## Mon Dec 15 13:10:07 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158433_bin.5.fa -m mmseqs --itype genome -o SRR25158433_bin.5 --output_dir /data/result/bins/wyx/egg/SRR25158433_bin.5 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158433_k127_1004984_6	469383.Cwoe_1712	1.101e-28	124.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158433_k127_1004984_1	263358.VAB18032_03915	1.397e-113	377.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4DAUR@85008|Micromonosporales	201174|Actinobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158433_k127_1004984_2	1283299.AUKG01000001_gene2180	3.916e-103	340.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4CRF2@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158433_k127_1004984_3	469383.Cwoe_5567	1.297e-82	287.0	COG0561@1|root,COG0561@2|Bacteria,2HU8Y@201174|Actinobacteria,4CTUW@84995|Rubrobacteria	84995|Rubrobacteria	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1004984_4	42256.RradSPS_0278	3.078e-56	208.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CT4V@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158433_k127_1004984_0	469383.Cwoe_5571	5.412e-307	957.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4CPIU@84995|Rubrobacteria	84995|Rubrobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158433_k127_1004984_5	266117.Rxyl_0512	1.435e-29	138.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158433_k127_101762_2	1380390.JIAT01000003_gene5432	2.4e-76	259.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CPH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158433_k127_101762_3	1283299.AUKG01000002_gene5327	2.465e-33	132.0	COG0781@1|root,COG0781@2|Bacteria,2HP01@201174|Actinobacteria,4CQ9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158433_k127_101762_1	1380390.JIAT01000003_gene5435	1.326e-105	353.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4CP7H@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158433_k127_101762_0	469383.Cwoe_3076	5.847e-165	530.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CPJ0@84995|Rubrobacteria	84995|Rubrobacteria	HI	1-deoxy-D-xylulose-5-phosphate synthase	-	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158433_k127_1024708_0	1303518.CCALI_00290	3.879e-249	781.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158433_k127_1024708_2	1380390.JIAT01000012_gene3184	2.998e-46	186.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
SRR25158433_k127_1024708_3	469383.Cwoe_0806	4.402e-31	124.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158433_k127_1024708_1	469383.Cwoe_0807	1.175e-154	499.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CP95@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158433_k127_1024708_4	1380390.JIAT01000009_gene1491	1.098e-23	105.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CQ7C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158433_k127_103755_10	1463854.JOHT01000009_gene1787	4.744e-51	188.0	COG1309@1|root,COG1309@2|Bacteria,2ICNH@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_103755_7	47763.JNZA01000020_gene2201	7.119e-65	228.0	2C3AX@1|root,2Z859@2|Bacteria,2IC6Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_103755_18	1283299.AUKG01000001_gene1580	7.159e-14	74.0	2BCFA@1|root,3260X@2|Bacteria,2HBC1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_103755_14	469383.Cwoe_1850	3.053e-39	151.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4CQGR@84995|Rubrobacteria	84995|Rubrobacteria	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158433_k127_103755_1	469383.Cwoe_1846	3.531e-170	538.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPXX@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158433_k127_103755_16	469383.Cwoe_1845	6.72e-36	138.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CTFG@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158433_k127_103755_2	1380390.JIAT01000014_gene6127	1.667e-152	491.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158433_k127_103755_17	1283299.AUKG01000002_gene4564	2.809e-30	128.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158433_k127_103755_6	706587.Desti_4145	2.306e-90	306.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MQ6Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158433_k127_103755_8	1380390.JIAT01000014_gene6128	2.894e-60	219.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4CSHA@84995|Rubrobacteria	84995|Rubrobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158433_k127_103755_13	469383.Cwoe_1560	2.176e-40	161.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158433_k127_103755_5	1283299.AUKG01000001_gene3145	2.175e-90	305.0	COG2197@1|root,COG2197@2|Bacteria,2HFRK@201174|Actinobacteria,4CS96@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158433_k127_103755_0	1380390.JIAT01000010_gene4114	1.781e-179	574.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CU29@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_103755_9	1122939.ATUD01000009_gene3099	6.666e-55	196.0	COG1959@1|root,COG1959@2|Bacteria,2HQP9@201174|Actinobacteria,4CSAH@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158433_k127_103755_4	469383.Cwoe_5398	2.52e-119	396.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CPSF@84995|Rubrobacteria	84995|Rubrobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158433_k127_103755_3	1382306.JNIM01000001_gene4003	1.508e-142	471.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158433_k127_103755_11	1380390.JIAT01000011_gene2648	1.807e-48	188.0	COG2949@1|root,COG2949@2|Bacteria,2GWVK@201174|Actinobacteria,4CQSA@84995|Rubrobacteria	84995|Rubrobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158433_k127_103755_12	1122939.ATUD01000009_gene3112	6.791e-46	169.0	COG0822@1|root,COG0822@2|Bacteria,2HNZE@201174|Actinobacteria,4CQ8X@84995|Rubrobacteria	84995|Rubrobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158433_k127_1054929_7	1329516.JPST01000070_gene1945	1.938e-13	73.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes,4I01W@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1054929_2	469383.Cwoe_3541	6.467e-151	487.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CPR4@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158433_k127_1054929_0	469383.Cwoe_3542	1.498e-175	594.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158433_k127_1054929_4	469383.Cwoe_3543	2.233e-67	235.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4CQEI@84995|Rubrobacteria	84995|Rubrobacteria	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158433_k127_1054929_1	469383.Cwoe_3544	5.532e-165	537.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CP8S@84995|Rubrobacteria	84995|Rubrobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158433_k127_1054929_5	1122939.ATUD01000004_gene3943	4.285e-61	216.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CR4P@84995|Rubrobacteria	84995|Rubrobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158433_k127_1054929_6	469383.Cwoe_3545	3.816e-57	207.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CR4P@84995|Rubrobacteria	84995|Rubrobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158433_k127_1054929_3	469383.Cwoe_3546	2.807e-118	387.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CPIA@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158433_k127_1093446_1	469383.Cwoe_4211	2.476e-200	629.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158433_k127_1093446_5	927677.ALVU02000001_gene3553	9.33e-79	284.0	COG3664@1|root,COG3664@2|Bacteria,1GQP6@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1093446_6	927677.ALVU02000001_gene3553	6.13e-75	274.0	COG3664@1|root,COG3664@2|Bacteria,1GQP6@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1093446_2	1283299.AUKG01000002_gene4336	5.141e-192	603.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CPSD@84995|Rubrobacteria	84995|Rubrobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158433_k127_1093446_12	469383.Cwoe_2897	7.525e-13	76.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158433_k127_1093446_0	469383.Cwoe_4224	4.826e-209	656.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CP7A@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1093446_9	1380390.JIAT01000010_gene3548	2.714e-19	93.0	2BF3V@1|root,328W1@2|Bacteria,2HPA5@201174|Actinobacteria,4CQNE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1093446_13	1238184.CM001792_gene2715	8.963e-12	75.0	COG0463@1|root,COG3115@1|root,COG0463@2|Bacteria,COG3115@2|Bacteria,1TQEM@1239|Firmicutes,4H9X9@91061|Bacilli,23K37@182709|Oceanobacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
SRR25158433_k127_1093446_11	671143.DAMO_0300	3.468e-13	83.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,SprB,VPEP,fn3
SRR25158433_k127_1093446_8	204669.Acid345_3809	4.183e-40	163.0	COG0241@1|root,COG0241@2|Bacteria,3Y5QH@57723|Acidobacteria,2JJXK@204432|Acidobacteriia	204432|Acidobacteriia	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR25158433_k127_1093446_7	592015.HMPREF1705_00546	3.904e-49	182.0	COG0279@1|root,COG0279@2|Bacteria,3TB1U@508458|Synergistetes	508458|Synergistetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158433_k127_1093446_3	592015.HMPREF1705_00545	2.143e-122	411.0	COG2605@1|root,COG2605@2|Bacteria,3TC8T@508458|Synergistetes	508458|Synergistetes	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158433_k127_1093446_4	469383.Cwoe_4212	2.719e-94	311.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CQDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158433_k127_1100273_6	1380390.JIAT01000009_gene1950	4.646e-39	151.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CP8W@84995|Rubrobacteria	84995|Rubrobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158433_k127_1100273_7	1380390.JIAT01000009_gene1949	2.983e-27	124.0	COG0671@1|root,COG0671@2|Bacteria,2IIA1@201174|Actinobacteria,4CQUT@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158433_k127_1100273_3	290397.Adeh_1214	1.908e-60	221.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,42RB3@68525|delta/epsilon subdivisions,2WMW4@28221|Deltaproteobacteria,2Z183@29|Myxococcales	28221|Deltaproteobacteria	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
SRR25158433_k127_1100273_0	1283299.AUKG01000001_gene2083	4.331e-151	516.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1100273_2	42256.RradSPS_3150	7.517e-65	229.0	COG0500@1|root,COG2226@2|Bacteria,2IBEJ@201174|Actinobacteria	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR25158433_k127_1100273_4	1283299.AUKG01000001_gene1898	1.706e-54	194.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158433_k127_1100273_1	1283299.AUKG01000001_gene1889	4.017e-79	272.0	COG3872@1|root,COG3872@2|Bacteria,2HQG9@201174|Actinobacteria,4CS1C@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158433_k127_1100273_5	1380390.JIAT01000010_gene3508	3.569e-43	166.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158433_k127_1142015_19	469383.Cwoe_3760	2.066e-16	85.0	COG1487@1|root,COG1487@2|Bacteria,2IRPF@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_1142015_15	1394178.AWOO02000004_gene2428	1.776e-30	137.0	COG3118@1|root,COG3118@2|Bacteria,2I35R@201174|Actinobacteria	201174|Actinobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
SRR25158433_k127_1142015_22	929712.KI912613_gene1092	0.0008437	50.0	2AW9W@1|root,31N5B@2|Bacteria,2HQT5@201174|Actinobacteria,4CSHX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1142015_12	469383.Cwoe_5921	4.133e-68	240.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CP82@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158433_k127_1142015_20	469383.Cwoe_5922	7.919e-13	71.0	COG1826@1|root,COG1826@2|Bacteria,2HRTJ@201174|Actinobacteria,4CTX0@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158433_k127_1142015_7	469383.Cwoe_5924	3.413e-95	329.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CQGP@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
SRR25158433_k127_1142015_8	1380390.JIAT01000009_gene1822	8.889e-93	310.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158433_k127_1142015_11	469383.Cwoe_5926	2.814e-82	297.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
SRR25158433_k127_1142015_4	469383.Cwoe_5927	9.036e-113	377.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CQ40@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR25158433_k127_1142015_14	469383.Cwoe_5928	2.289e-64	233.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria,4CQW0@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158433_k127_1142015_1	469383.Cwoe_1710	5.267e-154	535.0	COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,2HGJ9@201174|Actinobacteria,4CRYN@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_1142015_18	469383.Cwoe_5929	7.549e-20	104.0	2AWJ7@1|root,31NFU@2|Bacteria,2HR1C@201174|Actinobacteria,4CSVI@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1142015_0	469383.Cwoe_5930	4.314e-174	565.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CPG9@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158433_k127_1142015_2	469383.Cwoe_5931	1.295e-148	495.0	COG1522@1|root,COG1522@2|Bacteria,2IIXK@201174|Actinobacteria,4CPCF@84995|Rubrobacteria	84995|Rubrobacteria	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
SRR25158433_k127_1142015_3	264732.Moth_1246	2.339e-137	443.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
SRR25158433_k127_1142015_10	1283299.AUKG01000001_gene1784	1.815e-83	284.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4CRAH@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158433_k127_1142015_6	1380390.JIAT01000009_gene1813	2.487e-101	351.0	COG1668@1|root,COG1668@2|Bacteria,2HNDN@201174|Actinobacteria,4CP6Y@84995|Rubrobacteria	84995|Rubrobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158433_k127_1142015_16	929712.KI912613_gene2799	7.482e-27	127.0	2DP3D@1|root,330CN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1142015_9	469383.Cwoe_5935	2.357e-92	312.0	COG1692@1|root,COG1692@2|Bacteria,2IG59@201174|Actinobacteria,4CQ4Z@84995|Rubrobacteria	84995|Rubrobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158433_k127_1142015_13	261292.Nit79A3_3402	3.885e-66	239.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VQN2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158433_k127_1142015_21	1288079.AUKN01000003_gene3907	9.318e-09	67.0	COG1657@1|root,COG1657@2|Bacteria,2GIRK@201174|Actinobacteria	201174|Actinobacteria	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
SRR25158433_k127_1142015_5	469383.Cwoe_5936	4.031e-105	353.0	2AU3I@1|root,31JPZ@2|Bacteria,2H277@201174|Actinobacteria,4CQ2S@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1143803_27	1380390.JIAT01000014_gene6229	1.468e-14	86.0	COG4942@1|root,COG4942@2|Bacteria,2GP1Y@201174|Actinobacteria,4CPU0@84995|Rubrobacteria	84995|Rubrobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158433_k127_1143803_13	469383.Cwoe_2995	1.741e-61	221.0	COG0566@1|root,COG0566@2|Bacteria,2GJ7P@201174|Actinobacteria	201174|Actinobacteria	J	SpoU rRNA Methylase family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158433_k127_1143803_20	929712.KI912613_gene2168	8.273e-54	192.0	COG0346@1|root,COG0346@2|Bacteria,2IIM8@201174|Actinobacteria,4CQQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158433_k127_1143803_33	469383.Cwoe_2474	6.978e-09	66.0	COG1361@1|root,COG1361@2|Bacteria,2HF4Q@201174|Actinobacteria,4CRIC@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158433_k127_1143803_29	439497.RR11_3176	8.766e-11	72.0	COG2931@1|root,COG2931@2|Bacteria,1N161@1224|Proteobacteria,2UDXT@28211|Alphaproteobacteria,4NB39@97050|Ruegeria	28211|Alphaproteobacteria	Q	Type I secretion target repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158433_k127_1143803_18	469383.Cwoe_0900	5.909e-56	205.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4CT93@84995|Rubrobacteria	84995|Rubrobacteria	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158433_k127_1143803_2	469383.Cwoe_0899	2.616e-204	644.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CS9X@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158433_k127_1143803_25	1382306.JNIM01000001_gene3144	4.829e-32	128.0	COG1324@1|root,COG1324@2|Bacteria,2G76K@200795|Chloroflexi	200795|Chloroflexi	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158433_k127_1143803_7	69395.JQLZ01000004_gene536	1.262e-111	383.0	COG1404@1|root,COG1404@2|Bacteria,1R5Y1@1224|Proteobacteria,2U1X6@28211|Alphaproteobacteria,2KGM7@204458|Caulobacterales	204458|Caulobacterales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158433_k127_1143803_12	316056.RPC_1793	7.497e-65	241.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,2U7SC@28211|Alphaproteobacteria,3K57D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_1143803_5	1380390.JIAT01000010_gene4557	5.486e-125	409.0	COG0842@1|root,COG0842@2|Bacteria,2ICWC@201174|Actinobacteria,4CS9I@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158433_k127_1143803_6	1380390.JIAT01000010_gene4556	2.261e-119	408.0	COG1131@1|root,COG1131@2|Bacteria,2IBZE@201174|Actinobacteria,4CPJZ@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158433_k127_1143803_34	525368.HMPREF0591_3856	3.619e-08	65.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,23AQX@1762|Mycobacteriaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158433_k127_1143803_8	1283299.AUKG01000001_gene1927	4.424e-99	331.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4CQ1C@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158433_k127_1143803_14	469383.Cwoe_1599	2.226e-61	235.0	2DM8B@1|root,325JJ@2|Bacteria,2HF4F@201174|Actinobacteria,4CSFB@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
SRR25158433_k127_1143803_1	101510.RHA1_ro02919	2.17e-224	707.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4FVF3@85025|Nocardiaceae	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K10215	ko00627,ko01120,map00627,map01120	-	R07836,R07837	RC02100,RC03121	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,FMO-like,NAD_binding_8,Pyr_redox_2
SRR25158433_k127_1143803_9	595537.Varpa_3800	1.995e-83	281.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria,4ADRK@80864|Comamonadaceae	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158433_k127_1143803_21	469383.Cwoe_0387	2.054e-53	192.0	COG0346@1|root,COG0346@2|Bacteria,2HRG5@201174|Actinobacteria,4CTF6@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158433_k127_1143803_3	1283299.AUKG01000001_gene3440	1.044e-159	510.0	COG0604@1|root,COG0604@2|Bacteria,2I66C@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
SRR25158433_k127_1143803_39	1283299.AUKG01000004_gene888	5.266e-05	55.0	COG2931@1|root,COG2931@2|Bacteria,2IGYS@201174|Actinobacteria,4CSAT@84995|Rubrobacteria	84995|Rubrobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158433_k127_1143803_32	744979.R2A130_2076	4.176e-09	66.0	COG2911@1|root,COG2931@1|root,COG4932@1|root,COG5295@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,HCBP_related,He_PIG,HemolysinCabind
SRR25158433_k127_1143803_24	1996.JOFO01000004_gene3615	1.895e-48	184.0	2A1WW@1|root,30Q6B@2|Bacteria,2HGNT@201174|Actinobacteria,4EKVI@85012|Streptosporangiales	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158433_k127_1143803_17	405948.SACE_5547	3.389e-57	207.0	COG0668@1|root,COG0668@2|Bacteria,2HD92@201174|Actinobacteria,4E0HQ@85010|Pseudonocardiales	201174|Actinobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
SRR25158433_k127_1143803_35	1121926.AXWO01000005_gene413	4.08e-08	59.0	2EK4V@1|root,33DVA@2|Bacteria,2GX4X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1143803_15	42256.RradSPS_2206	5.812e-61	233.0	2EDR5@1|root,32UKZ@2|Bacteria,2ID1D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1143803_19	67257.JODR01000005_gene2157	2.241e-54	200.0	COG5412@1|root,COG5412@2|Bacteria	2|Bacteria	N	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
SRR25158433_k127_1143803_23	1380390.JIAT01000015_gene5878	7.15e-50	194.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria	201174|Actinobacteria	D	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158433_k127_1143803_22	42256.RradSPS_2813	6.691e-52	192.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4CR3N@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158433_k127_1143803_30	656024.FsymDg_2242	1.047e-10	69.0	COG1813@1|root,COG1813@2|Bacteria,2I3XR@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158433_k127_1143803_37	911045.PSE_0358	4.154e-06	56.0	COG3440@1|root,COG3440@2|Bacteria,1NHIB@1224|Proteobacteria,2TT95@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Domain of unknown function (DUF3883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883
SRR25158433_k127_1143803_16	357809.Cphy_2922	2.379e-59	229.0	COG0553@1|root,COG0553@2|Bacteria,1UFS1@1239|Firmicutes,24IZP@186801|Clostridia	186801|Clostridia	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
SRR25158433_k127_1143803_38	278197.PEPE_0534	1.263e-05	57.0	COG1475@1|root,COG1475@2|Bacteria,1U5BV@1239|Firmicutes,4HC81@91061|Bacilli,3F5ZJ@33958|Lactobacillaceae	91061|Bacilli	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158433_k127_1143803_10	481448.Minf_0320	5.633e-74	274.0	COG1743@1|root,COG1743@2|Bacteria,46W8J@74201|Verrucomicrobia	74201|Verrucomicrobia	H	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR25158433_k127_1143803_28	693661.Arcve_0735	2.985e-11	66.0	arCOG03086@1|root,arCOG03086@2157|Archaea,2Y6GQ@28890|Euryarchaeota,247DW@183980|Archaeoglobi	183980|Archaeoglobi	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158433_k127_1143803_31	679926.Mpet_0477	5.974e-10	62.0	COG1598@1|root,arCOG02411@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158433_k127_1143803_11	1032480.MLP_01000	3.953e-70	268.0	COG0457@1|root,COG0457@2|Bacteria,2GIWN@201174|Actinobacteria,4DW93@85009|Propionibacteriales	201174|Actinobacteria	S	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_4
SRR25158433_k127_1143803_26	1121440.AUMA01000006_gene1636	2.344e-27	121.0	2AIEX@1|root,318WD@2|Bacteria,1Q12P@1224|Proteobacteria,43EUP@68525|delta/epsilon subdivisions,2X1TI@28221|Deltaproteobacteria,2MFNH@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1143803_4	42256.RradSPS_0484	9.568e-134	439.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4CP9V@84995|Rubrobacteria	84995|Rubrobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
SRR25158433_k127_1143803_0	134676.ACPL_5842	9.972e-307	994.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
SRR25158433_k127_115105_7	1283299.AUKG01000002_gene4923	1.938e-62	224.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158433_k127_115105_4	469383.Cwoe_3517	2.881e-96	329.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CQ0Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158433_k127_115105_8	469383.Cwoe_3516	1.22e-60	215.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CQ46@84995|Rubrobacteria	84995|Rubrobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158433_k127_115105_2	1380390.JIAT01000010_gene4534	4.306e-107	360.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CPH9@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158433_k127_115105_5	469383.Cwoe_3514	6.272e-73	251.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CQ2J@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158433_k127_115105_3	1380390.JIAT01000010_gene4536	1.75e-104	347.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158433_k127_115105_6	469383.Cwoe_3512	4.296e-72	254.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CQ05@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158433_k127_115105_0	469383.Cwoe_3510	1.964e-140	473.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CPQ0@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158433_k127_115105_1	1380390.JIAT01000010_gene4549	2.183e-113	389.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CPEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158433_k127_115105_11	1048339.KB913029_gene2077	3.773e-14	85.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM9_1,CHB_HEX_C_1,CarboxypepD_reg,DUF11,Kelch_1,NPCBM_assoc,OmpA,Pectate_lyase_3,SLH,VCBS
SRR25158433_k127_115105_10	1300345.LF41_1325	4.921e-30	136.0	COG2931@1|root,COG2931@2|Bacteria,1R30G@1224|Proteobacteria,1T60T@1236|Gammaproteobacteria,1XDH4@135614|Xanthomonadales	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.4.24.40	ko:K01406,ko:K07004	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,VCBS
SRR25158433_k127_115105_9	1380390.JIAT01000014_gene6303	8.477e-51	191.0	COG2885@1|root,COG2885@2|Bacteria,2HENQ@201174|Actinobacteria,4CQR9@84995|Rubrobacteria	84995|Rubrobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2
SRR25158433_k127_1169815_4	66377.JOBH01000006_gene216	4.895e-07	55.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158433_k127_1169815_0	1283299.AUKG01000003_gene233	4.268e-63	235.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
SRR25158433_k127_1169815_2	1223543.GP2_052_00210	3.482e-18	93.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4GCXC@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158433_k127_1169815_5	1198114.AciX9_1310	1.187e-05	56.0	COG4914@1|root,COG4914@2|Bacteria,3Y9D7@57723|Acidobacteria,2JNAR@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1169815_3	1304865.JAGF01000001_gene1440	2.787e-12	71.0	COG1669@1|root,COG1669@2|Bacteria,2GR6M@201174|Actinobacteria	201174|Actinobacteria	K	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,NTP_transf_2
SRR25158433_k127_1169815_1	1380390.JIAT01000009_gene1220	1.829e-60	218.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CP81@84995|Rubrobacteria	84995|Rubrobacteria	L	DbpA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DbpA,Helicase_C
SRR25158433_k127_1172652_2	1380390.JIAT01000010_gene4500	3.212e-77	266.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CPIA@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158433_k127_1172652_1	1380390.JIAT01000010_gene4499	4.183e-139	449.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158433_k127_1172652_0	469383.Cwoe_3548	1.69e-140	454.0	COG0473@1|root,COG0473@2|Bacteria,2HABY@201174|Actinobacteria,4CPBV@84995|Rubrobacteria	84995|Rubrobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158433_k127_1199412_30	469383.Cwoe_3778	1.519e-27	118.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4CQT3@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158433_k127_1199412_12	469383.Cwoe_3777	4.978e-123	405.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CPWG@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158433_k127_1199412_2	469383.Cwoe_3775	6.804e-170	549.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CPGN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158433_k127_1199412_4	469383.Cwoe_3774	1.536e-150	509.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CP75@84995|Rubrobacteria	84995|Rubrobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158433_k127_1199412_16	1380390.JIAT01000010_gene4142	2.648e-104	355.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CPND@84995|Rubrobacteria	84995|Rubrobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158433_k127_1199412_7	469383.Cwoe_3773	8.602e-142	462.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CPF5@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158433_k127_1199412_6	1380390.JIAT01000010_gene4145	3.205e-142	466.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158433_k127_1199412_19	929712.KI912613_gene3339	9.306e-80	292.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CPQK@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158433_k127_1199412_15	469383.Cwoe_3770	2.07e-105	354.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CPNI@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158433_k127_1199412_18	561175.KB894098_gene5395	2.775e-95	330.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4EG2K@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158433_k127_1199412_24	1089551.KE386572_gene1786	1.149e-59	217.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,4BPPJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158433_k127_1199412_31	1380390.JIAT01000010_gene4150	2.691e-11	72.0	COG1589@1|root,COG1589@2|Bacteria,2HPRM@201174|Actinobacteria,4CR4Y@84995|Rubrobacteria	84995|Rubrobacteria	M	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158433_k127_1199412_3	1380390.JIAT01000010_gene4151	3.96e-157	504.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CP7W@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158433_k127_1199412_9	929712.KI912613_gene3345	1.054e-137	447.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CP79@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158433_k127_1199412_25	1380390.JIAT01000010_gene4157	1.706e-53	191.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158433_k127_1199412_1	469383.Cwoe_3754	2.487e-193	613.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CP8Z@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158433_k127_1199412_0	469383.Cwoe_3753	4.773e-238	744.0	COG1003@1|root,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4CPH8@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
SRR25158433_k127_1199412_32	357808.RoseRS_2986	2.777e-10	75.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
SRR25158433_k127_1199412_28	469383.Cwoe_5343	8.96e-45	188.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4842,DUF5122
SRR25158433_k127_1199412_11	1283299.AUKG01000001_gene1590	3.768e-128	445.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1199412_14	204669.Acid345_2863	1.787e-116	381.0	COG3285@1|root,COG3285@2|Bacteria,3Y637@57723|Acidobacteria,2JM9H@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158433_k127_1199412_20	469383.Cwoe_1814	8.092e-77	268.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158433_k127_1199412_27	1120950.KB892766_gene5113	7.762e-46	173.0	COG1117@1|root,COG1117@2|Bacteria,2ID49@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	pstB	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
SRR25158433_k127_1199412_26	1183438.GKIL_2541	1.074e-49	190.0	COG0390@1|root,COG0390@2|Bacteria,1G1TY@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0014)	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158433_k127_1199412_8	469383.Cwoe_0976	9.202e-142	468.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CPQ3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_1199412_10	1380390.JIAT01000010_gene4164	1.832e-136	441.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CPN5@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158433_k127_1199412_22	469383.Cwoe_3747	2.899e-70	245.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4CQNN@84995|Rubrobacteria	84995|Rubrobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158433_k127_1199412_23	1380390.JIAT01000010_gene4166	4.003e-64	229.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CPY7@84995|Rubrobacteria	84995|Rubrobacteria	K	Segregation and condensation complex subunit ScpB	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158433_k127_1199412_21	469383.Cwoe_3744	1.602e-70	246.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CQ72@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158433_k127_1199412_29	469383.Cwoe_3742	4.846e-39	151.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,4CQE6@84995|Rubrobacteria	84995|Rubrobacteria	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158433_k127_1199412_13	1283299.AUKG01000002_gene4647	1.033e-117	391.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,4CPIS@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158433_k127_1199412_5	469383.Cwoe_4999	7.757e-147	477.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CSEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158433_k127_1199412_17	469383.Cwoe_3737	8.418e-100	344.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158433_k127_1207096_3	469383.Cwoe_1561	1.792e-06	50.0	COG4262@1|root,COG4262@2|Bacteria,2HNDH@201174|Actinobacteria,4CP6G@84995|Rubrobacteria	84995|Rubrobacteria	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158433_k127_1207096_0	469383.Cwoe_2647	3.294e-122	407.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CPX5@84995|Rubrobacteria	84995|Rubrobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158433_k127_1207096_2	1121406.JAEX01000001_gene518	1.165e-56	214.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S7S@68525|delta/epsilon subdivisions,2WNFR@28221|Deltaproteobacteria,2M9XW@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRR25158433_k127_1207096_1	469383.Cwoe_2648	3.261e-61	217.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158433_k127_1223273_4	1283299.AUKG01000001_gene2737	7.694e-196	617.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4CR7S@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
SRR25158433_k127_1223273_30	469383.Cwoe_3621	1.08e-66	241.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4CQHG@84995|Rubrobacteria	84995|Rubrobacteria	G	glycoside hydrolase, family	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158433_k127_1223273_33	42256.RradSPS_1169	4.878e-60	214.0	COG0122@1|root,COG0122@2|Bacteria,2HGA7@201174|Actinobacteria,4CQF8@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158433_k127_1223273_22	1380390.JIAT01000011_gene2677	4.17e-80	279.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4CPUH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158433_k127_1223273_42	469383.Cwoe_1576	2.49e-25	117.0	COG4770@1|root,COG4770@2|Bacteria,2I2DF@201174|Actinobacteria	201174|Actinobacteria	I	biotin lipoyl attachment domain-containing protein	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158433_k127_1223273_28	469383.Cwoe_1577	5.333e-69	241.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_1223273_36	1121946.AUAX01000016_gene4819	3.518e-46	178.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria,4DEYR@85008|Micromonosporales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_1223273_3	1283299.AUKG01000001_gene2410	1.372e-206	653.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CPBQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158433_k127_1223273_21	1380390.JIAT01000011_gene2679	1.84e-80	275.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,4CP9N@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158433_k127_1223273_29	469383.Cwoe_1580	5.679e-68	241.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gumP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_1223273_17	929712.KI912613_gene2136	3.607e-99	332.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4CRTV@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
SRR25158433_k127_1223273_34	414996.IL38_10520	1.406e-51	190.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Putative_PNPOx
SRR25158433_k127_1223273_13	1380390.JIAT01000011_gene2688	2.398e-116	382.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4CPAT@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158433_k127_1223273_19	1448389.BAVQ01000002_gene2863	5.066e-85	287.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158433_k127_1223273_41	118161.KB235922_gene3441	3.2e-27	122.0	COG0454@1|root,COG0456@2|Bacteria,1GGD2@1117|Cyanobacteria	1117|Cyanobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1223273_49	1236902.ANAS01000030_gene3013	1.659e-11	71.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4EK6F@85012|Streptosporangiales	201174|Actinobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158433_k127_1223273_35	1449058.JQKT01000007_gene1628	1.852e-49	179.0	COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria,4FQ8Z@85023|Microbacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158433_k127_1223273_40	1297863.APJF01000021_gene127	1.816e-27	124.0	COG4861@1|root,COG4861@2|Bacteria,1QEX3@1224|Proteobacteria,2U1Y0@28211|Alphaproteobacteria,3K5QZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2,MarR_2
SRR25158433_k127_1223273_32	1340493.JNIF01000004_gene1135	9.99e-62	222.0	2DH2J@1|root,2ZY63@2|Bacteria,3Y8TF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1223273_10	1144275.COCOR_04995	1.565e-133	439.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42Q1R@68525|delta/epsilon subdivisions,2WM4U@28221|Deltaproteobacteria,2YWW8@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249,ko:K11731	ko00071,ko00280,ko00281,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00281,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R08089	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1223273_44	1283299.AUKG01000001_gene3315	3.811e-20	102.0	COG3631@1|root,COG3631@2|Bacteria,2IGEH@201174|Actinobacteria,4CR0V@84995|Rubrobacteria	84995|Rubrobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158433_k127_1223273_7	1122939.ATUD01000003_gene3637	8.391e-175	557.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria,4CRXS@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1223273_15	1283299.AUKG01000001_gene2765	1.006e-104	346.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CPTH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158433_k127_1223273_1	469383.Cwoe_1593	1.009e-244	770.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158433_k127_1223273_9	469383.Cwoe_1594	8.369e-146	469.0	COG3246@1|root,COG3246@2|Bacteria,2I9EQ@201174|Actinobacteria,4CT4T@84995|Rubrobacteria	84995|Rubrobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158433_k127_1223273_8	469383.Cwoe_1595	1.186e-172	553.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4CU2K@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158433_k127_1223273_24	469383.Cwoe_1596	4.73e-78	273.0	COG0789@1|root,COG0789@2|Bacteria,2HPW7@201174|Actinobacteria,4CRAT@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158433_k127_1223273_14	1068980.ARVW01000001_gene7376	3.038e-115	380.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4E213@85010|Pseudonocardiales	201174|Actinobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
SRR25158433_k127_1223273_20	221288.JH992901_gene4418	2.447e-83	285.0	COG4221@1|root,COG4221@2|Bacteria,1GHFE@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_1223273_5	469383.Cwoe_0601	1.331e-186	620.0	COG2114@1|root,COG2909@1|root,COG3899@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc
SRR25158433_k127_1223273_16	469383.Cwoe_1600	8.799e-102	339.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4CPAW@84995|Rubrobacteria	84995|Rubrobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158433_k127_1223273_25	1380390.JIAT01000011_gene2726	6.729e-78	276.0	COG1309@1|root,COG1309@2|Bacteria,2IEV2@201174|Actinobacteria,4CPWP@84995|Rubrobacteria	84995|Rubrobacteria	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
SRR25158433_k127_1223273_50	1380390.JIAT01000011_gene2727	1.989e-11	65.0	2A5U7@1|root,31PFR@2|Bacteria,2HRV2@201174|Actinobacteria,4CTYF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1223273_45	1283299.AUKG01000001_gene2794	1.912e-19	95.0	2AWHM@1|root,31NE6@2|Bacteria,2HR07@201174|Actinobacteria,4CSTU@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158433_k127_1223273_48	1283299.AUKG01000001_gene2795	2.006e-13	79.0	2AUM4@1|root,31K9W@2|Bacteria,2HP6Z@201174|Actinobacteria,4CQJ3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158433_k127_1223273_18	1283299.AUKG01000001_gene2797	7.636e-91	307.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CPTV@84995|Rubrobacteria	84995|Rubrobacteria	S	TIGRFAM degV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158433_k127_1223273_39	469383.Cwoe_1612	2.042e-29	133.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CQFF@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158433_k127_1223273_43	3880.AES84528	7.471e-24	105.0	COG0278@1|root,KOG0911@2759|Eukaryota,37HP0@33090|Viridiplantae,3G9FW@35493|Streptophyta,4JE5S@91835|fabids	35493|Streptophyta	O	Monothiol	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009914,GO:0009926,GO:0009987,GO:0010817,GO:0033554,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0051726,GO:0060918,GO:0065007,GO:0065008,GO:0072593	-	-	-	-	-	-	-	-	-	-	Glutaredoxin,Thioredoxin
SRR25158433_k127_1223273_47	1173020.Cha6605_5761	6.193e-15	77.0	COG0271@1|root,COG0271@2|Bacteria,1G7V3@1117|Cyanobacteria	1117|Cyanobacteria	T	Belongs to the BolA IbaG family	colA	-	-	-	-	-	-	-	-	-	-	-	BolA
SRR25158433_k127_1223273_6	469383.Cwoe_4411	1.346e-177	568.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CSBR@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158433_k127_1223273_46	1121374.KB891587_gene3009	5.472e-17	87.0	2EB79@1|root,318GM@2|Bacteria,1Q0C2@1224|Proteobacteria,1SV7C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1223273_23	1380390.JIAT01000011_gene2743	3.665e-78	272.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4CQB7@84995|Rubrobacteria	84995|Rubrobacteria	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158433_k127_1223273_38	469383.Cwoe_5454	5.943e-33	144.0	COG3119@1|root,COG3119@2|Bacteria,2HRVJ@201174|Actinobacteria,4CTZ0@84995|Rubrobacteria	84995|Rubrobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1223273_51	1121481.AUAS01000008_gene3120	9.369e-09	67.0	COG4372@1|root,COG4372@2|Bacteria,4PABY@976|Bacteroidetes,47T6B@768503|Cytophagia	976|Bacteroidetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1223273_2	469383.Cwoe_1613	3.913e-244	776.0	COG0392@1|root,COG0438@1|root,COG0392@2|Bacteria,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CPA3@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,LPG_synthase_TM
SRR25158433_k127_1223273_53	479433.Caci_4357	0.0002961	52.0	COG1846@1|root,COG1846@2|Bacteria,2IN55@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
SRR25158433_k127_1223273_0	469383.Cwoe_1617	0.0	1863.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CPS6@84995|Rubrobacteria	84995|Rubrobacteria	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158433_k127_1223273_26	1380390.JIAT01000009_gene745	8.597e-75	259.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CPR6@84995|Rubrobacteria	84995|Rubrobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158433_k127_1223273_27	469383.Cwoe_5257	3.325e-69	247.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158433_k127_1223273_31	469383.Cwoe_5256	1.108e-63	228.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CQ1I@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158433_k127_1223273_11	1283299.AUKG01000003_gene562	6.483e-120	407.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2GKGR@201174|Actinobacteria,4CU5U@84995|Rubrobacteria	84995|Rubrobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,SNARE_assoc
SRR25158433_k127_1223273_12	1380390.JIAT01000009_gene740	2.179e-119	396.0	COG2508@1|root,COG2508@2|Bacteria,2HJJI@201174|Actinobacteria,4CPT6@84995|Rubrobacteria	84995|Rubrobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158433_k127_1223273_37	469383.Cwoe_5837	3.442e-38	151.0	COG3247@1|root,COG3247@2|Bacteria	2|Bacteria	U	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158433_k127_1233812_28	1380390.JIAT01000010_gene4222	2.977e-26	110.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CPUZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158433_k127_1233812_2	469383.Cwoe_3701	8.294e-185	606.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CPM1@84995|Rubrobacteria	84995|Rubrobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158433_k127_1233812_26	1283299.AUKG01000002_gene4707	5.106e-37	157.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CQ9U@84995|Rubrobacteria	84995|Rubrobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158433_k127_1233812_20	469383.Cwoe_3699	1.829e-64	227.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CQ3G@84995|Rubrobacteria	84995|Rubrobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158433_k127_1233812_15	469383.Cwoe_3698	5.008e-73	248.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1233812_30	710111.FraQA3DRAFT_4933	3.491e-23	107.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158433_k127_1233812_23	469383.Cwoe_3693	2.307e-50	184.0	COG1399@1|root,COG1399@2|Bacteria,2HQSM@201174|Actinobacteria,4CSGR@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158433_k127_1233812_33	469383.Cwoe_3692	1.841e-16	86.0	COG0333@1|root,COG0333@2|Bacteria,2HPDQ@201174|Actinobacteria,4CQRN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158433_k127_1233812_12	469383.Cwoe_3691	3.98e-79	276.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CQB5@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158433_k127_1233812_31	1380390.JIAT01000010_gene4247	1.09e-22	104.0	COG0236@1|root,COG0236@2|Bacteria,2HNF1@201174|Actinobacteria,4CQR2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158433_k127_1233812_24	1380390.JIAT01000010_gene4248	3.155e-46	178.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CPZ4@84995|Rubrobacteria	84995|Rubrobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158433_k127_1233812_3	469383.Cwoe_3688	1.79e-173	584.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158433_k127_1233812_6	1380390.JIAT01000010_gene4252	1.567e-130	424.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CPF9@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158433_k127_1233812_4	572479.Hprae_0917	1.575e-156	506.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WAIA@53433|Halanaerobiales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158433_k127_1233812_27	469383.Cwoe_3682	3.093e-29	119.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CQNJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158433_k127_1233812_32	1283299.AUKG01000002_gene4749	9.552e-19	92.0	COG1837@1|root,COG1837@2|Bacteria,2HNEK@201174|Actinobacteria,4CQQV@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158433_k127_1233812_11	1122939.ATUD01000004_gene3804	4.644e-80	274.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CPQ4@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158433_k127_1233812_22	929712.KI912613_gene4187	6.578e-54	196.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CQ3H@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158433_k127_1233812_14	1380390.JIAT01000010_gene4262	1.206e-76	262.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158433_k127_1233812_13	469383.Cwoe_3676	9.736e-78	267.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CQ01@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158433_k127_1233812_29	1380390.JIAT01000010_gene4264	1.486e-23	106.0	COG0792@1|root,COG0792@2|Bacteria,2HP2Y@201174|Actinobacteria,4CQE0@84995|Rubrobacteria	84995|Rubrobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158433_k127_1233812_5	1121430.JMLG01000031_gene1635	2.674e-138	459.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,260SA@186807|Peptococcaceae	186801|Clostridia	O	PFAM magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158433_k127_1233812_19	469383.Cwoe_3673	3.397e-68	245.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CQDE@84995|Rubrobacteria	84995|Rubrobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158433_k127_1233812_17	42256.RradSPS_2433	3.223e-69	243.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CQ3U@84995|Rubrobacteria	84995|Rubrobacteria	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR25158433_k127_1233812_0	1380390.JIAT01000010_gene4273	2.083e-234	737.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CPCE@84995|Rubrobacteria	84995|Rubrobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158433_k127_1233812_18	469383.Cwoe_3668	1.903e-68	244.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4CTEF@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1233812_21	797209.ZOD2009_21607	1.89e-60	218.0	COG0212@1|root,arCOG00474@2157|Archaea,2XTN7@28890|Euryarchaeota,23S39@183963|Halobacteria	183963|Halobacteria	H	5-formyltetrahydrofolate cycloligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158433_k127_1233812_9	469383.Cwoe_3666	1.475e-99	335.0	COG1376@1|root,COG1376@2|Bacteria,2HPTN@201174|Actinobacteria,4CR7H@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158433_k127_1233812_8	1283299.AUKG01000002_gene4772	6.705e-101	336.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CSHN@84995|Rubrobacteria	84995|Rubrobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158433_k127_1233812_7	1283299.AUKG01000002_gene4773	2.434e-112	367.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158433_k127_1233812_1	555088.DealDRAFT_2165	1.877e-197	636.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42JHA@68298|Syntrophomonadaceae	186801|Clostridia	J	elongation factor Tu domain 2 protein	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158433_k127_1233812_35	469383.Cwoe_3662	3.012e-14	79.0	2AT5U@1|root,31IN3@2|Bacteria,2HN2Z@201174|Actinobacteria,4CQH5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1233812_25	469383.Cwoe_3660	2.83e-43	173.0	COG0328@1|root,COG0328@2|Bacteria,2I4IN@201174|Actinobacteria	201174|Actinobacteria	L	Reverse transcriptase-like	-	-	3.1.26.4,3.1.3.73	ko:K03469,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Glyoxalase_4,His_Phos_1,RVT_3
SRR25158433_k127_1233812_16	670292.JH26_23565	2.626e-69	250.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,1JUR8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158433_k127_1233812_34	1160137.KB907307_gene1438	1.7e-15	89.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria,4G5TG@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158433_k127_1233812_37	1444711.CCJF01000004_gene2090	8.202e-07	59.0	2EF0P@1|root,338TT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1233812_10	469383.Cwoe_2018	2.97e-82	289.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4CQMR@84995|Rubrobacteria	84995|Rubrobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158433_k127_1234345_1	469383.Cwoe_0661	6.144e-117	389.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	natB	-	-	ko:K01999,ko:K11954	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ANF_receptor,Peripla_BP_6
