158416_k127_971977_1	1122138.AQUZ01000049_gene2367	1.145e-243	765.0	COG0520@1|root,COG0520@2|Bacteria,2GP7W@201174|Actinobacteria,4DNX7@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158416_k127_971977_0	1713.JOFV01000006_gene2802	1.492e-255	807.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4F289@85016|Cellulomonadaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158416_k127_971977_2	1245475.ANAE01000094_gene4372	5.22e-52	191.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4EJZ6@85012|Streptosporangiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158416_k127_971977_3	471852.Tcur_2459	1.066e-09	67.0	COG1366@1|root,COG1366@2|Bacteria,2I1VE@201174|Actinobacteria,4EPVZ@85012|Streptosporangiales	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
## 4064 queries scanned
## Total time (seconds): 98.32455158233643
## Rate: 41.33 q/s