## Mon Dec 15 15:03:34 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158456_bin.3.fa -m mmseqs --itype genome -o SRR25158456_bin.3 --output_dir /data/result/bins/wyx/egg/SRR25158456_bin.3 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158456_k127_1002287_12	234267.Acid_6263	1.146e-18	91.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_1002287_1	234267.Acid_7663	8.131e-139	454.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158456_k127_1002287_10	237368.SCABRO_03600	2.56e-28	122.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1002287_6	1205680.CAKO01000006_gene3405	6.336e-50	194.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158456_k127_1002287_7	1502850.FG91_01129	1.023e-47	184.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158456_k127_1002287_3	1242864.D187_004101	2.216e-89	308.0	COG4422@1|root,COG4422@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR25158456_k127_1002287_2	1242864.D187_000285	2.069e-115	377.0	COG4422@1|root,COG4422@2|Bacteria,1MXQI@1224|Proteobacteria,42NZ6@68525|delta/epsilon subdivisions,2WKPZ@28221|Deltaproteobacteria,2YWD6@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Gp37_Gp68	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SRR25158456_k127_1002287_11	391937.NA2_06837	7.207e-23	102.0	COG5470@1|root,COG5470@2|Bacteria,1PJHZ@1224|Proteobacteria,2UDNK@28211|Alphaproteobacteria,43QKC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158456_k127_1002287_9	1347368.HG964406_gene6385	1.346e-30	132.0	COG0454@1|root,COG0456@2|Bacteria,1TYX1@1239|Firmicutes,4IRK4@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158456_k127_1002287_14	246197.MXAN_3811	9.147e-10	65.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_1002287_0	1173027.Mic7113_3985	2.474e-164	552.0	COG0642@1|root,COG0745@1|root,COG2172@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,COG2205@2|Bacteria,1G2CJ@1117|Cyanobacteria,1H91Z@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_1002287_4	63737.Npun_R2264	4.181e-74	266.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,1G02S@1117|Cyanobacteria,1HRGU@1161|Nostocales	1117|Cyanobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE
SRR25158456_k127_1002287_5	886293.Sinac_0763	4.839e-53	190.0	COG2172@1|root,COG2172@2|Bacteria,2J3C4@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c
SRR25158456_k127_1002287_8	1097668.BYI23_B015180	2.144e-41	154.0	COG1366@1|root,COG1366@2|Bacteria,1RJM8@1224|Proteobacteria,2VT28@28216|Betaproteobacteria,1K7XA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158456_k127_1012465_3	1047013.AQSP01000042_gene408	2.691e-16	89.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
SRR25158456_k127_1012465_4	1291050.JAGE01000001_gene3033	7.164e-16	87.0	2EC4I@1|root,3363E@2|Bacteria,1VJH4@1239|Firmicutes,25E22@186801|Clostridia	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158456_k127_1012465_1	1047013.AQSP01000138_gene1053	1.033e-65	245.0	COG1538@1|root,COG1538@2|Bacteria,2NP5D@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR25158456_k127_1012465_2	404589.Anae109_0057	2.998e-62	226.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria	1224|Proteobacteria	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
SRR25158456_k127_1012465_0	1266925.JHVX01000002_gene894	4.501e-246	771.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,372CG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
SRR25158456_k127_1027349_2	204669.Acid345_2913	4.307e-179	571.0	COG4805@1|root,COG4805@2|Bacteria,3Y3QB@57723|Acidobacteria,2JINM@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158456_k127_1027349_5	266117.Rxyl_1786	2.787e-54	202.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria,4CPW5@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158456_k127_1027349_11	1499967.BAYZ01000015_gene6576	1.587e-27	126.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	MA20_35625	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Peripla_BP_3
SRR25158456_k127_1027349_14	1454004.AW11_02453	2.955e-11	69.0	COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_1027349_9	1452718.JBOY01000073_gene3034	1.539e-44	172.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
SRR25158456_k127_1027349_15	448385.sce4243	4.148e-10	69.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria,439MQ@68525|delta/epsilon subdivisions,2X4YU@28221|Deltaproteobacteria,2YZV4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1027349_10	272123.Anacy_0358	6.718e-30	126.0	COG0400@1|root,COG0400@2|Bacteria,1G525@1117|Cyanobacteria,1HKIK@1161|Nostocales	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	sll1284	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158456_k127_1027349_3	903818.KI912268_gene1402	5.265e-167	533.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158456_k127_1027349_13	337191.KTR9_2120	1.55e-18	92.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4GDZ7@85026|Gordoniaceae	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158456_k127_1027349_7	1121930.AQXG01000003_gene2458	4.143e-49	189.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
SRR25158456_k127_1027349_0	1278073.MYSTI_06394	1.975e-263	838.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2YU3X@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158456_k127_1027349_6	1381751.JAJB01000043_gene3117	1.675e-49	194.0	COG0747@1|root,COG1345@1|root,COG3291@1|root,COG0747@2|Bacteria,COG1345@2|Bacteria,COG3291@2|Bacteria,2IRZH@201174|Actinobacteria	201174|Actinobacteria	O	negative chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,SLH
SRR25158456_k127_1027349_17	234267.Acid_4174	0.000607	47.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1027349_16	998674.ATTE01000001_gene3953	3.086e-05	51.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria,1SBYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1027349_12	246197.MXAN_1461	1.979e-26	111.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
SRR25158456_k127_1027349_1	204669.Acid345_1454	1.423e-226	715.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria,2JHJN@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158456_k127_1027349_4	234267.Acid_5065	1.812e-149	502.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria	57723|Acidobacteria	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158456_k127_1034242_17	1499967.BAYZ01000075_gene2072	4.262e-11	71.0	COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158456_k127_1034242_16	46234.ANA_C10943	3.228e-15	86.0	COG4640@1|root,COG4640@2|Bacteria,1G9F8@1117|Cyanobacteria	1117|Cyanobacteria	S	Interferon-induced transmembrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CD225
SRR25158456_k127_1034242_14	1121013.P873_12195	7.932e-26	111.0	COG4640@1|root,COG4640@2|Bacteria,1P7UN@1224|Proteobacteria,1TBJT@1236|Gammaproteobacteria,1X8N5@135614|Xanthomonadales	135614|Xanthomonadales	S	Interferon-induced transmembrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CD225
SRR25158456_k127_1034242_15	306281.AJLK01000156_gene4639	1.091e-19	93.0	2E37T@1|root,32Y7G@2|Bacteria,1GECJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SRR25158456_k127_1034242_18	1220589.CD32_05450	1.086e-06	54.0	COG2314@1|root,COG2314@2|Bacteria,1VCD2@1239|Firmicutes,4HWZD@91061|Bacilli,3IYPJ@400634|Lysinibacillus	91061|Bacilli	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158456_k127_1034242_20	1267533.KB906737_gene1973	2.535e-05	57.0	COG4818@1|root,COG4818@2|Bacteria	2|Bacteria	S	TM2 domain	M1-746	-	-	-	-	-	-	-	-	-	-	-	DUF4870
SRR25158456_k127_1034242_9	1499967.BAYZ01000004_gene4922	4.874e-57	222.0	28M0D@1|root,2ZAFE@2|Bacteria	2|Bacteria	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
SRR25158456_k127_1034242_2	1111479.AXAR01000008_gene2278	9.562e-99	334.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli	91061|Bacilli	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158456_k127_1034242_5	903818.KI912268_gene1552	1.49e-75	273.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158456_k127_1034242_10	1144275.COCOR_05402	6.409e-49	183.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2YVJK@29|Myxococcales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158456_k127_1034242_3	234267.Acid_1043	1.022e-92	320.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158456_k127_1034242_4	204669.Acid345_3271	7.271e-77	284.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158456_k127_1034242_12	1280390.CBQR020000166_gene4410	8.258e-40	156.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,26WV5@186822|Paenibacillaceae	91061|Bacilli	G	Aldolase	kdgA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158456_k127_1034242_6	717774.Marme_0882	7.188e-69	246.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1XHYC@135619|Oceanospirillales	135619|Oceanospirillales	L	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158456_k127_1034242_1	861299.J421_4299	6.032e-104	347.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_1034242_7	1121447.JONL01000009_gene2598	5.019e-65	235.0	COG0332@1|root,COG0332@2|Bacteria,1R8TJ@1224|Proteobacteria,4315V@68525|delta/epsilon subdivisions,2WWUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C
SRR25158456_k127_1034242_11	194439.CT1987	2.577e-46	181.0	COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158456_k127_1034242_0	1379698.RBG1_1C00001G0607	9.586e-167	550.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158456_k127_1034242_8	903818.KI912268_gene3365	1.596e-60	221.0	COG1100@1|root,COG1100@2|Bacteria,3Y7CQ@57723|Acidobacteria	57723|Acidobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
SRR25158456_k127_1034242_13	997346.HMPREF9374_3566	2.779e-38	151.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,27BS9@186824|Thermoactinomycetaceae	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158456_k127_1034569_0	525904.Tter_2125	0.0	1179.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2NQGX@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158456_k127_1034569_4	1123276.KB893258_gene2892	2.719e-42	159.0	COG4244@1|root,COG4244@2|Bacteria,4NPHV@976|Bacteroidetes,47PWW@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158456_k127_1034569_8	449447.MAE_44440	2.194e-24	108.0	COG3729@1|root,COG3729@2|Bacteria,1G86R@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Stress-induced bacterial acidophilic repeat motif	-	-	-	ko:K06884	-	-	-	-	ko00000	-	-	-	KGG
SRR25158456_k127_1034569_1	1144275.COCOR_01562	5.195e-131	434.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1MVRR@1224|Proteobacteria,42NSC@68525|delta/epsilon subdivisions,2WMAX@28221|Deltaproteobacteria,2YUKT@29|Myxococcales	28221|Deltaproteobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
SRR25158456_k127_1034569_3	1128421.JAGA01000003_gene3492	3.196e-98	334.0	COG0604@1|root,COG0604@2|Bacteria,2NQR7@2323|unclassified Bacteria	2|Bacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158456_k127_1034569_6	935557.ATYB01000009_gene966	9.842e-38	143.0	COG0640@1|root,COG0640@2|Bacteria,1N8QA@1224|Proteobacteria,2UC02@28211|Alphaproteobacteria,4BFCP@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	ybzH	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158456_k127_1034569_2	886293.Sinac_4341	5e-127	413.0	COG1171@1|root,COG1171@2|Bacteria,2IYNJ@203682|Planctomycetes	203682|Planctomycetes	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_1034569_5	987059.RBXJA2T_18218	1.431e-41	169.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2VQ5D@28216|Betaproteobacteria,1KKJT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	tdcF2	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158456_k127_1034569_7	478741.JAFS01000002_gene1035	8.755e-29	123.0	COG3744@1|root,COG3744@2|Bacteria,46T9X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1034569_9	592015.HMPREF1705_00555	2.226e-18	87.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_1037571_3	443255.SCLAV_p0535	4.86e-37	143.0	2F3XQ@1|root,33WPT@2|Bacteria	2|Bacteria	S	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158456_k127_1037571_4	1120917.AQXM01000051_gene292	3.078e-28	127.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,1WARJ@1268|Micrococcaceae	201174|Actinobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158456_k127_1037571_0	1237149.C900_03217	2.207e-195	621.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158456_k127_1037571_2	483219.LILAB_23700	2.172e-80	284.0	28HUE@1|root,2Z815@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1037571_1	762376.AXYL_02641	1.031e-116	402.0	COG3384@1|root,COG3384@2|Bacteria,1PUF4@1224|Proteobacteria,2VZW8@28216|Betaproteobacteria,3T6P8@506|Alcaligenaceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.74,1.13.11.76	ko:K15059	ko00627,ko01120,map00627,map01120	-	R05405	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158456_k127_1037571_5	251229.Chro_0960	5.313e-14	75.0	2CCSR@1|root,32RWC@2|Bacteria,1G749@1117|Cyanobacteria,3VMR6@52604|Pleurocapsales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158456_k127_1040948_3	861299.J421_1335	2.365e-57	220.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HD_5,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_1040948_2	861299.J421_1336	5.839e-126	414.0	COG0596@1|root,COG0596@2|Bacteria,1ZUIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	-	ko:K19707	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_6
SRR25158456_k127_1040948_4	378806.STAUR_1559	1.657e-15	79.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,42NKV@68525|delta/epsilon subdivisions,2WKPA@28221|Deltaproteobacteria,2YYW9@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158456_k127_1040948_0	1123257.AUFV01000020_gene2090	5.886e-171	541.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,1RNJH@1236|Gammaproteobacteria,1X4KZ@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158456_k127_1040948_1	84531.JMTZ01000095_gene445	9.679e-163	520.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,1RNB4@1236|Gammaproteobacteria,1X3BR@135614|Xanthomonadales	135614|Xanthomonadales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158456_k127_1044674_0	1123248.KB893316_gene4600	1.551e-138	476.0	COG1749@1|root,COG3055@1|root,COG1749@2|Bacteria,COG3055@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
SRR25158456_k127_1044674_1	1267535.KB906767_gene1739	1.614e-83	310.0	COG1075@1|root,COG1749@1|root,COG1075@2|Bacteria,COG1749@2|Bacteria	2|Bacteria	N	bacterial-type flagellum-dependent cell motility	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4082,Flagellin_N,Flg_bb_rod,Flg_bbr_C
SRR25158456_k127_1044674_6	172045.KS04_00940	0.0003948	51.0	COG3184@1|root,COG3184@2|Bacteria,4NSCK@976|Bacteroidetes,1I5E8@117743|Flavobacteriia,34RDM@308865|Elizabethkingia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
SRR25158456_k127_1044674_3	1120999.JONM01000024_gene3083	6.783e-29	117.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,2VVQD@28216|Betaproteobacteria,2KTES@206351|Neisseriales	206351|Neisseriales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1044674_2	1380350.JIAP01000010_gene5907	2.599e-58	207.0	COG3744@1|root,COG3744@2|Bacteria,1N2T0@1224|Proteobacteria,2UC39@28211|Alphaproteobacteria,43KZV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1044674_5	349521.HCH_05556	8.762e-06	55.0	2DH1U@1|root,2ZY3B@2|Bacteria,1P4AC@1224|Proteobacteria,1STFQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1047390_1	316056.RPC_1792	1.019e-127	430.0	COG1404@1|root,COG1404@2|Bacteria,1R5Y1@1224|Proteobacteria,2U1X6@28211|Alphaproteobacteria,3K1XU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158456_k127_1047390_7	671143.DAMO_0643	1.406e-22	103.0	COG5304@1|root,COG5304@2|Bacteria,2NRFS@2323|unclassified Bacteria	2|Bacteria	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
SRR25158456_k127_1047390_8	1249627.D779_0981	2.792e-17	92.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1WYZ4@135613|Chromatiales	135613|Chromatiales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
SRR25158456_k127_1047390_5	1379270.AUXF01000002_gene1339	2.661e-32	133.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	hyaE	GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277	-	ko:K03619,ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	HyaE,SCO1-SenC
SRR25158456_k127_1047390_6	35128.Thaps23419	1.585e-27	132.0	2BP9V@1|root,2S1RF@2759|Eukaryota,2XBPA@2836|Bacillariophyta	2836|Bacillariophyta	O	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6,SdrD_B
SRR25158456_k127_1047390_4	243231.GSU1945	3.933e-49	203.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1Q4PP@1224|Proteobacteria,42YRG@68525|delta/epsilon subdivisions,2WUJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
SRR25158456_k127_1047390_3	1429916.X566_21810	5.811e-56	210.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,2UB9Y@28211|Alphaproteobacteria,3JXKA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158456_k127_1047390_2	557598.LHK_03116	7.723e-57	207.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,2KRD6@206351|Neisseriales	206351|Neisseriales	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158456_k127_1047390_0	1125971.ASJB01000065_gene6264	4.658e-234	730.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4DXII@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM Dihydrolipoamide dehydrogenase	lpd	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158456_k127_1048545_0	1120999.JONM01000033_gene447	0.0	2267.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KQ86@206351|Neisseriales	206351|Neisseriales	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_1054798_0	927677.ALVU02000001_gene3052	3.626e-88	310.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	2.3.1.43	ko:K00650	ko00564,ko04979,map00564,map04979	-	R02114	RC00037,RC00055	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_6,DUF900,LCAT
SRR25158456_k127_1054798_1	927677.ALVU02000001_gene3056	2.715e-70	263.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Beta_helix,DUF1573,DUF4861,Pec_lyase_C,Pectinesterase
SRR25158456_k127_1057134_1	1121007.AUML01000030_gene133	2.064e-196	694.0	COG0454@1|root,COG3321@1|root,COG0456@2|Bacteria,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia,2YHN1@290174|Aquimarina	976|Bacteroidetes	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_1057134_0	1500893.JQNB01000001_gene2575	0.0	2651.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158456_k127_1058177_6	1379698.RBG1_1C00001G1750	1.972e-30	134.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158456_k127_1058177_7	321332.CYB_0347	2.701e-10	72.0	COG2199@1|root,COG3706@2|Bacteria,1GDIS@1117|Cyanobacteria,1H44M@1129|Synechococcus	1117|Cyanobacteria	T	GGDEF FHA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
SRR25158456_k127_1058177_1	335543.Sfum_1424	2.711e-162	523.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MQ90@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
SRR25158456_k127_1058177_5	290397.Adeh_3524	5.272e-67	249.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
SRR25158456_k127_1058177_8	237368.SCABRO_01095	7.776e-07	63.0	COG0457@1|root,COG0457@2|Bacteria	237368.SCABRO_01095|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1058177_2	1379698.RBG1_1C00001G1660	1.176e-119	395.0	COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
SRR25158456_k127_1058177_4	1183438.GKIL_2517	1.249e-95	327.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_1058177_3	234267.Acid_6481	6.766e-101	356.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_1058177_0	251221.35211765	6.974e-192	626.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_106045_1	1237149.C900_01928	5.944e-53	193.0	COG3321@1|root,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,47XYI@768503|Cytophagia	976|Bacteroidetes	Q	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_106045_0	555779.Dthio_PD3715	2.57e-131	430.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MAH6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158456_k127_106045_5	264462.Bd2202	3.515e-05	52.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
SRR25158456_k127_106045_3	1121920.AUAU01000002_gene2020	3.17e-10	64.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	spxA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1,1.97.1.4,3.2.2.24	ko:K00537,ko:K04069,ko:K05521,ko:K16509	-	-	R04710	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
SRR25158456_k127_106045_2	357808.RoseRS_4060	3.85e-25	123.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_1068805_2	1198452.Jab_2c06930	1.116e-83	293.0	COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,2WCJX@28216|Betaproteobacteria,477TJ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	homolog of phage Mu protein gp47	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1068805_4	266835.14026231	1.361e-59	224.0	COG3628@1|root,COG3628@2|Bacteria,1N23A@1224|Proteobacteria,2UER5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage baseplate assembly protein W	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
SRR25158456_k127_1068805_5	1112214.AHIS01000001_gene1743	1.257e-46	169.0	COG4104@1|root,COG4104@2|Bacteria,1Q174@1224|Proteobacteria,2UFRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
SRR25158456_k127_1068805_1	266835.14026229	1.87e-97	333.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2UDMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Rhs Element Vgr Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1068805_0	266835.14026228	3.475e-164	528.0	COG3500@1|root,COG3500@2|Bacteria,1R67C@1224|Proteobacteria,2U3GW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage protein D	-	-	-	ko:K06905	-	-	-	-	ko00000	-	-	-	Phage_GPD
SRR25158456_k127_1068805_3	1112214.AHIS01000001_gene1740	1.556e-63	226.0	COG1652@1|root,COG1652@2|Bacteria,1RG4I@1224|Proteobacteria,2U847@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1072940_0	745411.B3C1_00330	0.0	1320.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J58S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Protein export membrane protein	mexF	-	-	ko:K18299	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.16	-	-	ACR_tran
SRR25158456_k127_1072940_3	1116472.MGMO_172c00060	1.063e-17	86.0	COG5450@1|root,COG5450@2|Bacteria,1QN0B@1224|Proteobacteria,1SHDA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158456_k127_1072940_2	395961.Cyan7425_1159	5.361e-44	167.0	COG1487@1|root,COG1487@2|Bacteria,1G5YM@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1072940_1	861299.J421_5806	1.201e-88	321.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GUN4,GUN4_N,Peptidase_C13,Peptidase_C14,TPR_10
SRR25158456_k127_1072940_4	1304874.JAFY01000002_gene204	8.379e-09	69.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_4,TPR_8
SRR25158456_k127_107646_5	290397.Adeh_0651	1.815e-50	206.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
SRR25158456_k127_107646_7	1157490.EL26_06375	5.57e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,278K5@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_107646_12	452637.Oter_1726	1.17e-11	75.0	COG0265@1|root,COG0265@2|Bacteria,46UW8@74201|Verrucomicrobia,3K7DR@414999|Opitutae	2|Bacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158456_k127_107646_6	498761.HM1_0203	3.158e-47	189.0	COG0611@1|root,COG0611@2|Bacteria,1V0SM@1239|Firmicutes,24J04@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158456_k127_107646_4	1191523.MROS_1190	1.804e-73	255.0	COG0101@1|root,COG0101@2|Bacteria	2|Bacteria	J	tRNA pseudouridine synthase activity	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158456_k127_107646_10	478741.JAFS01000002_gene624	5.684e-21	95.0	COG3536@1|root,COG3536@2|Bacteria,46VNP@74201|Verrucomicrobia,37H0M@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
SRR25158456_k127_107646_9	42256.RradSPS_0544	2.182e-22	113.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SRR25158456_k127_107646_3	756499.Desde_0779	4.138e-92	329.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,264F3@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158456_k127_107646_2	1121920.AUAU01000006_gene258	1.76e-98	336.0	COG2235@1|root,COG2235@2|Bacteria,3Y86Y@57723|Acidobacteria	57723|Acidobacteria	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158456_k127_107646_1	1267535.KB906767_gene3131	3.674e-152	511.0	COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria,2JI3C@204432|Acidobacteriia	204432|Acidobacteriia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_107646_8	1144888.CM001467_gene668	3.532e-25	109.0	2EH09@1|root,33ASB@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SRR25158456_k127_107646_13	563192.HMPREF0179_02111	0.0009869	50.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1RDNA@1224|Proteobacteria,42Q5I@68525|delta/epsilon subdivisions,2WIX0@28221|Deltaproteobacteria,2M8KB@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
SRR25158456_k127_107646_0	330214.NIDE3635	3.273e-201	640.0	COG4108@1|root,COG4108@2|Bacteria,3J0WP@40117|Nitrospirae	40117|Nitrospirae	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
SRR25158456_k127_107646_11	502025.Hoch_4942	4.217e-15	83.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,431QP@68525|delta/epsilon subdivisions,2WWXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1082420_2	1121920.AUAU01000004_gene798	1.065e-82	283.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,Hexapep
SRR25158456_k127_1082420_4	1379270.AUXF01000006_gene300	1.476e-41	171.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
SRR25158456_k127_1082420_3	195253.Syn6312_0602	1.281e-73	260.0	COG1044@1|root,COG1044@2|Bacteria,1G04G@1117|Cyanobacteria,1GYFH@1129|Synechococcus	1117|Cyanobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRR25158456_k127_1082420_7	1121396.KB893082_gene950	3.312e-11	70.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2MK60@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Outer membrane	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158456_k127_1082420_0	903818.KI912268_gene2245	1.21e-93	340.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158456_k127_1082420_6	926569.ANT_29070	1.117e-13	79.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158456_k127_1082420_1	326297.Sama_0488	2.183e-90	307.0	COG3291@1|root,COG3291@2|Bacteria,1NE5Q@1224|Proteobacteria,1TCNR@1236|Gammaproteobacteria,2Q8VQ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
SRR25158456_k127_1082420_5	404589.Anae109_3113	8.255e-17	80.0	COG1942@1|root,COG1942@2|Bacteria,1RHA5@1224|Proteobacteria,431G6@68525|delta/epsilon subdivisions,2WWH2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tautomerase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
SRR25158456_k127_1102174_1	1453501.JELR01000001_gene2884	1.501e-89	310.0	COG0657@1|root,COG3866@1|root,COG0657@2|Bacteria,COG3866@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,466TB@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Carboxylesterase family	aes	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
SRR25158456_k127_1102174_0	234267.Acid_7510	4.898e-177	599.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KA@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158456_k127_1102174_2	452637.Oter_4265	1.073e-55	215.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861
SRR25158456_k127_1104733_7	1449076.JOOE01000002_gene1278	3.526e-28	126.0	2EJ7I@1|root,33CYP@2|Bacteria,1PNKD@1224|Proteobacteria,2V169@28211|Alphaproteobacteria,2KB68@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1104733_5	1123269.NX02_27715	3.472e-48	178.0	COG1595@1|root,COG1595@2|Bacteria,1RIU9@1224|Proteobacteria,2UF2N@28211|Alphaproteobacteria,2KDZJ@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1104733_1	909663.KI867150_gene269	7.793e-231	739.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2MSEM@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158456_k127_1104733_3	880072.Desac_2706	4.02e-93	327.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria,2MQ4A@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Osmosensitive K channel His kinase sensor	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,PTS_EIIA_2,Usp
SRR25158456_k127_1104733_6	666684.AfiDRAFT_2303	7.048e-40	169.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2TSQ7@28211|Alphaproteobacteria,3JSZV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRR25158456_k127_1104733_0	1198114.AciX9_2438	3.301e-284	914.0	COG2216@1|root,COG2216@2|Bacteria,3Y302@57723|Acidobacteria,2JHQI@204432|Acidobacteriia	204432|Acidobacteriia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRR25158456_k127_1104733_2	1382359.JIAL01000001_gene493	2.163e-203	647.0	COG2060@1|root,COG2060@2|Bacteria,3Y2YP@57723|Acidobacteria,2JIFM@204432|Acidobacteriia	204432|Acidobacteriia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRR25158456_k127_1104733_4	1278073.MYSTI_00150	1.115e-75	273.0	2CB8G@1|root,2Z88H@2|Bacteria	2|Bacteria	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SRR25158456_k127_1121227_1	1122915.AUGY01000040_gene618	7.493e-66	249.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,4HBRW@91061|Bacilli,26REH@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function (DUF3492)	-	-	2.4.1.52	ko:K00712,ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT4	-	DUF3492,Glyco_trans_A_1,Glycos_transf_1
SRR25158456_k127_1121227_3	518766.Rmar_1777	2.005e-05	58.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes	976|Bacteroidetes	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_1121227_0	269799.Gmet_0011	3.254e-67	256.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,43C40@68525|delta/epsilon subdivisions,2X7EG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	fgrK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158456_k127_1121227_2	1123368.AUIS01000006_gene566	1.981e-49	202.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
SRR25158456_k127_1132514_1	1216007.AOPM01000073_gene1364	4.839e-55	217.0	COG1520@1|root,COG1520@2|Bacteria,1RB08@1224|Proteobacteria,1S2SZ@1236|Gammaproteobacteria,2Q47M@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158456_k127_1132514_3	1206729.BAFZ01000053_gene5279	3.837e-05	49.0	2B5K9@1|root,31YF9@2|Bacteria,2H0PR@201174|Actinobacteria,4G7YX@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1132514_2	1385517.N800_04515	1.238e-53	213.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Laminin_G_3,Reprolysin_4,VPEP
SRR25158456_k127_1132514_0	1121920.AUAU01000004_gene861	1.388e-58	215.0	COG1309@1|root,COG1309@2|Bacteria,3Y5K3@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158456_k127_1133546_0	1382359.JIAL01000001_gene416	3.367e-255	802.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria,2JI9D@204432|Acidobacteriia	204432|Acidobacteriia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158456_k127_1133546_2	502025.Hoch_3435	7.31e-29	122.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2YV3U@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158456_k127_1133546_1	518766.Rmar_0964	2.394e-43	176.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1FIZS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
SRR25158456_k127_1133546_3	909663.KI867149_gene3406	1.889e-09	65.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2MRYQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158456_k127_1134234_4	1116369.KB890024_gene4620	8.397e-11	64.0	COG0745@1|root,COG0745@2|Bacteria,1NCKY@1224|Proteobacteria,2TRPQ@28211|Alphaproteobacteria,43NNK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_1134234_3	1123261.AXDW01000007_gene2334	6.142e-39	156.0	COG3946@1|root,COG3946@2|Bacteria,1R7R5@1224|Proteobacteria,1S73H@1236|Gammaproteobacteria,1X4YR@135614|Xanthomonadales	135614|Xanthomonadales	U	Virulence protein	-	-	-	-	-	-	-	-	-	-	-	-	VirJ
SRR25158456_k127_1134234_0	1121918.ARWE01000001_gene3106	4.271e-214	700.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,42N7P@68525|delta/epsilon subdivisions,2WMCJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	-	DUF2156,LPG_synthase_TM
SRR25158456_k127_1134234_1	452637.Oter_1502	1.075e-94	316.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,3K7BH@414999|Opitutae	2|Bacteria	V	PFAM ABC transporter related	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_1134234_2	1297742.A176_02905	8.899e-43	179.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
SRR25158456_k127_1134364_1	204669.Acid345_2219	1.415e-96	347.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y9GC@57723|Acidobacteria,2JKTW@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158456_k127_1134364_0	290397.Adeh_4214	4.956e-263	829.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2YUCV@29|Myxococcales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
SRR25158456_k127_1134364_3	479434.Sthe_3163	3.055e-62	245.0	COG1252@1|root,COG1252@2|Bacteria,2G8F4@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158456_k127_1134364_2	1463909.KL585972_gene3468	1.19e-67	250.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158456_k127_1134364_5	880072.Desac_0727	9.818e-18	94.0	COG0802@1|root,COG0802@2|Bacteria,1PDPH@1224|Proteobacteria,42XZX@68525|delta/epsilon subdivisions,2WT4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158456_k127_1134364_4	926550.CLDAP_36650	7.722e-24	113.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
SRR25158456_k127_1143441_2	243231.GSU2313	2.088e-38	156.0	COG2199@1|root,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2WKG6@28221|Deltaproteobacteria,43W34@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response receiver-modulated diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158456_k127_1143441_0	258533.BN977_03702	1.512e-139	480.0	COG3590@1|root,COG3590@2|Bacteria,2ICCH@201174|Actinobacteria,23CSG@1762|Mycobacteriaceae	201174|Actinobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1143441_1	258533.BN977_03701	1.693e-71	263.0	COG2333@1|root,COG2333@2|Bacteria,2IP3R@201174|Actinobacteria,23D3U@1762|Mycobacteriaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_1143441_3	102129.Lepto7375DRAFT_7686	7.748e-14	86.0	COG1357@1|root,COG5635@1|root,COG1357@2|Bacteria,COG5635@2|Bacteria,1G3AI@1117|Cyanobacteria,1H7B7@1150|Oscillatoriales	1117|Cyanobacteria	T	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide
SRR25158456_k127_1147975_1	269799.Gmet_1175	3.571e-06	52.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Robl_LC7
SRR25158456_k127_1147975_2	643473.KB235930_gene4040	0.0001653	53.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G2FI@1117|Cyanobacteria,1HKPG@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_1147975_0	204669.Acid345_3335	1.215e-116	396.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,3Y7I5@57723|Acidobacteria,2JMTE@204432|Acidobacteriia	204432|Acidobacteriia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158456_k127_1151383_11	234267.Acid_4826	1.575e-36	141.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1151383_17	134676.ACPL_3486	1.397e-22	107.0	COG2085@1|root,COG2085@2|Bacteria,2GMN3@201174|Actinobacteria,4DDWA@85008|Micromonosporales	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158456_k127_1151383_21	314278.NB231_02303	1.788e-10	62.0	COG1724@1|root,COG1724@2|Bacteria,1NP7S@1224|Proteobacteria,1SUVY@1236|Gammaproteobacteria,1X1KJ@135613|Chromatiales	135613|Chromatiales	N	periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1151383_23	1499967.BAYZ01000096_gene4319	9.09e-08	54.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158456_k127_1151383_19	631362.Thi970DRAFT_00649	1.002e-17	84.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158456_k127_1151383_18	1284352.AOIG01000011_gene1307	2.107e-22	107.0	COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,26TYK@186822|Paenibacillaceae	91061|Bacilli	E	lipolytic protein G-D-S-L family	ypmR1	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158456_k127_1151383_5	861299.J421_1094	4.439e-96	319.0	COG0702@1|root,COG0702@2|Bacteria,1ZUY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1151383_2	1198114.AciX9_1564	2.153e-109	378.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria,2JHY4@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_1151383_9	1123368.AUIS01000008_gene2230	1.912e-74	267.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1MVI4@1224|Proteobacteria,1S1IH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158456_k127_1151383_4	243231.GSU2064	7.9e-100	347.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158456_k127_1151383_16	903818.KI912268_gene747	2.453e-23	110.0	COG0009@1|root,COG0009@2|Bacteria,3Y43Z@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
SRR25158456_k127_1151383_12	215803.DB30_7610	3.794e-31	142.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158456_k127_1151383_6	926550.CLDAP_13710	5.285e-96	330.0	COG2239@1|root,COG2239@2|Bacteria,2G6H7@200795|Chloroflexi	200795|Chloroflexi	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158456_k127_1151383_8	330214.NIDE3081	1.404e-78	269.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158456_k127_1151383_3	234267.Acid_1595	4.694e-100	340.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158456_k127_1151383_13	234267.Acid_1594	3.823e-31	126.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158456_k127_1151383_14	522306.CAP2UW1_1196	2.313e-28	129.0	COG0457@1|root,COG1715@1|root,COG0457@2|Bacteria,COG1715@2|Bacteria,1MWRF@1224|Proteobacteria,2VVW1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7
SRR25158456_k127_1151383_20	1170562.Cal6303_4743	2.839e-11	77.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HMGW@1161|Nostocales	1117|Cyanobacteria	K	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_12,TPR_7,TPR_8
SRR25158456_k127_1151383_15	861299.J421_1529	7.543e-25	115.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158456_k127_1151383_22	204669.Acid345_4245	3.977e-10	74.0	COG0457@1|root,COG0457@2|Bacteria,3Y85C@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1151383_1	886293.Sinac_6510	4.962e-138	472.0	COG1643@1|root,COG1643@2|Bacteria,2IX3C@203682|Planctomycetes	203682|Planctomycetes	L	ATP-dependent helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
SRR25158456_k127_1151383_0	1144275.COCOR_04452	2.483e-255	822.0	COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1151383_7	1173023.KE650771_gene1726	5.135e-94	337.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,1GHDU@1117|Cyanobacteria,1JKFU@1189|Stigonemataceae	1117|Cyanobacteria	Q	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,HemolysinCabind,LTD
SRR25158456_k127_1151383_10	234267.Acid_3219	1.991e-39	170.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1155438_1	240292.Ava_4731	2.705e-52	211.0	2BKA1@1|root,32EQ8@2|Bacteria,1GJ4Q@1117|Cyanobacteria,1HQEC@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1155438_0	103690.17131134	1.13e-204	688.0	COG1511@1|root,COG1511@2|Bacteria,1G29D@1117|Cyanobacteria,1HQZW@1161|Nostocales	1117|Cyanobacteria	S	Tubulin like	-	-	-	-	-	-	-	-	-	-	-	-	Tubulin_2
SRR25158456_k127_1155438_2	240292.Ava_4733	9.663e-30	134.0	COG2304@1|root,COG2304@2|Bacteria,1GE29@1117|Cyanobacteria,1HQQ8@1161|Nostocales	1117|Cyanobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158456_k127_1155438_3	903818.KI912268_gene1501	3.055e-06	60.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria,3Y77C@57723|Acidobacteria	57723|Acidobacteria	G	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,Peptidase_C14,Polysacc_deac_1,TPR_2,WD40
SRR25158456_k127_1159425_4	1079986.JH164837_gene5692	6.893e-06	58.0	COG1396@1|root,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,TPR_12,TPR_16,TPR_8
SRR25158456_k127_1159425_3	762968.HMPREF9441_02118	2.84e-07	62.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
SRR25158456_k127_1159425_1	756272.Plabr_1090	1.498e-31	141.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4375,HEAT_2
SRR25158456_k127_1159425_0	561229.Dd1591_0446	5.646e-82	283.0	2B14P@1|root,31TII@2|Bacteria,1QR95@1224|Proteobacteria,1SN3G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_1165412_19	1173025.GEI7407_3467	7.386e-10	68.0	2CNI4@1|root,32SH5@2|Bacteria,1G80S@1117|Cyanobacteria,1HD8Z@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1165412_14	240292.Ava_3249	1.236e-31	133.0	COG2442@1|root,COG2442@2|Bacteria,1G4E6@1117|Cyanobacteria,1HN4K@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_1165412_1	1121920.AUAU01000018_gene1783	0.0	1101.0	COG1506@1|root,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158456_k127_1165412_3	283699.D172_1923	1.251e-189	621.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria,2PZTK@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	ERAP1-like C-terminal domain	-	-	3.4.11.14,3.4.11.2	ko:K01256,ko:K01263	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158456_k127_1165412_12	153948.NAL212_0916	4.301e-44	175.0	COG0628@1|root,COG0628@2|Bacteria,1PTH3@1224|Proteobacteria	1224|Proteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158456_k127_1165412_15	646529.Desaci_2738	4.482e-26	113.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,265AW@186807|Peptococcaceae	186801|Clostridia	K	PFAM Penicillinase repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
SRR25158456_k127_1165412_13	1536775.H70737_15575	3.217e-38	162.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,4HB9X@91061|Bacilli,26XA3@186822|Paenibacillaceae	91061|Bacilli	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4309,Peptidase_M56
SRR25158456_k127_1165412_9	267608.RSc2614	9.409e-76	260.0	COG4271@1|root,COG4271@2|Bacteria,1RHKG@1224|Proteobacteria,2VVAD@28216|Betaproteobacteria,1KAX0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like
SRR25158456_k127_1165412_18	1173027.Mic7113_4930	1.505e-10	65.0	2E46G@1|root,32Z2E@2|Bacteria,1G8V4@1117|Cyanobacteria,1HGBS@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1165412_16	1173027.Mic7113_4931	1.596e-23	102.0	COG2929@1|root,COG2929@2|Bacteria,1G7VS@1117|Cyanobacteria,1HHKU@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR25158456_k127_1165412_2	234267.Acid_6465	1.602e-290	922.0	COG1629@1|root,COG4771@2|Bacteria,3Y33S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
SRR25158456_k127_1165412_6	1267534.KB906758_gene2269	1.471e-93	316.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	pyrD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.3.1.14,1.3.5.2,1.3.98.1	ko:K00226,ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158456_k127_1165412_7	1123508.JH636451_gene5944	3.868e-86	293.0	COG3239@1|root,COG3239@2|Bacteria,2J09R@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158456_k127_1165412_5	1242864.D187_010034	1.229e-107	369.0	COG0531@1|root,COG0531@2|Bacteria,1NRYF@1224|Proteobacteria,43DN8@68525|delta/epsilon subdivisions,2X6GY@28221|Deltaproteobacteria,2Z3B2@29|Myxococcales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158456_k127_1165412_0	502025.Hoch_5404	0.0	1140.0	COG1452@1|root,COG1452@2|Bacteria,1QW3G@1224|Proteobacteria,43CZ5@68525|delta/epsilon subdivisions,2X87D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1165412_17	402626.Rpic_3874	1.064e-10	72.0	2EHEW@1|root,33B6U@2|Bacteria,1NNBP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1165412_20	1132855.KB913035_gene727	3.337e-09	66.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria,2KN12@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158456_k127_1165412_8	42256.RradSPS_0832	2.573e-80	283.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4CU00@84995|Rubrobacteria	84995|Rubrobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158456_k127_1165412_10	324925.Ppha_0327	3.966e-71	245.0	COG0551@1|root,COG0551@2|Bacteria,1FF54@1090|Chlorobi	1090|Chlorobi	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1165412_11	338969.Rfer_0864	5.974e-62	218.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VRBT@28216|Betaproteobacteria,4AE1V@80864|Comamonadaceae	28216|Betaproteobacteria	C	2Fe-2S -binding domain protein	iorA	-	1.17.2.1	ko:K18029	ko00760,ko01120,map00760,map01120	M00622	R09473	RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158456_k127_1165412_4	338969.Rfer_0863	8.752e-148	488.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHII@28216|Betaproteobacteria,4AJXE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158456_k127_1167965_1	935863.AWZR01000002_gene1046	2.48e-128	421.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1X5QJ@135614|Xanthomonadales	135614|Xanthomonadales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158456_k127_1167965_2	1125863.JAFN01000001_gene3208	4.163e-123	402.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42SXS@68525|delta/epsilon subdivisions,2X5BQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
SRR25158456_k127_1167965_4	1444711.CCJF01000005_gene1005	7.979e-16	89.0	COG1994@1|root,COG1994@2|Bacteria,2JFYC@204428|Chlamydiae	204428|Chlamydiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
SRR25158456_k127_1167965_0	1430440.MGMSRv2_1858	1.454e-153	526.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JQ4H@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS_9
SRR25158456_k127_1167965_3	981369.JQMJ01000004_gene1018	2.397e-24	119.0	COG3291@1|root,COG3291@2|Bacteria,2HHTF@201174|Actinobacteria,2NHQJ@228398|Streptacidiphilus	201174|Actinobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Phosphoesterase,fn3
SRR25158456_k127_1171387_1	1121007.AUML01000030_gene133	9.879e-181	589.0	COG0454@1|root,COG3321@1|root,COG0456@2|Bacteria,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia,2YHN1@290174|Aquimarina	976|Bacteroidetes	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_1171387_2	1242864.D187_006563	3.26e-88	297.0	COG3823@1|root,COG3823@2|Bacteria,1R9YU@1224|Proteobacteria,42RYU@68525|delta/epsilon subdivisions,2WNVI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
SRR25158456_k127_1171387_0	483219.LILAB_06205	0.0	1183.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX1A@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
SRR25158456_k127_1171387_3	1278073.MYSTI_00515	1.839e-75	267.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42RBE@68525|delta/epsilon subdivisions,2WN7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_1175020_0	1304885.AUEY01000030_gene2414	9.636e-226	721.0	COG2203@1|root,COG2804@1|root,COG2203@2|Bacteria,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria,2MJCC@213118|Desulfobacterales	28221|Deltaproteobacteria	NTU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,T2SSE,T2SSE_N
SRR25158456_k127_1175020_1	1463825.JNXC01000003_gene4043	6.079e-186	597.0	2EWB2@1|root,33PPT@2|Bacteria,2H3ZK@201174|Actinobacteria,4E84Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1175020_2	502025.Hoch_1343	2.331e-16	93.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YU5N@29|Myxococcales	28221|Deltaproteobacteria	T	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
SRR25158456_k127_1178005_7	1144275.COCOR_03309	1.449e-47	186.0	COG1305@1|root,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
SRR25158456_k127_1178005_8	398767.Glov_3186	3.374e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	cold-shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158456_k127_1178005_5	1434325.AZQN01000003_gene2247	7.707e-71	267.0	COG1409@1|root,COG2374@1|root,COG5492@1|root,COG1409@2|Bacteria,COG2374@2|Bacteria,COG5492@2|Bacteria,4NHMV@976|Bacteroidetes,47UBQ@768503|Cytophagia	976|Bacteroidetes	N	Polysaccharide lyase family 8, N terminal alpha-helical domain	cslA	-	4.2.2.5	ko:K19049	-	-	-	-	ko00000,ko01000	-	PL8	-	DUF1573,Lyase_8,Lyase_8_C,Lyase_8_N
SRR25158456_k127_1178005_10	313628.LNTAR_07709	9.172e-12	68.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07445	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158456_k127_1178005_9	794903.OPIT5_19020	1.603e-14	84.0	COG1169@1|root,COG1943@1|root,COG1169@2|Bacteria,COG1943@2|Bacteria,46TTI@74201|Verrucomicrobia,3K7NU@414999|Opitutae	414999|Opitutae	HQ	Isochorismate synthase	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158456_k127_1178005_6	227377.CBU_1788	5.153e-49	181.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
SRR25158456_k127_1178005_1	1519464.HY22_00720	1.811e-158	510.0	COG0577@1|root,COG0577@2|Bacteria,1FDBN@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_1178005_2	1519464.HY22_00710	5.376e-156	525.0	COG0577@1|root,COG0577@2|Bacteria,1FDSK@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_1178005_3	452637.Oter_1637	1.843e-120	432.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia,3K76J@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158456_k127_1178005_0	192952.MM_1479	6.008e-272	885.0	COG0553@1|root,arCOG00883@2157|Archaea	2157|Archaea	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
SRR25158456_k127_1178005_4	1123508.JH636439_gene661	4.904e-75	260.0	COG4279@1|root,COG4279@2|Bacteria,2IYXU@203682|Planctomycetes	203682|Planctomycetes	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
SRR25158456_k127_1181784_15	1297742.A176_02426	1.638e-38	149.0	COG3795@1|root,COG3795@2|Bacteria,1RKYW@1224|Proteobacteria,43DU4@68525|delta/epsilon subdivisions,2WYVK@28221|Deltaproteobacteria,2Z0QY@29|Myxococcales	28221|Deltaproteobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158456_k127_1181784_9	448385.sce1490	3.439e-51	188.0	COG3795@1|root,COG3795@2|Bacteria,1Q42B@1224|Proteobacteria,439VS@68525|delta/epsilon subdivisions,2X59V@28221|Deltaproteobacteria,2Z0B4@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158456_k127_1181784_6	880073.Calab_2482	1.006e-104	355.0	COG0534@1|root,COG0534@2|Bacteria,2NPFE@2323|unclassified Bacteria	2|Bacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
SRR25158456_k127_1181784_18	290397.Adeh_1321	8.485e-18	92.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158456_k127_1181784_12	1396141.BATP01000061_gene4541	8.217e-46	184.0	28N64@1|root,2ZBFG@2|Bacteria,46Z9S@74201|Verrucomicrobia,2IWQS@203494|Verrucomicrobiae	2|Bacteria	S	Peptidase of plants and bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BSP
SRR25158456_k127_1181784_3	861299.J421_5600	3.964e-119	413.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
SRR25158456_k127_1181784_1	861299.J421_5610	6.383e-161	520.0	COG1129@1|root,COG1129@2|Bacteria,1ZVAU@142182|Gemmatimonadetes	2|Bacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158456_k127_1181784_4	861299.J421_5609	1.467e-114	389.0	COG1879@1|root,COG1879@2|Bacteria,1ZV3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
SRR25158456_k127_1181784_0	204669.Acid345_3122	0.0	1047.0	COG0383@1|root,COG0383@2|Bacteria,3Y2RJ@57723|Acidobacteria,2JI5W@204432|Acidobacteriia	204432|Acidobacteriia	G	glycoside hydrolase family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158456_k127_1181784_16	272134.KB731324_gene4210	1.59e-31	141.0	COG0457@1|root,COG2852@1|root,COG0457@2|Bacteria,COG2852@2|Bacteria,1G1QI@1117|Cyanobacteria,1H6XA@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
SRR25158456_k127_1181784_17	84531.JMTZ01000137_gene1432	2.965e-30	136.0	COG0860@1|root,COG3979@1|root,COG0860@2|Bacteria,COG3979@2|Bacteria,1QVSC@1224|Proteobacteria	1224|Proteobacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1181784_19	1298860.AUEM01000003_gene3360	1.232e-16	93.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
SRR25158456_k127_1181784_8	521719.ATXQ01000002_gene2511	1.909e-52	194.0	COG1423@1|root,COG1423@2|Bacteria,1R3S2@1224|Proteobacteria,1S7YK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ATP-dependent DNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
SRR25158456_k127_1181784_11	631362.Thi970DRAFT_00450	5.1e-49	180.0	2BNF2@1|root,32H2U@2|Bacteria,1RKYP@1224|Proteobacteria,1SAIS@1236|Gammaproteobacteria,1X1H1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1181784_2	395493.BegalDRAFT_2399	1.008e-144	471.0	COG4637@1|root,COG4938@1|root,COG4637@2|Bacteria,COG4938@2|Bacteria,1NEEG@1224|Proteobacteria,1RZMD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
SRR25158456_k127_1181784_7	91464.S7335_5066	7.368e-58	222.0	COG2197@1|root,COG2197@2|Bacteria,1G5A4@1117|Cyanobacteria,1H1TX@1129|Synechococcus	1117|Cyanobacteria	K	TK COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158456_k127_1181784_13	99598.Cal7507_3661	1.137e-43	176.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1GCBY@1117|Cyanobacteria,1HRSA@1161|Nostocales	1117|Cyanobacteria	T	PFAM Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
SRR25158456_k127_1181784_5	1294143.H681_10170	1.131e-108	365.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mexE	-	-	ko:K18298	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_1181784_10	1121943.KB899999_gene1441	2.789e-50	182.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XH4Q@135619|Oceanospirillales	135619|Oceanospirillales	V	efflux pump	-	-	-	ko:K18299	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.16	-	-	ACR_tran
SRR25158456_k127_11880_2	1122611.KB903939_gene312	1.146e-42	169.0	28QBS@1|root,2ZCUB@2|Bacteria,2HBTV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_11880_0	1122611.KB903939_gene313	5.479e-134	458.0	COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,2H5BJ@201174|Actinobacteria	201174|Actinobacteria	KLT	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158456_k127_11880_7	1463821.JOGR01000001_gene1495	1.218e-22	111.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2GJYH@201174|Actinobacteria,4EXTU@85014|Glycomycetales	201174|Actinobacteria	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
SRR25158456_k127_11880_4	1379698.RBG1_1C00001G0743	2.997e-33	139.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
SRR25158456_k127_11880_3	1120965.AUBV01000012_gene1480	1.713e-37	149.0	COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,47QV5@768503|Cytophagia	976|Bacteroidetes	S	Acyl carrier protein phosphodiesterase	acpH	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
SRR25158456_k127_11880_1	448385.sce5671	3.841e-60	217.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158456_k127_11880_6	313606.M23134_04112	1.28e-23	105.0	COG0454@1|root,COG0454@2|Bacteria,4NX2R@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158456_k127_11880_5	378806.STAUR_0238	6.217e-25	119.0	COG2312@1|root,COG2312@2|Bacteria,1NEZB@1224|Proteobacteria,433VP@68525|delta/epsilon subdivisions,2X3PC@28221|Deltaproteobacteria,2YWR8@29|Myxococcales	28221|Deltaproteobacteria	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg,Erythro_esteras
SRR25158456_k127_11880_8	522772.Dacet_1672	3.69e-14	72.0	COG0618@1|root,COG0618@2|Bacteria,2GGCR@200930|Deferribacteres	200930|Deferribacteres	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1189259_2	55207.KP22_03140	1.047e-55	202.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1MQ3B@122277|Pectobacterium	1236|Gammaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158456_k127_1189259_0	290397.Adeh_0789	8.623e-290	908.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158456_k127_1189259_3	502025.Hoch_5003	6.673e-31	124.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2YVP9@29|Myxococcales	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158456_k127_1189259_1	583345.Mmol_0769	3.002e-74	262.0	28IX1@1|root,2ZC5T@2|Bacteria,1R35E@1224|Proteobacteria,2VQUH@28216|Betaproteobacteria,2KKKU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