SRR25158433_k127_1234345_0	1283299.AUKG01000001_gene1590	6.112e-135	473.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1234345_2	1283299.AUKG01000001_gene1591	1.619e-45	191.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158433_k127_1234345_4	511051.CSE_15450	4.038e-14	87.0	COG1470@1|root,COG3391@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_6,Cu_amine_oxidN1,DUF4384,DUF5128,F5_F8_type_C,NHL
SRR25158433_k127_1234345_3	1440053.JOEI01000027_gene2996	3.161e-28	120.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158433_k127_1235680_11	469383.Cwoe_5862	7.56e-107	353.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CP8W@84995|Rubrobacteria	84995|Rubrobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158433_k127_1235680_10	469383.Cwoe_4154	3.943e-109	362.0	2CDI5@1|root,2Z7ZQ@2|Bacteria,2I8FG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1235680_15	1283299.AUKG01000001_gene1932	1.448e-72	259.0	COG2385@1|root,COG2385@2|Bacteria,2ID9T@201174|Actinobacteria,4CPMQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158433_k127_1235680_7	471852.Tcur_0327	3.63e-167	538.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EHQQ@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158433_k127_1235680_13	1120936.KB907209_gene1861	6.194e-79	287.0	COG1409@1|root,COG1409@2|Bacteria,2GK31@201174|Actinobacteria,4EMTH@85012|Streptosporangiales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158433_k127_1235680_6	1122939.ATUD01000014_gene1067	2.978e-175	565.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CPK3@84995|Rubrobacteria	84995|Rubrobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158433_k127_1235680_24	1380390.JIAT01000012_gene3304	8.651e-28	123.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4CU47@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158433_k127_1235680_5	253839.SSNG_06088	2.267e-175	565.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158433_k127_1235680_1	114615.BRADO2247	2.613e-316	994.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,3JUXZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
SRR25158433_k127_1235680_14	585531.HMPREF0063_11968	7.338e-78	270.0	COG0300@1|root,COG0300@2|Bacteria,2I2PB@201174|Actinobacteria,4DUTZ@85009|Propionibacteriales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_1235680_0	469383.Cwoe_5846	0.0	1292.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158433_k127_1235680_30	370438.PTH_1705	1.698e-07	57.0	COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,24UYA@186801|Clostridia,26363@186807|Peptococcaceae	186801|Clostridia	G	TIGRFAM 4-oxalocrotonate tautomerase family enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158433_k127_1235680_18	1380390.JIAT01000009_gene1984	6.334e-49	176.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4CQED@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158433_k127_1235680_9	42256.RradSPS_0076	6.987e-137	454.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158433_k127_1235680_22	469383.Cwoe_5833	8.305e-31	128.0	2AUAQ@1|root,31JYC@2|Bacteria,2HNZD@201174|Actinobacteria,4CQ8V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1235680_17	929712.KI912613_gene939	3.268e-54	214.0	COG1877@1|root,COG1877@2|Bacteria,2HP2R@201174|Actinobacteria,4CQDQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158433_k127_1235680_23	1283299.AUKG01000001_gene1966	5.172e-30	133.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158433_k127_1235680_27	1122939.ATUD01000026_gene2811	1.152e-20	96.0	COG0730@1|root,COG0730@2|Bacteria,2HU3V@201174|Actinobacteria,4CTHN@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158433_k127_1235680_12	1283299.AUKG01000001_gene1973	1.989e-93	315.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158433_k127_1235680_4	469383.Cwoe_5824	3.713e-248	797.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158433_k127_1235680_16	469383.Cwoe_5823	1.786e-66	235.0	COG0483@1|root,COG0483@2|Bacteria,2HNNN@201174|Actinobacteria,4CPT9@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158433_k127_1235680_20	469383.Cwoe_1823	1.359e-39	163.0	COG1595@1|root,COG1595@2|Bacteria,2IJIK@201174|Actinobacteria,4CRT2@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158433_k127_1235680_8	469383.Cwoe_5517	1.158e-160	512.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,4CPD2@84995|Rubrobacteria	84995|Rubrobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158433_k127_1235680_3	1380390.JIAT01000009_gene2171	2.15e-252	793.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158433_k127_1235680_31	929704.Myrod_3056	1.997e-07	62.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Glucosaminidase,Laminin_G_3,SLH
SRR25158433_k127_1235680_2	1380390.JIAT01000009_gene2164	1.389e-291	903.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158433_k127_1235680_25	419947.MRA_2578	3.572e-27	119.0	COG2402@1|root,COG2402@2|Bacteria,2H9NW@201174|Actinobacteria	201174|Actinobacteria	S	toxic component of a	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158433_k127_1235680_26	469383.Cwoe_3167	4.854e-22	105.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1235680_21	469383.Cwoe_3152	2.665e-38	152.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1235680_29	469383.Cwoe_3167	4.092e-14	80.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1235680_19	469383.Cwoe_3152	7.789e-49	183.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1236115_19	1408254.T458_23090	1.248e-06	57.0	COG5263@1|root,COG5263@2|Bacteria,1VNIZ@1239|Firmicutes	1239|Firmicutes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
SRR25158433_k127_1236115_20	1283299.AUKG01000002_gene4835	0.0009561	48.0	2ATYS@1|root,31JIE@2|Bacteria,2HNQF@201174|Actinobacteria,4CQUF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1236115_1	469383.Cwoe_2604	1.091e-195	617.0	COG1373@1|root,COG1373@2|Bacteria,2GK4E@201174|Actinobacteria	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158433_k127_1236115_12	653045.Strvi_5838	1.399e-59	214.0	COG1028@1|root,COG1028@2|Bacteria,2GXKF@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_1236115_11	1380390.JIAT01000009_gene571	1.04e-74	259.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4CRRD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158433_k127_1236115_14	469383.Cwoe_3152	9.294e-34	139.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1236115_15	1380390.JIAT01000009_gene604	6.205e-33	137.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CSIJ@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1236115_17	469383.Cwoe_3152	1.476e-31	132.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1236115_7	1048339.KB913029_gene3712	1.567e-118	402.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158433_k127_1236115_13	631454.N177_3468	1.624e-58	223.0	28NR0@1|root,2ZBQD@2|Bacteria,1RA2I@1224|Proteobacteria,2U5BA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleoside 2-deoxyribosyltransferase YtoQ	ytoQ	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyri_tr3
SRR25158433_k127_1236115_0	469383.Cwoe_3251	1.378e-253	799.0	COG1372@1|root,COG1533@1|root,COG1372@2|Bacteria,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158433_k127_1236115_6	469383.Cwoe_5554	1.464e-121	405.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4CR2R@84995|Rubrobacteria	84995|Rubrobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158433_k127_1236115_2	1246448.ANAZ01000012_gene827	7.073e-169	548.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4EFHH@85012|Streptosporangiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158433_k127_1236115_4	350058.Mvan_0436	6.768e-139	464.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,236AR@1762|Mycobacteriaceae	201174|Actinobacteria	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158433_k127_1236115_5	1209984.BN978_03764	6.911e-130	424.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,23421@1762|Mycobacteriaceae	201174|Actinobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158433_k127_1236115_3	1209984.BN978_03765	2.411e-166	541.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,2370B@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158433_k127_1236115_10	1380390.JIAT01000011_gene2652	1.79e-91	317.0	COG0477@1|root,COG2814@2|Bacteria,2ID9K@201174|Actinobacteria,4CQJG@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_1236115_8	1380390.JIAT01000011_gene2651	7.156e-113	380.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4CR7M@84995|Rubrobacteria	84995|Rubrobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158433_k127_1236115_9	562970.Btus_1061	8.227e-94	319.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,278YF@186823|Alicyclobacillaceae	91061|Bacilli	E	Alcohol dehydrogenase GroES-associated	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158433_k127_1236115_18	469383.Cwoe_0707	3.787e-22	106.0	COG1725@1|root,COG1725@2|Bacteria	469383.Cwoe_0707|-	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1236115_16	929712.KI912613_gene4841	2.932e-32	139.0	COG0767@1|root,COG0767@2|Bacteria,2IAUN@201174|Actinobacteria,4CR2S@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158433_k127_1247201_0	469383.Cwoe_4763	5.73e-71	263.0	COG0226@1|root,COG0226@2|Bacteria,2HREN@201174|Actinobacteria,4CTD4@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1247201_1	1283299.AUKG01000003_gene456	3.189e-54	198.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CRP4@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158433_k127_1298453_7	324057.Pjdr2_1229	8.289e-22	112.0	COG2244@1|root,COG2244@2|Bacteria,1V8VR@1239|Firmicutes,4HNZI@91061|Bacilli,26T7A@186822|Paenibacillaceae	91061|Bacilli	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158433_k127_1298453_4	745277.GRAQ_00133	5.057e-48	193.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,3FF6D@34037|Rahnella	1236|Gammaproteobacteria	E	GMC oxidoreductase	-	-	1.1.5.9	ko:K19813	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R00305	RC00066	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
SRR25158433_k127_1298453_3	671143.DAMO_0021	1.466e-50	193.0	COG3055@1|root,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria	2|Bacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
SRR25158433_k127_1298453_5	557599.MKAN_12095	1.068e-39	169.0	COG0515@1|root,COG3055@1|root,COG0515@2|Bacteria,COG3055@2|Bacteria,2I4I0@201174|Actinobacteria,23F8F@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	PFAM Protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Pkinase
SRR25158433_k127_1298453_2	1283299.AUKG01000001_gene1912	5.158e-69	256.0	COG1215@1|root,COG1215@2|Bacteria,2HQCH@201174|Actinobacteria,4CRWY@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_1298453_6	1267534.KB906755_gene4120	7.831e-33	142.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	GtrA,YdjC
SRR25158433_k127_1298453_1	667632.KB890220_gene2804	3.002e-83	287.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	galnAc-T11	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158433_k127_1298453_0	1380390.JIAT01000009_gene1930	3.587e-140	456.0	COG0438@1|root,COG0438@2|Bacteria,2GJI0@201174|Actinobacteria,4CQWI@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158433_k127_130975_4	1380390.JIAT01000009_gene513	1.758e-39	153.0	COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2HQCW@201174|Actinobacteria,4CRXA@84995|Rubrobacteria	84995|Rubrobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158433_k127_130975_1	469383.Cwoe_2429	4.746e-151	497.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4CQ9I@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158433_k127_130975_0	656024.FsymDg_3800	4.25e-313	971.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4ERWG@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158433_k127_130975_3	1122939.ATUD01000015_gene1002	2.733e-56	207.0	COG1226@1|root,COG1226@2|Bacteria,2HPDW@201174|Actinobacteria,4CQRY@84995|Rubrobacteria	84995|Rubrobacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
SRR25158433_k127_130975_5	929712.KI912613_gene28	7.266e-33	132.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4CTAW@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158433_k127_130975_2	469383.Cwoe_5433	1.324e-97	327.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4CSB4@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158433_k127_1316698_21	935840.JAEQ01000007_gene3973	9.839e-06	48.0	COG0582@1|root,COG0582@2|Bacteria,1RBMJ@1224|Proteobacteria,2U0ET@28211|Alphaproteobacteria,43N1U@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158433_k127_1316698_18	269799.Gmet_1207	7.673e-13	76.0	2DUF0@1|root,33QC9@2|Bacteria,1NU5F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1316698_14	469383.Cwoe_3080	1.294e-79	274.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CQ7R@84995|Rubrobacteria	84995|Rubrobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158433_k127_1316698_9	469383.Cwoe_3081	4.568e-92	313.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CPFG@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158433_k127_1316698_1	1122939.ATUD01000005_gene2648	9.521e-164	532.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CPSV@84995|Rubrobacteria	84995|Rubrobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158433_k127_1316698_4	469383.Cwoe_3083	4.556e-126	414.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4CQX8@84995|Rubrobacteria	84995|Rubrobacteria	S	Thiamin pyrophosphokinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR25158433_k127_1316698_16	643648.Slip_0444	5.388e-22	106.0	28JWD@1|root,2Z9M5@2|Bacteria,1UZF1@1239|Firmicutes,24HZN@186801|Clostridia,42K5F@68298|Syntrophomonadaceae	186801|Clostridia	S	Copper transport outer membrane protein, MctB	-	-	-	-	-	-	-	-	-	-	-	-	MctB
SRR25158433_k127_1316698_12	469383.Cwoe_3085	8.323e-82	282.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4CTZJ@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1316698_0	469383.Cwoe_3086	3.014e-252	799.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CPN2@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158433_k127_1316698_7	469383.Cwoe_3087	1.339e-100	346.0	COG2195@1|root,COG2195@2|Bacteria,2HPTW@201174|Actinobacteria,4CR7V@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158433_k127_1316698_8	469383.Cwoe_3088	1.836e-98	332.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria,4CTCT@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158433_k127_1316698_5	1283299.AUKG01000002_gene5299	1.185e-122	405.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CQMQ@84995|Rubrobacteria	84995|Rubrobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158433_k127_1316698_13	1380390.JIAT01000003_gene5461	8.105e-80	276.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CPMX@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158433_k127_1316698_11	1380390.JIAT01000003_gene5463	4.035e-85	293.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CQNS@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158433_k127_1316698_3	469383.Cwoe_3105	2.055e-130	424.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CPM8@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158433_k127_1316698_2	469383.Cwoe_3106	2.059e-131	441.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CPNK@84995|Rubrobacteria	84995|Rubrobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158433_k127_1316698_6	469383.Cwoe_3114	1.26e-108	364.0	COG1819@1|root,COG1819@2|Bacteria,2I8EN@201174|Actinobacteria,4CPRE@84995|Rubrobacteria	84995|Rubrobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158433_k127_1316698_10	1122939.ATUD01000005_gene2678	1.9e-91	312.0	COG4221@1|root,COG4221@2|Bacteria,2I5BD@201174|Actinobacteria,4CPN3@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_1316698_15	1380390.JIAT01000007_gene5183	2.258e-59	223.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria,4CRC2@84995|Rubrobacteria	84995|Rubrobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1316698_20	335541.Swol_1009	7.485e-07	55.0	COG1598@1|root,COG1598@2|Bacteria,1VJYE@1239|Firmicutes,24QYS@186801|Clostridia	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158433_k127_1316698_19	266117.Rxyl_0587	8.538e-10	62.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
SRR25158433_k127_1316698_17	443255.SCLAV_p1533	2.741e-18	86.0	COG2963@1|root,COG2963@2|Bacteria,2IQ8F@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158433_k127_1332858_1	1380390.JIAT01000014_gene6062	3.238e-43	162.0	COG0517@1|root,COG0517@2|Bacteria,2I6I8@201174|Actinobacteria,4CQHZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158433_k127_1332858_4	1380390.JIAT01000014_gene6069	2.378e-17	91.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria,2HSN9@201174|Actinobacteria,4CS57@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C
SRR25158433_k127_1332858_0	469383.Cwoe_5475	3.369e-76	267.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4CRU2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158433_k127_1332858_2	469383.Cwoe_1901	1.357e-21	102.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158433_k127_1336879_13	469383.Cwoe_3186	2.588e-65	229.0	COG0608@1|root,COG0608@2|Bacteria,2IK2U@201174|Actinobacteria,4CPI9@84995|Rubrobacteria	84995|Rubrobacteria	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158433_k127_1336879_3	469383.Cwoe_5342	2.062e-116	411.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1336879_19	1283299.AUKG01000001_gene3551	2.501e-37	164.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158433_k127_1336879_25	1121448.DGI_0529	8.865e-16	93.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria,2MF83@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158433_k127_1336879_22	1283299.AUKG01000002_gene5234	2.013e-17	95.0	2AUQD@1|root,31KDC@2|Bacteria,2HP8X@201174|Actinobacteria,4CQM7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1336879_0	1380390.JIAT01000010_gene4890	6.595e-261	835.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158433_k127_1336879_12	469383.Cwoe_3182	7.482e-68	240.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158433_k127_1336879_1	469383.Cwoe_3181	5.446e-146	471.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CP8G@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158433_k127_1336879_15	1380390.JIAT01000010_gene4896	3.303e-55	211.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CQA9@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158433_k127_1336879_18	1122939.ATUD01000005_gene2683	1.097e-48	180.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CQCR@84995|Rubrobacteria	84995|Rubrobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158433_k127_1336879_5	1380390.JIAT01000010_gene4902	1.171e-98	329.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CPAM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158433_k127_1336879_24	1283299.AUKG01000002_gene3646	4.296e-16	83.0	2BFTB@1|root,329N8@2|Bacteria,2HPDP@201174|Actinobacteria,4CQRK@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1336879_4	316274.Haur_3114	2.326e-116	386.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,376Y0@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158433_k127_1336879_14	469383.Cwoe_3161	1.674e-61	221.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CQEG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158433_k127_1336879_2	469383.Cwoe_3160	2.111e-134	437.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CPM6@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158433_k127_1336879_6	469383.Cwoe_3158	4.697e-95	333.0	COG1737@1|root,COG1737@2|Bacteria,2HGPB@201174|Actinobacteria,4CPA9@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158433_k127_1336879_26	67373.JOBF01000022_gene6588	2.155e-07	61.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1336879_27	106370.Francci3_0762	4.434e-07	62.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158433_k127_1336879_11	1122939.ATUD01000011_gene2240	1.735e-68	252.0	COG4325@1|root,COG4325@2|Bacteria,2GM70@201174|Actinobacteria,4CSZ9@84995|Rubrobacteria	84995|Rubrobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1336879_16	246197.MXAN_2547	3.701e-54	194.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2YUYA@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158433_k127_1336879_7	1380390.JIAT01000014_gene6050	7.082e-94	327.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRJD@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158433_k127_1336879_20	469383.Cwoe_4699	5.805e-34	134.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4CQ0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158433_k127_1336879_9	1380390.JIAT01000017_gene5272	5.705e-80	283.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CU6W@84995|Rubrobacteria	84995|Rubrobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
SRR25158433_k127_1336879_10	42256.RradSPS_1832	1.627e-71	248.0	COG0384@1|root,COG0384@2|Bacteria,2GMX1@201174|Actinobacteria,4CQWF@84995|Rubrobacteria	84995|Rubrobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158433_k127_1336879_23	1245469.S58_38650	2.812e-17	97.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria,2U1BI@28211|Alphaproteobacteria,3JVY2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
SRR25158433_k127_1336879_8	526225.Gobs_2142	7.052e-84	299.0	COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1336879_17	469383.Cwoe_0425	3.036e-50	199.0	COG2815@1|root,COG3291@1|root,COG2815@2|Bacteria,COG3291@2|Bacteria,2I9UB@201174|Actinobacteria,4CTSN@84995|Rubrobacteria	84995|Rubrobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158433_k127_1345772_12	521011.Mpal_1345	3.056e-16	94.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158433_k127_1345772_8	1283299.AUKG01000001_gene3551	1.395e-42	181.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158433_k127_1345772_0	1283299.AUKG01000001_gene1590	1.032e-140	482.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1345772_9	1121413.JMKT01000009_gene2170	6.662e-33	130.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158433_k127_1345772_2	1283299.AUKG01000002_gene3667	1.898e-115	395.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4CQPE@84995|Rubrobacteria	84995|Rubrobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
SRR25158433_k127_1345772_4	1380390.JIAT01000010_gene4762	2.223e-74	272.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158433_k127_1345772_5	1380390.JIAT01000010_gene4761	9.299e-59	223.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158433_k127_1345772_3	929712.KI912613_gene2740	5.678e-115	388.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158433_k127_1345772_7	1125863.JAFN01000001_gene1604	2.221e-50	201.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158433_k127_1345772_11	929712.KI912613_gene4676	1.333e-21	99.0	2A00B@1|root,30N2D@2|Bacteria,2HP1D@201174|Actinobacteria,4CQBW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1345772_1	1380390.JIAT01000014_gene6070	1.078e-128	430.0	COG0438@1|root,COG0438@2|Bacteria,2H432@201174|Actinobacteria,4CR80@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158433_k127_1345772_6	469383.Cwoe_1903	3.521e-57	208.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2GNXA@201174|Actinobacteria	201174|Actinobacteria	C	I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158433_k127_1369521_2	198628.Dda3937_04179	2.326e-06	51.0	2CAPJ@1|root,2Z90A@2|Bacteria,1P1EA@1224|Proteobacteria,1SB5U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1369521_1	91604.ID47_01005	4.86e-15	88.0	2C7AS@1|root,32RIS@2|Bacteria,1PB2Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1369521_0	1297742.A176_04207	1.717e-304	1045.0	COG1388@1|root,COG1388@2|Bacteria,1QXW7@1224|Proteobacteria,4341E@68525|delta/epsilon subdivisions,2X4MN@28221|Deltaproteobacteria,2YZ9B@29|Myxococcales	28221|Deltaproteobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158433_k127_1371665_2	469383.Cwoe_3176	8.625e-95	316.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CPZJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158433_k127_1371665_7	1449976.KALB_1592	3.141e-15	78.0	COG2002@1|root,COG2002@2|Bacteria,2GWND@201174|Actinobacteria,4ECX9@85010|Pseudonocardiales	201174|Actinobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158433_k127_1371665_6	994479.GL877878_gene2801	1.014e-43	162.0	COG1487@1|root,COG1487@2|Bacteria,2INNM@201174|Actinobacteria,4E5Z3@85010|Pseudonocardiales	201174|Actinobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_1371665_5	1122939.ATUD01000003_gene3544	2.684e-47	180.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CQI8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158433_k127_1371665_1	1122939.ATUD01000005_gene2702	3.171e-95	323.0	COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria,4CRBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158433_k127_1371665_3	1380390.JIAT01000010_gene4858	2.756e-77	262.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4CQBB@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158433_k127_1371665_0	469383.Cwoe_3200	8.64e-137	451.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CPT1@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158433_k127_1371665_4	469383.Cwoe_3201	1.254e-49	182.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CPDG@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158433_k127_137931_1	926550.CLDAP_16140	2.464e-76	268.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
SRR25158433_k127_137931_6	382464.ABSI01000012_gene2044	5.893e-39	160.0	COG4763@1|root,COG4763@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
SRR25158433_k127_137931_2	1120960.ATXG01000013_gene3467	7.083e-70	246.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4FKX7@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158433_k127_137931_3	926550.CLDAP_22690	1.008e-61	235.0	COG1215@1|root,COG2148@1|root,COG1215@2|Bacteria,COG2148@2|Bacteria,2G866@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Glycos_transf_2
SRR25158433_k127_137931_5	469383.Cwoe_5297	7.746e-45	185.0	COG3307@1|root,COG3307@2|Bacteria,2HREZ@201174|Actinobacteria,4CTDF@84995|Rubrobacteria	84995|Rubrobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158433_k127_137931_7	1380390.JIAT01000016_gene5568	1.27e-38	159.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CRKI@84995|Rubrobacteria	84995|Rubrobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158433_k127_137931_4	469383.Cwoe_0298	4.024e-48	174.0	COG0662@1|root,COG0662@2|Bacteria,2GXUC@201174|Actinobacteria,4CT1G@84995|Rubrobacteria	84995|Rubrobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer
SRR25158433_k127_137931_8	1157637.KB892102_gene1564	1.286e-31	128.0	COG1487@1|root,COG1487@2|Bacteria,2IJUM@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_137931_9	1961.JOAK01000039_gene4357	3.943e-07	54.0	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158433_k127_137931_0	1380390.JIAT01000009_gene2051	1.27e-231	736.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4CPU9@84995|Rubrobacteria	84995|Rubrobacteria	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158433_k127_1389518_5	1121952.ATXT01000013_gene2397	3.624e-48	176.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4FK7I@85023|Microbacteriaceae	201174|Actinobacteria	E	TOBE domain	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158433_k127_1389518_1	1380390.JIAT01000011_gene2579	6.179e-217	681.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4CPUF@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158433_k127_1389518_3	1283299.AUKG01000001_gene2621	3.551e-164	531.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria,4CRKT@84995|Rubrobacteria	84995|Rubrobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRR25158433_k127_1389518_2	469383.Cwoe_1334	1.2e-174	556.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4CRZC@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158433_k127_1389518_0	469383.Cwoe_1552	1.075e-227	713.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPEC@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158433_k127_1389518_6	1446473.JHWH01000007_gene389	1.531e-34	151.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2PV2I@265|Paracoccus	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158433_k127_1389518_9	439235.Dalk_0950	0.0001291	46.0	COG3360@1|root,COG3360@2|Bacteria,1Q2I5@1224|Proteobacteria,42VRR@68525|delta/epsilon subdivisions,2WRD2@28221|Deltaproteobacteria,2MM5C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158433_k127_1389518_4	1411123.JQNH01000001_gene2614	5.536e-89	308.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2U1TN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein related to capsule biosynthesis enzymes	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
SRR25158433_k127_1389518_8	1041159.AZUW01000046_gene3644	1.451e-05	55.0	COG1396@1|root,COG1396@2|Bacteria,1NGFD@1224|Proteobacteria,2V599@28211|Alphaproteobacteria,4BK2E@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1389518_7	1122939.ATUD01000009_gene3122	3.502e-22	106.0	COG0607@1|root,COG0607@2|Bacteria,2HFZ6@201174|Actinobacteria,4CQP4@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158433_k127_1395317_26	1122939.ATUD01000017_gene4042	5.819e-58	207.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
SRR25158433_k127_1395317_11	1283299.AUKG01000002_gene3856	1.784e-132	429.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CPAU@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158433_k127_1395317_10	469383.Cwoe_4640	1.669e-133	430.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CPQ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158433_k127_1395317_24	1380390.JIAT01000009_gene377	5.554e-65	225.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4CQ6D@84995|Rubrobacteria	84995|Rubrobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158433_k127_1395317_0	469383.Cwoe_0843	2.081e-255	796.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158433_k127_1395317_22	469383.Cwoe_4644	6.154e-76	263.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CRTI@84995|Rubrobacteria	84995|Rubrobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158433_k127_1395317_5	469383.Cwoe_4643	4.572e-170	546.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPNX@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158433_k127_1395317_12	469383.Cwoe_4642	1.309e-126	421.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CPVK@84995|Rubrobacteria	84995|Rubrobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158433_k127_1395317_34	1379270.AUXF01000002_gene1393	2.43e-27	121.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SRR25158433_k127_1395317_43	593105.S7A_07195	7.783e-06	52.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RCYA@1224|Proteobacteria,1S3GS@1236|Gammaproteobacteria,3W2WI@53335|Pantoea	1236|Gammaproteobacteria	K	transcriptional	IV02_05560	-	-	ko:K14056	-	-	-	-	ko00000,ko03000	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158433_k127_1395317_28	215803.DB30_3483	2.547e-47	178.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,42UJU@68525|delta/epsilon subdivisions,2WQI6@28221|Deltaproteobacteria,2YYTJ@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158433_k127_1395317_29	929712.KI912613_gene2771	9.116e-45	178.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4CQGV@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158433_k127_1395317_1	1232410.KI421421_gene3873	1.587e-197	625.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,43SUW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158433_k127_1395317_2	469383.Cwoe_0232	3.478e-186	590.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4CPRK@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1395317_42	1283299.AUKG01000001_gene3474	1.397e-06	56.0	COG3861@1|root,COG3861@2|Bacteria,2IKWD@201174|Actinobacteria	201174|Actinobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158433_k127_1395317_8	1283299.AUKG01000002_gene3829	2.517e-145	466.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CQB3@84995|Rubrobacteria	84995|Rubrobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158433_k127_1395317_20	1283299.AUKG01000002_gene3826	3.801e-77	265.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CR4C@84995|Rubrobacteria	84995|Rubrobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158433_k127_1395317_38	1123389.ATXJ01000032_gene1672	4.646e-14	80.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158433_k127_1395317_41	264732.Moth_2206	1.335e-06	53.0	COG4118@1|root,COG4118@2|Bacteria,1VAKT@1239|Firmicutes,24PQQ@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158433_k127_1395317_39	706587.Desti_0590	1.045e-12	72.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,42X7S@68525|delta/epsilon subdivisions,2WSVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158433_k127_1395317_4	469383.Cwoe_4652	1.35e-171	570.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CQI2@84995|Rubrobacteria	84995|Rubrobacteria	G	Starch synthase catalytic domain	-	-	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158433_k127_1395317_18	469383.Cwoe_4653	1.188e-99	343.0	COG1543@1|root,COG1543@2|Bacteria,2GKTI@201174|Actinobacteria,4CRV4@84995|Rubrobacteria	84995|Rubrobacteria	G	Domain of unknown function (DUF1957)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1957,Glyco_hydro_57
SRR25158433_k127_1395317_16	469383.Cwoe_4654	8.892e-119	412.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4CP67@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158433_k127_1395317_17	469383.Cwoe_4655	5.694e-109	370.0	COG0500@1|root,COG2226@2|Bacteria,2HPV9@201174|Actinobacteria,4CR9D@84995|Rubrobacteria	84995|Rubrobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158433_k127_1395317_31	1380390.JIAT01000009_gene2125	1.187e-40	163.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158433_k127_1395317_19	469383.Cwoe_4672	5.375e-98	332.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4CT2V@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylate cyclase regulatory domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRR25158433_k127_1395317_6	469383.Cwoe_4666	1.257e-159	517.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CPY9@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158433_k127_1395317_9	1380390.JIAT01000009_gene415	3.163e-145	475.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CRHI@84995|Rubrobacteria	84995|Rubrobacteria	D	Tubulin/FtsZ family, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsZ_C,Tubulin
SRR25158433_k127_1395317_15	1380390.JIAT01000009_gene416	8.183e-123	405.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CPVA@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158433_k127_1395317_21	469383.Cwoe_4669	3.053e-76	267.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4CPXW@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158433_k127_1395317_14	469383.Cwoe_4670	1.158e-124	424.0	COG0003@1|root,COG0003@2|Bacteria,2HG29@201174|Actinobacteria,4CTSC@84995|Rubrobacteria	84995|Rubrobacteria	D	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158433_k127_1395317_45	443254.Marpi_0294	0.0005551	51.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	spoIIAA	-	-	ko:K04749,ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko03021	-	-	-	STAS,STAS_2
SRR25158433_k127_1395317_30	1380390.JIAT01000009_gene421	1.072e-40	170.0	2ATZV@1|root,31JJQ@2|Bacteria,2HNRB@201174|Actinobacteria,4CPYQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1395317_27	469383.Cwoe_4680	5.21e-48	175.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria,4CQEM@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158433_k127_1395317_40	1380390.JIAT01000017_gene5277	2.063e-07	63.0	2B0FJ@1|root,31ST2@2|Bacteria,2HQ6F@201174|Actinobacteria,4CRPF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1395317_33	1380390.JIAT01000017_gene5278	1.112e-30	133.0	2AVF2@1|root,31M71@2|Bacteria,2HPWF@201174|Actinobacteria,4CRB2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM
SRR25158433_k127_1395317_32	1380390.JIAT01000017_gene5279	2.257e-32	135.0	COG3166@1|root,COG3166@2|Bacteria,2HPHC@201174|Actinobacteria,4CQVM@84995|Rubrobacteria	84995|Rubrobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1395317_23	1380390.JIAT01000017_gene5280	1.393e-65	238.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria,4CQH2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158433_k127_1395317_25	1283299.AUKG01000004_gene948	6.023e-65	230.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4CQAS@84995|Rubrobacteria	84995|Rubrobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158433_k127_1395317_37	929712.KI912613_gene3438	2.371e-15	82.0	COG2165@1|root,COG2165@2|Bacteria,2GTN8@201174|Actinobacteria,4CQSF@84995|Rubrobacteria	84995|Rubrobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158433_k127_1395317_13	1380390.JIAT01000017_gene5296	8.598e-125	411.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158433_k127_1395317_7	1380390.JIAT01000017_gene5297	8.13e-151	486.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158433_k127_1395317_3	1283299.AUKG01000004_gene967	5.831e-175	560.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4CPMS@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158433_k127_1396285_1	1283299.AUKG01000001_gene1591	4.78e-30	132.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158433_k127_1396285_0	1283299.AUKG01000001_gene1590	8.488e-133	467.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1399739_0	253839.SSNG_07466	0.0	2077.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_1401094_2	1435356.Y013_04845	1.156e-122	399.0	28KP8@1|root,2ZA7D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1401094_0	405948.SACE_3326	2.729e-243	773.0	COG0021@1|root,COG0021@2|Bacteria,2I36F@201174|Actinobacteria,4DZ6K@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the transketolase family	tkt3	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158433_k127_1401094_1	469383.Cwoe_4593	3.747e-148	477.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4CP6W@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158433_k127_1401094_3	469383.Cwoe_1111	3.186e-102	350.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4CPDC@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158433_k127_1401094_5	929712.KI912613_gene292	5.864e-09	62.0	COG3794@1|root,COG3794@2|Bacteria,2HR22@201174|Actinobacteria,4CSWU@84995|Rubrobacteria	84995|Rubrobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158433_k127_1401094_4	469383.Cwoe_4594	1.158e-23	102.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4CU2Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158433_k127_1406805_14	1283299.AUKG01000004_gene1223	1.301e-63	233.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158433_k127_1406805_20	1380390.JIAT01000016_gene5634	3.484e-44	168.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CP6R@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158433_k127_1406805_9	469383.Cwoe_2842	2.657e-107	359.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CP6H@84995|Rubrobacteria	84995|Rubrobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158433_k127_1406805_22	929712.KI912613_gene4398	1.875e-36	143.0	COG2030@1|root,COG2030@2|Bacteria,2HR1S@201174|Actinobacteria,4CSW6@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158433_k127_1406805_19	1283299.AUKG01000004_gene1228	1.377e-46	172.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4CSAG@84995|Rubrobacteria	84995|Rubrobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158433_k127_1406805_1	1380390.JIAT01000016_gene5643	1.74e-277	864.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CP62@84995|Rubrobacteria	84995|Rubrobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158433_k127_1406805_12	497964.CfE428DRAFT_4742	3.555e-83	283.0	COG3177@1|root,COG3177@2|Bacteria,46SEX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
SRR25158433_k127_1406805_4	469383.Cwoe_2836	5.314e-157	511.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CQCB@84995|Rubrobacteria	84995|Rubrobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158433_k127_1406805_25	1380390.JIAT01000016_gene5646	1.546e-28	116.0	COG0268@1|root,COG0268@2|Bacteria,2HRKP@201174|Actinobacteria,4CTNG@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S20	-	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158433_k127_1406805_17	469383.Cwoe_2834	3.618e-57	211.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158433_k127_1406805_8	1380390.JIAT01000016_gene5648	7.913e-116	399.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4CPP2@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158433_k127_1406805_21	1380390.JIAT01000016_gene5649	3.924e-44	168.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4CQW7@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158433_k127_1406805_30	573064.Mefer_1505	1.382e-06	56.0	COG0662@1|root,arCOG03003@2157|Archaea	2157|Archaea	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_1406805_0	469383.Cwoe_2829	0.0	1164.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158433_k127_1406805_23	1267533.KB906740_gene137	3.067e-33	138.0	29Y1S@1|root,30JUQ@2|Bacteria,3Y90C@57723|Acidobacteria,2JNWN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1406805_29	469383.Cwoe_3654	1.63e-09	66.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HTH_20,HTH_5
SRR25158433_k127_1406805_16	1380390.JIAT01000009_gene1986	1.469e-58	211.0	2AV6D@1|root,31KWR@2|Bacteria,2HPMX@201174|Actinobacteria,4CR03@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158433_k127_1406805_28	1283299.AUKG01000005_gene41	2.013e-24	111.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CQDN@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158433_k127_1406805_18	1380390.JIAT01000002_gene6019	7.921e-53	193.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CQ75@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158433_k127_1406805_6	469383.Cwoe_2672	1.759e-143	469.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CPDP@84995|Rubrobacteria	84995|Rubrobacteria	E	Aldehyde dehydrogenase family	-	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158433_k127_1406805_7	469383.Cwoe_2670	4.767e-135	442.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CR1D@84995|Rubrobacteria	84995|Rubrobacteria	E	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158433_k127_1406805_13	1293054.HSACCH_00771	8.587e-68	245.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,24BFR@186801|Clostridia	186801|Clostridia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158433_k127_1406805_5	469383.Cwoe_2668	4.63e-144	471.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CPMW@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158433_k127_1406805_24	469383.Cwoe_2665	2.699e-30	122.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CQPP@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158433_k127_1406805_27	469383.Cwoe_2664	1.744e-26	115.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4CQJ4@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158433_k127_1406805_2	469383.Cwoe_2663	9.079e-233	733.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CPSJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158433_k127_1406805_10	469383.Cwoe_2662	9.18e-107	382.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CPV0@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158433_k127_1406805_3	469383.Cwoe_2661	2.472e-159	522.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CPBN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158433_k127_1406805_15	469383.Cwoe_2659	5.026e-60	217.0	COG1792@1|root,COG1792@2|Bacteria	2|Bacteria	M	regulation of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158433_k127_1406805_11	1283299.AUKG01000005_gene64	5.85e-96	318.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158433_k127_1502869_1	1380390.JIAT01000011_gene2876	8.353e-111	368.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4CSMA@84995|Rubrobacteria	84995|Rubrobacteria	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158433_k127_1502869_3	1122939.ATUD01000016_gene1821	4.534e-64	241.0	COG2723@1|root,COG2723@2|Bacteria,2HFEG@201174|Actinobacteria,4CRFZ@84995|Rubrobacteria	2|Bacteria	G	6-phospho-beta-galactosidase activity	-	-	-	ko:K21000	ko02025,map02025	-	-	-	ko00000,ko00001	-	GH39	-	Cellulase
SRR25158433_k127_1502869_2	1122939.ATUD01000016_gene1819	1.577e-86	310.0	COG3307@1|root,COG3307@2|Bacteria,2HREZ@201174|Actinobacteria,4CTDF@84995|Rubrobacteria	84995|Rubrobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158433_k127_1502869_4	710685.MycrhN_5461	0.0001089	49.0	2AZ4X@1|root,31RBH@2|Bacteria,2ITDG@201174|Actinobacteria,23B1F@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4333
SRR25158433_k127_1502869_0	469383.Cwoe_4211	1.391e-140	449.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158433_k127_1509577_18	469383.Cwoe_1908	8.129e-107	354.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4CS5J@84995|Rubrobacteria	84995|Rubrobacteria	O	UbiA prenyltransferase family	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158433_k127_1509577_16	929712.KI912613_gene4668	3.778e-111	388.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CP91@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158433_k127_1509577_50	469383.Cwoe_1910	2.448e-32	134.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4CPBE@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C oxidase subunit II, transmembrane domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158433_k127_1509577_20	1380390.JIAT01000014_gene6049	5.619e-91	310.0	COG0671@1|root,COG0671@2|Bacteria,2HPYC@201174|Actinobacteria,4CRDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158433_k127_1509577_28	1380390.JIAT01000014_gene6048	5.713e-80	282.0	COG0392@1|root,COG0392@2|Bacteria,2HQ3T@201174|Actinobacteria,4CRKA@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158433_k127_1509577_10	469383.Cwoe_1914	8.995e-134	434.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CP86@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158433_k127_1509577_38	485915.Dret_1540	4.797e-51	196.0	28MZW@1|root,2ZB6I@2|Bacteria,1RCF3@1224|Proteobacteria,42PN4@68525|delta/epsilon subdivisions,2WMHF@28221|Deltaproteobacteria,2MBJ4@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_32	485915.Dret_1539	2.739e-70	261.0	28JZ8@1|root,2Z9PB@2|Bacteria,1R6WD@1224|Proteobacteria,42PD4@68525|delta/epsilon subdivisions,2WJTW@28221|Deltaproteobacteria,2MBEK@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_4	1158760.AQXP01000051_gene699	3.35e-202	667.0	COG0553@1|root,COG0553@2|Bacteria,1MX26@1224|Proteobacteria,1RZZU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
SRR25158433_k127_1509577_43	1380390.JIAT01000010_gene3610	5.054e-42	160.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CRAQ@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158433_k127_1509577_48	1193181.BN10_30006	1.82e-33	130.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4FEZS@85021|Intrasporangiaceae	201174|Actinobacteria	P	sodium proton antiporter	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,zf-UBP
SRR25158433_k127_1509577_60	935866.JAER01000035_gene3235	1.899e-14	75.0	COG1525@1|root,COG2333@1|root,COG1525@2|Bacteria,COG2333@2|Bacteria,2HNFC@201174|Actinobacteria,4DVET@85009|Propionibacteriales	201174|Actinobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
SRR25158433_k127_1509577_0	469383.Cwoe_1129	9.341e-272	862.0	COG2015@1|root,COG2015@2|Bacteria,2GK38@201174|Actinobacteria	201174|Actinobacteria	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
SRR25158433_k127_1509577_21	469383.Cwoe_2190	1.363e-89	309.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158433_k127_1509577_46	1380390.JIAT01000010_gene4399	4.276e-34	146.0	COG3837@1|root,COG3837@2|Bacteria,2HR0G@201174|Actinobacteria,4CSU9@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_1509577_24	469383.Cwoe_2162	7.574e-84	285.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4CS43@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158433_k127_1509577_11	68223.JNZY01000007_gene3158	3.431e-131	436.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1509577_35	1380390.JIAT01000009_gene1846	5.859e-65	231.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4CS41@84995|Rubrobacteria	84995|Rubrobacteria	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