SRR25158456_k127_1189259_4	1229203.KI301992_gene2312	2.708e-12	80.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158456_k127_1191846_3	1117379.BABA_13742	1.035e-10	67.0	COG1028@1|root,COG1028@2|Bacteria,1TPDB@1239|Firmicutes,4HAKR@91061|Bacilli,1ZDEP@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	ykuF	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158456_k127_1191846_4	1340493.JNIF01000003_gene4232	7.684e-05	52.0	COG5569@1|root,COG5569@2|Bacteria	2|Bacteria	P	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusF	-	-	ko:K07152,ko:K07810	ko02020,map02020	-	-	-	ko00000,ko00001,ko03029	2.A.6.1.4	-	-	Copper-bind,CusF_Ec
SRR25158456_k127_1191846_2	525904.Tter_1452	1.147e-87	304.0	COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria	2|Bacteria	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158456_k127_1191846_0	1382356.JQMP01000003_gene2445	1.41e-121	404.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,27XNM@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158456_k127_1191846_1	682795.AciX8_3691	1.779e-97	336.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria,2JHV2@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158456_k127_1204324_4	204669.Acid345_2714	5.255e-21	108.0	COG2010@1|root,COG2010@2|Bacteria,3Y5MU@57723|Acidobacteria,2JJWK@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158456_k127_1204324_1	204669.Acid345_2712	2.281e-165	533.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
SRR25158456_k127_1204324_0	204669.Acid345_2713	5.362e-187	602.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
SRR25158456_k127_1204324_2	234267.Acid_4435	3.646e-136	460.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1204324_3	234267.Acid_7896	1.115e-55	207.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SRR25158456_k127_1204324_5	234267.Acid_6725	2.287e-08	67.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1209727_1	1395571.TMS3_0107765	2.759e-48	178.0	29T71@1|root,30EDT@2|Bacteria,1RFDY@1224|Proteobacteria,1S482@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1209727_3	329726.AM1_0674	1.593e-40	158.0	COG1848@1|root,COG1848@2|Bacteria,1G51H@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1209727_6	29306.JOBE01000036_gene5299	2.512e-07	58.0	COG2169@1|root,COG2169@2|Bacteria,2IJD4@201174|Actinobacteria	201174|Actinobacteria	F	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
SRR25158456_k127_1209727_9	1392498.JQLH01000001_gene363	0.000714	52.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia,2PG4G@252356|Maribacter	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158456_k127_1209727_8	1246995.AFR_39295	0.0004154	50.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4DC3B@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158456_k127_1209727_5	234267.Acid_7645	2.905e-32	130.0	COG0517@1|root,COG0517@2|Bacteria,3Y7MI@57723|Acidobacteria	57723|Acidobacteria	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
SRR25158456_k127_1209727_4	1163407.UU7_09380	1.8e-36	143.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,1S90R@1236|Gammaproteobacteria,1X7IR@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
SRR25158456_k127_1209727_2	1123278.KB893424_gene1786	4.999e-46	180.0	COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes,47N5H@768503|Cytophagia	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158456_k127_1209727_7	658086.HMPREF0994_04544	6.351e-06	53.0	COG2207@1|root,COG2207@2|Bacteria,1TRXE@1239|Firmicutes,24CWF@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
SRR25158456_k127_1209727_0	56107.Cylst_5527	6.867e-90	305.0	COG4870@1|root,COG4870@2|Bacteria,1G85R@1117|Cyanobacteria,1HNEI@1161|Nostocales	1117|Cyanobacteria	O	PFAM Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
SRR25158456_k127_1212462_1	1268237.G114_17961	5.603e-79	279.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1Y3Q8@135624|Aeromonadales	135624|Aeromonadales	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	deaD	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158456_k127_1212462_0	926550.CLDAP_19060	4.07e-90	322.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158456_k127_1217637_3	1267534.KB906754_gene2794	1.316e-59	228.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158456_k127_1217637_7	1191523.MROS_1301	4.152e-48	179.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158456_k127_1217637_1	497964.CfE428DRAFT_0927	9.122e-99	343.0	COG0644@1|root,COG0644@2|Bacteria,46TJ0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158456_k127_1217637_2	671143.DAMO_3038	4.747e-72	250.0	COG0586@1|root,COG0586@2|Bacteria,2NQ0I@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR25158456_k127_1217637_0	502025.Hoch_4718	5.484e-104	344.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
SRR25158456_k127_1217637_10	1267533.KB906733_gene2848	1.503e-11	70.0	2E32R@1|root,32Y2Y@2|Bacteria,3Y5RV@57723|Acidobacteria,2JNI4@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1217637_4	1379270.AUXF01000007_gene855	3.166e-55	209.0	2C4IX@1|root,32RE1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158456_k127_1217637_8	1380347.JNII01000007_gene533	2.763e-27	118.0	2ECJT@1|root,336HX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1217637_5	1041159.AZUW01000006_gene1755	1.505e-51	199.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2U9AG@28211|Alphaproteobacteria,4BF17@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158456_k127_1217637_12	32057.KB217478_gene6919	4.444e-10	65.0	COG2856@1|root,COG3093@1|root,COG2856@2|Bacteria,COG3093@2|Bacteria,1G4I8@1117|Cyanobacteria,1HU7Z@1161|Nostocales	1117|Cyanobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
SRR25158456_k127_1217637_6	861299.J421_0970	3.933e-51	192.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	fes	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
SRR25158456_k127_1217637_11	469383.Cwoe_3783	2.09e-11	65.0	COG2411@1|root,COG2411@2|Bacteria,2HRSA@201174|Actinobacteria,4CTVC@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1222497_2	1121898.Q766_01880	2.588e-16	81.0	COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes,1I4DQ@117743|Flavobacteriia,2NZZG@237|Flavobacterium	976|Bacteroidetes	L	T5orf172 domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
SRR25158456_k127_1222497_0	502025.Hoch_5321	1.632e-99	341.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,43A4R@68525|delta/epsilon subdivisions,2X23J@28221|Deltaproteobacteria,2YUTA@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SRR25158456_k127_1222497_1	1300345.LF41_48	9.416e-44	179.0	COG0028@1|root,COG1520@1|root,COG3391@1|root,COG3693@1|root,COG0028@2|Bacteria,COG1520@2|Bacteria,COG3391@2|Bacteria,COG3693@2|Bacteria,1QYUP@1224|Proteobacteria	1224|Proteobacteria	EH	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
SRR25158456_k127_12318_1	1089550.ATTH01000001_gene1134	5.121e-09	62.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1FIPJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158456_k127_12318_2	1114964.L485_04060	1.021e-05	58.0	COG0457@1|root,COG0457@2|Bacteria,1PDUB@1224|Proteobacteria,2TTYN@28211|Alphaproteobacteria,2K0P8@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_21
SRR25158456_k127_12318_3	234267.Acid_3490	0.0006934	52.0	2DBAV@1|root,2Z84I@2|Bacteria,3Y9AH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_12318_0	1121920.AUAU01000028_gene1372	1.166e-75	287.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_1231812_2	886293.Sinac_7353	8.964e-68	244.0	COG3361@1|root,COG3361@2|Bacteria,2IZQT@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
SRR25158456_k127_1231812_3	457570.Nther_1438	5.285e-37	149.0	COG1215@1|root,COG1215@2|Bacteria,1UHZ3@1239|Firmicutes,24G8E@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_1231812_5	1144275.COCOR_07410	6.051e-09	66.0	COG5608@1|root,COG5608@2|Bacteria,1NIJH@1224|Proteobacteria,42XTV@68525|delta/epsilon subdivisions,2WSSA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
SRR25158456_k127_1231812_1	706587.Desti_4883	1.999e-71	256.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,42YIF@68525|delta/epsilon subdivisions,2WU4S@28221|Deltaproteobacteria,2MQET@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
SRR25158456_k127_1231812_6	1122228.AQXR01000008_gene725	0.0001129	53.0	COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4CZUH@85004|Bifidobacteriales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158456_k127_1231812_4	523791.Kkor_0233	3.043e-35	145.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1XJ89@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158456_k127_1231812_0	1283299.AUKG01000003_gene204	1.106e-125	419.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158456_k127_123734_4	234267.Acid_6282	2.478e-36	142.0	COG0745@1|root,COG0745@2|Bacteria,3Y38C@57723|Acidobacteria	57723|Acidobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_123734_2	330214.NIDE2416	8.871e-68	237.0	COG0704@1|root,COG0704@2|Bacteria,3J0M6@40117|Nitrospirae	40117|Nitrospirae	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158456_k127_123734_0	1121456.ATVA01000018_gene368	9.724e-113	384.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2M7VZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158456_k127_123734_1	1278073.MYSTI_05251	3.823e-102	349.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
SRR25158456_k127_123734_3	378806.STAUR_5630	1.75e-58	207.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158456_k127_1247111_4	1380394.JADL01000003_gene5179	9.642e-84	289.0	COG0703@1|root,COG1396@1|root,COG0703@2|Bacteria,COG1396@2|Bacteria,1MX66@1224|Proteobacteria,2TQWU@28211|Alphaproteobacteria,2JSJ6@204441|Rhodospirillales	204441|Rhodospirillales	EK	Shikimate kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,SKI
SRR25158456_k127_1247111_16	404589.Anae109_2046	0.0005181	51.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158456_k127_1247111_12	509191.AEDB02000048_gene4671	6.176e-06	59.0	COG4932@1|root,COG4932@2|Bacteria,1UTNT@1239|Firmicutes,253Q5@186801|Clostridia,3WQD4@541000|Ruminococcaceae	186801|Clostridia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1247111_10	234267.Acid_5626	4.04e-09	70.0	COG5549@1|root,COG5549@2|Bacteria	234267.Acid_5626|-	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1247111_9	671143.DAMO_2968	9.042e-33	148.0	COG0251@1|root,COG0251@2|Bacteria,2NPSA@2323|unclassified Bacteria	2|Bacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Pentapeptide,Ribonuc_L-PSP
SRR25158456_k127_1247111_13	8932.XP_005508415.1	0.0003037	48.0	2CW9H@1|root,2RTXW@2759|Eukaryota,38VYN@33154|Opisthokonta,3CCXZ@33208|Metazoa,3DM6X@33213|Bilateria,48K21@7711|Chordata,49IU4@7742|Vertebrata,4GWIB@8782|Aves	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1247111_14	349124.Hhal_0678	0.0003119	53.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1WYQZ@135613|Chromatiales	135613|Chromatiales	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158456_k127_1247111_8	266117.Rxyl_2726	6.278e-38	166.0	COG3301@1|root,COG3301@2|Bacteria,2GJ4S@201174|Actinobacteria,4CQ3J@84995|Rubrobacteria	84995|Rubrobacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158456_k127_1247111_1	204669.Acid345_1050	4.775e-218	706.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria,2JHXV@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158456_k127_1247111_2	639030.JHVA01000001_gene3124	1.24e-210	685.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria,2JHXV@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158456_k127_1247111_15	1144275.COCOR_01937	0.000357	50.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158456_k127_1247111_6	1356852.N008_21530	5.013e-67	246.0	COG3673@1|root,COG3673@2|Bacteria,4NHDR@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
SRR25158456_k127_1247111_3	204669.Acid345_2292	8.226e-110	377.0	COG0437@1|root,COG0437@2|Bacteria,3Y47T@57723|Acidobacteria,2JMIW@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11
SRR25158456_k127_1247111_0	204669.Acid345_2291	0.0	1054.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,3Y47M@57723|Acidobacteria,2JKQK@204432|Acidobacteriia	204432|Acidobacteriia	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158456_k127_1247111_7	204669.Acid345_2290	4.375e-65	228.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03470	Fer2_4,Fer4,Fer4_21,Fer4_7
SRR25158456_k127_1247111_5	316274.Haur_2934	6.157e-77	265.0	COG3548@1|root,COG3548@2|Bacteria,2G9XI@200795|Chloroflexi,377QW@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158456_k127_1247111_11	861299.J421_6139	5.756e-06	52.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_125146_1	204669.Acid345_1052	9.384e-123	422.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158456_k127_125146_4	1487953.JMKF01000064_gene4735	6.509e-47	172.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1HAQ3@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158456_k127_125146_7	330214.NIDE3035	1.522e-30	137.0	COG2121@1|root,COG2121@2|Bacteria,3J1AI@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SRR25158456_k127_125146_6	1444309.JAQG01000005_gene4303	5.53e-45	175.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,26T1M@186822|Paenibacillaceae	91061|Bacilli	S	Stress-induced protein	yloC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158456_k127_125146_5	768066.HELO_4403	7.136e-46	174.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1XJ5P@135619|Oceanospirillales	135619|Oceanospirillales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158456_k127_125146_2	713586.KB900536_gene2331	6.001e-110	369.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158456_k127_125146_3	404589.Anae109_1500	8.056e-71	246.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158456_k127_125146_0	234267.Acid_0690	7.499e-170	559.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158456_k127_125501_2	1442599.JAAN01000035_gene641	1.649e-135	452.0	COG1228@1|root,COG1228@2|Bacteria,1RCA0@1224|Proteobacteria,1S08B@1236|Gammaproteobacteria,1X5NR@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CIA30
SRR25158456_k127_125501_3	1144275.COCOR_02615	7.03e-100	335.0	COG0730@1|root,COG0730@2|Bacteria,1NJ47@1224|Proteobacteria,42QRS@68525|delta/epsilon subdivisions,2WN5M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158456_k127_125501_5	1144275.COCOR_02614	3.365e-20	100.0	COG4272@1|root,COG4272@2|Bacteria	2|Bacteria	S	membrane	ywjH	-	-	-	-	-	-	-	-	-	-	-	DUF1634
SRR25158456_k127_125501_6	1499967.BAYZ01000011_gene5223	7.587e-17	88.0	28T3T@1|root,2ZFCV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_125501_0	29581.BW37_00870	0.0	1347.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,2WBDI@28216|Betaproteobacteria,475K6@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158456_k127_125501_4	1122609.AUGT01000009_gene3145	2.349e-59	239.0	COG1361@1|root,COG2304@1|root,COG2373@1|root,COG3292@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,COG2373@2|Bacteria,COG3292@2|Bacteria,2I8F1@201174|Actinobacteria	201174|Actinobacteria	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SRR25158456_k127_125501_1	324602.Caur_0412	1.513e-180	638.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2GABV@200795|Chloroflexi,3752H@32061|Chloroflexia	32061|Chloroflexia	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
SRR25158456_k127_1256302_0	326427.Cagg_3460	3.245e-171	544.0	COG1899@1|root,COG1899@2|Bacteria,2G7R7@200795|Chloroflexi,374VZ@32061|Chloroflexia	32061|Chloroflexia	O	PFAM deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158456_k127_1256302_1	886293.Sinac_6279	3.02e-36	145.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158456_k127_1256302_2	861299.J421_1461	4.693e-34	152.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
SRR25158456_k127_1256302_5	1173264.KI913949_gene3688	8.223e-07	63.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158456_k127_1256302_4	118173.KB235914_gene3941	2.066e-07	64.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158456_k127_1256302_3	1267533.KB906735_gene4949	7.356e-24	118.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1259873_6	82654.Pse7367_0992	1.684e-23	106.0	COG4106@1|root,COG4106@2|Bacteria,1GQ61@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158456_k127_1259873_3	1123060.JONP01000016_gene5455	5.085e-47	192.0	COG0546@1|root,COG0546@2|Bacteria,1RCPM@1224|Proteobacteria,2VF7A@28211|Alphaproteobacteria,2JVE8@204441|Rhodospirillales	28211|Alphaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158456_k127_1259873_1	1089550.ATTH01000001_gene1968	4.97e-86	297.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1FJUG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158456_k127_1259873_4	713586.KB900536_gene2659	9.081e-40	152.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
SRR25158456_k127_1259873_0	1254432.SCE1572_18340	5.999e-175	558.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158456_k127_1259873_2	1267535.KB906767_gene1283	6.298e-83	291.0	COG1187@1|root,COG1187@2|Bacteria,3Y6Y9@57723|Acidobacteria,2JP1I@204432|Acidobacteriia	204432|Acidobacteriia	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158456_k127_1264591_11	33035.JPJF01000028_gene2815	5.885e-06	57.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3Y086@572511|Blautia	186801|Clostridia	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
SRR25158456_k127_1264591_4	148960.XP_006957818.1	5.892e-31	128.0	COG0127@1|root,KOG3222@2759|Eukaryota,38DZ3@33154|Opisthokonta,3P1W0@4751|Fungi,3V0HN@5204|Basidiomycota	4751|Fungi	F	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions	HAM1	GO:0003674,GO:0003824,GO:0004170,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008828,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036217,GO:0036218,GO:0036219,GO:0036220,GO:0036221,GO:0036222,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0047840,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	2.7.4.3	ko:K01519,ko:K18532	ko00230,ko00983,ko01100,ko01110,ko01130,ko03008,map00230,map00983,map01100,map01110,map01130,map03008	M00049	R00127,R00426,R00720,R01547,R01855,R02100,R02720,R03531,R08243	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Ham1p_like
SRR25158456_k127_1264591_13	795955.AFRW01000071_gene534	1.663e-05	51.0	COG5662@1|root,COG5662@2|Bacteria,2IRFU@201174|Actinobacteria,1WA24@1268|Micrococcaceae	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158456_k127_1264591_2	378806.STAUR_4594	1.474e-58	212.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1264591_12	1123261.AXDW01000007_gene2295	7.548e-06	57.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,1RP0P@1236|Gammaproteobacteria,1X5D4@135614|Xanthomonadales	135614|Xanthomonadales	O	Tellurite resistance protein TerB	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
SRR25158456_k127_1264591_6	118163.Ple7327_2433	2.268e-25	117.0	COG4293@1|root,COG4293@2|Bacteria,1G555@1117|Cyanobacteria,3VJTM@52604|Pleurocapsales	1117|Cyanobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158456_k127_1264591_5	686340.Metal_0100	3.285e-26	112.0	COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158456_k127_1264591_9	665956.HMPREF1032_03571	1.11e-11	76.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3WJZD@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158456_k127_1264591_7	522373.Smlt3869	1.486e-23	117.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,1S7AR@1236|Gammaproteobacteria,1XC4W@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158456_k127_1264591_0	1125863.JAFN01000001_gene2900	2.324e-124	434.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_1264591_3	1379270.AUXF01000001_gene2636	1.101e-32	145.0	COG0553@1|root,COG0553@2|Bacteria,1ZUB8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
SRR25158456_k127_1264591_1	379066.GAU_2720	2.1e-99	361.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SRR25158456_k127_1264591_10	1047013.AQSP01000028_gene2076	8.795e-09	68.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
SRR25158456_k127_1264591_14	999141.GME_07704	0.0007985	50.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1XMA4@135619|Oceanospirillales	135619|Oceanospirillales	NU	Tfp pilus assembly protein PilE	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
SRR25158456_k127_1264591_8	1121920.AUAU01000011_gene151	3.939e-14	78.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	2.4.1.21	ko:K00703,ko:K02237,ko:K02238	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00429,M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02044	3.A.11.1,3.A.11.2	GT5	-	HHH_3,PLDc_2,SLBB
SRR25158456_k127_1268770_1	379066.GAU_0215	1.998e-30	132.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158456_k127_1268770_0	1158602.I590_03017	3.374e-32	139.0	COG0616@1|root,COG0616@2|Bacteria,1U2Z9@1239|Firmicutes,4HQWF@91061|Bacilli	91061|Bacilli	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
SRR25158456_k127_1268770_2	1173028.ANKO01000155_gene4501	4.089e-10	73.0	COG1672@1|root,COG2114@1|root,COG1672@2|Bacteria,COG2114@2|Bacteria,1G0F4@1117|Cyanobacteria,1H73P@1150|Oscillatoriales	1117|Cyanobacteria	KLT	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,Guanylate_cyc,TIR_2
SRR25158456_k127_1268770_3	658187.LDG_5840	0.0001046	54.0	COG2067@1|root,COG2067@2|Bacteria,1PIEF@1224|Proteobacteria,1T9KI@1236|Gammaproteobacteria,1JE3I@118969|Legionellales	118969|Legionellales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
SRR25158456_k127_1268770_4	96561.Dole_0842	0.0003048	51.0	COG3209@1|root,COG3386@1|root,COG3209@2|Bacteria,COG3386@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2MN6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
SRR25158456_k127_1282705_2	448385.sce7182	1.197e-89	301.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,42W6K@68525|delta/epsilon subdivisions,2WS34@28221|Deltaproteobacteria,2YZXI@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158456_k127_1282705_0	1121015.N789_12435	6.994e-144	499.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1X4SZ@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
SRR25158456_k127_1282705_3	204669.Acid345_1437	1.033e-65	233.0	COG4200@1|root,COG4200@2|Bacteria	2|Bacteria	V	ABC-2 family transporter protein	-	-	-	ko:K20460,ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
SRR25158456_k127_1282705_1	760192.Halhy_3635	5.135e-105	348.0	COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,1IUZA@117747|Sphingobacteriia	976|Bacteroidetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K20459	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
SRR25158456_k127_1282705_4	204669.Acid345_1439	1.561e-28	121.0	2EER6@1|root,338IW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
SRR25158456_k127_1282705_5	1116369.KB890024_gene4299	7.647e-26	109.0	COG3655@1|root,COG3655@2|Bacteria,1N6VH@1224|Proteobacteria,2UFAM@28211|Alphaproteobacteria,43Q7Q@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
SRR25158456_k127_1282705_6	1121019.AUMN01000012_gene2408	0.0001283	47.0	COG3668@1|root,COG3668@2|Bacteria,2GRIP@201174|Actinobacteria	201174|Actinobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158456_k127_1283138_0	1101190.ARWB01000001_gene1134	7.189e-113	376.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2U0FE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_3
SRR25158456_k127_1283138_3	1101190.ARWB01000001_gene1135	2.229e-56	208.0	COG0863@1|root,COG0863@2|Bacteria,1R8R3@1224|Proteobacteria,2U3U5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1283138_4	349521.HCH_10021	4.809e-35	141.0	COG3727@1|root,COG3727@2|Bacteria,1RH1C@1224|Proteobacteria,1SFHA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA mismatch endonuclease Vsr	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
SRR25158456_k127_1283138_2	1382303.JPOM01000001_gene1342	1.791e-59	212.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,2KF9T@204458|Caulobacterales	204458|Caulobacterales	EH	Anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158456_k127_1283138_1	404589.Anae109_0374	5.548e-91	318.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria,2YUVG@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
SRR25158456_k127_1288218_1	1123073.KB899242_gene939	1.115e-82	281.0	COG1462@1|root,COG1462@2|Bacteria,1Q8KJ@1224|Proteobacteria,1RU2Q@1236|Gammaproteobacteria,1X6HV@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
SRR25158456_k127_1288218_3	1269813.ATUL01000046_gene1273	4.844e-45	175.0	COG2199@1|root,COG3706@2|Bacteria,1PGAZ@1224|Proteobacteria,1RWZ6@1236|Gammaproteobacteria,1X0SN@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
SRR25158456_k127_1288218_6	498211.CJA_0444	3.397e-11	74.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S27A@1236|Gammaproteobacteria,1FG4Y@10|Cellvibrio	1236|Gammaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158456_k127_1288218_0	290397.Adeh_0058	2.358e-89	320.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SRR25158456_k127_1288218_4	1121459.AQXE01000001_gene2935	1.354e-20	108.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WNT6@28221|Deltaproteobacteria,2MAZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158456_k127_1288218_2	1047013.AQSP01000111_gene1672	1.277e-63	230.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SRR25158456_k127_1292605_10	935845.JADQ01000050_gene3912	1.297e-16	81.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,26SMZ@186822|Paenibacillaceae	91061|Bacilli	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158456_k127_1292605_4	243231.GSU2000	1.13e-69	246.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158456_k127_1292605_9	240015.ACP_2579	2.889e-18	92.0	COG3468@1|root,COG3468@2|Bacteria,3Y4BG@57723|Acidobacteria,2JJ56@204432|Acidobacteriia	204432|Acidobacteriia	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1292605_3	1340493.JNIF01000003_gene1293	3.262e-77	280.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
SRR25158456_k127_1292605_5	215803.DB30_4900	5.876e-65	239.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_1292605_2	292459.STH604	1.346e-77	274.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia	186801|Clostridia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
SRR25158456_k127_1292605_0	1304880.JAGB01000004_gene1468	4.891e-111	375.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia	186801|Clostridia	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
SRR25158456_k127_1292605_1	292459.STH605	3.768e-80	282.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158456_k127_1292605_6	1345697.M493_11715	2.35e-63	225.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1WFMZ@129337|Geobacillus	91061|Bacilli	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	iYO844.BSU35020	Glucosamine_iso
SRR25158456_k127_1292605_8	928724.SacglDRAFT_03544	4.608e-21	104.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158456_k127_1292605_7	365046.Rta_16960	6.265e-63	244.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158456_k127_1292713_1	927677.ALVU02000001_gene4017	1.6e-58	215.0	COG4589@1|root,COG4589@2|Bacteria,1GCQF@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158456_k127_1292713_2	1123060.JONP01000001_gene1305	1.664e-47	191.0	COG0204@1|root,COG0204@2|Bacteria,1RA8V@1224|Proteobacteria,2U5DY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-transferase	plsC	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158456_k127_1292713_0	338963.Pcar_2780	4.232e-190	609.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2WPBS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	agmH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158456_k127_129412_0	1519464.HY22_00255	2.954e-297	937.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_129412_2	1122939.ATUD01000001_gene577	1.174e-58	232.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_129412_7	118168.MC7420_6357	2.676e-10	74.0	COG2730@1|root,COG2931@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,1G314@1117|Cyanobacteria,1HAD6@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Calx-beta,Glyco_hydro_9
SRR25158456_k127_129412_1	1123070.KB899248_gene6	4.112e-84	292.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158456_k127_129412_4	41431.PCC8801_2333	1.086e-52	210.0	COG2132@1|root,COG2132@2|Bacteria,1G2BC@1117|Cyanobacteria,3KGW1@43988|Cyanothece	1117|Cyanobacteria	Q	PFAM multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158456_k127_129412_6	1454004.AW11_01135	4.062e-13	81.0	28XE3@1|root,2ZJBU@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_129412_3	172088.AUGA01000075_gene7042	5.582e-55	216.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria,3JS7C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158456_k127_129412_5	1155714.KB891999_gene67	2.544e-33	144.0	COG1262@1|root,COG1262@2|Bacteria,2I7QU@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_129412_8	68194.JNXR01000022_gene1124	7.983e-10	71.0	COG1075@1|root,COG1075@2|Bacteria,2I090@201174|Actinobacteria	201174|Actinobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
SRR25158456_k127_1296324_3	1125725.HMPREF1325_1927	3.139e-43	165.0	COG1253@1|root,COG1253@2|Bacteria,2J61P@203691|Spirochaetes	203691|Spirochaetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
SRR25158456_k127_1296324_1	756499.Desde_3641	7.331e-84	289.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,2609D@186807|Peptococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158456_k127_1296324_0	1123059.KB823013_gene502	6.382e-225	734.0	COG1629@1|root,COG1629@2|Bacteria,1MVSG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158456_k127_1296324_2	1047013.AQSP01000123_gene1525	5.667e-68	259.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158456_k127_1296324_6	1125863.JAFN01000001_gene2242	7.08e-24	116.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria,42VRN@68525|delta/epsilon subdivisions,2WS04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
SRR25158456_k127_1296324_4	402777.KB235898_gene4933	5.048e-38	143.0	COG4115@1|root,COG4115@2|Bacteria,1G9S6@1117|Cyanobacteria,1HCFP@1150|Oscillatoriales	1117|Cyanobacteria	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
SRR25158456_k127_1296324_5	32057.KB217483_gene9382	5.876e-32	132.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128,2.3.1.82	ko:K00663,ko:K03790	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Acetyltransf_3
SRR25158456_k127_1297515_0	204669.Acid345_1498	2.546e-58	228.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158456_k127_1297515_3	446468.Ndas_3551	6.922e-06	59.0	COG2304@1|root,COG2304@2|Bacteria,2GKDC@201174|Actinobacteria,4EHTV@85012|Streptosporangiales	201174|Actinobacteria	O	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	ADP_ribosyl_GH,DUF3520,VWA,vWF_A
SRR25158456_k127_1297515_4	401053.AciPR4_0693	0.0001521	55.0	COG0810@1|root,COG4219@1|root,COG0810@2|Bacteria,COG4219@2|Bacteria,3Y6JC@57723|Acidobacteria,2JKDS@204432|Acidobacteriia	204432|Acidobacteriia	KMT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
SRR25158456_k127_1297515_5	926569.ANT_03580	0.000541	51.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03580|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1297515_1	700598.Niako_4532	2.25e-10	73.0	COG1807@1|root,COG1807@2|Bacteria,4NXNF@976|Bacteroidetes,1IZJI@117747|Sphingobacteriia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1310371_2	1227487.C474_16769	1.953e-14	73.0	COG5579@1|root,arCOG13395@2157|Archaea,2XXH9@28890|Euryarchaeota,23VTI@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
SRR25158456_k127_1310371_1	1121456.ATVA01000013_gene1130	9.07e-29	131.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158456_k127_1310371_0	278963.ATWD01000002_gene691	4.62e-52	191.0	COG1807@1|root,COG1807@2|Bacteria,3Y383@57723|Acidobacteria,2JIBE@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_1345915_0	1237149.C900_01925	0.0	1200.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,4NDV5@976|Bacteroidetes,47K9U@768503|Cytophagia	976|Bacteroidetes	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NAD_binding_4,PP-binding,Thioesterase,ketoacyl-synt
SRR25158456_k127_1345915_1	1192034.CAP_4402	4.897e-36	157.0	2DYTI@1|root,34B1N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1363409_1	215803.DB30_1187	1.045e-93	325.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria,2YZ41@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158456_k127_1363409_4	555079.Toce_2266	1.535e-51	202.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,24BHT@186801|Clostridia	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158456_k127_1363409_3	903818.KI912268_gene2181	5.167e-74	282.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_1363409_2	1047013.AQSP01000131_gene1840	1.907e-85	308.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158456_k127_1363409_0	28072.Nos7524_0385	1.544e-139	451.0	COG4637@1|root,COG4637@2|Bacteria,1G1CK@1117|Cyanobacteria	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
SRR25158456_k127_1385890_3	1121920.AUAU01000013_gene1734	1.484e-91	307.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	MTS
SRR25158456_k127_1385890_4	1267534.KB906757_gene1077	6.153e-41	159.0	COG5646@1|root,COG5646@2|Bacteria,3Y6CJ@57723|Acidobacteria,2JM3Q@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158456_k127_1385890_1	639030.JHVA01000001_gene3842	1.144e-180	580.0	COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria,2JHR4@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_1385890_2	204669.Acid345_0621	8.58e-145	496.0	COG0612@1|root,COG0612@2|Bacteria,3Y322@57723|Acidobacteria,2JP25@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16_C
SRR25158456_k127_1385890_0	1304872.JAGC01000003_gene2613	7.217e-204	661.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_1393697_1	1122611.KB903939_gene313	5.954e-76	276.0	COG0515@1|root,COG4403@1|root,COG0515@2|Bacteria,COG4403@2|Bacteria,2H5BJ@201174|Actinobacteria	201174|Actinobacteria	KLT	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158456_k127_1393697_2	1122611.KB903939_gene312	5.957e-37	155.0	28QBS@1|root,2ZCUB@2|Bacteria,2HBTV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1393697_0	502025.Hoch_1577	5.03e-173	575.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158456_k127_1408662_0	404380.Gbem_3508	2.116e-69	244.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158456_k127_1408662_2	204669.Acid345_0060	3.473e-56	207.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158456_k127_1408662_1	1047013.AQSP01000077_gene2269	1.073e-62	225.0	COG0568@1|root,COG0568@2|Bacteria,2NQT5@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158456_k127_1415824_10	1538644.KO02_13555	9.509e-48	191.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1IUE2@117747|Sphingobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1415824_13	760192.Halhy_4445	4.726e-25	112.0	COG4675@1|root,COG4675@2|Bacteria,4NW18@976|Bacteroidetes,1IZUM@117747|Sphingobacteriia	2|Bacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Collar
SRR25158456_k127_1415824_17	420324.KI911963_gene356	3.067e-15	83.0	COG3652@1|root,COG3652@2|Bacteria,1N6QU@1224|Proteobacteria,2UBB9@28211|Alphaproteobacteria,1JZBB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRR25158456_k127_1415824_8	1174528.JH992898_gene2614	6.037e-60	237.0	COG4995@1|root,COG4995@2|Bacteria,1GDW4@1117|Cyanobacteria	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_1415824_7	1174528.JH992898_gene2614	1.47e-64	252.0	COG4995@1|root,COG4995@2|Bacteria,1GDW4@1117|Cyanobacteria	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_1415824_2	765420.OSCT_2362	4.709e-106	369.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,3769V@32061|Chloroflexia	32061|Chloroflexia	S	SMART von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158456_k127_1415824_3	633131.TR2A62_1120	3.64e-105	358.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0714 MoxR-like ATPases	MA20_09400	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158456_k127_1415824_12	1382306.JNIM01000001_gene2450	1.537e-26	124.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158456_k127_1415824_14	309801.trd_0377	2.606e-23	113.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi,27YGN@189775|Thermomicrobia	189775|Thermomicrobia	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158456_k127_1415824_15	536232.CLM_1111	4.215e-23	115.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,36DBJ@31979|Clostridiaceae	186801|Clostridia	H	molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158456_k127_1415824_9	525904.Tter_2236	2.805e-54	204.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158456_k127_1415824_5	479434.Sthe_2775	4.267e-71	260.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2G88Z@200795|Chloroflexi,27YSQ@189775|Thermomicrobia	189775|Thermomicrobia	O	metallochaperone-like domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158456_k127_1415824_11	1047013.AQSP01000139_gene2341	2.77e-37	158.0	COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria	2|Bacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	mocA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3649,iB21_1397.B21_02672,iECABU_c1320.ECABU_c31580,iECBD_1354.ECBD_0860,iECB_1328.ECB_02710,iECD_1391.ECD_02710,iEcHS_1320.EcHS_A3037	HD,HTH_1,NTP_transf_3
SRR25158456_k127_1415824_0	518766.Rmar_2766	0.0	1288.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158456_k127_1415824_6	479434.Sthe_2777	1.995e-70	241.0	COG2080@1|root,COG2080@2|Bacteria,2GBCT@200795|Chloroflexi,27YT4@189775|Thermomicrobia	189775|Thermomicrobia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2_2
SRR25158456_k127_1415824_4	485913.Krac_6955	5.835e-104	345.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158456_k127_1415824_16	7209.EFO20088.2	4.391e-19	98.0	COG1084@1|root,KOG3045@1|root,KOG1490@2759|Eukaryota,KOG3045@2759|Eukaryota,39M2V@33154|Opisthokonta,3BDD6@33208|Metazoa,3CX4G@33213|Bilateria,40AYW@6231|Nematoda,1KUPJ@119089|Chromadorea	33208|Metazoa	S	Involved in the biogenesis of the 60S ribosomal subunit	GTPBP4	GO:0000079,GO:0000166,GO:0000226,GO:0000278,GO:0000280,GO:0000463,GO:0000470,GO:0001882,GO:0001883,GO:0001932,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005730,GO:0005737,GO:0005794,GO:0005829,GO:0006139,GO:0006275,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007162,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008156,GO:0008285,GO:0008340,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009987,GO:0010259,GO:0010467,GO:0010556,GO:0010558,GO:0010605,GO:0010646,GO:0010883,GO:0010888,GO:0012505,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0022402,GO:0022407,GO:0022408,GO:0022607,GO:0022613,GO:0023051,GO:0030155,GO:0030334,GO:0030336,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031647,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0033341,GO:0033342,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040012,GO:0040013,GO:0042127,GO:0042254,GO:0042273,GO:0042325,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045859,GO:0045934,GO:0046483,GO:0046626,GO:0048285,GO:0048471,GO:0048519,GO:0048523,GO:0048583,GO:0048856,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050821,GO:0051052,GO:0051053,GO:0051098,GO:0051100,GO:0051171,GO:0051172,GO:0051174,GO:0051225,GO:0051239,GO:0051246,GO:0051248,GO:0051270,GO:0051271,GO:0051338,GO:0051726,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070925,GO:0071704,GO:0071840,GO:0071900,GO:0080090,GO:0090304,GO:0090307,GO:0097159,GO:0097367,GO:0140014,GO:1900076,GO:1901265,GO:1901360,GO:1901363,GO:1902850,GO:1903047,GO:1903104,GO:1903320,GO:1903321,GO:1904029,GO:1905952,GO:1905953,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000146,GO:2000241	-	ko:K06943	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	NOG1,NOGCT
SRR25158456_k127_1415824_18	604331.AUHY01000064_gene640	0.0001615	53.0	COG1708@1|root,COG1708@2|Bacteria,1WK9Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158456_k127_1415824_1	1283300.ATXB01000002_gene2755	3.668e-273	874.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria,1XG68@135618|Methylococcales	135618|Methylococcales	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1416727_0	706587.Desti_4083	8.202e-237	745.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MQ7V@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
SRR25158456_k127_1416727_3	1125863.JAFN01000001_gene2180	7.02e-73	263.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SRR25158456_k127_1416727_2	1121920.AUAU01000004_gene908	1.259e-73	274.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
SRR25158456_k127_1416727_7	177437.HRM2_02520	3.061e-16	91.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,42PJR@68525|delta/epsilon subdivisions,2WPBQ@28221|Deltaproteobacteria,2MI0V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158456_k127_1416727_1	398767.Glov_0737	1.508e-86	306.0	COG3829@1|root,COG3829@2|Bacteria,1R63H@1224|Proteobacteria,42PJI@68525|delta/epsilon subdivisions,2WK7M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SRR25158456_k127_1416727_8	487796.Flav2ADRAFT_1527	1.735e-15	82.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158456_k127_1416727_6	487796.Flav2ADRAFT_1528	5.956e-20	97.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158456_k127_1416727_5	880073.Calab_1889	7.037e-50	198.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,SSF,SpoIIE
SRR25158456_k127_1416727_4	518766.Rmar_1551	7.267e-59	213.0	COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158456_k127_1416876_3	1396418.BATQ01000141_gene3350	9.287e-33	148.0	COG4676@1|root,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF2135,Plug,VIT,VWA_3
SRR25158456_k127_1416876_1	313606.M23134_06272	5.56e-72	263.0	COG5316@1|root,COG5316@2|Bacteria,4NNBK@976|Bacteroidetes,47TJH@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1416876_2	1123277.KB893239_gene1214	4.72e-69	252.0	COG0627@1|root,COG0627@2|Bacteria,4NIU8@976|Bacteroidetes,47NUH@768503|Cytophagia	976|Bacteroidetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158456_k127_1416876_4	1232410.KI421421_gene3411	2.558e-18	93.0	COG0745@1|root,COG0745@2|Bacteria,1P0HX@1224|Proteobacteria,431WT@68525|delta/epsilon subdivisions,2WWE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158456_k127_1416876_5	1185876.BN8_01866	4.96e-12	74.0	2DMC7@1|root,32J0V@2|Bacteria,4NV5D@976|Bacteroidetes,47QSG@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158456_k127_1416876_0	234267.Acid_2046	0.0	1715.0	COG0642@1|root,COG0745@1|root,COG1511@1|root,COG2770@1|root,COG3437@1|root,COG0745@2|Bacteria,COG1511@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,COG3437@2|Bacteria,3Y6RW@57723|Acidobacteria	57723|Acidobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
SRR25158456_k127_143409_0	502025.Hoch_1367	0.0	3465.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions,2X7UA@28221|Deltaproteobacteria,2Z3KU@29|Myxococcales	28221|Deltaproteobacteria	IQ	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_143409_2	179408.Osc7112_2653	1.849e-44	175.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_4
SRR25158456_k127_1437594_7	497964.CfE428DRAFT_4087	2.185e-05	57.0	COG2010@1|root,COG2010@2|Bacteria,46UZK@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
SRR25158456_k127_1437594_1	1121377.KB906409_gene861	4.523e-87	308.0	COG3662@1|root,COG3662@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158456_k127_1437594_4	1385515.N791_12680	8.271e-53	203.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158456_k127_1437594_3	404589.Anae109_0937	3.346e-68	243.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
SRR25158456_k127_1437594_2	404589.Anae109_0938	3.247e-83	287.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158456_k127_1437594_5	395961.Cyan7425_4389	1.935e-28	118.0	COG3695@1|root,COG3695@2|Bacteria,1G82G@1117|Cyanobacteria	1117|Cyanobacteria	L	Methylated dna-protein cysteine methyltransferase	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
SRR25158456_k127_1437594_6	118168.MC7420_1664	2.031e-19	91.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HC3P@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_1437594_0	234831.PSM_A3090	0.0	1170.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,1RP38@1236|Gammaproteobacteria,2Q0BE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158456_k127_1446329_2	760568.Desku_1720	2.652e-62	223.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,2613M@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158456_k127_1446329_0	234267.Acid_4352	2.308e-121	406.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
SRR25158456_k127_1446329_4	521674.Plim_0071	2.149e-11	76.0	COG0170@1|root,COG0170@2|Bacteria,2J1H5@203682|Planctomycetes	203682|Planctomycetes	I	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1446329_3	1229172.JQFA01000005_gene156	1.05e-31	141.0	COG1836@1|root,COG1836@2|Bacteria,1G07R@1117|Cyanobacteria,1H720@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Integral membrane protein DUF92	-	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	DUF92
SRR25158456_k127_1446329_1	997346.HMPREF9374_0445	2.102e-112	397.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,27BMY@186824|Thermoactinomycetaceae	91061|Bacilli	S	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158456_k127_1468959_11	379066.GAU_3452	6.227e-26	126.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1ZV3U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
SRR25158456_k127_1468959_0	272568.GDI2815	1.546e-251	795.0	COG0272@1|root,COG0507@1|root,COG0272@2|Bacteria,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,2JX0B@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158456_k127_1468959_7	883126.HMPREF9710_04258	4.094e-41	161.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VQ5C@28216|Betaproteobacteria,476ME@75682|Oxalobacteraceae	28216|Betaproteobacteria	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158456_k127_1468959_4	234267.Acid_2196	1.426e-87	303.0	COG2972@1|root,COG2972@2|Bacteria,3Y4IB@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158456_k127_1468959_2	861299.J421_1364	1.047e-122	405.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF418
SRR25158456_k127_1468959_6	929556.Solca_0662	3.066e-43	162.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158456_k127_1468959_1	380358.XALC_2928	1.99e-181	577.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1X4AD@135614|Xanthomonadales	135614|Xanthomonadales	G	sorbosone dehydrogenase	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158456_k127_1468959_10	1041139.KB902724_gene4096	5.084e-33	134.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria,4BBAJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,DUF4437
SRR25158456_k127_1468959_14	1499967.BAYZ01000195_gene3091	1.686e-11	78.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Sortilin-Vps10
SRR25158456_k127_1468959_13	1121957.ATVL01000010_gene431	4.272e-14	76.0	298NJ@1|root,2ZVT4@2|Bacteria,4NM57@976|Bacteroidetes,47KXW@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1468959_15	1033802.SSPSH_001876	2.085e-09	61.0	2DCIK@1|root,2ZEA0@2|Bacteria,1P538@1224|Proteobacteria,1SWFG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1468959_8	1121405.dsmv_3342	3.531e-36	141.0	COG1487@1|root,COG1487@2|Bacteria,1NAWB@1224|Proteobacteria,42ZRS@68525|delta/epsilon subdivisions,2WV1Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158456_k127_1468959_3	1121468.AUBR01000001_gene479	1.944e-94	331.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,42FJE@68295|Thermoanaerobacterales	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
SRR25158456_k127_1468959_5	867845.KI911784_gene1260	4.335e-83	295.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
SRR25158456_k127_1468959_9	645991.Sgly_3341	1.501e-35	141.0	2DQF9@1|root,336H4@2|Bacteria,1VJH7@1239|Firmicutes,2541D@186801|Clostridia,265YM@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1468959_12	1173023.KE650771_gene4994	9.793e-19	97.0	COG4976@1|root,COG4976@2|Bacteria,1G290@1117|Cyanobacteria,1JJRS@1189|Stigonemataceae	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158456_k127_1472456_8	460265.Mnod_0281	1.111e-95	323.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U3XH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,HemolysinCabind
SRR25158456_k127_1472456_5	401053.AciPR4_2317	8.655e-129	444.0	COG2132@1|root,COG2132@2|Bacteria,3Y65V@57723|Acidobacteria,2JMCT@204432|Acidobacteriia	204432|Acidobacteriia	Q	PFAM multicopper oxidase type 2	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158456_k127_1472456_22	1206720.BAFQ01000190_gene4920	6.454e-27	125.0	COG2312@1|root,COG2312@2|Bacteria,2GUAJ@201174|Actinobacteria,4FZYE@85025|Nocardiaceae	201174|Actinobacteria	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
SRR25158456_k127_1472456_1	215803.DB30_3143	4.069e-221	706.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2YTY6@29|Myxococcales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SRR25158456_k127_1472456_13	1384056.N787_09430	5.522e-68	245.0	COG2227@1|root,COG2227@2|Bacteria,1REWV@1224|Proteobacteria,1T1J3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	methyltransferase	ubiG3	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158456_k127_1472456_3	861299.J421_0838	2.968e-158	514.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1ZV6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158456_k127_1472456_2	1120956.JHZK01000014_gene1747	4.922e-185	608.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JN4S@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158456_k127_1472456_0	1125863.JAFN01000001_gene1462	0.0	1019.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158456_k127_1472456_25	1123256.KB907926_gene987	1.472e-13	72.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158456_k127_1472456_14	246197.MXAN_3426	5.677e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2X520@28221|Deltaproteobacteria,2Z004@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRR25158456_k127_1472456_24	1499967.BAYZ01000077_gene862	3.167e-17	97.0	COG1262@1|root,COG2944@1|root,COG5635@1|root,COG1262@2|Bacteria,COG2944@2|Bacteria,COG5635@2|Bacteria,2NR8B@2323|unclassified Bacteria	2|Bacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,FGE-sulfatase,HTH_3,NACHT,TIR_2
SRR25158456_k127_1472456_6	640511.BC1002_1278	3.339e-104	374.0	COG1262@1|root,COG2319@1|root,COG1262@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,1K773@119060|Burkholderiaceae	28216|Betaproteobacteria	S	WD40 repeats	-	-	-	ko:K20332	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
SRR25158456_k127_1472456_15	1267535.KB906767_gene3879	6.235e-55	203.0	COG2846@1|root,COG2846@2|Bacteria,3Y4SU@57723|Acidobacteria,2JMU3@204432|Acidobacteriia	204432|Acidobacteriia	D	Domain of Unknown function (DUF542)	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
SRR25158456_k127_1472456_26	378806.STAUR_7642	2.148e-12	80.0	COG3325@1|root,COG3325@2|Bacteria,1RI4Q@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
SRR25158456_k127_1472456_29	990073.ATHU01000001_gene1045	9.516e-05	52.0	COG1396@1|root,COG1396@2|Bacteria,1R1S2@1224|Proteobacteria,4316J@68525|delta/epsilon subdivisions,2YSDD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
SRR25158456_k127_1472456_17	1192034.CAP_3960	2.428e-40	160.0	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,43ACX@68525|delta/epsilon subdivisions,2X5SX@28221|Deltaproteobacteria	1224|Proteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_1472456_28	1961.JOAK01000007_gene4225	1.546e-06	60.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
SRR25158456_k127_1472456_23	1499967.BAYZ01000104_gene3712	1.287e-23	116.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158456_k127_1472456_12	1499967.BAYZ01000105_gene3475	6.286e-73	262.0	28UH1@1|root,2ZGMU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SRR25158456_k127_1472456_9	1121920.AUAU01000022_gene2489	1.529e-93	330.0	COG2201@1|root,COG2201@2|Bacteria,3Y35K@57723|Acidobacteria	57723|Acidobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SRR25158456_k127_1472456_10	1242864.D187_000271	1.373e-87	298.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2YX13@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
SRR25158456_k127_1472456_19	483219.LILAB_28380	6.026e-32	131.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42TN2@68525|delta/epsilon subdivisions,2WR0G@28221|Deltaproteobacteria,2Z094@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SRR25158456_k127_1472456_11	207559.Dde_1627	1.06e-83	314.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M99S@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
SRR25158456_k127_1472456_4	290397.Adeh_0603	7.308e-136	461.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42Y7C@68525|delta/epsilon subdivisions,2WTJH@28221|Deltaproteobacteria,2YXEJ@29|Myxococcales	28221|Deltaproteobacteria	NT	Chemotaxis protein histidine kinase and related kinases	cheA2	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158456_k127_1472456_20	290397.Adeh_0604	9.607e-31	136.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,42THA@68525|delta/epsilon subdivisions,2WNG6@28221|Deltaproteobacteria,2Z32W@29|Myxococcales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
SRR25158456_k127_1472456_21	269799.Gmet_2303	1.03e-27	125.0	COG2203@1|root,COG2203@2|Bacteria,1NZAZ@1224|Proteobacteria,430KJ@68525|delta/epsilon subdivisions,2WVQM@28221|Deltaproteobacteria,43W14@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1472456_16	290397.Adeh_0606	6.372e-46	173.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria,2Z0DC@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
SRR25158456_k127_1472456_7	1163617.SCD_n02290	7.124e-99	339.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
SRR25158456_k127_1475070_4	1089550.ATTH01000001_gene816	2.991e-53	203.0	COG0700@1|root,COG0700@2|Bacteria,4PM62@976|Bacteroidetes,1FJ72@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleoside recognition	-	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
SRR25158456_k127_1475070_1	1408422.JHYF01000014_gene260	4.859e-58	227.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,36E11@31979|Clostridiaceae	186801|Clostridia	S	Spore maturation protein	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
SRR25158456_k127_1475070_0	1267534.KB906754_gene3807	1.221e-65	246.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	7TMR-DISM_7TM,HAMP,Peripla_BP_3,SpoIIE
SRR25158456_k127_1475070_2	1196322.A370_04095	4.405e-57	216.0	COG0500@1|root,COG2226@2|Bacteria,1U5XV@1239|Firmicutes,24A44@186801|Clostridia,36HFC@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158456_k127_1475070_3	234267.Acid_5304	6.733e-55	200.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
SRR25158456_k127_1480346_0	391037.Sare_1293	6.445e-95	323.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,4DG8W@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
SRR25158456_k127_1480346_10	287986.DV20_13830	0.0002306	49.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4DYMB@85010|Pseudonocardiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158456_k127_1480346_8	1189612.A33Q_1894	7.518e-05	53.0	COG1426@1|root,COG1426@2|Bacteria,4PM8V@976|Bacteroidetes	976|Bacteroidetes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158456_k127_1480346_7	1172180.KB911778_gene5157	1.603e-05	57.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C
SRR25158456_k127_1480346_9	930169.B5T_01296	0.0001056	49.0	COG1476@1|root,COG1476@2|Bacteria,1NPDH@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158456_k127_1480346_1	756067.MicvaDRAFT_1415	3.244e-87	297.0	COG2189@1|root,COG2189@2|Bacteria,1G4HB@1117|Cyanobacteria,1HFQ8@1150|Oscillatoriales	1117|Cyanobacteria	H	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158456_k127_1480346_12	204669.Acid345_2427	0.0005282	50.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158456_k127_1480346_13	926556.Echvi_1081	0.0007178	51.0	2EPF2@1|root,33H1Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1480346_5	1117319.PSPO_12507	2.413e-08	64.0	2FERS@1|root,346QU@2|Bacteria,1P2X0@1224|Proteobacteria,1ST17@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1480346_4	1267535.KB906767_gene2939	1.355e-33	139.0	COG3764@1|root,COG3764@2|Bacteria,3Y5NI@57723|Acidobacteria,2JNIT@204432|Acidobacteriia	204432|Acidobacteriia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158456_k127_1480346_11	290397.Adeh_4027	0.0002642	54.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158456_k127_1480346_2	526225.Gobs_2552	2.206e-58	210.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria,4EUWH@85013|Frankiales	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, middle domain	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
SRR25158456_k127_1481137_6	1121127.JAFA01000006_gene5612	0.0005208	49.0	2FD52@1|root,34579@2|Bacteria,1P2Y8@1224|Proteobacteria,2W4EM@28216|Betaproteobacteria,1K9FM@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158456_k127_1481137_4	391595.RLO149_c028240	3.016e-10	63.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,2VBT7@28211|Alphaproteobacteria,2P54U@2433|Roseobacter	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158456_k127_1481137_5	717785.HYPMC_4690	1.305e-08	59.0	2DGI2@1|root,2ZW2M@2|Bacteria,1P4XI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1481137_2	240015.ACP_2661	3.52e-85	298.0	COG3677@1|root,COG3677@2|Bacteria,3Y5PF@57723|Acidobacteria,2JK2Q@204432|Acidobacteriia	204432|Acidobacteriia	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158456_k127_1481137_0	1173022.Cri9333_3496	1.853e-176	571.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_1481137_3	156889.Mmc1_2431	1.226e-81	284.0	COG0438@1|root,COG0438@2|Bacteria,1PE8X@1224|Proteobacteria,2UAV8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	amsK	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_1481137_1	234267.Acid_1188	1.368e-128	431.0	COG1835@1|root,COG1835@2|Bacteria,3Y5EG@57723|Acidobacteria	57723|Acidobacteria	I	PFAM acyltransferase 3	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158456_k127_1487020_1	1123242.JH636434_gene4587	5.85e-91	310.0	COG0367@1|root,COG0367@2|Bacteria,2IXAI@203682|Planctomycetes	203682|Planctomycetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_1487020_2	1242864.D187_009162	1.377e-49	192.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2YXW5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_1487020_0	314278.NB231_08420	1.718e-104	348.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_1493_0	243231.GSU2278	2.272e-123	407.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,43U2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158456_k127_1493_1	234267.Acid_6233	7.236e-51	199.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158456_k127_1493_2	1177928.TH2_07856	2.753e-33	138.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,2JS96@204441|Rhodospirillales	204441|Rhodospirillales	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158456_k127_1493_3	1089550.ATTH01000001_gene729	5.467e-20	102.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158456_k127_1493824_6	926560.KE387023_gene3374	3.68e-23	109.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_1493824_5	382464.ABSI01000013_gene1538	1.56e-35	143.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158456_k127_1493824_7	1340493.JNIF01000004_gene616	2.638e-21	108.0	COG4219@1|root,COG4219@2|Bacteria,3Y63E@57723|Acidobacteria	57723|Acidobacteria	KT	Protein of unknown function (DUF3738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738,Peptidase_M56
SRR25158456_k127_1493824_8	56780.SYN_01772	1.625e-10	74.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2MQHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Secretin and TonB N terminus short domain	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158456_k127_1493824_2	867900.Celly_0996	1.415e-126	417.0	COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1493824_1	479433.Caci_6353	2.245e-260	817.0	COG0644@1|root,COG0644@2|Bacteria,2GIWW@201174|Actinobacteria	201174|Actinobacteria	C	halogenase	-	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
SRR25158456_k127_1493824_3	1144275.COCOR_03854	2.738e-115	386.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,42SJE@68525|delta/epsilon subdivisions,2WPS5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	dioxygenase	-	-	1.13.11.75	ko:K00464	-	-	R09601	RC00912	ko00000,ko01000	-	-	-	RPE65,TAT_signal
SRR25158456_k127_1493824_0	443255.SCLAV_p1350	0.0	1317.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	ko:K13611,ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01004,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_1493824_4	449447.MAE_12770	1.649e-43	163.0	COG0824@1|root,COG0824@2|Bacteria,1GDHP@1117|Cyanobacteria	1117|Cyanobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K15315	ko01059,map01059	-	R11436	RC00039,RC03437	ko00000,ko00001,ko01008	-	-	-	4HBT_2
SRR25158456_k127_1494250_0	379066.GAU_2504	1.289e-79	292.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1494250_2	926550.CLDAP_27260	4.698e-36	143.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158456_k127_1494250_1	443143.GM18_3425	1.998e-42	179.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
SRR25158456_k127_1494250_4	1217718.ALOU01000043_gene4012	6.325e-05	49.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria,1K92I@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158456_k127_1494250_3	1121272.KB903250_gene2798	7.281e-30	128.0	COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
SRR25158456_k127_1496986_2	1123257.AUFV01000001_gene1520	1.596e-24	115.0	COG5492@1|root,COG5492@2|Bacteria,1PBEQ@1224|Proteobacteria	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1496986_1	522306.CAP2UW1_3032	2.409e-114	375.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VJXG@28216|Betaproteobacteria,1KQJK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158456_k127_1496986_4	1380356.JNIK01000015_gene2533	1.633e-11	76.0	COG4235@1|root,COG4235@2|Bacteria,2IEIE@201174|Actinobacteria	201174|Actinobacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1496986_6	1121272.KB903249_gene2169	0.0008289	53.0	COG2373@1|root,COG2374@1|root,COG3250@1|root,COG5492@1|root,COG2373@2|Bacteria,COG2374@2|Bacteria,COG3250@2|Bacteria,COG5492@2|Bacteria,2I2E0@201174|Actinobacteria,4DF33@85008|Micromonosporales	201174|Actinobacteria	E	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
SRR25158456_k127_1496986_3	452637.Oter_4618	1.198e-13	85.0	COG3391@1|root,COG3391@2|Bacteria,46UA2@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3,NHL
SRR25158456_k127_1496986_0	56780.SYN_01564	4.967e-150	496.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MQ69@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_1496986_5	1121434.AULY01000006_gene611	1.775e-09	61.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2M8K0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR25158456_k127_1497242_4	861299.J421_0949	5.933e-54	215.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_0949|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1497242_1	1123248.KB893327_gene788	1.152e-100	334.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158456_k127_1497242_7	391612.CY0110_27465	2.127e-12	71.0	COG2361@1|root,COG2361@2|Bacteria,1G7PD@1117|Cyanobacteria,3KIUT@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158456_k127_1497242_6	388467.A19Y_0305	7.269e-28	115.0	COG1669@1|root,COG1669@2|Bacteria,1G8GD@1117|Cyanobacteria,1HCDB@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158456_k127_1497242_3	1429916.X566_23760	1.078e-58	213.0	COG0438@1|root,COG0438@2|Bacteria,1PJ7G@1224|Proteobacteria,2U2TC@28211|Alphaproteobacteria,3JVKZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158456_k127_1497242_5	877424.ATWC01000006_gene328	3.014e-47	180.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_1497242_2	290397.Adeh_3057	7.426e-90	324.0	COG0438@1|root,COG0438@2|Bacteria,1PEGM@1224|Proteobacteria,43AEB@68525|delta/epsilon subdivisions,2X5U6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_1497242_0	489825.LYNGBM3L_15880	5.537e-198	631.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1497926_0	1267533.KB906733_gene3108	4.383e-23	117.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158456_k127_1503113_2	861299.J421_0942	2.246e-32	136.0	COG0003@1|root,COG0003@2|Bacteria,1ZVAB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158456_k127_1503113_3	1173025.GEI7407_1660	0.0001367	48.0	2E38Y@1|root,32Y8N@2|Bacteria,1G95Q@1117|Cyanobacteria,1HCUC@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Gas vesicle protein G	gvpG	-	-	-	-	-	-	-	-	-	-	-	GvpG
SRR25158456_k127_1503113_0	861299.J421_0944	7.711e-96	325.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158456_k127_1503113_1	448385.sce3935	5e-73	258.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRR25158456_k127_150583_7	927677.ALVU02000001_gene1427	1.691e-28	132.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H4T7@1142|Synechocystis	1117|Cyanobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
SRR25158456_k127_150583_6	477641.MODMU_4926	2.166e-33	142.0	COG0265@1|root,COG0265@2|Bacteria,2IJFX@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_150583_5	1454004.AW11_00750	2.55e-35	157.0	COG0457@1|root,COG0457@2|Bacteria,1N4XB@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
SRR25158456_k127_150583_1	404589.Anae109_1229	1.318e-181	578.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,42M4F@68525|delta/epsilon subdivisions,2WKK3@28221|Deltaproteobacteria,2Z320@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158456_k127_150583_2	886293.Sinac_6462	1.408e-156	502.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158456_k127_150583_3	1121405.dsmv_3246	1.137e-65	238.0	COG0472@1|root,COG1086@1|root,COG0472@2|Bacteria,COG1086@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2X5IH@28221|Deltaproteobacteria,2MQ3P@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
SRR25158456_k127_150583_4	663610.JQKO01000010_gene2107	4.555e-63	240.0	29Y07@1|root,30JT3@2|Bacteria,1QBEW@1224|Proteobacteria,2UZ5N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_150583_0	1173027.Mic7113_5255	3.639e-216	684.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_1510244_6	234267.Acid_6263	6.529e-95	343.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_1510244_12	1444711.CCJF01000005_gene259	1.427e-59	218.0	COG0564@1|root,COG0564@2|Bacteria,2JG28@204428|Chlamydiae	204428|Chlamydiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158456_k127_1510244_13	1283284.AZUK01000001_gene1414	2.762e-58	223.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RSAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,Response_reg
SRR25158456_k127_1510244_2	1385510.N781_08120	3.261e-145	498.0	COG1502@1|root,COG1502@2|Bacteria,1VSU5@1239|Firmicutes,4HTP4@91061|Bacilli,2Y9A5@289201|Pontibacillus	91061|Bacilli	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,PLDc_2
SRR25158456_k127_1510244_4	1123258.AQXZ01000018_gene1010	4.961e-128	428.0	COG3848@1|root,COG3848@2|Bacteria,2IE61@201174|Actinobacteria	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
SRR25158456_k127_1510244_10	68223.JNZY01000062_gene1107	5.519e-65	251.0	COG0574@1|root,COG0574@2|Bacteria,2IJCV@201174|Actinobacteria	201174|Actinobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
SRR25158456_k127_1510244_11	1192034.CAP_7843	6.064e-61	238.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,43CQD@68525|delta/epsilon subdivisions,2X7XQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_1510244_5	1340493.JNIF01000003_gene2877	2.083e-97	329.0	COG0666@1|root,COG0666@2|Bacteria,3Y6UE@57723|Acidobacteria	57723|Acidobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2
SRR25158456_k127_1510244_1	1125863.JAFN01000001_gene824	8.734e-185	584.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42MWV@68525|delta/epsilon subdivisions,2WJJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24
SRR25158456_k127_1510244_3	1282360.ABAC460_22805	2.423e-128	425.0	COG0520@1|root,COG0520@2|Bacteria,1NRXE@1224|Proteobacteria	1224|Proteobacteria	E	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Methyltransf_25
SRR25158456_k127_1510244_17	1282360.ABAC460_22800	3.321e-30	126.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.7.7.80,2.8.1.1,2.8.1.11	ko:K02439,ko:K21147	ko00920,ko01110,ko01120,ko04122,map00920,map01110,map01120,map04122	-	R01931,R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158456_k127_1510244_14	1282360.ABAC460_22795	3.579e-58	216.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2U4F1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158456_k127_1510244_16	1282360.ABAC460_22790	5.069e-41	161.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria	1224|Proteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158456_k127_1510244_7	1282360.ABAC460_22785	4.176e-76	266.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2U25R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158456_k127_1510244_9	1532557.JL37_18845	5.33e-68	233.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2VRD1@28216|Betaproteobacteria,3T7K6@506|Alcaligenaceae	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158456_k127_1510244_15	94624.Bpet2934	1.447e-41	156.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VU64@28216|Betaproteobacteria,3T4WD@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRR25158456_k127_1510244_0	345341.KUTG_06354	2.02e-188	595.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DXRK@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1510244_8	419610.Mext_1945	5.455e-75	259.0	COG4262@1|root,COG4262@2|Bacteria,1P1G3@1224|Proteobacteria,2TQSR@28211|Alphaproteobacteria,1JR09@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Spermidine synthase	MA20_16695	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158456_k127_1510244_18	1121438.JNJA01000018_gene3310	9.82e-14	72.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,43BMJ@68525|delta/epsilon subdivisions,2WUEV@28221|Deltaproteobacteria,2MH9E@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K20973	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_4,Response_reg
SRR25158456_k127_1512132_3	903818.KI912268_gene1372	1.625e-51	203.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158456_k127_1512132_2	1128421.JAGA01000001_gene2399	4.535e-165	527.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4620	FAA_hydrolase,FAA_hydrolase_N
SRR25158456_k127_1512132_4	1382359.JIAL01000001_gene714	3.98e-46	171.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria,2JMV1@204432|Acidobacteriia	204432|Acidobacteriia	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1512132_5	234267.Acid_6517	5.269e-13	80.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria	57723|Acidobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1512132_0	1123073.KB899241_gene2101	1.702e-199	629.0	COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,1RQG2@1236|Gammaproteobacteria,1X40V@135614|Xanthomonadales	135614|Xanthomonadales	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158456_k127_1512132_1	204669.Acid345_2004	1.321e-170	542.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158456_k127_152117_3	385682.AFSL01000082_gene1172	3.912e-36	145.0	2E5ZM@1|root,330P1@2|Bacteria,4NY5P@976|Bacteroidetes,2FVVG@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_152117_1	452637.Oter_0067	5.525e-64	243.0	COG3279@1|root,COG3279@2|Bacteria,46VCX@74201|Verrucomicrobia,3KA2E@414999|Opitutae	2|Bacteria	K	PFAM response regulator receiver	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	EAL,HATPase_c,HisKA,LytTR,Response_reg
SRR25158456_k127_152117_2	1254432.SCE1572_26545	1.123e-57	214.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158456_k127_152117_0	401053.AciPR4_3595	1.738e-172	553.0	COG0535@1|root,COG0535@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158456_k127_152117_5	765177.Desmu_1288	1.629e-09	67.0	COG0500@1|root,arCOG01631@2157|Archaea,2XQ7P@28889|Crenarchaeota	28889|Crenarchaeota	Q	RNA methylase	-	GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	CMAS,DOT1,Methyltransf_25,Methyltransf_31,PrmA
SRR25158456_k127_152117_4	395965.Msil_3211	7.332e-16	81.0	COG1942@1|root,COG1942@2|Bacteria,1RHA5@1224|Proteobacteria,2U7NN@28211|Alphaproteobacteria,3NBAZ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Tautomerase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
SRR25158456_k127_1527424_3	1267534.KB906755_gene4691	1.717e-75	260.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_1527424_2	1234664.AMRO01000024_gene1941	4.767e-95	320.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158456_k127_1527424_1	383372.Rcas_3207	6.329e-113	405.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2G8HW@200795|Chloroflexi,376W0@32061|Chloroflexia	32061|Chloroflexia	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158456_k127_1527424_4	383372.Rcas_3208	1.359e-31	140.0	COG4995@1|root,COG4995@2|Bacteria,2G903@200795|Chloroflexi,377ZS@32061|Chloroflexia	32061|Chloroflexia	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_1527424_0	1121920.AUAU01000029_gene1394	3.167e-139	457.0	COG1972@1|root,COG1972@2|Bacteria,3Y2KI@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
SRR25158456_k127_1529832_1	926560.KE387026_gene4177	1.049e-88	297.0	COG2197@1|root,COG2197@2|Bacteria,1WM1U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158456_k127_1529832_0	215803.DB30_4862	4.013e-93	320.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YWC2@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158456_k127_1530247_0	204669.Acid345_3117	1.691e-153	506.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria,2JI6E@204432|Acidobacteriia	204432|Acidobacteriia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158456_k127_1530247_1	861299.J421_1634	7.456e-89	306.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158456_k127_1532572_9	290397.Adeh_3692	6.482e-33	145.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158456_k127_1532572_11	204669.Acid345_2026	6.289e-28	120.0	COG1437@1|root,COG1437@2|Bacteria,3Y4V3@57723|Acidobacteria,2JJIG@204432|Acidobacteriia	204432|Acidobacteriia	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
SRR25158456_k127_1532572_3	401526.TcarDRAFT_0688	3.16e-112	376.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes	909932|Negativicutes	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK,TIM
SRR25158456_k127_1532572_1	370438.PTH_1007	4.867e-134	441.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,260VU@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158456_k127_1532572_4	485916.Dtox_1186	1.593e-111	369.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,260GP@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158456_k127_1532572_12	1242864.D187_000707	3.5e-23	117.0	COG3251@1|root,COG3251@2|Bacteria,1PIM5@1224|Proteobacteria,434YY@68525|delta/epsilon subdivisions,2X933@28221|Deltaproteobacteria,2Z1NR@29|Myxococcales	28221|Deltaproteobacteria	S	MbtH-like protein	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH
SRR25158456_k127_1532572_5	861299.J421_0915	6.024e-101	361.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_1532572_2	861299.J421_0916	4.909e-124	410.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_1532572_8	671143.DAMO_2311	1.828e-66	235.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
SRR25158456_k127_1532572_6	643648.Slip_0136	2.226e-98	331.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42JSG@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158456_k127_1532572_7	316274.Haur_3460	1.902e-81	281.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158456_k127_1532572_0	671143.DAMO_0850	5.264e-175	571.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SRR25158456_k127_1532572_10	1158050.KB895456_gene2121	4.785e-28	133.0	COG1984@1|root,COG2049@1|root,COG1984@2|Bacteria,COG2049@2|Bacteria,2GITH@201174|Actinobacteria,1W89A@1268|Micrococcaceae	201174|Actinobacteria	E	Allophanate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B,CT_C_D
SRR25158456_k127_1532572_13	926566.Terro_4190	3.578e-07	62.0	COG2304@1|root,COG2304@2|Bacteria,3Y74U@57723|Acidobacteria,2JKUC@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1537589_1	1242864.D187_005109	2.545e-78	278.0	COG0477@1|root,COG2814@2|Bacteria,1QRUM@1224|Proteobacteria,42MFJ@68525|delta/epsilon subdivisions,2X2AQ@28221|Deltaproteobacteria,2Z25Q@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158456_k127_1537589_5	382464.ABSI01000005_gene1106	1.4e-33	139.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158456_k127_1537589_4	1340493.JNIF01000003_gene2174	1.083e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,3Y7Z3@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1537589_2	1158345.JNLL01000001_gene1385	8.082e-56	204.0	COG0663@1|root,COG0663@2|Bacteria,2G3ZR@200783|Aquificae	200783|Aquificae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158456_k127_1537589_0	1122216.AUHW01000012_gene1521	6.664e-195	624.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4H32N@909932|Negativicutes	909932|Negativicutes	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
SRR25158456_k127_1540198_2	204669.Acid345_0197	4.162e-172	557.0	28JU0@1|root,2Z9J3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1540198_0	909663.KI867150_gene2817	1.289e-228	730.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42R0A@68525|delta/epsilon subdivisions,2WMYR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DNA_pol_A_exo1,Helicase_C
SRR25158456_k127_1540198_1	629265.PMA4326_06400	3.373e-179	586.0	COG1135@1|root,COG1135@2|Bacteria,1N323@1224|Proteobacteria,1RR2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	P-loop Domain of unknown function (DUF2791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2791
SRR25158456_k127_1540198_3	1120934.KB894431_gene6383	2.886e-119	422.0	COG4103@1|root,COG4103@2|Bacteria,2IJQ0@201174|Actinobacteria,4E89E@85010|Pseudonocardiales	201174|Actinobacteria	S	TerB N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TerB,TerB_C,TerB_N
SRR25158456_k127_1540198_5	1869.MB27_38140	2.089e-23	118.0	29W88@1|root,30HTI@2|Bacteria,2GZVV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1540198_6	196490.AUEZ01000058_gene1085	6.547e-05	45.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,3JQNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
SRR25158456_k127_1540198_4	1267535.KB906767_gene468	1.179e-92	316.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y3SU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158456_k127_1540623_1	861299.J421_2109	1.219e-84	296.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158456_k127_1540623_0	743719.PaelaDRAFT_5830	1.589e-104	367.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26QN5@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB1	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158456_k127_1540623_3	1499967.BAYZ01000028_gene1318	4.104e-48	184.0	COG0739@1|root,COG0739@2|Bacteria,2NPG3@2323|unclassified Bacteria	2|Bacteria	M	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158456_k127_1540623_2	290397.Adeh_1552	1.684e-64	223.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2YV1R@29|Myxococcales	28221|Deltaproteobacteria	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRR25158456_k127_1540623_5	1167006.UWK_02084	8.66e-20	96.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2MJX0@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase M22 glycoprotease	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158456_k127_1540623_4	338966.Ppro_2631	4.739e-25	109.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,43V7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158456_k127_1542895_5	1121422.AUMW01000031_gene3036	9.585e-16	85.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158456_k127_1542895_6	911008.GLAD_00155	1.641e-07	63.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	response regulator	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,Response_reg,SpoIIE
SRR25158456_k127_1542895_1	316067.Geob_2508	1.159e-91	311.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158456_k127_1542895_4	497964.CfE428DRAFT_1204	1.115e-31	139.0	COG2856@1|root,COG2856@2|Bacteria,46W5X@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1542895_3	378806.STAUR_7590	1.102e-32	137.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
SRR25158456_k127_1542895_2	378806.STAUR_7589	4.242e-34	140.0	COG1366@1|root,COG1366@2|Bacteria,1NJGJ@1224|Proteobacteria	1224|Proteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158456_k127_1542895_0	118005.AWNK01000003_gene2179	2.965e-256	802.0	COG0481@1|root,COG0481@2|Bacteria	2|Bacteria	M	GTPase activity	lepA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158456_k127_1542980_1	517418.Ctha_0774	3.163e-60	220.0	COG0635@1|root,COG0635@2|Bacteria,1FDQG@1090|Chlorobi	1090|Chlorobi	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158456_k127_1542980_2	316067.Geob_0705	3.115e-23	109.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1542980_3	204669.Acid345_0158	7.785e-18	95.0	COG1651@1|root,COG1651@2|Bacteria,3Y2G9@57723|Acidobacteria,2JIKS@204432|Acidobacteriia	204432|Acidobacteriia	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158456_k127_1542980_5	270374.MELB17_04152	9.772e-08	61.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,4680N@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0607 Rhodanese-related sulfurtransferase	yibN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158456_k127_1542980_0	1501230.ET33_16865	2.304e-66	239.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,26QWG@186822|Paenibacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158456_k127_1542980_6	391615.ABSJ01000038_gene412	0.0001525	47.0	2EGU9@1|root,33AKF@2|Bacteria,1NJPN@1224|Proteobacteria	1224|Proteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158456_k127_1542980_4	211165.AJLN01000104_gene6613	5.241e-12	76.0	COG3668@1|root,COG3668@2|Bacteria,1GKJ0@1117|Cyanobacteria,1JMAM@1189|Stigonemataceae	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158456_k127_1544338_1	215803.DB30_6944	1.075e-179	624.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2X2JP@28221|Deltaproteobacteria,2YY11@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
SRR25158456_k127_1544338_4	1380394.JADL01000003_gene4838	2.012e-23	115.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,2VEZQ@28211|Alphaproteobacteria,2JRJA@204441|Rhodospirillales	204441|Rhodospirillales	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
SRR25158456_k127_1544338_3	1123024.AUII01000025_gene2129	1.003e-50	192.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IH0Y@201174|Actinobacteria,4E30J@85010|Pseudonocardiales	201174|Actinobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1
SRR25158456_k127_1544338_5	204669.Acid345_4688	8.045e-14	80.0	COG1595@1|root,COG1595@2|Bacteria,3Y857@57723|Acidobacteria,2JN8U@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1544338_0	1267535.KB906767_gene3391	8.435e-199	639.0	COG0488@1|root,COG0488@2|Bacteria,3Y2H0@57723|Acidobacteria,2JI7S@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158456_k127_1544338_2	497964.CfE428DRAFT_2358	1.281e-150	488.0	COG0513@1|root,COG0513@2|Bacteria,46S5M@74201|Verrucomicrobia	74201|Verrucomicrobia	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158456_k127_1544338_6	1123248.KB893370_gene5153	6.113e-05	49.0	COG1359@1|root,COG1359@2|Bacteria,4P3Z8@976|Bacteroidetes	976|Bacteroidetes	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1545325_4	1121438.JNJA01000021_gene1378	8.769e-44	175.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2M7ZM@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158456_k127_1545325_1	1382359.JIAL01000001_gene1153	1.26e-120	401.0	COG0436@1|root,COG0436@2|Bacteria,3Y64P@57723|Acidobacteria,2JMB5@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_1545325_0	945713.IALB_1601	2.102e-189	606.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	sulP	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	iSbBS512_1146.SbBS512_E1370	STAS,Sulfate_transp
SRR25158456_k127_1545325_9	296587.XP_002499884.1	3.506e-07	60.0	COG3914@1|root,KOG4626@2759|Eukaryota,37IV9@33090|Viridiplantae,34GWN@3041|Chlorophyta	3041|Chlorophyta	GOT	O-linked N-acetylglucosamine transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_16,TPR_2,TPR_8
SRR25158456_k127_1545325_7	290397.Adeh_0015	6.346e-16	86.0	COG3266@1|root,COG3266@2|Bacteria,1N9VA@1224|Proteobacteria,42VXQ@68525|delta/epsilon subdivisions,2WSBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1545325_2	1238182.C882_0684	1.52e-102	356.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2JRMS@204441|Rhodospirillales	204441|Rhodospirillales	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158456_k127_1545325_5	589865.DaAHT2_0301	6.593e-42	164.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MJG9@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158456_k127_1545325_6	1343740.M271_13980	3.999e-26	118.0	COG1917@1|root,COG1917@2|Bacteria,2IKKG@201174|Actinobacteria	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
SRR25158456_k127_1545325_8	926566.Terro_0451	1.458e-09	68.0	COG2318@1|root,COG2318@2|Bacteria,3Y501@57723|Acidobacteria,2JJGU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_1545325_3	1237149.C900_05709	3.117e-65	233.0	COG0583@1|root,COG0583@2|Bacteria,4NGUF@976|Bacteroidetes,47N1G@768503|Cytophagia	976|Bacteroidetes	K	LysR substrate binding domain	-	-	-	ko:K03576	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158456_k127_1545754_2	1237149.C900_02707	4.735e-46	169.0	COG2050@1|root,COG2050@2|Bacteria,4NQ15@976|Bacteroidetes	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158456_k127_1545754_0	1380394.JADL01000003_gene5165	2.498e-238	748.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,2TQTE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	enoyl-CoA hydratase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158456_k127_1545754_1	1380394.JADL01000003_gene5164	6.952e-234	731.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
SRR25158456_k127_1547202_8	861299.J421_1228	4.586e-32	127.0	2E9H4@1|root,333Q5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1547202_11	331869.BAL199_03289	1.55e-27	115.0	COG3741@1|root,COG3741@2|Bacteria,1NBYI@1224|Proteobacteria	1224|Proteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1547202_6	1242864.D187_006336	1.932e-49	179.0	COG3682@1|root,COG3682@2|Bacteria,1RKDI@1224|Proteobacteria,4383A@68525|delta/epsilon subdivisions,2X3DA@28221|Deltaproteobacteria,2YVI8@29|Myxococcales	28221|Deltaproteobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158456_k127_1547202_2	215803.DB30_3367	3.818e-120	418.0	COG4219@1|root,COG4219@2|Bacteria,1PJ0I@1224|Proteobacteria,4380Y@68525|delta/epsilon subdivisions,2X3AY@28221|Deltaproteobacteria,2YV6Q@29|Myxococcales	28221|Deltaproteobacteria	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158456_k127_1547202_9	204669.Acid345_0209	1.336e-29	131.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria,2JKFK@204432|Acidobacteriia	204432|Acidobacteriia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158456_k127_1547202_0	661478.OP10G_4632	1.44e-184	605.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158456_k127_1547202_5	749927.AMED_4671	9.788e-51	194.0	COG2374@1|root,COG2374@2|Bacteria,2IIDP@201174|Actinobacteria,4EB5Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1547202_1	479432.Sros_6479	3.108e-153	510.0	COG2866@1|root,COG2866@2|Bacteria,2GN49@201174|Actinobacteria,4EHQM@85012|Streptosporangiales	201174|Actinobacteria	E	Zn_pept	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
SRR25158456_k127_1547202_7	591167.Sfla_2937	1.766e-33	149.0	COG1075@1|root,COG1075@2|Bacteria,2GN6J@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF676
SRR25158456_k127_1547202_3	56107.Cylst_1998	1.013e-68	252.0	28IG1@1|root,2Z8HJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1547202_12	395495.Lcho_4095	1.376e-21	112.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2WHQF@28216|Betaproteobacteria,1KM9W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_1547202_10	379066.GAU_0215	1.945e-28	126.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158456_k127_1547202_4	378806.STAUR_6820	2.118e-59	222.0	2CDDP@1|root,33XZD@2|Bacteria,1NVRR@1224|Proteobacteria,4380H@68525|delta/epsilon subdivisions,2X3AJ@28221|Deltaproteobacteria,2YV52@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1547202_13	378806.STAUR_6821	3.217e-06	55.0	COG3540@1|root,COG3540@2|Bacteria,1NWMQ@1224|Proteobacteria,4382N@68525|delta/epsilon subdivisions,2X3CQ@28221|Deltaproteobacteria,2YVFX@29|Myxococcales	28221|Deltaproteobacteria	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1547624_1	478741.JAFS01000001_gene1824	5.477e-69	250.0	COG0644@1|root,COG0644@2|Bacteria,46SNH@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158456_k127_1547624_3	1384054.N790_01640	2.805e-54	204.0	COG1595@1|root,COG1595@2|Bacteria,1RCMS@1224|Proteobacteria,1S55Z@1236|Gammaproteobacteria,1X59U@135614|Xanthomonadales	135614|Xanthomonadales	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1547624_0	1038922.PflQ2_1158	1.593e-234	745.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,1YP99@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158456_k127_1547624_2	1184267.A11Q_1101	6.562e-63	227.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2MT84@213481|Bdellovibrionales,2WRY5@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158456_k127_1548860_2	366649.XFF4834R_chr01190	8.454e-137	445.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria,1X3CR@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_1548860_14	1156935.QWE_16848	1.484e-27	115.0	2E8GZ@1|root,332V8@2|Bacteria,1NDF5@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_1	448385.sce0244	4.801e-197	646.0	COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales	28221|Deltaproteobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
SRR25158456_k127_1548860_13	1207055.C100_03715	1.332e-29	126.0	2BQVI@1|root,32JSD@2|Bacteria,1PS2A@1224|Proteobacteria,2V49D@28211|Alphaproteobacteria,2KADM@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
SRR25158456_k127_1548860_19	717606.PaecuDRAFT_1832	1.303e-15	85.0	COG2318@1|root,COG2318@2|Bacteria,1V8MI@1239|Firmicutes,4HJT7@91061|Bacilli,26XGY@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158456_k127_1548860_0	114615.BRADO1557	9.977e-204	654.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2TVBZ@28211|Alphaproteobacteria,3JXR2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_5	114615.BRADO1556	2.387e-90	317.0	COG2333@1|root,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria,2U6NT@28211|Alphaproteobacteria,3K1MG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_1548860_9	626418.bglu_2g01090	7.508e-69	257.0	COG3511@1|root,COG3540@1|root,COG3511@2|Bacteria,COG3540@2|Bacteria,1MWVP@1224|Proteobacteria,2VMZ4@28216|Betaproteobacteria,1K2NJ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM phosphoesterase	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158456_k127_1548860_10	187303.BN69_0831	2.786e-65	233.0	COG3161@1|root,COG3161@2|Bacteria,1RDSK@1224|Proteobacteria,2U80Y@28211|Alphaproteobacteria,3702X@31993|Methylocystaceae	28211|Alphaproteobacteria	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_11	196367.JNFG01000002_gene2264	2.047e-40	154.0	2E9D3@1|root,333KN@2|Bacteria,1N8RG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_20	1148.1673333	4.024e-11	64.0	2DP6Q@1|root,330SE@2|Bacteria,1G9Q4@1117|Cyanobacteria,1H610@1142|Synechocystis	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_6	246196.MSMEI_2454	1.377e-88	300.0	2DBMF@1|root,2Z9YG@2|Bacteria,2I871@201174|Actinobacteria,2377T@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_4	1192034.CAP_3732	1.921e-110	377.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,434NC@68525|delta/epsilon subdivisions,2WYZN@28221|Deltaproteobacteria,2Z10G@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158456_k127_1548860_8	1123073.KB899242_gene1649	5.614e-69	243.0	COG0500@1|root,COG0500@2|Bacteria,1QW0F@1224|Proteobacteria,1T3DH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158456_k127_1548860_12	502025.Hoch_4249	2.691e-40	158.0	COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,430Q2@68525|delta/epsilon subdivisions,2WW33@28221|Deltaproteobacteria,2YVXF@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
SRR25158456_k127_1548860_7	3067.XP_002956646.1	9.765e-70	257.0	COG0235@1|root,COG4229@1|root,KOG2630@2759|Eukaryota,KOG2631@2759|Eukaryota,37RJ7@33090|Viridiplantae,34JKW@3041|Chlorophyta	3041|Chlorophyta	E	Class II Aldolase and Adducin N-terminal domain	-	-	3.1.3.77,4.2.1.109	ko:K16054	ko00270,ko01100,map00270,map01100	M00034	R07392,R07395	RC01939,RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158456_k127_1548860_17	292459.STH2114	1.222e-20	106.0	COG4219@1|root,COG4219@2|Bacteria,1V7ER@1239|Firmicutes,24JSF@186801|Clostridia	186801|Clostridia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_16	1442599.JAAN01000030_gene2128	9.749e-24	116.0	2E9RD@1|root,333XM@2|Bacteria,1QUSZ@1224|Proteobacteria,1T2IE@1236|Gammaproteobacteria,1X7Q1@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1548860_3	204669.Acid345_1338	1.921e-134	434.0	COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria,2JHRI@204432|Acidobacteriia	204432|Acidobacteriia	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158456_k127_1548860_18	349161.Dred_3081	2.121e-20	101.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,2627P@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
SRR25158456_k127_1548860_15	1300345.LF41_981	1.464e-25	113.0	COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,1X8YU@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158456_k127_1549113_2	1265503.KB905164_gene1840	1.861e-16	84.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26,HTH_3
SRR25158456_k127_1549113_0	316067.Geob_1477	1.777e-19	104.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,42WPQ@68525|delta/epsilon subdivisions,2WV8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_1549113_1	47763.JNZA01000033_gene3073	2.553e-18	100.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria	201174|Actinobacteria	Q	amine oxidase	tynA	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid
SRR25158456_k127_1549539_2	378806.STAUR_3955	1.159e-75	257.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158456_k127_1549539_3	880073.Calab_0874	5.696e-42	177.0	COG0823@1|root,COG0823@2|Bacteria,2NQA4@2323|unclassified Bacteria	2|Bacteria	U	Periplasmic component of the Tol biopolymer transport system	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158456_k127_1549539_1	886293.Sinac_6796	1.627e-110	385.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158456_k127_1549539_0	1128427.KB904821_gene4050	8.811e-156	533.0	COG0457@1|root,COG3063@1|root,COG4995@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158456_k127_1551912_5	1131269.AQVV01000001_gene1298	1.438e-28	118.0	COG0249@1|root,COG0249@2|Bacteria	2|Bacteria	L	mismatched DNA binding	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SRR25158456_k127_1551912_6	1499967.BAYZ01000115_gene2918	1.334e-11	74.0	COG0745@1|root,COG0745@2|Bacteria	1499967.BAYZ01000115_gene2918|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1551912_3	399795.CtesDRAFT_PD4693	8.66e-38	146.0	COG4753@1|root,COG4753@2|Bacteria,1MZAI@1224|Proteobacteria,2WHQ8@28216|Betaproteobacteria,4AK2P@80864|Comamonadaceae	28216|Betaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1551912_4	1452536.JARE01000042_gene39	8.588e-35	139.0	COG4753@1|root,COG4753@2|Bacteria,2I2VC@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1551912_2	391625.PPSIR1_11570	2.725e-39	164.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
SRR25158456_k127_1551912_1	1396418.BATQ01000070_gene740	2.893e-49	192.0	COG1472@1|root,COG1472@2|Bacteria,46S5G@74201|Verrucomicrobia,2ITMC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158456_k127_1551912_0	71139.XP_010052092.1	5.128e-114	401.0	COG4886@1|root,2QTTB@2759|Eukaryota,37N6K@33090|Viridiplantae,3GFT3@35493|Streptophyta	35493|Streptophyta	T	Belongs to the protein kinase superfamily. Ser Thr protein kinase family	FLS2	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004675,GO:0004888,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0008150,GO:0008152,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010359,GO:0012505,GO:0016020,GO:0016043,GO:0016045,GO:0016192,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019199,GO:0019538,GO:0022898,GO:0023052,GO:0031410,GO:0031982,GO:0032409,GO:0032412,GO:0032879,GO:0033036,GO:0033037,GO:0033554,GO:0034762,GO:0034765,GO:0036211,GO:0038023,GO:0042545,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043269,GO:0043412,GO:0044070,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051234,GO:0051606,GO:0051641,GO:0051704,GO:0051707,GO:0051716,GO:0052386,GO:0052482,GO:0052542,GO:0052543,GO:0052544,GO:0052545,GO:0060089,GO:0065007,GO:0065009,GO:0070727,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097708,GO:0098542,GO:0098543,GO:0098581,GO:0098657,GO:0140096,GO:1901564,GO:1903959	2.7.11.1	ko:K13420	ko04016,ko04626,map04016,map04626	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	LRRNT_2,LRR_1,LRR_6,LRR_8,Pkinase,Pkinase_Tyr
SRR25158456_k127_1554884_0	215803.DB30_7238	2.005e-259	807.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YXZJ@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158456_k127_1561428_14	1192034.CAP_0384	3.34e-12	75.0	COG1716@1|root,COG1716@2|Bacteria,1PFN8@1224|Proteobacteria,435DQ@68525|delta/epsilon subdivisions,2WZR8@28221|Deltaproteobacteria,2Z2JZ@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158456_k127_1561428_12	113395.AXAI01000001_gene2852	3.984e-17	89.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_2,TPR_8,Trans_reg_C
SRR25158456_k127_1561428_5	1121920.AUAU01000014_gene2774	4.884e-43	181.0	COG0515@1|root,COG0515@2|Bacteria	1121920.AUAU01000014_gene2774|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1561428_10	1112212.JH584235_gene788	2.296e-20	107.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2K2KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158456_k127_1561428_7	886293.Sinac_4359	4.159e-26	117.0	COG1413@1|root,COG1413@2|Bacteria,2J42C@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158456_k127_1561428_9	1122604.JONR01000007_gene2934	2.239e-20	104.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,1MY07@1224|Proteobacteria	1224|Proteobacteria	O	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1561428_13	1237149.C900_01971	2.529e-13	80.0	COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1561428_8	639282.DEFDS_0877	6.827e-22	108.0	2CNNA@1|root,32SHE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1561428_4	639030.JHVA01000001_gene1782	2.443e-44	167.0	COG2318@1|root,COG2318@2|Bacteria,3Y5FN@57723|Acidobacteria,2JJTU@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158456_k127_1561428_11	1297742.A176_03230	1.962e-17	90.0	COG1011@1|root,COG1011@2|Bacteria,1Q2A2@1224|Proteobacteria,42WDV@68525|delta/epsilon subdivisions,2WRQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158456_k127_1561428_0	1382306.JNIM01000001_gene2570	3.875e-250	781.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158456_k127_1561428_2	439235.Dalk_2288	2.045e-71	278.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2MPW6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
SRR25158456_k127_1561428_3	1209989.TepiRe1_1418	3.536e-52	196.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,42G8Z@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158456_k127_1561428_6	1033737.CAEV01000110_gene1159	7.328e-41	158.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,36I5H@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158456_k127_1561428_16	479434.Sthe_3254	7.236e-08	65.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_1561428_1	452637.Oter_4614	1.454e-183	632.0	COG3590@1|root,COG3590@2|Bacteria,46UUX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Peptidase family M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158456_k127_1561428_15	32057.KB217478_gene3176	6.256e-12	69.0	COG3668@1|root,COG3668@2|Bacteria,1G7UC@1117|Cyanobacteria,1HSQF@1161|Nostocales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158456_k127_1561428_18	472759.Nhal_1992	4.683e-05	51.0	2EA6P@1|root,33A4Y@2|Bacteria,1NK01@1224|Proteobacteria,1SIDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158456_k127_1561789_2	28072.Nos7524_4685	3.839e-21	93.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_1561789_0	179408.Osc7112_2266	5.355e-35	157.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1G3Z1@1117|Cyanobacteria,1HEI8@1150|Oscillatoriales	1117|Cyanobacteria	KT	Diguanylate cyclase with PAS PAC and GAF sensors	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
SRR25158456_k127_1561789_3	234267.Acid_3898	5.053e-10	74.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158456_k127_1561789_1	234267.Acid_6752	3.236e-22	114.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158456_k127_1561947_4	404589.Anae109_0486	6.711e-13	83.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transglycosylase	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
SRR25158456_k127_1561947_0	398767.Glov_1909	1.109e-207	671.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158456_k127_1561947_3	1499967.BAYZ01000091_gene3428	2.919e-31	139.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
SRR25158456_k127_1561947_2	714943.Mucpa_2739	3.09e-57	218.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes,1IS0X@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	vanX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
SRR25158456_k127_1561947_1	443255.SCLAV_p0535	3.728e-70	246.0	2F3XQ@1|root,33WPT@2|Bacteria	2|Bacteria	S	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158456_k127_1568880_5	47763.JNZA01000004_gene3867	3.146e-68	245.0	COG3591@1|root,COG3591@2|Bacteria,2IBUN@201174|Actinobacteria	201174|Actinobacteria	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158456_k127_1568880_8	1123504.JQKD01000036_gene3126	4.42e-43	177.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,4ACFV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
SRR25158456_k127_1568880_4	204669.Acid345_3314	6.245e-88	304.0	COG0578@1|root,COG0578@2|Bacteria,3Y2YF@57723|Acidobacteria,2JI40@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158456_k127_1568880_2	1121918.ARWE01000001_gene3122	1.51e-105	359.0	COG1752@1|root,COG1752@2|Bacteria,1Q4S1@1224|Proteobacteria,42S86@68525|delta/epsilon subdivisions,2WNJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158456_k127_1568880_7	189753.AXAS01000084_gene6056	1.184e-44	184.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,Guanylate_cyc,SAM_1,Trans_reg_C
SRR25158456_k127_1568880_11	1442599.JAAN01000041_gene3106	1.076e-15	91.0	COG0745@1|root,COG0745@2|Bacteria	1442599.JAAN01000041_gene3106|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1568880_15	111780.Sta7437_4426	3.049e-05	54.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1G0VR@1117|Cyanobacteria,3VHRJ@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SRR25158456_k127_1568880_14	1397528.Q671_11215	1.458e-12	71.0	2DRAI@1|root,33AYP@2|Bacteria,1NJXU@1224|Proteobacteria,1SHXT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1568880_13	1122947.FR7_0535	3.203e-13	74.0	COG3668@1|root,COG3668@2|Bacteria,1VHZU@1239|Firmicutes	1239|Firmicutes	S	PFAM plasmid	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158456_k127_1568880_9	1267535.KB906767_gene237	2.096e-37	161.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_1568880_0	1300345.LF41_1045	2.554e-221	695.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQRJ@1236|Gammaproteobacteria,1X83S@135614|Xanthomonadales	135614|Xanthomonadales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158456_k127_1568880_3	1380391.JIAS01000013_gene3651	1.954e-94	326.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,2TQZZ@28211|Alphaproteobacteria,2JPG0@204441|Rhodospirillales	204441|Rhodospirillales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158456_k127_1568880_6	1510531.JQJJ01000009_gene1204	8.412e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,2TWX8@28211|Alphaproteobacteria,3K3W3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158456_k127_1568880_12	861299.J421_0665	3.089e-14	82.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
SRR25158456_k127_1568880_1	861299.J421_0666	2.131e-166	531.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1568880_10	388051.AUFE01000045_gene2357	1.171e-26	119.0	COG0454@1|root,COG0456@2|Bacteria,1QU9D@1224|Proteobacteria,2VUVY@28216|Betaproteobacteria,1KIF4@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158456_k127_1576095_1	378806.STAUR_0942	2.045e-90	306.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158456_k127_1576095_2	1033802.SSPSH_001573	1.058e-87	303.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
SRR25158456_k127_1576095_3	1405.DJ92_341	4.025e-09	60.0	COG3813@1|root,COG3813@2|Bacteria,1W43V@1239|Firmicutes,4HZG5@91061|Bacilli,1ZP8A@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
SRR25158456_k127_1576095_4	1142394.PSMK_p00270	2.211e-05	56.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
SRR25158456_k127_1576095_0	398767.Glov_3079	3.139e-99	329.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SRR25158456_k127_1580204_0	1035191.HMPREF0185_00592	6.446e-110	372.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2U25U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
SRR25158456_k127_1580204_2	1198114.AciX9_0530	1.778e-49	189.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
SRR25158456_k127_1580204_1	1142394.PSMK_08370	1.558e-87	302.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158456_k127_1587779_1	635013.TherJR_0997	5.752e-159	523.0	COG0395@1|root,COG5001@1|root,COG5002@1|root,COG0395@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9
SRR25158456_k127_1587779_9	1384056.N787_01780	1.448e-29	124.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1587779_10	1123276.KB893260_gene2577	6.444e-17	85.0	2AP2K@1|root,31E40@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1587779_0	1519464.HY22_12110	8.236e-254	852.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
SRR25158456_k127_1587779_2	1047013.AQSP01000123_gene1546	2.058e-135	463.0	COG4953@1|root,COG4953@2|Bacteria,2NQMA@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
SRR25158456_k127_1587779_6	196367.JNFG01000204_gene426	9.646e-70	251.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,2VHTI@28216|Betaproteobacteria,1K5IK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
SRR25158456_k127_1587779_8	749414.SBI_03806	1.99e-30	129.0	2CAZG@1|root,2ZBT6@2|Bacteria,2GW3H@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
SRR25158456_k127_1587779_3	365046.Rta_16960	1.954e-93	322.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158456_k127_1587779_4	1121943.KB899992_gene2159	1.635e-78	274.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158456_k127_1587779_5	1121943.KB899992_gene2160	5.304e-76	265.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
SRR25158456_k127_1587779_7	426117.M446_1666	9.158e-46	177.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2TVMG@28211|Alphaproteobacteria,1JRRE@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Zinc ribbon NADH pyrophosphatase	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
SRR25158456_k127_1590037_1	1123274.KB899421_gene1747	3.255e-65	229.0	COG0809@1|root,COG0809@2|Bacteria,2J5HY@203691|Spirochaetes	203691|Spirochaetes	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158456_k127_1590037_0	69395.JQLZ01000003_gene483	0.0	1517.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2KG4I@204458|Caulobacterales	204458|Caulobacterales	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
SRR25158456_k127_1598577_1	68170.KL590510_gene7215	4.3e-50	180.0	COG3647@1|root,COG3647@2|Bacteria,2IATE@201174|Actinobacteria,4E3YF@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SRR25158456_k127_1598577_2	518766.Rmar_2320	1.503e-17	93.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158456_k127_1598577_0	682795.AciX8_0140	1.145e-84	290.0	COG4941@1|root,COG4941@2|Bacteria,3Y38B@57723|Acidobacteria,2JP46@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1599219_8	1089553.Tph_c08810	2.542e-20	101.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,42FV2@68295|Thermoanaerobacterales	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR25158456_k127_1599219_1	1123371.ATXH01000004_gene1740	2.186e-145	470.0	COG0162@1|root,COG0162@2|Bacteria,2GGUK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158456_k127_1599219_3	357808.RoseRS_4428	1.752e-126	417.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158456_k127_1599219_6	1121422.AUMW01000008_gene477	1.793e-51	194.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,261FX@186807|Peptococcaceae	186801|Clostridia	S	PFAM Rhomboid family protein	GlpG	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158456_k127_1599219_2	401526.TcarDRAFT_2658	4.476e-127	426.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H1YA@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158456_k127_1599219_7	765912.Thimo_0978	5.515e-33	134.0	COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,1SADN@1236|Gammaproteobacteria,1WZ4E@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158456_k127_1599219_0	243231.GSU0626	6.408e-168	535.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,43T4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158456_k127_1599219_4	882.DVU_0090	4.5e-120	410.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria,2M7SU@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158456_k127_1599219_9	1121272.KB903249_gene2169	1.431e-15	91.0	COG2373@1|root,COG2374@1|root,COG3250@1|root,COG5492@1|root,COG2373@2|Bacteria,COG2374@2|Bacteria,COG3250@2|Bacteria,COG5492@2|Bacteria,2I2E0@201174|Actinobacteria,4DF33@85008|Micromonosporales	201174|Actinobacteria	E	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