SRR25158433_k127_1509577_8	644966.Tmar_2129	7.317e-156	501.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158433_k127_1509577_55	469383.Cwoe_1917	8.763e-24	118.0	COG0702@1|root,COG0702@2|Bacteria,2HQUJ@201174|Actinobacteria,4CSM6@84995|Rubrobacteria	84995|Rubrobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158433_k127_1509577_15	420324.KI911965_gene544	3.92e-118	382.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,1JUHK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	C-terminal domain of 1-Cys peroxiredoxin	MA20_35715	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158433_k127_1509577_41	1283299.AUKG01000001_gene3255	1.163e-45	170.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4CQAZ@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158433_k127_1509577_22	1380390.JIAT01000016_gene5642	8.863e-88	299.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQG8@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158433_k127_1509577_53	469383.Cwoe_1919	1.678e-29	126.0	COG1765@1|root,COG1765@2|Bacteria,2IIKU@201174|Actinobacteria,4CQ86@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158433_k127_1509577_44	1304865.JAGF01000001_gene3122	1.763e-41	159.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria	201174|Actinobacteria	S	adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158433_k127_1509577_9	1283299.AUKG01000001_gene3257	1.361e-137	452.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4CS23@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158433_k127_1509577_37	83332.Rv2829c	2.579e-54	194.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_1509577_58	83332.Rv2830c	1.024e-20	94.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040007,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0080090,GO:2000112	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158433_k127_1509577_63	1380390.JIAT01000009_gene967	3.9e-11	66.0	2B5N1@1|root,31YH9@2|Bacteria,2HR5Y@201174|Actinobacteria,4CT1J@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_25	882086.SacxiDRAFT_1982	2.312e-83	283.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4DX43@85010|Pseudonocardiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158433_k127_1509577_27	1283299.AUKG01000002_gene4971	1.151e-81	280.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria,4CQPG@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158433_k127_1509577_52	1229780.BN381_50050	2.294e-30	125.0	COG4683@1|root,COG4683@2|Bacteria,2IQAB@201174|Actinobacteria	201174|Actinobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
SRR25158433_k127_1509577_65	401053.AciPR4_2394	6.268e-09	62.0	COG1396@1|root,COG1396@2|Bacteria,3Y4VD@57723|Acidobacteria,2JJHN@204432|Acidobacteriia	204432|Acidobacteriia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
SRR25158433_k127_1509577_26	1463921.JODF01000005_gene6237	1.228e-82	286.0	28SI0@1|root,2ZEUB@2|Bacteria,2GNT0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR25158433_k127_1509577_47	1041142.ATTP01000018_gene6611	6.595e-34	137.0	COG0645@1|root,COG0645@2|Bacteria,1REQ8@1224|Proteobacteria,2U8V2@28211|Alphaproteobacteria,4BE0E@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Chloramphenicol phosphotransferase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
SRR25158433_k127_1509577_13	1380390.JIAT01000009_gene2073	1.497e-125	407.0	COG3000@1|root,COG3000@2|Bacteria,2GMF0@201174|Actinobacteria,4CRKH@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158433_k127_1509577_29	634497.HAH_0162	2.127e-73	257.0	COG0702@1|root,arCOG03015@2157|Archaea,2XT7V@28890|Euryarchaeota,23T9H@183963|Halobacteria	183963|Halobacteria	M	Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158433_k127_1509577_23	926560.KE387027_gene1021	3.598e-87	301.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_66	1496688.ER33_09040	8.038e-08	57.0	2EI68@1|root,33BXK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_69	1089544.KB912942_gene2650	4.824e-06	53.0	COG3462@1|root,COG3462@2|Bacteria,2GWIQ@201174|Actinobacteria,4E7IH@85010|Pseudonocardiales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158433_k127_1509577_59	1380390.JIAT01000009_gene862	2.873e-18	89.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria,4CTHC@84995|Rubrobacteria	84995|Rubrobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158433_k127_1509577_19	1380390.JIAT01000011_gene2324	6.71e-103	352.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4CTG0@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158433_k127_1509577_40	1121946.AUAX01000020_gene3143	6.59e-48	183.0	COG2220@1|root,COG2220@2|Bacteria,2GN98@201174|Actinobacteria,4DCC4@85008|Micromonosporales	201174|Actinobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158433_k127_1509577_1	469383.Cwoe_2964	3.347e-239	758.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRR25158433_k127_1509577_7	1380390.JIAT01000011_gene2320	2.199e-160	517.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4CR6A@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158433_k127_1509577_51	469383.Cwoe_0856	4.743e-31	126.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158433_k127_1509577_54	1179773.BN6_59010	1.976e-24	110.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4E5WF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_42	1120797.KB908282_gene3960	2.796e-45	166.0	COG4430@1|root,COG4430@2|Bacteria,2IQK3@201174|Actinobacteria,23AQD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158433_k127_1509577_33	1214242.B446_00790	1.047e-69	246.0	COG3485@1|root,COG3485@2|Bacteria,2GMAP@201174|Actinobacteria	201174|Actinobacteria	Q	dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158433_k127_1509577_14	298653.Franean1_3879	1.944e-118	385.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4EUQX@85013|Frankiales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158433_k127_1509577_17	469383.Cwoe_3638	1.032e-108	361.0	COG1254@1|root,COG1254@2|Bacteria,2IT6J@201174|Actinobacteria,4CTJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158433_k127_1509577_30	469383.Cwoe_0783	2.862e-73	264.0	COG3324@1|root,COG3324@2|Bacteria,2I6WX@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_34	1048339.KB913029_gene1795	5e-68	251.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4ERI4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	spk	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,Pkinase_Tyr
SRR25158433_k127_1509577_2	1079460.ATTQ01000010_gene140	9.635e-222	691.0	COG1052@1|root,COG1052@2|Bacteria,1PDP1@1224|Proteobacteria,2U0EU@28211|Alphaproteobacteria,4BBBN@82115|Rhizobiaceae	28211|Alphaproteobacteria	CH	Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms	fdh	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158433_k127_1509577_6	469383.Cwoe_3280	1.453e-186	589.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CPTW@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158433_k127_1509577_57	469383.Cwoe_1200	8.089e-21	99.0	2B7Q6@1|root,320W2@2|Bacteria,2HRM4@201174|Actinobacteria,4CTNY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_70	530564.Psta_4002	0.0006493	49.0	COG2193@1|root,COG2193@2|Bacteria,2IZYI@203682|Planctomycetes	203682|Planctomycetes	P	COG2193 Bacterioferritin (cytochrome b1)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158433_k127_1509577_68	1160718.SU9_11413	4.674e-06	53.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158433_k127_1509577_31	1501230.ET33_22305	2.66e-72	252.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,26Y28@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158433_k127_1509577_39	1380390.JIAT01000013_gene295	3.543e-48	185.0	COG3685@1|root,COG3685@2|Bacteria,2II1C@201174|Actinobacteria,4CSVV@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158433_k127_1509577_56	1283299.AUKG01000003_gene647	7.104e-22	109.0	COG2508@1|root,COG2508@2|Bacteria,2I7NK@201174|Actinobacteria,4CTHJ@84995|Rubrobacteria	84995|Rubrobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158433_k127_1509577_45	1206735.BAGG01000266_gene7074	9.563e-40	156.0	2EGUB@1|root,33AKH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1509577_5	469383.Cwoe_4157	4.339e-202	640.0	COG4799@1|root,COG4799@2|Bacteria,2I16G@201174|Actinobacteria,4CPR2@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158433_k127_1509577_12	66429.JOFL01000013_gene2903	5.915e-129	418.0	COG1409@1|root,COG1409@2|Bacteria,2GKMR@201174|Actinobacteria	201174|Actinobacteria	Q	metallophosphoesterase	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158433_k127_1509577_36	1223523.H340_30358	4.233e-63	228.0	COG2977@1|root,COG2977@2|Bacteria,2IIA2@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the P-Pant transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
SRR25158433_k127_1509577_3	1463861.JNXE01000068_gene2998	3.125e-213	679.0	COG3321@1|root,COG3321@2|Bacteria	2|Bacteria	Q	synthase	pks9	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_1514348_0	290397.Adeh_2624	3.483e-72	248.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158433_k127_1514348_3	1122939.ATUD01000011_gene2224	1.627e-45	171.0	COG3871@1|root,COG3871@2|Bacteria,2I2QZ@201174|Actinobacteria,4CQ6F@84995|Rubrobacteria	84995|Rubrobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158433_k127_1514348_1	1211815.CBYP010000045_gene800	4.881e-63	231.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,OpgC_C
SRR25158433_k127_1514348_5	472759.Nhal_2021	6.846e-13	74.0	2DPYJ@1|root,333YW@2|Bacteria,1NCVQ@1224|Proteobacteria,1SDCB@1236|Gammaproteobacteria,1X1KX@135613|Chromatiales	135613|Chromatiales	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158433_k127_1514348_4	395494.Galf_1613	4.947e-27	114.0	COG3744@1|root,COG3744@2|Bacteria,1RJXF@1224|Proteobacteria	1224|Proteobacteria	S	PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_1514348_6	1380347.JNII01000007_gene382	1.615e-11	76.0	COG2385@1|root,COG2385@2|Bacteria,2HEYF@201174|Actinobacteria,4ESKX@85013|Frankiales	201174|Actinobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
SRR25158433_k127_1514348_2	1476876.JOJO01000013_gene4545	1.555e-52	202.0	COG3409@1|root,COG3409@2|Bacteria,2I57M@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,PG_binding_1
SRR25158433_k127_1525284_0	1283299.AUKG01000001_gene2897	5.942e-207	649.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CRMB@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1525284_27	1380390.JIAT01000011_gene2813	1.492e-12	81.0	2BG9U@1|root,32A77@2|Bacteria,2HPFU@201174|Actinobacteria,4CQUB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1525284_29	1500890.JQNL01000001_gene1520	5.661e-06	52.0	28I2C@1|root,2Z86I@2|Bacteria,1PZZR@1224|Proteobacteria,1SM0S@1236|Gammaproteobacteria,1X64Z@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1525284_19	1283299.AUKG01000001_gene2946	7.188e-29	119.0	COG3654@1|root,COG3654@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158433_k127_1525284_24	479434.Sthe_2534	7.407e-16	92.0	COG2373@1|root,COG3420@1|root,COG2373@2|Bacteria,COG3420@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K13735,ko:K21449	ko05100,map05100	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	Big_1,DUF3494,IAT_beta,Invasin_D3
SRR25158433_k127_1525284_15	469383.Cwoe_1113	4.804e-64	222.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4CQMC@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158433_k127_1525284_14	266117.Rxyl_3053	2.778e-73	259.0	COG0530@1|root,COG0530@2|Bacteria,2IA02@201174|Actinobacteria	201174|Actinobacteria	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158433_k127_1525284_22	469383.Cwoe_1654	2.451e-20	103.0	2A05G@1|root,30N88@2|Bacteria,2HP1P@201174|Actinobacteria,4CQC6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1525284_12	1298863.AUEP01000006_gene3261	2.833e-100	339.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4DNUY@85009|Propionibacteriales	201174|Actinobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158433_k127_1525284_1	469383.Cwoe_1645	2.639e-189	601.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CPGF@84995|Rubrobacteria	84995|Rubrobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158433_k127_1525284_2	469383.Cwoe_1723	3.047e-177	583.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CRWU@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPase (P-type)	-	-	3.6.3.8	ko:K01537,ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.23	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158433_k127_1525284_11	1123258.AQXZ01000019_gene2911	9.607e-101	339.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4FWNJ@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158433_k127_1525284_10	118168.MC7420_5104	4.625e-103	355.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158433_k127_1525284_21	1137269.AZWL01000002_gene6540	1.628e-27	125.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria	201174|Actinobacteria	C	NADP transhydrogenase	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158433_k127_1525284_4	208444.JNYY01000007_gene7956	6.941e-168	539.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158433_k127_1525284_16	1283299.AUKG01000001_gene1940	6.619e-53	202.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158433_k127_1525284_8	28444.JODQ01000016_gene7074	1.835e-104	351.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4EFSE@85012|Streptosporangiales	201174|Actinobacteria	S	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
SRR25158433_k127_1525284_9	526225.Gobs_0202	2.961e-104	348.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4ERND@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR25158433_k127_1525284_17	1411123.JQNH01000001_gene2614	9.684e-53	202.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2U1TN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein related to capsule biosynthesis enzymes	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
SRR25158433_k127_1525284_13	1120936.KB907209_gene1393	4.534e-84	289.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4EGV0@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158433_k127_1525284_3	469383.Cwoe_4688	4.388e-174	550.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4CP7Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158433_k127_1525284_18	1411123.JQNH01000001_gene2614	6.561e-52	209.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2U1TN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein related to capsule biosynthesis enzymes	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
SRR25158433_k127_1525284_26	670487.Ocepr_1188	6.439e-13	77.0	COG2050@1|root,COG2050@2|Bacteria,1WJS6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158433_k127_1525284_6	391625.PPSIR1_41589	5.467e-130	421.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158433_k127_1525284_5	1283299.AUKG01000002_gene3742	2.492e-167	545.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CRJ5@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158433_k127_1525284_25	243164.DET1448	3.879e-15	78.0	29WVC@1|root,30IH0@2|Bacteria,2G9KW@200795|Chloroflexi,34DPM@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1525284_28	469383.Cwoe_3713	4.675e-06	49.0	COG4118@1|root,COG4118@2|Bacteria,2GZ1A@201174|Actinobacteria,4CTTN@84995|Rubrobacteria	84995|Rubrobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158433_k127_1525284_23	1223542.GM1_067_00020	1.377e-17	83.0	COG1487@1|root,COG1487@2|Bacteria,2IGMY@201174|Actinobacteria,4GG9G@85026|Gordoniaceae	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_1525284_7	1283299.AUKG01000001_gene1590	1.99e-120	413.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1551985_3	1048339.KB913029_gene2507	5.923e-160	519.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU9G@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_1551985_12	1380390.JIAT01000009_gene648	1.042e-23	104.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158433_k127_1551985_6	471852.Tcur_1612	1.44e-116	420.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4EGE8@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158433_k127_1551985_2	196162.Noca_0969	2.134e-197	643.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158433_k127_1551985_7	365528.KB891210_gene2136	2.438e-96	321.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158433_k127_1551985_0	1410634.JHVD01000027_gene1655	1.273e-298	940.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158433_k127_1551985_13	408672.NBCG_00751	5.004e-20	92.0	COG0778@1|root,COG0778@2|Bacteria,2I5BC@201174|Actinobacteria,4DSK6@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158433_k127_1551985_8	1415778.JQMM01000001_gene2144	9.493e-71	248.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1J61C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158433_k127_1551985_5	1298863.AUEP01000013_gene4093	1.408e-133	441.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4DT97@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1,YHS
SRR25158433_k127_1551985_4	378806.STAUR_2126	9.637e-136	456.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42U7Q@68525|delta/epsilon subdivisions,2X8TG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158433_k127_1551985_1	1108045.GORHZ_075_00140	1.491e-210	711.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4GA4F@85026|Gordoniaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158433_k127_1551985_11	469383.Cwoe_0942	4.438e-40	160.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	MA20_09295	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	Pkinase,Usp
SRR25158433_k127_1551985_9	1150864.MILUP08_45428	9.101e-67	243.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DCDB@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158433_k127_161399_15	1048834.TC41_1936	3.143e-53	199.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,278YD@186823|Alicyclobacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158433_k127_161399_3	1122939.ATUD01000015_gene1015	1.395e-140	460.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CPKE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158433_k127_161399_7	469383.Cwoe_5876	1.16e-99	331.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CSM2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158433_k127_161399_12	469383.Cwoe_5875	3.061e-59	222.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria,4CQ9M@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158433_k127_161399_11	1380390.JIAT01000009_gene1907	2.655e-65	230.0	COG1131@1|root,COG1131@2|Bacteria,2H5DY@201174|Actinobacteria,4CSCC@84995|Rubrobacteria	84995|Rubrobacteria	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158433_k127_161399_1	1283299.AUKG01000001_gene1885	2.52e-158	518.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158433_k127_161399_5	246194.CHY_2201	1.105e-125	441.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,42FF6@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158433_k127_161399_18	749927.AMED_2743	5.595e-28	123.0	COG0346@1|root,COG0346@2|Bacteria,2IKBZ@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158433_k127_161399_21	460265.Mnod_4680	1.046e-06	59.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,1JVIX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158433_k127_161399_9	1283299.AUKG01000001_gene1647	2.977e-85	291.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria,4CU4M@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158433_k127_161399_6	469383.Cwoe_3261	1.566e-116	386.0	COG1595@1|root,COG3631@1|root,COG1595@2|Bacteria,COG3631@2|Bacteria,2GMRK@201174|Actinobacteria,4CRRC@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158433_k127_161399_0	469383.Cwoe_0346	5.748e-195	619.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CPI3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_161399_4	1037409.BJ6T_56240	9.097e-138	451.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc,Hydrolase_4,Trans_reg_C
SRR25158433_k127_161399_10	1463841.JOIR01000012_gene2165	7.869e-68	236.0	2F8F6@1|root,340TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_161399_8	469383.Cwoe_1070	2.871e-96	324.0	KOG2524@1|root,2ZJ84@2|Bacteria	2|Bacteria	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
SRR25158433_k127_161399_17	1237500.ANBA01000008_gene492	4.396e-37	145.0	2AW22@1|root,31MWT@2|Bacteria,2IKWE@201174|Actinobacteria,4EJMY@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
SRR25158433_k127_161399_13	1273125.Rrhod_1513	3.53e-57	204.0	COG3427@1|root,COG3427@2|Bacteria,2I3CZ@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_161399_14	469383.Cwoe_3833	1.983e-55	205.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4CS2X@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158433_k127_161399_16	469383.Cwoe_3833	1.656e-52	190.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4CS2X@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158433_k127_161399_2	446462.Amir_4368	3.159e-143	463.0	COG1960@1|root,COG1960@2|Bacteria,2I5JQ@201174|Actinobacteria,4E1PG@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_161399_20	1380390.JIAT01000010_gene4647	8.707e-08	60.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_161399_22	1122939.ATUD01000016_gene1843	4.433e-06	51.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1663348_11	469383.Cwoe_2898	8.317e-17	85.0	COG1214@1|root,COG1214@2|Bacteria,2HP59@201174|Actinobacteria,4CQH7@84995|Rubrobacteria	84995|Rubrobacteria	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158433_k127_1663348_7	469383.Cwoe_2899	1.419e-56	202.0	COG0454@1|root,COG0456@2|Bacteria,2HPAC@201174|Actinobacteria,4CQNP@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158433_k127_1663348_5	266117.Rxyl_0812	1.175e-104	349.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CPNE@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158433_k127_1663348_10	1283299.AUKG01000004_gene1093	1.57e-17	85.0	COG0695@1|root,COG0695@2|Bacteria,2HRFR@201174|Actinobacteria,4CTEJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158433_k127_1663348_6	469383.Cwoe_2902	1.536e-98	326.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4CPVR@84995|Rubrobacteria	84995|Rubrobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,DUF836,Put_DNA-bind_N
SRR25158433_k127_1663348_2	469383.Cwoe_2903	1.493e-132	443.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158433_k127_1663348_0	469383.Cwoe_2905	2.943e-303	943.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158433_k127_1663348_9	1459636.NTE_02491	5.705e-21	98.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1663348_8	469383.Cwoe_1560	1.608e-46	182.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158433_k127_1663348_4	1380390.JIAT01000010_gene4553	1.093e-109	366.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4CPB1@84995|Rubrobacteria	84995|Rubrobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158433_k127_1663348_1	469383.Cwoe_2908	6.143e-215	684.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2GJ75@201174|Actinobacteria,4CPFI@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
SRR25158433_k127_1663348_3	469383.Cwoe_2910	1.544e-128	428.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2HF4S@201174|Actinobacteria,4CPSY@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
SRR25158433_k127_1664780_1	469383.Cwoe_2648	2.477e-58	203.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158433_k127_1664780_3	392499.Swit_3804	0.0004631	45.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,2UB7B@28211|Alphaproteobacteria,2K58B@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158433_k127_1664780_2	1328313.DS2_08318	2.202e-30	128.0	COG0454@1|root,COG0456@2|Bacteria,1RKY5@1224|Proteobacteria,1S6KM@1236|Gammaproteobacteria,467S7@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	VY92_01935	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158433_k127_1664780_0	471852.Tcur_1531	3.479e-130	421.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4EI0M@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158433_k127_1671066_11	179408.Osc7112_2223	2.573e-27	112.0	COG2048@1|root,COG2048@2|Bacteria,1G038@1117|Cyanobacteria,1H8FD@1150|Oscillatoriales	1117|Cyanobacteria	C	Heterodisulfide reductase subunit B	hdrB	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
SRR25158433_k127_1671066_2	469383.Cwoe_2622	2.072e-147	479.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CS0G@84995|Rubrobacteria	84995|Rubrobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SRR25158433_k127_1671066_9	469383.Cwoe_2623	2.261e-29	135.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	CBS,GGDEF,HisKA,SpoIIE
SRR25158433_k127_1671066_4	469383.Cwoe_5289	1.644e-127	437.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CQ0I@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158433_k127_1671066_3	471852.Tcur_4886	1.27e-133	439.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4EG8Z@85012|Streptosporangiales	201174|Actinobacteria	E	ACT domain	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158433_k127_1671066_10	1034943.BN1094_01600	3.92e-28	120.0	COG1695@1|root,COG1695@2|Bacteria,1NCF4@1224|Proteobacteria	1224|Proteobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158433_k127_1671066_1	585531.HMPREF0063_11548	1.286e-182	601.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DNJP@85009|Propionibacteriales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_1671066_6	1380390.JIAT01000009_gene1980	3.376e-60	218.0	COG0789@1|root,COG0789@2|Bacteria,2HSQA@201174|Actinobacteria,4CS71@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158433_k127_1671066_14	512565.AMIS_54740	5.313e-10	69.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,2H31X@201174|Actinobacteria,4DJAU@85008|Micromonosporales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158433_k127_1671066_5	1179773.BN6_07170	2.204e-83	291.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4E10C@85010|Pseudonocardiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4,Peptidase_S9
SRR25158433_k127_1671066_7	469383.Cwoe_3470	2.607e-55	214.0	COG1225@1|root,COG1225@2|Bacteria,2I5Q2@201174|Actinobacteria,4CT3H@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRR25158433_k127_1671066_13	1463900.JOIX01000062_gene1701	6.906e-15	82.0	COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	ypeA	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158433_k127_1671066_15	996637.SGM_1333	2.139e-05	53.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh_2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_1671066_0	1463841.JOIR01000011_gene2805	9.157e-218	685.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158433_k127_1671066_8	929712.KI912613_gene4994	1.735e-44	166.0	COG2867@1|root,COG2867@2|Bacteria,2HQ5J@201174|Actinobacteria,4CRNR@84995|Rubrobacteria	84995|Rubrobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158433_k127_1671066_12	469383.Cwoe_0896	2.281e-24	108.0	COG0739@1|root,COG3409@1|root,COG0739@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,PG_binding_1,Peptidase_M23
SRR25158433_k127_1695400_0	749414.SBI_00651	5.002e-296	934.0	COG0300@1|root,COG0604@1|root,COG1028@1|root,COG3321@1|root,COG0300@2|Bacteria,COG0604@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	ko:K12436,ko:K16386,ko:K19208	ko01052,map01052	-	-	-	ko00000,ko00001,ko01004	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158433_k127_1704015_11	1131813.AQVT01000001_gene3837	9.479e-17	88.0	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,2UFA4@28211|Alphaproteobacteria,1JUQM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158433_k127_1704015_7	1121468.AUBR01000025_gene2973	2.494e-44	172.0	COG1215@1|root,COG1215@2|Bacteria,1UK60@1239|Firmicutes,24IGY@186801|Clostridia,42J7I@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_1704015_8	317936.Nos7107_0193	6.187e-42	163.0	COG0500@1|root,COG0500@2|Bacteria,1G9SQ@1117|Cyanobacteria,1HR4H@1161|Nostocales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158433_k127_1704015_9	1380390.JIAT01000016_gene5568	9.691e-36	150.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CRKI@84995|Rubrobacteria	84995|Rubrobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158433_k127_1704015_12	314254.OA2633_13825	1.024e-11	75.0	2DYBZ@1|root,34935@2|Bacteria,1N33C@1224|Proteobacteria,2UC0C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158433_k127_1704015_10	610130.Closa_0549	5.901e-29	133.0	2DG69@1|root,32U6P@2|Bacteria,1VY6V@1239|Firmicutes,24PBX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1704015_2	1122185.N792_01595	1.828e-117	387.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,1RXAQ@1236|Gammaproteobacteria,1X73Q@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0110 Acetyltransferase (isoleucine patch superfamily)	wxcM	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep
SRR25158433_k127_1704015_4	35754.JNYJ01000001_gene7217	6.715e-93	330.0	COG0463@1|root,COG0463@2|Bacteria,2I3C0@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_1704015_3	1267534.KB906754_gene3500	5.472e-96	327.0	COG0399@1|root,COG0399@2|Bacteria,3Y2G1@57723|Acidobacteria,2JI3T@204432|Acidobacteriia	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	ntdA	GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.104	ko:K18653	-	-	R10698	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158433_k127_1704015_0	1283299.AUKG01000001_gene2039	2.16e-144	486.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CPTQ@84995|Rubrobacteria	84995|Rubrobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158433_k127_1704015_6	1117379.BABA_01700	2.22e-68	241.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,1ZBZD@1386|Bacillus	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158433_k127_1704015_1	469383.Cwoe_5789	1.038e-136	470.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CPRY@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158433_k127_1704015_5	469383.Cwoe_3157	9.308e-70	246.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria,4CQ10@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158433_k127_1711033_1	469383.Cwoe_3710	4.786e-140	452.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4CPE1@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_1711033_2	469383.Cwoe_3712	7.354e-105	370.0	COG2244@1|root,COG2244@2|Bacteria,2HRC7@201174|Actinobacteria,4CT9N@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
SRR25158433_k127_1711033_0	1380390.JIAT01000010_gene3523	2.66e-189	608.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4CRMU@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
SRR25158433_k127_1711033_3	1283299.AUKG01000001_gene1590	8.333e-10	64.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1723775_1	469383.Cwoe_1710	3.749e-153	524.0	COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,2HGJ9@201174|Actinobacteria,4CRYN@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_1723775_4	1283299.AUKG01000001_gene2856	1.343e-109	372.0	COG1463@1|root,COG1463@2|Bacteria,2IDGH@201174|Actinobacteria,4CREE@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158433_k127_1723775_6	1380390.JIAT01000011_gene2771	5.451e-89	315.0	COG1463@1|root,COG1463@2|Bacteria,2GMHC@201174|Actinobacteria,4CS82@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158433_k127_1723775_3	1380390.JIAT01000011_gene2772	1.313e-127	441.0	COG1463@1|root,COG1463@2|Bacteria,2HNKW@201174|Actinobacteria,4CPPQ@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158433_k127_1723775_5	1380390.JIAT01000011_gene2773	5.042e-106	362.0	COG1463@1|root,COG1463@2|Bacteria,2I8TQ@201174|Actinobacteria,4CRI0@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158433_k127_1723775_7	469383.Cwoe_1626	5.346e-85	316.0	COG1463@1|root,COG1463@2|Bacteria,2ICM7@201174|Actinobacteria,4CR1J@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158433_k127_1723775_2	1380390.JIAT01000011_gene2775	9.201e-130	433.0	COG1463@1|root,COG1463@2|Bacteria,2GMMT@201174|Actinobacteria,4CRZH@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158433_k127_1723775_8	882082.SaccyDRAFT_1231	1.679e-46	175.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_1723775_9	1304865.JAGF01000001_gene1440	8.19e-32	133.0	COG1669@1|root,COG1669@2|Bacteria,2GR6M@201174|Actinobacteria	201174|Actinobacteria	K	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,NTP_transf_2
SRR25158433_k127_1723775_10	326427.Cagg_3298	7.2e-17	84.0	COG2361@1|root,COG2361@2|Bacteria,2G9GH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158433_k127_1723775_0	469383.Cwoe_5915	2.527e-189	601.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CPAP@84995|Rubrobacteria	84995|Rubrobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158433_k127_1723775_11	929712.KI912613_gene540	6.461e-13	70.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria,4CQKR@84995|Rubrobacteria	84995|Rubrobacteria	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158433_k127_172974_0	469383.Cwoe_0824	9.196e-222	698.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CPN1@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158433_k127_172974_1	1380390.JIAT01000010_gene4173	1.294e-95	325.0	COG3677@1|root,COG3677@2|Bacteria,2HGBB@201174|Actinobacteria,4CTUD@84995|Rubrobacteria	84995|Rubrobacteria	K	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_172974_2	1123508.JH636440_gene2201	1.198e-47	185.0	28NVF@1|root,2ZBTI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1746217_3	926550.CLDAP_34190	2.25e-31	125.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158433_k127_1746217_1	649638.Trad_1534	1.047e-87	305.0	COG1840@1|root,COG1840@2|Bacteria,1WITN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158433_k127_1746217_0	266117.Rxyl_1174	2.494e-153	500.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158433_k127_1746217_2	1122939.ATUD01000002_gene1193	4.528e-33	148.0	COG1807@1|root,COG1807@2|Bacteria,2HJTU@201174|Actinobacteria,4CPVS@84995|Rubrobacteria	84995|Rubrobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1800111_1	469383.Cwoe_4548	1.02e-144	470.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CPKI@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158433_k127_1800111_3	469383.Cwoe_0202	8.713e-113	391.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CPQ8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158433_k127_1800111_5	926554.KI912637_gene3306	8.487e-101	337.0	COG0788@1|root,COG0788@2|Bacteria,1WJ8C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
SRR25158433_k127_1800111_6	1380390.JIAT01000010_gene4173	9.947e-53	190.0	COG3677@1|root,COG3677@2|Bacteria,2HGBB@201174|Actinobacteria,4CTUD@84995|Rubrobacteria	84995|Rubrobacteria	K	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1800111_7	1380390.JIAT01000009_gene2243	1.654e-25	112.0	COG3409@1|root,COG3409@2|Bacteria,2HQMS@201174|Actinobacteria,4CS7D@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Transglycosylas
SRR25158433_k127_1800111_4	469383.Cwoe_4554	4.078e-112	368.0	COG3294@1|root,COG3294@2|Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158433_k127_1800111_0	469383.Cwoe_4765	5.628e-148	491.0	29ZJM@1|root,30MJU@2|Bacteria,2HQSD@201174|Actinobacteria,4CSGF@84995|Rubrobacteria	84995|Rubrobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1800111_2	469383.Cwoe_4764	1.387e-131	455.0	COG0823@1|root,COG0823@2|Bacteria,2HR2G@201174|Actinobacteria,4CSXG@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1806377_0	215803.DB30_7448	1.499e-226	713.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158433_k127_1806377_2	469383.Cwoe_2888	6.01e-80	271.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4CPW4@84995|Rubrobacteria	84995|Rubrobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158433_k127_1806377_1	469383.Cwoe_2887	8.115e-153	501.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4CQZ9@84995|Rubrobacteria	84995|Rubrobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158433_k127_1810662_3	1283299.AUKG01000002_gene3996	7.75e-98	323.0	COG1960@1|root,COG1960@2|Bacteria,2GNBW@201174|Actinobacteria,4CS4D@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158433_k127_1810662_1	1123256.KB907931_gene2836	2.365e-162	528.0	COG1960@1|root,COG1960@2|Bacteria,1PUXP@1224|Proteobacteria,1RSAW@1236|Gammaproteobacteria,1X30E@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1810662_4	469383.Cwoe_0197	7.997e-96	332.0	COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,4CS7Q@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158433_k127_1810662_2	512565.AMIS_56280	2.211e-150	505.0	COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria,4D91M@85008|Micromonosporales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158433_k127_1810662_0	469383.Cwoe_0195	8.424e-212	666.0	COG0183@1|root,COG0183@2|Bacteria,2GJI8@201174|Actinobacteria,4CPYE@84995|Rubrobacteria	84995|Rubrobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158433_k127_1810662_5	68223.JNZY01000016_gene802	8.702e-05	45.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_1832445_1	469383.Cwoe_5293	1.381e-141	464.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158433_k127_1832445_7	1380390.JIAT01000009_gene815	4.735e-91	319.0	2AXGW@1|root,31PGJ@2|Bacteria,2HNNC@201174|Actinobacteria,4CPSP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1832445_12	448385.sce6726	2.345e-22	113.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1MUQC@1224|Proteobacteria,434JE@68525|delta/epsilon subdivisions,2WYWK@28221|Deltaproteobacteria,2Z0T7@29|Myxococcales	28221|Deltaproteobacteria	M	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M11,Reprolysin_5,RicinB_lectin_2
SRR25158433_k127_1832445_8	469383.Cwoe_0206	1.375e-65	233.0	COG3527@1|root,COG3527@2|Bacteria,2IBRH@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the alpha-acetolactate decarboxylase family	budA	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
SRR25158433_k127_1832445_5	469383.Cwoe_4649	7.189e-113	372.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CPI2@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158433_k127_1832445_6	929712.KI912613_gene2928	4.795e-92	319.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4CPJK@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158433_k127_1832445_0	469383.Cwoe_0897	1.016e-142	463.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4CSZZ@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158433_k127_1832445_15	443218.AS9A_4301	1.948e-13	77.0	COG0827@1|root,COG0827@2|Bacteria,2IA07@201174|Actinobacteria	201174|Actinobacteria	L	restriction endonuclease domain protein	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	BsuBI_PstI_RE
SRR25158433_k127_1832445_2	443218.AS9A_4300	1.471e-126	421.0	COG0827@1|root,COG0827@2|Bacteria,2IA5K@201174|Actinobacteria	201174|Actinobacteria	L	Eco57I restriction-modification methylase	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,MTS,N6_Mtase,PCMT,RrnaAD
SRR25158433_k127_1832445_10	443218.AS9A_4300	2.949e-37	151.0	COG0827@1|root,COG0827@2|Bacteria,2IA5K@201174|Actinobacteria	201174|Actinobacteria	L	Eco57I restriction-modification methylase	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,MTS,N6_Mtase,PCMT,RrnaAD
SRR25158433_k127_1832445_13	469383.Cwoe_1077	3.176e-22	102.0	2AUHF@1|root,31K5S@2|Bacteria,2HP4J@201174|Actinobacteria,4CQG4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1832445_11	1380390.JIAT01000009_gene510	5.722e-33	132.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4CQHQ@84995|Rubrobacteria	84995|Rubrobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158433_k127_1832445_14	1173029.JH980292_gene3103	6.756e-22	101.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1HC2P@1150|Oscillatoriales	1117|Cyanobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158433_k127_1832445_9	626887.J057_17015	5.512e-38	153.0	COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,1SFXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
SRR25158433_k127_1832445_3	1380390.JIAT01000011_gene2768	8.526e-120	403.0	COG0767@1|root,COG0767@2|Bacteria,2GJ27@201174|Actinobacteria,4CPTC@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158433_k127_1832445_4	929712.KI912613_gene4841	9.294e-114	378.0	COG0767@1|root,COG0767@2|Bacteria,2IAUN@201174|Actinobacteria,4CR2S@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158433_k127_1841507_3	469383.Cwoe_1791	3.858e-159	512.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CQ2U@84995|Rubrobacteria	84995|Rubrobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158433_k127_1841507_2	469383.Cwoe_1792	2.542e-168	542.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CPTX@84995|Rubrobacteria	84995|Rubrobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158433_k127_1841507_5	1380390.JIAT01000014_gene6225	2.066e-136	461.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4CPKK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158433_k127_1841507_8	1380390.JIAT01000014_gene6220	3.642e-94	317.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CQEJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158433_k127_1841507_1	880072.Desac_0973	0.0	1173.0	COG0286@1|root,COG0286@2|Bacteria,1MWUJ@1224|Proteobacteria,42NDU@68525|delta/epsilon subdivisions,2WU6S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	N-6 DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Mrr_cat_2,N6_Mtase,ResIII
SRR25158433_k127_1841507_17	551275.KB899547_gene283	0.0002279	49.0	COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2U6K6@28211|Alphaproteobacteria,43Y7K@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_1841507_0	562970.Btus_1793	0.0	1498.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,2785F@186823|Alicyclobacillaceae	91061|Bacilli	E	Glutamate synthase central domain	gltA2	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158433_k127_1841507_10	469383.Cwoe_1797	1.074e-44	170.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451,FHA,Yop-YscD_cpl
SRR25158433_k127_1841507_12	1283299.AUKG01000001_gene3079	2.853e-29	123.0	29VB2@1|root,30GR7@2|Bacteria,2HY8H@201174|Actinobacteria,4CQFR@84995|Rubrobacteria	84995|Rubrobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158433_k127_1841507_15	1283299.AUKG01000001_gene3080	3.141e-14	80.0	2AUMD@1|root,31KA7@2|Bacteria,2HP75@201174|Actinobacteria,4CQJE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1841507_7	469383.Cwoe_1801	4.576e-105	362.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,4CRTA@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158433_k127_1841507_6	469383.Cwoe_1802	9.675e-122	402.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CP5Z@84995|Rubrobacteria	84995|Rubrobacteria	O	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158433_k127_1841507_11	1122939.ATUD01000007_gene1988	7.996e-31	124.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4CQQK@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158433_k127_1841507_4	1380390.JIAT01000014_gene6239	3.413e-138	469.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CQIM@84995|Rubrobacteria	84995|Rubrobacteria	L	Exonuclease VII, large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158433_k127_1841507_13	1380390.JIAT01000014_gene6240	7.427e-21	103.0	COG1722@1|root,COG1722@2|Bacteria,2HRH7@201174|Actinobacteria,4CTGW@84995|Rubrobacteria	84995|Rubrobacteria	L	Exonuclease VII small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_VII_S
SRR25158433_k127_1841507_9	1136417.AZWE01000005_gene4642	1.595e-70	244.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria,4DM71@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158433_k127_1841507_16	1283299.AUKG01000003_gene390	1.428e-13	77.0	COG0346@1|root,COG0346@2|Bacteria,2HR81@201174|Actinobacteria,4CT42@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158433_k127_1841507_14	768704.Desmer_1347	4.728e-18	98.0	COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,1V2E4@1239|Firmicutes,24TKC@186801|Clostridia	186801|Clostridia	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158433_k127_1859677_3	1123508.JH636440_gene2200	2.697e-24	109.0	2CQVC@1|root,32SMW@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4365
SRR25158433_k127_1859677_5	491916.RHECIAT_CH0003093	1.799e-06	55.0	2AF53@1|root,3153U@2|Bacteria,1PV38@1224|Proteobacteria,2V39Q@28211|Alphaproteobacteria,4BKC2@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3892
SRR25158433_k127_1859677_4	482234.SCAZ3_03680	3.078e-13	74.0	COG1403@1|root,COG1403@2|Bacteria,1VBNY@1239|Firmicutes,4HM7N@91061|Bacilli	91061|Bacilli	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
SRR25158433_k127_1859677_1	1265310.CCBD010000047_gene2633	2.539e-90	307.0	COG2070@1|root,COG2070@2|Bacteria,2IADG@201174|Actinobacteria,235FT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158433_k127_1859677_2	469383.Cwoe_0826	5.039e-74	256.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4CQ5M@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158433_k127_1859677_0	1380390.JIAT01000009_gene1474	8.072e-197	627.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CPP3@84995|Rubrobacteria	84995|Rubrobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158433_k127_1875554_4	929712.KI912613_gene2016	8.221e-41	157.0	COG1443@1|root,COG1443@2|Bacteria	2|Bacteria	I	isopentenyl-diphosphate delta-isomerase activity	yfcD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.6.2,5.3.3.2	ko:K00949,ko:K01823	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R00619,R01123	RC00002,RC00017,RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_0565	NUDIX
SRR25158433_k127_1875554_7	1384484.AEQU_2078	0.0008791	47.0	COG1476@1|root,COG1476@2|Bacteria,2IGPZ@201174|Actinobacteria,4CVWM@84998|Coriobacteriia	84998|Coriobacteriia	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
SRR25158433_k127_1875554_3	469383.Cwoe_5941	1.833e-79	267.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158433_k127_1875554_2	1283299.AUKG01000001_gene1775	1.72e-112	371.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4CPJD@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158433_k127_1875554_0	469383.Cwoe_5940	1.487e-197	627.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CPBA@84995|Rubrobacteria	84995|Rubrobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158433_k127_1875554_1	469383.Cwoe_5938	7.278e-139	461.0	COG1524@1|root,COG1524@2|Bacteria,2HNGC@201174|Actinobacteria,4CPCH@84995|Rubrobacteria	84995|Rubrobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158433_k127_1875554_6	469383.Cwoe_5936	1.431e-23	106.0	2AU3I@1|root,31JPZ@2|Bacteria,2H277@201174|Actinobacteria,4CQ2S@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1876292_0	1380390.JIAT01000001_gene5084	1.366e-152	492.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_1876292_2	469383.Cwoe_0961	2.082e-89	307.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CRTX@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158433_k127_1876292_3	2002.JOEQ01000005_gene3794	3.433e-75	266.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria,4EKB6@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158433_k127_1876292_5	1051646.VITU9109_14061	1.357e-49	190.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,1R6VW@1224|Proteobacteria,1SNEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1876292_7	929712.KI912613_gene2094	5.602e-06	56.0	2AWPP@1|root,31NKK@2|Bacteria,2HR5H@201174|Actinobacteria,4CT0Y@84995|Rubrobacteria	84995|Rubrobacteria	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158433_k127_1876292_4	929712.KI912613_gene1711	7.968e-74	259.0	COG0491@1|root,COG0491@2|Bacteria,2IHG2@201174|Actinobacteria,4CTFT@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_1876292_1	469383.Cwoe_1779	4.77e-99	333.0	COG2247@1|root,COG2247@2|Bacteria,2I6I4@201174|Actinobacteria,4CU6H@84995|Rubrobacteria	84995|Rubrobacteria	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
SRR25158433_k127_1926872_0	469383.Cwoe_3725	1.678e-91	310.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CQ89@84995|Rubrobacteria	84995|Rubrobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158433_k127_1926872_2	469383.Cwoe_3722	1.604e-85	311.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4CPIX@84995|Rubrobacteria	84995|Rubrobacteria	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158433_k127_1926872_4	469383.Cwoe_3721	2.116e-25	107.0	COG1198@1|root,COG1198@2|Bacteria	2|Bacteria	L	DNA replication, synthesis of RNA primer	-	-	-	-	-	-	-	-	-	-	-	-	zinc-ribbons_6
SRR25158433_k127_1926872_1	469383.Cwoe_3720	1.084e-85	290.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158433_k127_1926872_6	1121372.AULK01000003_gene168	0.000299	53.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4FMX3@85023|Microbacteriaceae	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158433_k127_1926872_7	1380390.JIAT01000009_gene1359	0.000355	55.0	COG3391@1|root,COG3391@2|Bacteria,2GWAV@201174|Actinobacteria,4CRHS@84995|Rubrobacteria	84995|Rubrobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158433_k127_1926872_8	590998.Celf_2091	0.0008101	53.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158433_k127_1926872_3	1283299.AUKG01000001_gene3551	8.62e-47	195.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158433_k127_1926872_5	1283299.AUKG01000001_gene1590	1.31e-10	70.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1936078_1	1122939.ATUD01000003_gene3532	5.971e-131	428.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CPTP@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158433_k127_1936078_5	1380390.JIAT01000001_gene5113	1.223e-52	190.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CQII@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158433_k127_1936078_0	469383.Cwoe_4583	2.913e-148	486.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CPE0@84995|Rubrobacteria	84995|Rubrobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158433_k127_1936078_3	469383.Cwoe_4584	6.092e-85	297.0	COG0793@1|root,COG0793@2|Bacteria,2GKRP@201174|Actinobacteria,4CPMI@84995|Rubrobacteria	84995|Rubrobacteria	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158433_k127_1936078_4	469383.Cwoe_4586	1.096e-62	226.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CPSH@84995|Rubrobacteria	84995|Rubrobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158433_k127_1936078_2	469383.Cwoe_4587	7.313e-104	343.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CPHA@84995|Rubrobacteria	84995|Rubrobacteria	D	ATPases associated with a variety of cellular activities	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158433_k127_1937051_3	572479.Hprae_1690	8.147e-105	344.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WAE9@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158433_k127_1937051_5	469383.Cwoe_1335	2.361e-65	228.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4CQ35@84995|Rubrobacteria	84995|Rubrobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158433_k127_1937051_4	1283299.AUKG01000001_gene2625	8.903e-73	247.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CQ77@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158433_k127_1937051_6	469383.Cwoe_1330	1.191e-43	164.0	29XHR@1|root,30J8F@2|Bacteria,2HU87@201174|Actinobacteria,4CTU4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1937051_2	1122939.ATUD01000001_gene642	2.157e-193	624.0	COG2072@1|root,COG2072@2|Bacteria,2GMDH@201174|Actinobacteria,4CS42@84995|Rubrobacteria	84995|Rubrobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