SRR25158456_k127_1599219_5	32057.KB217478_gene497	1.39e-61	239.0	COG1404@1|root,COG1404@2|Bacteria,1G7AR@1117|Cyanobacteria,1HIWC@1161|Nostocales	1117|Cyanobacteria	O	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
SRR25158456_k127_1603698_0	204669.Acid345_2911	4.567e-154	499.0	COG2304@1|root,COG2304@2|Bacteria,3Y6GT@57723|Acidobacteria,2JKSI@204432|Acidobacteriia	204432|Acidobacteriia	S	TROVE domain	-	-	-	-	-	-	-	-	-	-	-	-	TROVE
SRR25158456_k127_1603698_2	1121015.N789_03360	1.089e-05	55.0	COG0515@1|root,COG0515@2|Bacteria,1QXK0@1224|Proteobacteria,1T3DE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	Pkinase,TIR_2
SRR25158456_k127_1649207_0	861299.J421_2451	4.03e-146	480.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158456_k127_1649207_3	1121468.AUBR01000016_gene2351	7.781e-37	147.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,42GU3@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Lytic transglycosylase catalytic	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158456_k127_1649207_2	671143.DAMO_0325	1.111e-74	260.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
SRR25158456_k127_1649207_1	215803.DB30_0258	1.17e-103	349.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YWSA@29|Myxococcales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158456_k127_1660444_13	103690.17134448	1.329e-17	87.0	COG0642@1|root,COG0745@1|root,COG4252@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG4252@2|Bacteria,1G3JA@1117|Cyanobacteria,1HJCM@1161|Nostocales	1117|Cyanobacteria	T	Integral membrane sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA,Response_reg
SRR25158456_k127_1660444_7	497964.CfE428DRAFT_0931	1.457e-45	179.0	COG2230@1|root,COG2230@2|Bacteria,46Z8K@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1660444_1	1429851.X548_15495	3.702e-62	234.0	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,1S5G3@1236|Gammaproteobacteria,1XC69@135614|Xanthomonadales	135614|Xanthomonadales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158456_k127_1660444_6	1403819.BATR01000137_gene4837	7.789e-46	186.0	COG1560@1|root,COG1560@2|Bacteria,46XF4@74201|Verrucomicrobia,2IVQY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
SRR25158456_k127_1660444_5	1380347.JNII01000007_gene386	3.162e-47	184.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ERZZ@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRR25158456_k127_1660444_4	479431.Namu_4203	1.207e-47	190.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ERZZ@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRR25158456_k127_1660444_2	1131814.JAFO01000001_gene1847	2.693e-61	235.0	COG1216@1|root,COG2120@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2120@2|Bacteria,COG2227@2|Bacteria,1PHP0@1224|Proteobacteria,2VDUQ@28211|Alphaproteobacteria,3F23E@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158456_k127_1660444_9	479434.Sthe_3170	6.937e-40	162.0	COG0457@1|root,COG0515@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	200795|Chloroflexi	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158456_k127_1660444_3	562743.JH976434_gene1067	6.024e-51	189.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158456_k127_1660444_11	682795.AciX8_2392	3.13e-22	99.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria,2JJVA@204432|Acidobacteriia	204432|Acidobacteriia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158456_k127_1660444_0	204669.Acid345_0153	9.18e-172	554.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria,2JKRD@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158456_k127_1660444_12	378806.STAUR_1679	1.107e-17	98.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2YVN7@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158456_k127_1660444_10	204669.Acid345_2716	5.432e-26	126.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_1660444_8	309807.SRU_2793	2.215e-42	168.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1FJAI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158456_k127_1663952_2	880073.Calab_0163	2.206e-135	440.0	COG1220@1|root,COG1220@2|Bacteria,2NP00@2323|unclassified Bacteria	2|Bacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158456_k127_1663952_11	1283300.ATXB01000001_gene2139	1.645e-15	78.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1663952_5	1267534.KB906755_gene4489	1.632e-83	302.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158456_k127_1663952_4	661478.OP10G_2908	4.246e-104	356.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ybhF-C	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158456_k127_1663952_9	266779.Meso_0129	2.409e-39	159.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2TTRG@28211|Alphaproteobacteria,43M63@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_1663952_13	1280390.CBQR020000149_gene3855	1.958e-09	68.0	COG1309@1|root,COG1309@2|Bacteria,1VIDE@1239|Firmicutes,4HQMD@91061|Bacilli,26ZZY@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158456_k127_1663952_0	1340493.JNIF01000003_gene1675	7.573e-245	788.0	COG1629@1|root,COG4771@2|Bacteria,3Y2HF@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158456_k127_1663952_1	118168.MC7420_6877	9.145e-182	580.0	COG1012@1|root,COG1012@2|Bacteria,1G046@1117|Cyanobacteria,1H7Q6@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Aldehyde dehydrogenase	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.gabD,iJN678.gabD	Aldedh
SRR25158456_k127_1663952_8	105559.Nwat_1040	1.043e-50	188.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,1X1P9@135613|Chromatiales	135613|Chromatiales	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
SRR25158456_k127_1663952_6	234267.Acid_5756	3.73e-80	284.0	COG0515@1|root,COG0515@2|Bacteria,3Y3NW@57723|Acidobacteria	57723|Acidobacteria	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158456_k127_1663952_7	1254432.SCE1572_21210	4.524e-61	218.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1663952_3	1437425.CSEC_0969	4.675e-107	356.0	COG0306@1|root,COG0306@2|Bacteria,2JH20@204428|Chlamydiae	204428|Chlamydiae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158456_k127_1665811_12	1192034.CAP_3143	2.926e-29	133.0	COG4258@1|root,COG4258@2|Bacteria,1QX46@1224|Proteobacteria,42QK9@68525|delta/epsilon subdivisions,2WKGH@28221|Deltaproteobacteria,2YUF0@29|Myxococcales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158456_k127_1665811_9	671143.DAMO_0360	6.378e-38	162.0	COG1373@1|root,COG1373@2|Bacteria,2NQNV@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158456_k127_1665811_2	640081.Dsui_3298	3.156e-238	785.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,2VHSM@28216|Betaproteobacteria,2KVUD@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158456_k127_1665811_0	1173022.Cri9333_2944	0.0	1217.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_1665811_3	522306.CAP2UW1_4073	5.565e-186	615.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VZID@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
SRR25158456_k127_1665811_8	1380347.JNII01000008_gene4221	4.016e-38	164.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria,4ESKP@85013|Frankiales	201174|Actinobacteria	O	Sucrase/ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
SRR25158456_k127_1665811_6	446462.Amir_5269	1.106e-80	283.0	COG2850@1|root,COG2850@2|Bacteria,2GMR2@201174|Actinobacteria,4DYRP@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158456_k127_1665811_4	215803.DB30_1115	5.522e-136	445.0	COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,42QJM@68525|delta/epsilon subdivisions,2WXDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
SRR25158456_k127_1665811_5	525897.Dbac_3330	4.964e-107	371.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,42MA1@68525|delta/epsilon subdivisions,2WMVY@28221|Deltaproteobacteria,2MGKV@213115|Desulfovibrionales	28221|Deltaproteobacteria	EJ	Asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158456_k127_1665811_1	861299.J421_1502	0.0	1212.0	COG4447@1|root,COG4447@2|Bacteria,1ZUS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_1665811_16	2325.TKV_c24610	1.979e-20	96.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,42GUD@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158456_k127_1665811_13	1267533.KB906734_gene4260	6.723e-26	109.0	COG0238@1|root,COG0238@2|Bacteria,3Y53K@57723|Acidobacteria,2JN1Z@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S18	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158456_k127_1665811_17	338963.Pcar_1997	0.0003818	52.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,43SRH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
SRR25158456_k127_1665811_10	638303.Thal_0175	5.426e-37	146.0	COG0359@1|root,COG0359@2|Bacteria,2G44E@200783|Aquificae	200783|Aquificae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158456_k127_1665811_11	765913.ThidrDRAFT_4323	4.007e-33	145.0	COG2230@1|root,COG4976@1|root,COG2230@2|Bacteria,COG4976@2|Bacteria,1QZMW@1224|Proteobacteria	1224|Proteobacteria	M	Methionine biosynthesis protein MetW	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Methyltransf_23
SRR25158456_k127_1665811_14	1460640.JCM19046_4023	1.191e-24	114.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus	91061|Bacilli	O	membrane protein (homolog of Drosophila rhomboid)	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
SRR25158456_k127_1665811_7	1120973.AQXL01000128_gene2783	7.938e-46	175.0	COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,279ZC@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158456_k127_1665811_15	868131.MSWAN_2422	1.914e-21	96.0	COG0115@1|root,arCOG02297@2157|Archaea,2XT9V@28890|Euryarchaeota,23NNK@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158456_k127_1669668_3	903818.KI912268_gene2060	2.662e-80	284.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
SRR25158456_k127_1669668_2	861299.J421_0738	1.1e-90	319.0	COG1228@1|root,COG1228@2|Bacteria,1ZTC8@142182|Gemmatimonadetes	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158456_k127_1669668_0	1267535.KB906767_gene322	2.763e-132	458.0	COG1228@1|root,COG1228@2|Bacteria,3Y6Y2@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158456_k127_1669668_1	861299.J421_0736	7.395e-113	379.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158456_k127_1669668_4	1177154.Y5S_02844	1.858e-06	54.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,1RNHR@1236|Gammaproteobacteria,1XIAT@135619|Oceanospirillales	135619|Oceanospirillales	P	receptor	-	-	-	ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_1672532_0	1173027.Mic7113_3921	1e-110	400.0	COG0515@1|root,COG0642@1|root,COG0745@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,PAS_4,Pkinase,Response_reg
SRR25158456_k127_1672532_1	864702.OsccyDRAFT_4730	2.165e-41	178.0	COG4251@1|root,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1H9CH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_1682399_2	768670.Calni_1156	1.312e-138	457.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzx	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158456_k127_1682399_18	797299.HALLA_13365	8.405e-23	108.0	COG0500@1|root,arCOG01402@2157|Archaea,2XYWP@28890|Euryarchaeota,23WPJ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158456_k127_1682399_14	1173026.Glo7428_3729	2.538e-55	216.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K13683	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158456_k127_1682399_16	118168.MC7420_7338	2.602e-45	176.0	2DTTJ@1|root,32UVW@2|Bacteria,1G8TS@1117|Cyanobacteria,1HCTF@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158456_k127_1682399_9	69279.BG36_08280	1.966e-96	329.0	COG0438@1|root,COG0438@2|Bacteria,1MUIZ@1224|Proteobacteria,2U6K7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158456_k127_1682399_12	1121403.AUCV01000031_gene2829	2.104e-79	291.0	COG1091@1|root,COG1091@2|Bacteria,1Q48H@1224|Proteobacteria,42YKE@68525|delta/epsilon subdivisions,2WTPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158456_k127_1682399_4	314278.NB231_16878	2.948e-135	444.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WXX0@135613|Chromatiales	135613|Chromatiales	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
SRR25158456_k127_1682399_5	1009370.ALO_00650	7.32e-134	453.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4H3QB@909932|Negativicutes	909932|Negativicutes	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158456_k127_1682399_10	582899.Hden_0188	3.876e-96	334.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,2TSZW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
SRR25158456_k127_1682399_11	56780.SYN_02668	1.278e-86	299.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42PPG@68525|delta/epsilon subdivisions,2WJGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158456_k127_1682399_17	321846.PS417_08185	1.617e-41	165.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)	wbpL	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158456_k127_1682399_1	1123368.AUIS01000017_gene2585	4.176e-152	486.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,2NC8B@225057|Acidithiobacillales	225057|Acidithiobacillales	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158456_k127_1682399_0	886293.Sinac_4068	5.202e-165	535.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2IX1D@203682|Planctomycetes	203682|Planctomycetes	H	May be the GTPase, regulating ATP sulfurylase activity	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158456_k127_1682399_3	1129374.AJE_16259	2.399e-135	446.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,464C9@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes	cysD	GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0044237,GO:0050896,GO:0070566	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	iUMNK88_1353.UMNK88_3428,iYL1228.KPN_03114	PAPS_reduct
SRR25158456_k127_1682399_13	246194.CHY_2693	2.322e-67	237.0	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,24GDY@186801|Clostridia,42GWA@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158456_k127_1682399_19	443254.Marpi_0188	0.0001651	54.0	COG3307@1|root,COG3307@2|Bacteria,2GCHD@200918|Thermotogae	200918|Thermotogae	M	PFAM O-Antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158456_k127_1682399_6	886293.Sinac_3895	3.217e-131	443.0	COG1086@1|root,COG1086@2|Bacteria,2IWVA@203682|Planctomycetes	203682|Planctomycetes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158456_k127_1682399_8	671143.DAMO_0940	3.755e-97	322.0	COG0279@1|root,COG0279@2|Bacteria,2NQPQ@2323|unclassified Bacteria	2|Bacteria	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158456_k127_1682399_15	1408164.MOLA814_00703	2.211e-51	199.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2WEA7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
SRR25158456_k127_1682399_7	1408164.MOLA814_00702	3.328e-103	351.0	COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria	1224|Proteobacteria	H	Transaldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158456_k127_1742933_3	926566.Terro_4318	4.058e-07	61.0	COG1028@1|root,COG1028@2|Bacteria,3Y3CD@57723|Acidobacteria,2JHIF@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158456_k127_1742933_2	1267534.KB906754_gene3005	1.585e-66	243.0	COG2186@1|root,COG2186@2|Bacteria,3Y47U@57723|Acidobacteria,2JI8P@204432|Acidobacteriia	204432|Acidobacteriia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158456_k127_1742933_0	760192.Halhy_4379	1.699e-128	458.0	COG3507@1|root,COG3507@2|Bacteria,4NHZW@976|Bacteroidetes,1IR40@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	arbA_2	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
SRR25158456_k127_1742933_1	1124780.ANNU01000008_gene2677	4.097e-128	457.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes,47MS0@768503|Cytophagia	976|Bacteroidetes	V	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
SRR25158456_k127_1746870_1	443143.GM18_3609	2.461e-53	191.0	COG3267@1|root,COG3267@2|Bacteria,1REY9@1224|Proteobacteria,42RJB@68525|delta/epsilon subdivisions,2WN99@28221|Deltaproteobacteria,43TEB@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR25158456_k127_1746870_0	316067.Geob_2159	8.227e-168	550.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SRR25158456_k127_1746870_3	1278073.MYSTI_05217	6.378e-36	141.0	COG0745@1|root,COG0745@2|Bacteria,1N1TA@1224|Proteobacteria,42V03@68525|delta/epsilon subdivisions,2WPZR@28221|Deltaproteobacteria,2YVV2@29|Myxococcales	28221|Deltaproteobacteria	T	Chemotaxis protein CheY	cheY40H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SRR25158456_k127_1746870_4	1232410.KI421413_gene817	6.94e-35	153.0	COG0745@1|root,COG0745@2|Bacteria,1N9YT@1224|Proteobacteria,42W15@68525|delta/epsilon subdivisions,2WS2V@28221|Deltaproteobacteria,43T56@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	regulator, PATAN and FRGAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
SRR25158456_k127_1746870_5	1123371.ATXH01000011_gene65	3.251e-28	124.0	COG0781@1|root,COG0781@2|Bacteria,2GHUU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158456_k127_1746870_2	224324.aq_132	1.013e-47	175.0	COG0054@1|root,COG0054@2|Bacteria,2G3YV@200783|Aquificae	200783|Aquificae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158456_k127_1746870_6	1144275.COCOR_07749	0.0003341	44.0	COG5285@1|root,COG5285@2|Bacteria,1R9W1@1224|Proteobacteria	1224|Proteobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158456_k127_1752018_5	1234364.AMSF01000005_gene720	4.824e-18	86.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1N8ZK@1224|Proteobacteria,1T6Z9@1236|Gammaproteobacteria,1X8G8@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158456_k127_1752018_3	1144275.COCOR_01763	4.927e-151	494.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,437YB@68525|delta/epsilon subdivisions,2X387@28221|Deltaproteobacteria,2YVXR@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_1752018_1	861299.J421_4258	1.898e-176	563.0	COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158456_k127_1752018_2	977880.RALTA_B1342	2.677e-152	524.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_1752018_4	446468.Ndas_0636	5.729e-44	171.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria,4EKNJ@85012|Streptosporangiales	201174|Actinobacteria	Q	N-acetyltransferase	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR25158456_k127_1752018_0	1385517.N800_11920	3.612e-292	910.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,1X4B6@135614|Xanthomonadales	135614|Xanthomonadales	O	peptidase	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158456_k127_1770224_0	1242864.D187_007714	8.716e-163	526.0	COG0714@1|root,COG0714@2|Bacteria,1NSN5@1224|Proteobacteria,437FG@68525|delta/epsilon subdivisions,2X2N3@28221|Deltaproteobacteria,2YTXE@29|Myxococcales	28221|Deltaproteobacteria	D	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,DUF3686
SRR25158456_k127_1770224_3	1380394.JADL01000004_gene6087	8.297e-34	140.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2U5JV@28211|Alphaproteobacteria,2JSDB@204441|Rhodospirillales	204441|Rhodospirillales	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRR25158456_k127_1770224_4	1385517.N800_13895	5.262e-11	72.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG2203@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1XDBG@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
SRR25158456_k127_1770224_2	272134.KB731324_gene3403	3.34e-39	165.0	COG0705@1|root,COG0705@2|Bacteria,1G5DT@1117|Cyanobacteria,1H961@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158456_k127_1770224_1	502025.Hoch_0805	5.036e-45	183.0	COG4076@1|root,COG4076@2|Bacteria,1Q5QG@1224|Proteobacteria,43A7U@68525|delta/epsilon subdivisions,2X218@28221|Deltaproteobacteria,2Z25F@29|Myxococcales	28221|Deltaproteobacteria	S	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PrmA
SRR25158456_k127_1775404_2	379066.GAU_0843	7.809e-140	461.0	COG0577@1|root,COG0577@2|Bacteria,1ZSUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_1775404_7	379066.GAU_0844	3.37e-94	335.0	COG1136@1|root,COG1136@2|Bacteria,1ZUSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_1775404_5	379066.GAU_0845	8.464e-110	370.0	COG0845@1|root,COG0845@2|Bacteria,1ZU07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158456_k127_1775404_19	573.JG24_09335	7.262e-05	55.0	COG3678@1|root,COG3678@2|Bacteria,1RBDH@1224|Proteobacteria,1S2DT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NPTU	P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein	spy	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507	-	ko:K06006	-	-	-	-	ko00000,ko03110	-	-	-	LTXXQ
SRR25158456_k127_1775404_18	880073.Calab_1787	3.987e-08	63.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,OmpA,TPR_16,fn3
SRR25158456_k127_1775404_6	502025.Hoch_5854	2.761e-95	355.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla28	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_1775404_12	290397.Adeh_3532	3.928e-29	135.0	COG0642@1|root,COG2205@2|Bacteria,1QX8G@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
SRR25158456_k127_1775404_16	1223521.BBJX01000001_gene917	4.109e-14	86.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
SRR25158456_k127_1775404_0	1340493.JNIF01000004_gene652	1.669e-241	761.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_1775404_11	1173024.KI912149_gene5707	4.214e-30	126.0	COG4113@1|root,COG4113@2|Bacteria,1GDRC@1117|Cyanobacteria,1JMJ1@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1775404_17	870187.Thini_2230	7.493e-10	62.0	2DSE5@1|root,33FS0@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
SRR25158456_k127_1775404_1	1123073.KB899242_gene1567	4.626e-156	506.0	2DBJC@1|root,2Z9K5@2|Bacteria,1NQYW@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 47	-	-	3.2.1.113	ko:K01230	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00073,M00074	R05982,R06722	-	ko00000,ko00001,ko00002,ko01000,ko04131	-	GH47	-	Glyco_hydro_47
SRR25158456_k127_1775404_10	1502724.FF80_03445	1.107e-30	127.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2UCXT@28211|Alphaproteobacteria,3N8UB@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158456_k127_1775404_4	1459636.NTE_00447	4.763e-114	379.0	COG3832@1|root,arCOG05261@2157|Archaea	2157|Archaea	H	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_1775404_9	1267534.KB906754_gene2722	2.265e-49	178.0	COG0640@1|root,COG0640@2|Bacteria,3Y4SS@57723|Acidobacteria,2JN6X@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158456_k127_1775404_3	929712.KI912613_gene4204	7.385e-130	427.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_1775404_15	1121904.ARBP01000005_gene4801	1.465e-18	97.0	2APV8@1|root,31EZQ@2|Bacteria,4P91U@976|Bacteroidetes,47WG9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1775404_20	1120936.KB907208_gene567	0.0001517	53.0	2FDZQ@1|root,345ZY@2|Bacteria,2H799@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1775404_8	134676.ACPL_3231	1.439e-92	322.0	COG0438@1|root,COG0438@2|Bacteria,2GMR9@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_1775404_13	1121904.ARBP01000005_gene4634	3.944e-24	113.0	2EBPK@1|root,335PP@2|Bacteria,4NWAZ@976|Bacteroidetes,47W5A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1775404_14	929712.KI912613_gene4200	2.958e-22	108.0	2DC71@1|root,32TZ3@2|Bacteria,2H338@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1779598_1	234267.Acid_5032	1.212e-64	229.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_5032|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1779598_2	234267.Acid_5033	3.127e-59	228.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,3Y3AX@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158456_k127_1779598_0	903818.KI912268_gene1426	2e-94	316.0	COG1385@1|root,COG1385@2|Bacteria	2|Bacteria	J	rRNA (uridine-N3-)-methyltransferase activity	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158456_k127_1779598_4	1123399.AQVE01000003_gene2201	1.754e-24	111.0	COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SRR25158456_k127_1779598_3	1519464.HY22_13745	1.192e-53	205.0	COG0618@1|root,COG0618@2|Bacteria,1FEID@1090|Chlorobi	1090|Chlorobi	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1780957_3	1268072.PSAB_08715	3.97e-14	75.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,4HIFP@91061|Bacilli,26TIF@186822|Paenibacillaceae	91061|Bacilli	M	lytic transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158456_k127_1780957_0	401053.AciPR4_3379	1.895e-124	411.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_1780957_1	1191523.MROS_1703	6.221e-63	225.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158456_k127_1780957_2	518766.Rmar_0669	2.903e-41	171.0	COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1FJ16@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacillithiol biosynthesis BshC	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
SRR25158456_k127_1780957_4	880073.Calab_3787	0.000392	44.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	yccK	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31,TehB
SRR25158456_k127_1788601_0	713587.THITH_08235	2.29e-188	627.0	COG2319@1|root,COG5635@1|root,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,1T4BE@1236|Gammaproteobacteria,1WW20@135613|Chromatiales	135613|Chromatiales	T	WD40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DUF4062,WD40
SRR25158456_k127_1788601_4	290317.Cpha266_0840	5.039e-19	95.0	COG1357@1|root,COG1672@1|root,COG2319@1|root,COG5635@1|root,COG1357@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1FF2B@1090|Chlorobi	1090|Chlorobi	T	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,WD40
SRR25158456_k127_1788601_5	1131462.DCF50_p1962	2.749e-09	66.0	2DNAV@1|root,32WHG@2|Bacteria,1VC5B@1239|Firmicutes,2536E@186801|Clostridia	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158456_k127_1788601_3	379066.GAU_3293	4.107e-33	133.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
SRR25158456_k127_1788601_1	1009370.ALO_01789	6.777e-128	432.0	COG1814@1|root,COG1814@2|Bacteria,1UQWP@1239|Firmicutes,4H8S9@909932|Negativicutes	909932|Negativicutes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158456_k127_1788601_2	66692.ABC0375	4.394e-57	206.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,4HB28@91061|Bacilli,1ZC3P@1386|Bacillus	91061|Bacilli	IQ	Class II Aldolase and Adducin N-terminal domain	yuxG	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158456_k127_1798902_0	861299.J421_0281	8.111e-48	183.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_1798902_4	1449346.JQMO01000003_gene4617	2.339e-13	83.0	COG0699@1|root,COG0699@2|Bacteria,2I8FM@201174|Actinobacteria,2M4QE@2063|Kitasatospora	201174|Actinobacteria	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1798902_1	69395.JQLZ01000003_gene103	1.195e-22	115.0	2DC46@1|root,2ZCU7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1798902_2	267608.RSc3027	8.561e-17	83.0	COG4676@1|root,COG4676@2|Bacteria,1R801@1224|Proteobacteria,2VPGN@28216|Betaproteobacteria,1K4IF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2135
SRR25158456_k127_1800288_5	1184267.A11Q_1050	4.017e-35	152.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2MTW3@213481|Bdellovibrionales,2WKTX@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR25158456_k127_1800288_3	477974.Daud_0268	2.695e-78	281.0	COG0438@1|root,COG2105@1|root,COG0438@2|Bacteria,COG2105@2|Bacteria,1UVR9@1239|Firmicutes,25KKW@186801|Clostridia,265WT@186807|Peptococcaceae	186801|Clostridia	M	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRR25158456_k127_1800288_6	398767.Glov_1520	3.259e-32	133.0	COG2519@1|root,COG3119@1|root,COG2519@2|Bacteria,COG3119@2|Bacteria,1NIZU@1224|Proteobacteria,42Z5U@68525|delta/epsilon subdivisions,2WU2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158456_k127_1800288_4	1131269.AQVV01000012_gene2577	1.321e-41	167.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158456_k127_1800288_7	1254432.SCE1572_42555	6.793e-26	123.0	COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria	1224|Proteobacteria	S	Sulfopyruvate decarboxylase	comD	-	4.1.1.79,4.1.1.82	ko:K06034,ko:K09459	ko00440,ko00680,ko01100,ko01120,ko01130,map00440,map00680,map01100,map01120,map01130	M00358	R04053,R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158456_k127_1800288_1	1463920.JOGB01000005_gene1957	1.09e-92	316.0	COG1213@1|root,COG2513@1|root,COG1213@2|Bacteria,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	-	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
SRR25158456_k127_1800288_2	679201.HMPREF9334_01512	1.702e-87	297.0	COG2877@1|root,COG2877@2|Bacteria,1TR2G@1239|Firmicutes,4H20D@909932|Negativicutes	909932|Negativicutes	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158456_k127_1800288_8	1303518.CCALI_00435	4.85e-05	57.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SRR25158456_k127_1800288_0	234267.Acid_5274	2.376e-176	559.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158456_k127_1804251_3	314285.KT71_18237	3.985e-26	113.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1J4SK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158456_k127_1804251_1	204669.Acid345_4649	1.147e-45	169.0	COG0521@1|root,COG0521@2|Bacteria,3Y504@57723|Acidobacteria,2JJI8@204432|Acidobacteriia	204432|Acidobacteriia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158456_k127_1804251_0	290397.Adeh_2411	1.651e-129	425.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158456_k127_1804251_2	1071073.KI530540_gene3385	1.308e-35	148.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SRR25158456_k127_1811863_2	234267.Acid_0057	1.927e-138	457.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158456_k127_1811863_4	1267535.KB906767_gene806	1.664e-57	229.0	COG1629@1|root,COG4771@2|Bacteria	1267535.KB906767_gene806|-	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1811863_7	1449049.JONW01000008_gene595	6.754e-27	121.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158456_k127_1811863_5	1449049.JONW01000008_gene595	2.128e-50	203.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158456_k127_1811863_6	1449049.JONW01000008_gene595	5.336e-28	130.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158456_k127_1811863_1	649747.HMPREF0083_02381	3.063e-146	481.0	COG0671@1|root,COG0671@2|Bacteria,1USD9@1239|Firmicutes,4HAYV@91061|Bacilli,26W2H@186822|Paenibacillaceae	91061|Bacilli	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158456_k127_1811863_8	497964.CfE428DRAFT_0438	8.83e-13	83.0	COG1520@1|root,COG1572@1|root,COG3227@1|root,COG3391@1|root,COG4782@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG3391@2|Bacteria,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	DUF900,FTP,Peptidase_M36
SRR25158456_k127_1811863_0	1046714.AMRX01000006_gene2346	3.966e-149	517.0	COG2372@1|root,COG5276@1|root,COG2372@2|Bacteria,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria,46D9Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
SRR25158456_k127_1811863_3	715451.ambt_03875	2.361e-135	471.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1R1M5@1224|Proteobacteria,1RQBW@1236|Gammaproteobacteria,465Y0@72275|Alteromonadaceae	1236|Gammaproteobacteria	A	Protein conserved in bacteria	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
SRR25158456_k127_1811863_9	1283287.KB822583_gene2833	1.407e-10	76.0	COG2374@1|root,COG2885@1|root,COG3591@1|root,COG4222@1|root,COG2374@2|Bacteria,COG2885@2|Bacteria,COG3591@2|Bacteria,COG4222@2|Bacteria,2I59W@201174|Actinobacteria	201174|Actinobacteria	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
SRR25158456_k127_181370_2	338963.Pcar_2000	1.344e-86	293.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,43S11@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Protein of unknown function (DUF933)	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158456_k127_181370_3	1163617.SCD_n01288	1.076e-70	250.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria	28216|Betaproteobacteria	F	belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase,HTH_6,SIS
SRR25158456_k127_181370_5	448385.sce0444	8.521e-26	113.0	COG1846@1|root,COG1846@2|Bacteria,1RKAV@1224|Proteobacteria,42VFQ@68525|delta/epsilon subdivisions,2WRWP@28221|Deltaproteobacteria,2YV9F@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158456_k127_181370_6	1242864.D187_000936	3.981e-21	109.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_181370_1	1242864.D187_000937	7.923e-95	321.0	COG4711@1|root,COG4711@2|Bacteria,1R9Y5@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2391
SRR25158456_k127_181370_8	1380393.JHVP01000007_gene4466	2.769e-06	57.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria,4EUM4@85013|Frankiales	201174|Actinobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158456_k127_181370_7	491952.Mar181_0175	2.544e-11	70.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,1XJ8U@135619|Oceanospirillales	135619|Oceanospirillales	K	Response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_181370_0	748247.AZKH_4462	7.406e-144	464.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,2KXXF@206389|Rhodocyclales	206389|Rhodocyclales	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158456_k127_181370_4	159087.Daro_3700	5.012e-50	181.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VIIQ@28216|Betaproteobacteria,2KYDV@206389|Rhodocyclales	206389|Rhodocyclales	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158456_k127_181404_0	1174528.JH992898_gene2473	1.297e-210	717.0	COG3209@1|root,COG3209@2|Bacteria,1G4PY@1117|Cyanobacteria	1117|Cyanobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SRR25158456_k127_181598_2	1034769.KB910518_gene924	5.562e-11	72.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,4HS5J@91061|Bacilli,26X6Y@186822|Paenibacillaceae	91061|Bacilli	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2,zinc_ribbon_2
SRR25158456_k127_181598_1	448385.sce0038	8.006e-50	194.0	COG0393@1|root,COG0515@1|root,COG0393@2|Bacteria,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439IS@68525|delta/epsilon subdivisions,2X4V7@28221|Deltaproteobacteria,2YZNY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158456_k127_181598_0	266117.Rxyl_2946	1.25e-103	359.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158456_k127_1817053_7	1444306.JFZC01000012_gene2040	2.183e-06	55.0	COG4767@1|root,COG4767@2|Bacteria,1VK3A@1239|Firmicutes,4HPCD@91061|Bacilli	91061|Bacilli	V	VanZ like family	vanZ	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158456_k127_1817053_1	521098.Aaci_0535	9.46e-38	162.0	COG0346@1|root,COG0346@2|Bacteria,1V6K2@1239|Firmicutes,4HJ55@91061|Bacilli	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158456_k127_1817053_2	926566.Terro_0050	4.646e-33	133.0	COG0640@1|root,COG0640@2|Bacteria,3Y7J1@57723|Acidobacteria,2JMRU@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158456_k127_1817053_6	234267.Acid_6206	2.335e-11	75.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria	57723|Acidobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
SRR25158456_k127_1817053_4	309801.trd_0665	4.651e-18	94.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,27Z8D@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
SRR25158456_k127_1817053_5	579137.Metvu_1421	9.328e-14	81.0	COG3815@1|root,arCOG03949@2157|Archaea,2XYKM@28890|Euryarchaeota,23R0V@183939|Methanococci	183939|Methanococci	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
SRR25158456_k127_1817053_3	903818.KI912268_gene2000	5.027e-32	135.0	COG0745@1|root,COG0745@2|Bacteria	903818.KI912268_gene2000|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1817053_0	1379270.AUXF01000003_gene3584	1.121e-236	749.0	COG3653@1|root,COG3653@2|Bacteria,1ZTDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
SRR25158456_k127_181772_1	1230476.C207_03722	2.627e-89	302.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TYVX@28211|Alphaproteobacteria,3JX48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158456_k127_181772_6	913325.N799_01125	1.25e-06	60.0	COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria,1X7ZH@135614|Xanthomonadales	135614|Xanthomonadales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158456_k127_181772_4	324925.Ppha_2781	1.252e-38	151.0	COG0400@1|root,COG0400@2|Bacteria,1FF1R@1090|Chlorobi	1090|Chlorobi	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
SRR25158456_k127_181772_2	118173.KB235914_gene3902	4.248e-75	259.0	COG1215@1|root,COG1215@2|Bacteria,1G5YB@1117|Cyanobacteria,1HB60@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_181772_0	1192034.CAP_3083	6.727e-143	477.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2YTX0@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_181772_3	661478.OP10G_3757	1.611e-63	234.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,CHASE5,GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_181772_5	1144275.COCOR_00431	5.148e-38	149.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	mauD	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,HEAT_2,Redoxin
SRR25158456_k127_1819153_1	1283283.ATXA01000014_gene3617	2.42e-70	255.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158456_k127_1819153_0	234267.Acid_2493	1.29e-129	432.0	COG0457@1|root,COG0457@2|Bacteria,3Y46H@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1819153_10	714943.Mucpa_5678	8.281e-11	71.0	2CFIP@1|root,2ZW2J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1819153_8	714943.Mucpa_5678	9.198e-16	85.0	2CFIP@1|root,2ZW2J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1819153_2	204669.Acid345_3132	5.124e-43	162.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158456_k127_1819153_5	1396418.BATQ01000098_gene6019	8.037e-30	130.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158456_k127_1819153_9	204669.Acid345_1424	4.509e-14	83.0	COG2764@1|root,COG2764@2|Bacteria,3Y4WV@57723|Acidobacteria,2JK5P@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158456_k127_1819153_4	330214.NIDE3686	3.606e-36	141.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158456_k127_1819153_7	290397.Adeh_1235	1.923e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales	28221|Deltaproteobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158456_k127_1819153_6	1312959.KI914687_gene2623	1.063e-28	130.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,1W98E@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158456_k127_1819153_3	365046.Rta_16960	1.977e-38	147.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158456_k127_1830196_3	882083.SacmaDRAFT_5145	3.594e-11	76.0	COG4995@1|root,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4E0JJ@85010|Pseudonocardiales	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158456_k127_1830196_0	298654.FraEuI1c_5680	1.994e-206	694.0	2F32K@1|root,2ZBI3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1830196_1	298654.FraEuI1c_5681	1.669e-165	549.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	yidF	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158456_k127_1837047_7	204669.Acid345_3258	2.286e-19	94.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria,2JJXU@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158456_k127_1837047_6	195253.Syn6312_2618	2.852e-29	128.0	COG0681@1|root,COG0681@2|Bacteria,1G54H@1117|Cyanobacteria,1GZ4P@1129|Synechococcus	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB2	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158456_k127_1837047_1	1144275.COCOR_05743	5.535e-79	286.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
SRR25158456_k127_1837047_3	1382306.JNIM01000001_gene897	3.995e-51	196.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158456_k127_1837047_5	420246.GTNG_2765	1.286e-33	148.0	COG0265@1|root,COG0265@2|Bacteria,1UYZJ@1239|Firmicutes,4HFHN@91061|Bacilli,1WHAK@129337|Geobacillus	91061|Bacilli	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158456_k127_1837047_9	436229.JOEH01000015_gene6032	1.274e-08	68.0	COG0654@1|root,COG1716@1|root,COG0654@2|Bacteria,COG1716@2|Bacteria,2I9P3@201174|Actinobacteria,2NKMN@228398|Streptacidiphilus	201174|Actinobacteria	CHT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158456_k127_1837047_8	631362.Thi970DRAFT_01351	3.439e-12	76.0	COG1716@1|root,COG1716@2|Bacteria,1RHU9@1224|Proteobacteria,1S7XI@1236|Gammaproteobacteria,1WZMY@135613|Chromatiales	135613|Chromatiales	T	PFAM FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
SRR25158456_k127_1837047_4	1123277.KB893239_gene1180	7.146e-47	184.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,47PE8@768503|Cytophagia	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
SRR25158456_k127_1837047_2	1242864.D187_010069	2.585e-57	221.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
SRR25158456_k127_1837047_10	1499967.BAYZ01000184_gene4554	0.0001275	53.0	COG4995@1|root,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_1837047_0	671143.DAMO_2095	1.031e-116	402.0	COG0744@1|root,COG0744@2|Bacteria,2NNMB@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158456_k127_1838145_5	344747.PM8797T_07137	6.927e-60	216.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,2IXF2@203682|Planctomycetes	203682|Planctomycetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
SRR25158456_k127_1838145_11	926560.KE387025_gene4140	0.0005702	50.0	2C9T3@1|root,32RPV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1838145_7	56110.Oscil6304_2505	1.183e-16	86.0	COG2886@1|root,COG2886@2|Bacteria,1G7YG@1117|Cyanobacteria,1HCR8@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
SRR25158456_k127_1838145_2	448385.sce5225	2.552e-159	539.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,4389V@68525|delta/epsilon subdivisions,2X3J8@28221|Deltaproteobacteria,2YWAY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158456_k127_1838145_9	1206732.BAGD01000019_gene63	2.967e-12	75.0	COG1309@1|root,COG1309@2|Bacteria,2IQIX@201174|Actinobacteria,4G2MQ@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158456_k127_1838145_8	1122180.Lokhon_02835	3.096e-15	88.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,2P8J6@245186|Loktanella	28211|Alphaproteobacteria	MU	Outer membrane efflux protein	bepC	-	-	ko:K12340,ko:K12535	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00327,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SRR25158456_k127_1838145_6	1254432.SCE1572_10340	2.952e-30	131.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WK41@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR25158456_k127_1838145_0	448385.sce1628	0.0	1060.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158456_k127_1838145_1	1245469.S58_36280	5.373e-170	552.0	2EPJD@1|root,33H61@2|Bacteria,1P9VX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1838145_3	1123278.KB893573_gene6187	1.308e-108	383.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47NMM@768503|Cytophagia	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
SRR25158456_k127_1838145_10	67356.KL575602_gene6515	2.743e-10	74.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria	201174|Actinobacteria	T	Signal transduction protein with Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,NACHT
SRR25158456_k127_1838145_4	448385.sce3873	3.162e-107	383.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,SIR2_2
SRR25158456_k127_1849599_3	1297742.A176_06046	1.221e-58	216.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YXY6@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15,4.1.1.86	ko:K01580,ko:K13745	ko00250,ko00260,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00260,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466,R07650	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158456_k127_1849599_0	443143.GM18_3586	1.255e-203	648.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,43TA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRR25158456_k127_1849599_2	237368.SCABRO_00310	5.717e-80	290.0	COG2027@1|root,COG2027@2|Bacteria,2IYAC@203682|Planctomycetes	203682|Planctomycetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158456_k127_1849599_4	1123242.JH636434_gene4039	2.734e-52	195.0	COG1234@1|root,COG1234@2|Bacteria,2IWSW@203682|Planctomycetes	203682|Planctomycetes	S	of the beta-lactamase	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158456_k127_1849599_5	351160.RCIX924	2.697e-32	136.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158456_k127_1849599_7	903818.KI912268_gene3191	3.237e-18	93.0	COG4911@1|root,COG4911@2|Bacteria,3Y4VB@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158456_k127_1849599_6	204669.Acid345_4505	3.556e-25	107.0	COG0236@1|root,COG0236@2|Bacteria,3Y54V@57723|Acidobacteria,2JJPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158456_k127_1849599_1	289376.THEYE_A0103	1.436e-108	357.0	COG0304@1|root,COG0304@2|Bacteria,3J0DH@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_1858188_1	215803.DB30_5770	5.415e-83	308.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Pkinase_Tyr,WD40
SRR25158456_k127_1858188_3	234267.Acid_1209	1.178e-50	186.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158456_k127_1858188_4	1192034.CAP_1954	6.681e-10	71.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_1954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1858188_2	929562.Emtol_0801	1.915e-75	260.0	COG1816@1|root,COG1816@2|Bacteria,4NJ8S@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158456_k127_1858209_2	572480.Arnit_1912	1.927e-14	85.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,43AME@68525|delta/epsilon subdivisions,2YT20@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_1858209_1	381666.H16_A1278	2.649e-25	119.0	COG0457@1|root,COG2114@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VSSJ@28216|Betaproteobacteria,1K5FA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,SAM_1,TPR_12,TPR_8,Trans_reg_C
SRR25158456_k127_1858209_0	234267.Acid_1914	3.057e-157	512.0	COG0304@1|root,COG0304@2|Bacteria,3Y43C@57723|Acidobacteria	57723|Acidobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_186421_0	379066.GAU_0014	1.69e-96	328.0	COG2270@1|root,COG2270@2|Bacteria,1ZSZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158456_k127_186421_1	68199.JNZO01000004_gene1660	1.222e-70	245.0	COG0684@1|root,COG0684@2|Bacteria,2I9PH@201174|Actinobacteria	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SRR25158456_k127_186421_3	349521.HCH_05597	2.683e-30	123.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria,1XKS3@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158456_k127_186421_2	1117108.PAALTS15_09640	5.457e-44	169.0	COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,26SUB@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
SRR25158456_k127_1880072_1	330214.NIDE1826	2.495e-21	108.0	COG0654@1|root,COG0654@2|Bacteria,3J16C@40117|Nitrospirae	40117|Nitrospirae	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158456_k127_1880072_0	29581.BW37_04478	4.339e-144	483.0	COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria,1N0QS@1224|Proteobacteria	1224|Proteobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADC,Amino_oxidase,NAD_binding_8
SRR25158456_k127_1880072_2	1122604.JONR01000007_gene2927	2.94e-11	74.0	COG3349@1|root,COG3349@2|Bacteria,1QVG4@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	-	-	-	-	-	-	-	-	-	-	-	-	ADC
SRR25158456_k127_189563_2	1485545.JQLW01000007_gene735	1.329e-21	104.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	cNMP_binding
SRR25158456_k127_189563_1	1040986.ATYO01000007_gene1068	4.543e-47	176.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,43IDN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.31,3.5.1.88	ko:K01450,ko:K01462	ko00270,ko00630,map00270,map00630	-	R00653	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	Pep_deformylase
SRR25158456_k127_189563_4	511062.GU3_01280	5.406e-14	82.0	COG1018@1|root,COG1018@2|Bacteria,1RAS4@1224|Proteobacteria	1224|Proteobacteria	C	oxidoreductase FAD NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
SRR25158456_k127_189563_5	477974.Daud_2032	1.935e-13	83.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC4@186801|Clostridia,262GR@186807|Peptococcaceae	186801|Clostridia	EH	PFAM Aminotransferase, class IV	ilvE2	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158456_k127_189563_0	1038858.AXBA01000016_gene1940	5.369e-56	212.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,3EYR5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158456_k127_189563_3	204773.HEAR0611	5.082e-15	76.0	COG2865@1|root,COG2865@2|Bacteria,1R4MD@1224|Proteobacteria,2VU31@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
SRR25158456_k127_189563_6	1449050.JNLE01000005_gene4183	1.286e-11	77.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158456_k127_1908275_2	351607.Acel_1860	3.767e-64	237.0	COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4ERYH@85013|Frankiales	201174|Actinobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158456_k127_1908275_1	1267535.KB906767_gene5039	6.112e-86	297.0	COG0520@1|root,COG0520@2|Bacteria,3Y632@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158456_k127_1908275_0	1255043.TVNIR_1740	2.635e-142	470.0	COG0457@1|root,COG0457@2|Bacteria,1R1XZ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
SRR25158456_k127_1908275_3	1267535.KB906767_gene3956	1.626e-40	152.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria,2JINW@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158456_k127_1909450_7	1242864.D187_004666	1.243e-10	71.0	COG0457@1|root,COG0457@2|Bacteria	1242864.D187_004666|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1909450_6	1356852.N008_20540	3.796e-22	107.0	2DTU1@1|root,33MMF@2|Bacteria,4NWD8@976|Bacteroidetes,47SX0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1909450_4	1123073.KB899242_gene1384	5.497e-39	152.0	COG0454@1|root,COG0456@2|Bacteria,1RDH4@1224|Proteobacteria,1SCMT@1236|Gammaproteobacteria,1X66P@135614|Xanthomonadales	135614|Xanthomonadales	K	acetyltransferase	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158456_k127_1909450_0	404589.Anae109_4348	1.452e-150	488.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158456_k127_1909450_3	945713.IALB_2119	5.926e-40	154.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158456_k127_1909450_5	640081.Dsui_3050	1.864e-29	121.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KWN5@206389|Rhodocyclales	206389|Rhodocyclales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158456_k127_1909450_2	502025.Hoch_6837	4.48e-52	196.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR25158456_k127_1909450_8	1530186.JQEY01000003_gene2206	5.007e-05	50.0	2CK2Q@1|root,303GN@2|Bacteria,1RG44@1224|Proteobacteria,2U8BW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1909450_1	1267533.KB906742_gene675	8.219e-56	210.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y6UN@57723|Acidobacteria	57723|Acidobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1909545_6	1123386.AUIW01000009_gene1812	1.821e-21	99.0	COG1848@1|root,COG1848@2|Bacteria,1WKJ4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1909545_0	243231.GSU1636	2.036e-176	564.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158456_k127_1909545_5	291985.CCSI01000002_gene1680	1.443e-43	168.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1909545_1	635013.TherJR_0997	9.54e-151	514.0	COG0395@1|root,COG5001@1|root,COG5002@1|root,COG0395@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9
SRR25158456_k127_1909545_3	861299.J421_1115	2.7e-79	273.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1909545_2	1303518.CCALI_01109	3.844e-94	319.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158456_k127_1909545_8	234267.Acid_0699	7.143e-09	62.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158456_k127_1909545_4	215803.DB30_0760	1.203e-71	259.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,42PPN@68525|delta/epsilon subdivisions,2WK8S@28221|Deltaproteobacteria,2Z1ED@29|Myxococcales	28221|Deltaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
SRR25158456_k127_1909545_7	290397.Adeh_0729	9.033e-19	94.0	COG1073@1|root,COG1073@2|Bacteria,1PBV5@1224|Proteobacteria,433TK@68525|delta/epsilon subdivisions,2X3EJ@28221|Deltaproteobacteria,2YVQG@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
SRR25158456_k127_1920955_3	1146883.BLASA_0999	0.0001412	55.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD
SRR25158456_k127_1920955_1	985255.APHJ01000024_gene1172	3.944e-22	112.0	COG3391@1|root,COG3391@2|Bacteria,4NK97@976|Bacteroidetes,1HYP5@117743|Flavobacteriia,2P7C8@244698|Gillisia	976|Bacteroidetes	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
SRR25158456_k127_1920955_2	1415754.JQMK01000002_gene3578	8.197e-12	78.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	BatA,CARDB,F5_F8_type_C,HemolysinCabind,Laminin_G_3,NIDO,VWA_2
SRR25158456_k127_1920955_0	246197.MXAN_5218	4.38e-78	285.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT,PMT_2
SRR25158456_k127_1921535_6	1121920.AUAU01000002_gene2022	2.347e-10	72.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000002_gene2022|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1921535_0	448385.sce2453	3.13e-307	954.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
SRR25158456_k127_1921535_1	1192034.CAP_6426	3.321e-75	262.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZAP@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158456_k127_1921535_3	485913.Krac_9819	2.546e-50	188.0	2DQBG@1|root,335T7@2|Bacteria,2G96K@200795|Chloroflexi	200795|Chloroflexi	C	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	-	-	-	-	-	-	-	-	-	-	GRDB
SRR25158456_k127_1921535_4	1120973.AQXL01000135_gene1319	4.808e-36	139.0	COG1225@1|root,COG1225@2|Bacteria,1V6MU@1239|Firmicutes,4HK8J@91061|Bacilli,27A0F@186823|Alicyclobacillaceae	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158456_k127_1921535_5	1120973.AQXL01000135_gene1318	5.245e-12	74.0	COG1225@1|root,COG1225@2|Bacteria,1VGP9@1239|Firmicutes,4HQ3V@91061|Bacilli,27AF7@186823|Alicyclobacillaceae	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158456_k127_1921535_2	869210.Marky_1341	1.108e-51	194.0	COG1281@1|root,COG1281@2|Bacteria,1WJ1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SRR25158456_k127_1923444_1	1242864.D187_006772	1.209e-79	276.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,43777@68525|delta/epsilon subdivisions,2X9UJ@28221|Deltaproteobacteria,2Z0XS@29|Myxococcales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
SRR25158456_k127_1923444_5	935840.JAEQ01000002_gene3277	3.888e-33	141.0	2E5IZ@1|root,330AA@2|Bacteria,1N9JX@1224|Proteobacteria,2UVN3@28211|Alphaproteobacteria,43QQP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1923444_2	639030.JHVA01000001_gene1931	2.982e-57	205.0	COG3832@1|root,COG3832@2|Bacteria,3Y7X4@57723|Acidobacteria,2JNZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_1923444_3	1254432.SCE1572_31280	1.76e-47	174.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,430Y1@68525|delta/epsilon subdivisions,2WVU4@28221|Deltaproteobacteria,2YVFD@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158456_k127_1923444_0	945713.IALB_3187	7.611e-145	494.0	COG0012@1|root,COG0012@2|Bacteria	2|Bacteria	J	GTP binding	ychF	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158456_k127_1923444_7	1121440.AUMA01000003_gene2934	5.06e-06	60.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2MDBG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158456_k127_1923444_4	296591.Bpro_0676	7.624e-41	158.0	2DZKR@1|root,32VDB@2|Bacteria,1RBUG@1224|Proteobacteria,2VQA7@28216|Betaproteobacteria,4ADGA@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1925217_2	1047013.AQSP01000100_gene599	1.271e-15	91.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_1925217_3	761193.Runsl_0782	3.174e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_1925217_0	1047013.AQSP01000131_gene1840	8.429e-102	358.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158456_k127_1925217_1	1047013.AQSP01000123_gene1525	5.214e-84	315.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158456_k127_1935827_3	1125863.JAFN01000001_gene2394	1.61e-08	61.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,42TZ7@68525|delta/epsilon subdivisions,2WR0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_1935827_0	1158292.JPOE01000002_gene2954	8.527e-158	515.0	COG1032@1|root,COG1032@2|Bacteria,1NP6A@1224|Proteobacteria	1224|Proteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
SRR25158456_k127_1935827_1	880072.Desac_1962	2.379e-41	175.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CF9@68525|delta/epsilon subdivisions,2X7QB@28221|Deltaproteobacteria,2MS55@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K16087,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.2,1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_1935827_2	1038867.AXAY01000009_gene5736	2.858e-23	106.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2U6QG@28211|Alphaproteobacteria,3JYKK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158456_k127_193636_14	1192034.CAP_6791	2.044e-05	53.0	2C4KT@1|root,340PA@2|Bacteria,1NYVI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_193636_0	1121013.P873_00385	1.575e-191	612.0	COG0464@1|root,COG0464@2|Bacteria,1RCHW@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158456_k127_193636_13	1254432.SCE1572_07150	5.245e-06	57.0	2ESNI@1|root,33K73@2|Bacteria,1Q2MV@1224|Proteobacteria,4388I@68525|delta/epsilon subdivisions,2X3I7@28221|Deltaproteobacteria,2YW7A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
SRR25158456_k127_193636_4	794903.OPIT5_28655	9.291e-84	287.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,46T5T@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003,cNMP_binding
SRR25158456_k127_193636_15	1123252.ATZF01000001_gene1011	0.0003379	51.0	2DRFR@1|root,33BIP@2|Bacteria,1UBQS@1239|Firmicutes,4IN5S@91061|Bacilli,27CBE@186824|Thermoactinomycetaceae	91061|Bacilli	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	DUF454,PGPGW
SRR25158456_k127_193636_6	1385517.N800_06205	2.272e-61	220.0	COG0500@1|root,COG0500@2|Bacteria,1R947@1224|Proteobacteria,1SUF1@1236|Gammaproteobacteria,1X4RG@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158456_k127_193636_7	1089550.ATTH01000001_gene148	7.057e-58	220.0	2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_193636_9	518766.Rmar_0432	1.162e-27	119.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1FK9R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158456_k127_193636_12	1121930.AQXG01000001_gene1288	3.908e-11	77.0	COG2353@1|root,COG2353@2|Bacteria,4NTB0@976|Bacteroidetes,1IT3R@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158456_k127_193636_1	525904.Tter_2549	1.477e-128	434.0	COG3850@1|root,COG3850@2|Bacteria,2NS42@2323|unclassified Bacteria	2|Bacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
SRR25158456_k127_193636_3	479434.Sthe_0155	1.167e-84	285.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi,27XKP@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_193636_16	1304275.C41B8_10495	0.0005723	46.0	2DRB5@1|root,33B20@2|Bacteria,1NIFF@1224|Proteobacteria,1SGF4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158456_k127_193636_5	1121403.AUCV01000031_gene2839	2.681e-70	255.0	2DKWY@1|root,30NX3@2|Bacteria,1RBMB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
SRR25158456_k127_193636_11	153496.JNAB01000013_gene1169	1.919e-12	70.0	2ESJ3@1|root,33K3T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158456_k127_193636_8	1324957.K933_02771	7.937e-32	131.0	COG0717@1|root,arCOG04048@2157|Archaea,2XTSH@28890|Euryarchaeota,23S4X@183963|Halobacteria	183963|Halobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
SRR25158456_k127_193636_10	404589.Anae109_4262	1.051e-23	115.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WNCM@28221|Deltaproteobacteria,2Z20A@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158456_k127_193636_2	243231.GSU1331	4.127e-97	348.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,43SU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
SRR25158456_k127_1939685_2	1454004.AW11_00750	4.851e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1N4XB@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
SRR25158456_k127_1939685_0	1237149.C900_00889	4.347e-204	653.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158456_k127_1939685_1	204669.Acid345_1455	3.002e-118	398.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158456_k127_194151_1	1298593.TOL_3669	1.689e-24	113.0	29W19@1|root,30HJP@2|Bacteria,1R60N@1224|Proteobacteria,1S21W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_194151_0	1122604.JONR01000018_gene1066	2.571e-169	559.0	COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QWC6@1224|Proteobacteria,1RPDJ@1236|Gammaproteobacteria,1X4ZV@135614|Xanthomonadales	135614|Xanthomonadales	COT	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Pyr_redox_3,cNMP_binding
SRR25158456_k127_1952575_10	1121091.AUMP01000054_gene3367	1.509e-09	59.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1952575_9	83219.PM02_18360	3.084e-16	91.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,3ZW4T@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH
SRR25158456_k127_1952575_6	1267533.KB906735_gene5073	4.003e-48	191.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria,2JK7Z@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158456_k127_1952575_5	861299.J421_2070	7.993e-55	195.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
SRR25158456_k127_1952575_7	1210884.HG799462_gene7921	2.499e-26	112.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SRR25158456_k127_1952575_2	448385.sce8724	5.853e-166	537.0	COG3093@1|root,COG3800@1|root,COG3093@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,43B2B@68525|delta/epsilon subdivisions,2X6GC@28221|Deltaproteobacteria,2Z3AZ@29|Myxococcales	28221|Deltaproteobacteria	K	Pfam:DUF955	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_3,HTH_31,Peptidase_M78
SRR25158456_k127_1952575_0	1288484.APCS01000012_gene947	9.567e-213	673.0	COG2225@1|root,COG2225@2|Bacteria,1WIVZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158456_k127_1952575_1	1128421.JAGA01000004_gene2609	1.643e-211	665.0	COG2224@1|root,COG2224@2|Bacteria	2|Bacteria	C	isocitrate lyase activity	aceA	GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b4015,iAF1260.b4015,iB21_1397.B21_03847,iBWG_1329.BWG_3671,iE2348C_1286.E2348C_4318,iEC042_1314.EC042_4377,iEC55989_1330.EC55989_4500,iECABU_c1320.ECABU_c45310,iECBD_1354.ECBD_4022,iECB_1328.ECB_03887,iECDH10B_1368.ECDH10B_4204,iECDH1ME8569_1439.ECDH1ME8569_3871,iECD_1391.ECD_03887,iECED1_1282.ECED1_4722,iECIAI1_1343.ECIAI1_4235,iECIAI39_1322.ECIAI39_4401,iECNA114_1301.ECNA114_4164,iECO103_1326.ECO103_4759,iECO111_1330.ECO111_4827,iECO26_1355.ECO26_5119,iECP_1309.ECP_4225,iECSE_1348.ECSE_4300,iECSF_1327.ECSF_3865,iECUMN_1333.ECUMN_4541,iECW_1372.ECW_m4374,iEKO11_1354.EKO11_4310,iETEC_1333.ETEC_4270,iEcDH1_1363.EcDH1_3982,iEcE24377_1341.EcE24377A_4557,iEcHS_1320.EcHS_A4249,iEcSMS35_1347.EcSMS35_4469,iEcolC_1368.EcolC_4015,iJN746.PP_4116,iJO1366.b4015,iJR904.b4015,iLF82_1304.LF82_0012,iNRG857_1313.NRG857_20015,iSDY_1059.SDY_4328,iUMNK88_1353.UMNK88_4859,iWFL_1372.ECW_m4374,iY75_1357.Y75_RS20880	ICL
SRR25158456_k127_1952575_4	1396141.BATP01000023_gene600	5.676e-66	237.0	COG0545@1|root,COG0545@2|Bacteria,46U5S@74201|Verrucomicrobia,2IVK3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
SRR25158456_k127_1952575_3	489825.LYNGBM3L_52760	3.265e-155	507.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1H7T7@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158456_k127_195362_7	331113.SNE_A09700	2.626e-20	92.0	COG2154@1|root,COG2154@2|Bacteria,2JGH7@204428|Chlamydiae	204428|Chlamydiae	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158456_k127_195362_9	985665.HPL003_26400	2.515e-05	51.0	2DJVE@1|root,307G4@2|Bacteria,1U1MD@1239|Firmicutes,4IB3T@91061|Bacilli,273NG@186822|Paenibacillaceae	91061|Bacilli	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158456_k127_195362_3	335543.Sfum_2372	2.069e-81	287.0	COG0535@1|root,COG0535@2|Bacteria,1MYFX@1224|Proteobacteria,42SB0@68525|delta/epsilon subdivisions,2WPF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158456_k127_195362_6	335543.Sfum_2373	6.047e-30	129.0	COG1117@1|root,COG1117@2|Bacteria,1NMB4@1224|Proteobacteria,42XIZ@68525|delta/epsilon subdivisions,2WTEA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_195362_10	304371.MCP_0882	8.84e-05	52.0	COG0681@1|root,arCOG01740@2157|Archaea	2157|Archaea	U	Signal peptidase	lepW	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158456_k127_195362_5	498848.TaqDRAFT_5234	6.154e-38	164.0	COG1361@1|root,COG3420@1|root,COG1361@2|Bacteria,COG3420@2|Bacteria,1WNFU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11
SRR25158456_k127_195362_4	1123392.AQWL01000002_gene1743	5.558e-61	226.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,2VIKI@28216|Betaproteobacteria,1KSXA@119069|Hydrogenophilales	119069|Hydrogenophilales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_195362_2	1267535.KB906767_gene2297	1.23e-85	288.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria,2JMQ5@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_195362_1	1267535.KB906767_gene2296	4.191e-86	323.0	COG4585@1|root,COG4585@2|Bacteria,3Y59R@57723|Acidobacteria	2|Bacteria	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA_3,PAS,PAS_9,Pkinase
SRR25158456_k127_195362_0	1095769.CAHF01000011_gene2157	1.718e-157	513.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2VIAZ@28216|Betaproteobacteria,478Q4@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158456_k127_195362_8	313625.BL107_07029	4.443e-19	100.0	COG3769@1|root,COG3769@2|Bacteria,1G4FD@1117|Cyanobacteria,1GYM3@1129|Synechococcus	1117|Cyanobacteria	S	hydrolase (HAD superfamily)	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
SRR25158456_k127_1954373_4	1205680.CAKO01000038_gene1726	2.951e-36	152.0	COG0477@1|root,COG2814@2|Bacteria,1MW1P@1224|Proteobacteria	1224|Proteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_1954373_2	1121033.AUCF01000033_gene3627	9.982e-152	509.0	COG0492@1|root,COG0492@2|Bacteria,1MXI0@1224|Proteobacteria,2TUAR@28211|Alphaproteobacteria,2JRFF@204441|Rhodospirillales	204441|Rhodospirillales	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
SRR25158456_k127_1954373_7	1123487.KB892834_gene2803	1.514e-18	99.0	COG1246@1|root,COG1595@1|root,COG1246@2|Bacteria,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,2VRKX@28216|Betaproteobacteria,2KWKE@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_1954373_5	521719.ATXQ01000007_gene1147	1.13e-26	115.0	COG3597@1|root,COG3597@2|Bacteria,1RKKI@1224|Proteobacteria,1S7SS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_1954373_1	509190.Cseg_2578	3.073e-184	589.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,2TT4B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_1954373_0	509190.Cseg_2581	1.49e-281	894.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2U0ZY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158456_k127_1954373_3	1229172.JQFA01000002_gene2806	9.154e-144	468.0	COG0057@1|root,COG0057@2|Bacteria,1G0ZV@1117|Cyanobacteria,1HE62@1150|Oscillatoriales	1117|Cyanobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap3	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158456_k127_1954373_6	330214.NIDE3702	1.356e-20	106.0	COG0306@1|root,COG0306@2|Bacteria,3J1D1@40117|Nitrospirae	40117|Nitrospirae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158456_k127_1956129_0	1089547.KB913013_gene2767	4.42e-213	676.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158456_k127_1956129_1	204669.Acid345_4432	1.095e-160	530.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,3Y61X@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD_5
SRR25158456_k127_1956129_2	661478.OP10G_4294	5.073e-62	225.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158456_k127_1957757_0	1254432.SCE1572_50235	6.173e-59	227.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,42YY5@68525|delta/epsilon subdivisions,2WPYC@28221|Deltaproteobacteria,2YUGH@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158456_k127_1957757_2	869213.JCM21142_104243	4.918e-15	90.0	COG2340@1|root,COG2340@2|Bacteria,4P06D@976|Bacteroidetes	976|Bacteroidetes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158456_k127_1957757_1	765910.MARPU_04185	2.999e-55	218.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
SRR25158456_k127_1968749_6	240292.Ava_0314	2.517e-08	66.0	COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,1HUA6@1161|Nostocales	1117|Cyanobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158456_k127_1968749_3	56110.Oscil6304_0829	2.073e-75	267.0	COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_1968749_2	314230.DSM3645_22174	7.994e-114	378.0	COG2081@1|root,COG2081@2|Bacteria,2IWW4@203682|Planctomycetes	203682|Planctomycetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158456_k127_1968749_4	1278073.MYSTI_01846	5.677e-50	184.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158456_k127_1968749_5	1340493.JNIF01000003_gene4229	2.389e-35	143.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
SRR25158456_k127_1968749_0	1047013.AQSP01000125_gene2627	3.622e-235	753.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	mca	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	NPCBM_assoc,PIG-L
SRR25158456_k127_1968749_1	504472.Slin_1640	4.298e-179	578.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158456_k127_1975679_0	706587.Desti_5232	5.745e-137	469.0	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	CP_1034	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
SRR25158456_k127_1975679_1	1183438.GKIL_3395	1.933e-134	460.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SRR25158456_k127_1975679_4	502025.Hoch_1576	1.589e-56	204.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158456_k127_1975679_3	248742.XP_005651253.1	1.462e-127	436.0	COG0156@1|root,KOG1359@2759|Eukaryota,37PAF@33090|Viridiplantae	33090|Viridiplantae	E	2-amino-3-ketobutyrate coenzyme A ligase	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_1975679_5	639030.JHVA01000001_gene3108	1.198e-55	201.0	COG5553@1|root,COG5553@2|Bacteria,3Y975@57723|Acidobacteria,2JNQM@204432|Acidobacteriia	204432|Acidobacteriia	S	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
SRR25158456_k127_1975679_2	240015.ACP_2260	7.203e-132	431.0	COG0104@1|root,COG0104@2|Bacteria,3Y2Z9@57723|Acidobacteria,2JIIV@204432|Acidobacteriia	204432|Acidobacteriia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158456_k127_1978343_3	315730.BcerKBAB4_4350	7.966e-22	95.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus	91061|Bacilli	C	Electron transfer flavoprotein	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158456_k127_1978343_1	1382359.JIAL01000001_gene3047	3.007e-47	179.0	COG4464@1|root,COG4464@2|Bacteria,3Y4AS@57723|Acidobacteria,2JJ14@204432|Acidobacteriia	204432|Acidobacteriia	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158456_k127_1978343_0	1047013.AQSP01000112_gene392	1.598e-98	349.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SRR25158456_k127_1978343_4	521045.Kole_0012	3.704e-17	92.0	COG1596@1|root,COG1596@2|Bacteria,2GCU6@200918|Thermotogae	200918|Thermotogae	M	polysaccharide export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SRR25158456_k127_1978343_2	2340.JV46_20030	9.791e-25	120.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,1J709@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158456_k127_1980344_7	379066.GAU_0215	2.447e-30	132.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158456_k127_1980344_5	1122169.AREN01000008_gene893	2.248e-42	164.0	COG0693@1|root,COG0693@2|Bacteria,1RJIV@1224|Proteobacteria,1S661@1236|Gammaproteobacteria,1JGK7@118969|Legionellales	118969|Legionellales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158456_k127_1980344_6	595460.RRSWK_04959	6.344e-31	137.0	COG1361@1|root,COG1404@1|root,COG1572@1|root,COG2133@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG4675@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG1572@2|Bacteria,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4675@2|Bacteria,2IYDY@203682|Planctomycetes	203682|Planctomycetes	QU	TIGRFAM autotransporter-associated beta strand repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,PA14,PATR
SRR25158456_k127_1980344_8	1122919.KB905633_gene465	3.237e-18	93.0	COG4675@1|root,COG4675@2|Bacteria,1VHKQ@1239|Firmicutes,4HVG0@91061|Bacilli,26XMT@186822|Paenibacillaceae	91061|Bacilli	S	Phage Tail Collar Domain	mdpB	-	-	-	-	-	-	-	-	-	-	-	Collar
SRR25158456_k127_1980344_9	1110502.TMO_0489	7.538e-18	86.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158456_k127_1980344_2	1214101.BN159_8030	2.093e-132	438.0	COG0304@1|root,COG0304@2|Bacteria,2H1NI@201174|Actinobacteria	201174|Actinobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_1980344_0	1110502.TMO_0484	7.015e-199	640.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158456_k127_1980344_1	1463921.JODF01000021_gene3335	1.477e-169	550.0	COG0318@1|root,COG0318@2|Bacteria,2I2RH@201174|Actinobacteria	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158456_k127_1980344_3	1110502.TMO_0484	7.441e-59	222.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158456_k127_1980344_4	1297742.A176_04443	8.664e-56	220.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158456_k127_198981_3	204669.Acid345_1550	1.797e-100	335.0	COG4307@1|root,COG4307@2|Bacteria,3Y69G@57723|Acidobacteria,2JM0B@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
SRR25158456_k127_198981_2	1267534.KB906755_gene4826	1.195e-113	390.0	COG1181@1|root,COG1181@2|Bacteria,3Y6Z0@57723|Acidobacteria,2JKPX@204432|Acidobacteriia	204432|Acidobacteriia	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR25158456_k127_198981_1	883158.HMPREF9140_01078	3.837e-129	424.0	COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,2FN1B@200643|Bacteroidia	976|Bacteroidetes	E	Aminotransferase, class I II	aspC	-	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_198981_0	1121920.AUAU01000004_gene813	6.924e-187	605.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria	57723|Acidobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
SRR25158456_k127_2009113_4	1121920.AUAU01000028_gene1372	8.731e-30	136.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_2009113_0	266265.Bxe_A0649	2.059e-72	251.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,1K3BF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	hemolysin III	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158456_k127_2009113_3	189425.PGRAT_21660	1.306e-42	172.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_2009113_5	1274.HX89_10580	3.598e-29	121.0	COG4290@1|root,COG4290@2|Bacteria,2IHPV@201174|Actinobacteria,1ZW6F@145357|Dermacoccaceae	201174|Actinobacteria	F	ribonuclease	-	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
SRR25158456_k127_2009113_6	930166.CD58_03755	1.614e-12	72.0	COG2732@1|root,COG2732@2|Bacteria,1QR1J@1224|Proteobacteria,1SU9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
SRR25158456_k127_2009113_1	391625.PPSIR1_23324	1.058e-64	241.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	ddpA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158456_k127_2009113_2	880073.Calab_3797	1.015e-44	173.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,HisKA_3,PAS_9,Reg_prop,Response_reg,SpoIIE,Y_Y_Y
SRR25158456_k127_2013873_1	498761.HM1_3028	3.05e-180	584.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158456_k127_2013873_3	1123073.KB899244_gene350	3.597e-93	316.0	COG0491@1|root,COG0491@2|Bacteria,1QBJF@1224|Proteobacteria,1T752@1236|Gammaproteobacteria,1X8SQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_2013873_6	378806.STAUR_3731	3.869e-06	56.0	2AJ25@1|root,319KF@2|Bacteria,1Q32B@1224|Proteobacteria,438SQ@68525|delta/epsilon subdivisions,2X9CK@28221|Deltaproteobacteria,2YXP8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2013873_4	1144275.COCOR_07305	4.092e-69	258.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158456_k127_2013873_5	1121428.DESHY_160010___1	7.888e-34	138.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,26214@186807|Peptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158456_k127_2013873_0	330214.NIDE1728	1.574e-229	733.0	COG0443@1|root,COG0443@2|Bacteria,3J0D2@40117|Nitrospirae	40117|Nitrospirae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158456_k127_2013873_2	234267.Acid_0734	5.519e-125	410.0	COG0484@1|root,COG0484@2|Bacteria,3Y33I@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158456_k127_2021083_3	1297742.A176_05463	4.646e-64	243.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SRR25158456_k127_2021083_1	391625.PPSIR1_28588	9.318e-113	382.0	COG1226@1|root,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158456_k127_2021083_4	595460.RRSWK_01547	3.189e-48	182.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563,ko:K10947	-	-	R07233	RC00003	ko00000,ko01000,ko03000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158456_k127_2021083_2	1254432.SCE1572_19565	3.957e-102	340.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,42UUC@68525|delta/epsilon subdivisions,2WQFQ@28221|Deltaproteobacteria,2YZP1@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158456_k127_2021083_0	1254432.SCE1572_45970	1.245e-134	437.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2WNTJ@28221|Deltaproteobacteria,2YZKR@29|Myxococcales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SRR25158456_k127_2021083_5	1189620.AJXL01000074_gene3244	9.513e-20	106.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia,2NSYB@237|Flavobacterium	976|Bacteroidetes	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2021083_6	401053.AciPR4_1526	3.173e-12	80.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
SRR25158456_k127_2027185_5	1122925.KB895381_gene3952	1.118e-21	98.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,26QZ3@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158456_k127_2027185_0	479432.Sros_4287	1.218e-180	600.0	COG1132@1|root,COG1413@1|root,COG1132@2|Bacteria,COG1413@2|Bacteria,2I6NK@201174|Actinobacteria	201174|Actinobacteria	V	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2027185_2	448385.sce6780	3.35e-64	226.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_2027185_6	293826.Amet_3741	1.758e-05	52.0	2ECY4@1|root,336V8@2|Bacteria,1VJG0@1239|Firmicutes,24SHD@186801|Clostridia	186801|Clostridia	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158456_k127_2027185_1	234267.Acid_1531	2.239e-163	534.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158456_k127_2027185_3	1191523.MROS_0794	8.883e-55	207.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	1.14.19.49,1.3.1.101,1.3.7.11,5.5.1.18	ko:K06444,ko:K14257,ko:K17830	ko00253,ko00404,ko00564,ko00906,ko01057,ko01100,ko01110,ko01130,map00253,map00404,map00564,map00906,map01057,map01100,map01110,map01130	M00790,M00823	R05456,R06960,R06963,R07840,R10325,R10326,R10331,R11106,R11478	RC00949,RC01612,RC03134	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2,Trp_halogenase
SRR25158456_k127_2027185_4	76114.ebA6810	9.584e-54	200.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KUHC@206389|Rhodocyclales	206389|Rhodocyclales	I	Squalene synthase HpnD	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158456_k127_2047970_8	1185876.BN8_02463	9.647e-20	98.0	COG2989@1|root,COG2989@2|Bacteria,4NH3J@976|Bacteroidetes,47MU1@768503|Cytophagia	976|Bacteroidetes	T	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
SRR25158456_k127_2047970_4	404589.Anae109_2961	1.884e-31	132.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P6Q@68525|delta/epsilon subdivisions,2WKPS@28221|Deltaproteobacteria,2YXDB@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2047970_2	1117943.SFHH103_02774	9.821e-71	250.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158456_k127_2047970_9	658659.HMPREF0983_01552	1.476e-06	61.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,3VPBR@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
SRR25158456_k127_2047970_1	1121920.AUAU01000012_gene2670	3.853e-77	267.0	COG0663@1|root,COG0663@2|Bacteria	2|Bacteria	G	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158456_k127_2047970_3	693986.MOC_4620	1.377e-55	201.0	COG0412@1|root,COG0412@2|Bacteria,1R6AF@1224|Proteobacteria,2U0YG@28211|Alphaproteobacteria,1JUW3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158456_k127_2047970_10	1088721.NSU_0091	3.679e-05	52.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,2K8S9@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158456_k127_2047970_0	671143.DAMO_1933	0.0	1296.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158456_k127_2047970_6	1341155.FSS13T_21650	8.647e-27	123.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1HZGV@117743|Flavobacteriia,2NSS9@237|Flavobacterium	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158456_k127_2047970_7	1303518.CCALI_01175	1.573e-21	103.0	COG0607@1|root,32YCZ@2|Bacteria	2|Bacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
SRR25158456_k127_2047970_5	926566.Terro_2606	1.338e-27	117.0	COG0640@1|root,COG0640@2|Bacteria,3Y5UV@57723|Acidobacteria,2JNP2@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158456_k127_2050522_0	471852.Tcur_4689	0.0	1197.0	COG0714@1|root,COG0714@2|Bacteria,2GNQ8@201174|Actinobacteria,4EFT2@85012|Streptosporangiales	201174|Actinobacteria	NT	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5,DUF3686
SRR25158456_k127_2050522_1	263358.VAB18032_05250	1.017e-198	638.0	COG2268@1|root,COG2268@2|Bacteria,2GKB2@201174|Actinobacteria,4D8F8@85008|Micromonosporales	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158456_k127_2050522_4	1144275.COCOR_04470	8.951e-19	98.0	2A865@1|root,30X71@2|Bacteria,1RE6C@1224|Proteobacteria,4384S@68525|delta/epsilon subdivisions,2X3EU@28221|Deltaproteobacteria,2YVRE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2050522_2	1121413.JMKT01000015_gene314	2.326e-73	273.0	COG2202@1|root,COG3920@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3920@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MAT9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,SBP_bac_3,sCache_2
SRR25158456_k127_2050522_3	1223523.H340_13716	2.574e-36	160.0	COG4447@1|root,COG4447@2|Bacteria,2IGT5@201174|Actinobacteria	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2051939_13	1343740.M271_35755	2.102e-49	200.0	2DP7T@1|root,330W7@2|Bacteria,2IH3C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2051939_19	886377.Murru_1105	2.484e-20	107.0	2AEU9@1|root,314RJ@2|Bacteria,4PJ0A@976|Bacteroidetes,1IB5C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2051939_27	509191.AEDB02000003_gene1019	0.0002405	44.0	2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia,3WQ8C@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2051939_17	547559.Nmag_0542	7.145e-24	106.0	arCOG02435@1|root,arCOG02435@2157|Archaea,2XX22@28890|Euryarchaeota,23VIS@183963|Halobacteria	183963|Halobacteria	F	Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
SRR25158456_k127_2051939_5	443143.GM18_0137	1.005e-164	534.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158456_k127_2051939_28	1267534.KB906755_gene3946	0.0004623	46.0	COG2952@1|root,COG2952@2|Bacteria,3Y55F@57723|Acidobacteria,2JJNJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF507)	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
SRR25158456_k127_2051939_1	323848.Nmul_A2189	1.245e-269	856.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,3720I@32003|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158456_k127_2051939_0	1232410.KI421422_gene2032	1.207e-286	902.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158456_k127_2051939_14	316067.Geob_0003	1.659e-46	181.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,42SYJ@68525|delta/epsilon subdivisions,2WP80@28221|Deltaproteobacteria,43T4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158456_k127_2051939_9	234267.Acid_0002	6.541e-85	294.0	COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria	57723|Acidobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158456_k127_2051939_6	204669.Acid345_0001	6.723e-133	438.0	COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria,2JHN7@204432|Acidobacteriia	204432|Acidobacteriia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158456_k127_2051939_23	644966.Tmar_2374	1.76e-12	69.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158456_k127_2051939_24	309803.CTN_1030	1.889e-10	68.0	COG0594@1|root,COG0594@2|Bacteria,2GDAX@200918|Thermotogae	200918|Thermotogae	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158456_k127_2051939_15	373994.Riv7116_6462	4.342e-26	115.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1HPBQ@1161|Nostocales	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158456_k127_2051939_10	1047013.AQSP01000133_gene2153	6.295e-82	293.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158456_k127_2051939_22	411470.RUMGNA_00877	2.666e-16	90.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3XZCW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158456_k127_2051939_7	1267533.KB906734_gene4408	1.078e-93	324.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria,2JHNN@204432|Acidobacteriia	204432|Acidobacteriia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
SRR25158456_k127_2051939_4	756272.Plabr_3360	3.764e-184	597.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
SRR25158456_k127_2051939_20	1265505.ATUG01000003_gene315	1.591e-17	90.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2WPKF@28221|Deltaproteobacteria,2MJSC@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158456_k127_2051939_8	518766.Rmar_0452	6.956e-93	311.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1FJ0J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Cellulose biosynthesis protein BcsQ	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158456_k127_2051939_12	1410631.JHWZ01000012_gene2052	6.251e-69	245.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,27IWA@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158456_k127_2051939_16	1499967.BAYZ01000105_gene3530	5.336e-25	109.0	COG1664@1|root,COG1664@2|Bacteria,2NQ1N@2323|unclassified Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
SRR25158456_k127_2051939_21	243231.GSU1638	1.87e-17	90.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,43UMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SRR25158456_k127_2051939_26	1122611.KB903996_gene7574	6.316e-05	52.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4EIJW@85012|Streptosporangiales	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158456_k127_2051939_25	1121918.ARWE01000001_gene3516	8.844e-08	64.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,43SQ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATP synthase B/B' CF(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158456_k127_2051939_18	1198114.AciX9_1152	1.459e-20	98.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria,2JJM8@204432|Acidobacteriia	204432|Acidobacteriia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158456_k127_2051939_2	671143.DAMO_2962	7.579e-228	715.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSB619.SA_RS10975	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158456_k127_2051939_11	234267.Acid_0464	2.439e-79	274.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158456_k127_2051939_3	1267535.KB906767_gene3118	2.625e-202	637.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158456_k127_2055839_2	1242864.D187_004426	4.36e-06	52.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,PD40,Peptidase_C14,WD40
SRR25158456_k127_2055839_1	1347369.CCAD010000076_gene3344	1.433e-61	235.0	COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,4HCF8@91061|Bacilli,1ZQGC@1386|Bacillus	91061|Bacilli	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158456_k127_2055839_0	1120971.AUCA01000032_gene3042	2.172e-138	457.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,2784J@186823|Alicyclobacillaceae	91061|Bacilli	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158456_k127_20565_5	1217705.F900_01055	5.222e-19	97.0	2DYV8@1|root,32V63@2|Bacteria,1QNWV@1224|Proteobacteria,1ST2X@1236|Gammaproteobacteria,3NNP1@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_20565_13	1246448.ANAZ01000001_gene4079	1.04e-06	62.0	COG5434@1|root,COG5434@2|Bacteria,2I4GP@201174|Actinobacteria	201174|Actinobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
SRR25158456_k127_20565_4	498848.TaqDRAFT_4792	2.377e-27	127.0	COG3299@1|root,COG3299@2|Bacteria,1WKVC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Baseplate J family protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
SRR25158456_k127_20565_14	926554.KI912617_gene4721	4.8e-06	58.0	2DX78@1|root,343PU@2|Bacteria,1WN2J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_20565_16	1120917.AQXM01000062_gene1961	0.0001884	54.0	COG5412@1|root,COG5412@2|Bacteria,2H75F@201174|Actinobacteria,1WAGF@1268|Micrococcaceae	201174|Actinobacteria	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_20565_3	526227.Mesil_1920	1.909e-35	153.0	28I3G@1|root,2Z7IH@2|Bacteria,1WJVT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF2586)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_20565_17	498848.TaqDRAFT_5482	0.0009779	51.0	28I3G@1|root,2Z7IH@2|Bacteria,1WM0N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF2586)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2586
SRR25158456_k127_20565_11	925775.XVE_1207	1.471e-08	68.0	COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria,1X3TK@135614|Xanthomonadales	135614|Xanthomonadales	OU	Belongs to the peptidase S14 family	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease,Mu-like_gpT
SRR25158456_k127_20565_1	498848.TaqDRAFT_4774	7.66e-46	186.0	COG2369@1|root,COG2369@2|Bacteria,1WMJJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
SRR25158456_k127_20565_0	498848.TaqDRAFT_4773	7.42e-60	228.0	COG4383@1|root,COG4383@2|Bacteria	2|Bacteria	L	Mu-like prophage protein gp29	-	-	-	-	-	-	-	-	-	-	-	-	DUF935
SRR25158456_k127_20565_2	1489678.RDMS_01640	1.725e-44	179.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
SRR25158456_k127_2058117_5	452637.Oter_0829	7.795e-08	61.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_2058117_2	448385.sce7280	6.272e-61	236.0	2DB7W@1|root,2Z7P1@2|Bacteria,1N65F@1224|Proteobacteria,434RW@68525|delta/epsilon subdivisions,2X8ZY@28221|Deltaproteobacteria,2Z17U@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158456_k127_2058117_3	562970.Btus_0876	1.333e-51	193.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,4I47R@91061|Bacilli,279PC@186823|Alicyclobacillaceae	91061|Bacilli	P	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158456_k127_2058117_4	903818.KI912268_gene2839	7.297e-35	144.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158456_k127_2058117_1	880073.Calab_3349	1.674e-143	474.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_3349|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2058117_0	1444712.BN1013_02223	8.937e-151	487.0	COG1960@1|root,COG1960@2|Bacteria,2JFSS@204428|Chlamydiae	204428|Chlamydiae	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158456_k127_2061572_2	1268072.PSAB_08670	7.451e-39	162.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,26T15@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRR25158456_k127_2061572_3	880072.Desac_1962	2.085e-26	126.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CF9@68525|delta/epsilon subdivisions,2X7QB@28221|Deltaproteobacteria,2MS55@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K16087,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.2,1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_2061572_1	1379270.AUXF01000002_gene1393	9.467e-49	180.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SRR25158456_k127_2061572_0	608538.HTH_0112	1.178e-50	186.0	COG5009@1|root,COG5009@2|Bacteria,2G3MT@200783|Aquificae	200783|Aquificae	M	Penicillin-binding protein 1A	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158456_k127_2071914_1	204669.Acid345_1042	4.614e-17	84.0	COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria,2JIVZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158456_k127_2071914_0	316274.Haur_3896	2.101e-50	190.0	COG0614@1|root,COG0614@2|Bacteria,2G8ZP@200795|Chloroflexi,375F3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
SRR25158456_k127_2071914_2	1120934.KB894405_gene5372	2.079e-08	67.0	COG1361@1|root,COG1361@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3344
SRR25158456_k127_2085584_4	391937.NA2_15127	1.963e-05	47.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TSRC@28211|Alphaproteobacteria,43HX0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158456_k127_2085584_1	644966.Tmar_1461	5.283e-91	309.0	COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,24J4X@186801|Clostridia	186801|Clostridia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158456_k127_2085584_2	1121403.AUCV01000018_gene3198	1.286e-68	248.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2MKXA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
SRR25158456_k127_2085584_3	1118235.CAJH01000001_gene13	1.371e-33	139.0	COG0494@1|root,COG0494@2|Bacteria,1RI3B@1224|Proteobacteria,1S6HR@1236|Gammaproteobacteria,1X4QN@135614|Xanthomonadales	135614|Xanthomonadales	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158456_k127_2085584_0	266117.Rxyl_3138	6.712e-135	439.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158456_k127_2090470_2	269799.Gmet_1777	1e-68	239.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158456_k127_2090470_5	1237149.C900_02647	6.809e-33	141.0	2CD06@1|root,33116@2|Bacteria,4NUTM@976|Bacteroidetes,47SJU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158456_k127_2090470_3	290397.Adeh_2885	2.531e-50	181.0	COG0346@1|root,COG0346@2|Bacteria,1MZD3@1224|Proteobacteria,434M2@68525|delta/epsilon subdivisions,2X8XQ@28221|Deltaproteobacteria,2Z0XI@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158456_k127_2090470_0	338963.Pcar_1712	8.078e-289	905.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,43S35@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	E1-E2 ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SRR25158456_k127_2090470_1	203119.Cthe_0686	3.12e-119	425.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158456_k127_2090470_4	1111479.AXAR01000003_gene1736	1.471e-39	168.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,279W3@186823|Alicyclobacillaceae	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158456_k127_2108909_0	1163407.UU7_12466	5.654e-37	151.0	COG1075@1|root,COG1075@2|Bacteria,1P9JY@1224|Proteobacteria,1RYH4@1236|Gammaproteobacteria,1X4KM@135614|Xanthomonadales	135614|Xanthomonadales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2108909_1	1121373.KB903620_gene1969	6.403e-13	72.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47JI8@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
SRR25158456_k127_210936_0	247634.GPB2148_1949	9.175e-133	432.0	COG1032@1|root,COG1032@2|Bacteria,1RECP@1224|Proteobacteria,1SPEE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158456_k127_210936_3	1223521.BBJX01000009_gene1208	1.405e-53	190.0	COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,2VSIB@28216|Betaproteobacteria,4AECV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158456_k127_210936_2	357808.RoseRS_1720	3.751e-91	310.0	COG0438@1|root,COG0438@2|Bacteria,2GA65@200795|Chloroflexi,376N7@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158456_k127_210936_1	756272.Plabr_0480	2.328e-129	423.0	COG1089@1|root,COG1089@2|Bacteria,2IWZ4@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158456_k127_210936_5	935840.JAEQ01000015_gene3751	5.192e-08	65.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,43HW5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158456_k127_210936_4	404589.Anae109_2378	1.949e-19	103.0	COG0642@1|root,COG2205@2|Bacteria	404589.Anae109_2378|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2109916_4	292415.Tbd_2758	5.599e-47	181.0	COG0500@1|root,COG2226@2|Bacteria,1MVXG@1224|Proteobacteria,2VM9F@28216|Betaproteobacteria,1KT70@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158456_k127_2109916_1	1396418.BATQ01000116_gene4615	4.644e-173	560.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
SRR25158456_k127_2109916_0	1191523.MROS_1137	3.72e-191	627.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158456_k127_2109916_5	1121012.AUKX01000014_gene2728	0.000394	51.0	2CG1Y@1|root,31NHZ@2|Bacteria,4NQ9Z@976|Bacteroidetes,1I375@117743|Flavobacteriia,23HBG@178469|Arenibacter	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
SRR25158456_k127_2109916_3	215803.DB30_6950	2.026e-80	284.0	COG1538@1|root,COG1538@2|Bacteria,1PTZ6@1224|Proteobacteria,42RK2@68525|delta/epsilon subdivisions,2X282@28221|Deltaproteobacteria,2YV1K@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158456_k127_2109916_2	215803.DB30_6949	4.705e-108	379.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WN4R@28221|Deltaproteobacteria,2YVY4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_2115726_1	504487.JCM19302_745	3.141e-10	66.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158456_k127_2115726_0	234267.Acid_0956	2.735e-48	181.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria	57723|Acidobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158456_k127_2116559_4	3218.PP1S40_57V6.1	1.758e-17	87.0	COG0167@1|root,KOG1799@2759|Eukaryota,37JTE@33090|Viridiplantae,3GDIQ@35493|Streptophyta	35493|Streptophyta	F	dihydropyrimidine dehydrogenase	-	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016627,GO:0016628,GO:0016651,GO:0017113,GO:0017144,GO:0019860,GO:0031667,GO:0031668,GO:0031669,GO:0034641,GO:0042737,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0055086,GO:0055114,GO:0071496,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.3.1.2	ko:K00207	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00978,R01415,R08226	RC00072,RC00123,RC02245	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158456_k127_2116559_3	713586.KB900536_gene2460	3.088e-49	191.0	COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,1S2VU@1236|Gammaproteobacteria,1WYNS@135613|Chromatiales	135613|Chromatiales	J	pteridine-dependent deoxygenase	-	-	4.1.3.40,4.1.3.45	ko:K18240	ko00130,ko00400,ko01100,ko01110,map00130,map00400,map01100,map01110	M00117	R01302,R10597	RC00491,RC02148,RC03212	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158456_k127_2116559_1	290397.Adeh_3515	2.028e-76	287.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,42P68@68525|delta/epsilon subdivisions,2WMKD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158456_k127_2116559_0	215803.DB30_5624	5.188e-213	669.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42PXH@68525|delta/epsilon subdivisions,2WKEX@28221|Deltaproteobacteria,2YTWX@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158456_k127_2116559_6	1122179.KB890417_gene3237	4.289e-08	63.0	COG3710@1|root,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158456_k127_2116559_5	197221.22295064	9.807e-09	65.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
SRR25158456_k127_2116559_2	204669.Acid345_2716	4.595e-63	241.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_2127228_1	215803.DB30_1696	3.441e-213	672.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,42ZYH@68525|delta/epsilon subdivisions,2WVEZ@28221|Deltaproteobacteria,2YZS1@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CBM_20,DUF3459
SRR25158456_k127_2127228_4	1242864.D187_001103	8.716e-157	502.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria,2YUG1@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.20	ko:K05816,ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
SRR25158456_k127_2127228_3	215803.DB30_1694	1.243e-169	542.0	COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,43EXV@68525|delta/epsilon subdivisions,2X9AJ@28221|Deltaproteobacteria,2YZDJ@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10108,ko:K15770	ko02010,ko02030,map02010,map02030	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	SBP_bac_1
SRR25158456_k127_2127228_2	378806.STAUR_7140	3.425e-187	604.0	COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,42UM4@68525|delta/epsilon subdivisions,2WQPJ@28221|Deltaproteobacteria,2YUAR@29|Myxococcales	28221|Deltaproteobacteria	P	Sugar ABC transporter permease	malF	-	-	ko:K10109,ko:K15770,ko:K15771	ko02010,map02010	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	BPD_transp_1,SBP_bac_8
SRR25158456_k127_2127228_5	215803.DB30_1692	1.607e-138	448.0	COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,42R4X@68525|delta/epsilon subdivisions,2WN1E@28221|Deltaproteobacteria,2YU8W@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10110,ko:K15772	ko02010,map02010	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	BPD_transp_1
SRR25158456_k127_2127228_6	215803.DB30_1691	1.095e-104	347.0	COG4945@1|root,COG4945@2|Bacteria,1NQHX@1224|Proteobacteria,439DS@68525|delta/epsilon subdivisions,2X4NP@28221|Deltaproteobacteria,2YZBB@29|Myxococcales	28221|Deltaproteobacteria	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C
SRR25158456_k127_2127228_0	215803.DB30_1690	5.286e-262	826.0	2CB5G@1|root,33TBA@2|Bacteria,1NS5Z@1224|Proteobacteria,439KD@68525|delta/epsilon subdivisions,2X4X3@28221|Deltaproteobacteria,2YZSA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2127228_7	215803.DB30_1689	3.518e-56	207.0	COG4945@1|root,COG4945@2|Bacteria,1NYP6@1224|Proteobacteria,4394H@68525|delta/epsilon subdivisions,2X4AK@28221|Deltaproteobacteria,2YYMF@29|Myxococcales	28221|Deltaproteobacteria	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C
SRR25158456_k127_2127228_8	1517416.IDAT_04120	1.668e-07	57.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Tox-GHH,WHH
SRR25158456_k127_2133074_0	861299.J421_2862	1.555e-73	258.0	COG0499@1|root,COG0499@2|Bacteria,1ZTEF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158456_k127_2133074_1	1121918.ARWE01000001_gene2006	2.948e-49	189.0	COG0330@1|root,COG0330@2|Bacteria,1R8RD@1224|Proteobacteria,42QFB@68525|delta/epsilon subdivisions,2WJQE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158456_k127_2133074_2	1304885.AUEY01000017_gene3766	1.197e-44	185.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2WK2W@28221|Deltaproteobacteria,2MMS8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158456_k127_2137457_0	234267.Acid_7763	2.855e-111	379.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria	57723|Acidobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158456_k127_2137457_2	903818.KI912268_gene762	1.744e-35	145.0	COG0664@1|root,COG1716@1|root,COG0664@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,cNMP_binding
SRR25158456_k127_2137457_1	1117958.PE143B_0100605	5.065e-59	216.0	COG1619@1|root,COG1619@2|Bacteria,1RDGY@1224|Proteobacteria,1T05T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	peptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158456_k127_2137457_3	1268303.RHODMAR_2721	4.276e-12	71.0	2AR1Y@1|root,31GAW@2|Bacteria,2HK0E@201174|Actinobacteria,4G7PU@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2137457_4	246196.MSMEI_3387	1.046e-05	53.0	COG3688@1|root,COG3688@2|Bacteria,2HS1T@201174|Actinobacteria,23A4M@1762|Mycobacteriaceae	201174|Actinobacteria	S	YacP-like NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158456_k127_2138407_4	1282360.ABAC460_05370	0.000141	54.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2TSY5@28211|Alphaproteobacteria,2KKA1@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158456_k127_2138407_2	1120999.JONM01000012_gene2242	3.128e-21	109.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG2373@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG2373@2|Bacteria,COG4733@2|Bacteria,1QV7E@1224|Proteobacteria,2WHIN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM Outer membrane protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
SRR25158456_k127_2138407_0	861299.J421_4062	3.788e-57	229.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158456_k127_2138407_1	748658.KB907314_gene100	2.505e-39	158.0	2DBXQ@1|root,2ZBQY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
SRR25158456_k127_2138407_3	1123257.AUFV01000020_gene2085	3.359e-05	47.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,1RS16@1236|Gammaproteobacteria,1X4TS@135614|Xanthomonadales	135614|Xanthomonadales	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158456_k127_2141113_1	794903.OPIT5_22915	1.062e-07	57.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA,VWA_3
SRR25158456_k127_2141113_0	794903.OPIT5_22920	7.104e-137	451.0	COG3829@1|root,COG3829@2|Bacteria,46Z7D@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
SRR25158456_k127_2141609_0	697284.ERIC2_c02660	2.174e-175	571.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,26R57@186822|Paenibacillaceae	91061|Bacilli	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SRR25158456_k127_2141609_4	1123511.KB905841_gene1348	1.625e-07	62.0	2ASQ0@1|root,31I4U@2|Bacteria,1VZD6@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2141609_2	498761.HM1_2362	7.344e-52	199.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia	186801|Clostridia	KT	stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	MASE3,PAS_4,PAS_9,SpoIIE
SRR25158456_k127_2141609_3	235909.GK0046	1.047e-51	192.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1WF6P@129337|Geobacillus	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158456_k127_2141609_1	1519464.HY22_13955	1.312e-166	566.0	COG1239@1|root,COG1239@2|Bacteria,1FF03@1090|Chlorobi	1090|Chlorobi	H	Sigma-54 interaction domain	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Sigma54_activat
SRR25158456_k127_2144685_16	204669.Acid345_2146	4.867e-32	143.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
SRR25158456_k127_2144685_6	1278073.MYSTI_04859	3.349e-84	285.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2YVHT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
SRR25158456_k127_2144685_9	349521.HCH_04045	4.698e-67	237.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1XS7F@135619|Oceanospirillales	135619|Oceanospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158456_k127_2144685_1	1347086.CCBA010000024_gene3041	1.755e-127	439.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus	91061|Bacilli	S	ABC transporter	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158456_k127_2144685_5	204669.Acid345_2140	8.209e-86	300.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria,2JHTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158456_k127_2144685_19	743299.Acife_1535	1.772e-16	84.0	COG1487@1|root,COG1487@2|Bacteria,1QG6Z@1224|Proteobacteria,1SFI1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_2144685_8	1382359.JIAL01000001_gene2620	3.909e-80	283.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria,2JI1B@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158456_k127_2144685_3	667014.Thein_2089	2.023e-116	387.0	COG0743@1|root,COG0743@2|Bacteria,2GHA5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158456_k127_2144685_14	1499967.BAYZ01000078_gene990	1.576e-48	184.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
SRR25158456_k127_2144685_7	1121468.AUBR01000029_gene1582	1.114e-81	280.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158456_k127_2144685_12	401526.TcarDRAFT_1028	2.763e-52	196.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4H2Z4@909932|Negativicutes	909932|Negativicutes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158456_k127_2144685_20	204669.Acid345_0913	1.849e-16	93.0	COG2304@1|root,COG2304@2|Bacteria,3Y98A@57723|Acidobacteria,2JP4V@204432|Acidobacteriia	204432|Acidobacteriia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2144685_10	56780.SYN_00169	1.343e-63	231.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2MQD5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158456_k127_2144685_18	1499967.BAYZ01000103_gene3780	4.217e-23	116.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000103_gene3780|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2144685_17	1193729.A1OE_1168	1.83e-23	116.0	COG1216@1|root,COG1216@2|Bacteria,1R6SJ@1224|Proteobacteria,2U47V@28211|Alphaproteobacteria,2JZFD@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2144685_13	287986.DV20_08880	7.585e-50	192.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4DXK5@85010|Pseudonocardiales	201174|Actinobacteria	M	glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