SRR25158433_k127_1937051_8	744979.R2A130_3663	1.523e-08	64.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1937051_7	1380390.JIAT01000009_gene1326	2.694e-41	165.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158433_k127_1937051_0	469383.Cwoe_1328	0.0	1999.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CP97@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158433_k127_1937051_1	469383.Cwoe_1327	8.483e-207	650.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158433_k127_1939467_1	469383.Cwoe_4495	1.053e-121	394.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CP9Q@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158433_k127_1939467_3	1380390.JIAT01000001_gene4997	4.152e-85	294.0	COG0704@1|root,COG0704@2|Bacteria,2HGEG@201174|Actinobacteria,4CPTJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158433_k127_1939467_4	469383.Cwoe_4556	3.083e-66	236.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158433_k127_1939467_5	1122939.ATUD01000007_gene2084	3.331e-32	131.0	COG5607@1|root,COG5607@2|Bacteria,2HP25@201174|Actinobacteria,4CQD1@84995|Rubrobacteria	84995|Rubrobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158433_k127_1939467_6	1380390.JIAT01000001_gene5042	2.43e-22	107.0	COG5607@1|root,COG5607@2|Bacteria,2HP53@201174|Actinobacteria,4CQGX@84995|Rubrobacteria	84995|Rubrobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158433_k127_1939467_0	1380390.JIAT01000001_gene5016	4.314e-288	903.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2GIZG@201174|Actinobacteria,4CPGZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,PHP_C
SRR25158433_k127_1939467_2	1380390.JIAT01000001_gene5041	4.715e-118	387.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4CPPB@84995|Rubrobacteria	84995|Rubrobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158433_k127_1940161_1	29306.JOBE01000021_gene475	1.11e-165	529.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158433_k127_1940161_5	469383.Cwoe_5283	1.467e-90	324.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4CPHM@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158433_k127_1940161_4	469383.Cwoe_1890	2.577e-103	366.0	COG1363@1|root,COG1363@2|Bacteria,2I6I7@201174|Actinobacteria	201174|Actinobacteria	G	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158433_k127_1940161_0	469383.Cwoe_5284	3.005e-271	844.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CP7M@84995|Rubrobacteria	84995|Rubrobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158433_k127_1940161_3	469383.Cwoe_5285	4.022e-123	406.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CPGQ@84995|Rubrobacteria	84995|Rubrobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158433_k127_1940161_2	469383.Cwoe_5286	3.145e-130	431.0	COG2048@1|root,COG2048@2|Bacteria,2H014@201174|Actinobacteria,4CPAS@84995|Rubrobacteria	84995|Rubrobacteria	C	Cysteine-rich domain	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
SRR25158433_k127_1954553_0	469383.Cwoe_4760	9.703e-156	509.0	COG4447@1|root,COG4447@2|Bacteria,2HQI6@201174|Actinobacteria,4CS3J@84995|Rubrobacteria	84995|Rubrobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1954553_3	1283299.AUKG01000003_gene465	7.457e-59	224.0	2AXMN@1|root,31PMY@2|Bacteria,2HRZP@201174|Actinobacteria,4CRJJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1954553_4	1380390.JIAT01000001_gene4996	2.969e-27	114.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CPSW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158433_k127_1954553_1	1380390.JIAT01000001_gene5011	3.686e-86	294.0	COG0226@1|root,COG0226@2|Bacteria,2HNRT@201174|Actinobacteria,4CPZE@84995|Rubrobacteria	84995|Rubrobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158433_k127_1954553_2	1283299.AUKG01000002_gene4055	1.025e-81	280.0	COG0573@1|root,COG0573@2|Bacteria,2ISS5@201174|Actinobacteria,4CPV6@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158433_k127_1960651_15	287.DR97_440	1.339e-59	209.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1YG7R@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158433_k127_1960651_1	1242864.D187_005776	2.505e-168	538.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158433_k127_1960651_11	926564.KI911678_gene5257	3.219e-69	250.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4F492@85017|Promicromonosporaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158433_k127_1960651_2	469383.Cwoe_4727	4.351e-134	438.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CRSZ@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158433_k127_1960651_16	469383.Cwoe_1331	1.829e-58	214.0	2AVXX@1|root,31MS0@2|Bacteria,2HQEJ@201174|Actinobacteria,4CRZD@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mg_trans_NIPA
SRR25158433_k127_1960651_30	525909.Afer_1166	1.332e-24	117.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	relF	GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
SRR25158433_k127_1960651_26	525909.Afer_1167	1.218e-28	116.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
SRR25158433_k127_1960651_28	430998.XP_007677679.1	6.49e-25	117.0	2EQ4A@1|root,2ST70@2759|Eukaryota,3AADF@33154|Opisthokonta,3P8AF@4751|Fungi,3QYYA@4890|Ascomycota,204JB@147541|Dothideomycetes,3MNFK@451867|Dothideomycetidae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1960651_4	1380390.JIAT01000015_gene5820	2.549e-106	369.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4CPQF@84995|Rubrobacteria	84995|Rubrobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158433_k127_1960651_9	1380390.JIAT01000010_gene3992	2.309e-85	307.0	COG3685@1|root,COG3685@2|Bacteria,2HRWK@201174|Actinobacteria,4CTZZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158433_k127_1960651_29	591158.SSMG_04632	1.012e-24	106.0	COG3569@1|root,COG3569@2|Bacteria,2GJTH@201174|Actinobacteria	201174|Actinobacteria	L	DNA Topoisomerase	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158433_k127_1960651_35	710686.Mycsm_00697	1.727e-16	79.0	2BKZY@1|root,32FGR@2|Bacteria,2GZP6@201174|Actinobacteria,23C2C@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1960651_34	446462.Amir_3736	7.808e-18	98.0	COG1366@1|root,COG2172@1|root,COG2202@1|root,COG2203@1|root,COG2208@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GJSK@201174|Actinobacteria,4E0YZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c_2,PAS,PAS_3,STAS_2,SpoIIE
SRR25158433_k127_1960651_24	882083.SacmaDRAFT_5077	1.029e-35	149.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DXUF@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	fgd	-	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158433_k127_1960651_25	882083.SacmaDRAFT_5077	4.367e-35	138.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DXUF@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	fgd	-	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158433_k127_1960651_36	195250.CM001776_gene873	1.719e-15	81.0	2E5P1@1|root,330DP@2|Bacteria,1G84E@1117|Cyanobacteria,1H1KP@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SRR25158433_k127_1960651_32	632518.Calow_1394	3.531e-20	100.0	2E3EN@1|root,32YDN@2|Bacteria,1VDEB@1239|Firmicutes,24P1I@186801|Clostridia,42J95@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
SRR25158433_k127_1960651_20	748280.NH8B_0787	8.581e-43	163.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,2VWZD@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158433_k127_1960651_6	469383.Cwoe_1860	1.256e-91	320.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CPNM@84995|Rubrobacteria	84995|Rubrobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158433_k127_1960651_18	1283299.AUKG01000001_gene1940	3.229e-49	187.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158433_k127_1960651_14	1283299.AUKG01000001_gene2398	1.028e-60	213.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria,4CQNX@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158433_k127_1960651_8	1384054.N790_01460	1.218e-89	309.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1X53Q@135614|Xanthomonadales	135614|Xanthomonadales	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158433_k127_1960651_21	1380390.JIAT01000010_gene3985	1.829e-39	153.0	COG0711@1|root,COG0711@2|Bacteria,2HP0U@201174|Actinobacteria,4CQAI@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1960651_33	463191.SSEG_11358	4.466e-18	93.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158433_k127_1960651_19	1380390.JIAT01000010_gene3987	1.608e-43	171.0	29S2G@1|root,30D6Y@2|Bacteria,2HR27@201174|Actinobacteria,4CSWZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158433_k127_1960651_13	469383.Cwoe_5804	2.979e-62	223.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4CT3E@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158433_k127_1960651_31	1380390.JIAT01000013_gene120	1.796e-24	104.0	COG3369@1|root,COG3369@2|Bacteria,2HNFR@201174|Actinobacteria,4CQRA@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158433_k127_1960651_5	1150399.AQYK01000002_gene3691	2.665e-103	349.0	COG1215@1|root,COG1215@2|Bacteria,2IAQ1@201174|Actinobacteria,4FRE2@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
SRR25158433_k127_1960651_3	469383.Cwoe_2070	4.707e-113	375.0	28INB@1|root,2Z8NQ@2|Bacteria,2GM2K@201174|Actinobacteria	201174|Actinobacteria	S	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
SRR25158433_k127_1960651_0	1380390.JIAT01000010_gene4867	3.512e-193	647.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4CP77@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158433_k127_1960651_38	164757.Mjls_3382	7.237e-11	76.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,234JB@1762|Mycobacteriaceae	201174|Actinobacteria	E	permease	gabP	-	-	ko:K03293,ko:K11735,ko:K16237	-	-	-	-	ko00000,ko02000	2.A.3.1,2.A.3.1.12,2.A.3.1.4,2.A.3.1.5	-	iNJ661.Rv0522	AA_permease
SRR25158433_k127_1960651_37	469383.Cwoe_3833	5.891e-14	75.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4CS2X@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
SRR25158433_k127_1960651_27	469383.Cwoe_1320	6.21e-26	106.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CQU8@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158433_k127_1960651_39	929712.KI912613_gene4963	3.354e-06	55.0	COG0690@1|root,COG0690@2|Bacteria,2HQ1F@201174|Actinobacteria,4CRHK@84995|Rubrobacteria	84995|Rubrobacteria	U	SecE/Sec61-gamma subunits of protein translocation complex	-	-	-	-	-	-	-	-	-	-	-	-	SecE
SRR25158433_k127_1960651_10	469383.Cwoe_1322	2.843e-82	277.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CQ4I@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158433_k127_1960651_12	1380390.JIAT01000011_gene2555	1.968e-63	231.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4CQ3Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158433_k127_1960651_7	1380390.JIAT01000011_gene2556	1.067e-90	307.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CPV5@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158433_k127_1960651_17	469383.Cwoe_1325	7.174e-55	202.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CQ0J@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158433_k127_1960651_23	1380390.JIAT01000011_gene2558	4.496e-37	141.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4CQ9X@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158433_k127_1969276_3	222534.KB893757_gene4206	1.425e-25	109.0	COG4634@1|root,COG4634@2|Bacteria,2H1JU@201174|Actinobacteria,4EWAW@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1969276_6	1121019.AUMN01000020_gene1686	5.042e-21	94.0	COG2442@1|root,COG2442@2|Bacteria,2GQK1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158433_k127_1969276_7	1370120.AUWR01000035_gene1893	1.693e-16	90.0	2BEM9@1|root,328CR@2|Bacteria,2IM86@201174|Actinobacteria,23AFH@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1969276_4	1122939.ATUD01000021_gene4085	1.743e-23	102.0	2AUS7@1|root,31KF8@2|Bacteria,2HPA6@201174|Actinobacteria,4CQNH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158433_k127_1969276_1	42256.RradSPS_2206	1.643e-50	195.0	2EDR5@1|root,32UKZ@2|Bacteria,2ID1D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1969276_2	1449355.JQNR01000005_gene2530	3.05e-41	160.0	COG0457@1|root,COG0457@2|Bacteria	1449355.JQNR01000005_gene2530|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_1969276_0	1229780.BN381_350070	1.075e-50	199.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,3UXDN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Saccharopine dehydrogenase NADP binding domain	LYS1	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030312,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12445	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	Sacchrp_dh_NADP
SRR25158433_k127_1976619_9	469383.Cwoe_3035	4.645e-25	109.0	COG0816@1|root,COG0816@2|Bacteria,2HPE8@201174|Actinobacteria,4CQSC@84995|Rubrobacteria	84995|Rubrobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158433_k127_1976619_7	469383.Cwoe_3036	3.208e-67	243.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CQ8A@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158433_k127_1976619_6	469383.Cwoe_3037	1.429e-70	261.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CQ8W@84995|Rubrobacteria	84995|Rubrobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158433_k127_1976619_0	1380390.JIAT01000017_gene5276	1.033e-170	544.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CPJG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158433_k127_1976619_1	469383.Cwoe_3058	1.076e-151	496.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CPMA@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158433_k127_1976619_8	929712.KI912613_gene3456	3.329e-47	180.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CQJK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158433_k127_1976619_3	1283299.AUKG01000004_gene940	1.285e-101	350.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CPI6@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158433_k127_1976619_5	1283299.AUKG01000004_gene957	6.176e-77	273.0	COG2199@1|root,COG3706@2|Bacteria,2HFSA@201174|Actinobacteria,4CS6M@84995|Rubrobacteria	84995|Rubrobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158433_k127_1976619_2	1380390.JIAT01000009_gene1324	1.366e-119	394.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158433_k127_1976619_4	469383.Cwoe_4168	2.163e-96	322.0	COG0300@1|root,COG0300@2|Bacteria,2HF4X@201174|Actinobacteria,4CR1X@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_1976619_10	469383.Cwoe_1399	5.323e-11	76.0	COG3291@1|root,COG3291@2|Bacteria,2GPSB@201174|Actinobacteria,4CTYI@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158433_k127_1976619_11	1116375.VEJY3_20426	3.223e-06	51.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XTQN@135623|Vibrionales	135623|Vibrionales	M	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PKD,PPC,Peptidase_S8
SRR25158433_k127_1989516_4	469383.Cwoe_1570	2.455e-146	475.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CR0Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158433_k127_1989516_5	1380390.JIAT01000011_gene2669	1.441e-59	216.0	COG0132@1|root,COG0132@2|Bacteria,2GIZ2@201174|Actinobacteria,4CRYX@84995|Rubrobacteria	84995|Rubrobacteria	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SRR25158433_k127_1989516_1	469383.Cwoe_4177	1.102e-173	561.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_1989516_0	1449976.KALB_5959	5.426e-191	605.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4E0Y5@85010|Pseudonocardiales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158433_k127_1989516_2	1449976.KALB_5960	5.33e-161	514.0	COG1018@1|root,COG1018@2|Bacteria,2GJSW@201174|Actinobacteria,4E315@85010|Pseudonocardiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158433_k127_1989516_3	671143.DAMO_0475	2.201e-158	511.0	COG0161@1|root,COG0161@2|Bacteria,2NQY4@2323|unclassified Bacteria	2|Bacteria	H	Aminotransferase class-III	bioA	-	2.6.1.105,2.6.1.62	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231,R10699	RC00006,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iSB619.SA_RS12705	Aminotran_3
SRR25158433_k127_1989516_6	1380390.JIAT01000009_gene2043	4.753e-53	192.0	COG1595@1|root,COG1595@2|Bacteria,2HY6G@201174|Actinobacteria,4CQBA@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158433_k127_1989516_7	1380390.JIAT01000009_gene2042	5.966e-07	59.0	2B9NP@1|root,32312@2|Bacteria,2HP6G@201174|Actinobacteria,4CQIB@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158433_k127_2018027_16	1122609.AUGT01000003_gene2147	1.126e-09	70.0	COG2931@1|root,COG4733@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4347,He_PIG,HemolysinCabind,PATR,Peptidase_M10_C
SRR25158433_k127_2018027_11	1122939.ATUD01000005_gene2768	9.006e-50	181.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158433_k127_2018027_3	469383.Cwoe_3259	6.53e-164	528.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CPXQ@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158433_k127_2018027_10	485913.Krac_0576	1.074e-64	233.0	COG0451@1|root,COG0451@2|Bacteria,2G8UC@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158433_k127_2018027_7	469383.Cwoe_4192	1.91e-92	327.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CPW8@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_2018027_15	861299.J421_1782	2.684e-15	86.0	COG4454@1|root,COG4454@2|Bacteria,1ZTKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2018027_8	596154.Alide2_4303	3.752e-92	321.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2VK2U@28216|Betaproteobacteria,4AC4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	TIGRFAM HipA, N-terminal	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
SRR25158433_k127_2018027_17	1121866.AUGK01000015_gene1985	2.019e-08	59.0	COG1396@1|root,COG1396@2|Bacteria,2HWFD@201174|Actinobacteria,4CYBT@84998|Coriobacteriia	84998|Coriobacteriia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158433_k127_2018027_2	469383.Cwoe_3257	2.356e-180	571.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158433_k127_2018027_6	469383.Cwoe_3256	1.37e-105	349.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CQMD@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158433_k127_2018027_9	469383.Cwoe_3255	2.749e-73	254.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CQW4@84995|Rubrobacteria	84995|Rubrobacteria	J	IPP transferase	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158433_k127_2018027_0	469383.Cwoe_3249	6.494e-212	665.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158433_k127_2018027_4	1283299.AUKG01000002_gene5161	5.874e-161	516.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CPF2@84995|Rubrobacteria	84995|Rubrobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158433_k127_2018027_14	929712.KI912613_gene2255	1.064e-17	94.0	COG1514@1|root,COG1514@2|Bacteria,2HNKJ@201174|Actinobacteria,4CQT5@84995|Rubrobacteria	84995|Rubrobacteria	J	LigT like Phosphoesterase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158433_k127_2018027_5	710687.KI912270_gene1010	3.468e-151	491.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,232Q5@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158433_k127_2018027_12	1380390.JIAT01000010_gene4817	2.668e-32	137.0	COG1426@1|root,COG1426@2|Bacteria,2HNYG@201174|Actinobacteria,4CQ7X@84995|Rubrobacteria	84995|Rubrobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
SRR25158433_k127_2018027_1	1283299.AUKG01000002_gene5165	9.362e-204	659.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158433_k127_2018027_13	1283299.AUKG01000003_gene334	1.017e-24	112.0	COG4942@1|root,COG4942@2|Bacteria,2HNNM@201174|Actinobacteria,4CPT2@84995|Rubrobacteria	84995|Rubrobacteria	D	Transglycosylase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglycosylas
SRR25158433_k127_2052614_3	419947.MRA_2576	2.285e-40	156.0	COG1487@1|root,COG1487@2|Bacteria,2IR5C@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_2052614_2	1206725.BAFU01000246_gene2436	2.644e-41	159.0	COG2020@1|root,COG2020@2|Bacteria,2IP2M@201174|Actinobacteria,4G4WC@85025|Nocardiaceae	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158433_k127_2052614_8	1380390.JIAT01000010_gene4645	1.356e-18	96.0	COG2931@1|root,COG2931@2|Bacteria,2IGYS@201174|Actinobacteria	201174|Actinobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158433_k127_2052614_9	469383.Cwoe_5214	4.046e-14	80.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	MA20_25230	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158433_k127_2052614_0	1206731.BAGB01000040_gene7920	5.273e-52	187.0	COG0346@1|root,COG0346@2|Bacteria,2IPQW@201174|Actinobacteria	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158433_k127_2052614_4	1122939.ATUD01000002_gene1179	9.631e-40	157.0	COG0625@1|root,COG0625@2|Bacteria,2HQWF@201174|Actinobacteria,4CSPC@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158433_k127_2052614_1	236097.ADG881_3073	3.783e-50	190.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1S2Y7@1236|Gammaproteobacteria,1XMBV@135619|Oceanospirillales	135619|Oceanospirillales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158433_k127_2052614_6	1122939.ATUD01000002_gene1179	2.512e-29	125.0	COG0625@1|root,COG0625@2|Bacteria,2HQWF@201174|Actinobacteria,4CSPC@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158433_k127_207635_8	469383.Cwoe_2623	9.166e-28	115.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	CBS,GGDEF,HisKA,SpoIIE
SRR25158433_k127_207635_6	1283299.AUKG01000001_gene1596	2.215e-42	168.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	cysR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,PAS,cNMP_binding
SRR25158433_k127_207635_0	1283299.AUKG01000001_gene2083	6.562e-163	549.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_207635_4	1283299.AUKG01000001_gene3466	2.423e-68	254.0	COG0642@1|root,COG2205@2|Bacteria,2I3JI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158433_k127_207635_3	1283299.AUKG01000001_gene3465	3.49e-79	275.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4CT02@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158433_k127_207635_1	1283299.AUKG01000004_gene1048	7.856e-137	455.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,2GKDT@201174|Actinobacteria,4CS52@84995|Rubrobacteria	84995|Rubrobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRR25158433_k127_207635_5	469383.Cwoe_2962	1.818e-42	162.0	COG4315@1|root,COG4315@2|Bacteria	2|Bacteria	P	Pfam Secreted repeat of	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158433_k127_207635_10	1463895.JODA01000023_gene4194	1.202e-08	67.0	2A0GH@1|root,30NKB@2|Bacteria,2H1ZE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_207635_9	1394178.AWOO02000001_gene1301	4.993e-21	107.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EP58@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158433_k127_207635_2	1122939.ATUD01000004_gene3867	3.886e-116	388.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158433_k127_207635_7	1380390.JIAT01000009_gene850	2.47e-38	154.0	COG0739@1|root,COG0739@2|Bacteria,2HP3A@201174|Actinobacteria,4CQEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M23
SRR25158433_k127_2101954_0	1380390.JIAT01000011_gene2565	0.0	1281.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158433_k127_2101954_1	469383.Cwoe_1326	2.506e-27	112.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4CQ9X@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158433_k127_2102797_4	1283299.AUKG01000001_gene2682	3.949e-61	227.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CQ4E@84995|Rubrobacteria	84995|Rubrobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158433_k127_2102797_0	469383.Cwoe_1370	2.175e-236	762.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CPFU@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158433_k127_2102797_2	1380390.JIAT01000011_gene2622	3.033e-90	304.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4CQ4H@84995|Rubrobacteria	84995|Rubrobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158433_k127_2102797_6	1247963.JPHU01000002_gene2496	2.667e-29	132.0	COG1216@1|root,COG1216@2|Bacteria,1R5GW@1224|Proteobacteria,2TTEN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158433_k127_2102797_3	1089551.KE386572_gene4426	3.369e-65	243.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,2U12I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158433_k127_2102797_7	1463864.JOGO01000038_gene2427	7.272e-06	59.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase	-	-	1.1.1.384	ko:K13327	ko00523,ko01130,map00523,map01130	M00801,M00802	R05526	RC00897	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158433_k127_2102797_5	575540.Isop_0600	5.085e-57	210.0	COG1216@1|root,COG1216@2|Bacteria,2IZFD@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_2102797_1	1380390.JIAT01000014_gene6281	2.818e-178	571.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4CQXX@84995|Rubrobacteria	84995|Rubrobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158433_k127_2125886_7	717785.HYPMC_1707	0.0002429	45.0	2DGHW@1|root,2ZW1T@2|Bacteria,1P867@1224|Proteobacteria,2UWAZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2125886_5	685727.REQ_07220	6.47e-34	136.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,4G0XD@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158433_k127_2125886_1	469383.Cwoe_5366	2.484e-149	509.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CPPG@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158433_k127_2125886_2	1380390.JIAT01000013_gene38	3.866e-122	401.0	COG1469@1|root,COG1469@2|Bacteria,2HPYB@201174|Actinobacteria,4CRDI@84995|Rubrobacteria	84995|Rubrobacteria	S	Type I GTP cyclohydrolase folE2	-	-	-	-	-	-	-	-	-	-	-	-	GCHY-1
SRR25158433_k127_2125886_3	469383.Cwoe_5368	5.323e-61	216.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CQIK@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158433_k127_2125886_0	1380390.JIAT01000010_gene4161	7.772e-223	718.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CRS8@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158433_k127_2125886_6	266117.Rxyl_1665	1.498e-05	54.0	COG1633@1|root,COG1633@2|Bacteria,2GQ6Z@201174|Actinobacteria,4CU3W@84995|Rubrobacteria	84995|Rubrobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158433_k127_2125886_4	1380390.JIAT01000010_gene4090	1.32e-40	157.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158433_k127_2163173_9	1380390.JIAT01000009_gene1700	3.052e-98	338.0	COG3307@1|root,COG3307@2|Bacteria,2IDMZ@201174|Actinobacteria,4CRI9@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158433_k127_2163173_18	1122939.ATUD01000013_gene852	1.012e-15	87.0	COG0823@1|root,COG0823@2|Bacteria,2HNKQ@201174|Actinobacteria,4CPPF@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
SRR25158433_k127_2163173_0	469383.Cwoe_0086	4.472e-204	652.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4CP9E@84995|Rubrobacteria	84995|Rubrobacteria	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158433_k127_2163173_14	1380390.JIAT01000009_gene1710	8.138e-69	245.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4CSIG@84995|Rubrobacteria	84995|Rubrobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158433_k127_2163173_11	469383.Cwoe_0081	8.781e-83	294.0	COG1968@1|root,COG1968@2|Bacteria,2HNYX@201174|Actinobacteria,4CTDI@84995|Rubrobacteria	84995|Rubrobacteria	V	Bacitracin resistance protein BacA	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158433_k127_2163173_4	748247.AZKH_4576	9.504e-127	419.0	COG3177@1|root,COG3177@2|Bacteria,1QRKG@1224|Proteobacteria,2VPMZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_DeoR
SRR25158433_k127_2163173_7	1283299.AUKG01000001_gene1683	6.44e-106	354.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CP9S@84995|Rubrobacteria	84995|Rubrobacteria	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158433_k127_2163173_2	1283299.AUKG01000001_gene1742	3.659e-142	466.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158433_k127_2163173_5	929712.KI912613_gene989	4.082e-121	432.0	COG1131@1|root,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,4CSAQ@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
SRR25158433_k127_2163173_15	1370121.AUWS01000034_gene4141	2.878e-60	232.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,23296@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158433_k127_2163173_8	929712.KI912613_gene1138	5.08e-104	358.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CPG5@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158433_k127_2163173_3	1380390.JIAT01000009_gene1776	1.225e-136	456.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158433_k127_2163173_6	469383.Cwoe_0016	1.115e-118	415.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CP9M@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158433_k127_2163173_1	469383.Cwoe_0015	1.078e-174	560.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CPCV@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158433_k127_2163173_10	469383.Cwoe_0014	6.085e-93	319.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158433_k127_2163173_16	1283299.AUKG01000001_gene1750	1.772e-30	126.0	COG1716@1|root,COG1716@2|Bacteria,2HM1E@201174|Actinobacteria,4CQ7B@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158433_k127_2163173_12	469383.Cwoe_0012	2.944e-78	269.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158433_k127_2163173_13	1380390.JIAT01000009_gene1782	1.365e-73	261.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CR9T@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158433_k127_2163173_19	469383.Cwoe_0010	5.268e-07	55.0	2AVPF@1|root,31MGI@2|Bacteria,2HE2U@201174|Actinobacteria,4CQ1U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2164182_9	1173264.KI913949_gene1553	4.718e-27	115.0	COG4113@1|root,COG4113@2|Bacteria,1G7F7@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_2164182_3	875328.JDM601_0685	1.104e-90	312.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,234Y8@1762|Mycobacteriaceae	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158433_k127_2164182_4	649831.L083_2644	1.726e-79	276.0	COG5637@1|root,COG5637@2|Bacteria,2GP5P@201174|Actinobacteria,4DHPP@85008|Micromonosporales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158433_k127_2164182_1	2002.JOEQ01000037_gene4324	2.002e-191	619.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4EFZC@85012|Streptosporangiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158433_k127_2164182_5	1157943.KB892706_gene4128	1.919e-67	237.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,235ZG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158433_k127_2164182_6	221288.JH992901_gene2537	8.141e-49	184.0	COG2304@1|root,COG2304@2|Bacteria,1GBBJ@1117|Cyanobacteria	2|Bacteria	S	PFAM Common central domain of tyrosinase	-	-	1.14.18.1	ko:K00505,ko:K02674	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	-	-	-	Neisseria_PilC,Tyrosinase,VWA_2
SRR25158433_k127_2164182_10	221288.JH992901_gene2536	1.749e-17	89.0	28MNK@1|root,2ZAY4@2|Bacteria	2|Bacteria	-	-	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	Tyrosinase
SRR25158433_k127_2164182_8	525904.Tter_2415	6.425e-37	157.0	COG2843@1|root,COG2843@2|Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	CarboxypepD_reg,PGA_cap,Peptidase_M15_4
SRR25158433_k127_2164182_7	1122939.ATUD01000008_gene2441	9.798e-48	192.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4CSZW@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
SRR25158433_k127_2164182_2	1380390.JIAT01000009_gene2062	2.203e-105	365.0	COG3481@1|root,COG3481@2|Bacteria,2IRFS@201174|Actinobacteria,4CPMU@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD
SRR25158433_k127_2164182_0	469383.Cwoe_5785	6.991e-220	696.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4CPJ7@84995|Rubrobacteria	84995|Rubrobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158433_k127_2165356_5	469383.Cwoe_1691	2.857e-114	378.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CP99@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158433_k127_2165356_14	1380390.JIAT01000014_gene6271	6.227e-61	224.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CPWF@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158433_k127_2165356_8	469383.Cwoe_1693	6.319e-96	319.0	COG1595@1|root,COG1595@2|Bacteria,2HQ0U@201174|Actinobacteria,4CRGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158433_k127_2165356_17	441620.Mpop_1852	6.178e-39	156.0	2F3GP@1|root,33WAD@2|Bacteria,1NWJ1@1224|Proteobacteria,2USQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2165356_4	1173021.ALWA01000034_gene4251	1.512e-138	458.0	COG0270@1|root,COG0270@2|Bacteria,1FZVI@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
SRR25158433_k127_2165356_16	1051632.TPY_0065	3.037e-42	160.0	COG3727@1|root,COG3727@2|Bacteria,1VHVP@1239|Firmicutes,24RFY@186801|Clostridia	186801|Clostridia	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
SRR25158433_k127_2165356_3	675635.Psed_2775	4.893e-141	455.0	COG0454@1|root,COG0456@2|Bacteria,2H994@201174|Actinobacteria	201174|Actinobacteria	H	sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2165356_10	1380390.JIAT01000011_gene2334	2.202e-81	287.0	28MY8@1|root,32YD0@2|Bacteria,2HR9A@201174|Actinobacteria,4CT5U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2165356_6	469383.Cwoe_4746	2.818e-107	376.0	COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158433_k127_2165356_15	1380390.JIAT01000015_gene5805	6.02e-49	194.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CSII@84995|Rubrobacteria	84995|Rubrobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158433_k127_2165356_2	1283299.AUKG01000001_gene3035	9.764e-166	538.0	COG0204@1|root,COG0240@1|root,COG0204@2|Bacteria,COG0240@2|Bacteria,2GJ6V@201174|Actinobacteria,4CP70@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158433_k127_2165356_11	469383.Cwoe_1762	1.328e-75	257.0	COG1595@1|root,COG1595@2|Bacteria,2HG39@201174|Actinobacteria,4CP8K@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158433_k127_2165356_19	929712.KI912613_gene4770	1.157e-17	86.0	2AWQX@1|root,31NMV@2|Bacteria,2HR6S@201174|Actinobacteria,4CT2Q@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2165356_20	452863.Achl_0752	3.155e-16	85.0	2C9IE@1|root,31AT3@2|Bacteria,2IM6M@201174|Actinobacteria,1WBKC@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158433_k127_2165356_12	469383.Cwoe_1764	5.285e-72	253.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CQ6Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRR25158433_k127_2165356_9	469383.Cwoe_1767	1.161e-87	299.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158433_k127_2165356_1	1380390.JIAT01000014_gene6249	1.038e-170	545.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158433_k127_2165356_13	1380390.JIAT01000014_gene6246	3.063e-67	238.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4CPNR@84995|Rubrobacteria	84995|Rubrobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
SRR25158433_k127_2165356_0	1394178.AWOO02000001_gene1514	4.916e-201	631.0	COG0183@1|root,COG0183@2|Bacteria,2IBJU@201174|Actinobacteria	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158433_k127_2165356_7	710687.KI912270_gene1894	7.305e-105	357.0	COG4977@1|root,COG4977@2|Bacteria,2GM0M@201174|Actinobacteria,2362H@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158433_k127_2165356_18	1169152.AXVD01000038_gene1712	6.081e-21	105.0	COG1418@1|root,COG1418@2|Bacteria,2GQET@201174|Actinobacteria,4FYA4@85025|Nocardiaceae	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158433_k127_2176334_0	253839.SSNG_07463	0.0	2121.0	COG0604@1|root,COG3321@1|root,COG0604@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	ko:K12436	-	-	-	-	ko00000,ko01004	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_2177113_0	1157640.AQWO01000016_gene901	0.0	1267.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_2202749_4	1297742.A176_04209	2.447e-132	461.0	2CAPJ@1|root,2Z90A@2|Bacteria,1P1EA@1224|Proteobacteria,4389Z@68525|delta/epsilon subdivisions,2X3JE@28221|Deltaproteobacteria,2YWBF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2202749_19	198628.Dda3937_04176	6.172e-13	81.0	2DTWK@1|root,33MZR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2202749_12	886293.Sinac_0530	1.306e-63	222.0	COG0262@1|root,COG0262@2|Bacteria,2IYX1@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158433_k127_2202749_9	710111.FraQA3DRAFT_2762	3.082e-88	298.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria,4ESXR@85013|Frankiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158433_k127_2202749_17	469383.Cwoe_2685	8.183e-35	139.0	COG1917@1|root,COG1917@2|Bacteria,2H15W@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_2202749_20	1370120.AUWR01000030_gene3726	4.755e-12	69.0	COG4453@1|root,COG4453@2|Bacteria,2IPNF@201174|Actinobacteria,239ZX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
SRR25158433_k127_2202749_15	396588.Tgr7_0919	2.938e-47	175.0	COG3153@1|root,COG3153@2|Bacteria,1QUSG@1224|Proteobacteria,1T29M@1236|Gammaproteobacteria,1WYU3@135613|Chromatiales	135613|Chromatiales	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158433_k127_2202749_1	429009.Adeg_1669	1.877e-208	666.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,42EQA@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158433_k127_2202749_11	469383.Cwoe_3622	1.891e-78	268.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CQ6T@84995|Rubrobacteria	84995|Rubrobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158433_k127_2202749_7	1380390.JIAT01000014_gene6290	6.6e-114	379.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4CTCM@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158433_k127_2202749_18	469383.Cwoe_3620	5.736e-19	89.0	COG0291@1|root,COG0291@2|Bacteria,2HPDV@201174|Actinobacteria,4CQRX@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158433_k127_2202749_16	1380390.JIAT01000010_gene4414	5.881e-38	148.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4CQE4@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158433_k127_2202749_13	469383.Cwoe_3618	3.908e-58	211.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CPWM@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA rRNA methyltransferase, SpoU	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158433_k127_2202749_3	469383.Cwoe_3617	2.506e-139	454.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CPUG@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158433_k127_2202749_2	1121430.JMLG01000012_gene1991	5.735e-174	585.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,2602M@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
SRR25158433_k127_2202749_5	469383.Cwoe_3615	2.112e-122	402.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CPXE@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158433_k127_2202749_10	1283299.AUKG01000002_gene4808	7.055e-84	292.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CPB9@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158433_k127_2202749_6	469383.Cwoe_3613	7.466e-118	391.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CPHD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158433_k127_2202749_8	1089553.Tph_c25450	1.649e-99	338.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,42F28@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158433_k127_2202749_0	469383.Cwoe_3610	7.655e-225	707.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CPRP@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158433_k127_2231650_8	479434.Sthe_0784	2.731e-05	51.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi,27Y4R@189775|Thermomicrobia	189775|Thermomicrobia	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158433_k127_2231650_0	469383.Cwoe_1538	3.274e-230	735.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158433_k127_2231650_7	469383.Cwoe_5937	6.601e-37	144.0	COG2246@1|root,COG2246@2|Bacteria,2HR1U@201174|Actinobacteria,4CSWB@84995|Rubrobacteria	84995|Rubrobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158433_k127_2231650_2	469383.Cwoe_2922	4.249e-217	689.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158433_k127_2231650_1	469383.Cwoe_2921	3.177e-221	713.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPT4@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158433_k127_2231650_3	469383.Cwoe_2913	4.553e-136	459.0	COG0446@1|root,COG0446@2|Bacteria,2H2SC@201174|Actinobacteria,4CRSC@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
SRR25158433_k127_2231650_4	1122939.ATUD01000004_gene3716	4.082e-96	319.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CPKV@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158433_k127_2231650_5	1380390.JIAT01000016_gene5499	1.949e-54	198.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,4CQ18@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR25158433_k127_2231650_6	1283299.AUKG01000004_gene1080	6.589e-52	190.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2HF4S@201174|Actinobacteria,4CPSY@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
SRR25158433_k127_2245447_22	1380390.JIAT01000009_gene362	2.438e-14	74.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158433_k127_2245447_15	1380390.JIAT01000009_gene363	7.018e-71	250.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria	201174|Actinobacteria	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158433_k127_2245447_2	1380390.JIAT01000009_gene364	6.67e-239	754.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158433_k127_2245447_8	469383.Cwoe_4628	6.871e-121	400.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CQIN@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase, family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158433_k127_2245447_23	469383.Cwoe_4625	1.866e-09	63.0	2A1TX@1|root,30Q2V@2|Bacteria,2HR8N@201174|Actinobacteria,4CT50@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2245447_11	1283299.AUKG01000002_gene3884	1.553e-103	347.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CR6B@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase A chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_A
SRR25158433_k127_2245447_19	1380390.JIAT01000009_gene345	2.649e-28	115.0	COG0636@1|root,COG0636@2|Bacteria,2HPGR@201174|Actinobacteria,4CQV2@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158433_k127_2245447_17	1283299.AUKG01000002_gene3886	2.058e-47	177.0	COG0711@1|root,COG0711@2|Bacteria,2HGFF@201174|Actinobacteria,4CQKE@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158433_k127_2245447_16	469383.Cwoe_4621	1.182e-58	214.0	COG0712@1|root,COG0712@2|Bacteria,2HNXP@201174|Actinobacteria,4CQ6B@84995|Rubrobacteria	84995|Rubrobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158433_k127_2245447_1	469383.Cwoe_4620	3.045e-245	767.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CP6C@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158433_k127_2245447_10	1283299.AUKG01000002_gene3889	2.001e-106	353.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CPD1@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158433_k127_2245447_3	929712.KI912613_gene2882	7.623e-230	719.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CP9Y@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158433_k127_2245447_18	1283299.AUKG01000002_gene3891	3.748e-30	138.0	COG0355@1|root,COG0355@2|Bacteria,2HPEY@201174|Actinobacteria,4CQTA@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158433_k127_2245447_5	469383.Cwoe_4616	1.393e-141	458.0	COG0624@1|root,COG0624@2|Bacteria,2I9GD@201174|Actinobacteria,4CPM7@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158433_k127_2245447_14	1283299.AUKG01000002_gene3898	1.941e-92	326.0	COG1316@1|root,COG1316@2|Bacteria,2HJ7K@201174|Actinobacteria,4CPJT@84995|Rubrobacteria	84995|Rubrobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158433_k127_2245447_7	1284352.AOIG01000009_gene1718	1.976e-123	409.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,26Q8V@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158433_k127_2245447_12	1283299.AUKG01000002_gene3900	1.872e-96	333.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158433_k127_2245447_13	469383.Cwoe_4612	4.447e-96	324.0	COG2222@1|root,COG2222@2|Bacteria,2IN5A@201174|Actinobacteria,4CP71@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
SRR25158433_k127_2245447_24	1246448.ANAZ01000022_gene1981	1.647e-06	58.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158433_k127_2245447_4	469383.Cwoe_4609	9.046e-178	567.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4CS1V@84995|Rubrobacteria	84995|Rubrobacteria	H	S-adenosyl-L-homocysteine hydrolase	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158433_k127_2245447_9	469383.Cwoe_4603	7.373e-109	362.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPY2@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158433_k127_2245447_21	1123229.AUBC01000009_gene317	2.87e-15	84.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,3JW65@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158433_k127_2245447_20	1283299.AUKG01000002_gene3911	1.506e-24	112.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CQU6@84995|Rubrobacteria	84995|Rubrobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158433_k127_2245447_0	1394178.AWOO02000005_gene3609	1.065e-285	905.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4EGCZ@85012|Streptosporangiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158433_k127_2245447_6	1380390.JIAT01000001_gene5131	4.197e-138	446.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CPCP@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158433_k127_229918_1	1144275.COCOR_02848	1.543e-101	336.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,43BJ4@68525|delta/epsilon subdivisions,2WMCV@28221|Deltaproteobacteria,2YXIN@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158433_k127_229918_3	1089545.KB913037_gene438	2.619e-16	94.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin-like,DUF4157,PKD,SLH
SRR25158433_k127_229918_0	103733.JNYO01000081_gene4572	4.762e-134	462.0	COG3209@1|root,COG5412@1|root,COG3209@2|Bacteria,COG5412@2|Bacteria,2IB04@201174|Actinobacteria,4E15Y@85010|Pseudonocardiales	201174|Actinobacteria	M	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
SRR25158433_k127_229918_6	1430331.EP10_16345	4.424e-07	64.0	COG5444@1|root,COG5444@2|Bacteria,1V6QC@1239|Firmicutes,4HJCF@91061|Bacilli	91061|Bacilli	L	DNA/RNA non-specific endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2
SRR25158433_k127_229918_2	469383.Cwoe_4971	4.826e-66	233.0	COG3629@1|root,COG3629@2|Bacteria,2IC17@201174|Actinobacteria	201174|Actinobacteria	T	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158433_k127_229918_4	469383.Cwoe_0918	1.058e-13	80.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4CS1F@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158433_k127_229918_5	469383.Cwoe_0702	2.057e-10	71.0	2B5BB@1|root,31Y5H@2|Bacteria,2HR45@201174|Actinobacteria,4CSZH@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2309717_6	1120949.KB903301_gene6312	7.464e-08	63.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4D9K3@85008|Micromonosporales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
SRR25158433_k127_2309717_2	469383.Cwoe_3795	3.092e-95	316.0	COG0176@1|root,COG0176@2|Bacteria,2GSF7@201174|Actinobacteria,4CR7E@84995|Rubrobacteria	84995|Rubrobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158433_k127_2309717_0	1283299.AUKG01000002_gene4594	3.942e-191	621.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4CPYZ@84995|Rubrobacteria	84995|Rubrobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DAO_C
SRR25158433_k127_2309717_4	929712.KI912613_gene816	5.041e-55	200.0	COG0778@1|root,COG0778@2|Bacteria,2HRX2@201174|Actinobacteria,4CU07@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158433_k127_2309717_1	469383.Cwoe_3798	6.782e-116	399.0	COG1657@1|root,COG4720@1|root,COG1657@2|Bacteria,COG4720@2|Bacteria,2HPSE@201174|Actinobacteria,4CR5W@84995|Rubrobacteria	84995|Rubrobacteria	I	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	-