SRR25158456_k127_2144685_15	1379698.RBG1_1C00001G0386	9.262e-45	177.0	COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158456_k127_2144685_11	234267.Acid_7442	2.668e-63	242.0	COG1216@1|root,COG1216@2|Bacteria,3Y7CJ@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2144685_4	234267.Acid_7443	1.236e-89	314.0	COG0438@1|root,COG0438@2|Bacteria,3Y6A8@57723|Acidobacteria	57723|Acidobacteria	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_trans_1_4
SRR25158456_k127_2144685_2	247490.KSU1_C1600	7.047e-118	395.0	COG2148@1|root,COG2148@2|Bacteria,2IYWX@203682|Planctomycetes	203682|Planctomycetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158456_k127_2144685_0	379066.GAU_3087	9.567e-144	466.0	COG0076@1|root,COG0076@2|Bacteria,1ZSZN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158456_k127_2144722_3	215803.DB30_3013	2.473e-26	115.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SRR25158456_k127_2144722_0	1379698.RBG1_1C00001G1265	9.583e-136	446.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_2144722_2	1145276.T479_08760	1.902e-28	132.0	COG1524@1|root,COG1524@2|Bacteria,1VI7B@1239|Firmicutes,4IQDY@91061|Bacilli	91061|Bacilli	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158456_k127_2144722_1	234267.Acid_5235	7.307e-97	327.0	COG0402@1|root,COG0402@2|Bacteria,3Y64N@57723|Acidobacteria	57723|Acidobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158456_k127_214529_0	215803.DB30_6830	2.602e-122	395.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YYIW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158456_k127_214529_2	938289.CAJN020000003_gene910	2.783e-30	133.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,2686P@186813|unclassified Clostridiales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158456_k127_214529_1	926550.CLDAP_25100	5.446e-85	286.0	COG0221@1|root,COG0221@2|Bacteria,2G6T4@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158456_k127_2157794_2	222984.JNCS01000001_gene1924	5.263e-06	60.0	arCOG08113@1|root,arCOG08113@2157|Archaea,2XV1B@28890|Euryarchaeota,23TAX@183963|Halobacteria	183963|Halobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158456_k127_2157794_1	316067.Geob_1583	1.137e-19	105.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_2157794_0	1117318.PRUB_18812	1.715e-69	253.0	COG3209@1|root,COG3209@2|Bacteria,1Q6K4@1224|Proteobacteria,1RVWZ@1236|Gammaproteobacteria,2Q57T@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2186431_7	62928.azo0383	1.429e-40	157.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,2KZNP@206389|Rhodocyclales	206389|Rhodocyclales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_2186431_8	290397.Adeh_4019	9.011e-33	140.0	COG2050@1|root,COG2050@2|Bacteria,1RKGI@1224|Proteobacteria,42WI1@68525|delta/epsilon subdivisions,2WSAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
SRR25158456_k127_2186431_3	1267534.KB906754_gene3465	4.643e-107	354.0	COG0491@1|root,COG0491@2|Bacteria,3Y54H@57723|Acidobacteria,2JM9F@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_2186431_13	655815.ZPR_0794	3.122e-06	55.0	2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,1I3WH@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2186431_5	1125863.JAFN01000001_gene3329	3.497e-52	201.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRR25158456_k127_2186431_0	1242864.D187_004919	3.416e-166	529.0	COG0174@1|root,COG0174@2|Bacteria,1NZU7@1224|Proteobacteria	1224|Proteobacteria	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158456_k127_2186431_2	1499967.BAYZ01000028_gene1281	4.076e-113	383.0	COG0747@1|root,COG0747@2|Bacteria,2NR54@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158456_k127_2186431_1	1267535.KB906767_gene5241	3.621e-123	421.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158456_k127_2186431_9	525257.HMPREF0204_10811	1.659e-25	110.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I2SV@117743|Flavobacteriia,3ZS3U@59732|Chryseobacterium	976|Bacteroidetes	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158456_k127_2186431_6	945713.IALB_2247	1.856e-49	191.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
SRR25158456_k127_2186431_4	315730.BcerKBAB4_2079	1.365e-54	212.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,1ZBVX@1386|Bacillus	91061|Bacilli	E	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction	dat	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158456_k127_2186431_10	1408254.T458_10525	7.071e-18	87.0	COG3324@1|root,COG3324@2|Bacteria,1VC83@1239|Firmicutes,4HKUE@91061|Bacilli,26ZN9@186822|Paenibacillaceae	91061|Bacilli	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158456_k127_2186431_11	1286093.C266_17941	1.276e-10	67.0	COG0457@1|root,COG0457@2|Bacteria	1286093.C266_17941|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2190372_1	1304275.C41B8_18181	8.717e-174	559.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,1SYJH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_7
SRR25158456_k127_2190372_0	525909.Afer_1020	0.0	1470.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CNGZ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158456_k127_2190372_2	1123228.AUIH01000008_gene2400	6.31e-83	296.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,STAS_2,Sulfate_transp
SRR25158456_k127_2193212_2	1384054.N790_02960	1.549e-70	261.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158456_k127_2193212_1	1384054.N790_02955	1.179e-97	331.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158456_k127_2193212_3	1384054.N790_02950	2.922e-53	208.0	COG5485@1|root,COG5485@2|Bacteria,1RDG8@1224|Proteobacteria,1S4CM@1236|Gammaproteobacteria,1X71J@135614|Xanthomonadales	135614|Xanthomonadales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158456_k127_2193212_0	573370.DMR_38040	3.378e-205	666.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_2194217_10	58123.JOFJ01000019_gene3879	2.41e-17	83.0	COG5516@1|root,COG5516@2|Bacteria,2ID3R@201174|Actinobacteria,4EK5G@85012|Streptosporangiales	201174|Actinobacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158456_k127_2194217_8	1297742.A176_03509	3.275e-63	231.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,438D4@68525|delta/epsilon subdivisions,2X3NA@28221|Deltaproteobacteria,2YWMP@29|Myxococcales	28221|Deltaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158456_k127_2194217_5	448385.sce2665	1.711e-81	276.0	COG1335@1|root,COG1335@2|Bacteria,1MZP9@1224|Proteobacteria,42SNF@68525|delta/epsilon subdivisions,2X6IF@28221|Deltaproteobacteria,2Z22A@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158456_k127_2194217_7	864051.BurJ1DRAFT_4049	4.762e-67	251.0	COG3391@1|root,COG3391@2|Bacteria,1NFEK@1224|Proteobacteria,2W53Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2194217_6	234267.Acid_5241	9.379e-70	243.0	COG1262@1|root,COG1262@2|Bacteria	234267.Acid_5241|-	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2194217_3	240015.ACP_3138	5.242e-122	400.0	COG3384@1|root,COG3384@2|Bacteria,3Y57M@57723|Acidobacteria	57723|Acidobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158456_k127_2194217_0	523791.Kkor_2389	5.504e-154	507.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1XP2X@135619|Oceanospirillales	135619|Oceanospirillales	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158456_k127_2194217_2	1382359.JIAL01000001_gene2460	8.35e-136	447.0	COG1680@1|root,COG1680@2|Bacteria,3Y3DY@57723|Acidobacteria,2JHVC@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_2194217_1	63737.Npun_F4742	2.062e-151	488.0	COG0667@1|root,COG0667@2|Bacteria,1G2QT@1117|Cyanobacteria,1HRA6@1161|Nostocales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158456_k127_2194217_4	378806.STAUR_4566	1.822e-112	371.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QY0@68525|delta/epsilon subdivisions,2WMTP@28221|Deltaproteobacteria,2YWVG@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158456_k127_2194217_9	696281.Desru_1117	2.197e-61	227.0	COG0438@1|root,COG0500@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG2226@2|Bacteria,1V06G@1239|Firmicutes,247WU@186801|Clostridia	186801|Clostridia	H	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_23
SRR25158456_k127_2215134_0	56107.Cylst_6183	6.651e-183	589.0	COG3733@1|root,COG3733@2|Bacteria,1G2YB@1117|Cyanobacteria,1HMBG@1161|Nostocales	1117|Cyanobacteria	Q	PFAM Copper amine oxidase, N2 domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRR25158456_k127_2215134_1	861299.J421_1756	1.227e-158	514.0	COG0624@1|root,COG0624@2|Bacteria,1ZUA4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158456_k127_2215134_3	1192034.CAP_1140	3.723e-12	76.0	2A835@1|root,30X3P@2|Bacteria,1QB0X@1224|Proteobacteria,435DE@68525|delta/epsilon subdivisions,2WZR0@28221|Deltaproteobacteria,2Z2JH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2215134_2	1185876.BN8_03867	6.302e-93	317.0	COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,47KS4@768503|Cytophagia	976|Bacteroidetes	V	peptidase U61 LD-carboxypeptidase A	ldcA	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158456_k127_2215309_9	357808.RoseRS_1386	1.874e-10	69.0	2FI0A@1|root,349T8@2|Bacteria,2G93A@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2215309_7	66897.DJ64_12145	2.623e-11	76.0	COG2013@1|root,COG2013@2|Bacteria,2GNEK@201174|Actinobacteria	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR25158456_k127_2215309_5	378806.STAUR_5400	7.879e-17	94.0	COG0457@1|root,COG2013@1|root,COG0457@2|Bacteria,COG2013@2|Bacteria,1P3IM@1224|Proteobacteria,431ZR@68525|delta/epsilon subdivisions,2WWC2@28221|Deltaproteobacteria,2YVCM@29|Myxococcales	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,TPR_16,TPR_19,TPR_8
SRR25158456_k127_2215309_3	338963.Pcar_1321	6.186e-37	153.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,43SJX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4124)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
SRR25158456_k127_2215309_2	760568.Desku_1707	1.051e-38	148.0	COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,24KA0@186801|Clostridia,2621J@186807|Peptococcaceae	186801|Clostridia	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158456_k127_2215309_8	1121904.ARBP01000002_gene6731	9.656e-11	67.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
SRR25158456_k127_2215309_10	1122604.JONR01000037_gene4238	2.93e-05	53.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,1X51A@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2215309_1	443143.GM18_0868	6.73e-91	307.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158456_k127_2215309_0	1069080.KB913028_gene1442	2.649e-167	542.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4H2T2@909932|Negativicutes	909932|Negativicutes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158456_k127_2215309_4	204669.Acid345_0720	1.761e-17	85.0	COG3027@1|root,COG3027@2|Bacteria,3Y5IJ@57723|Acidobacteria,2JJZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
SRR25158456_k127_2215309_6	926566.Terro_1682	1.722e-12	79.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria,2JJBA@204432|Acidobacteriia	204432|Acidobacteriia	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
SRR25158456_k127_2219795_2	118168.MC7420_536	2.924e-07	63.0	COG0265@1|root,COG1672@1|root,COG0265@2|Bacteria,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria,1H73P@1150|Oscillatoriales	1117|Cyanobacteria	KLT	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,TIR_2,Trypsin_2
SRR25158456_k127_2219795_0	215803.DB30_0358	3.133e-16	93.0	COG0823@1|root,COG1520@1|root,COG3055@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Ig_3,PD40,PKD,Peptidase_S8
SRR25158456_k127_2219795_1	1144275.COCOR_03629	9.344e-10	66.0	2EH77@1|root,33AZ1@2|Bacteria,1NMNZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2256515_19	378806.STAUR_0492	1.278e-37	146.0	2E4AE@1|root,32Z64@2|Bacteria,1NE9W@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2256515_10	518766.Rmar_2758	3.855e-68	258.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3852@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3852@2|Bacteria,4NDXU@976|Bacteroidetes,1FJVE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158456_k127_2256515_1	1125863.JAFN01000001_gene1060	1.999e-101	347.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_2256515_14	107635.AZUO01000001_gene2095	1.453e-58	216.0	COG0463@1|root,COG0463@2|Bacteria,1R6A0@1224|Proteobacteria,2TVNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2256515_6	648757.Rvan_3115	4.024e-88	305.0	COG0438@1|root,COG0438@2|Bacteria,1MWEM@1224|Proteobacteria,2U1NW@28211|Alphaproteobacteria,3N8RC@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_2256515_15	314345.SPV1_00477	2.301e-55	219.0	2B8B9@1|root,33Q4Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2256515_12	1147.D082_21610	2.42e-63	232.0	COG1216@1|root,COG1216@2|Bacteria,1G0HY@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158456_k127_2256515_11	1187851.A33M_3020	7.187e-65	246.0	COG0438@1|root,COG0438@2|Bacteria,1RF49@1224|Proteobacteria,2U7J6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_2256515_20	941449.dsx2_1572	8.724e-32	136.0	COG0500@1|root,COG2226@2|Bacteria,1N73D@1224|Proteobacteria,42XDU@68525|delta/epsilon subdivisions,2WTBP@28221|Deltaproteobacteria,2MBEV@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158456_k127_2256515_22	1142394.PSMK_13650	4.227e-24	115.0	COG1216@1|root,COG1216@2|Bacteria,2J16E@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2256515_5	314345.SPV1_07451	2.584e-89	318.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.11	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3	-	Glycogen_syn,Glycos_transf_1
SRR25158456_k127_2256515_17	314345.SPV1_07456	1.542e-51	203.0	COG1215@1|root,COG1215@2|Bacteria,1QVAX@1224|Proteobacteria	1224|Proteobacteria	M	Pfam Glycosyl transferase family 2	-	-	2.4.1.122	ko:K21366	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
SRR25158456_k127_2256515_3	314345.SPV1_07461	7.232e-94	317.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158456_k127_2256515_16	489825.LYNGBM3L_52710	2.483e-53	196.0	COG2518@1|root,COG2518@2|Bacteria,1GR78@1117|Cyanobacteria,1HE58@1150|Oscillatoriales	1117|Cyanobacteria	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
SRR25158456_k127_2256515_8	1496688.ER33_03635	2.393e-82	285.0	COG1216@1|root,COG1216@2|Bacteria,1GIVG@1117|Cyanobacteria,22THI@167375|Cyanobium	1117|Cyanobacteria	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158456_k127_2256515_18	1279009.ADICEAN_01126	8.938e-48	193.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NTP_transf_5
SRR25158456_k127_2256515_13	313606.M23134_04362	1.699e-61	231.0	COG4122@1|root,COG4122@2|Bacteria,4NP2A@976|Bacteroidetes,47SZD@768503|Cytophagia	976|Bacteroidetes	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
SRR25158456_k127_2256515_24	316275.VSAL_I3015	2.673e-07	63.0	2AX1D@1|root,31NZK@2|Bacteria,1QKNS@1224|Proteobacteria,1TIT8@1236|Gammaproteobacteria,1XZKY@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2256515_21	272134.KB731324_gene1690	2.899e-31	132.0	COG1215@1|root,COG1215@2|Bacteria,1G7KN@1117|Cyanobacteria	1117|Cyanobacteria	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158456_k127_2256515_7	107635.AZUO01000001_gene2086	7.727e-86	292.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2U57D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	transport, permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158456_k127_2256515_4	41431.PCC8801_3355	2.628e-92	333.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,3KHG3@43988|Cyanothece	1117|Cyanobacteria	GM	PFAM ABC transporter related	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158456_k127_2256515_2	596151.DesfrDRAFT_2348	1.913e-96	345.0	COG0451@1|root,COG0451@2|Bacteria,1PBJP@1224|Proteobacteria,43AUZ@68525|delta/epsilon subdivisions,2X692@28221|Deltaproteobacteria,2MADF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158456_k127_2256515_0	1121456.ATVA01000017_gene96	1.085e-153	494.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,42NV5@68525|delta/epsilon subdivisions,2WU5T@28221|Deltaproteobacteria,2M95B@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158456_k127_2256515_9	1496688.ER33_03655	2.069e-74	275.0	COG1216@1|root,COG1216@2|Bacteria,1GHQX@1117|Cyanobacteria,22T9B@167375|Cyanobium	1117|Cyanobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2256515_23	1123504.JQKD01000002_gene3621	2.385e-11	64.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2VHJ2@28216|Betaproteobacteria,4ABD2@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM acyltransferase 3	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158456_k127_2264594_1	1121028.ARQE01000005_gene2844	3.068e-21	99.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_7,Response_reg
SRR25158456_k127_2264594_0	1121920.AUAU01000002_gene2134	1.564e-96	328.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158456_k127_2264594_2	1250278.JQNQ01000001_gene3430	7.8e-20	99.0	COG0526@1|root,COG0526@2|Bacteria,4NNV9@976|Bacteroidetes,1IIRD@117743|Flavobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158456_k127_2268742_3	335543.Sfum_1456	4.808e-92	328.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MQ56@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
SRR25158456_k127_2268742_0	335543.Sfum_1457	0.0	1220.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158456_k127_2268742_2	335543.Sfum_1458	1.798e-98	333.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_2268742_8	246197.MXAN_2711	5.729e-15	83.0	COG1309@1|root,COG1309@2|Bacteria,1NQ0S@1224|Proteobacteria,43AGR@68525|delta/epsilon subdivisions,2WN8X@28221|Deltaproteobacteria,2YX94@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRR25158456_k127_2268742_1	1121920.AUAU01000019_gene2584	1.629e-213	692.0	COG2936@1|root,COG2936@2|Bacteria,3Y33N@57723|Acidobacteria	57723|Acidobacteria	S	Hydrolase CocE NonD family	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SRR25158456_k127_2268742_4	404589.Anae109_2307	3.336e-80	282.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria	1224|Proteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158456_k127_2268742_6	1089544.KB912942_gene3115	1.431e-36	142.0	COG3742@1|root,COG3742@2|Bacteria,2IS39@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158456_k127_2268742_7	300852.55771884	9.077e-17	83.0	COG4423@1|root,COG4423@2|Bacteria,1WKIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Rv0623-like transcription factor	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	PSK_trans_fac
SRR25158456_k127_2268742_5	56110.Oscil6304_1395	1.883e-43	166.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_2270241_5	105420.BBPO01000059_gene3239	3.086e-10	66.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158456_k127_2270241_2	471853.Bcav_1963	1.064e-25	112.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158456_k127_2270241_3	1100721.ALKO01000032_gene173	3.76e-21	96.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,2VXUM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158456_k127_2270241_6	340177.Cag_1751	0.0001525	47.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	yefM	-	2.3.1.15	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	-	-	-	PhdYeFM_antitox
SRR25158456_k127_2270241_0	204669.Acid345_3346	6.01e-45	172.0	2E0G4@1|root,32W27@2|Bacteria	2|Bacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
SRR25158456_k127_2270241_1	794903.OPIT5_10185	4.553e-26	114.0	COG2402@1|root,COG2402@2|Bacteria,46ZMF@74201|Verrucomicrobia,3K9YW@414999|Opitutae	414999|Opitutae	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2270241_4	118161.KB235922_gene4921	5.159e-21	96.0	COG0023@1|root,COG0023@2|Bacteria,1G6P3@1117|Cyanobacteria,3VK5K@52604|Pleurocapsales	1117|Cyanobacteria	J	PFAM translation initiation factor SUI1	sui1	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SRR25158456_k127_2284383_8	311403.Arad_3660	1.418e-22	111.0	COG0558@1|root,COG0558@2|Bacteria,1RHFC@1224|Proteobacteria,2UACA@28211|Alphaproteobacteria,4B80S@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	cdp-diacylglycerol--glycerol-3-phosphate	pgsAb	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
SRR25158456_k127_2284383_9	1185876.BN8_01690	7.02e-22	99.0	COG2913@1|root,COG2913@2|Bacteria,4NYPJ@976|Bacteroidetes,47WT5@768503|Cytophagia	976|Bacteroidetes	J	Protein of unknown function (DUF3574)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3574
SRR25158456_k127_2284383_10	215803.DB30_7610	4.581e-09	70.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158456_k127_2284383_0	1267533.KB906738_gene2247	7.264e-174	595.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria,2JI4Z@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
SRR25158456_k127_2284383_13	102107.XP_008222422.1	2.188e-06	57.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37MB0@33090|Viridiplantae,3GFCB@35493|Streptophyta,4JKX4@91835|fabids	35493|Streptophyta	O	metalloendoproteinase 1-like	-	-	3.4.24.34	ko:K01402,ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
SRR25158456_k127_2284383_15	4513.MLOC_5946.3	6.47e-05	52.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37MGX@33090|Viridiplantae,3GE77@35493|Streptophyta,3KXPR@4447|Liliopsida,3I9GB@38820|Poales	35493|Streptophyta	O	Belongs to the peptidase M10A family	-	GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241	-	ko:K07761,ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
SRR25158456_k127_2284383_12	404589.Anae109_1265	4.548e-07	59.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2284383_4	44060.JODL01000004_gene2530	4.051e-75	267.0	COG0425@1|root,COG0425@2|Bacteria,2I4E3@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2284383_2	1254432.SCE1572_07880	1.47e-96	325.0	COG3221@1|root,COG3221@2|Bacteria,1N92V@1224|Proteobacteria,42TXU@68525|delta/epsilon subdivisions,2X5QC@28221|Deltaproteobacteria,2Z36U@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
SRR25158456_k127_2284383_3	196490.AUEZ01000006_gene5691	1.336e-84	312.0	COG1960@1|root,COG1960@2|Bacteria,1R9RG@1224|Proteobacteria,2TVS6@28211|Alphaproteobacteria,3JXZP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158456_k127_2284383_5	926549.KI421517_gene3913	1.253e-70	267.0	COG5012@1|root,COG5012@2|Bacteria,4NRCW@976|Bacteroidetes,47UR1@768503|Cytophagia	976|Bacteroidetes	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158456_k127_2284383_6	1307759.JOMJ01000003_gene1217	2.494e-62	229.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Y5I@68525|delta/epsilon subdivisions,2WUGI@28221|Deltaproteobacteria,2MEJ5@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_2284383_7	234267.Acid_4496	2.564e-31	128.0	COG2318@1|root,COG2318@2|Bacteria,3Y8UQ@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158456_k127_2284383_11	1209072.ALBT01000025_gene3716	3.359e-08	64.0	2EBMP@1|root,338FN@2|Bacteria,1R3GD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2284383_1	1562701.BBOF01000068_gene2200	4.781e-102	348.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,1K773@119060|Burkholderiaceae	28216|Betaproteobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
SRR25158456_k127_2291926_7	102125.Xen7305DRAFT_00047730	2.944e-19	97.0	COG1357@1|root,COG5635@1|root,COG1357@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,NACHT
SRR25158456_k127_2291926_2	1123360.thalar_00122	2.629e-64	239.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,2TSDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158456_k127_2291926_8	1502724.FF80_00324	4.221e-19	94.0	2C1VT@1|root,33ZY8@2|Bacteria	2|Bacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
SRR25158456_k127_2291926_1	439235.Dalk_4323	9.095e-111	376.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,42T8R@68525|delta/epsilon subdivisions,2WPR7@28221|Deltaproteobacteria,2MMKM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Strictosidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Str_synth
SRR25158456_k127_2291926_6	1211115.ALIQ01000076_gene3905	5.969e-27	114.0	COG3801@1|root,COG3801@2|Bacteria,1RGZ3@1224|Proteobacteria,2U95Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158456_k127_2291926_3	290397.Adeh_2967	4.805e-58	209.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2291926_10	1267535.KB906767_gene688	8.6e-09	61.0	2EVWN@1|root,33PAB@2|Bacteria,3Y5UR@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2291926_4	234267.Acid_2646	8.217e-50	205.0	COG2834@1|root,COG2834@2|Bacteria,3Y7NW@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2291926_0	234267.Acid_2647	0.0	1329.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,3Y6ZR@57723|Acidobacteria	57723|Acidobacteria	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_2291926_5	1041159.AZUW01000018_gene783	2.853e-27	124.0	2DM0H@1|root,316A1@2|Bacteria,1N0X9@1224|Proteobacteria,2UEZ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2296706_3	861299.J421_0373	1.286e-119	392.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	3.2.1.15	ko:K01184	ko00040,ko01100,map00040,map01100	M00081	R01982,R02360	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_28,Glyco_hydro_88,Pectate_lyase_3
SRR25158456_k127_2296706_4	234267.Acid_2736	1.047e-98	344.0	COG3718@1|root,COG3718@2|Bacteria	2|Bacteria	G	enzyme involved in inositol metabolism	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158456_k127_2296706_2	1254432.SCE1572_31455	4.059e-170	541.0	COG0524@1|root,COG0524@2|Bacteria,1QNWF@1224|Proteobacteria,430AW@68525|delta/epsilon subdivisions,2WW4X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158456_k127_2296706_9	682795.AciX8_3658	9.84e-68	239.0	COG0800@1|root,COG0800@2|Bacteria,3Y4HZ@57723|Acidobacteria,2JKJ9@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158456_k127_2296706_8	1123242.JH636434_gene5235	2.36e-72	279.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
SRR25158456_k127_2296706_15	1032480.MLP_36660	4.152e-48	192.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	AurF,Fer4_19,Ferritin-like,zf-CDGSH
SRR25158456_k127_2296706_19	1254432.SCE1572_12045	3.401e-34	153.0	2EQU0@1|root,33IDQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2296706_13	861299.J421_1627	2.737e-51	186.0	COG1720@1|root,COG1720@2|Bacteria	2|Bacteria	S	tRNA m6t6A37 methyltransferase activity	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158456_k127_2296706_21	1122214.AQWH01000011_gene2170	5.315e-33	142.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TSWP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lysine exporter protein (LysE YggA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158456_k127_2296706_20	1128421.JAGA01000003_gene3091	5.03e-33	148.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_2296706_6	1300345.LF41_2280	7.11e-85	289.0	COG2810@1|root,COG2810@2|Bacteria,1RFCH@1224|Proteobacteria	1224|Proteobacteria	V	stress, protein	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2,TerD
SRR25158456_k127_2296706_16	913325.N799_09925	3.864e-42	162.0	COG2810@1|root,COG2810@2|Bacteria,1RFCH@1224|Proteobacteria	1224|Proteobacteria	V	stress, protein	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2,TerD
SRR25158456_k127_2296706_25	1408444.JHYC01000009_gene1668	1.99e-22	111.0	COG1807@1|root,COG1807@2|Bacteria,1QC7N@1224|Proteobacteria,1T7WU@1236|Gammaproteobacteria,1JFYQ@118969|Legionellales	118969|Legionellales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2296706_7	1313172.YM304_12760	4.17e-77	287.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
SRR25158456_k127_2296706_5	349521.HCH_05016	1.086e-97	346.0	COG3447@1|root,COG5001@1|root,COG3447@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XHII@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,MASE1
SRR25158456_k127_2296706_1	1121920.AUAU01000001_gene2279	0.0	1253.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_2296706_27	504728.K649_06980	0.0001884	47.0	COG5573@1|root,COG5573@2|Bacteria	2|Bacteria	K	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_2296706_28	237368.SCABRO_03923	0.0007783	46.0	COG2002@1|root,COG2002@2|Bacteria,2J3S7@203682|Planctomycetes	203682|Planctomycetes	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158456_k127_2296706_26	78245.Xaut_3745	0.0001533	51.0	2DMHT@1|root,32RN3@2|Bacteria,1N0KK@1224|Proteobacteria,2UCFK@28211|Alphaproteobacteria,3F1RC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	-	-	MA20_36130	-	-	-	-	-	-	-	-	-	-	-	PEGA
SRR25158456_k127_2296706_10	1148.1652394	4.237e-63	228.0	COG1028@1|root,COG1028@2|Bacteria,1GEZW@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158456_k127_2296706_17	1192034.CAP_5243	9.446e-42	155.0	COG0640@1|root,COG0640@2|Bacteria,1N10H@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158456_k127_2296706_18	1205680.CAKO01000040_gene1090	4.356e-40	158.0	COG3832@1|root,COG3832@2|Bacteria,1RJJY@1224|Proteobacteria,2U9FZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_2296706_23	667632.KB890187_gene3067	4.511e-23	109.0	COG3009@1|root,COG3009@2|Bacteria,1NPN2@1224|Proteobacteria,2W7SY@28216|Betaproteobacteria,1K63S@119060|Burkholderiaceae	28216|Betaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
SRR25158456_k127_2296706_11	765911.Thivi_0028	3.188e-59	233.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1WWQS@135613|Chromatiales	135613|Chromatiales	Q	PFAM Mammalian cell entry related	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
SRR25158456_k127_2296706_14	1038869.AXAN01000011_gene6661	8.535e-50	195.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2VMXT@28216|Betaproteobacteria,1K5RP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
SRR25158456_k127_2296706_24	28072.Nos7524_4685	1.052e-22	101.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_2296706_22	357808.RoseRS_4060	8.286e-29	135.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_2296706_0	1519464.HY22_12075	0.0	1292.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_2296706_12	661478.OP10G_1985	7.592e-55	201.0	COG0745@1|root,COG0745@2|Bacteria	661478.OP10G_1985|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2301339_0	1121920.AUAU01000007_gene408	6.17e-108	369.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158456_k127_2301339_7	1047013.AQSP01000099_gene1496	1.897e-13	76.0	COG1826@1|root,COG1826@2|Bacteria,2NQ3N@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.A.64,2.C.1.2	-	-	MttA_Hcf106
SRR25158456_k127_2301339_3	1047013.AQSP01000099_gene1495	1.087e-68	242.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158456_k127_2301339_5	234267.Acid_1212	9.614e-36	148.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03770,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158456_k127_2301339_1	338966.Ppro_2189	6.7e-106	373.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,43TQ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM aminotransferase, class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_2301339_2	1379698.RBG1_1C00001G0361	2.978e-104	352.0	COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158456_k127_2301339_6	1121468.AUBR01000015_gene2266	4.742e-26	125.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,42GJG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158456_k127_2301339_4	1267535.KB906767_gene4492	5.107e-65	240.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria,2JIGR@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158456_k127_2302439_1	290397.Adeh_4303	2.043e-40	161.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,43DY0@68525|delta/epsilon subdivisions,2X918@28221|Deltaproteobacteria,2Z1ER@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158456_k127_2302439_0	1125863.JAFN01000001_gene2041	6.598e-85	300.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158456_k127_2302439_2	1262449.CP6013_0761	3.951e-05	53.0	29VIW@1|root,30H17@2|Bacteria,1UGZJ@1239|Firmicutes,25PM0@186801|Clostridia,36RZ0@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2308086_7	1125971.ASJB01000065_gene6209	2.027e-42	166.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria,4E37G@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginase family	argI	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158456_k127_2308086_5	935863.AWZR01000012_gene2538	3.561e-56	208.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158456_k127_2308086_8	66869.JNXG01000013_gene6744	8.982e-42	164.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,417GB@629295|Streptomyces griseus group	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR25158456_k127_2308086_4	1384054.N790_02955	7.966e-58	215.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158456_k127_2308086_6	1144275.COCOR_02285	4.643e-55	215.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	response regulator	yehT	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158456_k127_2308086_2	404589.Anae109_0474	3.734e-80	277.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158456_k127_2308086_9	1267535.KB906767_gene784	3.991e-29	123.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_2308086_1	448385.sce7823	1.153e-100	340.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42R0K@68525|delta/epsilon subdivisions,2WMTU@28221|Deltaproteobacteria,2Z309@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158456_k127_2308086_3	246197.MXAN_2607	5.094e-76	274.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTWP@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158456_k127_2308086_0	1242864.D187_009322	2.498e-136	447.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2X9B9@28221|Deltaproteobacteria,2YX2A@29|Myxococcales	28221|Deltaproteobacteria	P	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158456_k127_23183_2	1379270.AUXF01000005_gene351	1.063e-97	324.0	COG1228@1|root,COG1228@2|Bacteria,1ZSME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158456_k127_23183_1	1123368.AUIS01000001_gene1853	8.375e-113	371.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,1SM99@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_23183_3	1150600.ADIARSV_3000	1.443e-95	339.0	COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1IQR7@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158456_k127_23183_7	163908.KB235896_gene984	2.261e-19	96.0	COG0457@1|root,COG0457@2|Bacteria,1G649@1117|Cyanobacteria,1HM2D@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
SRR25158456_k127_23183_4	419610.Mext_2279	1.453e-37	162.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,1JSJI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SRR25158456_k127_23183_6	627192.SLG_30670	7.328e-23	114.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2K12C@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_23183_5	526225.Gobs_2511	9.896e-35	142.0	COG0398@1|root,COG0398@2|Bacteria,2GYCV@201174|Actinobacteria	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158456_k127_23183_0	497964.CfE428DRAFT_2129	2.033e-275	863.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158456_k127_2319736_3	1123368.AUIS01000044_gene15	7.36e-131	430.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,2ND0X@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158456_k127_2319736_14	584708.Apau_1828	3.924e-17	87.0	COG4637@1|root,COG4637@2|Bacteria,3TCHW@508458|Synergistetes	508458|Synergistetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2319736_9	584708.Apau_1828	6.171e-27	118.0	COG4637@1|root,COG4637@2|Bacteria,3TCHW@508458|Synergistetes	508458|Synergistetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2319736_1	204669.Acid345_2811	2.912e-186	604.0	COG0362@1|root,COG0362@2|Bacteria,3Y990@57723|Acidobacteria,2JP1Q@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158456_k127_2319736_0	204669.Acid345_2810	2.14e-301	950.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,3Y5VJ@57723|Acidobacteria,2JKZ5@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglucose isomerase	-	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158456_k127_2319736_5	251229.Chro_3079	1.311e-85	297.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,3VJ5H@52604|Pleurocapsales	1117|Cyanobacteria	S	TIGRFAM YihY family protein (not ribonuclease BN)	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158456_k127_2319736_4	1487953.JMKF01000053_gene1741	4.687e-98	327.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria,1G3D1@1117|Cyanobacteria,1H7UZ@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158456_k127_2319736_8	1379270.AUXF01000001_gene2616	1.368e-29	128.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,PAS,Response_reg,SBP_bac_3
SRR25158456_k127_2319736_6	1118235.CAJH01000054_gene3169	1.734e-69	249.0	COG0726@1|root,COG0726@2|Bacteria,1RFCG@1224|Proteobacteria,1S808@1236|Gammaproteobacteria,1X451@135614|Xanthomonadales	135614|Xanthomonadales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158456_k127_2319736_2	697303.Thewi_1417	9.157e-151	488.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,42FGH@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158456_k127_2319736_7	1121920.AUAU01000006_gene301	3.344e-36	158.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2319736_13	944479.JQLX01000015_gene135	4.713e-19	88.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2M7EP@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158456_k127_2319736_12	234267.Acid_2571	1.488e-21	95.0	COG1837@1|root,COG1837@2|Bacteria,3Y5N5@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158456_k127_2319736_11	411902.CLOBOL_03702	7.462e-23	106.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,220BW@1506553|Lachnoclostridium	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158456_k127_2319736_10	1268622.AVS7_00384	1.056e-24	106.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,4ABE9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158456_k127_2319822_12	218284.CCDN010000001_gene445	1.795e-20	107.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus	91061|Bacilli	M	cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,MucBP
SRR25158456_k127_2319822_13	391624.OIHEL45_02990	6.313e-13	75.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2,DUF4437
SRR25158456_k127_2319822_3	1395571.TMS3_0107090	1.349e-100	340.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	sumf2	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158456_k127_2319822_8	215803.DB30_2740	9.545e-64	240.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria,2YVDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Iron/manganese superoxide dismutases, C-terminal domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158456_k127_2319822_7	1267535.KB906767_gene1462	1.068e-78	275.0	COG1131@1|root,COG1131@2|Bacteria,3Y7J3@57723|Acidobacteria,2JMS8@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2319822_10	1267535.KB906767_gene1461	5.059e-35	153.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K19341	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158456_k127_2319822_11	1242864.D187_006184	1.266e-34	144.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,4376W@68525|delta/epsilon subdivisions,2X277@28221|Deltaproteobacteria,2Z1SB@29|Myxococcales	28221|Deltaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
SRR25158456_k127_2319822_9	1267534.KB906756_gene390	2.924e-63	229.0	COG4947@1|root,COG4947@2|Bacteria,3Y4B1@57723|Acidobacteria,2JKYT@204432|Acidobacteriia	204432|Acidobacteriia	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158456_k127_2319822_2	926566.Terro_2080	1.752e-105	351.0	COG0189@1|root,COG0189@2|Bacteria,3Y37D@57723|Acidobacteria,2JI05@204432|Acidobacteriia	204432|Acidobacteriia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2319822_0	1123276.KB893268_gene4992	2.145e-156	503.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158456_k127_2319822_14	525373.HMPREF0766_14255	5.886e-06	59.0	COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1IPYJ@117747|Sphingobacteriia	976|Bacteroidetes	F	GMP synthase-glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRR25158456_k127_2319822_4	861299.J421_4352	5.917e-96	326.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158456_k127_2319822_5	767817.Desgi_4305	7.086e-87	304.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,25ZYM@186807|Peptococcaceae	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158456_k127_2319822_1	1232410.KI421422_gene2064	4.474e-137	449.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,43RXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158456_k127_2319822_15	478741.JAFS01000002_gene266	2.071e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,46YVP@74201|Verrucomicrobia,37G32@326457|unclassified Verrucomicrobia	478741.JAFS01000002_gene266|-	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2319822_6	269799.Gmet_0961	2.286e-82	286.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_2324512_1	562970.Btus_0655	8.331e-94	321.0	COG1522@1|root,COG1522@2|Bacteria,1V6TH@1239|Firmicutes,4HAAQ@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator (AsnC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
SRR25158456_k127_2324512_6	215803.DB30_3268	9.321e-16	82.0	COG1547@1|root,COG1547@2|Bacteria,1P75K@1224|Proteobacteria,432ZJ@68525|delta/epsilon subdivisions,2WXIJ@28221|Deltaproteobacteria,2Z233@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158456_k127_2324512_0	1267533.KB906735_gene4826	3.47e-132	430.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158456_k127_2324512_3	706587.Desti_1483	1.747e-32	140.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phosphotransferase related to Ser Thr protein kinases	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158456_k127_2324512_2	436308.Nmar_1740	2.557e-42	179.0	COG0652@1|root,arCOG04767@2157|Archaea,41T32@651137|Thaumarchaeota	651137|Thaumarchaeota	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158456_k127_2324512_7	33876.JNXY01000004_gene1408	3.593e-07	63.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4DDXR@85008|Micromonosporales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158456_k127_2324512_8	234267.Acid_4093	0.0002461	53.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158456_k127_2324512_5	1121422.AUMW01000024_gene240	1.543e-29	125.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_2324512_4	1047013.AQSP01000138_gene1046	2.492e-31	137.0	COG3307@1|root,COG3307@2|Bacteria,2NQ25@2323|unclassified Bacteria	2|Bacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
SRR25158456_k127_2324692_1	404589.Anae109_3071	1.06e-252	803.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,42PE5@68525|delta/epsilon subdivisions,2WK7C@28221|Deltaproteobacteria,2YU9Z@29|Myxococcales	28221|Deltaproteobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158456_k127_2324692_0	479434.Sthe_1092	0.0	1357.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158456_k127_2334221_6	338963.Pcar_1692	2.269e-23	115.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43RXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158456_k127_2334221_3	269799.Gmet_2318	9.682e-58	209.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,43U3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158456_k127_2334221_4	1121033.AUCF01000009_gene1087	4.377e-36	149.0	COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria,2UFTW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2334221_2	888062.HMPREF9083_0352	1.308e-58	213.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158456_k127_2334221_0	477974.Daud_1572	1.916e-269	856.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24BRX@186801|Clostridia,260H8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158456_k127_2334221_1	696281.Desru_1280	7.052e-97	321.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,260V1@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158456_k127_2334221_8	1415756.JQMY01000001_gene3422	2.556e-05	56.0	COG3391@1|root,COG3391@2|Bacteria,1MXJJ@1224|Proteobacteria,2TTH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,NHL
SRR25158456_k127_2334221_7	562743.JH976438_gene2046	3.398e-21	97.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR25158456_k127_2334221_5	234267.Acid_2439	2.785e-31	129.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158456_k127_2334309_2	518766.Rmar_2600	1.377e-88	300.0	COG0412@1|root,COG0412@2|Bacteria,4NE8V@976|Bacteroidetes,1FJNW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158456_k127_2334309_0	543728.Vapar_1657	2.479e-170	548.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2VIKV@28216|Betaproteobacteria,4AESP@80864|Comamonadaceae	28216|Betaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158456_k127_2334309_1	290397.Adeh_2943	9.102e-124	424.0	COG0784@1|root,COG3437@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_2334309_3	1123508.JH636441_gene3386	5.808e-13	80.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4347,MAM,Trypsin_2
SRR25158456_k127_2340789_1	243233.MCA1168	8.142e-88	327.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,1RS9J@1236|Gammaproteobacteria,1XFU5@135618|Methylococcales	135618|Methylococcales	H	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SRR25158456_k127_2340789_0	1123368.AUIS01000027_gene1355	1.269e-244	767.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,1RNN4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158456_k127_2340789_3	345073.VC395_1708	1.117e-25	123.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,1XYDA@135623|Vibrionales	135623|Vibrionales	T	EAL domain	-	-	3.1.4.52	ko:K20963	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL
SRR25158456_k127_2340789_4	358220.C380_05065	2.615e-13	80.0	COG0745@1|root,COG2197@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,2VH9E@28216|Betaproteobacteria,4AAGF@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_2340789_2	321327.CYA_2836	1.7e-52	195.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1GYFK@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_234328_6	1144275.COCOR_04801	6.167e-12	70.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158456_k127_234328_1	69395.JQLZ01000001_gene3113	2.11e-50	194.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2KFMD@204458|Caulobacterales	204458|Caulobacterales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_234328_3	1382303.JPOM01000001_gene1757	1.273e-30	129.0	COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,2U0I4@28211|Alphaproteobacteria,2KGB5@204458|Caulobacterales	204458|Caulobacterales	L	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158456_k127_234328_2	1192034.CAP_3318	6.157e-34	141.0	COG0314@1|root,COG0315@1|root,COG0314@2|Bacteria,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2WP2P@28221|Deltaproteobacteria,2YVDR@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158456_k127_234328_5	867845.KI911784_gene1282	7.621e-16	82.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77,2.8.1.12,4.6.1.17	ko:K03636,ko:K03637,ko:K03752,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372,R11581	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0736,iEC55989_1330.EC55989_0827,iG2583_1286.G2583_1012,iLF82_1304.LF82_1368,iNRG857_1313.NRG857_03495,iSFV_1184.SFV_0767,iSF_1195.SF0734,iSFxv_1172.SFxv_0800,iSSON_1240.SSON_0763,iS_1188.S0775	ThiS
SRR25158456_k127_234328_0	1123371.ATXH01000021_gene1117	5.878e-196	641.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GHDG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158456_k127_234328_4	350058.Mvan_3505	5.202e-19	90.0	COG2730@1|root,COG3469@1|root,COG2730@2|Bacteria,COG3469@2|Bacteria,2GJTU@201174|Actinobacteria,2384A@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	chiA2	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,CBM_4_9,Glyco_hydro_18,Ricin_B_lectin,fn3
SRR25158456_k127_2355600_3	391625.PPSIR1_30255	2.823e-12	81.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	Dam,PhageMin_Tail
SRR25158456_k127_2355600_2	391625.PPSIR1_30270	2.399e-12	82.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158456_k127_2355600_4	522306.CAP2UW1_0478	4.263e-06	55.0	2E8EM@1|root,332T0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2358003_15	1294273.roselon_01674	0.0001278	45.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
SRR25158456_k127_2358003_6	671143.DAMO_2702	5.918e-49	183.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158456_k127_2358003_13	903818.KI912268_gene3080	1.037e-11	72.0	COG0636@1|root,COG0636@2|Bacteria,3Y5G6@57723|Acidobacteria	57723|Acidobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158456_k127_2358003_11	1231241.Mc24_07643	2.055e-17	86.0	COG1725@1|root,COG1725@2|Bacteria,2GDGX@200918|Thermotogae	200918|Thermotogae	K	PFAM regulatory protein GntR HTH	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158456_k127_2358003_12	1437609.BCAL_0834	9.155e-14	83.0	COG4194@1|root,COG4194@2|Bacteria,2IBNS@201174|Actinobacteria,4CZJU@85004|Bifidobacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
SRR25158456_k127_2358003_9	935567.JAES01000024_gene1464	5.923e-40	158.0	COG2207@1|root,COG2207@2|Bacteria,1N70D@1224|Proteobacteria,1SCZK@1236|Gammaproteobacteria,1X94Q@135614|Xanthomonadales	135614|Xanthomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158456_k127_2358003_10	935261.JAGL01000003_gene3150	3.124e-26	116.0	2E4GK@1|root,32ZBS@2|Bacteria,1N72D@1224|Proteobacteria,2UGDA@28211|Alphaproteobacteria,43KNQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
SRR25158456_k127_2358003_3	926554.KI912671_gene402	9.346e-145	469.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR25158456_k127_2358003_2	861299.J421_1931	5.722e-183	583.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158456_k127_2358003_4	365046.Rta_13470	4.611e-135	456.0	COG0492@1|root,COG0664@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,1MVX2@1224|Proteobacteria,2VM3V@28216|Betaproteobacteria,4AHC9@80864|Comamonadaceae	28216|Betaproteobacteria	C	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,cNMP_binding
SRR25158456_k127_2358003_0	292459.STH2842	6.5e-234	733.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia	186801|Clostridia	E	Beta-eliminating lyase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158456_k127_2358003_7	1218352.B597_018715	8.388e-49	190.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RR5A@1236|Gammaproteobacteria,1Z4HI@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	ko:K02613,ko:K07140,ko:K21832	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,FA_desaturase,Fer2,NAD_binding_1
SRR25158456_k127_2358003_8	945713.IALB_0798	5.306e-40	160.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
SRR25158456_k127_2358003_5	694427.Palpr_0869	2.126e-93	346.0	COG0484@1|root,COG0484@2|Bacteria,4P0AH@976|Bacteroidetes,2FYI2@200643|Bacteroidia	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2358003_1	204669.Acid345_0471	8.785e-186	626.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2362408_0	391587.KAOT1_04255	0.0	1833.0	COG3321@1|root,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3321 Polyketide synthase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase,DUF2156,ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_2364714_1	13690.CP98_02547	1.408e-183	592.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2K16Q@204457|Sphingomonadales	204457|Sphingomonadales	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158456_k127_2364714_8	1345697.M493_16915	5.778e-06	59.0	COG5652@1|root,COG5652@2|Bacteria,1TU2J@1239|Firmicutes,4HQ9P@91061|Bacilli,1WGH9@129337|Geobacillus	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158456_k127_2364714_5	472759.Nhal_1223	3.264e-62	239.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1WXGP@135613|Chromatiales	135613|Chromatiales	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K01079,ko:K07315	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	GAF,HAMP,SpoIIE,dCache_1
SRR25158456_k127_2364714_0	388051.AUFE01000049_gene3933	7.088e-233	736.0	2DBN3@1|root,2ZA1Q@2|Bacteria,1NRYG@1224|Proteobacteria,2W1E2@28216|Betaproteobacteria,1KDEY@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2364714_3	388051.AUFE01000049_gene3932	8.896e-130	424.0	COG1633@1|root,COG1633@2|Bacteria,1QW2P@1224|Proteobacteria,2WH0T@28216|Betaproteobacteria,1KIGH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Ferritin-like	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin-like
SRR25158456_k127_2364714_2	269797.Mbar_A0545	2.504e-163	559.0	COG2319@1|root,arCOG02561@2157|Archaea	2157|Archaea	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,WD40
SRR25158456_k127_2364714_7	3055.EDO99838	1.403e-14	89.0	KOG0272@1|root,KOG0272@2759|Eukaryota,37HYM@33090|Viridiplantae,34JFC@3041|Chlorophyta	3041|Chlorophyta	A	pre-mRNA processing factor 4 (PRP4) like	-	-	-	ko:K12662	ko03040,map03040	M00354	-	-	ko00000,ko00001,ko00002,ko03041	-	-	-	PRP4,WD40
SRR25158456_k127_2364714_6	593750.Metfor_0576	5.717e-50	190.0	arCOG08211@1|root,arCOG08211@2157|Archaea,2XW85@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2364714_4	521098.Aaci_0705	5.554e-115	385.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,4HB28@91061|Bacilli	91061|Bacilli	IQ	dehydrogenase	yuxG	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158456_k127_2381924_6	204669.Acid345_2692	1.945e-22	112.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2381924_7	204669.Acid345_0034	3.183e-19	90.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria,2JJW0@204432|Acidobacteriia	204432|Acidobacteriia	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158456_k127_2381924_9	1121430.JMLG01000003_gene651	5.75e-09	67.0	2DQUD@1|root,338R2@2|Bacteria,1VXI6@1239|Firmicutes,251UZ@186801|Clostridia,265H2@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2381924_11	1198114.AciX9_3489	1.129e-05	53.0	2EA3B@1|root,3348D@2|Bacteria,3Y5J1@57723|Acidobacteria,2JJZE@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2381924_5	398525.KB900701_gene2301	1.75e-24	118.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,2TUYH@28211|Alphaproteobacteria,3JSAB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2381924_10	471854.Dfer_1127	2.895e-08	66.0	COG3595@1|root,COG3595@2|Bacteria,4NJBA@976|Bacteroidetes,47MRP@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2381924_12	330214.NIDE1012	0.0001162	50.0	COG1714@1|root,COG1714@2|Bacteria,3J0U3@40117|Nitrospirae	40117|Nitrospirae	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158456_k127_2381924_3	111105.HR09_10025	8.577e-38	149.0	COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,2FQHX@200643|Bacteroidia,22WR7@171551|Porphyromonadaceae	976|Bacteroidetes	S	YigZ family	yigZ	-	-	-	-	-	-	-	-	-	-	-	UPF0029
SRR25158456_k127_2381924_2	304371.MCP_0033	5.431e-43	173.0	COG2094@1|root,arCOG04295@2157|Archaea,2Y0AE@28890|Euryarchaeota,2NB07@224756|Methanomicrobia	224756|Methanomicrobia	L	alkylbase DNA N-glycosylase activity	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158456_k127_2381924_0	1387312.BAUS01000011_gene1928	9.27e-65	254.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KKRI@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158456_k127_2381924_4	382464.ABSI01000012_gene2139	4.355e-28	133.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,VPEP
SRR25158456_k127_2381924_8	1237149.C900_02976	6.411e-11	76.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4P1A1@976|Bacteroidetes	976|Bacteroidetes	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2381924_1	871585.BDGL_001435	7.222e-52	201.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,3NKP6@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
SRR25158456_k127_2381924_13	290397.Adeh_3797	0.0001844	55.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_3797|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2389956_0	404589.Anae109_1040	8.792e-178	583.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SRR25158456_k127_2389956_1	404589.Anae109_4174	2.09e-23	106.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
SRR25158456_k127_2391889_1	1380393.JHVP01000007_gene4488	6.492e-202	656.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
SRR25158456_k127_2391889_0	1380393.JHVP01000007_gene4488	7.407e-208	670.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
SRR25158456_k127_2391889_2	1121861.KB899930_gene199	2.584e-135	439.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,2JPRD@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158456_k127_2391889_3	1382304.JNIL01000001_gene1094	4.226e-99	330.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158456_k127_2402149_3	1125863.JAFN01000001_gene1661	3.581e-51	188.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158456_k127_2402149_0	1499967.BAYZ01000095_gene4092	3e-190	614.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	Cytidylate_kin,LYTB,S1
SRR25158456_k127_2402149_2	1382359.JIAL01000001_gene2813	5.208e-66	240.0	COG0616@1|root,COG0616@2|Bacteria,3Y3M1@57723|Acidobacteria,2JI8A@204432|Acidobacteriia	204432|Acidobacteriia	OU	PFAM peptidase S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158456_k127_2402149_5	204669.Acid345_4105	2.72e-33	135.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158456_k127_2402149_4	234267.Acid_4300	5.403e-48	177.0	COG0537@1|root,COG0537@2|Bacteria,3Y4CN@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158456_k127_2402149_6	240015.ACP_0810	2.813e-12	76.0	2DTIS@1|root,33KJ1@2|Bacteria,3Y5U4@57723|Acidobacteria,2JN6V@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2402149_1	1144275.COCOR_02677	2.083e-71	251.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR25158456_k127_2409519_2	1499967.BAYZ01000084_gene3999	8.505e-88	299.0	COG1173@1|root,COG1173@2|Bacteria,2NQ14@2323|unclassified Bacteria	2|Bacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158456_k127_2409519_1	1499967.BAYZ01000076_gene838	2.236e-95	325.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158456_k127_2409519_3	1379698.RBG1_1C00001G1510	1.169e-67	261.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158456_k127_2409519_0	1379698.RBG1_1C00001G1511	2.252e-155	504.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158456_k127_2423169_2	497964.CfE428DRAFT_1495	6.768e-21	104.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158456_k127_2423169_0	497964.CfE428DRAFT_0942	1.005e-82	297.0	COG0644@1|root,COG0644@2|Bacteria,46SNH@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158456_k127_2423169_3	1237149.C900_02922	2.035e-19	90.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,47S6H@768503|Cytophagia	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158456_k127_2423169_5	614083.AWQR01000005_gene1044	3.467e-09	63.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,4ADIB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158456_k127_2423169_1	243231.GSU0460	4.037e-75	267.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,43TSR@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF-1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_2423169_4	1280668.ATVT01000019_gene1791	1.745e-16	91.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,4BXD3@830|Butyrivibrio	186801|Clostridia	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_2431283_7	215803.DB30_0881	2.096e-62	244.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1REF1@1224|Proteobacteria,42Q4N@68525|delta/epsilon subdivisions,2WS51@28221|Deltaproteobacteria,2YWNR@29|Myxococcales	28221|Deltaproteobacteria	O	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6,Peptidase_S8
SRR25158456_k127_2431283_13	1227499.C493_10035	0.0003378	54.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD,PQQ_2,PQQ_3
SRR25158456_k127_2431283_8	443143.GM18_3158	2.854e-39	161.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,437IE@68525|delta/epsilon subdivisions,2WVS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158456_k127_2431283_9	1379270.AUXF01000002_gene1799	1.597e-33	134.0	COG1846@1|root,COG1846@2|Bacteria,1ZU5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158456_k127_2431283_1	1297569.MESS2_770013	8.61e-163	531.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2TVBZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2431283_3	1005395.CSV86_07836	9.62e-94	324.0	COG1234@1|root,COG2333@1|root,COG1234@2|Bacteria,COG2333@2|Bacteria,1RBYH@1224|Proteobacteria	1224|Proteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_2431283_14	9361.ENSDNOP00000007395	0.0005051	54.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTVB@33213|Bilateria,4845F@7711|Chordata,48YFJ@7742|Vertebrata,3JEBN@40674|Mammalia	33208|Metazoa	T	lipoprotein receptor-related protein	LRP5	GO:0000902,GO:0001501,GO:0001503,GO:0001568,GO:0001649,GO:0001654,GO:0001667,GO:0001702,GO:0001745,GO:0001763,GO:0001932,GO:0001933,GO:0001944,GO:0002009,GO:0002053,GO:0002076,GO:0002165,GO:0002376,GO:0002520,GO:0002791,GO:0003002,GO:0003008,GO:0003013,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006355,GO:0006357,GO:0006469,GO:0006629,GO:0006915,GO:0006928,GO:0007088,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007346,GO:0007350,GO:0007365,GO:0007367,GO:0007369,GO:0007389,GO:0007399,GO:0007423,GO:0007444,GO:0007447,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008015,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008217,GO:0008219,GO:0008284,GO:0008587,GO:0009056,GO:0009653,GO:0009790,GO:0009791,GO:0009798,GO:0009826,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009952,GO:0009953,GO:0009966,GO:0009987,GO:0010464,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010817,GO:0010941,GO:0012501,GO:0015026,GO:0016020,GO:0016043,GO:0016049,GO:0016052,GO:0016055,GO:0016125,GO:0016477,GO:0017147,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019320,GO:0019827,GO:0022612,GO:0023051,GO:0023052,GO:0030111,GO:0030154,GO:0030278,GO:0030279,GO:0030326,GO:0030879,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032991,GO:0033043,GO:0033673,GO:0033688,GO:0033690,GO:0034103,GO:0035019,GO:0035107,GO:0035108,GO:0035113,GO:0035114,GO:0035120,GO:0035218,GO:0035220,GO:0035223,GO:0035239,GO:0035282,GO:0035295,GO:0035426,GO:0038023,GO:0040007,GO:0040011,GO:0042074,GO:0042127,GO:0042325,GO:0042326,GO:0042592,GO:0042632,GO:0042733,GO:0042813,GO:0042981,GO:0043010,GO:0043067,GO:0043086,GO:0043235,GO:0043549,GO:0044092,GO:0044093,GO:0044238,GO:0044281,GO:0044282,GO:0044332,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045600,GO:0045667,GO:0045668,GO:0045669,GO:0045778,GO:0045787,GO:0045840,GO:0045859,GO:0045893,GO:0045931,GO:0045935,GO:0045936,GO:0045944,GO:0046365,GO:0046849,GO:0046850,GO:0046883,GO:0048070,GO:0048073,GO:0048076,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048539,GO:0048563,GO:0048569,GO:0048583,GO:0048589,GO:0048592,GO:0048593,GO:0048598,GO:0048705,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048754,GO:0048771,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050708,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050796,GO:0050877,GO:0050890,GO:0050896,GO:0051046,GO:0051049,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051338,GO:0051348,GO:0051674,GO:0051716,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0055088,GO:0055092,GO:0060033,GO:0060041,GO:0060042,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060341,GO:0060348,GO:0060349,GO:0060429,GO:0060443,GO:0060444,GO:0060560,GO:0060561,GO:0060562,GO:0060603,GO:0060612,GO:0060764,GO:0060828,GO:0061138,GO:0061178,GO:0061180,GO:0061298,GO:0061299,GO:0061304,GO:0061448,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071936,GO:0071944,GO:0072358,GO:0072359,GO:0080090,GO:0090068,GO:0090087,GO:0090254,GO:0090276,GO:0090596,GO:0098727,GO:0098796,GO:0098797,GO:0198738,GO:1901360,GO:1901575,GO:1901615,GO:1902262,GO:1902652,GO:1902680,GO:1902742,GO:1903506,GO:1903508,GO:1903530,GO:1904928,GO:1905114,GO:1990851,GO:1990909,GO:2000112,GO:2001141	-	ko:K03068	ko04150,ko04310,ko05200,ko05224,ko05225,ko05226,map04150,map04310,map05200,map05224,map05225,map05226	-	-	-	ko00000,ko00001,ko04131	-	-	-	FXa_inhibition,Ldl_recept_a,Ldl_recept_b
SRR25158456_k127_2431283_4	1144275.COCOR_00106	1.721e-91	328.0	COG2355@1|root,COG2355@2|Bacteria,1MXA0@1224|Proteobacteria,437UQ@68525|delta/epsilon subdivisions,2X348@28221|Deltaproteobacteria,2YU6N@29|Myxococcales	28221|Deltaproteobacteria	E	Dickkopf N-terminal cysteine-rich region	-	-	-	-	-	-	-	-	-	-	-	-	Dickkopf_N,Peptidase_M19
SRR25158456_k127_2431283_12	1297742.A176_01405	1.396e-24	121.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,1NI1E@1224|Proteobacteria	1224|Proteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SRR25158456_k127_2431283_11	1268622.AVS7_00224	1.243e-26	117.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,4ADZP@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Thioredoxin domain	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158456_k127_2431283_10	1122611.KB903940_gene1754	4.368e-28	126.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4EFTZ@85012|Streptosporangiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158456_k127_2431283_6	765420.OSCT_0910	1.987e-62	239.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
SRR25158456_k127_2431283_2	1192034.CAP_5545	2.397e-118	395.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158456_k127_2431283_0	1254432.SCE1572_30430	1.027e-165	529.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X250@28221|Deltaproteobacteria,2YXZE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158456_k127_2441911_2	1121015.N789_07510	4.199e-104	350.0	COG0739@1|root,COG0739@2|Bacteria,1MXH6@1224|Proteobacteria,1SB0F@1236|Gammaproteobacteria,1X8J3@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158456_k127_2441911_0	204669.Acid345_2030	1.651e-176	574.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria,2JIC5@204432|Acidobacteriia	204432|Acidobacteriia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158456_k127_2441911_6	644283.Micau_2844	0.000695	46.0	2AGY4@1|root,3176Q@2|Bacteria,2HBIZ@201174|Actinobacteria,4DKB1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2441911_1	1150864.MILUP08_43218	3.759e-117	396.0	COG2242@1|root,COG2242@2|Bacteria,2IAR0@201174|Actinobacteria,4D9FM@85008|Micromonosporales	201174|Actinobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2441911_3	1219065.VPR01S_28_00330	7.649e-55	214.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
SRR25158456_k127_2441911_4	196162.Noca_2667	1.542e-42	180.0	COG0463@1|root,COG0463@2|Bacteria,2IPT1@201174|Actinobacteria,4DWY3@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase like family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158456_k127_2441911_5	404589.Anae109_1852	2.155e-23	112.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase,HATPase_c,HisKA,Response_reg
SRR25158456_k127_2443204_0	314230.DSM3645_19053	2.477e-130	430.0	COG0147@1|root,COG0147@2|Bacteria,2IX6Q@203682|Planctomycetes	203682|Planctomycetes	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158456_k127_2443204_7	1267534.KB906754_gene3649	3.275e-22	105.0	2AZDP@1|root,31RMA@2|Bacteria,3Y4JB@57723|Acidobacteria,2JJ76@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
SRR25158456_k127_2443204_2	479434.Sthe_1292	1.329e-111	368.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158456_k127_2443204_1	1192034.CAP_1695	4.234e-129	424.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_2443204_3	1379698.RBG1_1C00001G1285	1.305e-50	185.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158456_k127_2443204_5	204669.Acid345_2358	9.994e-37	151.0	COG0136@1|root,COG0136@2|Bacteria,3Y395@57723|Acidobacteria,2JI31@204432|Acidobacteriia	204432|Acidobacteriia	E	Semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158456_k127_2443204_4	1441629.PCH70_08290	2.204e-43	169.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1Z6J5@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158456_k127_2443204_8	123214.PERMA_0557	6.736e-08	56.0	299PZ@1|root,2ZWSA@2|Bacteria,2G5CR@200783|Aquificae	200783|Aquificae	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
SRR25158456_k127_2443204_6	1123392.AQWL01000003_gene322	3.166e-31	138.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,1KRDI@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_2443698_2	497964.CfE428DRAFT_5420	1.527e-29	128.0	2DM58@1|root,31S4C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2443698_1	497964.CfE428DRAFT_2106	2.047e-161	519.0	COG1522@1|root,COG1522@2|Bacteria,46SDK@74201|Verrucomicrobia	74201|Verrucomicrobia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2443698_0	649638.Trad_2519	0.0	1505.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1WIRD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158456_k127_2444171_6	1121897.AUGO01000011_gene3135	4.225e-35	142.0	28JH1@1|root,2Z9AM@2|Bacteria,4NJYJ@976|Bacteroidetes,1I0ZC@117743|Flavobacteriia,2NUWU@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2444171_1	765912.Thimo_1337	6.352e-209	685.0	COG2909@1|root,COG2909@2|Bacteria,1R4DB@1224|Proteobacteria,1THR3@1236|Gammaproteobacteria,1X0D9@135613|Chromatiales	135613|Chromatiales	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2444171_0	1242864.D187_007905	4.757e-220	693.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X3NE@28221|Deltaproteobacteria,2YWN3@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158456_k127_2444171_5	1499967.BAYZ01000076_gene778	8.532e-40	166.0	2EKYY@1|root,33ENF@2|Bacteria	2|Bacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
SRR25158456_k127_2444171_7	1122179.KB890467_gene626	1.022e-30	143.0	COG1672@1|root,COG3064@1|root,COG4886@1|root,COG1672@2|Bacteria,COG3064@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K06921,ko:K17266	-	-	-	-	ko00000,ko04147	-	-	-	LRR_4,Trans_reg_C
SRR25158456_k127_2444171_2	404589.Anae109_2830	2.998e-186	591.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,430G4@68525|delta/epsilon subdivisions,2WVMP@28221|Deltaproteobacteria,2YZCC@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM DNA primase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2444171_4	861299.J421_1029	1.96e-140	455.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	2|Bacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158456_k127_2444171_3	404589.Anae109_4038	1.331e-171	545.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,438FV@68525|delta/epsilon subdivisions,2X3QT@28221|Deltaproteobacteria,2YWVJ@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158456_k127_2446115_2	1499967.BAYZ01000075_gene2072	9.735e-21	98.0	COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158456_k127_2446115_0	247633.GP2143_09320	7.448e-34	152.0	COG0624@1|root,COG0624@2|Bacteria,1R40H@1224|Proteobacteria,1SMXB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158456_k127_2446115_1	1128421.JAGA01000003_gene3091	1.572e-28	134.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_2446115_3	1382356.JQMP01000003_gene1868	1.103e-18	101.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_2450807_1	204669.Acid345_2433	8.194e-89	310.0	COG4206@1|root,COG4206@2|Bacteria,3Y3IJ@57723|Acidobacteria,2JHQY@204432|Acidobacteriia	204432|Acidobacteriia	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_2450807_6	472759.Nhal_2694	2.12e-68	245.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1RN39@1236|Gammaproteobacteria,1WWM3@135613|Chromatiales	135613|Chromatiales	S	PFAM Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158456_k127_2450807_0	1313301.AUGC01000003_gene2172	3.634e-114	397.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes	976|Bacteroidetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158456_k127_2450807_5	1242864.D187_007434	2.301e-71	255.0	2ETZI@1|root,33MGP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2450807_11	1254432.SCE1572_49350	1.542e-09	61.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158456_k127_2450807_10	251221.35213000	1.762e-12	73.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158456_k127_2450807_4	555778.Hneap_0491	2.985e-79	279.0	COG0438@1|root,COG0438@2|Bacteria,1RF3D@1224|Proteobacteria,1S2YK@1236|Gammaproteobacteria,1WY5B@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158456_k127_2450807_2	1415630.U771_16730	1.032e-87	309.0	COG3751@1|root,COG3751@2|Bacteria,1RAJ8@1224|Proteobacteria,1S3II@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2450807_8	595593.JREV01000037_gene3566	2.016e-48	192.0	COG2327@1|root,COG2327@2|Bacteria,2IR3S@201174|Actinobacteria,1WBFF@1268|Micrococcaceae	201174|Actinobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	ko:K16710	-	-	-	-	ko00000	-	-	-	PS_pyruv_trans
SRR25158456_k127_2450807_7	324057.Pjdr2_1479	7.467e-53	198.0	COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,4HCF8@91061|Bacilli,26VRP@186822|Paenibacillaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158456_k127_2450807_3	323848.Nmul_A2202	1.762e-79	282.0	COG0438@1|root,COG0438@2|Bacteria,1PJ7G@1224|Proteobacteria,2W2A5@28216|Betaproteobacteria,373ZR@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
SRR25158456_k127_2450807_9	323848.Nmul_A2201	1.734e-16	87.0	COG0521@1|root,COG0521@2|Bacteria,1NYTN@1224|Proteobacteria,2W4HV@28216|Betaproteobacteria,373YP@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2451528_6	926549.KI421517_gene3452	7.335e-83	287.0	COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,47K82@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SRR25158456_k127_2451528_16	760192.Halhy_4503	2.277e-18	91.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
SRR25158456_k127_2451528_1	1121943.KB899997_gene1720	1.59e-94	338.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1SZ0M@1236|Gammaproteobacteria,1XKZK@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158456_k127_2451528_0	338966.Ppro_0969	4.869e-108	359.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,43SXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
SRR25158456_k127_2451528_17	1121920.AUAU01000030_gene2713	4.491e-12	70.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2451528_15	204669.Acid345_1574	8.273e-19	94.0	COG2834@1|root,COG2834@2|Bacteria,3Y4XE@57723|Acidobacteria,2JJK4@204432|Acidobacteriia	204432|Acidobacteriia	M	outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
SRR25158456_k127_2451528_12	756499.Desde_2586	3.816e-55	198.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,24HUX@186801|Clostridia,261V6@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158456_k127_2451528_9	1125863.JAFN01000001_gene236	6.757e-79	275.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158456_k127_2451528_11	1267533.KB906733_gene3430	5.224e-56	201.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria,2JJ6A@204432|Acidobacteriia	204432|Acidobacteriia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158456_k127_2451528_7	335543.Sfum_1414	3.732e-81	294.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158456_k127_2451528_8	344747.PM8797T_29063	1.744e-79	278.0	COG0601@1|root,COG0601@2|Bacteria,2IYGR@203682|Planctomycetes	203682|Planctomycetes	P	transport systems	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158456_k127_2451528_3	335543.Sfum_1411	1.167e-91	323.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SRR25158456_k127_2451528_10	234267.Acid_7185	1.282e-72	271.0	COG3386@1|root,COG3386@2|Bacteria,3Y2G7@57723|Acidobacteria	57723|Acidobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2451528_5	1047013.AQSP01000140_gene2527	1.141e-83	301.0	COG1044@1|root,COG1044@2|Bacteria,2NQT1@2323|unclassified Bacteria	2|Bacteria	M	SpoIVB peptidase S55	-	-	2.7.7.24	ko:K00973,ko:K02414,ko:K21449	ko00521,ko00523,ko00525,ko01130,ko02040,map00521,map00523,map00525,map01130,map02040	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko02035	1.B.40.2	-	-	AMP-binding,APH,DUF4114,DUF4842,Hexapep,PP-binding,Peptidase_S55
SRR25158456_k127_2451528_4	247633.GP2143_10457	1.262e-88	306.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1J5IY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_2451528_14	1303518.CCALI_00810	1.698e-36	143.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP
SRR25158456_k127_2451528_2	1382359.JIAL01000001_gene2865	5.104e-92	311.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2451528_13	1379698.RBG1_1C00001G1364	1.126e-39	155.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
SRR25158456_k127_2451576_2	1237149.C900_01926	9.037e-67	239.0	COG3321@1|root,COG4221@1|root,COG3321@2|Bacteria,COG4221@2|Bacteria,4PKD5@976|Bacteroidetes,47XYI@768503|Cytophagia	976|Bacteroidetes	Q	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_2451576_0	1500893.JQNB01000001_gene2575	0.0	3292.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158456_k127_2451576_1	1174528.JH992893_gene5856	0.0	1090.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase
SRR25158456_k127_2451985_0	1121920.AUAU01000015_gene1127	2.705e-70	266.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria	57723|Acidobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
SRR25158456_k127_2451985_1	1499967.BAYZ01000195_gene3090	2.12e-18	99.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158456_k127_2453637_8	1173027.Mic7113_3743	4.734e-08	59.0	COG0296@1|root,COG0296@2|Bacteria,1G0N3@1117|Cyanobacteria,1H6Z3@1150|Oscillatoriales	1117|Cyanobacteria	G	4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158456_k127_2453637_1	1173022.Cri9333_4060	1.349e-299	937.0	COG0296@1|root,COG0296@2|Bacteria,1GD05@1117|Cyanobacteria,1HEAH@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158456_k127_2453637_5	264462.Bd2635	4.206e-78	268.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,43BHQ@68525|delta/epsilon subdivisions,2MTVP@213481|Bdellovibrionales,2X6W7@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	XdhC Rossmann domain	pcmU	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158456_k127_2453637_3	448385.sce5876	1.932e-148	480.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42RF2@68525|delta/epsilon subdivisions,2WP05@28221|Deltaproteobacteria,2YWCM@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158456_k127_2453637_2	1254432.SCE1572_35005	1.773e-180	579.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
SRR25158456_k127_2453637_7	1068978.AMETH_1604	3.039e-29	121.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4E5V4@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158456_k127_2453637_6	452637.Oter_0969	3.79e-35	153.0	COG2010@1|root,COG2010@2|Bacteria,46W25@74201|Verrucomicrobia,3K9VZ@414999|Opitutae	414999|Opitutae	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
SRR25158456_k127_2453637_0	1121013.P873_12785	4.867e-301	933.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,1SZTS@1236|Gammaproteobacteria,1X4EA@135614|Xanthomonadales	135614|Xanthomonadales	V	abc transporter atp-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_2453637_4	215803.DB30_1345	3.682e-136	441.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria,437FH@68525|delta/epsilon subdivisions,2X2N4@28221|Deltaproteobacteria,2YTXN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158456_k127_2456056_0	1278073.MYSTI_02060	0.0	1602.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_2459439_3	857087.Metme_0345	2.822e-32	138.0	COG1262@1|root,COG1262@2|Bacteria,1QY0H@1224|Proteobacteria	1224|Proteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_2459439_0	381666.H16_B1804	5.552e-165	522.0	COG2207@1|root,COG2207@2|Bacteria,1MY46@1224|Proteobacteria,2VKKU@28216|Betaproteobacteria,1K256@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
SRR25158456_k127_2459439_1	448385.sce1411	7.368e-122	394.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,43CIP@68525|delta/epsilon subdivisions,2X7SY@28221|Deltaproteobacteria,2Z3HB@29|Myxococcales	28221|Deltaproteobacteria	C	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_2459439_2	765911.Thivi_2266	2.847e-62	222.0	COG4636@1|root,COG4636@2|Bacteria,1NTAK@1224|Proteobacteria,1SM5Q@1236|Gammaproteobacteria,1X0G8@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_2460295_5	1267533.KB906735_gene4963	3.712e-77	281.0	COG4566@1|root,COG4566@2|Bacteria,3Y7GW@57723|Acidobacteria,2JMTG@204432|Acidobacteriia	204432|Acidobacteriia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_2460295_4	1267533.KB906735_gene4962	2.425e-100	339.0	COG4191@1|root,COG4191@2|Bacteria,3Y3JK@57723|Acidobacteria,2JIZX@204432|Acidobacteriia	204432|Acidobacteriia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3
SRR25158456_k127_2460295_2	1232410.KI421426_gene1400	1.299e-141	454.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,42PW8@68525|delta/epsilon subdivisions,2WKCT@28221|Deltaproteobacteria,43UTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158456_k127_2460295_1	395963.Bind_0016	7.044e-187	612.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,2TR9T@28211|Alphaproteobacteria,3NC4H@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	calB	-	1.2.1.68,1.2.99.10	ko:K00154,ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158456_k127_2460295_8	247633.GP2143_13971	6.052e-36	157.0	2FJFE@1|root,34B51@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2460295_3	1173026.Glo7428_1980	4.279e-119	396.0	COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158456_k127_2460295_6	1395587.P364_0119350	3.342e-56	206.0	2B0GJ@1|root,31SU3@2|Bacteria,1TRKY@1239|Firmicutes,4HEZQ@91061|Bacilli,26QBY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2460295_0	1403819.BATR01000075_gene2177	1.153e-270	854.0	COG1100@1|root,COG1100@2|Bacteria,46WGX@74201|Verrucomicrobia,2IVVW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	C-terminal of Roc, COR, domain	-	-	-	-	-	-	-	-	-	-	-	-	COR,Roc,TIR_2
SRR25158456_k127_2460295_7	1227488.C477_06261	1.466e-39	169.0	COG3119@1|root,arCOG02787@2157|Archaea,2XUWX@28890|Euryarchaeota,23S64@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1,3.1.6.6	ko:K01130,ko:K01133	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158456_k127_2460295_9	1123242.JH636435_gene2917	1.197e-20	109.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
SRR25158456_k127_2465414_2	335543.Sfum_3109	2.16e-12	79.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1N17V@1224|Proteobacteria,42PVC@68525|delta/epsilon subdivisions,2WKU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158456_k127_2465414_1	1120936.KB907214_gene4418	6.545e-16	91.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4EK5Q@85012|Streptosporangiales	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158456_k127_2465414_0	266117.Rxyl_0743	2.324e-133	436.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158456_k127_2473246_15	945713.IALB_0301	2.156e-12	66.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158456_k127_2473246_0	945713.IALB_0300	0.0	1058.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
SRR25158456_k127_2473246_9	521674.Plim_3844	3.402e-61	217.0	COG4894@1|root,COG4894@2|Bacteria,2J08U@203682|Planctomycetes	203682|Planctomycetes	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	Scramblase
SRR25158456_k127_2473246_1	861299.J421_3037	1.72e-230	722.0	COG1012@1|root,COG1012@2|Bacteria,1ZUF7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158456_k127_2473246_4	656024.FsymDg_0452	3.573e-98	360.0	COG1409@1|root,COG1409@2|Bacteria,2GP1M@201174|Actinobacteria	201174|Actinobacteria	I	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158456_k127_2473246_2	575540.Isop_3575	7.872e-184	587.0	COG0531@1|root,COG0531@2|Bacteria,2IXT5@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158456_k127_2473246_14	861299.J421_2999	9.727e-35	153.0	COG3542@1|root,COG3542@2|Bacteria,1ZV7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
SRR25158456_k127_2473246_11	1242864.D187_002652	4.737e-53	193.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM isochorismatase hydrolase	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158456_k127_2473246_6	1242864.D187_002653	1.398e-91	310.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	darR	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158456_k127_2473246_12	1198452.Jab_1c20640	8.81e-50	193.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
SRR25158456_k127_2473246_5	1408813.AYMG01000008_gene3924	1.383e-94	316.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,1IPY1@117747|Sphingobacteriia	976|Bacteroidetes	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	ytrE_3	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2473246_8	391596.PBAL39_01807	4.712e-89	311.0	COG0577@1|root,COG0577@2|Bacteria,4NI8K@976|Bacteroidetes,1IPHF@117747|Sphingobacteriia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_2473246_10	1356852.N008_19845	2.23e-57	226.0	COG0577@1|root,COG0577@2|Bacteria,4NHA3@976|Bacteroidetes,47JKZ@768503|Cytophagia	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_2473246_3	1166018.FAES_3422	3.77e-153	499.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia	976|Bacteroidetes	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_2473246_7	1227739.Hsw_2638	3.957e-91	315.0	COG5000@1|root,COG5000@2|Bacteria,4NFQN@976|Bacteroidetes,47KW9@768503|Cytophagia	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,PAS_8
SRR25158456_k127_2473246_13	497964.CfE428DRAFT_1495	2.06e-38	151.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158456_k127_2486155_0	448385.sce7812	1.473e-239	773.0	COG1413@1|root,COG4715@1|root,COG1413@2|Bacteria,COG4715@2|Bacteria,1Q3FQ@1224|Proteobacteria,4397W@68525|delta/epsilon subdivisions,2X4EW@28221|Deltaproteobacteria,2YYW3@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158456_k127_2486155_7	28444.JODQ01000006_gene555	1.981e-10	75.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,Trans_reg_C,WD40
SRR25158456_k127_2486155_4	391587.KAOT1_06682	2.065e-59	231.0	COG2211@1|root,COG5309@1|root,COG2211@2|Bacteria,COG5309@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia	976|Bacteroidetes	G	COG2211 Na melibiose symporter and related	uidB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
SRR25158456_k127_2486155_2	864073.HFRIS_010054	4.27e-69	243.0	29QWQ@1|root,30BX9@2|Bacteria,1RFVP@1224|Proteobacteria,2W3QK@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2486155_3	1380390.JIAT01000001_gene5116	1.015e-60	219.0	COG2267@1|root,COG2267@2|Bacteria,2I2IM@201174|Actinobacteria,4CQH4@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158456_k127_2486155_9	504472.Slin_3915	5.902e-08	66.0	COG1649@1|root,COG3386@1|root,COG1649@2|Bacteria,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,47PCY@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
SRR25158456_k127_2486155_6	1120949.KB903357_gene4875	1.59e-24	121.0	COG2755@1|root,COG3291@1|root,COG3828@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Laminin_G_3,Lipase_GDSL_2,PKD,VCBS
SRR25158456_k127_2486155_8	2045.KR76_05765	4.104e-10	74.0	COG1629@1|root,COG4771@2|Bacteria,2IN13@201174|Actinobacteria,4DREY@85009|Propionibacteriales	201174|Actinobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2486155_1	1278073.MYSTI_00047	6.581e-85	296.0	COG3386@1|root,COG3386@2|Bacteria,1NIN4@1224|Proteobacteria	1224|Proteobacteria	G	Major royal jelly protein	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158456_k127_2494516_0	1041159.AZUW01000009_gene4548	1.926e-209	670.0	COG2304@1|root,COG2304@2|Bacteria,1R7H7@1224|Proteobacteria	1224|Proteobacteria	O	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64,VWA,VWA_2
SRR25158456_k127_2494516_4	378806.STAUR_6968	1.987e-114	370.0	COG0262@1|root,COG0262@2|Bacteria,1NE59@1224|Proteobacteria	1224|Proteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158456_k127_2494516_7	1242864.D187_001863	2.241e-95	325.0	COG5006@1|root,COG5006@2|Bacteria,1MXR7@1224|Proteobacteria,439J2@68525|delta/epsilon subdivisions,2X4VJ@28221|Deltaproteobacteria,2YZPJ@29|Myxococcales	28221|Deltaproteobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158456_k127_2494516_8	1167006.UWK_03499	9.189e-92	307.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158456_k127_2494516_5	502025.Hoch_0330	3.606e-97	327.0	COG0462@1|root,COG0462@2|Bacteria,1NYN6@1224|Proteobacteria,430EG@68525|delta/epsilon subdivisions,2WVU6@28221|Deltaproteobacteria,2YY0P@29|Myxococcales	28221|Deltaproteobacteria	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
SRR25158456_k127_2494516_13	743721.Psesu_2705	1.407e-73	255.0	COG3861@1|root,COG3861@2|Bacteria,1MWBU@1224|Proteobacteria,1S1WP@1236|Gammaproteobacteria,1XCQG@135614|Xanthomonadales	135614|Xanthomonadales	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
SRR25158456_k127_2494516_6	243231.GSU2744	3.661e-97	331.0	COG0477@1|root,COG0477@2|Bacteria,1QWSX@1224|Proteobacteria,43C55@68525|delta/epsilon subdivisions,2X7FI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_2494516_3	204669.Acid345_1212	5.667e-120	395.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria,2JI6S@204432|Acidobacteriia	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158456_k127_2494516_10	1121920.AUAU01000004_gene629	1.079e-85	291.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158456_k127_2494516_1	1379698.RBG1_1C00001G0513	1.162e-147	481.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158456_k127_2494516_14	102232.GLO73106DRAFT_00029750	3.029e-56	224.0	COG1404@1|root,COG2373@1|root,COG1404@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Peptidase_S8,SLH,SdrD_B
SRR25158456_k127_2494516_12	1128421.JAGA01000002_gene1141	6.742e-77	266.0	COG1024@1|root,COG1024@2|Bacteria,2NR3A@2323|unclassified Bacteria	2|Bacteria	I	Enoyl-CoA hydratase/isomerase	atuE	-	4.2.1.18,4.2.1.57	ko:K13766,ko:K13779	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R02085,R03493	RC00941,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158456_k127_2494516_2	930169.B5T_01797	2.72e-143	481.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1XISG@135619|Oceanospirillales	135619|Oceanospirillales	I	Acetyl propionyl-CoA carboxylase, alpha subunit	-	-	6.4.1.5	ko:K13777	ko00281,map00281	-	R03494	RC00367,RC00942	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158456_k127_2494516_22	331113.SNE_A20910	6.309e-08	59.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR25158456_k127_2494516_21	1300143.CCAV010000001_gene919	1.557e-08	57.0	2EJDT@1|root,33D4U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2494516_15	443143.GM18_0461	6.568e-56	205.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,42ZR0@68525|delta/epsilon subdivisions,2WT3B@28221|Deltaproteobacteria,43UQ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_2494516_11	443143.GM18_0462	5.058e-83	297.0	COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158456_k127_2494516_19	261292.Nit79A3_1874	6.915e-28	132.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,2VWDQ@28216|Betaproteobacteria,3749I@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2494516_17	56780.SYN_01954	2.658e-53	207.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
SRR25158456_k127_2494516_16	1047013.AQSP01000122_gene2226	9.883e-54	214.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	vsrD	-	-	ko:K02282,ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR25158456_k127_2494516_24	596152.DesU5LDRAFT_0984	3.731e-06	55.0	COG0745@1|root,COG0745@2|Bacteria,1N09M@1224|Proteobacteria,42TFZ@68525|delta/epsilon subdivisions,2WQ8P@28221|Deltaproteobacteria,2MCFQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158456_k127_2494516_9	446470.Snas_0537	1.422e-86	322.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
SRR25158456_k127_2513601_2	671143.DAMO_0916	4.72e-23	104.0	COG0521@1|root,COG0521@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2513601_3	313590.MED134_10146	3.74e-06	53.0	COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1I1YY@117743|Flavobacteriia,37F89@326319|Dokdonia	976|Bacteroidetes	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158456_k127_2513601_1	1089548.KI783301_gene2277	1.66e-42	167.0	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,3WFTM@539002|Bacillales incertae sedis	91061|Bacilli	K	YsiA-like protein, C-terminal region	fadR	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRR25158456_k127_2513601_0	234267.Acid_2705	2.432e-140	468.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158456_k127_2514834_1	33876.JNXY01000001_gene5830	6.34e-116	395.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,4DC84@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158456_k127_2514834_4	595460.RRSWK_03216	5.778e-09	65.0	COG2202@1|root,COG4566@1|root,COG2202@2|Bacteria,COG4566@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,GerE,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158456_k127_2514834_0	1047013.AQSP01000132_gene1707	7.688e-123	410.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	rfbB	-	3.6.3.38,3.6.3.40	ko:K01990,ko:K09689,ko:K09691,ko:K09693	ko02010,map02010	M00249,M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158456_k127_2514834_3	1155718.KB891887_gene6716	4.963e-33	142.0	COG0657@1|root,COG4257@1|root,COG0657@2|Bacteria,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Abhydrolase_3
SRR25158456_k127_2514834_2	639030.JHVA01000001_gene3471	5.78e-37	145.0	COG0330@1|root,COG0330@2|Bacteria,3Y33E@57723|Acidobacteria,2JHPX@204432|Acidobacteriia	204432|Acidobacteriia	O	SMART band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158456_k127_2519536_0	1121920.AUAU01000013_gene1763	4.045e-101	364.0	COG0515@1|root,COG0515@2|Bacteria	1121920.AUAU01000013_gene1763|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2519536_4	589865.DaAHT2_1558	8.738e-35	145.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria,2MIYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158456_k127_2519536_3	485913.Krac_4529	4.764e-50	194.0	COG2329@1|root,COG2329@2|Bacteria,2G8Z3@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
SRR25158456_k127_2519536_1	379066.GAU_0496	4.226e-58	214.0	COG0609@1|root,COG0609@2|Bacteria,1ZTAA@142182|Gemmatimonadetes	2|Bacteria	P	FecCD transport family	btuC	-	3.6.3.34	ko:K02013,ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	FecCD
SRR25158456_k127_2519536_2	1089553.Tph_c15800	1.022e-50	189.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,42FXA@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158456_k127_2540863_2	340177.Cag_1752	1.9e-19	93.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158456_k127_2540863_3	290315.Clim_0591	6.757e-11	65.0	2EKK5@1|root,33EA0@2|Bacteria	2|Bacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158456_k127_2540863_0	666685.R2APBS1_0146	4.291e-152	493.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1X5E6@135614|Xanthomonadales	135614|Xanthomonadales	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_2540863_1	366602.Caul_0107	3.249e-122	408.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_2541345_4	983548.Krodi_1329	3.417e-19	102.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,37E3I@326319|Dokdonia	976|Bacteroidetes	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
SRR25158456_k127_2541345_7	909663.KI867150_gene2460	1.028e-08	58.0	COG2002@1|root,COG2002@2|Bacteria,1NFWR@1224|Proteobacteria,42WSB@68525|delta/epsilon subdivisions,2WSD6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158456_k127_2541345_3	306281.AJLK01000020_gene2982	5.634e-48	176.0	COG1670@1|root,COG1670@2|Bacteria,1GHZ7@1117|Cyanobacteria,1JJ64@1189|Stigonemataceae	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158456_k127_2541345_5	1300345.LF41_2967	6.788e-15	85.0	2EME3@1|root,33F2Y@2|Bacteria,1P6VT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2541345_0	1183438.GKIL_2224	5.451e-248	781.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
SRR25158456_k127_2541345_1	1121904.ARBP01000013_gene445	1.118e-151	492.0	COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	alkH	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158456_k127_2541345_2	1459636.NTE_00289	1.855e-74	265.0	COG3039@1|root,arCOG02751@2157|Archaea	2157|Archaea	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158456_k127_2541345_6	255470.cbdbA624	3.063e-11	73.0	2E9WR@1|root,3342G@2|Bacteria,2GASC@200795|Chloroflexi,34D85@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Family of unknown function (DUF5343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5343
SRR25158456_k127_2541345_8	1349767.GJA_4798	1.86e-06	57.0	COG1476@1|root,COG1476@2|Bacteria,1NPDH@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158456_k127_2545351_7	312309.VF_0875	1.297e-07	59.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RPEM@1236|Gammaproteobacteria,1XUK7@135623|Vibrionales	135623|Vibrionales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	-	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
SRR25158456_k127_2545351_5	1232437.KL661980_gene3716	1.301e-20	96.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MKCK@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158456_k127_2545351_1	398767.Glov_2011	4.085e-134	437.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158456_k127_2545351_6	911239.CF149_20478	4.849e-08	63.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
SRR25158456_k127_2545351_3	882.DVU_3395	4.54e-74	268.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158456_k127_2545351_4	264462.Bd1027	3.101e-54	213.0	COG2605@1|root,COG2605@2|Bacteria,1Q1GI@1224|Proteobacteria,42TJZ@68525|delta/epsilon subdivisions,2MT41@213481|Bdellovibrionales,2WQNP@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158456_k127_2545351_8	335543.Sfum_1625	0.0001281	55.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SRR25158456_k127_2545351_0	861299.J421_6006	1.29e-169	562.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_2545351_2	1267533.KB906733_gene3108	8.125e-96	343.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158456_k127_254923_2	1278073.MYSTI_00257	1.866e-118	393.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1MVGV@1224|Proteobacteria,42WJ6@68525|delta/epsilon subdivisions,2WQ9K@28221|Deltaproteobacteria,2YXTM@29|Myxococcales	28221|Deltaproteobacteria	PT	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158456_k127_254923_4	861299.J421_1461	1.089e-76	282.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
SRR25158456_k127_254923_5	234267.Acid_4820	9.527e-33	130.0	COG3682@1|root,COG3682@2|Bacteria,3Y8BB@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158456_k127_254923_1	448385.sce2299	9.645e-173	556.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YWKI@29|Myxococcales	28221|Deltaproteobacteria	H	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158456_k127_254923_0	1122164.JHWF01000007_gene1152	1.036e-191	619.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,1RNNA@1236|Gammaproteobacteria,1JDG7@118969|Legionellales	118969|Legionellales	O	Peptidase family M13	pepO	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158456_k127_254923_6	1449976.KALB_7891	1.311e-10	66.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DXWN@85010|Pseudonocardiales	201174|Actinobacteria	KT	Response regulator receiver	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_254923_7	768671.ThimaDRAFT_3971	1.546e-06	59.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,1WYA9@135613|Chromatiales	135613|Chromatiales	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
SRR25158456_k127_254923_3	1340493.JNIF01000003_gene4835	3.279e-110	378.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	ampH	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158456_k127_2550617_5	211114.JOEF01000018_gene6201	7.536e-10	70.0	2C4IS@1|root,2Z81U@2|Bacteria,2GP0Z@201174|Actinobacteria,4DZ19@85010|Pseudonocardiales	201174|Actinobacteria	S	Lantibiotic dehydratase, C terminus	-	-	-	ko:K20483	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	Lant_dehydr_C,Lant_dehydr_N
SRR25158456_k127_2550617_2	502025.Hoch_4144	2.664e-43	176.0	COG4403@1|root,COG4403@2|Bacteria,1R8AJ@1224|Proteobacteria,43EZ6@68525|delta/epsilon subdivisions,2WYJK@28221|Deltaproteobacteria,2YZ2R@29|Myxococcales	28221|Deltaproteobacteria	V	Lanthionine synthetase C-like protein	-	-	-	ko:K20484	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	LANC_like
SRR25158456_k127_2550617_0	161156.JQKW01000014_gene237	1.36e-87	331.0	COG3604@1|root,COG3604@2|Bacteria,2GGRI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	GAF domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158456_k127_2550617_1	204669.Acid345_0604	4.625e-71	269.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_2558002_1	272623.L25787	7.683e-87	297.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1YB9R@1357|Lactococcus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158456_k127_2558002_3	234267.Acid_2173	4.927e-46	183.0	COG3391@1|root,COG3391@2|Bacteria,3Y866@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2558002_4	338963.Pcar_1552	2.655e-29	122.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria,43SQA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RimP C-terminal SH3 domain	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158456_k127_2558002_0	404380.Gbem_1300	8.125e-95	337.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,43U8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SRR25158456_k127_2558002_2	883.DvMF_2513	1.627e-77	282.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2M88K@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158456_k127_2561666_2	1944.JOAZ01000008_gene964	2.695e-120	414.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,41A0K@629295|Streptomyces griseus group	201174|Actinobacteria	J	tRNA synthetase B5 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158456_k127_2561666_3	1944.JOAZ01000008_gene963	2.405e-100	338.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,417G5@629295|Streptomyces griseus group	2|Bacteria	J	tRNA synthetases class II core domain (F)	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	FDX-ACB,Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158456_k127_2561666_0	290397.Adeh_2937	8.934e-205	659.0	COG3227@1|root,COG3227@2|Bacteria,1QXPY@1224|Proteobacteria,43E6J@68525|delta/epsilon subdivisions,2X7H9@28221|Deltaproteobacteria,2Z3GG@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M36
SRR25158456_k127_2561666_1	1120999.JONM01000006_gene2487	4.466e-136	449.0	2DBCY@1|root,2Z8GH@2|Bacteria,1RB41@1224|Proteobacteria	1224|Proteobacteria	S	Common central domain of tyrosinase	-	-	1.10.3.1,1.14.18.1	ko:K00422,ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00031,R00045,R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	PPO1_DWL,PPO1_KFDV,Tyrosinase
SRR25158456_k127_2576383_1	861299.J421_0942	2.513e-39	157.0	COG0003@1|root,COG0003@2|Bacteria,1ZVAB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158456_k127_2576383_2	1449076.JOOE01000004_gene117	1.063e-34	149.0	COG0604@1|root,COG0604@2|Bacteria,1QY0U@1224|Proteobacteria	1224|Proteobacteria	C	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
SRR25158456_k127_2576383_6	479434.Sthe_0877	2.086e-22	106.0	2BI1G@1|root,32C67@2|Bacteria,2G930@200795|Chloroflexi	200795|Chloroflexi	S	Gas vesicle synthesis protein GvpL/GvpF	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
SRR25158456_k127_2576383_7	1121422.AUMW01000016_gene2089	2.475e-11	65.0	2DJCY@1|root,305NK@2|Bacteria,1TYFT@1239|Firmicutes,256D7@186801|Clostridia,266HZ@186807|Peptococcaceae	186801|Clostridia	S	Gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158456_k127_2576383_4	861299.J421_0938	5.63e-26	112.0	arCOG06390@1|root,330IR@2|Bacteria	2|Bacteria	S	Gas vesicle protein K	gvpK	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle,GvpK
SRR25158456_k127_2576383_5	861299.J421_0937	4.867e-24	105.0	2E5BC@1|root,3303G@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpJ	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158456_k127_2576383_3	204669.Acid345_2404	1.116e-29	119.0	arCOG03092@1|root,32YMQ@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
SRR25158456_k127_2576383_0	234267.Acid_1536	1.981e-203	652.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158456_k127_2576858_2	330214.NIDE2215	2.008e-47	184.0	COG2503@1|root,COG2503@2|Bacteria	2|Bacteria	M	HAD superfamily, subfamily IIIB (Acid phosphatase)	hel	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRR25158456_k127_2576858_0	1356852.N008_04055	1.955e-183	630.0	COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_2576858_1	404589.Anae109_1185	3.22e-114	383.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
SRR25158456_k127_2577726_1	443144.GM21_2024	7.382e-91	317.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158456_k127_2577726_2	314285.KT71_06864	3.431e-23	104.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria,1SF92@1236|Gammaproteobacteria,1JA39@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158456_k127_2577726_0	1379698.RBG1_1C00001G0471	9.992e-226	710.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158456_k127_258684_0	1267535.KB906767_gene2747	5.128e-156	502.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158456_k127_258684_5	903818.KI912269_gene297	4.621e-32	128.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria	57723|Acidobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158456_k127_258684_2	383372.Rcas_3070	2.624e-63	232.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158456_k127_258684_1	1304275.C41B8_01385	3.288e-135	440.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158456_k127_258684_4	765869.BDW_08490	1.832e-49	197.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2MTRQ@213481|Bdellovibrionales,2WQM8@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PA,Peptidase_S8
SRR25158456_k127_258684_3	1300345.LF41_3131	5.139e-57	209.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1MW5W@1224|Proteobacteria,1S8RX@1236|Gammaproteobacteria,1X53X@135614|Xanthomonadales	135614|Xanthomonadales	E	serine protease	-	-	-	-	-	-	-	-	-	-	-	-	PA
SRR25158456_k127_2588344_8	497964.CfE428DRAFT_3010	9.502e-09	60.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
SRR25158456_k127_2588344_6	378806.STAUR_4148	1.139e-35	151.0	COG2850@1|root,COG2850@2|Bacteria,1Q2K0@1224|Proteobacteria,4386U@68525|delta/epsilon subdivisions,2X3GQ@28221|Deltaproteobacteria,2YW0S@29|Myxococcales	28221|Deltaproteobacteria	S	Cupin superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158456_k127_2588344_0	483219.LILAB_26400	1.901e-136	447.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YVF7@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,Aminotran_1_2
SRR25158456_k127_2588344_3	483219.LILAB_26415	8.154e-87	316.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2YUHA@29|Myxococcales	28221|Deltaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158456_k127_2588344_4	1408452.JAGZ01000004_gene1483	3.198e-71	244.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,23AEJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	MaoC like domain	-	-	4.2.1.56	ko:K18290	ko00660,map00660	-	R02491	RC00730	ko00000,ko00001,ko01000	-	-	-	MaoC_dehydratas
SRR25158456_k127_2588344_5	1463936.JOJI01000002_gene2892	2.5e-64	231.0	COG2301@1|root,COG2301@2|Bacteria,2GJ6Y@201174|Actinobacteria	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.25,4.1.3.34	ko:K01644,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158456_k127_2588344_9	68260.JOAY01000019_gene1519	6.377e-05	55.0	COG2308@1|root,COG2308@2|Bacteria,2GP4E@201174|Actinobacteria	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2588344_2	448385.sce2385	6.579e-97	355.0	COG1020@1|root,COG1020@2|Bacteria,1NSJT@1224|Proteobacteria,43C6Y@68525|delta/epsilon subdivisions,2X7H5@28221|Deltaproteobacteria,2YY62@29|Myxococcales	28221|Deltaproteobacteria	Q	Lantibiotic dehydratase, C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Lant_dehydr_N
SRR25158456_k127_2588344_7	29073.XP_008683576.1	8.518e-13	79.0	KOG2132@1|root,KOG2132@2759|Eukaryota,38CB5@33154|Opisthokonta,3B9PX@33208|Metazoa,3CUMR@33213|Bilateria,488A5@7711|Chordata,49239@7742|Vertebrata,3JF38@40674|Mammalia,3EI1S@33554|Carnivora	33208|Metazoa	BT	demethylase 8	KDM8	GO:0000086,GO:0000278,GO:0003674,GO:0003682,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006325,GO:0006355,GO:0006464,GO:0006482,GO:0006807,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008214,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016491,GO:0016569,GO:0016570,GO:0016577,GO:0016705,GO:0016706,GO:0019219,GO:0019222,GO:0019538,GO:0022402,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0032451,GO:0032452,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044839,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051213,GO:0051252,GO:0051254,GO:0051276,GO:0051864,GO:0055114,GO:0060255,GO:0065007,GO:0070013,GO:0070076,GO:0070544,GO:0070988,GO:0071704,GO:0071840,GO:0080090,GO:0140096,GO:1901564,GO:1902680,GO:1903047,GO:1903506,GO:1903508,GO:2000112,GO:2001141	1.14.11.27	ko:K10277	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	Cupin_8
SRR25158456_k127_2588344_1	1379270.AUXF01000007_gene889	7.5e-112	365.0	COG4947@1|root,COG4947@2|Bacteria,1ZU4F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158456_k127_2606870_1	243274.THEMA_01820	1.588e-67	233.0	COG0552@1|root,COG0552@2|Bacteria,2GBXG@200918|Thermotogae	200918|Thermotogae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158456_k127_2606870_5	715226.ABI_02260	1.053e-05	49.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_2606870_3	28072.Nos7524_1903	2.293e-09	63.0	COG3744@1|root,COG3744@2|Bacteria,1G5SF@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_2606870_2	469371.Tbis_2366	1.376e-22	107.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158456_k127_2606870_0	330214.NIDE2333	5.563e-77	277.0	COG1032@1|root,COG1032@2|Bacteria,3J16J@40117|Nitrospirae	40117|Nitrospirae	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158456_k127_2606870_4	340177.Cag_1937	1.376e-06	57.0	COG3637@1|root,COG3637@2|Bacteria,1FE25@1090|Chlorobi	1090|Chlorobi	M	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