SRR25158433_k127_2309717_3	469383.Cwoe_3799	9.026e-71	248.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158433_k127_2379077_2	1380390.JIAT01000009_gene2137	3.95e-117	404.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158433_k127_2379077_1	1122939.ATUD01000011_gene2257	2.321e-117	391.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CPVD@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158433_k127_2379077_4	1122939.ATUD01000011_gene2253	6.243e-86	289.0	COG0637@1|root,COG0637@2|Bacteria,2I6IT@201174|Actinobacteria,4CRIS@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158433_k127_2379077_3	43354.JOIJ01000001_gene235	6.646e-102	357.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4DZR1@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158433_k127_2379077_0	266117.Rxyl_2464	2.152e-171	558.0	COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria,4CP7I@84995|Rubrobacteria	84995|Rubrobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158433_k127_2379077_5	1122939.ATUD01000011_gene2292	6.708e-59	215.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CPKG@84995|Rubrobacteria	84995|Rubrobacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRR25158433_k127_2407088_6	365528.KB891219_gene888	1.385e-69	241.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4EVS8@85013|Frankiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158433_k127_2407088_7	67257.JODR01000020_gene5351	1.223e-24	119.0	COG0477@1|root,COG2814@2|Bacteria,2IA1T@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_2407088_0	469383.Cwoe_5268	1.138e-236	741.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CP9U@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158433_k127_2407088_9	469383.Cwoe_5267	2.022e-20	97.0	COG2331@1|root,COG2331@2|Bacteria,2HGE7@201174|Actinobacteria,4CQV7@84995|Rubrobacteria	84995|Rubrobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158433_k127_2407088_8	266117.Rxyl_1540	3.444e-24	119.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CPSE@84995|Rubrobacteria	84995|Rubrobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158433_k127_2407088_4	469383.Cwoe_5264	2.2e-92	331.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158433_k127_2407088_5	469383.Cwoe_5263	4.778e-83	296.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CQ57@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158433_k127_2407088_1	469383.Cwoe_5259	6.165e-224	703.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CQ79@84995|Rubrobacteria	84995|Rubrobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158433_k127_2407088_10	1380390.JIAT01000009_gene1464	1.22e-16	94.0	COG2367@1|root,COG2367@2|Bacteria,2HMJZ@201174|Actinobacteria,4CQCV@84995|Rubrobacteria	84995|Rubrobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SRR25158433_k127_2407088_3	797209.ZOD2009_07344	1.115e-133	436.0	COG1304@1|root,arCOG00613@2157|Archaea,2XTFQ@28890|Euryarchaeota,23TJ6@183963|Halobacteria	183963|Halobacteria	H	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	-	-	1.13.12.4	ko:K00467	ko00620,map00620	-	R00319	RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158433_k127_2407088_2	37919.EP51_26205	3.102e-175	564.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4FUME@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158433_k127_243997_14	1380390.JIAT01000012_gene3255	0.0001398	49.0	2DBIT@1|root,2Z9GU@2|Bacteria	2|Bacteria	S	Carotene biosynthesis associated membrane protein	mptA	GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
SRR25158433_k127_243997_13	28444.JODQ01000002_gene4195	2.126e-08	66.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4EHA8@85012|Streptosporangiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158433_k127_243997_6	1380390.JIAT01000009_gene1866	5.831e-65	241.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4CQGK@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158433_k127_243997_4	1283299.AUKG01000001_gene1828	2.483e-97	327.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CU2Q@84995|Rubrobacteria	84995|Rubrobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158433_k127_243997_5	469383.Cwoe_5906	3.442e-79	280.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2I53J@201174|Actinobacteria,4CRVJ@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158433_k127_243997_3	1380390.JIAT01000009_gene1861	9.392e-112	377.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPH3@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158433_k127_243997_1	1380390.JIAT01000009_gene1860	8.914e-182	578.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4CPFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158433_k127_243997_0	469383.Cwoe_5909	1.825e-210	663.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4CPJV@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase, family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158433_k127_243997_11	469383.Cwoe_5910	4.059e-15	83.0	COG0360@1|root,COG0360@2|Bacteria,2HPGC@201174|Actinobacteria,4CQUW@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S6	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158433_k127_243997_7	1380390.JIAT01000009_gene1856	3.47e-60	211.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158433_k127_243997_12	42256.RradSPS_0737	6.329e-15	84.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CQW6@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158433_k127_243997_9	469383.Cwoe_5913	6.359e-46	174.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CQHN@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158433_k127_243997_10	1122939.ATUD01000008_gene2354	4.247e-32	134.0	COG2898@1|root,COG2898@2|Bacteria,2I33N@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_243997_2	469383.Cwoe_5914	2.763e-144	471.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CPNU@84995|Rubrobacteria	84995|Rubrobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158433_k127_243997_8	1122939.ATUD01000006_gene1650	4.946e-50	185.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria,4CQKR@84995|Rubrobacteria	84995|Rubrobacteria	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158433_k127_2447573_24	1380390.JIAT01000009_gene2042	6.601e-13	74.0	2B9NP@1|root,32312@2|Bacteria,2HP6G@201174|Actinobacteria,4CQIB@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158433_k127_2447573_18	1380390.JIAT01000011_gene2661	2.138e-45	178.0	COG1051@1|root,COG1051@2|Bacteria,2HQ01@201174|Actinobacteria,4CRFN@84995|Rubrobacteria	84995|Rubrobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158433_k127_2447573_16	929712.KI912613_gene1795	6.222e-53	192.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CQJT@84995|Rubrobacteria	84995|Rubrobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158433_k127_2447573_23	469383.Cwoe_1559	3.172e-24	102.0	COG1773@1|root,COG1773@2|Bacteria,2GSAE@201174|Actinobacteria	201174|Actinobacteria	C	Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
SRR25158433_k127_2447573_0	469383.Cwoe_4226	2.363e-269	839.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4CRRH@84995|Rubrobacteria	84995|Rubrobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158433_k127_2447573_5	929712.KI912613_gene323	1.325e-97	328.0	COG0605@1|root,COG0605@2|Bacteria,2GJV8@201174|Actinobacteria,4CQ25@84995|Rubrobacteria	84995|Rubrobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158433_k127_2447573_13	1283299.AUKG01000002_gene3726	2.14e-63	229.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CSJY@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 3	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158433_k127_2447573_17	469383.Cwoe_4563	1.491e-46	184.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158433_k127_2447573_26	1380390.JIAT01000009_gene971	1.709e-11	69.0	COG1366@1|root,COG1366@2|Bacteria,2HRM9@201174|Actinobacteria,4CTP4@84995|Rubrobacteria	84995|Rubrobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158433_k127_2447573_25	1380390.JIAT01000015_gene5817	2.349e-12	75.0	2AWKA@1|root,31NH0@2|Bacteria,2HR28@201174|Actinobacteria,4CSX3@84995|Rubrobacteria	84995|Rubrobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158433_k127_2447573_14	1380390.JIAT01000009_gene2233	9.775e-60	224.0	COG0642@1|root,COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4CU1G@84995|Rubrobacteria	84995|Rubrobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS_9,SpoIIE
SRR25158433_k127_2447573_12	1123320.KB889664_gene1347	3.799e-70	250.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR25158433_k127_2447573_10	404589.Anae109_2572	9.379e-76	262.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria,2YZAW@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158433_k127_2447573_15	1380390.JIAT01000010_gene4864	1.732e-53	196.0	2DM23@1|root,31DUR@2|Bacteria,2GIYZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF2204,NTP_transf_5
SRR25158433_k127_2447573_28	1380390.JIAT01000009_gene562	9.041e-07	59.0	2AWFQ@1|root,31NBZ@2|Bacteria,2HQYB@201174|Actinobacteria,4CSQU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2447573_9	1380390.JIAT01000010_gene4865	3.921e-80	274.0	COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria	201174|Actinobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158433_k127_2447573_8	1283299.AUKG01000002_gene4555	2.016e-87	294.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158433_k127_2447573_2	479434.Sthe_0004	4.083e-129	419.0	COG2141@1|root,COG2141@2|Bacteria,2G5JS@200795|Chloroflexi,27XTW@189775|Thermomicrobia	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158433_k127_2447573_21	43354.JOIJ01000011_gene2698	3.428e-31	124.0	2DPE5@1|root,331QG@2|Bacteria,2IQE8@201174|Actinobacteria,4E5S3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2447573_27	1380347.JNII01000006_gene1332	4.079e-11	67.0	2DRBI@1|root,33B4D@2|Bacteria,2GWXK@201174|Actinobacteria,4ETJ0@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2447573_11	266117.Rxyl_1070	8.788e-72	248.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158433_k127_2447573_20	1380390.JIAT01000016_gene5568	2.866e-34	145.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CRKI@84995|Rubrobacteria	84995|Rubrobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158433_k127_2447573_19	102129.Lepto7375DRAFT_5970	1.56e-44	170.0	COG2320@1|root,COG2320@2|Bacteria,1G9KF@1117|Cyanobacteria	1117|Cyanobacteria	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
SRR25158433_k127_2447573_6	469383.Cwoe_4914	3.708e-95	325.0	COG1613@1|root,COG1613@2|Bacteria,2GJIK@201174|Actinobacteria,4CRE5@84995|Rubrobacteria	84995|Rubrobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SRR25158433_k127_2447573_7	1380390.JIAT01000009_gene1161	4.712e-91	308.0	COG0555@1|root,COG0555@2|Bacteria,2GP6P@201174|Actinobacteria,4CSDJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158433_k127_2447573_4	1283299.AUKG01000003_gene287	4.705e-98	331.0	COG4208@1|root,COG4208@2|Bacteria,2GMTK@201174|Actinobacteria,4CS5G@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158433_k127_2447573_3	469383.Cwoe_4911	6.449e-127	415.0	COG1118@1|root,COG1118@2|Bacteria,2I3KJ@201174|Actinobacteria,4CPG0@84995|Rubrobacteria	84995|Rubrobacteria	P	TOBE-like domain	-	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE,TOBE_3
SRR25158433_k127_2447573_1	251221.35214398	4.608e-181	583.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158433_k127_2447573_29	196627.cg0026	0.0001863	52.0	COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria,22KGY@1653|Corynebacteriaceae	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158433_k127_2457977_0	1123320.KB889585_gene1820	0.0	1008.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158433_k127_2457977_2	1122939.ATUD01000002_gene1184	4.269e-182	582.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CR5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158433_k127_2457977_7	1283299.AUKG01000001_gene2943	3.235e-58	208.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CQG1@84995|Rubrobacteria	84995|Rubrobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158433_k127_2457977_3	469383.Cwoe_1679	5.228e-117	386.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CPE8@84995|Rubrobacteria	84995|Rubrobacteria	J	Dihydrouridine synthase (Dus)	-	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158433_k127_2457977_4	469383.Cwoe_1678	3.996e-94	316.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CQ5C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158433_k127_2457977_9	1122939.ATUD01000002_gene1179	3.574e-47	180.0	COG0625@1|root,COG0625@2|Bacteria,2HQWF@201174|Actinobacteria,4CSPC@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158433_k127_2457977_6	469383.Cwoe_1676	2.415e-60	213.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4CQM0@84995|Rubrobacteria	84995|Rubrobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158433_k127_2457977_10	1380390.JIAT01000011_gene2843	2.323e-42	161.0	COG1539@1|root,COG1539@2|Bacteria,2HQ0Z@201174|Actinobacteria,4CRGX@84995|Rubrobacteria	84995|Rubrobacteria	H	Dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158433_k127_2457977_8	1121935.AQXX01000131_gene2792	2.028e-50	189.0	COG0824@1|root,COG0824@2|Bacteria,1R6A6@1224|Proteobacteria	1224|Proteobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2457977_5	469383.Cwoe_1674	2.049e-89	302.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CPWZ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158433_k127_2457977_1	1380390.JIAT01000011_gene2838	1.322e-185	585.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CPFJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158433_k127_2466660_0	469383.Cwoe_2426	9.003e-103	340.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158433_k127_2466660_2	935866.JAER01000012_gene3530	4.75e-76	270.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4DN8R@85009|Propionibacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158433_k127_2466660_1	68223.JNZY01000018_gene707	6.663e-95	319.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158433_k127_2466660_3	1464048.JNZS01000051_gene2371	7.004e-67	237.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4D8TN@85008|Micromonosporales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
SRR25158433_k127_2466660_4	1245471.PCA10_30450	1.795e-08	57.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,1RNJ9@1236|Gammaproteobacteria,1YFM2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158433_k127_2485725_7	469383.Cwoe_5281	2.197e-97	336.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4CPIR@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158433_k127_2485725_1	469383.Cwoe_0911	3.1e-234	743.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158433_k127_2485725_4	882083.SacmaDRAFT_2926	6.063e-154	492.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4DYMT@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158433_k127_2485725_21	469383.Cwoe_5279	3.188e-11	70.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_33
SRR25158433_k127_2485725_10	469383.Cwoe_5323	1.091e-69	242.0	COG3000@1|root,COG3000@2|Bacteria,2ISSM@201174|Actinobacteria,4CQ11@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158433_k127_2485725_20	1380390.JIAT01000009_gene781	1.049e-11	68.0	2AUW4@1|root,31KJJ@2|Bacteria,2HPE0@201174|Actinobacteria,4CQS2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2485725_13	1380390.JIAT01000009_gene776	1.439e-46	172.0	COG0071@1|root,COG0071@2|Bacteria,2HR04@201174|Actinobacteria,4CSTR@84995|Rubrobacteria	84995|Rubrobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158433_k127_2485725_0	1283299.AUKG01000003_gene544	0.0	1084.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPC3@84995|Rubrobacteria	84995|Rubrobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158433_k127_2485725_11	469383.Cwoe_5505	8.663e-63	240.0	COG5305@1|root,COG5305@2|Bacteria,2HPE5@201174|Actinobacteria,4CQS9@84995|Rubrobacteria	84995|Rubrobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158433_k127_2485725_16	1380390.JIAT01000009_gene773	1.11e-32	134.0	2AWFM@1|root,31NBV@2|Bacteria,2HQY5@201174|Actinobacteria,4CSQN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2485725_12	1283299.AUKG01000003_gene546	4.027e-56	202.0	COG1309@1|root,COG1309@2|Bacteria,2HQ9V@201174|Actinobacteria,4CRTR@84995|Rubrobacteria	84995|Rubrobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158433_k127_2485725_2	469383.Cwoe_1195	3.856e-198	641.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_2485725_5	487521.OCU_15590	3.954e-125	415.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,2369H@1762|Mycobacteriaceae	201174|Actinobacteria	J	Belongs to the amidase family	amiB2	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158433_k127_2485725_6	469383.Cwoe_5269	2.05e-118	395.0	COG0208@1|root,COG3255@1|root,COG0208@2|Bacteria,COG3255@2|Bacteria,2GK48@201174|Actinobacteria,4CR5N@84995|Rubrobacteria	84995|Rubrobacteria	FI	Ribonucleotide reductase, small chain	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_sm,SCP2
SRR25158433_k127_2485725_9	469383.Cwoe_3906	5.102e-84	284.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lpsA1	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2,PGAP1
SRR25158433_k127_2485725_3	457429.ABJI02000040_gene3859	5.397e-198	628.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158433_k127_2485725_8	469383.Cwoe_5573	8.246e-94	316.0	COG0385@1|root,COG0385@2|Bacteria,2GMAM@201174|Actinobacteria,4CTGU@84995|Rubrobacteria	84995|Rubrobacteria	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
SRR25158433_k127_2485725_15	1074488.AGBX01000007_gene1580	2.295e-42	162.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4FCU7@85020|Dermabacteraceae	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158433_k127_2485725_17	1440053.JOEI01000027_gene2996	7.187e-26	112.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158433_k127_2485725_19	1312959.KI914656_gene798	4.994e-21	104.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,1W98Z@1268|Micrococcaceae	201174|Actinobacteria	O	peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158433_k127_2485725_18	1120949.KB903315_gene213	5.451e-25	111.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4DDWS@85008|Micromonosporales	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158433_k127_2485725_14	710111.FraQA3DRAFT_3377	2.735e-44	169.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4EVS8@85013|Frankiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158433_k127_2507379_3	1380390.JIAT01000009_gene362	4.405e-112	369.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158433_k127_2507379_4	1122939.ATUD01000007_gene2114	1.383e-96	331.0	COG1708@1|root,COG1708@2|Bacteria,2H951@201174|Actinobacteria,4CP65@84995|Rubrobacteria	84995|Rubrobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2507379_6	1283299.AUKG01000002_gene5090	6.772e-78	267.0	COG1082@1|root,COG1082@2|Bacteria,2HNRF@201174|Actinobacteria,4CPYX@84995|Rubrobacteria	84995|Rubrobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158433_k127_2507379_14	1304874.JAFY01000001_gene2618	0.0001773	53.0	COG2856@1|root,COG2856@2|Bacteria,3TBV1@508458|Synergistetes	508458|Synergistetes	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158433_k127_2507379_11	292459.STH1116	2.488e-43	179.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,24DGJ@186801|Clostridia	186801|Clostridia	S	SMART metal-dependent phosphohydrolase, HD	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158433_k127_2507379_0	266117.Rxyl_0469	2.157e-219	686.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CPC6@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158433_k127_2507379_9	1122939.ATUD01000001_gene328	9.287e-52	194.0	2EN03@1|root,33FN9@2|Bacteria,2HNYF@201174|Actinobacteria,4CQ7V@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
SRR25158433_k127_2507379_12	1283299.AUKG01000002_gene3863	3.115e-39	158.0	COG0009@1|root,COG0009@2|Bacteria,2HPE4@201174|Actinobacteria,4CQS7@84995|Rubrobacteria	84995|Rubrobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158433_k127_2507379_8	469383.Cwoe_4634	1.54e-54	203.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158433_k127_2507379_2	266117.Rxyl_1652	1.603e-124	409.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CP8A@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158433_k127_2507379_1	1380390.JIAT01000009_gene371	2.693e-134	435.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158433_k127_2507379_13	525909.Afer_1810	1.431e-29	119.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CP0K@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158433_k127_2507379_5	1380390.JIAT01000017_gene5272	3.174e-81	289.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CU6W@84995|Rubrobacteria	84995|Rubrobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
SRR25158433_k127_2507379_7	1380390.JIAT01000011_gene2847	1.965e-62	221.0	COG1309@1|root,COG1309@2|Bacteria,2GNR9@201174|Actinobacteria,4CQDU@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_2507379_10	1380390.JIAT01000011_gene2848	4.817e-49	180.0	COG2267@1|root,COG2267@2|Bacteria,2HJ2M@201174|Actinobacteria,4CRFH@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158433_k127_250844_0	585531.HMPREF0063_11548	2.086e-134	455.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DNJP@85009|Propionibacteriales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_250844_1	1089545.KB913037_gene2155	2.526e-39	155.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4EB77@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
SRR25158433_k127_2512330_14	573370.DMR_03420	2.408e-36	138.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,42S33@68525|delta/epsilon subdivisions,2WNKG@28221|Deltaproteobacteria,2MC3F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2512330_18	638302.HMPREF0908_0610	2.038e-12	68.0	2EU6P@1|root,33MP7@2|Bacteria,1VM14@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2512330_11	1463934.JOCF01000022_gene6284	4.791e-62	225.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	todF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158433_k127_2512330_13	570268.ANBB01000027_gene693	1.777e-56	210.0	COG0596@1|root,COG0596@2|Bacteria,2I2VI@201174|Actinobacteria,4EHCZ@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158433_k127_2512330_0	469383.Cwoe_3534	4.368e-185	588.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158433_k127_2512330_2	469383.Cwoe_3533	1.281e-100	338.0	COG3705@1|root,COG3705@2|Bacteria,2I6IJ@201174|Actinobacteria,4CQ6U@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidyl-tRNA synthetase	-	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR25158433_k127_2512330_4	1283299.AUKG01000002_gene4907	7.448e-75	264.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CPQH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
SRR25158433_k127_2512330_3	867903.ThesuDRAFT_01961	5.669e-80	291.0	COG0079@1|root,COG0141@1|root,COG0079@2|Bacteria,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3WCUR@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_1_2,Histidinol_dh
SRR25158433_k127_2512330_5	1380390.JIAT01000010_gene4517	1.659e-74	266.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CPW7@84995|Rubrobacteria	84995|Rubrobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158433_k127_2512330_6	469383.Cwoe_3529	3.299e-71	252.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CQ9Q@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158433_k127_2512330_8	469383.Cwoe_3528	5.237e-65	233.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CPKT@84995|Rubrobacteria	84995|Rubrobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158433_k127_2512330_1	429009.Adeg_0317	9.174e-103	339.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,42FAR@68295|Thermoanaerobacterales	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05755	His_biosynth
SRR25158433_k127_2512330_12	929712.KI912613_gene3921	4.553e-60	223.0	COG0617@1|root,COG0617@2|Bacteria,2HPJN@201174|Actinobacteria,4CQXB@84995|Rubrobacteria	84995|Rubrobacteria	J	Poly A polymerase head domain	-	-	-	-	-	-	-	-	-	-	-	-	PolyA_pol
SRR25158433_k127_2512330_9	469383.Cwoe_3524	1.231e-64	230.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CQFG@84995|Rubrobacteria	84995|Rubrobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158433_k127_2512330_7	469383.Cwoe_3523	1.55e-67	248.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CQAV@84995|Rubrobacteria	84995|Rubrobacteria	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158433_k127_2512330_10	469383.Cwoe_3522	1.363e-64	226.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158433_k127_2512330_16	269800.Tfu_2708	1.097e-26	121.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4EHTN@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158433_k127_2512330_17	1283299.AUKG01000002_gene4921	1.529e-16	83.0	COG0762@1|root,COG0762@2|Bacteria,2HR5Q@201174|Actinobacteria,4CT15@84995|Rubrobacteria	84995|Rubrobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158433_k127_2512330_15	469383.Cwoe_3519	1.558e-30	130.0	COG0597@1|root,COG0597@2|Bacteria,2HP4E@201174|Actinobacteria,4CQFY@84995|Rubrobacteria	84995|Rubrobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158433_k127_2512330_19	357808.RoseRS_2986	9.84e-09	70.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
SRR25158433_k127_2520941_3	479433.Caci_8845	3.539e-15	82.0	COG3757@1|root,COG3757@2|Bacteria,2I2YG@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
SRR25158433_k127_2520941_4	929712.KI912613_gene961	0.0001181	52.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,DUF320
SRR25158433_k127_2520941_0	383372.Rcas_1653	2.588e-166	551.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158433_k127_2520941_1	1380390.JIAT01000011_gene2653	1.562e-61	228.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4CQ8G@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_2520941_2	469383.Cwoe_5785	2.993e-57	203.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4CPJ7@84995|Rubrobacteria	84995|Rubrobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158433_k127_2539495_2	1380390.JIAT01000009_gene522	2.166e-277	864.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158433_k127_2539495_21	469383.Cwoe_3948	2.631e-27	111.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4CQPR@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158433_k127_2539495_14	118168.MC7420_2493	6.887e-57	225.0	COG1404@1|root,COG2931@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
SRR25158433_k127_2539495_7	1122939.ATUD01000001_gene295	1.414e-129	452.0	COG1404@1|root,COG1404@2|Bacteria,2IA44@201174|Actinobacteria	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,P_proprotein,Peptidase_S8
SRR25158433_k127_2539495_9	1380390.JIAT01000016_gene5523	1.153e-96	323.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria	201174|Actinobacteria	V	abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158433_k127_2539495_12	1380390.JIAT01000016_gene5524	6.107e-66	248.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria	201174|Actinobacteria	S	Involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158433_k127_2539495_8	1278073.MYSTI_05949	6.499e-129	422.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,42NPS@68525|delta/epsilon subdivisions,2WWDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
SRR25158433_k127_2539495_15	1429916.X566_09540	1.13e-47	181.0	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,2UA6G@28211|Alphaproteobacteria,3K0B6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
SRR25158433_k127_2539495_18	1380390.JIAT01000003_gene5418	5.705e-41	176.0	COG0398@1|root,COG0398@2|Bacteria,2HP5Q@201174|Actinobacteria,4CQHS@84995|Rubrobacteria	84995|Rubrobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158433_k127_2539495_4	469383.Cwoe_5408	8.51e-154	510.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CP74@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix containing domain	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158433_k127_2539495_13	164757.Mjls_5558	7.814e-61	217.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria,233SA@1762|Mycobacteriaceae	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158433_k127_2539495_20	981369.JQMJ01000004_gene2163	6.103e-39	150.0	2E4BX@1|root,32Z7H@2|Bacteria,2IM6W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR25158433_k127_2539495_11	1283299.AUKG01000002_gene3872	9.699e-71	255.0	COG0208@1|root,COG0208@2|Bacteria,2GK48@201174|Actinobacteria,4CRR0@84995|Rubrobacteria	84995|Rubrobacteria	F	Ribonucleotide reductase, small chain	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_sm
SRR25158433_k127_2539495_23	469383.Cwoe_2923	4e-17	84.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2539495_29	1283299.AUKG01000003_gene503	0.0002902	51.0	COG0662@1|root,COG0662@2|Bacteria,2HR3M@201174|Actinobacteria,4CSZ1@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_2539495_17	290397.Adeh_3099	1.231e-42	164.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,42T50@68525|delta/epsilon subdivisions,2WPVV@28221|Deltaproteobacteria,2YUY1@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158433_k127_2539495_22	419947.MRA_1447	9.735e-21	98.0	COG3631@1|root,COG3631@2|Bacteria,2GUSJ@201174|Actinobacteria,23C5Y@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158433_k127_2539495_26	1267534.KB906754_gene3349	1.512e-10	68.0	COG2329@1|root,COG5485@1|root,COG2329@2|Bacteria,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158433_k127_2539495_16	1380390.JIAT01000010_gene4679	1.526e-45	171.0	COG1670@1|root,COG1670@2|Bacteria,2IFMK@201174|Actinobacteria,4CQJ1@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_3
SRR25158433_k127_2539495_6	469383.Cwoe_3628	1.774e-132	436.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4CRC9@84995|Rubrobacteria	84995|Rubrobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158433_k127_2539495_24	500153.JOEK01000003_gene1080	8.995e-16	89.0	2DUW4@1|root,32UXY@2|Bacteria,2IJWI@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158433_k127_2539495_5	469383.Cwoe_3745	5.451e-147	472.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CQ1M@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158433_k127_2539495_3	469383.Cwoe_0846	3.292e-190	605.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CR3U@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158433_k127_2539495_19	251221.35213566	1.312e-40	173.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2539495_25	7739.XP_002599256.1	2.621e-14	87.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa	33208|Metazoa	T	lipoprotein receptor-related protein	-	-	-	ko:K03068,ko:K20051	ko04150,ko04310,ko05200,ko05224,ko05225,ko05226,map04150,map04310,map05200,map05224,map05225,map05226	-	-	-	ko00000,ko00001,ko04131	-	-	-	Ephrin_rec_like,FXa_inhibition,Ldl_recept_a,Ldl_recept_b
SRR25158433_k127_2539495_0	469383.Cwoe_1618	0.0	1045.0	COG3968@1|root,COG3968@2|Bacteria,2GMA9@201174|Actinobacteria,4CS2J@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutamine synthetase type III N terminal	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158433_k127_2539495_28	1380390.JIAT01000014_gene6234	3.529e-06	51.0	COG0791@1|root,COG0791@2|Bacteria,2HQTI@201174|Actinobacteria,4CSIU@84995|Rubrobacteria	84995|Rubrobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2539495_1	1380390.JIAT01000011_gene2819	2.724e-292	911.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,4CPBM@84995|Rubrobacteria	84995|Rubrobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158433_k127_2539495_27	1380390.JIAT01000011_gene2820	8.974e-07	54.0	COG0846@1|root,COG0846@2|Bacteria,2IFPA@201174|Actinobacteria,4CQ9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158433_k127_2545062_6	469383.Cwoe_5791	5.067e-98	326.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158433_k127_2545062_16	469383.Cwoe_3654	2.564e-09	66.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HTH_20,HTH_5
SRR25158433_k127_2545062_10	1283299.AUKG01000002_gene4560	1.106e-69	251.0	COG0476@1|root,COG0476@2|Bacteria,2HGW4@201174|Actinobacteria	201174|Actinobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158433_k127_2545062_9	349741.Amuc_0062	2.535e-71	249.0	2CJNI@1|root,2Z7QY@2|Bacteria	2|Bacteria	L	Type II restriction endonuclease, EcoRI family protein	ecoRIR	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoRI
SRR25158433_k127_2545062_1	1108045.GORHZ_055_00260	1.764e-138	451.0	COG3392@1|root,COG3392@2|Bacteria,2IBCB@201174|Actinobacteria	201174|Actinobacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
SRR25158433_k127_2545062_17	84531.JMTZ01000027_gene2	2.158e-05	55.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1X58E@135614|Xanthomonadales	135614|Xanthomonadales	Q	ORF located using	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
SRR25158433_k127_2545062_5	469383.Cwoe_2075	8.384e-123	400.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4CPIH@84995|Rubrobacteria	84995|Rubrobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158433_k127_2545062_18	40571.JOEA01000018_gene8023	0.0002346	53.0	COG1158@1|root,COG1158@2|Bacteria,2IKUK@201174|Actinobacteria,4E5YF@85010|Pseudonocardiales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2545062_14	1283299.AUKG01000003_gene572	1.517e-15	79.0	2E5JX@1|root,330B5@2|Bacteria,2HREB@201174|Actinobacteria,4CTCI@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
SRR25158433_k127_2545062_13	1129374.AJE_07805	5.488e-19	89.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,468AF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
SRR25158433_k127_2545062_15	573370.DMR_14340	4.746e-11	66.0	29XTP@1|root,30JJR@2|Bacteria,1QTBX@1224|Proteobacteria,436Y4@68525|delta/epsilon subdivisions,2X1NB@28221|Deltaproteobacteria,2MFCX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SRR25158433_k127_2545062_8	1380390.JIAT01000010_gene4131	2.961e-86	299.0	COG0477@1|root,COG2814@2|Bacteria,2HQMP@201174|Actinobacteria,4CS79@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_2545062_4	1122939.ATUD01000005_gene2570	1.623e-128	440.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4CRUH@84995|Rubrobacteria	84995|Rubrobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158433_k127_2545062_2	471852.Tcur_3855	4.227e-138	451.0	COG3616@1|root,COG3616@2|Bacteria,2GJMB@201174|Actinobacteria,4EGAN@85012|Streptosporangiales	201174|Actinobacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
SRR25158433_k127_2545062_11	68170.KL590530_gene11452	1.635e-42	165.0	2DI0V@1|root,301MZ@2|Bacteria,2H2A6@201174|Actinobacteria,4E9XX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2545062_0	1380390.JIAT01000010_gene4676	1.162e-220	699.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CS2V@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158433_k127_2545062_3	469383.Cwoe_1054	1.004e-130	443.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CPJ2@84995|Rubrobacteria	84995|Rubrobacteria	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158433_k127_2545062_7	1122939.ATUD01000001_gene50	5.687e-91	315.0	COG1024@1|root,COG1024@2|Bacteria,2I9BK@201174|Actinobacteria,4CPE3@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158433_k127_2545062_12	685035.ADAE01000002_gene2523	1.082e-35	143.0	COG2050@1|root,COG2050@2|Bacteria,1N4SW@1224|Proteobacteria,2UD9E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
SRR25158433_k127_2550991_10	489825.LYNGBM3L_21190	3.136e-25	106.0	COG0438@1|root,COG0438@2|Bacteria,1GC2Y@1117|Cyanobacteria	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2550991_6	1380394.JADL01000003_gene5156	8.168e-63	233.0	COG0438@1|root,COG0438@2|Bacteria,1RAGT@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2550991_1	1121440.AUMA01000016_gene161	9.426e-150	496.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158433_k127_2550991_9	469383.Cwoe_4191	2.04e-39	149.0	COG2127@1|root,COG2127@2|Bacteria,2HPG0@201174|Actinobacteria,4CQUJ@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158433_k127_2550991_0	469383.Cwoe_4193	9.193e-318	985.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4CPAH@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158433_k127_2550991_4	469383.Cwoe_4205	7.235e-77	286.0	2AV8W@1|root,31KZS@2|Bacteria,2HPQ4@201174|Actinobacteria,4CR2W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2550991_2	469383.Cwoe_5296	7.149e-136	449.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CRCH@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158433_k127_2550991_5	469383.Cwoe_5304	1.697e-73	267.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CQDP@84995|Rubrobacteria	84995|Rubrobacteria	D	biosynthesis protein	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,Wzz
SRR25158433_k127_2550991_11	1173025.GEI7407_2192	1.941e-17	96.0	28IP7@1|root,2Z8P8@2|Bacteria,1G122@1117|Cyanobacteria,1H9WF@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158433_k127_2550991_8	1120972.AUMH01000005_gene890	3.805e-46	190.0	COG0438@1|root,COG0438@2|Bacteria,1TR6R@1239|Firmicutes,4HEIZ@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158433_k127_2550991_7	649831.L083_7327	3.636e-49	194.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DB93@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158433_k127_2550991_3	1380390.JIAT01000009_gene364	4.65e-125	422.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158433_k127_2550991_12	1283299.AUKG01000001_gene1903	1.612e-06	50.0	COG0438@1|root,COG0438@2|Bacteria,2GJI0@201174|Actinobacteria,4CQWI@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158433_k127_2593916_2	469383.Cwoe_1666	6.651e-124	419.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
SRR25158433_k127_2593916_7	38727.Pavir.Da02069.1.p	0.0004131	46.0	COG0642@1|root,KOG0519@2759|Eukaryota,37KWP@33090|Viridiplantae,3GB9R@35493|Streptophyta,3KY1W@4447|Liliopsida,3I5KR@38820|Poales	35493|Streptophyta	T	His Kinase A (phosphoacceptor) domain	-	GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005911,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007275,GO:0008150,GO:0008152,GO:0009506,GO:0009553,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009755,GO:0009888,GO:0009987,GO:0010033,GO:0010087,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023052,GO:0030054,GO:0032501,GO:0032502,GO:0032870,GO:0036211,GO:0040007,GO:0042221,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046983,GO:0048229,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055044,GO:0065007,GO:0070887,GO:0071310,GO:0071368,GO:0071495,GO:0071704,GO:0071944,GO:0080117,GO:0080190,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158433_k127_2593916_6	1380390.JIAT01000011_gene2830	1.598e-13	76.0	2904D@1|root,2ZMUB@2|Bacteria,2H0MU@201174|Actinobacteria,4CSUN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2593916_5	929712.KI912613_gene4807	5.042e-34	143.0	COG2820@1|root,COG2820@2|Bacteria,2I4KP@201174|Actinobacteria,4CQU2@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158433_k127_2593916_0	469383.Cwoe_1639	1.501e-158	516.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CP60@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158433_k127_2593916_4	469383.Cwoe_1640	4.52e-47	172.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4CQ3C@84995|Rubrobacteria	84995|Rubrobacteria	E	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158433_k127_2593916_1	469383.Cwoe_1670	8.35e-125	411.0	COG0789@1|root,COG2114@1|root,COG0789@2|Bacteria,COG2114@2|Bacteria,2ICT6@201174|Actinobacteria,4CR4V@84995|Rubrobacteria	84995|Rubrobacteria	KT	Adenylate cyclase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	Ad_Cy_reg,Guanylate_cyc,MerR_1
SRR25158433_k127_2593916_3	469383.Cwoe_1671	5.726e-95	317.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CQ9P@84995|Rubrobacteria	84995|Rubrobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
SRR25158433_k127_2598919_2	469383.Cwoe_1389	9.51e-12	68.0	2AXD0@1|root,31PCB@2|Bacteria,2HRSN@201174|Actinobacteria,4CTVR@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2598919_0	469383.Cwoe_1388	8.963e-207	659.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CPFF@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158433_k127_2598919_1	1380390.JIAT01000011_gene2626	2.156e-158	509.0	COG1752@1|root,COG1752@2|Bacteria,2HPRW@201174|Actinobacteria,4CR58@84995|Rubrobacteria	84995|Rubrobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158433_k127_2598919_3	765912.Thimo_0006	5.712e-09	57.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales	135613|Chromatiales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SRR25158433_k127_260390_7	929712.KI912613_gene2430	3.642e-87	291.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CP64@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158433_k127_260390_11	1283299.AUKG01000003_gene301	2.339e-51	197.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CP9Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158433_k127_260390_2	1380390.JIAT01000009_gene1148	1.704e-178	573.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4CR2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158433_k127_260390_0	469383.Cwoe_1155	7.341e-270	855.0	COG1034@1|root,COG1153@1|root,COG1034@2|Bacteria,COG1153@2|Bacteria,2GJGX@201174|Actinobacteria,4CR3F@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158433_k127_260390_4	1283299.AUKG01000003_gene298	3.256e-119	391.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CQ5K@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158433_k127_260390_5	469383.Cwoe_1157	7.21e-94	311.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CQRQ@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158433_k127_260390_14	1283299.AUKG01000004_gene1085	1.124e-35	141.0	arCOG11477@1|root,32TJG@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158433_k127_260390_12	469383.Cwoe_1158	1.456e-42	167.0	COG0839@1|root,COG0839@2|Bacteria,2HRQ0@201174|Actinobacteria,4CTSA@84995|Rubrobacteria	84995|Rubrobacteria	C	plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158433_k127_260390_13	1283299.AUKG01000003_gene295	5.026e-39	147.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CQIE@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158433_k127_260390_1	1283299.AUKG01000003_gene294	1.167e-224	714.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CPCM@84995|Rubrobacteria	84995|Rubrobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158433_k127_260390_3	1283299.AUKG01000003_gene293	7.058e-153	508.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CQ12@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158433_k127_260390_8	469383.Cwoe_1162	3.523e-68	246.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CPJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158433_k127_260390_6	469383.Cwoe_1162	1.896e-89	301.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CPJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158433_k127_260390_9	1380390.JIAT01000009_gene1891	7.982e-65	234.0	COG0679@1|root,COG0679@2|Bacteria,2H13X@201174|Actinobacteria,4CQBH@84995|Rubrobacteria	84995|Rubrobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158433_k127_260390_16	1380390.JIAT01000009_gene2141	1.033e-20	96.0	2AWXB@1|root,31NUY@2|Bacteria,2HRCQ@201174|Actinobacteria,4CTA9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_260390_10	197221.22294879	2.4e-60	220.0	COG1351@1|root,COG1351@2|Bacteria,1GDYD@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158433_k127_260390_17	1283299.AUKG01000003_gene260	7.288e-09	66.0	2AUIS@1|root,31K7B@2|Bacteria,2HP5N@201174|Actinobacteria,4CQHP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_260390_15	1121423.JONT01000012_gene439	3.691e-22	106.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,25ESC@186801|Clostridia,267BX@186807|Peptococcaceae	186801|Clostridia	S	pfam cbs	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158433_k127_2617337_1	1283299.AUKG01000003_gene204	4.506e-110	360.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158433_k127_2617337_5	469383.Cwoe_3112	1.435e-12	77.0	2E3FZ@1|root,32YET@2|Bacteria,2IGAC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2617337_3	580327.Tthe_2568	1.351e-62	226.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,42G1D@68295|Thermoanaerobacterales	186801|Clostridia	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158433_k127_2617337_0	1283299.AUKG01000001_gene1277	4.127e-196	626.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4CRF1@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158433_k127_2617337_2	469383.Cwoe_4550	1.672e-105	348.0	COG0300@1|root,COG3320@1|root,COG0300@2|Bacteria,COG3320@2|Bacteria,2GJ1R@201174|Actinobacteria,4CR82@84995|Rubrobacteria	84995|Rubrobacteria	Q	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
SRR25158433_k127_2684656_5	1380390.JIAT01000010_gene4238	9.129e-93	329.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,4CPC4@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158433_k127_2684656_7	1122939.ATUD01000002_gene1192	1.067e-45	174.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4CQHT@84995|Rubrobacteria	84995|Rubrobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158433_k127_2684656_3	469383.Cwoe_1689	6.118e-107	374.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CQ7N@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR25158433_k127_2684656_4	469383.Cwoe_5385	4.312e-97	327.0	COG1808@1|root,COG1808@2|Bacteria,2GJQ4@201174|Actinobacteria,4CRP3@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158433_k127_2684656_9	1283299.AUKG01000002_gene4357	0.0008535	47.0	2AXJJ@1|root,31PJM@2|Bacteria,2HRXU@201174|Actinobacteria,4CU14@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2684656_8	469383.Cwoe_1688	7.04e-44	173.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CQE7@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158433_k127_2684656_6	1380390.JIAT01000011_gene2866	6.461e-76	259.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CPVJ@84995|Rubrobacteria	84995|Rubrobacteria	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158433_k127_2684656_0	469383.Cwoe_1686	2.766e-172	546.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4CPEN@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA integrity scanning protein DisA	-	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH_2
SRR25158433_k127_2684656_1	469383.Cwoe_1556	3.249e-170	541.0	COG0667@1|root,COG0667@2|Bacteria,2HQ4U@201174|Actinobacteria,4CRMQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158433_k127_2684656_2	1408254.T458_25050	3.683e-141	457.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,26RRK@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158433_k127_2686348_9	469383.Cwoe_3799	6.95e-98	335.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158433_k127_2686348_24	1283299.AUKG01000002_gene4572	1.502e-37	160.0	COG0619@1|root,COG0619@2|Bacteria,2IIUE@201174|Actinobacteria,4CRAP@84995|Rubrobacteria	84995|Rubrobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158433_k127_2686348_17	1380390.JIAT01000010_gene4104	1.92e-66	238.0	28RTZ@1|root,2ZE6B@2|Bacteria,2HQNJ@201174|Actinobacteria,4CS8Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
SRR25158433_k127_2686348_31	469371.Tbis_1038	4.034e-29	128.0	COG3591@1|root,COG3591@2|Bacteria,2GJVS@201174|Actinobacteria,4DX5J@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158433_k127_2686348_34	1380390.JIAT01000010_gene4844	1.782e-24	106.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria,4CSUA@84995|Rubrobacteria	84995|Rubrobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2686348_33	1380390.JIAT01000010_gene4090	1.267e-24	112.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158433_k127_2686348_47	1380390.JIAT01000010_gene4090	1.554e-05	54.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158433_k127_2686348_13	469383.Cwoe_1004	1.094e-79	287.0	COG0018@1|root,COG0018@2|Bacteria	2|Bacteria	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158433_k127_2686348_3	543632.JOJL01000013_gene9338	1.37e-204	662.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,2GKJT@201174|Actinobacteria,4D9MP@85008|Micromonosporales	201174|Actinobacteria	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
SRR25158433_k127_2686348_39	272123.Anacy_3718	5.304e-18	100.0	COG0115@1|root,COG1247@1|root,COG0115@2|Bacteria,COG1247@2|Bacteria,1G1GM@1117|Cyanobacteria,1HT7W@1161|Nostocales	1117|Cyanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158433_k127_2686348_21	272123.Anacy_3717	3.923e-57	217.0	COG0123@1|root,COG0123@2|Bacteria	2|Bacteria	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
SRR25158433_k127_2686348_38	103733.JNYO01000022_gene6934	2.035e-18	88.0	COG1605@1|root,COG1605@2|Bacteria,2ISDT@201174|Actinobacteria,4EDBV@85010|Pseudonocardiales	201174|Actinobacteria	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
SRR25158433_k127_2686348_6	1068980.ARVW01000001_gene1524	1.316e-124	419.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4E0VF@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158433_k127_2686348_19	1287475.HMPREF1650_09615	1.141e-58	231.0	COG3486@1|root,COG3486@2|Bacteria,2I991@201174|Actinobacteria,22M8M@1653|Corynebacteriaceae	201174|Actinobacteria	Q	L-lysine 6-monooxygenase (NADPH-requiring)	mbtG	GO:0003674,GO:0003824,GO:0004497,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009237,GO:0009712,GO:0009987,GO:0016491,GO:0016701,GO:0016703,GO:0016705,GO:0016709,GO:0018958,GO:0019184,GO:0019290,GO:0019540,GO:0019748,GO:0034641,GO:0040007,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044550,GO:0047091,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901615	-	ko:K04793	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	K_oxygenase
SRR25158433_k127_2686348_4	469383.Cwoe_1286	4.678e-161	522.0	COG1520@1|root,COG4993@1|root,COG1520@2|Bacteria,COG4993@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
SRR25158433_k127_2686348_29	1235457.C404_23430	4.612e-30	138.0	COG1232@1|root,COG1232@2|Bacteria,1NJ9K@1224|Proteobacteria,2VXAI@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158433_k127_2686348_42	877455.Metbo_1685	1.662e-09	71.0	COG0382@1|root,arCOG00476@2157|Archaea,2XWP0@28890|Euryarchaeota	28890|Euryarchaeota	H	UbiA prenyltransferase family	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
SRR25158433_k127_2686348_27	765420.OSCT_0650	6.106e-33	141.0	2DWHV@1|root,340DF@2|Bacteria	2|Bacteria	M	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158433_k127_2686348_20	285514.JNWO01000043_gene407	2.584e-58	231.0	COG4995@1|root,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Peptidase_C14,TIR_2
SRR25158433_k127_2686348_35	1906.SFRA_29915	1.184e-22	104.0	2FCM7@1|root,344QG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2686348_44	1296990.H845_747	1.34e-06	57.0	2BD51@1|root,32TR2@2|Bacteria,1N4UA@1224|Proteobacteria,2UEW3@28211|Alphaproteobacteria,2JX0Z@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2686348_37	1268303.RHODMAR_4989	2.247e-22	105.0	2EUVM@1|root,30HSY@2|Bacteria,2H98S@201174|Actinobacteria,4G1ZU@85025|Nocardiaceae	201174|Actinobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158433_k127_2686348_45	1411123.JQNH01000001_gene855	2.082e-06	56.0	COG1708@1|root,COG1708@2|Bacteria,1PXTE@1224|Proteobacteria,2UKXP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158433_k127_2686348_43	880072.Desac_0557	2.191e-07	57.0	COG1895@1|root,COG1895@2|Bacteria,1Q7Y6@1224|Proteobacteria,433AB@68525|delta/epsilon subdivisions,2WYB2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SRR25158433_k127_2686348_48	1160718.SU9_28826	0.0009359	48.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158433_k127_2686348_10	1380356.JNIK01000016_gene3679	5.016e-90	305.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria,4ESFU@85013|Frankiales	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158433_k127_2686348_12	469383.Cwoe_1838	2.54e-80	280.0	COG0420@1|root,COG0420@2|Bacteria,2HPX3@201174|Actinobacteria,4CRBR@84995|Rubrobacteria	84995|Rubrobacteria	L	3'-5' exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158433_k127_2686348_7	469383.Cwoe_0102	5.214e-121	409.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4CU6B@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158433_k127_2686348_30	1122611.KB903987_gene3980	5.26e-30	131.0	COG3591@1|root,COG3591@2|Bacteria,2GJVS@201174|Actinobacteria,4EGSC@85012|Streptosporangiales	201174|Actinobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2686348_22	1283299.AUKG01000001_gene2476	8.372e-44	169.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2686348_41	1283299.AUKG01000005_gene8	8.176e-14	85.0	COG1714@1|root,COG1714@2|Bacteria,2HRTA@201174|Actinobacteria,4CTWR@84995|Rubrobacteria	84995|Rubrobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158433_k127_2686348_26	1122939.ATUD01000001_gene115	4.646e-33	133.0	COG1917@1|root,COG1917@2|Bacteria,2HN4T@201174|Actinobacteria,4CQJ2@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2686348_18	1449353.JQMQ01000005_gene5697	4.253e-62	221.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria	201174|Actinobacteria	L	Pfam NUDIX	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158433_k127_2686348_36	1172188.KB911824_gene3347	1.678e-22	104.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria,4FK1U@85021|Intrasporangiaceae	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SRR25158433_k127_2686348_23	644548.SCNU_13854	4.194e-40	159.0	COG3945@1|root,COG3945@2|Bacteria,2IA3E@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158433_k127_2686348_14	563192.HMPREF0179_02682	1.78e-77	280.0	COG1700@1|root,COG1700@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09124,ko:K17440	-	-	-	-	br01610,ko00000,ko03011	-	-	-	DUF2357,PDDEXK_7
SRR25158433_k127_2686348_8	331869.BAL199_30665	1.748e-98	350.0	COG1401@1|root,COG1401@2|Bacteria,1NX8Q@1224|Proteobacteria,2U0YU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	GTPase subunit of restriction	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158433_k127_2686348_40	1158606.I579_01762	1.558e-17	98.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,4B3D4@81852|Enterococcaceae	91061|Bacilli	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158433_k127_2686348_16	469383.Cwoe_3526	6.287e-73	261.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158433_k127_2686348_5	469383.Cwoe_0401	1.307e-149	487.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158433_k127_2686348_1	469383.Cwoe_2712	2.492e-263	818.0	COG4799@1|root,COG4799@2|Bacteria,2I46V@201174|Actinobacteria,4CRHW@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158433_k127_2686348_25	469383.Cwoe_0938	5.289e-35	146.0	COG3832@1|root,COG3832@2|Bacteria,2IKZ7@201174|Actinobacteria	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158433_k127_2686348_11	1122604.JONR01000007_gene2832	6.623e-89	301.0	COG0491@1|root,COG0491@2|Bacteria,1N1ZW@1224|Proteobacteria,1RNRE@1236|Gammaproteobacteria,1X4Z9@135614|Xanthomonadales	135614|Xanthomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_2686348_0	469383.Cwoe_4482	5.278e-309	973.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4CPI8@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158433_k127_2686348_15	1463920.JOGB01000053_gene5026	4.016e-74	281.0	COG0596@1|root,COG0596@2|Bacteria,2I1Q9@201174|Actinobacteria	201174|Actinobacteria	EGP	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158433_k127_2686348_2	211114.JOEF01000001_gene7443	2.236e-216	682.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZT6@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158433_k127_2686348_28	1212548.B381_13223	8.672e-32	129.0	COG0446@1|root,COG0446@2|Bacteria,1QU0H@1224|Proteobacteria,1S8PV@1236|Gammaproteobacteria,1Z2TJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158433_k127_2703479_0	1463825.JNXC01000050_gene7411	0.0	1543.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4E234@85010|Pseudonocardiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	ko:K12436	-	-	-	-	ko00000,ko01004	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158433_k127_2751667_0	1122939.ATUD01000009_gene3023	5.655e-271	848.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158433_k127_2751667_18	1123371.ATXH01000003_gene1945	4.403e-05	57.0	COG0760@1|root,COG0760@2|Bacteria,2GHMC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
SRR25158433_k127_2751667_2	498761.HM1_1316	6.84e-178	566.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158433_k127_2751667_15	469383.Cwoe_5237	8.998e-11	67.0	COG2919@1|root,COG2919@2|Bacteria,2HRVE@201174|Actinobacteria,4CTYU@84995|Rubrobacteria	84995|Rubrobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158433_k127_2751667_14	1380390.JIAT01000009_gene716	1.709e-15	88.0	2AUU5@1|root,31KH9@2|Bacteria,2HPC7@201174|Actinobacteria,4CQQB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2751667_9	469383.Cwoe_5235	9.838e-46	171.0	COG1278@1|root,COG1278@2|Bacteria,2HR26@201174|Actinobacteria,4CSWY@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SRR25158433_k127_2751667_12	1380390.JIAT01000009_gene711	7.169e-43	162.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4CQR5@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158433_k127_2751667_4	1051632.TPY_1071	2.004e-111	368.0	COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,24CYU@186801|Clostridia	186801|Clostridia	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158433_k127_2751667_11	469383.Cwoe_5229	4.085e-44	174.0	2BHC2@1|root,32BDR@2|Bacteria,2HQHF@201174|Actinobacteria,4CS2N@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158433_k127_2751667_7	469383.Cwoe_5227	1.335e-77	270.0	COG2220@1|root,COG2220@2|Bacteria,2HP2V@201174|Actinobacteria,4CQDX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158433_k127_2751667_3	469383.Cwoe_5222	3.293e-130	422.0	COG0208@1|root,COG0208@2|Bacteria,2GK48@201174|Actinobacteria,4CSBG@84995|Rubrobacteria	84995|Rubrobacteria	F	Ribonucleotide reductase, small chain	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRR25158433_k127_2751667_5	469383.Cwoe_5221	1.448e-99	344.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4CPHK@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158433_k127_2751667_1	1283299.AUKG01000003_gene610	2.415e-220	698.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CRM8@84995|Rubrobacteria	84995|Rubrobacteria	EH	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158433_k127_2751667_6	469383.Cwoe_5209	3.939e-97	326.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CPJE@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158433_k127_2751667_10	448385.sce7871	2e-44	182.0	COG4938@1|root,COG4938@2|Bacteria,1NEEG@1224|Proteobacteria,42QXD@68525|delta/epsilon subdivisions,2WQNW@28221|Deltaproteobacteria,2Z205@29|Myxococcales	28221|Deltaproteobacteria	D	Protein of unknown function (DUF3696)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
SRR25158433_k127_2751667_8	1283299.AUKG01000001_gene1628	9.728e-77	281.0	COG2304@1|root,COG2911@1|root,COG3209@1|root,COG5184@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TIG
SRR25158433_k127_2760053_0	1283299.AUKG01000001_gene1474	1.128e-118	389.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2HPUE@201174|Actinobacteria,4CR88@84995|Rubrobacteria	84995|Rubrobacteria	M	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
SRR25158433_k127_2760053_1	469383.Cwoe_0788	9.372e-96	319.0	COG1573@1|root,COG1573@2|Bacteria,2HNTA@201174|Actinobacteria,4CQ1J@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158433_k127_2760053_2	469383.Cwoe_5328	6.593e-68	239.0	COG3132@1|root,COG3132@2|Bacteria,2I5BV@201174|Actinobacteria,4CSYU@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function, DUF480	-	-	-	-	-	-	-	-	-	-	-	-	DUF480
SRR25158433_k127_2786850_1	1283299.AUKG01000005_gene64	1.073e-82	276.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158433_k127_2786850_4	469383.Cwoe_2657	2.063e-42	163.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4CQME@84995|Rubrobacteria	84995|Rubrobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158433_k127_2786850_3	469383.Cwoe_2656	4.354e-52	192.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4CQFJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158433_k127_2786850_2	469383.Cwoe_2655	2.342e-55	202.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CQ2Q@84995|Rubrobacteria	84995|Rubrobacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158433_k127_2786850_0	1283299.AUKG01000005_gene72	2.949e-91	319.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria	84995|Rubrobacteria	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158433_k127_2786850_5	1235457.C404_13690	1.991e-10	64.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,1K21B@119060|Burkholderiaceae	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158433_k127_2790880_0	469383.Cwoe_4755	8.136e-129	424.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CPS1@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_2790880_1	469383.Cwoe_1788	1.398e-62	232.0	COG4942@1|root,COG4942@2|Bacteria,2GP1Y@201174|Actinobacteria,4CPU0@84995|Rubrobacteria	84995|Rubrobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158433_k127_2809115_4	469383.Cwoe_4990	1.522e-124	426.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158433_k127_2809115_2	469383.Cwoe_1309	2.725e-179	570.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158433_k127_2809115_11	1304865.JAGF01000001_gene1440	1.507e-09	63.0	COG1669@1|root,COG1669@2|Bacteria,2GR6M@201174|Actinobacteria	201174|Actinobacteria	K	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,NTP_transf_2
SRR25158433_k127_2809115_9	469383.Cwoe_2650	1.203e-24	111.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2809115_8	1343740.M271_11730	9.131e-60	214.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph1	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2,Hydrolase_like
SRR25158433_k127_2809115_5	1380370.JIBA01000013_gene1272	5.733e-97	327.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4FEJA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Cytochrome C oxidase assembly protein	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158433_k127_2809115_3	1380347.JNII01000005_gene3218	6.083e-169	542.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4ETMT@85013|Frankiales	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158433_k127_2809115_1	749414.SBI_00351	2.516e-256	824.0	COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158433_k127_2809115_0	404589.Anae109_2025	1.061e-310	964.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2YUJ3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158433_k127_2809115_6	1283299.AUKG01000001_gene3236	2.314e-94	332.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRJD@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158433_k127_2809115_10	221288.JH992901_gene3767	1.146e-12	80.0	COG0823@1|root,COG0823@2|Bacteria,1G8I3@1117|Cyanobacteria	1117|Cyanobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158433_k127_2809115_13	1410634.JHVD01000006_gene1251	5.952e-09	66.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4DR1A@85009|Propionibacteriales	201174|Actinobacteria	T	zinc-ribbon domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158433_k127_2809115_12	1292034.OR37_01459	2.229e-09	61.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2TU68@28211|Alphaproteobacteria,2KF95@204458|Caulobacterales	204458|Caulobacterales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158433_k127_2884707_4	1121935.AQXX01000144_gene4306	1.922e-23	115.0	COG0689@1|root,COG2931@1|root,COG5276@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XKU1@135619|Oceanospirillales	135619|Oceanospirillales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,HemolysinCabind,Laminin_G_3
SRR25158433_k127_2884707_5	1282360.ABAC460_14515	4.933e-08	63.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2KIH3@204458|Caulobacterales	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PPC,Peptidase_M10_C
SRR25158433_k127_2884707_3	1027273.GZ77_25885	2.312e-37	160.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XM3T@135619|Oceanospirillales	135619|Oceanospirillales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158433_k127_2884707_8	1283299.AUKG01000001_gene1396	0.0009894	52.0	COG0394@1|root,COG0394@2|Bacteria,2HFR2@201174|Actinobacteria,4CT4Z@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
SRR25158433_k127_2884707_1	469383.Cwoe_0591	1.385e-91	315.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4CQ49@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158433_k127_2884707_2	469383.Cwoe_0590	8.711e-63	216.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4CQTZ@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158433_k127_2884707_0	222534.KB893729_gene5672	2.765e-99	329.0	COG0580@1|root,COG0580@2|Bacteria,2GMG4@201174|Actinobacteria,4EV3E@85013|Frankiales	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	MIP
SRR25158433_k127_2884707_7	477641.MODMU_0815	1.419e-05	54.0	COG5654@1|root,COG5654@2|Bacteria,2IHX0@201174|Actinobacteria	201174|Actinobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158433_k127_2884707_6	1187851.A33M_0437	1.608e-07	57.0	2AF64@1|root,3154Z@2|Bacteria,1RJ9E@1224|Proteobacteria,2U9GE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRR25158433_k127_2903262_6	469383.Cwoe_5241	3.396e-97	330.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158433_k127_2903262_7	1172185.KB911511_gene3121	4.73e-78	273.0	COG0179@1|root,COG0179@2|Bacteria,2GMSJ@201174|Actinobacteria,4G0UR@85025|Nocardiaceae	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158433_k127_2903262_14	1209984.BN978_05960	1.697e-32	136.0	2FDMJ@1|root,345NT@2|Bacteria,2GS99@201174|Actinobacteria,23C1K@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2903262_9	266117.Rxyl_0203	7.053e-61	229.0	COG0726@1|root,COG0726@2|Bacteria,2IPH5@201174|Actinobacteria,4CSN4@84995|Rubrobacteria	84995|Rubrobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158433_k127_2903262_1	1068978.AMETH_6089	7.641e-202	638.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4E059@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phytoene dehydrogenase-like oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158433_k127_2903262_0	1068978.AMETH_6088	2.511e-214	679.0	2CB1C@1|root,2Z7M2@2|Bacteria,2GM87@201174|Actinobacteria	201174|Actinobacteria	S	Transmembrane protein of unknown function (DUF3556)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3556
SRR25158433_k127_2903262_5	469383.Cwoe_1557	1.781e-117	386.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4CT0Z@84995|Rubrobacteria	84995|Rubrobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158433_k127_2903262_10	1283299.AUKG01000002_gene4023	5.781e-58	209.0	COG1024@1|root,COG1024@2|Bacteria,2IR3N@201174|Actinobacteria,4CPQS@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158433_k127_2903262_8	469383.Cwoe_5242	2.106e-70	246.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CQJ6@84995|Rubrobacteria	84995|Rubrobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158433_k127_2903262_13	1380390.JIAT01000009_gene727	7.36e-46	178.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CQ60@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158433_k127_2903262_4	469383.Cwoe_1051	3.057e-138	454.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158433_k127_2903262_12	479431.Namu_2597	1.943e-48	186.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IDNP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2903262_11	469383.Cwoe_5805	1.808e-56	207.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158433_k127_2903262_15	754035.Mesau_01316	3.965e-10	72.0	2EK0M@1|root,33DR5@2|Bacteria,1NKNS@1224|Proteobacteria,2UNJZ@28211|Alphaproteobacteria,43P8N@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
SRR25158433_k127_2903262_3	1283299.AUKG01000003_gene570	1.927e-146	473.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CPAI@84995|Rubrobacteria	84995|Rubrobacteria	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158433_k127_2903262_2	469383.Cwoe_5251	7.026e-158	511.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CPJI@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
SRR25158433_k127_2908217_50	1380390.JIAT01000010_gene4495	9.057e-51	201.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CQ8R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158433_k127_2908217_8	469383.Cwoe_3550	3.119e-223	710.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CPQW@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158433_k127_2908217_44	469383.Cwoe_3551	1.29e-71	251.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GN0H@201174|Actinobacteria,4CQKX@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158433_k127_2908217_6	469383.Cwoe_3559	1.937e-232	735.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CP5R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158433_k127_2908217_22	1279017.AQYJ01000029_gene3571	1.064e-140	462.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,1RPIM@1236|Gammaproteobacteria,46DF1@72275|Alteromonadaceae	1236|Gammaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_2908217_73	43989.cce_2195	2.272e-10	73.0	COG2931@1|root,COG2931@2|Bacteria,1GHTZ@1117|Cyanobacteria,3KJHD@43988|Cyanothece	1117|Cyanobacteria	Q	hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158433_k127_2908217_32	525368.HMPREF0591_0938	1.035e-105	353.0	COG0604@1|root,COG0604@2|Bacteria,2GK40@201174|Actinobacteria,233XP@1762|Mycobacteriaceae	201174|Actinobacteria	C	Thought to be involved in fatty acid degradation. FadB and FadA are the alpha and beta subunits of the multifunctional enzyme complex of the fatty acid degradation cycle	fadB5	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158433_k127_2908217_12	469383.Cwoe_3561	2.097e-191	624.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CP5W@84995|Rubrobacteria	84995|Rubrobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158433_k127_2908217_16	246196.MSMEI_5534	5.8e-166	532.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,232BR@1762|Mycobacteriaceae	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158433_k127_2908217_53	469383.Cwoe_1589	1.486e-44	172.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_2908217_19	1283299.AUKG01000002_gene4865	2.028e-147	473.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CPA6@84995|Rubrobacteria	84995|Rubrobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158433_k127_2908217_31	309801.trd_A0308	2.168e-106	364.0	COG0318@1|root,COG0318@2|Bacteria,2G7PF@200795|Chloroflexi,27XJD@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158433_k127_2908217_25	1283299.AUKG01000002_gene4861	1.041e-136	462.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4CPAK@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158433_k127_2908217_39	1283299.AUKG01000002_gene4860	3.696e-94	326.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CQ7T@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158433_k127_2908217_63	1218076.BAYB01000009_gene1845	5.909e-28	126.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2VH1R@28216|Betaproteobacteria,1K2BQ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	mandelate racemase muconate lactonizing	menC	-	4.2.1.113,5.5.1.1	ko:K01856,ko:K02549	ko00130,ko00361,ko00362,ko00364,ko00623,ko01100,ko01110,ko01120,ko01220,map00130,map00361,map00362,map00364,map00623,map01100,map01110,map01120,map01220	M00116,M00568	R04031,R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01053,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158433_k127_2908217_26	1380390.JIAT01000010_gene4465	2.207e-128	430.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4CPYA@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRR25158433_k127_2908217_52	1122939.ATUD01000013_gene920	2.658e-46	180.0	28K6W@1|root,2Z9V8@2|Bacteria,2GNHU@201174|Actinobacteria,4CSYY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2908217_20	469383.Cwoe_3578	2.348e-144	471.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CQEB@84995|Rubrobacteria	84995|Rubrobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158433_k127_2908217_55	1118060.CAGZ01000011_gene1534	3.978e-43	178.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CUNX@84998|Coriobacteriia	84998|Coriobacteriia	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158433_k127_2908217_3	469383.Cwoe_3580	9.516e-274	852.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CPN4@84995|Rubrobacteria	84995|Rubrobacteria	E	Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158433_k127_2908217_14	479434.Sthe_2765	4.652e-181	586.0	COG0451@1|root,COG0451@2|Bacteria,2G5M4@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158433_k127_2908217_68	1280390.CBQR020000151_gene4031	2.539e-20	105.0	COG1807@1|root,COG1807@2|Bacteria,1UYMG@1239|Firmicutes,4HB8M@91061|Bacilli,26ZKF@186822|Paenibacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158433_k127_2908217_60	1122939.ATUD01000004_gene3840	9.979e-37	159.0	29YC3@1|root,30K6G@2|Bacteria,2I7A8@201174|Actinobacteria,4CTY9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2908217_46	266117.Rxyl_1238	5.548e-68	260.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4CU1H@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_2908217_42	1380390.JIAT01000011_gene2681	1.368e-82	295.0	COG2133@1|root,COG2133@2|Bacteria,2H9JT@201174|Actinobacteria,4CQXG@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158433_k127_2908217_69	469383.Cwoe_3581	3.778e-17	91.0	2B7VA@1|root,32124@2|Bacteria,2HRN3@201174|Actinobacteria,4CTQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2908217_17	1283299.AUKG01000004_gene1220	9.873e-163	523.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4CPW0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158433_k127_2908217_13	469383.Cwoe_3584	1.712e-189	605.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CP9F@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158433_k127_2908217_10	469383.Cwoe_3585	9.644e-193	617.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CPBB@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158433_k127_2908217_65	469383.Cwoe_3586	4.672e-27	113.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4CQK8@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158433_k127_2908217_40	469383.Cwoe_1198	9.203e-94	331.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria,4CU60@84995|Rubrobacteria	84995|Rubrobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158433_k127_2908217_41	469383.Cwoe_3588	1.67e-91	329.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CPTY@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158433_k127_2908217_7	469383.Cwoe_3589	6.355e-226	739.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158433_k127_2908217_38	1380390.JIAT01000010_gene4444	5.439e-96	333.0	COG1045@1|root,COG1045@2|Bacteria,2IHW5@201174|Actinobacteria,4CRBB@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
SRR25158433_k127_2908217_28	469383.Cwoe_3593	1.808e-117	386.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPUY@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158433_k127_2908217_54	469383.Cwoe_0944	1.335e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,2ISBJ@201174|Actinobacteria,4CTR1@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158433_k127_2908217_57	240016.ABIZ01000001_gene4025	7.078e-43	163.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158433_k127_2908217_61	469383.Cwoe_3601	7.312e-34	138.0	COG1959@1|root,COG1959@2|Bacteria,2HNE1@201174|Actinobacteria,4CQQM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158433_k127_2908217_70	626887.J057_21180	2.824e-15	83.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,46CIA@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479,ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158433_k127_2908217_30	469383.Cwoe_3603	2.266e-108	361.0	COG1639@1|root,COG2197@1|root,COG1639@2|Bacteria,COG2197@2|Bacteria,2HBP2@201174|Actinobacteria,4CREZ@84995|Rubrobacteria	84995|Rubrobacteria	KT	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HDOD
SRR25158433_k127_2908217_15	469383.Cwoe_3604	2.749e-173	557.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158433_k127_2908217_36	469383.Cwoe_3605	1.581e-101	338.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CP9J@84995|Rubrobacteria	84995|Rubrobacteria	L	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158433_k127_2908217_9	469383.Cwoe_4755	2.969e-218	686.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CPS1@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_2908217_1	1122939.ATUD01000004_gene3875	0.0	1341.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CP98@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158433_k127_2908217_24	1283299.AUKG01000001_gene1590	6.557e-139	476.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2908217_51	469383.Cwoe_5343	1.072e-49	205.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4842,DUF5122
SRR25158433_k127_2908217_76	469383.Cwoe_1428	0.000602	54.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
SRR25158433_k127_2908217_74	31033.ENSTRUP00000034121	6.867e-08	67.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38F95@33154|Opisthokonta,3BA7J@33208|Metazoa,3CZWX@33213|Bilateria,4871K@7711|Chordata,48ZRP@7742|Vertebrata,49TXP@7898|Actinopterygii	33208|Metazoa	O	Tripartite motif containing 71, E3 ubiquitin protein ligase	TRIM71	GO:0000003,GO:0000082,GO:0000278,GO:0000932,GO:0001708,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0002164,GO:0002165,GO:0002168,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005912,GO:0005924,GO:0005927,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006417,GO:0006464,GO:0006725,GO:0006807,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007399,GO:0007517,GO:0007548,GO:0008150,GO:0008152,GO:0008283,GO:0008543,GO:0008544,GO:0009056,GO:0009057,GO:0009653,GO:0009719,GO:0009790,GO:0009791,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009913,GO:0009957,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010586,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010720,GO:0014020,GO:0014070,GO:0016070,GO:0016071,GO:0016203,GO:0016331,GO:0016441,GO:0016458,GO:0016567,GO:0016740,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0019787,GO:0019953,GO:0021915,GO:0022402,GO:0022407,GO:0022414,GO:0023052,GO:0030054,GO:0030055,GO:0030154,GO:0030155,GO:0030371,GO:0030674,GO:0030855,GO:0030856,GO:0031047,GO:0031050,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031331,GO:0032268,GO:0032269,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033628,GO:0033632,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0035148,GO:0035194,GO:0035195,GO:0035196,GO:0035198,GO:0035239,GO:0035278,GO:0035295,GO:0035770,GO:0036211,GO:0036464,GO:0040029,GO:0040033,GO:0040034,GO:0042127,GO:0042221,GO:0043009,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043331,GO:0043412,GO:0043487,GO:0043488,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044344,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0044770,GO:0044772,GO:0044843,GO:0045138,GO:0045165,GO:0045182,GO:0045595,GO:0045597,GO:0045604,GO:0045682,GO:0045935,GO:0045974,GO:0046483,GO:0046661,GO:0046700,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048598,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0050779,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051704,GO:0051716,GO:0051865,GO:0060090,GO:0060147,GO:0060148,GO:0060255,GO:0060281,GO:0060282,GO:0060284,GO:0060378,GO:0060429,GO:0060538,GO:0060562,GO:0060606,GO:0060964,GO:0060966,GO:0060968,GO:0061013,GO:0061014,GO:0061061,GO:0061157,GO:0061158,GO:0061630,GO:0061659,GO:0061980,GO:0065007,GO:0065008,GO:0070161,GO:0070647,GO:0070848,GO:0070887,GO:0070918,GO:0071310,GO:0071359,GO:0071363,GO:0071407,GO:0071495,GO:0071704,GO:0071774,GO:0072089,GO:0072175,GO:0080090,GO:0090304,GO:0090598,GO:0090727,GO:0097159,GO:0140096,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901575,GO:1901698,GO:1901699,GO:1903047,GO:1903311,GO:1903313,GO:1905879,GO:1905881,GO:1990124,GO:1990904,GO:2000026,GO:2000112,GO:2000113,GO:2000177,GO:2000241,GO:2000243,GO:2000637	2.3.2.27	ko:K12035	ko05206,map05206	-	-	-	ko00000,ko00001,ko01000,ko03019,ko04121	-	-	-	Filamin,NHL,zf-B_box
SRR25158433_k127_2908217_34	469383.Cwoe_3240	2.281e-103	340.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CPKW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158433_k127_2908217_35	469383.Cwoe_3239	3.644e-102	359.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4CR95@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158433_k127_2908217_5	1380390.JIAT01000010_gene4822	3.929e-252	787.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CPQX@84995|Rubrobacteria	84995|Rubrobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158433_k127_2908217_43	994479.GL877879_gene4526	2.288e-73	261.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4E2HM@85010|Pseudonocardiales	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158433_k127_2908217_45	469383.Cwoe_3234	6.515e-70	269.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158433_k127_2908217_21	469383.Cwoe_3233	1.723e-142	463.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158433_k127_2908217_2	1380390.JIAT01000010_gene4832	9.075e-316	982.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CPRU@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158433_k127_2908217_59	1283299.AUKG01000002_gene5181	2.715e-42	162.0	COG1651@1|root,COG1651@2|Bacteria,2HP1Q@201174|Actinobacteria,4CQC8@84995|Rubrobacteria	84995|Rubrobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
SRR25158433_k127_2908217_56	1283299.AUKG01000002_gene5183	7e-43	161.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4CPZP@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158433_k127_2908217_62	469383.Cwoe_3228	1.635e-33	133.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CQF0@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158433_k127_2908217_37	1283299.AUKG01000002_gene5185	2.019e-99	334.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CPIB@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158433_k127_2908217_48	1283299.AUKG01000002_gene5186	1.128e-62	231.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CPY4@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_N
SRR25158433_k127_2908217_29	1283299.AUKG01000002_gene5187	2.03e-108	364.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4CPFM@84995|Rubrobacteria	84995|Rubrobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158433_k127_2908217_64	469383.Cwoe_3223	1.71e-27	121.0	COG0858@1|root,COG0858@2|Bacteria,2HPFC@201174|Actinobacteria,4CQTS@84995|Rubrobacteria	84995|Rubrobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158433_k127_2908217_4	469383.Cwoe_3221	1.203e-256	811.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158433_k127_2908217_11	469383.Cwoe_3219	1.665e-191	613.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CPEF@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158433_k127_2908217_71	469383.Cwoe_3218	1.261e-13	74.0	COG0779@1|root,COG0779@2|Bacteria,2HPFT@201174|Actinobacteria,4CQU9@84995|Rubrobacteria	84995|Rubrobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158433_k127_2908217_23	1380390.JIAT01000010_gene4848	1.664e-139	457.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CQAJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158433_k127_2908217_66	1283299.AUKG01000002_gene5197	6.459e-26	116.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4CQGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158433_k127_2908217_49	469383.Cwoe_3208	1.66e-55	207.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158433_k127_2908217_58	469383.Cwoe_3207	1.512e-42	160.0	2AU98@1|root,31JWM@2|Bacteria,2HNY8@201174|Actinobacteria,4CQ7F@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2908217_33	469383.Cwoe_3206	1.478e-105	349.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CQPU@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158433_k127_2908217_47	469383.Cwoe_3205	8.002e-65	233.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4CTMJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind
SRR25158433_k127_2908217_0	469383.Cwoe_3204	0.0	1418.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CPEA@84995|Rubrobacteria	84995|Rubrobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158433_k127_2908217_18	929712.KI912613_gene3549	2.49e-155	512.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CP5S@84995|Rubrobacteria	84995|Rubrobacteria	EF	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158433_k127_2908217_27	1380390.JIAT01000010_gene4856	3.835e-120	392.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CPDG@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158433_k127_2911290_0	1157640.AQWO01000016_gene901	0.0	1464.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_2924009_4	469383.Cwoe_5343	1.455e-14	86.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4842,DUF5122
SRR25158433_k127_2924009_3	525904.Tter_0038	6.335e-64	239.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158433_k127_2924009_1	1382306.JNIM01000001_gene2598	8.299e-136	442.0	COG2046@1|root,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of activated sulfate	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158433_k127_2924009_2	469383.Cwoe_5533	6.33e-71	248.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4CQ9K@84995|Rubrobacteria	84995|Rubrobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158433_k127_2924009_0	469383.Cwoe_5531	5.108e-297	921.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158433_k127_2976387_11	469383.Cwoe_3786	1.413e-114	386.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5
SRR25158433_k127_2976387_14	469383.Cwoe_1540	4.247e-106	360.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,4CR0Z@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158433_k127_2976387_33	1380390.JIAT01000011_gene2766	2.187e-20	100.0	2AUSI@1|root,31KFK@2|Bacteria,2HPAD@201174|Actinobacteria,4CQNT@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2976387_9	929712.KI912613_gene4841	7.538e-125	405.0	COG0767@1|root,COG0767@2|Bacteria,2IAUN@201174|Actinobacteria,4CR2S@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158433_k127_2976387_10	1380390.JIAT01000011_gene2768	2.148e-124	430.0	COG0767@1|root,COG0767@2|Bacteria,2GJ27@201174|Actinobacteria,4CPTC@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158433_k127_2976387_8	469383.Cwoe_1621	1.206e-127	414.0	COG1127@1|root,COG1127@2|Bacteria,2GJ1T@201174|Actinobacteria,4CPHI@84995|Rubrobacteria	84995|Rubrobacteria	Q	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158433_k127_2976387_3	1380390.JIAT01000011_gene2776	2.007e-170	564.0	COG1033@1|root,COG1033@2|Bacteria,2I731@201174|Actinobacteria,4CR6J@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158433_k127_2976387_32	1380390.JIAT01000011_gene2777	3.443e-23	113.0	COG1225@1|root,COG1225@2|Bacteria,2HT4T@201174|Actinobacteria,4CSH8@84995|Rubrobacteria	84995|Rubrobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158433_k127_2976387_22	469383.Cwoe_1630	1.55e-53	199.0	COG3382@1|root,COG3382@2|Bacteria,2HAYZ@201174|Actinobacteria,4CT9S@84995|Rubrobacteria	84995|Rubrobacteria	S	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2976387_24	469383.Cwoe_5349	7.371e-43	182.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF11,DUF5122,SGL
SRR25158433_k127_2976387_39	469383.Cwoe_1428	0.0003424	55.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
SRR25158433_k127_2976387_38	357808.RoseRS_2986	7.487e-09	70.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
SRR25158433_k127_2976387_28	1283299.AUKG01000001_gene2865	1.977e-27	123.0	2FIW0@1|root,34AM7@2|Bacteria,2HPD8@201174|Actinobacteria,4CQR1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2976387_35	1283299.AUKG01000001_gene2866	1.934e-17	87.0	2BH9C@1|root,32BAU@2|Bacteria,2HP96@201174|Actinobacteria,4CQMF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2976387_29	1380390.JIAT01000011_gene2782	9.793e-26	112.0	2AU98@1|root,30HFP@2|Bacteria,2HYG7@201174|Actinobacteria,4CQNQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2976387_2	1380390.JIAT01000011_gene2783	2.3e-184	587.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CP6E@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class I and II	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158433_k127_2976387_6	469383.Cwoe_1636	1.218e-138	450.0	COG0454@1|root,COG0456@2|Bacteria,2GNAV@201174|Actinobacteria,4CQ54@84995|Rubrobacteria	84995|Rubrobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2976387_20	469383.Cwoe_1638	2.615e-58	213.0	COG0122@1|root,COG0122@2|Bacteria,2HPWW@201174|Actinobacteria,4CRBJ@84995|Rubrobacteria	84995|Rubrobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158433_k127_2976387_7	402777.KB235898_gene5792	2.41e-131	447.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9
SRR25158433_k127_2976387_15	929712.KI912613_gene4827	2.224e-84	292.0	COG0715@1|root,COG0715@2|Bacteria,2HFU1@201174|Actinobacteria,4CQ47@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
SRR25158433_k127_2976387_18	469383.Cwoe_1643	9.599e-65	229.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CQ5D@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158433_k127_2976387_17	326424.FRAAL1558	3.693e-76	265.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EU1S@85013|Frankiales	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
SRR25158433_k127_2976387_16	469383.Cwoe_5534	9.692e-83	285.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4CRVC@84995|Rubrobacteria	84995|Rubrobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158433_k127_2976387_21	1380390.JIAT01000009_gene1158	1.314e-54	195.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158433_k127_2976387_34	1205910.B005_0285	2.933e-20	103.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4EJFE@85012|Streptosporangiales	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158433_k127_2976387_36	56780.SYN_03611	6.05e-17	90.0	COG0317@1|root,COG0317@2|Bacteria,1RKVU@1224|Proteobacteria	1224|Proteobacteria	KT	Guanosine polyphosphate	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158433_k127_2976387_40	622637.KE124774_gene4037	0.0006493	51.0	COG1733@1|root,COG1733@2|Bacteria,1R6MK@1224|Proteobacteria,2U2KM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
SRR25158433_k127_2976387_23	742765.HMPREF9457_01281	3.72e-44	176.0	COG2265@1|root,COG2265@2|Bacteria,1UK4G@1239|Firmicutes,24H6A@186801|Clostridia,27W5R@189330|Dorea	186801|Clostridia	J	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158433_k127_2976387_27	1283299.AUKG01000001_gene3123	1.532e-38	149.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4CU3T@84995|Rubrobacteria	84995|Rubrobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	FxsA
SRR25158433_k127_2976387_1	469383.Cwoe_1834	7.866e-191	606.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CPIV@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158433_k127_2976387_5	469383.Cwoe_1837	7.894e-144	465.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158433_k127_2976387_25	469383.Cwoe_1839	2.232e-40	160.0	COG0526@1|root,COG0526@2|Bacteria,2GKDT@201174|Actinobacteria,4CRTZ@84995|Rubrobacteria	84995|Rubrobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158433_k127_2976387_30	1267534.KB906758_gene2324	1.431e-25	117.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
SRR25158433_k127_2976387_13	469383.Cwoe_5770	4.517e-108	370.0	COG0348@1|root,COG0348@2|Bacteria,2I6I5@201174|Actinobacteria,4CS5U@84995|Rubrobacteria	84995|Rubrobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_2976387_4	1202768.JROF01000020_gene3479	1.06e-146	480.0	COG0665@1|root,COG0723@1|root,arCOG00755@2157|Archaea,arCOG01720@2157|Archaea,2XV4K@28890|Euryarchaeota,23RYI@183963|Halobacteria	183963|Halobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158433_k127_2976387_12	1122939.ATUD01000009_gene3117	3.573e-114	379.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158433_k127_2976387_0	469383.Cwoe_5394	1.871e-261	812.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158433_k127_2976387_26	469383.Cwoe_5395	3.716e-40	151.0	COG2146@1|root,COG2146@2|Bacteria,2HPIQ@201174|Actinobacteria,4CQW9@84995|Rubrobacteria	84995|Rubrobacteria	P	Rieske 2Fe-2S iron-sulphur domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158433_k127_2976387_19	479433.Caci_4804	6.118e-64	228.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158433_k127_29785_0	1380390.JIAT01000010_gene3508	0.0	1085.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158433_k127_29785_7	1283299.AUKG01000002_gene4285	1.707e-15	79.0	290AJ@1|root,2ZN05@2|Bacteria,2HRSY@201174|Actinobacteria,4CTW7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_29785_2	469383.Cwoe_4251	6.237e-45	172.0	COG0389@1|root,COG0389@2|Bacteria,2HPPZ@201174|Actinobacteria,4CR2N@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family	-	-	-	-	-	-	-	-	-	-	-	-	IMS
SRR25158433_k127_29785_5	1283299.AUKG01000002_gene3613	2.626e-22	103.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CSIJ@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_29785_1	1283299.AUKG01000001_gene1590	1.462e-126	442.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_29785_3	1283299.AUKG01000001_gene3551	9.725e-35	156.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158433_k127_29785_4	1121403.AUCV01000031_gene2838	3.156e-24	121.0	COG1361@1|root,COG3540@1|root,COG4733@1|root,COG1361@2|Bacteria,COG3540@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA_membrane
SRR25158433_k127_29785_8	1035308.AQYY01000001_gene1509	2.806e-07	65.0	COG3386@1|root,COG4932@1|root,COG5184@1|root,COG3386@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,1UNN0@1239|Firmicutes,24K2B@186801|Clostridia	2|Bacteria	DMUZ	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SGL
SRR25158433_k127_29785_6	521011.Mpal_1345	7.962e-17	97.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158433_k127_3012637_0	1463825.JNXC01000057_gene6353	0.0	1452.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4E234@85010|Pseudonocardiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	ko:K12436	-	-	-	-	ko00000,ko01004	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158433_k127_3017538_1	1380390.JIAT01000009_gene1911	4.1e-116	379.0	COG1648@1|root,COG1648@2|Bacteria,2GTES@201174|Actinobacteria,4CQK2@84995|Rubrobacteria	84995|Rubrobacteria	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158433_k127_3017538_2	469383.Cwoe_5336	9.766e-61	218.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CQJI@84995|Rubrobacteria	84995|Rubrobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158433_k127_3017538_0	469383.Cwoe_5426	5.074e-148	473.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158433_k127_3018953_1	105420.BBPO01000064_gene3813	7.108e-61	220.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	pfaA	-	-	ko:K04791	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_3018953_0	882086.SacxiDRAFT_0063	9.222e-219	694.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4E234@85010|Pseudonocardiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158433_k127_3035591_3	469383.Cwoe_4225	4.489e-153	496.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,4CRGY@84995|Rubrobacteria	84995|Rubrobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158433_k127_3035591_4	469383.Cwoe_1770	4.987e-109	368.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRAY@84995|Rubrobacteria	201174|Actinobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158433_k127_3035591_0	469383.Cwoe_4232	1.484e-253	797.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158433_k127_3035591_1	1122939.ATUD01000007_gene1983	1.758e-210	679.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4CRVY@84995|Rubrobacteria	84995|Rubrobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_3035591_2	485915.Dret_2389	3.962e-179	572.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2M8XA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158433_k127_3035591_5	469383.Cwoe_4244	2.941e-48	179.0	COG2128@1|root,COG2128@2|Bacteria,2HNSY@201174|Actinobacteria,4CQ13@84995|Rubrobacteria	84995|Rubrobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158433_k127_3042906_7	1341151.ASZU01000004_gene137	2.344e-70	255.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27BIU@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158433_k127_3042906_6	469383.Cwoe_4521	6.003e-77	278.0	COG0639@1|root,COG0639@2|Bacteria,2HNQI@201174|Actinobacteria,4CPX1@84995|Rubrobacteria	84995|Rubrobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158433_k127_3042906_2	469383.Cwoe_4517	9.527e-185	599.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CP8V@84995|Rubrobacteria	84995|Rubrobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158433_k127_3042906_24	1123256.KB907953_gene3131	0.0002144	53.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,1X4IE@135614|Xanthomonadales	135614|Xanthomonadales	D	protein involved in exopolysaccharide biosynthesis	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,GNVR,Wzz
SRR25158433_k127_3042906_15	1380390.JIAT01000015_gene5704	2.309e-28	120.0	COG3088@1|root,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria,4CT29@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158433_k127_3042906_14	469383.Cwoe_4515	6.576e-29	122.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4CQ9G@84995|Rubrobacteria	84995|Rubrobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158433_k127_3042906_23	1120945.ATUW01000005_gene623	9.764e-05	46.0	2ASDQ@1|root,31HT6@2|Bacteria,2HMBW@201174|Actinobacteria,4D6R3@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3042906_18	469383.Cwoe_1482	6.71e-16	87.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CRPW@84995|Rubrobacteria	84995|Rubrobacteria	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158433_k127_3042906_22	467200.ACFA01000743_gene1851	1.851e-06	55.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158433_k127_3042906_3	1283299.AUKG01000001_gene2083	2.121e-169	567.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3042906_4	1283299.AUKG01000001_gene2260	2.771e-88	302.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4CQZV@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158433_k127_3042906_5	469383.Cwoe_2667	7.361e-81	278.0	COG4221@1|root,COG4221@2|Bacteria,2IAVE@201174|Actinobacteria,4CR7Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_3042906_13	1122939.ATUD01000007_gene2011	5.083e-33	132.0	COG2332@1|root,COG2332@2|Bacteria,2HP5E@201174|Actinobacteria,4CQHD@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmE	-	-	-	-	-	-	-	-	-	-	-	-	CcmE
SRR25158433_k127_3042906_0	1283299.AUKG01000002_gene4199	2.176e-215	697.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CRCE@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158433_k127_3042906_17	1380390.JIAT01000015_gene5799	5.94e-21	95.0	COG1314@1|root,COG1314@2|Bacteria,2HP6M@201174|Actinobacteria,4CQIR@84995|Rubrobacteria	84995|Rubrobacteria	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
SRR25158433_k127_3042906_1	469383.Cwoe_5739	1.169e-212	664.0	COG3239@1|root,COG3239@2|Bacteria,2GIWV@201174|Actinobacteria,4CRJF@84995|Rubrobacteria	84995|Rubrobacteria	CI	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase,Rubredoxin
SRR25158433_k127_3042906_16	469383.Cwoe_5738	2.897e-23	110.0	COG1773@1|root,COG1773@2|Bacteria,2GQUH@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the rubredoxin family	alkG	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
SRR25158433_k127_3042906_8	469383.Cwoe_5737	1.068e-67	240.0	COG1309@1|root,COG1309@2|Bacteria,2GMDA@201174|Actinobacteria,4CT7V@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3042906_19	590409.Dd586_1695	9.587e-12	73.0	COG5346@1|root,COG5346@2|Bacteria,1N3Y1@1224|Proteobacteria,1SBSN@1236|Gammaproteobacteria,2JBT7@204037|Dickeya	1236|Gammaproteobacteria	S	Predicted membrane protein (DUF2335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2335
SRR25158433_k127_3042906_10	485913.Krac_0932	5.032e-48	179.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158433_k127_3042906_9	1122939.ATUD01000015_gene996	3.658e-52	196.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4CQCM@84995|Rubrobacteria	84995|Rubrobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158433_k127_3042906_12	1380386.JIAW01000003_gene632	1.849e-38	154.0	COG0500@1|root,COG2226@2|Bacteria,2HRZ9@201174|Actinobacteria,239M3@1762|Mycobacteriaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158433_k127_3042906_11	1051632.TPY_1878	3.339e-40	155.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,24HA8@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790,ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158433_k127_3042906_20	1458427.BAWN01000013_gene769	5.779e-07	57.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VNAZ@28216|Betaproteobacteria,4AAES@80864|Comamonadaceae	28216|Betaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158433_k127_3071735_0	1157638.KB892174_gene342	0.0	1167.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_3103847_7	1380390.JIAT01000009_gene1911	1.621e-30	133.0	COG1648@1|root,COG1648@2|Bacteria,2GTES@201174|Actinobacteria,4CQK2@84995|Rubrobacteria	84995|Rubrobacteria	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158433_k127_3103847_1	469383.Cwoe_5315	8.65e-113	371.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4CRA0@84995|Rubrobacteria	84995|Rubrobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158433_k127_3103847_0	266117.Rxyl_1964	2.693e-198	643.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2GJU7@201174|Actinobacteria,4CPD0@84995|Rubrobacteria	84995|Rubrobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158433_k127_3103847_6	1380390.JIAT01000009_gene2260	6.372e-46	173.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CQ6G@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158433_k127_3103847_3	469383.Cwoe_5416	2.659e-62	229.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CQDV@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158433_k127_3103847_8	1280390.CBQR020000010_gene289	1.353e-05	57.0	COG2456@1|root,COG2456@2|Bacteria,1UPVP@1239|Firmicutes,4HNQC@91061|Bacilli,26YN9@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
SRR25158433_k127_3103847_4	717606.PaecuDRAFT_1629	1.39e-60	218.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,4HDKY@91061|Bacilli,26U9S@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl transferase family 2	ycbB	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
SRR25158433_k127_3103847_5	266117.Rxyl_2982	9.231e-57	214.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158433_k127_3103847_2	266117.Rxyl_0378	6.059e-65	232.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CPX6@84995|Rubrobacteria	84995|Rubrobacteria	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158433_k127_3123146_3	469383.Cwoe_0896	2.571e-60	214.0	COG0739@1|root,COG3409@1|root,COG0739@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,PG_binding_1,Peptidase_M23
SRR25158433_k127_3123146_7	498761.HM1_3104	2.443e-22	102.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,25ESC@186801|Clostridia	186801|Clostridia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158433_k127_3123146_8	1299327.I546_6550	3.49e-21	105.0	COG3832@1|root,COG3832@2|Bacteria,2IRJC@201174|Actinobacteria,238BC@1762|Mycobacteriaceae	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3123146_5	1283299.AUKG01000001_gene3551	5.102e-39	169.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158433_k127_3123146_9	768704.Desmer_1347	7.308e-17	96.0	COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,1V2E4@1239|Firmicutes,24TKC@186801|Clostridia	186801|Clostridia	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158433_k127_3123146_10	266940.Krad_0465	8.804e-11	64.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158433_k127_3123146_1	1283299.AUKG01000001_gene1590	4.272e-133	460.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3123146_4	1283299.AUKG01000001_gene3551	4.122e-42	180.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158433_k127_3123146_11	768704.Desmer_1347	1.251e-10	76.0	COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,1V2E4@1239|Firmicutes,24TKC@186801|Clostridia	186801|Clostridia	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SRR25158433_k127_3123146_2	1283299.AUKG01000003_gene502	4.241e-79	280.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158433_k127_3123146_0	1068980.ARVW01000001_gene4934	3.819e-192	618.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158433_k127_3123146_6	469383.Cwoe_5292	2.834e-29	119.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4CQFN@84995|Rubrobacteria	84995|Rubrobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158433_k127_3123146_12	1283299.AUKG01000003_gene500	9.213e-08	59.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158433_k127_3136216_9	1380390.JIAT01000001_gene5010	1.483e-29	119.0	COG0573@1|root,COG0573@2|Bacteria,2ISS5@201174|Actinobacteria,4CPV6@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158433_k127_3136216_4	1380390.JIAT01000001_gene5009	1.78e-110	370.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CPG4@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158433_k127_3136216_1	469383.Cwoe_4769	4.845e-128	416.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CPBX@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158433_k127_3136216_8	1283299.AUKG01000003_gene703	1.04e-33	149.0	2AW64@1|root,31N14@2|Bacteria,2HQPV@201174|Actinobacteria,4CSBV@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3136216_11	1380390.JIAT01000001_gene5006	9.47e-14	84.0	2ATAQ@1|root,31ITS@2|Bacteria,2HN77@201174|Actinobacteria,4CQKU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3136216_10	1380390.JIAT01000001_gene5005	1.81e-29	130.0	29Z0D@1|root,30KXH@2|Bacteria,2HP8W@201174|Actinobacteria,4CQM4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3136216_12	1283299.AUKG01000002_gene4022	9.696e-07	54.0	2AXHB@1|root,32I9X@2|Bacteria,2HRFS@201174|Actinobacteria,4CTEM@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3136216_0	469383.Cwoe_5676	5.865e-133	428.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria	84995|Rubrobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158433_k127_3136216_5	1122939.ATUD01000007_gene2049	3.207e-107	355.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CPSW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158433_k127_3136216_3	469383.Cwoe_4492	1.768e-122	401.0	COG0226@1|root,COG0226@2|Bacteria,2H61B@201174|Actinobacteria,4CTXY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	-
SRR25158433_k127_3136216_6	469383.Cwoe_4493	7.512e-106	356.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158433_k127_3136216_2	469383.Cwoe_4494	5.479e-123	409.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158433_k127_3136216_7	469383.Cwoe_4495	2.306e-63	222.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CP9Q@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158433_k127_3145773_2	1283299.AUKG01000001_gene3087	4.046e-44	175.0	COG3857@1|root,COG3857@2|Bacteria,2HNUC@201174|Actinobacteria,4CQ2I@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158433_k127_3145773_0	1283299.AUKG01000001_gene3121	3.382e-68	234.0	2AW45@1|root,31MZ2@2|Bacteria,2HNU6@201174|Actinobacteria,4CQ2D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3145773_1	469383.Cwoe_1828	3.988e-68	239.0	COG1011@1|root,COG1011@2|Bacteria,2HP8B@201174|Actinobacteria,4CTW5@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158433_k127_3145773_5	469383.Cwoe_1829	2.605e-17	86.0	2AZ12@1|root,31R76@2|Bacteria,2HPZ2@201174|Actinobacteria,4CREC@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3145773_3	469383.Cwoe_1832	8.918e-35	146.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CQHE@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158433_k127_3145773_4	521011.Mpal_0423	4.486e-18	98.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
SRR25158433_k127_3150429_0	42256.RradSPS_0557	5.154e-112	371.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158433_k127_3150429_4	469383.Cwoe_4689	2.657e-40	171.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4CQFX@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158433_k127_3150429_5	649638.Trad_1462	1.706e-32	144.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158433_k127_3150429_2	65393.PCC7424_4202	1.442e-64	245.0	COG4424@1|root,COG4424@2|Bacteria,1GQG7@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3150429_1	1380390.JIAT01000009_gene1186	5.588e-79	274.0	COG0392@1|root,COG0392@2|Bacteria,2HNI1@201174|Actinobacteria,4CPH1@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158433_k127_3150429_6	469383.Cwoe_1137	1.087e-26	115.0	2A23K@1|root,30QDU@2|Bacteria,2HRA7@201174|Actinobacteria,4CT74@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3150429_3	882086.SacxiDRAFT_2555	4.877e-57	203.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4E2VK@85010|Pseudonocardiales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158433_k127_3168607_1	469383.Cwoe_1555	2.22e-93	311.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4CRP2@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158433_k127_3168607_2	298655.KI912266_gene3217	3.668e-29	131.0	COG0596@1|root,COG0596@2|Bacteria,2I8EU@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	lipV	GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575	-	ko:K19311	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158433_k127_3168607_0	446462.Amir_2684	0.0	2234.0	COG0300@1|root,COG1028@1|root,COG3321@1|root,COG0300@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4DZDB@85010|Pseudonocardiales	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158433_k127_3194042_1	469383.Cwoe_2882	2.224e-273	851.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158433_k127_3194042_36	1229780.BN381_50045	4.323e-12	74.0	2E2ZZ@1|root,32Y0I@2|Bacteria,2IIJC@201174|Actinobacteria,3UXI1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3194042_28	479435.Kfla_0120	2.318e-45	171.0	COG1708@1|root,COG1708@2|Bacteria,2GUWM@201174|Actinobacteria,4DVAU@85009|Propionibacteriales	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158433_k127_3194042_21	469383.Cwoe_3472	1.503e-72	252.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158433_k127_3194042_42	452652.KSE_27970	3.833e-06	55.0	COG3631@1|root,COG3631@2|Bacteria,2IJQH@201174|Actinobacteria	201174|Actinobacteria	S	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158433_k127_3194042_2	266117.Rxyl_2021	2.029e-265	835.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CPEX@84995|Rubrobacteria	84995|Rubrobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158433_k127_3194042_39	706587.Desti_0590	2.266e-10	64.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,42X7S@68525|delta/epsilon subdivisions,2WSVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158433_k127_3194042_40	1283287.KB822582_gene2954	1.273e-08	64.0	2B6JB@1|root,31ZHQ@2|Bacteria,2II7G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3194042_14	1283283.ATXA01000001_gene334	5.219e-102	350.0	COG0477@1|root,COG0477@2|Bacteria,2IDYF@201174|Actinobacteria,4EUIS@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_3194042_27	929712.KI912613_gene4348	5.552e-46	172.0	COG0741@1|root,COG0741@2|Bacteria,2GWDB@201174|Actinobacteria,4CQ5G@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158433_k127_3194042_26	1380390.JIAT01000016_gene5588	8.927e-50	189.0	COG0237@1|root,COG0237@2|Bacteria,2HG2S@201174|Actinobacteria,4CQK0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158433_k127_3194042_4	469383.Cwoe_2872	1.499e-189	607.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CPF8@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158433_k127_3194042_8	469383.Cwoe_2871	4.971e-159	512.0	COG0644@1|root,COG0644@2|Bacteria,2HQ8K@201174|Actinobacteria,4CRS9@84995|Rubrobacteria	84995|Rubrobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3194042_32	1283299.AUKG01000004_gene1174	2.226e-29	122.0	COG3238@1|root,COG3238@2|Bacteria,2HQYP@201174|Actinobacteria,4CSRF@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
SRR25158433_k127_3194042_11	469383.Cwoe_5348	6.184e-132	456.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3194042_29	1283299.AUKG01000001_gene3551	1.151e-39	172.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158433_k127_3194042_37	269798.CHU_2818	4.932e-12	81.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL
SRR25158433_k127_3194042_0	469383.Cwoe_2867	2.898e-309	972.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRR25158433_k127_3194042_35	1380390.JIAT01000010_gene3619	2.406e-22	106.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158433_k127_3194042_25	471857.Svir_25890	1.804e-53	194.0	COG2020@1|root,COG2020@2|Bacteria,2IIDW@201174|Actinobacteria,4E55T@85010|Pseudonocardiales	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158433_k127_3194042_3	469383.Cwoe_2866	2.55e-204	646.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158433_k127_3194042_19	1380390.JIAT01000016_gene5597	2.488e-77	269.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158433_k127_3194042_7	298655.KI912267_gene7395	6.517e-162	516.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4ERH0@85013|Frankiales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
SRR25158433_k127_3194042_17	1532557.JL37_25410	1.511e-85	291.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158433_k127_3194042_23	1283299.AUKG01000004_gene1189	1.477e-70	249.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4CPX0@84995|Rubrobacteria	84995|Rubrobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158433_k127_3194042_6	469383.Cwoe_2859	9.362e-183	578.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CP72@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158433_k127_3194042_24	1283299.AUKG01000004_gene1192	1.756e-66	232.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CQBZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158433_k127_3194042_16	1380390.JIAT01000016_gene5611	1.114e-89	311.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158433_k127_3194042_15	1380390.JIAT01000016_gene5612	1.761e-90	305.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4CPUD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the TrpC family	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158433_k127_3194042_12	1380390.JIAT01000016_gene5613	1.093e-112	374.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CP6K@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158433_k127_3194042_20	469383.Cwoe_2854	1.686e-76	268.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4CPX3@84995|Rubrobacteria	84995|Rubrobacteria	EH	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158433_k127_3194042_5	1122939.ATUD01000002_gene1440	3.851e-187	599.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CPNJ@84995|Rubrobacteria	84995|Rubrobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158433_k127_3194042_22	1283299.AUKG01000004_gene1198	7.078e-72	249.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CQAR@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR25158433_k127_3194042_10	469383.Cwoe_2994	9.644e-139	465.0	COG1752@1|root,COG1752@2|Bacteria,2ID07@201174|Actinobacteria,4CR54@84995|Rubrobacteria	84995|Rubrobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158433_k127_3194042_13	469383.Cwoe_2851	2.017e-109	367.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CPY3@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158433_k127_3194042_30	1122939.ATUD01000002_gene1435	7.235e-39	152.0	COG0319@1|root,COG0319@2|Bacteria,2HN3K@201174|Actinobacteria,4CQHV@84995|Rubrobacteria	84995|Rubrobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158433_k127_3194042_9	469383.Cwoe_2849	6.718e-155	495.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CPBK@84995|Rubrobacteria	84995|Rubrobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158433_k127_3194042_31	1122939.ATUD01000016_gene1831	5.689e-34	135.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4CQJX@84995|Rubrobacteria	84995|Rubrobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158433_k127_3194042_33	469383.Cwoe_0181	1.775e-25	111.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_3194042_38	469383.Cwoe_0182	1.177e-10	65.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	-	-	-	-	-	-	-	-	-	-	-	-	DUF2924,RHH_1,RHH_3
SRR25158433_k127_3194042_18	469383.Cwoe_1865	1.676e-82	284.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CQ0N@84995|Rubrobacteria	84995|Rubrobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158433_k127_3194042_34	1380390.JIAT01000009_gene2169	1.995e-25	111.0	2B4FA@1|root,31X6X@2|Bacteria,2HQY4@201174|Actinobacteria,4CSQM@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
SRR25158433_k127_3194042_41	929712.KI912613_gene4393	1.937e-08	55.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158433_k127_3199667_12	469383.Cwoe_3111	1.443e-10	63.0	COG1598@1|root,COG1598@2|Bacteria,2GZ8D@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3199667_9	469383.Cwoe_3110	3.855e-18	87.0	COG1724@1|root,COG1724@2|Bacteria,2GX5V@201174|Actinobacteria	201174|Actinobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158433_k127_3199667_5	469383.Cwoe_3010	8.916e-84	289.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
SRR25158433_k127_3199667_6	469383.Cwoe_3011	2.528e-66	237.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CPTU@84995|Rubrobacteria	84995|Rubrobacteria	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158433_k127_3199667_4	1380390.JIAT01000017_gene5310	3.196e-89	306.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4CQ06@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_3199667_2	469383.Cwoe_3015	1.74e-153	495.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CPRI@84995|Rubrobacteria	84995|Rubrobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158433_k127_3199667_1	929712.KI912613_gene3400	7.62e-211	672.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CPG8@84995|Rubrobacteria	84995|Rubrobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158433_k127_3199667_8	469383.Cwoe_1560	4.252e-46	178.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158433_k127_3199667_3	469383.Cwoe_3019	3.44e-143	473.0	COG0482@1|root,COG0822@1|root,COG0482@2|Bacteria,COG0822@2|Bacteria,2GIUQ@201174|Actinobacteria,4CPQ6@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	NifU_N,tRNA_Me_trans
SRR25158433_k127_3199667_7	1122939.ATUD01000001_gene409	2.664e-57	219.0	COG1595@1|root,COG1595@2|Bacteria	1122939.ATUD01000001_gene409|-	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3199667_0	469383.Cwoe_3034	1.89e-301	947.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158433_k127_3201798_5	1380390.JIAT01000009_gene1898	9.243e-16	79.0	COG0340@1|root,COG0340@2|Bacteria,2HGFP@201174|Actinobacteria,4CQNA@84995|Rubrobacteria	84995|Rubrobacteria	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158433_k127_3201798_0	469383.Cwoe_5882	0.0	1103.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4CPIG@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158433_k127_3201798_3	469383.Cwoe_5883	2.401e-49	184.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158433_k127_3201798_6	1128421.JAGA01000002_gene1827	1.452e-10	69.0	COG1030@1|root,COG1030@2|Bacteria,2NNMU@2323|unclassified Bacteria	2|Bacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
SRR25158433_k127_3201798_2	234621.RER_58510	4.38e-106	352.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4FYEC@85025|Nocardiaceae	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158433_k127_3201798_1	469383.Cwoe_5885	1.919e-112	379.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CRCP@84995|Rubrobacteria	84995|Rubrobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRR25158433_k127_3201798_7	521011.Mpal_0423	1.189e-05	58.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
SRR25158433_k127_3201798_4	469383.Cwoe_5887	4.757e-44	167.0	2AU40@1|root,31JQJ@2|Bacteria,2HNUU@201174|Actinobacteria,4CQ3A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3233244_3	469383.Cwoe_3173	1.337e-85	300.0	COG0491@1|root,COG0491@2|Bacteria,2HGYI@201174|Actinobacteria,4CQY2@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_3233244_0	469383.Cwoe_3174	7.049e-188	597.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158433_k127_3233244_4	485913.Krac_8872	2.087e-57	203.0	COG0537@1|root,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi	200795|Chloroflexi	FG	Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT,NUDIX
SRR25158433_k127_3233244_2	469383.Cwoe_3190	1.858e-133	432.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CR9X@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158433_k127_3233244_1	469383.Cwoe_3191	2.844e-150	482.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4CPCC@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158433_k127_3241805_1	469383.Cwoe_0096	8.918e-118	390.0	COG1215@1|root,COG1215@2|Bacteria,2GXGY@201174|Actinobacteria,4CS4U@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158433_k127_3241805_5	1380390.JIAT01000009_gene1683	2.863e-62	220.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CQ5U@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158433_k127_3241805_13	1120936.KB907224_gene2576	1.827e-11	72.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4EIHX@85012|Streptosporangiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158433_k127_3241805_4	1144275.COCOR_02267	2.117e-70	257.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
SRR25158433_k127_3241805_12	1283299.AUKG01000001_gene1648	3.366e-27	121.0	2BJCF@1|root,32DNI@2|Bacteria,2HQBT@201174|Actinobacteria,4CRW5@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158433_k127_3241805_3	469383.Cwoe_1081	5.695e-96	326.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CRD2@84995|Rubrobacteria	84995|Rubrobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158433_k127_3241805_2	1283299.AUKG01000002_gene4021	1.2e-99	331.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4CS7T@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158433_k127_3241805_8	469383.Cwoe_3152	4.336e-36	154.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3241805_9	469383.Cwoe_3153	5.238e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3241805_7	1283299.AUKG01000002_gene5038	4.021e-40	159.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3241805_15	561175.KB894101_gene4660	2.267e-05	57.0	COG1309@1|root,COG1309@2|Bacteria,2INP5@201174|Actinobacteria,4EQD2@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K03577	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N
SRR25158433_k127_3241805_6	469383.Cwoe_3152	4.794e-44	177.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3241805_0	106370.Francci3_2620	3.889e-147	477.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
SRR25158433_k127_3241805_14	469383.Cwoe_4572	1.245e-09	67.0	COG1309@1|root,COG1309@2|Bacteria,2IKGF@201174|Actinobacteria,4CT9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3241805_11	469383.Cwoe_3152	3.431e-28	123.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3241805_10	1380390.JIAT01000009_gene604	7.437e-31	132.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CSIJ@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3248384_5	469383.Cwoe_5348	4.723e-21	108.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3248384_1	469383.Cwoe_5349	1.4e-56	228.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF11,DUF5122,SGL
SRR25158433_k127_3248384_3	1283299.AUKG01000001_gene2684	1.435e-27	132.0	COG4733@1|root,COG4733@2|Bacteria,2HNSD@201174|Actinobacteria,4CSA3@84995|Rubrobacteria	84995|Rubrobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3248384_6	521011.Mpal_0755	2.413e-13	85.0	COG3391@1|root,arCOG03563@2157|Archaea	2157|Archaea	P	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,NHL,PKD
SRR25158433_k127_3248384_2	469383.Cwoe_3152	3.633e-39	157.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3248384_4	469383.Cwoe_3153	2.871e-22	105.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3248384_9	1283299.AUKG01000002_gene3972	1.686e-09	68.0	COG1309@1|root,COG1309@2|Bacteria,2GVR4@201174|Actinobacteria,4CQCN@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3248384_8	1133849.O3I_037220	1.015e-10	74.0	COG1309@1|root,COG1309@2|Bacteria,2ISAC@201174|Actinobacteria,4FY9N@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_3248384_10	1306406.ASHX01000001_gene1826	0.0009359	48.0	COG0642@1|root,COG0745@1|root,COG3290@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG3290@2|Bacteria,2GNWJ@201174|Actinobacteria	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9,Response_reg
SRR25158433_k127_3248384_0	388413.ALPR1_05140	2.188e-74	266.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158433_k127_3248384_7	1120971.AUCA01000003_gene1415	3.719e-13	74.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,27890@186823|Alicyclobacillaceae	91061|Bacilli	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iYO844.BSU27600	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158433_k127_3295019_0	469383.Cwoe_5426	0.0	1032.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158433_k127_3295019_2	1122939.ATUD01000001_gene62	9.799e-148	485.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CPQ8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158433_k127_3295019_7	469383.Cwoe_3047	2.104e-56	203.0	297W1@1|root,2ZV2M@2|Bacteria,2II0V@201174|Actinobacteria,4CT5W@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158433_k127_3295019_18	1380390.JIAT01000009_gene844	4.863e-25	121.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4CQM8@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158433_k127_3295019_1	469383.Cwoe_3715	2.471e-196	641.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158433_k127_3295019_5	1380390.JIAT01000010_gene4197	9.852e-98	330.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158433_k127_3295019_11	469383.Cwoe_3268	1.326e-46	178.0	COG0647@1|root,COG0647@2|Bacteria,2HG8I@201174|Actinobacteria,4CTX4@84995|Rubrobacteria	84995|Rubrobacteria	G	HAD-superfamily hydrolase, subfamily IIA	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158433_k127_3295019_6	219305.MCAG_00443	2.104e-92	323.0	COG0477@1|root,COG0477@2|Bacteria,2I4Y7@201174|Actinobacteria,4DFI9@85008|Micromonosporales	201174|Actinobacteria	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158433_k127_3295019_9	1283299.AUKG01000002_gene5307	4.228e-53	190.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4CQBG@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158433_k127_3295019_13	926550.CLDAP_28540	5.902e-38	150.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158433_k127_3295019_3	469383.Cwoe_1145	1.76e-138	452.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CPM3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158433_k127_3295019_17	469383.Cwoe_1146	3.905e-25	117.0	COG2010@1|root,COG2010@2|Bacteria,2HQT0@201174|Actinobacteria,4CSHK@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158433_k127_3295019_12	1283299.AUKG01000003_gene307	2.692e-39	151.0	COG1853@1|root,COG1853@2|Bacteria,2HP7U@201174|Actinobacteria,4CRWN@84995|Rubrobacteria	84995|Rubrobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158433_k127_3295019_16	710685.MycrhN_4994	1.624e-29	122.0	2AJIH@1|root,31A5A@2|Bacteria,2IHK0@201174|Actinobacteria,239TW@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158433_k127_3295019_14	469383.Cwoe_1148	8.505e-34	135.0	2BGA2@1|root,32A7H@2|Bacteria,2HTT4@201174|Actinobacteria,4CT2Y@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3295019_15	1283299.AUKG01000003_gene305	1.32e-31	128.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CQ6Q@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158433_k127_3295019_8	1379698.RBG1_1C00001G1051	1.192e-55	205.0	COG0377@1|root,COG0377@2|Bacteria,2NP84@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158433_k127_3295019_10	469383.Cwoe_1151	2.424e-52	189.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CQ8D@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158433_k127_3295019_4	469383.Cwoe_1152	3.752e-98	326.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CP64@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158433_k127_3365950_4	1283299.AUKG01000002_gene4333	9.636e-19	100.0	2AWUM@1|root,31NRV@2|Bacteria,2HRAH@201174|Actinobacteria,4CT7D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3365950_1	1283299.AUKG01000002_gene4334	1.163e-149	494.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CSIF@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
SRR25158433_k127_3365950_0	1380390.JIAT01000010_gene3561	1.118e-187	593.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CRQG@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_2
SRR25158433_k127_3365950_5	573370.DMR_14340	1.897e-16	87.0	29XTP@1|root,30JJR@2|Bacteria,1QTBX@1224|Proteobacteria,436Y4@68525|delta/epsilon subdivisions,2X1NB@28221|Deltaproteobacteria,2MFCX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SRR25158433_k127_3365950_3	765914.ThisiDRAFT_2836	4.906e-22	97.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1WZ7T@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
SRR25158433_k127_3365950_2	1380390.JIAT01000009_gene361	5.86e-109	357.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4CSMA@84995|Rubrobacteria	84995|Rubrobacteria	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158433_k127_3396658_3	469383.Cwoe_3173	3.158e-60	211.0	COG0491@1|root,COG0491@2|Bacteria,2HGYI@201174|Actinobacteria,4CQY2@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_3396658_2	469383.Cwoe_3189	5.509e-107	355.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CR9C@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158433_k127_3396658_0	1283299.AUKG01000002_gene5232	0.0	1039.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158433_k127_3396658_1	469383.Cwoe_3186	5.912e-129	433.0	COG0608@1|root,COG0608@2|Bacteria,2IK2U@201174|Actinobacteria,4CPI9@84995|Rubrobacteria	84995|Rubrobacteria	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158433_k127_3400440_14	1279038.KB907343_gene2447	9.315e-11	66.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,2JSUG@204441|Rhodospirillales	204441|Rhodospirillales	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158433_k127_3400440_9	469383.Cwoe_2896	1.27e-40	167.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CQQP@84995|Rubrobacteria	84995|Rubrobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158433_k127_3400440_7	469383.Cwoe_2893	5.137e-79	269.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158433_k127_3400440_17	207559.Dde_1512	1.501e-08	58.0	2AX7C@1|root,31P63@2|Bacteria,1QKVB@1224|Proteobacteria,4370Q@68525|delta/epsilon subdivisions,2X1RG@28221|Deltaproteobacteria,2MFIF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158433_k127_3400440_4	1120950.KB892741_gene2626	4.944e-115	385.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4DNPX@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158433_k127_3400440_10	1380390.JIAT01000016_gene5542	7.964e-40	152.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4CSPV@84995|Rubrobacteria	84995|Rubrobacteria	H	Aspartate decarboxylase	-	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158433_k127_3400440_5	1120950.KB892741_gene2627	1.099e-101	341.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4DP0Z@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158433_k127_3400440_8	469383.Cwoe_2883	1.916e-70	243.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CS0J@84995|Rubrobacteria	84995|Rubrobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158433_k127_3400440_3	469383.Cwoe_3307	8.022e-125	412.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158433_k127_3400440_12	526225.Gobs_0797	1.443e-19	93.0	COG1848@1|root,COG1848@2|Bacteria,2GRA5@201174|Actinobacteria,4EVXY@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158433_k127_3400440_15	1146883.BLASA_0141	1.445e-10	65.0	COG4118@1|root,COG4118@2|Bacteria,2GZW9@201174|Actinobacteria,4EWJT@85013|Frankiales	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158433_k127_3400440_0	469383.Cwoe_5338	3.827e-137	447.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4CPF0@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SRR25158433_k127_3400440_6	469383.Cwoe_5339	2.422e-97	326.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	xylG	-	3.6.3.17	ko:K02056,ko:K10545	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4	-	-	ABC_tran
SRR25158433_k127_3400440_2	1122939.ATUD01000004_gene3895	4.379e-125	411.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4CP9G@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158433_k127_3400440_1	593750.Metfor_1586	1.476e-130	472.0	COG3391@1|root,COG5276@1|root,arCOG02560@2157|Archaea,arCOG02565@2157|Archaea,2Y1HK@28890|Euryarchaeota,2NA4J@224756|Methanomicrobia	224756|Methanomicrobia	S	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SRR25158433_k127_3400440_11	1121930.AQXG01000004_gene2868	2.14e-28	136.0	COG1572@1|root,COG2911@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG4733@2|Bacteria,4NYS6@976|Bacteroidetes,1IZ9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3400440_16	456442.Mboo_1601	4.445e-09	72.0	COG3291@1|root,COG3391@1|root,arCOG02510@2157|Archaea,arCOG03563@2157|Archaea	2157|Archaea	P	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,NHL,PKD
SRR25158433_k127_341606_3	1283299.AUKG01000002_gene4564	1.495e-23	109.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158433_k127_341606_0	469383.Cwoe_0775	1.946e-105	351.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CPZT@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
SRR25158433_k127_341606_1	105420.BBPO01000029_gene6753	4.331e-101	351.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,2NFQW@228398|Streptacidiphilus	201174|Actinobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158433_k127_341606_2	1380390.JIAT01000009_gene1555	1.23e-48	181.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4CQ70@84995|Rubrobacteria	84995|Rubrobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158433_k127_3446721_0	653045.Strvi_7997	0.0	1916.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_3475965_9	861299.J421_1255	4.326e-20	93.0	COG3795@1|root,COG3795@2|Bacteria,1ZUYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158433_k127_3475965_4	1303692.SFUL_2580	5.042e-95	338.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10234	ko02010,map02010	M00201,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158433_k127_3475965_0	469383.Cwoe_2937	3.186e-172	550.0	COG1175@1|root,COG1175@2|Bacteria,2GKYS@201174|Actinobacteria,4CRVK@84995|Rubrobacteria	84995|Rubrobacteria	G	SdrD B-like domain	-	-	-	ko:K10233	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1,SdrD_B
SRR25158433_k127_3475965_2	1380390.JIAT01000009_gene1537	2.181e-156	510.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria,4CS8Q@84995|Rubrobacteria	84995|Rubrobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158433_k127_3475965_1	469383.Cwoe_2935	1.745e-170	544.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158433_k127_3475965_5	1120947.ATUX01000005_gene1510	1.36e-94	324.0	COG3012@1|root,COG3012@2|Bacteria,2IGEK@201174|Actinobacteria	201174|Actinobacteria	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3475965_12	697282.Mettu_3821	7.056e-11	69.0	COG1724@1|root,COG1724@2|Bacteria,1NMBX@1224|Proteobacteria	1224|Proteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158433_k127_3475965_11	747365.Thena_0411	2.651e-13	72.0	COG1598@1|root,COG1598@2|Bacteria,1TUVH@1239|Firmicutes,25NCF@186801|Clostridia,42HI1@68295|Thermoanaerobacterales	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158433_k127_3475965_7	929712.KI912613_gene3706	1.68e-66	238.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4CQRB@84995|Rubrobacteria	84995|Rubrobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158433_k127_3475965_6	1380390.JIAT01000010_gene4052	3.132e-71	246.0	COG3932@1|root,COG3932@2|Bacteria,2H701@201174|Actinobacteria,4CRAU@84995|Rubrobacteria	84995|Rubrobacteria	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
SRR25158433_k127_3475965_10	479431.Namu_4411	1.855e-16	90.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria,4ETME@85013|Frankiales	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB2	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158433_k127_3475965_8	246196.MSMEI_2086	4.451e-28	120.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,2396M@1762|Mycobacteriaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158433_k127_3475965_3	1048339.KB913029_gene2507	1.048e-109	361.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU9G@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_3498100_12	861299.J421_3240	0.0008989	42.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158433_k127_3498100_3	744980.TRICHSKD4_3508	1.945e-51	204.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
SRR25158433_k127_3498100_6	1283299.AUKG01000001_gene2013	4.752e-48	176.0	COG2411@1|root,COG2411@2|Bacteria,2HNQQ@201174|Actinobacteria,4CPX9@84995|Rubrobacteria	84995|Rubrobacteria	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158433_k127_3498100_4	748280.NH8B_2023	8.635e-50	183.0	COG3832@1|root,COG3832@2|Bacteria,1RICZ@1224|Proteobacteria,2VTB3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158433_k127_3498100_8	469383.Cwoe_5811	2.732e-46	168.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CQN4@84995|Rubrobacteria	84995|Rubrobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158433_k127_3498100_0	1120950.KB892775_gene1166	3.079e-216	683.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNNQ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158433_k127_3498100_5	1283299.AUKG01000001_gene1940	8.436e-49	188.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158433_k127_3498100_2	1283299.AUKG01000001_gene1992	5.484e-95	321.0	COG0702@1|root,COG0702@2|Bacteria,2HM0H@201174|Actinobacteria,4CQ71@84995|Rubrobacteria	84995|Rubrobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158433_k127_3498100_7	469383.Cwoe_5818	1.728e-47	178.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4CQEK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158433_k127_3498100_10	1380390.JIAT01000017_gene5271	6.756e-14	78.0	2B3SP@1|root,31WGA@2|Bacteria,2HQUY@201174|Actinobacteria,4CSMU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_3498100_9	926560.KE387025_gene4073	1.352e-36	160.0	COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
SRR25158433_k127_3498100_11	105422.BBPM01000011_gene7176	0.000642	49.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,2NH27@228398|Streptacidiphilus	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158433_k127_3498100_1	1283299.AUKG01000001_gene1989	8.169e-154	496.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4CPSM@84995|Rubrobacteria	84995|Rubrobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158433_k127_389375_2	1283299.AUKG01000001_gene2914	2.261e-50	185.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
SRR25158433_k127_389375_3	1380390.JIAT01000011_gene2828	4.711e-33	145.0	2AUJS@1|root,31K8C@2|Bacteria,2HP69@201174|Actinobacteria,4CQI1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_389375_1	1122939.ATUD01000001_gene89	1.99e-50	196.0	COG0637@1|root,COG0637@2|Bacteria,2I7TC@201174|Actinobacteria,4CQ6H@84995|Rubrobacteria	84995|Rubrobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158433_k127_389375_0	469383.Cwoe_1664	1.057e-76	262.0	COG0846@1|root,COG0846@2|Bacteria,2IFPA@201174|Actinobacteria,4CQ9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158433_k127_404187_0	1003195.SCAT_1375	1.091e-83	292.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
SRR25158433_k127_404187_3	1008457.BAEX01000005_gene943	1.102e-06	55.0	COG1476@1|root,COG1476@2|Bacteria,4PN0C@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158433_k127_404187_1	1380390.JIAT01000010_gene4387	1.048e-59	218.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158433_k127_419765_3	929712.KI912613_gene1840	6.35e-31	133.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CQYD@84995|Rubrobacteria	84995|Rubrobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158433_k127_419765_4	469383.Cwoe_0801	2.072e-28	130.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CQCY@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158433_k127_419765_0	469383.Cwoe_0800	8.335e-129	421.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CPEG@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158433_k127_419765_2	469383.Cwoe_0799	5.546e-41	159.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CQBV@84995|Rubrobacteria	84995|Rubrobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158433_k127_419765_1	1380390.JIAT01000009_gene1510	1.525e-83	281.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CP69@84995|Rubrobacteria	84995|Rubrobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158433_k127_419774_5	469383.Cwoe_0789	4.396e-26	124.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2HPUE@201174|Actinobacteria,4CR88@84995|Rubrobacteria	84995|Rubrobacteria	M	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
SRR25158433_k127_419774_0	469383.Cwoe_0790	1.206e-196	620.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CQZJ@84995|Rubrobacteria	84995|Rubrobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158433_k127_419774_1	469383.Cwoe_0791	3.166e-85	287.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158433_k127_419774_4	469383.Cwoe_0792	7.568e-62	227.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4CRYZ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158433_k127_419774_2	469383.Cwoe_0795	2.234e-74	259.0	COG0596@1|root,COG0596@2|Bacteria,2HTV2@201174|Actinobacteria,4CTBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158433_k127_419774_3	1380390.JIAT01000009_gene1519	1.291e-67	237.0	COG0177@1|root,COG0177@2|Bacteria,2HPSY@201174|Actinobacteria,4CR6E@84995|Rubrobacteria	84995|Rubrobacteria	L	FES	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158433_k127_419774_7	1380390.JIAT01000010_gene3509	8.465e-08	64.0	COG2010@1|root,COG2010@2|Bacteria,2HQZ9@201174|Actinobacteria,4CSSG@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158433_k127_419774_6	1463841.JOIR01000038_gene3490	7.994e-09	61.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158433_k127_424684_0	653045.Strvi_7997	0.0	1321.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_432655_4	1380390.JIAT01000014_gene6234	9.981e-41	157.0	COG0791@1|root,COG0791@2|Bacteria,2HQTI@201174|Actinobacteria,4CSIU@84995|Rubrobacteria	84995|Rubrobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_432655_1	1380390.JIAT01000011_gene2578	4.878e-145	466.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158433_k127_432655_0	1380390.JIAT01000011_gene2577	5.438e-167	544.0	COG0687@1|root,COG0687@2|Bacteria	2|Bacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
SRR25158433_k127_432655_3	1394178.AWOO02000109_gene5733	7.371e-97	325.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4EHZ3@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
SRR25158433_k127_432655_2	1380390.JIAT01000011_gene2575	1.326e-103	342.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4CQ2P@84995|Rubrobacteria	201174|Actinobacteria	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158433_k127_441975_4	663610.JQKO01000001_gene989	1.468e-21	96.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,3N9PF@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
SRR25158433_k127_441975_1	671143.DAMO_1598	4.346e-92	324.0	COG1071@1|root,COG1071@2|Bacteria,2NQC2@2323|unclassified Bacteria	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158433_k127_441975_2	469383.Cwoe_4651	3.661e-54	196.0	COG3917@1|root,COG3917@2|Bacteria,2HPCS@201174|Actinobacteria,4CQQS@84995|Rubrobacteria	84995|Rubrobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158433_k127_441975_6	1070319.CAGGBEG34_270015	2.121e-07	61.0	COG4374@1|root,COG4374@2|Bacteria,1Q1CR@1224|Proteobacteria,2W6I6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_441975_0	1283299.AUKG01000001_gene1500	3.596e-143	467.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CPRJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158433_k127_441975_3	469383.Cwoe_2925	6.561e-31	140.0	COG5640@1|root,COG5640@2|Bacteria,2GN18@201174|Actinobacteria,4CTGT@84995|Rubrobacteria	84995|Rubrobacteria	M	SMART peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158433_k127_441975_5	469383.Cwoe_0769	4.788e-21	100.0	2B9V4@1|root,32383@2|Bacteria,2HRXS@201174|Actinobacteria,4CU12@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_454052_4	469383.Cwoe_3725	2.456e-10	70.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CQ89@84995|Rubrobacteria	84995|Rubrobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158433_k127_454052_1	1380390.JIAT01000010_gene4188	2.004e-53	198.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CQ1V@84995|Rubrobacteria	84995|Rubrobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158433_k127_454052_0	1283299.AUKG01000002_gene4666	5.256e-209	672.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4CPGM@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158433_k127_454052_3	469383.Cwoe_3728	2.044e-35	146.0	COG3428@1|root,COG3428@2|Bacteria,2HQX2@201174|Actinobacteria,4CSPP@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158433_k127_454052_2	469383.Cwoe_3729	2.103e-45	166.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CPIK@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158433_k127_470467_27	479434.Sthe_3510	4.052e-46	177.0	COG2141@1|root,COG2141@2|Bacteria,2GB9A@200795|Chloroflexi,27Y8J@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158433_k127_470467_2	469383.Cwoe_0782	6.087e-162	527.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CRR6@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158433_k127_470467_41	1380390.JIAT01000009_gene1544	1.188e-10	67.0	2AUQB@1|root,31KDA@2|Bacteria,2GX9T@201174|Actinobacteria,4CQM3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_470467_33	1283299.AUKG01000001_gene1490	4.01e-29	129.0	COG3021@1|root,COG3021@2|Bacteria,2HQIN@201174|Actinobacteria,4CS44@84995|Rubrobacteria	84995|Rubrobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158433_k127_470467_9	469383.Cwoe_0778	1.396e-99	334.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CPYJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158433_k127_470467_8	1283299.AUKG01000001_gene2396	2.28e-100	333.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CQIT@84995|Rubrobacteria	84995|Rubrobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158433_k127_470467_26	1283299.AUKG01000002_gene3862	1.566e-47	181.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158433_k127_470467_4	469383.Cwoe_1681	5.405e-137	452.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CR5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158433_k127_470467_6	1122939.ATUD01000001_gene386	1.007e-120	395.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CPWR@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158433_k127_470467_14	1122939.ATUD01000001_gene289	1.865e-69	244.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQ3X@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158433_k127_470467_46	1342302.JASC01000003_gene3595	1.607e-06	55.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	intD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0008979,GO:0009009,GO:0009987,GO:0015074,GO:0016032,GO:0019042,GO:0019043,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051704,GO:0071704,GO:0075713,GO:0090304,GO:0140097,GO:1901360	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	Phage_integrase
SRR25158433_k127_470467_16	866895.HBHAL_4692	1.213e-62	237.0	COG4938@1|root,COG4938@2|Bacteria,1V5VH@1239|Firmicutes,4IRV1@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3696)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
SRR25158433_k127_470467_22	1068980.ARVW01000001_gene4419	1.969e-54	195.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4E5EV@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158433_k127_470467_37	76114.ebD37	2.398e-13	76.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
SRR25158433_k127_470467_45	118166.JH976537_gene2237	6.053e-07	55.0	2EIPJ@1|root,33CEZ@2|Bacteria,1GAKK@1117|Cyanobacteria,1HDQM@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
SRR25158433_k127_470467_36	1123267.JONN01000001_gene2454	5.65e-14	83.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158433_k127_470467_0	1121924.ATWH01000014_gene3423	2.903e-256	817.0	COG1002@1|root,COG1002@2|Bacteria,2IA5I@201174|Actinobacteria,4FPDT@85023|Microbacteriaceae	201174|Actinobacteria	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158433_k127_470467_12	1352941.M877_36820	3.569e-75	256.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158433_k127_470467_40	766499.C357_19306	3.234e-11	73.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Membrane	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158433_k127_470467_50	1298920.KI911353_gene1234	0.0002372	48.0	2EFGV@1|root,3399G@2|Bacteria,1VHIS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_470467_44	640511.BC1002_4190	3.471e-07	57.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_19,HTH_3,HTH_31,TPR_12,TPR_16,TPR_8
SRR25158433_k127_470467_51	1123302.KB904159_gene1259	0.0005947	49.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	XK27_09155	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158433_k127_470467_13	1380390.JIAT01000010_gene3657	1.804e-73	255.0	COG4916@1|root,COG4916@2|Bacteria,2GQ7W@201174|Actinobacteria	201174|Actinobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1883,TIR_2
SRR25158433_k127_470467_1	1283299.AUKG01000001_gene1541	1.33e-182	602.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_470467_20	1283299.AUKG01000001_gene1540	2.903e-58	215.0	2DMG1@1|root,32RAP@2|Bacteria,2HVCN@201174|Actinobacteria	201174|Actinobacteria	S	Replication-relaxation	-	-	-	-	-	-	-	-	-	-	-	-	Replic_Relax
SRR25158433_k127_470467_3	1283299.AUKG01000001_gene1537	1.329e-137	451.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4CQMR@84995|Rubrobacteria	84995|Rubrobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158433_k127_470467_49	99598.Cal7507_4879	0.0001956	53.0	COG4691@1|root,COG4691@2|Bacteria,1GA88@1117|Cyanobacteria,1HPB7@1161|Nostocales	1117|Cyanobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	RHH_5
SRR25158433_k127_470467_39	1125863.JAFN01000001_gene638	2.381e-11	70.0	COG4113@1|root,COG4113@2|Bacteria,1N7ET@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158433_k127_470467_29	888052.HMPREF9006_1728	2.526e-41	172.0	COG0827@1|root,COG0827@2|Bacteria,2I8PF@201174|Actinobacteria,4D53A@85005|Actinomycetales	201174|Actinobacteria	L	N-6 DNA Methylase	xamIM	-	-	-	-	-	-	-	-	-	-	-	MTS,Met_10,N6_Mtase
SRR25158433_k127_470467_11	469383.Cwoe_3564	1.662e-81	280.0	COG3662@1|root,COG3662@2|Bacteria,2II6C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158433_k127_470467_7	78346.BRUM_0800	6.822e-112	380.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CZ6U@85004|Bifidobacteriales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158433_k127_470467_17	1380390.JIAT01000014_gene6051	1.885e-61	219.0	COG1716@1|root,COG2197@1|root,COG1716@2|Bacteria,COG2197@2|Bacteria,2IJPV@201174|Actinobacteria,4CR0J@84995|Rubrobacteria	84995|Rubrobacteria	KT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158433_k127_470467_15	469383.Cwoe_1050	9.827e-64	228.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4CQ3N@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_470467_48	1132442.KB889753_gene132	0.0001621	46.0	29S0J@1|root,30D4W@2|Bacteria,1UAUR@1239|Firmicutes,4IM7J@91061|Bacilli,1ZJEQ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_470467_31	1173028.ANKO01000015_gene4600	1.937e-32	132.0	COG0295@1|root,COG0295@2|Bacteria,1GAJC@1117|Cyanobacteria	1117|Cyanobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158433_k127_470467_18	546414.Deide_02070	1.854e-59	211.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_470467_24	35754.JNYJ01000014_gene4857	6.713e-51	188.0	COG1309@1|root,COG1309@2|Bacteria,2IKK0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_470467_25	258533.BN977_02690	1.291e-49	180.0	2DJ5J@1|root,32UCF@2|Bacteria,2II98@201174|Actinobacteria,2396N@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_470467_19	469383.Cwoe_3656	6.991e-59	213.0	COG0500@1|root,COG2226@2|Bacteria,2IREW@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158433_k127_470467_34	1283299.AUKG01000002_gene4563	6.809e-22	103.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sig20	-	-	ko:K02405,ko:K03088	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	AbfB,CAP,Glyco_hydro_cc,Sigma70_r2
SRR25158433_k127_470467_30	469383.Cwoe_3152	3.157e-37	148.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_470467_28	33876.JNXY01000001_gene5645	1.387e-42	166.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4DCQV@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_470467_32	469383.Cwoe_3152	4.506e-30	132.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158433_k127_470467_10	469383.Cwoe_0201	6.756e-99	336.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4CR0C@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158433_k127_470467_23	1380390.JIAT01000009_gene1288	1.573e-51	203.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4CRBY@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158433_k127_470467_21	469383.Cwoe_5518	4.838e-56	200.0	COG1528@1|root,COG1528@2|Bacteria,2IG5S@201174|Actinobacteria,4CU3R@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferritin-like domain	-	-	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158433_k127_470467_5	1283299.AUKG01000001_gene3048	8.695e-129	421.0	COG4948@1|root,COG4948@2|Bacteria,2I7AE@201174|Actinobacteria,4CPIJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_470467_43	478749.BRYFOR_09335	3.134e-08	60.0	290WP@1|root,2ZNIG@2|Bacteria,1W30M@1239|Firmicutes,255MG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_497588_1	1380390.JIAT01000009_gene1246	9.512e-66	231.0	COG0491@1|root,COG0491@2|Bacteria,2GSTF@201174|Actinobacteria,4CQ4G@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_497588_3	1380390.JIAT01000009_gene994	5.983e-49	178.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158433_k127_497588_0	1380390.JIAT01000009_gene993	4.131e-86	301.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4CSH9@84995|Rubrobacteria	84995|Rubrobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158433_k127_497588_2	929712.KI912613_gene4	2.647e-51	186.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4CQ59@84995|Rubrobacteria	84995|Rubrobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158433_k127_497588_5	1121121.KB894314_gene1544	8.9e-07	51.0	2EQ35@1|root,33HPH@2|Bacteria,1VMY6@1239|Firmicutes,4HRBN@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_497588_4	356851.JOAN01000022_gene2237	1.052e-25	124.0	299QG@1|root,2ZWSR@2|Bacteria,2H8TV@201174|Actinobacteria,4DK8J@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_498341_6	1246995.AFR_22385	3.396e-28	117.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158433_k127_498341_2	266117.Rxyl_0847	9.923e-103	368.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	84995|Rubrobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158433_k127_498341_3	266779.Meso_1873	3.019e-77	266.0	COG0428@1|root,COG0428@2|Bacteria,1QDFV@1224|Proteobacteria,2U492@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158433_k127_498341_0	644966.Tmar_0908	1.53e-167	557.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WCCQ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158433_k127_498341_4	1122939.ATUD01000003_gene3521	2.455e-76	263.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4CRXE@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158433_k127_498341_1	1122939.ATUD01000001_gene812	4.902e-136	452.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4CU6T@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158433_k127_498341_5	1380390.JIAT01000010_gene3918	4.153e-71	257.0	COG0446@1|root,COG0446@2|Bacteria,2HQQT@201174|Actinobacteria,4CSDR@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158433_k127_504202_26	469383.Cwoe_1343	1.938e-11	64.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CPEQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158433_k127_504202_19	1283299.AUKG01000001_gene2635	2.592e-38	147.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CQEC@84995|Rubrobacteria	84995|Rubrobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158433_k127_504202_20	1380390.JIAT01000011_gene2593	4.216e-33	139.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4CQP9@84995|Rubrobacteria	84995|Rubrobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158433_k127_504202_3	469383.Cwoe_1346	3.343e-106	351.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CPWK@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158433_k127_504202_11	469383.Cwoe_1347	3.448e-64	234.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4CQ15@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158433_k127_504202_24	469383.Cwoe_1348	5.727e-13	72.0	COG0255@1|root,COG0255@2|Bacteria,2HPC6@201174|Actinobacteria,4CQQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158433_k127_504202_21	1122939.ATUD01000003_gene3575	4.451e-30	128.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CQJP@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158433_k127_504202_12	469383.Cwoe_1350	1.02e-59	208.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CQ56@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158433_k127_504202_22	1380390.JIAT01000011_gene2599	1.231e-28	128.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4CQNC@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158433_k127_504202_8	469383.Cwoe_1352	1.998e-82	287.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158433_k127_504202_23	469383.Cwoe_1353	2.635e-22	102.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CQKA@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158433_k127_504202_18	1121934.AUDX01000003_gene980	9.608e-39	148.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4FNTW@85023|Microbacteriaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158433_k127_504202_9	1380390.JIAT01000011_gene2603	1.151e-76	267.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158433_k127_504202_17	469383.Cwoe_1356	1.71e-43	170.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4CQBN@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158433_k127_504202_10	1283299.AUKG01000001_gene2648	3.478e-74	263.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CPMN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158433_k127_504202_27	290317.Cpha266_2405	3.672e-10	62.0	COG1841@1|root,COG1841@2|Bacteria,1FE7E@1090|Chlorobi	1090|Chlorobi	J	PFAM ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158433_k127_504202_13	1380390.JIAT01000011_gene2607	3.791e-59	211.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158433_k127_504202_0	469383.Cwoe_1360	2.547e-202	645.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CPTT@84995|Rubrobacteria	84995|Rubrobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158433_k127_504202_7	469383.Cwoe_1361	2.735e-84	284.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CP9X@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158433_k127_504202_2	1380390.JIAT01000011_gene2610	7.966e-120	389.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CPA2@84995|Rubrobacteria	84995|Rubrobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158433_k127_504202_25	908337.HMPREF9257_0112	1.088e-11	74.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,27EZF@186827|Aerococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158433_k127_504202_16	1380390.JIAT01000011_gene2612	5.991e-51	183.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4CQ8S@84995|Rubrobacteria	84995|Rubrobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158433_k127_504202_14	469383.Cwoe_1365	4.468e-59	207.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4CPZ7@84995|Rubrobacteria	84995|Rubrobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158433_k127_504202_4	1283299.AUKG01000001_gene2657	5.205e-101	339.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CQ5S@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158433_k127_504202_1	469383.Cwoe_1366	2.56e-153	490.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158433_k127_504202_15	1283299.AUKG01000001_gene2659	5.652e-53	188.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CQ5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158433_k127_504202_6	469383.Cwoe_1368	2.798e-86	306.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CQ1A@84995|Rubrobacteria	84995|Rubrobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158433_k127_504202_5	266117.Rxyl_1173	2.009e-97	326.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158433_k127_526809_5	469383.Cwoe_3741	8.905e-15	76.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CPUN@84995|Rubrobacteria	84995|Rubrobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C
SRR25158433_k127_526809_0	1440774.Y900_023750	5.871e-186	594.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,2334D@1762|Mycobacteriaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158433_k127_526809_1	1041522.MCOL_V224317	9.81e-157	500.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,232XI@1762|Mycobacteriaceae	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd2	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1122	6PGD,NAD_binding_2
SRR25158433_k127_526809_3	404589.Anae109_0599	5.184e-54	198.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase	pgl	-	2.7.1.12,3.1.1.31	ko:K00851,ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R01737,R02035	RC00002,RC00017,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158433_k127_526809_6	1229780.BN381_430016	0.0002323	49.0	COG1396@1|root,COG1669@1|root,COG1396@2|Bacteria,COG1669@2|Bacteria,2GR6M@201174|Actinobacteria	201174|Actinobacteria	K	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,NTP_transf_2
SRR25158433_k127_526809_4	1048339.KB913029_gene4054	2.646e-43	164.0	2EE69@1|root,3380V@2|Bacteria,2GR09@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_526809_2	479431.Namu_2187	3.387e-76	261.0	COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158433_k127_56218_7	469383.Cwoe_3969	1.235e-96	334.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CPPE@84995|Rubrobacteria	201174|Actinobacteria	E	PFAM ABC transporter related	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158433_k127_56218_6	469383.Cwoe_4896	9.662e-106	349.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CPJW@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158433_k127_56218_3	469383.Cwoe_4897	2.934e-117	391.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158433_k127_56218_2	469383.Cwoe_3966	1.139e-125	410.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
SRR25158433_k127_56218_10	595460.RRSWK_00934	6.83e-64	224.0	COG2129@1|root,COG2129@2|Bacteria,2J1K1@203682|Planctomycetes	203682|Planctomycetes	S	Metallophosphoesterase, calcineurin superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158433_k127_56218_9	684949.ATTJ01000001_gene2129	2.233e-77	271.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lpsA1	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2
SRR25158433_k127_56218_12	68170.KL590503_gene268	1.298e-28	122.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,4E75F@85010|Pseudonocardiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158433_k127_56218_4	67257.JODR01000020_gene5381	3.512e-116	383.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria	201174|Actinobacteria	K	aldo keto reductase	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158433_k127_56218_1	929712.KI912613_gene2770	4.17e-134	456.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4CSJZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158433_k127_56218_8	1380390.JIAT01000009_gene1245	2.264e-93	335.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4CPAG@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158433_k127_56218_11	525368.HMPREF0591_3095	7.71e-33	132.0	COG3832@1|root,COG3832@2|Bacteria,2ISDQ@201174|Actinobacteria,23FFB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158433_k127_56218_14	446468.Ndas_2208	2.242e-13	80.0	COG0454@1|root,COG0456@2|Bacteria,2GP8I@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158433_k127_56218_5	469383.Cwoe_3526	3.137e-107	364.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158433_k127_56218_15	1463917.JODC01000014_gene1967	3.395e-09	68.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158433_k127_56218_0	469383.Cwoe_3741	3.164e-172	556.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CPUN@84995|Rubrobacteria	84995|Rubrobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C
SRR25158433_k127_56218_13	404589.Anae109_0597	5.955e-17	82.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N,Glyco_hydro_2
SRR25158433_k127_583425_8	469383.Cwoe_1889	2.693e-133	448.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CQTJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158433_k127_583425_13	1380390.JIAT01000014_gene6080	1.715e-103	366.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CP9P@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158433_k127_583425_27	1380390.JIAT01000014_gene6081	2.636e-31	128.0	COG0517@1|root,COG0517@2|Bacteria,2HPZ3@201174|Actinobacteria,4CREF@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158433_k127_583425_7	469383.Cwoe_1886	3.64e-143	469.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158433_k127_583425_10	211114.JOEF01000002_gene4590	8.503e-109	364.0	COG3177@1|root,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria,4E3SI@85010|Pseudonocardiales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158433_k127_583425_33	1210046.B277_05219	2.694e-05	57.0	2DKXG@1|root,30RUJ@2|Bacteria,2GM9V@201174|Actinobacteria,4FFXR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
SRR25158433_k127_583425_4	953739.SVEN_4418	1.976e-185	598.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158433_k127_583425_5	1380390.JIAT01000014_gene6085	1.304e-161	523.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CP8E@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158433_k127_583425_23	1380390.JIAT01000014_gene6086	1.04e-46	187.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CQGC@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158433_k127_583425_18	1380390.JIAT01000014_gene6087	2.326e-71	244.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CQAX@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158433_k127_583425_22	469383.Cwoe_1880	2.464e-50	191.0	COG0739@1|root,COG0739@2|Bacteria,2HP3A@201174|Actinobacteria,4CQEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M23
SRR25158433_k127_583425_25	469383.Cwoe_4742	4.072e-42	158.0	COG0735@1|root,COG0735@2|Bacteria,2HTHG@201174|Actinobacteria,4CSV2@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158433_k127_583425_26	1133849.O3I_039140	9.704e-37	152.0	COG0428@1|root,COG0428@2|Bacteria,2GSYE@201174|Actinobacteria,4FVY3@85025|Nocardiaceae	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158433_k127_583425_20	469383.Cwoe_5217	7.555e-57	209.0	2AUAR@1|root,31JYD@2|Bacteria,2HNZF@201174|Actinobacteria,4CQ8Y@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_583425_0	1283299.AUKG01000001_gene3191	1.577e-251	786.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CPPY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158433_k127_583425_3	469383.Cwoe_1874	2.986e-196	623.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CP9K@84995|Rubrobacteria	84995|Rubrobacteria	F	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158433_k127_583425_11	469383.Cwoe_1873	1.978e-108	360.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CQ17@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158433_k127_583425_19	469383.Cwoe_1872	2.024e-70	258.0	COG1686@1|root,COG1686@2|Bacteria,2GJ7C@201174|Actinobacteria,4CP6F@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158433_k127_583425_32	1122939.ATUD01000002_gene1273	5.802e-06	53.0	COG1388@1|root,COG1388@2|Bacteria,2HRID@201174|Actinobacteria,4CTIY@84995|Rubrobacteria	84995|Rubrobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158433_k127_583425_16	1283299.AUKG01000001_gene3186	8.869e-80	279.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CQ00@84995|Rubrobacteria	84995|Rubrobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158433_k127_583425_28	469383.Cwoe_1870	1.255e-26	112.0	COG0776@1|root,COG0776@2|Bacteria,2HN5N@201174|Actinobacteria,4CQJV@84995|Rubrobacteria	84995|Rubrobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158433_k127_583425_17	429009.Adeg_0661	3.971e-78	278.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158433_k127_583425_9	1229780.BN381_90073	2.175e-119	402.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158433_k127_583425_21	243164.DET0331	9.419e-57	213.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,34CPI@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158433_k127_583425_24	1122939.ATUD01000002_gene1269	1.557e-46	188.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CQ3I@84995|Rubrobacteria	84995|Rubrobacteria	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158433_k127_583425_12	469383.Cwoe_1866	7.509e-106	348.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158433_k127_583425_29	477974.Daud_2128	5.56e-15	84.0	COG2402@1|root,COG2402@2|Bacteria,1V8M3@1239|Firmicutes,24MAG@186801|Clostridia,2654W@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_583425_15	469383.Cwoe_1863	4.209e-96	325.0	COG0438@1|root,COG0438@2|Bacteria,2I8DC@201174|Actinobacteria,4CR51@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158433_k127_583425_6	1122939.ATUD01000002_gene1263	1.066e-146	486.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4CPRT@84995|Rubrobacteria	84995|Rubrobacteria	H	Glucose inhibited division protein A	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158433_k127_583425_2	469383.Cwoe_1857	2.267e-213	682.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158433_k127_583425_1	469383.Cwoe_1856	5.694e-219	690.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158433_k127_583425_14	469383.Cwoe_1855	9.018e-102	340.0	COG4293@1|root,COG4293@2|Bacteria,2IG98@201174|Actinobacteria,4CQEX@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158433_k127_59236_4	469383.Cwoe_4125	9.21e-133	428.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4CSSI@84995|Rubrobacteria	84995|Rubrobacteria	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158433_k127_59236_14	1283299.AUKG01000001_gene1940	4.228e-46	184.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158433_k127_59236_8	1298867.AUES01000006_gene363	2.049e-77	269.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,3JXVD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158433_k127_59236_12	929712.KI912613_gene762	1.122e-62	226.0	COG2085@1|root,COG2085@2|Bacteria,2I8W4@201174|Actinobacteria,4CQDF@84995|Rubrobacteria	84995|Rubrobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158433_k127_59236_10	1122939.ATUD01000012_gene3153	1.4e-73	268.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4CPHB@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158433_k127_59236_13	1380390.JIAT01000010_gene3612	1.531e-47	178.0	COG1920@1|root,COG1920@2|Bacteria,2HNVD@201174|Actinobacteria,4CQ43@84995|Rubrobacteria	84995|Rubrobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158433_k127_59236_9	469383.Cwoe_4151	5.641e-74	267.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158433_k127_59236_19	1380390.JIAT01000009_gene965	7.267e-09	59.0	COG3237@1|root,COG3237@2|Bacteria,2HPFB@201174|Actinobacteria,4CQTP@84995|Rubrobacteria	84995|Rubrobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158433_k127_59236_2	266117.Rxyl_0056	7.86e-153	489.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRR25158433_k127_59236_0	469383.Cwoe_4165	0.0	1110.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4CPHP@84995|Rubrobacteria	84995|Rubrobacteria	H	Elongator protein 3 MiaB NifB	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158433_k127_59236_17	1283299.AUKG01000001_gene1887	1.285e-42	166.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRR25158433_k127_59236_7	1380390.JIAT01000010_gene3607	1.2e-80	279.0	COG0715@1|root,COG0715@2|Bacteria,2HPRB@201174|Actinobacteria,4CR4H@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158433_k127_59236_16	1380390.JIAT01000010_gene3606	6.735e-44	164.0	2B8EI@1|root,321PH@2|Bacteria,2HP5J@201174|Actinobacteria,4CQHJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_59236_18	469383.Cwoe_4169	9.492e-13	74.0	2B8XJ@1|root,32280@2|Bacteria,2HRTD@201174|Actinobacteria,4CTWV@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_59236_15	469383.Cwoe_4172	2.171e-44	181.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158433_k127_59236_5	469383.Cwoe_2573	4.435e-117	404.0	COG0428@1|root,COG0428@2|Bacteria,2ICIQ@201174|Actinobacteria,4CSVK@84995|Rubrobacteria	84995|Rubrobacteria	P	Mediates zinc uptake. May also transport other divalent cations	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_59236_3	469383.Cwoe_2574	6.877e-138	449.0	COG2132@1|root,COG2132@2|Bacteria,2HPY5@201174|Actinobacteria,4CRDC@84995|Rubrobacteria	84995|Rubrobacteria	Q	PFAM multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158433_k127_59236_6	469383.Cwoe_4173	4.013e-81	281.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158433_k127_59236_20	469383.Cwoe_4175	2.056e-06	57.0	2A2E0@1|root,30QR0@2|Bacteria,2HRC5@201174|Actinobacteria,4CT9M@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_59236_11	1317118.ATO8_19704	6.942e-66	239.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,4KN4G@93682|Roseivivax	28211|Alphaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158433_k127_59236_1	469383.Cwoe_4182	4.919e-161	511.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CRE2@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158433_k127_604448_3	929712.KI912613_gene1159	6.963e-08	55.0	COG3307@1|root,COG3307@2|Bacteria,2IDMZ@201174|Actinobacteria,4CRI9@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158433_k127_604448_1	469383.Cwoe_0093	4.796e-105	359.0	COG2244@1|root,COG2244@2|Bacteria,2I9QU@201174|Actinobacteria,4CRDA@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158433_k127_604448_2	1380390.JIAT01000009_gene1694	7.461e-103	343.0	COG1216@1|root,COG1216@2|Bacteria,2HU9H@201174|Actinobacteria,4CPRC@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158433_k127_604448_0	469383.Cwoe_0095	3.961e-120	395.0	COG0438@1|root,COG0438@2|Bacteria,2GNPG@201174|Actinobacteria,4CRMS@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRR25158433_k127_636923_22	367299.JOEE01000003_gene2849	1.513e-06	55.0	2A5QH@1|root,30UFD@2|Bacteria,2HRWQ@201174|Actinobacteria,4FI46@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158433_k127_636923_17	469383.Cwoe_4539	4.594e-16	82.0	2BGGW@1|root,32AEX@2|Bacteria,2HPGT@201174|Actinobacteria,4CQV3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158433_k127_636923_5	469383.Cwoe_4537	1.453e-118	408.0	COG0741@1|root,COG1876@1|root,COG0741@2|Bacteria,COG1876@2|Bacteria,2I4JK@201174|Actinobacteria,4CQYM@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	SLT,VanY
SRR25158433_k127_636923_20	419947.MRA_2025	4.958e-13	82.0	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050896,GO:0065007,GO:0070482	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158433_k127_636923_12	526225.Gobs_1669	8.191e-33	131.0	COG1487@1|root,COG1487@2|Bacteria,2ISE2@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_636923_11	1380393.JHVP01000004_gene570	9.378e-43	161.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4ESRP@85013|Frankiales	201174|Actinobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158433_k127_636923_19	1380390.JIAT01000014_gene6069	5.392e-14	81.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria,2HSN9@201174|Actinobacteria,4CS57@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C
SRR25158433_k127_636923_14	469383.Cwoe_1897	1.195e-17	88.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	pbrT	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,Cytochrome_CBB3,FTR1
SRR25158433_k127_636923_10	66429.JOFL01000020_gene5559	4.467e-59	217.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1,SnoaL_2
SRR25158433_k127_636923_21	469383.Cwoe_3041	6.056e-09	69.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158433_k127_636923_0	469383.Cwoe_4536	5.121e-246	773.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CPMP@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158433_k127_636923_7	1380390.JIAT01000015_gene5677	2.815e-104	357.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CQY7@84995|Rubrobacteria	84995|Rubrobacteria	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_2
SRR25158433_k127_636923_18	595536.ADVE02000001_gene1182	1.4e-15	91.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1MU3S@1224|Proteobacteria,2U4GD@28211|Alphaproteobacteria,370TQ@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_S8
SRR25158433_k127_636923_6	1906.SFRA_18605	2.08e-107	355.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158433_k127_636923_9	981369.JQMJ01000004_gene5276	3.338e-61	234.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,2NJ3P@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158433_k127_636923_15	1429851.X548_11255	2.873e-16	83.0	COG0346@1|root,COG0346@2|Bacteria,1RH4D@1224|Proteobacteria,1S6J6@1236|Gammaproteobacteria,1XB7F@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158433_k127_636923_3	469383.Cwoe_4530	1.564e-153	491.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CPFY@84995|Rubrobacteria	84995|Rubrobacteria	G	Glyceraldehyde-3-phosphate dehydrogenase, type I	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158433_k127_636923_2	469383.Cwoe_4529	7.663e-163	522.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CPN6@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158433_k127_636923_8	469383.Cwoe_4528	2.462e-84	293.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CQ0V@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158433_k127_636923_1	469383.Cwoe_4527	2.842e-206	659.0	COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CR8U@84995|Rubrobacteria	84995|Rubrobacteria	G	BPG-independent PGAM N-terminus (iPGM_N)	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158433_k127_636923_23	246197.MXAN_4268	0.000959	47.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2Z0B0@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158433_k127_636923_4	1283299.AUKG01000002_gene4120	4.753e-148	479.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CPB3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158433_k127_636923_16	649638.Trad_1430	3.448e-16	83.0	2E3EN@1|root,32YDN@2|Bacteria,1WKIV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
SRR25158433_k127_636923_13	697282.Mettu_0806	9.525e-18	85.0	2E5P1@1|root,330DP@2|Bacteria,1N794@1224|Proteobacteria,1SD5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SRR25158433_k127_698132_3	216594.MMAR_2623	7.132e-84	286.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,236NE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158433_k127_698132_0	1298863.AUEP01000014_gene1712	0.0	1247.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DPP4@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158433_k127_698132_4	469383.Cwoe_1043	1.266e-08	61.0	2AXGF@1|root,31PG3@2|Bacteria,2HRV7@201174|Actinobacteria,4CTYJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_698132_1	562970.Btus_1382	2.021e-248	814.0	COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,279I7@186823|Alicyclobacillaceae	91061|Bacilli	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	odhA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158433_k127_698132_5	1299327.I546_3665	0.0001063	47.0	2CDGH@1|root,348SI@2|Bacteria,2GZQG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_698132_2	349521.HCH_04995	2.036e-159	511.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1XMDW@135619|Oceanospirillales	135619|Oceanospirillales	M	dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
SRR25158433_k127_709607_1	469383.Cwoe_2649	1.048e-102	337.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CPB5@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158433_k127_709607_0	469383.Cwoe_2652	0.0	1046.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CPR8@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158433_k127_747557_1	1283299.AUKG01000001_gene2557	1.322e-23	113.0	2DKYN@1|root,30WXH@2|Bacteria,2HQHS@201174|Actinobacteria,4CS33@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158433_k127_747557_0	1380390.JIAT01000009_gene1868	4.665e-170	558.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158433_k127_747557_3	1270196.JCKI01000007_gene2470	7.035e-15	83.0	COG0668@1|root,COG0668@2|Bacteria,4NFX6@976|Bacteroidetes,1IQV9@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158433_k127_747557_2	1380390.JIAT01000009_gene1872	1.923e-15	87.0	COG1266@1|root,COG1266@2|Bacteria,2HQBP@201174|Actinobacteria,4CRVX@84995|Rubrobacteria	84995|Rubrobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158433_k127_759785_3	1380390.JIAT01000009_gene1231	3.4e-56	200.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158433_k127_759785_1	469383.Cwoe_1095	4.78e-134	439.0	COG0524@1|root,COG0524@2|Bacteria,2HPJD@201174|Actinobacteria,4CQWU@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158433_k127_759785_2	105425.BBPL01000057_gene5466	9.588e-98	333.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,2NF1R@228398|Streptacidiphilus	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158433_k127_759785_0	1283299.AUKG01000003_gene218	2.076e-150	482.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CP81@84995|Rubrobacteria	84995|Rubrobacteria	L	DbpA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DbpA,Helicase_C
SRR25158433_k127_775214_0	1380390.JIAT01000011_gene2585	0.0	1028.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CPGY@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158433_k127_775214_1	1380390.JIAT01000011_gene2586	2.458e-226	704.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CPE9@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158433_k127_775214_4	469383.Cwoe_1339	9.532e-53	187.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4CQFD@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158433_k127_775214_3	1283299.AUKG01000001_gene2631	4.698e-86	290.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CPFD@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158433_k127_775214_5	469383.Cwoe_1341	9.087e-48	184.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CPXR@84995|Rubrobacteria	84995|Rubrobacteria	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158433_k127_775214_6	1283299.AUKG01000001_gene2633	1.251e-28	126.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4CQIU@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158433_k127_775214_2	469383.Cwoe_1343	1.35e-124	408.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CPEQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158433_k127_791951_3	489825.LYNGBM3L_21190	1.115e-134	435.0	COG0438@1|root,COG0438@2|Bacteria,1GC2Y@1117|Cyanobacteria	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_791951_2	489825.LYNGBM3L_21150	7.061e-138	454.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158433_k127_791951_7	5465.ENH85618	0.0008417	51.0	2EDN4@1|root,2RFHA@2759|Eukaryota,38N28@33154|Opisthokonta,3PPYK@4751|Fungi,3R236@4890|Ascomycota,21D78@147550|Sordariomycetes,1F6TX@1028384|Glomerellales	4751|Fungi	H	Phosphotransferase enzyme family protein	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158433_k127_791951_6	479435.Kfla_5520	5.431e-07	61.0	COG2334@1|root,COG2334@2|Bacteria,2H8XC@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158433_k127_791951_1	251229.Chro_0877	5.62e-199	672.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,3VINJ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158433_k127_791951_0	489825.LYNGBM3L_21220	1.096e-309	971.0	COG1216@1|root,COG5309@1|root,COG1216@2|Bacteria,COG5309@2|Bacteria,1G2MT@1117|Cyanobacteria,1H8YG@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
SRR25158433_k127_791951_5	1380390.JIAT01000010_gene3594	1.912e-07	61.0	2AWN7@1|root,31NIY@2|Bacteria,2HR42@201174|Actinobacteria,4CSZD@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_791951_4	469383.Cwoe_4182	5.221e-62	214.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CRE2@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158433_k127_819252_19	272943.RSP_1114	5.233e-14	83.0	COG2931@1|root,COG2931@2|Bacteria,1PEXW@1224|Proteobacteria,2V8V2@28211|Alphaproteobacteria,1FCXJ@1060|Rhodobacter	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158433_k127_819252_7	469383.Cwoe_3272	4.022e-97	328.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CPRV@84995|Rubrobacteria	84995|Rubrobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158433_k127_819252_12	469383.Cwoe_3271	2.089e-55	207.0	COG2227@1|root,COG2227@2|Bacteria,2I6IG@201174|Actinobacteria,4CQTF@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158433_k127_819252_3	469383.Cwoe_3270	9.921e-160	518.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CP8D@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158433_k127_819252_9	469383.Cwoe_3269	7.426e-76	271.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CQ16@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158433_k127_819252_20	582515.KR51_00031760	3.949e-13	78.0	COG0500@1|root,COG2226@2|Bacteria,1G0IS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
SRR25158433_k127_819252_13	1122939.ATUD01000005_gene2777	5.813e-52	193.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4CSZ5@84995|Rubrobacteria	84995|Rubrobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
SRR25158433_k127_819252_15	1348663.KCH_74080	4.785e-34	136.0	COG1225@1|root,COG1225@2|Bacteria,2IJVV@201174|Actinobacteria,2M2Y1@2063|Kitasatospora	201174|Actinobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158433_k127_819252_10	469383.Cwoe_3471	6.533e-73	261.0	COG1073@1|root,COG1073@2|Bacteria,2I3YE@201174|Actinobacteria,4CRF0@84995|Rubrobacteria	84995|Rubrobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158433_k127_819252_21	469383.Cwoe_0214	1.767e-11	74.0	2EAM3@1|root,31NNY@2|Bacteria,2HR7U@201174|Actinobacteria,4CT3W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_819252_18	1380390.JIAT01000009_gene1331	3.41e-20	98.0	COG4243@1|root,COG4243@2|Bacteria,2HGRK@201174|Actinobacteria,4CSQE@84995|Rubrobacteria	84995|Rubrobacteria	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158433_k127_819252_17	469383.Cwoe_5772	1.599e-31	136.0	COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria	201174|Actinobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158433_k127_819252_23	926566.Terro_4161	4.71e-05	53.0	COG4914@1|root,COG4914@2|Bacteria	926566.Terro_4161|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_819252_11	1206725.BAFU01000066_gene5664	9.197e-59	212.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4FUPK@85025|Nocardiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158433_k127_819252_5	469383.Cwoe_5919	1.827e-101	338.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4CQ02@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_819252_0	929712.KI912613_gene643	1.105e-205	645.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4CT0K@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158433_k127_819252_8	192952.MM_0249	5.427e-80	272.0	COG0655@1|root,arCOG02578@2157|Archaea,2Y5KU@28890|Euryarchaeota,2NBE4@224756|Methanomicrobia	224756|Methanomicrobia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158433_k127_819252_4	469383.Cwoe_1553	1.929e-106	351.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CQ2F@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158433_k127_819252_14	394221.Mmar10_0570	6.677e-39	155.0	COG3613@1|root,COG3613@2|Bacteria,1QZWH@1224|Proteobacteria	1224|Proteobacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_819252_22	1122939.ATUD01000007_gene2023	1.574e-05	53.0	COG0662@1|root,COG0662@2|Bacteria,2GZ5U@201174|Actinobacteria,4CSXN@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158433_k127_819252_6	469383.Cwoe_3476	4.506e-101	342.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CPGV@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family C-terminal domain	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
SRR25158433_k127_819252_2	469383.Cwoe_3478	9.439e-179	571.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158433_k127_819252_1	469383.Cwoe_3480	4.465e-181	595.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158433_k127_819252_16	469383.Cwoe_3484	8.776e-33	132.0	COG2050@1|root,COG2050@2|Bacteria,2HQVR@201174|Actinobacteria,4CSNV@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158433_k127_864323_5	1122939.ATUD01000014_gene1049	6.466e-29	117.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CP8W@84995|Rubrobacteria	84995|Rubrobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158433_k127_864323_2	469383.Cwoe_3708	1.848e-123	408.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4CQ5P@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158433_k127_864323_3	469383.Cwoe_3707	1.015e-59	213.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4CQB8@84995|Rubrobacteria	84995|Rubrobacteria	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158433_k127_864323_0	469383.Cwoe_3706	8.91e-232	725.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CPH5@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158433_k127_864323_4	1380390.JIAT01000010_gene4212	4.28e-50	183.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4CQNG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158433_k127_864323_6	1123024.AUII01000001_gene3028	1.166e-25	113.0	COG3744@1|root,COG3744@2|Bacteria,2GSS6@201174|Actinobacteria	201174|Actinobacteria	S	PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158433_k127_864323_8	1028800.RG540_CH00250	1.687e-17	85.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158433_k127_864323_7	469383.Cwoe_3704	7.051e-23	99.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4CQUE@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158433_k127_864323_1	469383.Cwoe_3703	1.031e-184	592.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CPUZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158433_k127_873561_5	469383.Cwoe_5942	9.61e-82	280.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CPD6@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158433_k127_873561_4	469383.Cwoe_5943	2.259e-102	341.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CQ24@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158433_k127_873561_10	469383.Cwoe_5944	1.327e-54	206.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CQFC@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158433_k127_873561_11	469383.Cwoe_5946	1.407e-41	158.0	COG1847@1|root,COG1847@2|Bacteria,2HPE2@201174|Actinobacteria,4CQS4@84995|Rubrobacteria	84995|Rubrobacteria	S	single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158433_k127_873561_9	1380390.JIAT01000009_gene1795	1.301e-55	203.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CPXT@84995|Rubrobacteria	84995|Rubrobacteria	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158433_k127_873561_13	1380390.JIAT01000009_gene1794	2.587e-30	123.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4CQSS@84995|Rubrobacteria	84995|Rubrobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158433_k127_873561_14	469383.Cwoe_5949	4.977e-30	126.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4CQCA@84995|Rubrobacteria	84995|Rubrobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158433_k127_873561_16	469383.Cwoe_5950	1.766e-10	65.0	COG0230@1|root,COG0230@2|Bacteria,2HH4A@201174|Actinobacteria,4CQS5@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158433_k127_873561_3	469383.Cwoe_0001	7.078e-118	396.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CPFC@84995|Rubrobacteria	84995|Rubrobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158433_k127_873561_2	469383.Cwoe_0002	8.204e-122	402.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CP8Y@84995|Rubrobacteria	84995|Rubrobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158433_k127_873561_7	1283299.AUKG01000001_gene1760	2.882e-76	269.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CQ4U@84995|Rubrobacteria	84995|Rubrobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
SRR25158433_k127_873561_15	469383.Cwoe_0004	2.004e-12	72.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158433_k127_873561_0	469383.Cwoe_0005	0.0	1073.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CP8I@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158433_k127_873561_1	469383.Cwoe_0006	0.0	1054.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CP85@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158433_k127_873561_8	469383.Cwoe_0007	1.789e-63	222.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CQBX@84995|Rubrobacteria	84995|Rubrobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158433_k127_873561_6	1380390.JIAT01000009_gene1785	7.429e-78	280.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CQFQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158433_k127_873561_12	1380390.JIAT01000009_gene1783	1.609e-30	130.0	2AVPF@1|root,31MGI@2|Bacteria,2HE2U@201174|Actinobacteria,4CQ1U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_877115_2	469383.Cwoe_5413	6.627e-166	539.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4CRNG@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158433_k127_877115_8	469383.Cwoe_3488	3.157e-27	119.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR25158433_k127_877115_3	469383.Cwoe_3490	1.281e-81	290.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CPZY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158433_k127_877115_5	1380390.JIAT01000010_gene4569	6.412e-68	233.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4CQ8I@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158433_k127_877115_7	1283299.AUKG01000002_gene4958	2.716e-27	114.0	2AUU1@1|root,31KH5@2|Bacteria,2HPC3@201174|Actinobacteria,4CQQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_877115_4	469383.Cwoe_3493	8.131e-70	245.0	COG0558@1|root,COG0558@2|Bacteria,2HGA5@201174|Actinobacteria,4CR84@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158433_k127_877115_0	469383.Cwoe_3494	2.543e-237	747.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158433_k127_877115_1	469383.Cwoe_3497	2.396e-211	663.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CP63@84995|Rubrobacteria	84995|Rubrobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158433_k127_877115_6	1300345.LF41_1325	2.377e-27	123.0	COG2931@1|root,COG2931@2|Bacteria,1R30G@1224|Proteobacteria,1T60T@1236|Gammaproteobacteria,1XDH4@135614|Xanthomonadales	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.4.24.40	ko:K01406,ko:K07004	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,VCBS
SRR25158433_k127_877115_9	525904.Tter_2098	0.0002232	52.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR25158433_k127_878752_1	105420.BBPO01000115_gene4275	3.086e-255	806.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,2NGDA@228398|Streptacidiphilus	201174|Actinobacteria	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158433_k127_878752_0	1463825.JNXC01000057_gene6352	0.0	1157.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4E898@85010|Pseudonocardiales	201174|Actinobacteria	Q	Enoylreductase	-	-	-	ko:K12436	-	-	-	-	ko00000,ko01004	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158433_k127_899865_1	1380390.JIAT01000009_gene2027	4.891e-116	387.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CPQ8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158433_k127_899865_2	1283299.AUKG01000001_gene1437	1.078e-114	376.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CPBJ@84995|Rubrobacteria	84995|Rubrobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158433_k127_899865_4	469383.Cwoe_0820	1.05e-24	114.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR25158433_k127_899865_3	469383.Cwoe_0821	1.823e-81	283.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4CPW1@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158433_k127_899865_0	1380390.JIAT01000009_gene1483	9.111e-274	864.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4CP9W@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158433_k127_899865_5	1206101.AZXC01000009_gene448	2.333e-20	96.0	2EVKU@1|root,33P0V@2|Bacteria,2IQJK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_913106_4	1122939.ATUD01000016_gene1843	1.372e-19	94.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_913106_1	1283299.AUKG01000002_gene3795	3.087e-148	477.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4CP76@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158433_k127_913106_0	469383.Cwoe_4683	1.13e-193	608.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158433_k127_913106_2	469383.Cwoe_5841	4.115e-80	276.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB,cNMP_binding
SRR25158433_k127_913106_6	158500.BV97_05172	5.427e-05	55.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,2UCP4@28211|Alphaproteobacteria,2K6AV@204457|Sphingomonadales	204457|Sphingomonadales	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158433_k127_913106_3	1380390.JIAT01000017_gene5300	2.09e-23	106.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4CPMS@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158433_k127_952359_1	1283299.AUKG01000001_gene2083	9.792e-37	149.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_952359_0	929712.KI912613_gene1183	1.598e-114	380.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CPIY@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158433_k127_952359_2	1122138.AQUZ01000008_gene3774	3.195e-30	138.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DP70@85009|Propionibacteriales	201174|Actinobacteria	P	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158433_k127_952359_3	469383.Cwoe_1805	2.221e-15	85.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4CPD7@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158433_k127_987599_2	1283299.AUKG01000002_gene4969	2.64e-19	94.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CQFM@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1
SRR25158433_k127_987599_3	74547.PMT_2851	1.503e-06	55.0	2DSJE@1|root,33GEB@2|Bacteria,1GB2T@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158433_k127_987599_1	1464048.JNZS01000013_gene3144	7.596e-83	284.0	COG0300@1|root,COG0300@2|Bacteria,2I2VP@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158433_k127_987599_0	1283299.AUKG01000002_gene4280	2.805e-87	292.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CQK7@84995|Rubrobacteria	84995|Rubrobacteria	K	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
## 2255 queries scanned
## Total time (seconds): 3.5530505180358887
## Rate: 634.67 q/s