SRR25158456_k127_2614280_0	1123279.ATUS01000001_gene1617	3.1e-254	831.0	COG4773@1|root,COG4773@2|Bacteria,1QURT@1224|Proteobacteria,1SM3F@1236|Gammaproteobacteria,1J505@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_2614280_4	861299.J421_1738	3.494e-113	377.0	COG0665@1|root,COG0665@2|Bacteria,1ZSZG@142182|Gemmatimonadetes	2|Bacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158456_k127_2614280_12	861299.J421_1738	8.089e-24	104.0	COG0665@1|root,COG0665@2|Bacteria,1ZSZG@142182|Gemmatimonadetes	2|Bacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158456_k127_2614280_11	46234.ANA_C10633	8.71e-26	111.0	COG2442@1|root,COG2442@2|Bacteria,1G87F@1117|Cyanobacteria,1HPFU@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_2614280_10	118173.KB235914_gene1628	2.257e-35	141.0	COG4634@1|root,COG4634@2|Bacteria,1G7D7@1117|Cyanobacteria,1HD5B@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2614280_3	91464.S7335_3669	2.842e-123	417.0	COG1231@1|root,COG1231@2|Bacteria,1FZVN@1117|Cyanobacteria,1H47E@1129|Synechococcus	1117|Cyanobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158456_k127_2614280_9	515620.EUBELI_00208	3.85e-39	161.0	2EZAY@1|root,33SGD@2|Bacteria,1VSFZ@1239|Firmicutes,24XMZ@186801|Clostridia	186801|Clostridia	S	FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
SRR25158456_k127_2614280_5	1122185.N792_01200	2.46e-89	323.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RQ1P@1236|Gammaproteobacteria,1X5A0@135614|Xanthomonadales	135614|Xanthomonadales	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158456_k127_2614280_2	234267.Acid_0057	1.36e-137	456.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158456_k127_2614280_6	1304880.JAGB01000001_gene763	7.739e-82	290.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158456_k127_2614280_1	1453500.AT05_05035	4.37e-141	453.0	COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1HX2F@117743|Flavobacteriia	976|Bacteroidetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
SRR25158456_k127_2614280_7	378806.STAUR_6609	1.213e-49	196.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,42UMS@68525|delta/epsilon subdivisions,2WQA3@28221|Deltaproteobacteria,2YVD7@29|Myxococcales	28221|Deltaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287,ko:K18589	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	DHFR_1
SRR25158456_k127_2617078_1	234267.Acid_7247	2.745e-56	202.0	COG1595@1|root,COG1595@2|Bacteria,3Y815@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_2617078_3	278963.ATWD01000001_gene2875	1.326e-25	120.0	2BI39@1|root,32C8D@2|Bacteria,3Y85Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2617078_0	639030.JHVA01000001_gene1848	1.617e-78	279.0	COG1413@1|root,COG1413@2|Bacteria,3Y7PB@57723|Acidobacteria	57723|Acidobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158456_k127_2617078_2	639030.JHVA01000001_gene1847	2.26e-27	121.0	COG1413@1|root,COG1413@2|Bacteria,3Y76M@57723|Acidobacteria	57723|Acidobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158456_k127_2618330_1	1121957.ATVL01000006_gene2786	2.815e-120	402.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158456_k127_2618330_0	378806.STAUR_5205	3.772e-279	871.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YXXC@29|Myxococcales	28221|Deltaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158456_k127_2618330_3	522306.CAP2UW1_1340	4.823e-61	220.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
SRR25158456_k127_2618330_2	234267.Acid_1587	2.838e-100	339.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158456_k127_2619386_2	330214.NIDE4157	2.359e-25	115.0	COG3824@1|root,COG3824@2|Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158456_k127_2619386_0	518766.Rmar_0629	3.25e-276	884.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
SRR25158456_k127_2619386_1	1459636.NTE_00013	1.024e-72	250.0	COG2085@1|root,arCOG00457@2157|Archaea	2157|Archaea	S	NADPH-dependent F420 reductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored,HTH_10
SRR25158456_k127_2620971_0	1237149.C900_01919	0.0	2078.0	COG1028@1|root,COG2898@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2898@2|Bacteria,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,47XYI@768503|Cytophagia	976|Bacteroidetes	Q	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase,DUF2156,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_2620971_1	1297742.A176_00334	0.0	1105.0	COG3321@1|root,COG3321@2|Bacteria,1Q52Y@1224|Proteobacteria,43A3Z@68525|delta/epsilon subdivisions,2XA2T@28221|Deltaproteobacteria,2YTU6@29|Myxococcales	28221|Deltaproteobacteria	Q	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158456_k127_2621718_6	765420.OSCT_1196	2.219e-30	122.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158456_k127_2621718_8	706587.Desti_4241	8.735e-23	102.0	COG2361@1|root,COG2361@2|Bacteria,1NA32@1224|Proteobacteria,43B8M@68525|delta/epsilon subdivisions,2X6MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158456_k127_2621718_7	411479.BACUNI_01264	1.588e-23	110.0	COG4632@1|root,COG4632@2|Bacteria,4NQZB@976|Bacteroidetes,2FP6A@200643|Bacteroidia,4APG3@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
SRR25158456_k127_2621718_1	518766.Rmar_1316	2.908e-95	323.0	COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1FJIC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158456_k127_2621718_2	926569.ANT_28680	1.556e-90	317.0	COG2746@1|root,COG2746@2|Bacteria,2G6YM@200795|Chloroflexi	200795|Chloroflexi	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
SRR25158456_k127_2621718_4	667014.Thein_1148	2.918e-53	194.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158456_k127_2621718_5	1207076.ALAT01000143_gene484	6.399e-50	179.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,1Z33C@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
SRR25158456_k127_2621718_9	1121017.AUFG01000067_gene153	9.648e-20	94.0	2DPPE@1|root,332VJ@2|Bacteria,2IN30@201174|Actinobacteria,4FGZI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158456_k127_2621718_3	1144342.PMI40_04802	1.704e-77	274.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,47340@75682|Oxalobacteraceae	28216|Betaproteobacteria	LU	DNA recombination-mediator protein A	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158456_k127_2621718_10	439235.Dalk_3174	0.0002651	49.0	COG0457@1|root,COG0457@2|Bacteria	439235.Dalk_3174|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2621718_0	1047013.AQSP01000115_gene336	7.218e-142	487.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2,TolB_N
SRR25158456_k127_2640056_2	251221.35211765	1.828e-148	505.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_2640056_3	234267.Acid_3991	2.223e-136	473.0	COG0577@1|root,COG0577@2|Bacteria,3Y44G@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_2640056_5	1267535.KB906767_gene632	8.845e-110	359.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2640056_4	251221.35211836	4.611e-122	404.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_2640056_1	945713.IALB_1403	2.591e-149	501.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	rfbB	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158456_k127_2640056_0	269796.Rru_A2116	2.48e-159	515.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158456_k127_2641390_0	1340493.JNIF01000003_gene4543	0.0	1034.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158456_k127_2641390_2	56110.Oscil6304_0870	1.226e-42	181.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
SRR25158456_k127_2641390_1	404589.Anae109_1105	4.991e-112	394.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_2641390_3	483219.LILAB_33925	4.789e-31	138.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158456_k127_2645127_5	1347086.CCBA010000025_gene3066	7.468e-36	146.0	COG2755@1|root,COG2755@2|Bacteria,1UZKM@1239|Firmicutes,4HD6X@91061|Bacilli,1ZCPP@1386|Bacillus	91061|Bacilli	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158456_k127_2645127_1	1329516.JPST01000003_gene1081	1.118e-84	292.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,27BKK@186824|Thermoactinomycetaceae	91061|Bacilli	V	ATP binding cassette transporter ABC protein	bcrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2645127_3	1163407.UU7_02017	8.441e-56	209.0	COG1359@1|root,COG1359@2|Bacteria,1REMS@1224|Proteobacteria,1TI3B@1236|Gammaproteobacteria,1X7PQ@135614|Xanthomonadales	135614|Xanthomonadales	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
SRR25158456_k127_2645127_4	1298858.AUEL01000006_gene2072	1.348e-41	158.0	2D579@1|root,32TID@2|Bacteria,1RH2N@1224|Proteobacteria,2U9TR@28211|Alphaproteobacteria,43M58@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2645127_0	1267533.KB906741_gene551	4.971e-170	546.0	COG1167@1|root,COG1167@2|Bacteria,3Y3WK@57723|Acidobacteria,2JI7P@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158456_k127_2645127_2	1118054.CAGW01000089_gene3484	8.647e-83	286.0	COG1277@1|root,COG1277@2|Bacteria,1TRV1@1239|Firmicutes,4HBBV@91061|Bacilli,26SYW@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter permease	bcrB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158456_k127_2645127_6	1234364.AMSF01000025_gene3750	4.406e-33	132.0	COG2199@1|root,COG2199@2|Bacteria,1P1TG@1224|Proteobacteria,1SS2G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158456_k127_2646244_0	1124780.ANNU01000028_gene955	2.503e-61	230.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158456_k127_2646244_1	316274.Haur_3712	1.321e-60	225.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_2646244_2	1000565.METUNv1_03770	3.463e-42	166.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2VUX2@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_7C,Glycos_transf_2,PIG-L
SRR25158456_k127_264908_9	395965.Msil_0449	6.116e-08	66.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,2U1FH@28211|Alphaproteobacteria,3N9PC@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_264908_3	864702.OsccyDRAFT_1593	3.406e-77	267.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_264908_7	1242864.D187_007063	7.963e-24	118.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_264908_6	498761.HM1_1963	3.871e-47	178.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia	186801|Clostridia	H	Siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158456_k127_264908_0	1379698.RBG1_1C00001G1453	4.283e-175	557.0	COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081,iIT341.HP0183	SHMT
SRR25158456_k127_264908_4	869210.Marky_0288	3.219e-69	250.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158456_k127_264908_2	1121918.ARWE01000001_gene2325	4.976e-114	374.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,43S80@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158456_k127_264908_1	391625.PPSIR1_08217	3.295e-127	415.0	COG0057@1|root,COG0057@2|Bacteria,1N2N1@1224|Proteobacteria	1224|Proteobacteria	G	Glyceraldehyde-3-phosphate dehydrogenase	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_N,Gp_dh_C
SRR25158456_k127_264908_8	649638.Trad_2819	1.06e-19	94.0	COG4113@1|root,COG4113@2|Bacteria,1WKRQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_264908_5	401053.AciPR4_1404	4.168e-50	182.0	COG0691@1|root,COG0691@2|Bacteria,3Y4CC@57723|Acidobacteria,2JJ48@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158456_k127_2659638_0	215803.DB30_2226	0.0	1187.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SRR25158456_k127_2659638_5	1192034.CAP_5614	4.115e-39	169.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,42VB2@68525|delta/epsilon subdivisions,2WS8S@28221|Deltaproteobacteria,2Z036@29|Myxococcales	28221|Deltaproteobacteria	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
SRR25158456_k127_2659638_1	203119.Cthe_3075	1.197e-178	572.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,249KV@186801|Clostridia,3WGCX@541000|Ruminococcaceae	186801|Clostridia	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158456_k127_2659638_4	204669.Acid345_4616	4.238e-97	325.0	COG2321@1|root,COG2321@2|Bacteria,3Y3WQ@57723|Acidobacteria,2JIYI@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158456_k127_2659638_14	1169143.KB911038_gene6141	3.199e-09	69.0	COG1881@1|root,COG1881@2|Bacteria,1N7JI@1224|Proteobacteria,2W2HZ@28216|Betaproteobacteria,1K75V@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158456_k127_2659638_8	67275.JOAP01000020_gene2075	2.15e-22	111.0	28SH2@1|root,2ZETH@2|Bacteria,2I3DB@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158456_k127_2659638_7	580332.Slit_1516	1.533e-27	131.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158456_k127_2659638_6	485913.Krac_5622	9.384e-37	139.0	COG5207@1|root,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
SRR25158456_k127_2659638_3	1380393.JHVP01000007_gene4485	2.693e-123	426.0	COG2340@1|root,COG4409@1|root,COG2340@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	BNR_2,CBM_35,CW_binding_2,DUF4214,Peptidase_M10
SRR25158456_k127_2659638_12	745411.B3C1_02550	1.754e-14	88.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1J8B4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1404 Subtilisin-like serine proteases	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	CBM_5_12,Inhibitor_I9,PKD,PPC,Peptidase_S8
SRR25158456_k127_2659638_2	1380393.JHVP01000007_gene4485	2.484e-133	464.0	COG2340@1|root,COG4409@1|root,COG2340@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	BNR_2,CBM_35,CW_binding_2,DUF4214,Peptidase_M10
SRR25158456_k127_2659638_9	1234364.AMSF01000086_gene2832	1.836e-19	105.0	COG3291@1|root,COG3291@2|Bacteria,1QVQS@1224|Proteobacteria,1T2H8@1236|Gammaproteobacteria,1XD56@135614|Xanthomonadales	135614|Xanthomonadales	O	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC
SRR25158456_k127_2659638_13	316274.Haur_4361	2.351e-13	85.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_6,PEGA,Peptidase_S8
SRR25158456_k127_2673788_0	864069.MicloDRAFT_00060470	9.73e-164	554.0	COG0178@1|root,COG0178@2|Bacteria,1MX79@1224|Proteobacteria,2TTXN@28211|Alphaproteobacteria,1JT9I@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158456_k127_2673788_1	626887.J057_01524	1.661e-87	311.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,466D6@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Reversible hydration of carbon dioxide	can	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_0115,iSbBS512_1146.SbBS512_E0119	Pro_CA
SRR25158456_k127_2673788_4	379066.GAU_0215	3.646e-29	128.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158456_k127_2673788_8	401053.AciPR4_3880	2.202e-07	65.0	COG0457@1|root,COG0457@2|Bacteria,3Y3EM@57723|Acidobacteria,2JIDA@204432|Acidobacteriia	204432|Acidobacteriia	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_2673788_5	1121033.AUCF01000016_gene5441	5.927e-23	116.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2TS2A@28211|Alphaproteobacteria,2JT2W@204441|Rhodospirillales	204441|Rhodospirillales	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_4,TPR_7
SRR25158456_k127_2673788_2	1408419.JHYG01000015_gene2550	3.109e-45	185.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2JRGK@204441|Rhodospirillales	204441|Rhodospirillales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,Pkinase
SRR25158456_k127_2673788_7	1122599.AUGR01000027_gene1286	3.229e-11	78.0	COG4254@1|root,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,1S1E7@1236|Gammaproteobacteria,1XIYX@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
SRR25158456_k127_2673788_6	670487.Ocepr_2061	7.228e-19	103.0	COG3420@1|root,COG3420@2|Bacteria,1WNFU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11
SRR25158456_k127_2673788_3	1239415.CM001837_gene2106	3.447e-35	142.0	COG2755@1|root,COG2755@2|Bacteria,4NMQM@976|Bacteroidetes,1I1P5@117743|Flavobacteriia,37FJJ@326319|Dokdonia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2682788_0	515635.Dtur_1563	1.737e-145	469.0	COG0495@1|root,COG0495@2|Bacteria	2|Bacteria	J	leucyl-tRNA aminoacylation	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158456_k127_2682788_1	234267.Acid_3219	4.078e-86	312.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2682788_3	696281.Desru_3269	7.695e-43	160.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,2626H@186807|Peptococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158456_k127_2682788_2	204669.Acid345_2223	2.588e-44	173.0	COG0629@1|root,COG0629@2|Bacteria,3Y4D2@57723|Acidobacteria,2JJ18@204432|Acidobacteriia	204432|Acidobacteriia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158456_k127_2682788_4	903818.KI912268_gene2181	4.961e-33	144.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_2686676_2	1416759.AYMR01000007_gene934	2.529e-13	74.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158456_k127_2686676_3	479434.Sthe_1389	1.224e-07	64.0	COG1807@1|root,COG1807@2|Bacteria,2G991@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2686676_1	635013.TherJR_1549	6.382e-80	287.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,260TU@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158456_k127_2686676_0	316067.Geob_1382	2.263e-100	361.0	2EWA0@1|root,33PNR@2|Bacteria,1NSPR@1224|Proteobacteria,42YN1@68525|delta/epsilon subdivisions,2WTJI@28221|Deltaproteobacteria,43U3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2695351_2	948106.AWZT01000019_gene4001	2.448e-20	96.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,2VTDF@28216|Betaproteobacteria,1K4TZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158456_k127_2695351_0	1128421.JAGA01000002_gene335	2.002e-141	463.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158456_k127_2695351_1	234267.Acid_3577	3.824e-141	468.0	COG0249@1|root,COG0249@2|Bacteria,3Y48T@57723|Acidobacteria	57723|Acidobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
SRR25158456_k127_2701165_8	1379698.RBG1_1C00001G1895	2.708e-25	123.0	COG0438@1|root,COG0438@2|Bacteria,2NQAY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_2701165_15	1192034.CAP_0031	7.372e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria,2Z3K8@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_2701165_1	1121377.KB906417_gene3827	7.682e-72	274.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_2701165_18	1348338.ADILRU_1120	9.064e-05	54.0	COG2456@1|root,COG2456@2|Bacteria,2GQTD@201174|Actinobacteria,4FQ3J@85023|Microbacteriaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
SRR25158456_k127_2701165_3	756272.Plabr_1771	5.172e-56	216.0	COG1215@1|root,COG1215@2|Bacteria,2J52E@203682|Planctomycetes	203682|Planctomycetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2701165_7	926550.CLDAP_10380	5.581e-43	172.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_2701165_9	555778.Hneap_0235	4.885e-22	106.0	COG0500@1|root,COG2226@2|Bacteria,1R7IA@1224|Proteobacteria,1SIK7@1236|Gammaproteobacteria,1X1DV@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158456_k127_2701165_2	251229.Chro_0821	3.731e-57	222.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_trans_4_5,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158456_k127_2701165_6	103690.17129902	1.819e-47	194.0	COG0463@1|root,COG4627@1|root,COG0463@2|Bacteria,COG4627@2|Bacteria,1GQ4G@1117|Cyanobacteria,1HN6Q@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
SRR25158456_k127_2701165_0	243231.GSU3021	1.587e-134	459.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42N6P@68525|delta/epsilon subdivisions,2WJVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
SRR25158456_k127_2701165_14	710421.Mycch_1280	5.16e-06	59.0	COG2244@1|root,COG2244@2|Bacteria,2HQKS@201174|Actinobacteria,237HG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158456_k127_2701165_4	748247.AZKH_0358	8.573e-51	188.0	COG0110@1|root,COG0110@2|Bacteria,1MZ7U@1224|Proteobacteria,2WF5U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158456_k127_2701165_12	512565.AMIS_4260	1.164e-07	63.0	COG1012@1|root,COG1012@2|Bacteria,2I9Y2@201174|Actinobacteria,4D9W6@85008|Micromonosporales	201174|Actinobacteria	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
SRR25158456_k127_2701165_5	382245.ASA_0155	5.263e-49	190.0	COG1541@1|root,COG1541@2|Bacteria,1NR5G@1224|Proteobacteria,1RRCG@1236|Gammaproteobacteria,1Y554@135624|Aeromonadales	135624|Aeromonadales	H	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
SRR25158456_k127_2701165_13	1122994.AUFR01000004_gene678	1.381e-07	63.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4DVBT@85009|Propionibacteriales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158456_k127_2701165_10	246196.MSMEI_0021	9.298e-15	86.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,233YJ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Peptide synthetase	-	-	-	ko:K16428,ko:K16429	ko01055,map01055	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_2701165_17	411459.RUMOBE_02437	2.869e-05	48.0	2EVBX@1|root,33NSE@2|Bacteria,1VKHC@1239|Firmicutes,24WCF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2706742_1	240015.ACP_1576	5.157e-22	108.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria,2JK6C@204432|Acidobacteriia	204432|Acidobacteriia	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158456_k127_2706742_2	644282.Deba_1250	4.823e-11	71.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158456_k127_2706742_0	204669.Acid345_0471	3.731e-69	241.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2708026_0	1173024.KI912153_gene216	0.0	1410.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158456_k127_2708026_4	1198114.AciX9_2411	2.41e-12	72.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158456_k127_2708026_1	204669.Acid345_1498	2.492e-75	265.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158456_k127_2708026_3	634497.HAH_5051	2.89e-25	117.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158456_k127_2708026_2	1267534.KB906756_gene711	9.864e-61	222.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158456_k127_2708840_3	1121920.AUAU01000002_gene1987	2.029e-61	215.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158456_k127_2708840_5	1333507.AUTQ01000085_gene1735	9.51e-43	173.0	2C8CD@1|root,2Z9AD@2|Bacteria,1N17D@1224|Proteobacteria,1RRIP@1236|Gammaproteobacteria,2PZK5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2708840_0	1089548.KI783301_gene190	2.117e-203	648.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,3WFDZ@539002|Bacillales incertae sedis	91061|Bacilli	C	Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158456_k127_2708840_6	234267.Acid_0699	4.948e-17	92.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158456_k127_2708840_4	589865.DaAHT2_2314	3.187e-59	214.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158456_k127_2708840_1	1125863.JAFN01000001_gene3451	8.169e-82	291.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
SRR25158456_k127_2708840_2	266117.Rxyl_0109	1.267e-73	255.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria	201174|Actinobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158456_k127_2735684_1	671143.DAMO_0253	3.706e-24	114.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
SRR25158456_k127_2735684_4	235985.BBPN01000011_gene4187	4.267e-09	69.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
SRR25158456_k127_2735684_2	1121927.GOHSU_12_01470	3.501e-16	93.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4GAN9@85026|Gordoniaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	wbbL	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	iNJ661.Rv3265c	Glyco_tranf_2_3,Glycos_transf_2
SRR25158456_k127_2735684_0	1283300.ATXB01000001_gene2336	1.42e-94	325.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1XF3R@135618|Methylococcales	135618|Methylococcales	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158456_k127_2735684_3	593750.Metfor_0743	1.082e-14	88.0	COG1520@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02538@1|root,arCOG06792@1|root,arCOG09475@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,arCOG06792@2157|Archaea,arCOG09475@2157|Archaea,2Y7Q0@28890|Euryarchaeota,2NAJS@224756|Methanomicrobia	28890|Euryarchaeota	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_3
SRR25158456_k127_274015_5	272134.KB731324_gene6611	2.536e-60	238.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
SRR25158456_k127_274015_0	234267.Acid_1490	3.359e-156	514.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158456_k127_274015_4	1267535.KB906767_gene1253	6.905e-80	274.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158456_k127_274015_8	1123250.KB908445_gene11	7.282e-32	128.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H4QP@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158456_k127_274015_2	555079.Toce_0711	1.532e-103	348.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_274015_1	240015.ACP_1006	3.623e-154	496.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1,4.4.1.2,4.4.1.8	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00609	R00782,R01001,R01283,R01286,R02408,R04941	RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158456_k127_274015_6	118173.KB235910_gene4949	9.441e-46	173.0	28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria,1HEPR@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_274015_7	1382359.JIAL01000001_gene2791	1.227e-39	155.0	COG0344@1|root,COG0344@2|Bacteria,3Y51D@57723|Acidobacteria,2JJFC@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158456_k127_274015_3	1267535.KB906767_gene1336	1.352e-84	302.0	COG0240@1|root,COG0240@2|Bacteria,3Y3ZH@57723|Acidobacteria,2JINS@204432|Acidobacteriia	204432|Acidobacteriia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158456_k127_274015_9	886293.Sinac_1397	2.444e-29	136.0	COG4485@1|root,COG4485@2|Bacteria,2J25S@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2740433_2	1472716.KBK24_0104220	2.348e-86	295.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2WFU5@28216|Betaproteobacteria,1KI63@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158456_k127_2740433_8	1123277.KB893174_gene5995	9.916e-10	68.0	29XWU@1|root,30JP9@2|Bacteria,4NNWG@976|Bacteroidetes,47PSI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2740433_3	925409.KI911562_gene1382	5.355e-74	263.0	COG2367@1|root,COG2367@2|Bacteria,4PMKC@976|Bacteroidetes,1J006@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158456_k127_2740433_7	1445613.JALM01000074_gene6748	6.756e-24	109.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4E3QY@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_2740433_9	861455.HMPREF9184_00072	0.0002746	48.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Haemagg_act,RHS_repeat
SRR25158456_k127_2740433_0	247490.KSU1_D0507	0.0	1799.0	COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2740433_1	247490.KSU1_D0506	1.569e-141	477.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR25158456_k127_2740433_6	395495.Lcho_2627	3.757e-31	130.0	COG1999@1|root,COG1999@2|Bacteria,1RF8N@1224|Proteobacteria	1224|Proteobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158456_k127_2740433_5	247490.KSU1_D0505	1.38e-42	182.0	COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
SRR25158456_k127_2740433_4	247490.KSU1_D0504	2.075e-61	244.0	COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
SRR25158456_k127_2740826_0	555079.Toce_1476	1.1e-118	402.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,42FDT@68295|Thermoanaerobacterales	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158456_k127_2740826_2	1122185.N792_05815	1.442e-50	184.0	2B2WH@1|root,31VH2@2|Bacteria,1QCMM@1224|Proteobacteria,1T8D0@1236|Gammaproteobacteria,1XAGE@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2740826_1	1121015.N789_06345	3.387e-106	372.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158456_k127_2740826_3	1246995.AFR_22910	6.079e-05	55.0	COG1396@1|root,COG1396@2|Bacteria,2GNTQ@201174|Actinobacteria,4DDA1@85008|Micromonosporales	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158456_k127_2741056_0	1121920.AUAU01000008_gene1537	1.108e-144	464.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158456_k127_2741056_2	710685.MycrhN_3796	2.858e-25	116.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,232W5@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158456_k127_2741056_1	1382306.JNIM01000001_gene3093	1.775e-131	438.0	COG0318@1|root,COG0318@2|Bacteria,2G5K4@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158456_k127_2741056_3	990285.RGCCGE502_25053	8.404e-10	72.0	COG1309@1|root,COG1309@2|Bacteria,1RDE7@1224|Proteobacteria,2UAIU@28211|Alphaproteobacteria,4BM7J@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158456_k127_2741113_0	883126.HMPREF9710_00104	2.873e-215	714.0	COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2VKWR@28216|Betaproteobacteria,476VV@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_2741113_7	1040989.AWZU01000001_gene5816	4.062e-103	352.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,3JUPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158456_k127_2741113_24	342610.Patl_0389	3.002e-19	98.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,2Q0FD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158456_k127_2741113_19	1562701.BBOF01000014_gene579	1.35e-37	149.0	COG5654@1|root,COG5654@2|Bacteria,1N6P3@1224|Proteobacteria,2VSGY@28216|Betaproteobacteria,1KFU4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158456_k127_2741113_27	1286631.X805_08080	2.831e-14	87.0	COG5642@1|root,COG5642@2|Bacteria,1RJWF@1224|Proteobacteria,2VTQA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
SRR25158456_k127_2741113_2	1047013.AQSP01000126_gene2740	8.764e-156	518.0	COG2866@1|root,COG2866@2|Bacteria,2NQNH@2323|unclassified Bacteria	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
SRR25158456_k127_2741113_11	670487.Ocepr_0886	3.679e-74	271.0	COG0737@1|root,COG0737@2|Bacteria,1WI46@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158456_k127_2741113_28	1469607.KK073769_gene5451	3.266e-11	66.0	COG2402@1|root,COG2402@2|Bacteria,1G6UZ@1117|Cyanobacteria,1HPSM@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158456_k127_2741113_14	1125863.JAFN01000001_gene3405	2.088e-63	235.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158456_k127_2741113_3	574087.Acear_0898	5.883e-118	394.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3WB9X@53433|Halanaerobiales	186801|Clostridia	F	PFAM Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158456_k127_2741113_1	1449126.JQKL01000035_gene2186	1.083e-206	658.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,268AK@186813|unclassified Clostridiales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158456_k127_2741113_9	867845.KI911784_gene1260	1.233e-77	280.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
SRR25158456_k127_2741113_15	903818.KI912268_gene1040	1.878e-59	221.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DUF4388,DnaJ
SRR25158456_k127_2741113_12	452637.Oter_1692	3.335e-66	244.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia,3K9Y4@414999|Opitutae	2|Bacteria	S	PFAM Pyrrolo-quinoline quinone	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_2,PQQ_3,Pkinase
SRR25158456_k127_2741113_23	598659.NAMH_0789	1.374e-21	109.0	COG0319@1|root,COG0319@2|Bacteria,1Q9G0@1224|Proteobacteria,42SJD@68525|delta/epsilon subdivisions,2YPJA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158456_k127_2741113_6	1499967.BAYZ01000057_gene4687	9.365e-105	349.0	COG1702@1|root,COG1702@2|Bacteria,2NNZF@2323|unclassified Bacteria	2|Bacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158456_k127_2741113_22	867903.ThesuDRAFT_00317	1.408e-23	110.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WCMZ@538999|Clostridiales incertae sedis	186801|Clostridia	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158456_k127_2741113_16	648996.Theam_0894	1.431e-52	202.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G3MD@200783|Aquificae	200783|Aquificae	J	tRNA nucleotidyltransferase poly(A) polymerase	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
SRR25158456_k127_2741113_30	555793.WSK_0130	3.4e-05	54.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,2KCTA@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_2741113_20	1125863.JAFN01000001_gene3329	2.198e-37	156.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
SRR25158456_k127_2741113_21	1392498.JQLH01000001_gene3171	5.016e-29	124.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I4A2@117743|Flavobacteriia,2PISF@252356|Maribacter	976|Bacteroidetes	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158456_k127_2741113_26	357808.RoseRS_2140	7.026e-15	86.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158456_k127_2741113_17	1306174.JODP01000013_gene7594	1.161e-42	176.0	COG1246@1|root,COG1246@2|Bacteria,2IGUU@201174|Actinobacteria	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158456_k127_2741113_13	118163.Ple7327_1459	1.62e-64	231.0	COG1611@1|root,COG1611@2|Bacteria,1G0YF@1117|Cyanobacteria	1117|Cyanobacteria	S	lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158456_k127_2741113_4	1382356.JQMP01000003_gene1909	4.569e-109	365.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158456_k127_2741113_10	234267.Acid_5444	1.634e-76	274.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158456_k127_2741113_5	1120972.AUMH01000003_gene2985	1.979e-105	348.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,279JQ@186823|Alicyclobacillaceae	91061|Bacilli	I	Coenzyme A transferase	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158456_k127_2741113_8	1121920.AUAU01000004_gene710	7.324e-92	319.0	COG2057@1|root,COG2057@2|Bacteria,3Y3EC@57723|Acidobacteria	57723|Acidobacteria	I	Coenzyme A transferase	-	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158456_k127_2741113_18	502025.Hoch_4942	2.001e-41	175.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,431QP@68525|delta/epsilon subdivisions,2WWXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2741113_31	208444.JNYY01000005_gene6184	0.0008025	51.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,2GNQ9@201174|Actinobacteria,4E7UB@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_31,TPR_12,TPR_4
SRR25158456_k127_2741113_29	742738.HMPREF9460_00387	5.543e-06	54.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_2741274_0	1121920.AUAU01000007_gene536	1.745e-148	480.0	COG0466@1|root,COG0466@2|Bacteria,3Y2QB@57723|Acidobacteria	57723|Acidobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158456_k127_2741274_2	1254432.SCE1572_22910	2.133e-51	186.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2YVAV@29|Myxococcales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158456_k127_2741274_3	1121930.AQXG01000014_gene382	2.932e-16	90.0	COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,1ISJK@117747|Sphingobacteriia	976|Bacteroidetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158456_k127_2741274_1	330214.NIDE3222	2.438e-70	249.0	COG0123@1|root,COG0123@2|Bacteria,3J0P2@40117|Nitrospirae	40117|Nitrospirae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158456_k127_2746592_2	1384054.N790_02540	2.85e-30	139.0	COG0457@1|root,COG0457@2|Bacteria,1QRIQ@1224|Proteobacteria,1T90E@1236|Gammaproteobacteria,1XBHE@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158456_k127_2746592_1	1237149.C900_01929	8.009e-215	672.0	COG3425@1|root,COG3425@2|Bacteria,4NGCA@976|Bacteroidetes,47WE0@768503|Cytophagia	976|Bacteroidetes	I	Hydroxymethylglutaryl-coenzyme A synthase N terminal	-	-	2.3.3.10	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
SRR25158456_k127_2746592_0	1296416.JACB01000039_gene1288	0.0	1674.0	COG1028@1|root,COG3321@1|root,COG4221@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia,2YGKF@290174|Aquimarina	976|Bacteroidetes	IQ	PKS_DH	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_2757219_0	485913.Krac_10454	9.302e-101	366.0	COG1672@1|root,COG2909@1|root,COG3591@1|root,COG1672@2|Bacteria,COG2909@2|Bacteria,COG3591@2|Bacteria,2G8QK@200795|Chloroflexi	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,Abhydrolase_1,DUF234,GerE,Trans_reg_C,Trypsin_2
SRR25158456_k127_2764156_2	324602.Caur_3493	4.975e-88	302.0	COG0673@1|root,COG0673@2|Bacteria,2G6V1@200795|Chloroflexi,375S4@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158456_k127_2764156_7	1219045.BV98_003232	1.861e-10	66.0	COG2207@1|root,COG2207@2|Bacteria,1PDUZ@1224|Proteobacteria,2UKB4@28211|Alphaproteobacteria,2K52J@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158456_k127_2764156_0	1007103.AFHW01000001_gene4982	1.079e-214	696.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,26RHB@186822|Paenibacillaceae	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158456_k127_2764156_5	880072.Desac_2292	2.771e-37	145.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MQJR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal_S15	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158456_k127_2764156_6	671143.DAMO_3051	3.655e-13	72.0	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158456_k127_2764156_3	234267.Acid_6299	4.333e-63	229.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
SRR25158456_k127_2764156_4	234267.Acid_7833	2.83e-55	203.0	COG1309@1|root,COG1309@2|Bacteria,3Y4QT@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158456_k127_2764156_1	204669.Acid345_0624	1.769e-112	374.0	COG1090@1|root,COG1090@2|Bacteria,3Y2PB@57723|Acidobacteria,2JI82@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158456_k127_2773572_0	1237149.C900_01919	3.068e-152	516.0	COG1028@1|root,COG2898@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2898@2|Bacteria,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,47XYI@768503|Cytophagia	976|Bacteroidetes	Q	PKS_KR	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase,DUF2156,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_2773572_1	1121007.AUML01000046_gene4054	1.328e-55	222.0	COG3321@1|root,COG4221@1|root,COG3321@2|Bacteria,COG4221@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia,2YGKF@290174|Aquimarina	976|Bacteroidetes	IQ	PKS_DH	-	-	-	-	-	-	-	-	-	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_2777592_0	903818.KI912269_gene52	8.806e-312	974.0	COG0058@1|root,COG0058@2|Bacteria,3Y47Y@57723|Acidobacteria	57723|Acidobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158456_k127_2777592_4	221288.JH992901_gene2489	1.675e-47	177.0	COG1670@1|root,COG1670@2|Bacteria,1G621@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158456_k127_2777592_7	234267.Acid_3898	2.339e-13	83.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158456_k127_2777592_6	682795.AciX8_3255	6.44e-18	100.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
SRR25158456_k127_2777592_1	1380393.JHVP01000003_gene1268	2.916e-120	424.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158456_k127_2777592_5	338966.Ppro_0645	9.983e-36	145.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158456_k127_2777592_2	82654.Pse7367_1114	1.276e-92	316.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1H8KG@1150|Oscillatoriales	1117|Cyanobacteria	M	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158456_k127_2777592_3	1385517.N800_02750	4.098e-79	280.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1X954@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158456_k127_2798421_0	358681.BBR47_27890	5.612e-315	1021.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae	91061|Bacilli	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K16124	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_2799262_2	1547437.LL06_21680	2.155e-70	254.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,43IIJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	MA20_01825	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158456_k127_2799262_0	1144275.COCOR_02243	1.466e-120	407.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158456_k127_2799262_4	388051.AUFE01000012_gene2886	9.921e-35	138.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
SRR25158456_k127_2799262_1	926560.KE387023_gene1159	1.694e-101	343.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158456_k127_2799262_5	1384054.N790_07985	2.93e-05	53.0	2AQ36@1|root,31F8E@2|Bacteria,1QCNP@1224|Proteobacteria,1T8E7@1236|Gammaproteobacteria,1XAIB@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_280850_9	398767.Glov_3107	6.32e-46	183.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158456_k127_280850_7	457415.HMPREF1006_02024	2.994e-63	239.0	COG1131@1|root,COG1131@2|Bacteria,3TAVU@508458|Synergistetes	508458|Synergistetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_280850_5	638302.HMPREF0908_0488	2.845e-71	251.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4H3CG@909932|Negativicutes	909932|Negativicutes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_280850_2	767817.Desgi_0885	9.371e-87	312.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia,261AQ@186807|Peptococcaceae	186801|Clostridia	U	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158456_k127_280850_16	1254432.SCE1572_26020	7.783e-07	59.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6Z3@28221|Deltaproteobacteria,2YWFG@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat
SRR25158456_k127_280850_14	258533.BN977_00372	1.33e-15	85.0	COG3710@1|root,COG3710@2|Bacteria,2HASC@201174|Actinobacteria,23FBP@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158456_k127_280850_18	1237149.C900_05862	0.0004075	52.0	COG1044@1|root,COG1044@2|Bacteria,4NSYI@976|Bacteroidetes,47RJE@768503|Cytophagia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_280850_13	926560.KE387023_gene3391	2.545e-19	101.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158456_k127_280850_0	246197.MXAN_1967	2.107e-136	462.0	COG1404@1|root,COG1404@2|Bacteria,1R5H7@1224|Proteobacteria,434MI@68525|delta/epsilon subdivisions,2WYZ0@28221|Deltaproteobacteria,2Z0YZ@29|Myxococcales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158456_k127_280850_17	425104.Ssed_3289	1.231e-05	59.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,1PFWN@1224|Proteobacteria,1SX3N@1236|Gammaproteobacteria,2QDG6@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,fn3
SRR25158456_k127_280850_12	1278073.MYSTI_05405	8.196e-23	108.0	2EFHE@1|root,3399Z@2|Bacteria	2|Bacteria	S	WXG100 protein secretion system (Wss), protein YukD	-	-	-	-	-	-	-	-	-	-	-	-	YukD
SRR25158456_k127_280850_1	1278073.MYSTI_05406	4.251e-125	414.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158456_k127_280850_10	1278073.MYSTI_05407	1.787e-36	150.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	JAB
SRR25158456_k127_280850_6	1278073.MYSTI_05408	2.561e-66	245.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
SRR25158456_k127_280850_8	1278073.MYSTI_05411	1.964e-53	192.0	COG5078@1|root,COG5078@2|Bacteria,1P62E@1224|Proteobacteria,432N1@68525|delta/epsilon subdivisions,2WY4Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Ubiquitin-conjugating	-	-	-	-	-	-	-	-	-	-	-	-	UQ_con
SRR25158456_k127_280850_4	1396418.BATQ01000007_gene1447	3.066e-74	267.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
SRR25158456_k127_280850_3	639030.JHVA01000001_gene1971	3.071e-78	269.0	COG0748@1|root,COG0748@2|Bacteria,3Y2Q3@57723|Acidobacteria,2JMJG@204432|Acidobacteriia	204432|Acidobacteriia	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Pyrid_oxidase_2
SRR25158456_k127_2809793_2	1123367.C666_08395	6.427e-33	133.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,2KWNA@206389|Rhodocyclales	206389|Rhodocyclales	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
SRR25158456_k127_2809793_0	1179773.BN6_71620	4.227e-120	395.0	COG2220@1|root,COG2220@2|Bacteria,2GNXJ@201174|Actinobacteria,4DYA7@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase of beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158456_k127_2809793_3	1117318.PRUB_19012	3.943e-16	89.0	COG3595@1|root,COG3595@2|Bacteria,1RI1P@1224|Proteobacteria,1RRZW@1236|Gammaproteobacteria,2Q0AP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158456_k127_2809793_1	1519464.HY22_02720	2.056e-47	181.0	COG0546@1|root,COG0546@2|Bacteria,1FDVN@1090|Chlorobi	1090|Chlorobi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158456_k127_2824514_2	1158610.UC3_01798	9.832e-64	232.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,4HD67@91061|Bacilli,4B229@81852|Enterococcaceae	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_2824514_11	390235.PputW619_2280	5.592e-08	58.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1QZPU@1224|Proteobacteria	1224|Proteobacteria	L	AAA domain	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_11,AAA_12
SRR25158456_k127_2824514_12	1242864.D187_010224	3.356e-07	57.0	COG3145@1|root,COG3145@2|Bacteria,1RDBK@1224|Proteobacteria	1224|Proteobacteria	L	Pfam 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRR25158456_k127_2824514_0	861299.J421_1123	1.34e-203	666.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,fn3
SRR25158456_k127_2824514_7	1183438.GKIL_3263	1.248e-36	160.0	COG1470@1|root,COG3391@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,VCBS
SRR25158456_k127_2824514_8	1128421.JAGA01000003_gene2958	1.58e-31	131.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158456_k127_2824514_3	700598.Niako_1577	4.567e-60	220.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,1IQI9@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158456_k127_2824514_4	1128421.JAGA01000002_gene1329	2.149e-59	232.0	COG0642@1|root,COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3852@2|Bacteria,2NQNP@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_2824514_5	1121946.AUAX01000039_gene5751	1.264e-43	186.0	COG3227@1|root,COG3227@2|Bacteria,2GN0P@201174|Actinobacteria,4D9AK@85008|Micromonosporales	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M36
SRR25158456_k127_2824514_10	502025.Hoch_5330	1.33e-17	100.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria,2YUCY@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,Peptidase_S8
SRR25158456_k127_2824514_13	1449355.JQNR01000004_gene1703	3.558e-06	60.0	COG0457@1|root,COG1672@1|root,COG3629@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG3629@2|Bacteria,2H1NS@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,NB-ARC,TPR_12,TPR_7,Trans_reg_C
SRR25158456_k127_2824514_6	1280001.BAOA01000232_gene4320	1.558e-41	166.0	arCOG09511@1|root,2Z9DH@2|Bacteria,1MXRV@1224|Proteobacteria,1SEJ5@1236|Gammaproteobacteria,1XZ1Y@135623|Vibrionales	135623|Vibrionales	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
SRR25158456_k127_2824514_9	671143.DAMO_1580	5.306e-21	96.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_2824514_1	1173027.Mic7113_2540	1.044e-80	273.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158456_k127_28331_0	114615.BRADO6364	2.483e-81	293.0	COG1680@1|root,COG1680@2|Bacteria,1PDR2@1224|Proteobacteria,2U487@28211|Alphaproteobacteria,3JXAT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_28331_2	234267.Acid_1101	1.899e-53	211.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_28331_5	1382304.JNIL01000001_gene1912	1.301e-31	141.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,2787M@186823|Alicyclobacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRR25158456_k127_28331_6	1163409.UUA_01574	1.896e-10	66.0	COG2207@1|root,COG2207@2|Bacteria,1N8ZK@1224|Proteobacteria,1T6Z9@1236|Gammaproteobacteria,1X8G8@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158456_k127_28331_1	1458357.BG58_06375	1.601e-66	233.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2W1Y0@28216|Betaproteobacteria,1KFM5@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158456_k127_28331_3	1249997.JHZW01000002_gene362	8.329e-50	185.0	COG1794@1|root,COG1794@2|Bacteria,4NM9B@976|Bacteroidetes,1I13P@117743|Flavobacteriia,2PHKE@252356|Maribacter	976|Bacteroidetes	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158456_k127_28331_4	627192.SLG_13640	1.529e-46	188.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2U5VQ@28211|Alphaproteobacteria,2KD3T@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158456_k127_2838075_0	316273.XCV2155	1.109e-253	816.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QU1S@1224|Proteobacteria,1T1MB@1236|Gammaproteobacteria,1X3A7@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SRR25158456_k127_2838075_3	1449076.JOOE01000001_gene2448	2.425e-97	329.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VFDU@28211|Alphaproteobacteria,2K48Y@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158456_k127_2838075_7	1122603.ATVI01000006_gene747	4.53e-56	201.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5U@1224|Proteobacteria,1SAZE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD,HDOD
SRR25158456_k127_2838075_11	1297570.MESS4_640063	6.912e-30	131.0	2CZ4M@1|root,32T5I@2|Bacteria,1N344@1224|Proteobacteria,2UDM4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2838075_5	1123261.AXDW01000004_gene2959	4.934e-59	207.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,1STUQ@1236|Gammaproteobacteria,1XBHR@135614|Xanthomonadales	135614|Xanthomonadales	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158456_k127_2838075_8	42256.RradSPS_2282	2.113e-49	185.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_2838075_1	378806.STAUR_3171	5.892e-250	790.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,437F6@68525|delta/epsilon subdivisions,2X2MS@28221|Deltaproteobacteria,2YTV3@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158456_k127_2838075_13	1123368.AUIS01000035_gene84	7.835e-15	85.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,1RMS4@1236|Gammaproteobacteria,2NC2T@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Chitin synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2838075_12	279714.FuraDRAFT_3426	7.086e-28	124.0	2EM58@1|root,33EUJ@2|Bacteria,1NKF3@1224|Proteobacteria,2W0E1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2838075_14	1449049.JONW01000005_gene1937	1.302e-12	80.0	COG1216@1|root,COG1216@2|Bacteria,1R6SJ@1224|Proteobacteria,2U47V@28211|Alphaproteobacteria,2KFG0@204458|Caulobacterales	204458|Caulobacterales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_2838075_9	187272.Mlg_2356	2.569e-41	176.0	2DTDB@1|root,33QST@2|Bacteria,1NR96@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2838075_4	1121861.KB899930_gene178	1.613e-77	292.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2JQAX@204441|Rhodospirillales	204441|Rhodospirillales	V	ABC-type multidrug transport system, ATPase and permease	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_2838075_6	1522072.IL54_3706	2.126e-57	218.0	COG1301@1|root,COG1301@2|Bacteria,1MVID@1224|Proteobacteria,2TUR0@28211|Alphaproteobacteria,2K09V@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
SRR25158456_k127_2838075_10	861299.J421_4116	3.256e-37	147.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158456_k127_2838075_2	234267.Acid_2611	3.899e-192	623.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_2839852_1	1283300.ATXB01000002_gene2755	2.217e-224	762.0	COG2351@1|root,COG2351@2|Bacteria,1QWX0@1224|Proteobacteria,1T4J1@1236|Gammaproteobacteria,1XG68@135618|Methylococcales	135618|Methylococcales	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2839852_0	448385.sce8560	0.0	1863.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria,2YYWN@29|Myxococcales	28221|Deltaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
SRR25158456_k127_2839852_2	1439940.BAY1663_01584	5.098e-22	102.0	2B2CQ@1|root,31UX4@2|Bacteria,1RBM3@1224|Proteobacteria,1SBUB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2842584_4	592316.Pat9b_2117	0.0007499	52.0	COG5492@1|root,COG5492@2|Bacteria,1QI2T@1224|Proteobacteria,1RQ6J@1236|Gammaproteobacteria,3W0P7@53335|Pantoea	1236|Gammaproteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Ig_3,Phage_tail_2
SRR25158456_k127_2842584_3	1236908.wNo_05320	3.119e-46	173.0	COG3757@1|root,COG3757@2|Bacteria,1R57X@1224|Proteobacteria,2U1NJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	M1 (1,4-beta-N-acetylmuramidase)	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
SRR25158456_k127_2842584_1	935557.ATYB01000007_gene1247	1.095e-49	187.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSTD@28211|Alphaproteobacteria,4BJGB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158456_k127_2842584_0	1379270.AUXF01000002_gene1216	1.961e-57	220.0	COG4603@1|root,COG4603@2|Bacteria,1ZTGR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158456_k127_2842584_2	446470.Snas_1353	8.399e-48	180.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4EXVX@85014|Glycomycetales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158456_k127_2859499_15	1458427.BAWN01000017_gene1127	7.361e-43	160.0	COG1487@1|root,COG1487@2|Bacteria,1N9J5@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_2859499_18	1458427.BAWN01000017_gene1128	1.955e-20	100.0	COG5450@1|root,COG5450@2|Bacteria,1Q0B5@1224|Proteobacteria,2W539@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158456_k127_2859499_5	395492.Rleg2_1811	2.05e-149	481.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2TU9J@28211|Alphaproteobacteria,4B9F0@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158456_k127_2859499_2	296591.Bpro_0977	4.598e-197	626.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,2W0X0@28216|Betaproteobacteria,4AJVZ@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	ko:K08169	-	-	-	-	ko00000,ko02000	2.A.1.3.17	-	-	MFS_1,MFS_3
SRR25158456_k127_2859499_8	1123368.AUIS01000033_gene1370	2.917e-100	332.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria	1224|Proteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_2859499_17	396588.Tgr7_2556	2.672e-37	147.0	COG1309@1|root,COG1309@2|Bacteria,1RBV0@1224|Proteobacteria	1224|Proteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158456_k127_2859499_19	3659.XP_004172054.1	0.0001062	51.0	28KYQ@1|root,2QTFH@2759|Eukaryota,37JIR@33090|Viridiplantae,3GATE@35493|Streptophyta,4JU14@91835|fabids	35493|Streptophyta	S	Pollen proteins Ole e I like	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009664,GO:0009987,GO:0016043,GO:0030312,GO:0044464,GO:0045229,GO:0071554,GO:0071555,GO:0071669,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Pollen_Ole_e_I
SRR25158456_k127_2859499_12	398767.Glov_2429	9.417e-53	209.0	COG5397@1|root,COG5397@2|Bacteria,1PJM3@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
SRR25158456_k127_2859499_16	926554.KI912676_gene586	5.704e-39	153.0	COG4339@1|root,COG4339@2|Bacteria,1WMR8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2859499_10	1535422.ND16A_0896	1.999e-76	271.0	COG0845@1|root,COG0845@2|Bacteria,1R50D@1224|Proteobacteria,1RRYM@1236|Gammaproteobacteria,2Q5TY@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_2859499_9	1535422.ND16A_1927	6.884e-94	323.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1SYJN@1236|Gammaproteobacteria,2Q7VX@267889|Colwelliaceae	1236|Gammaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2859499_6	28229.ND2E_0301	9.169e-112	391.0	COG0577@1|root,COG0577@2|Bacteria,1R880@1224|Proteobacteria,1S0ZI@1236|Gammaproteobacteria,2Q681@267889|Colwelliaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_2859499_7	1117318.PRUB_18795	1.657e-111	370.0	COG2175@1|root,COG2175@2|Bacteria,1MWQ6@1224|Proteobacteria,1RP8I@1236|Gammaproteobacteria,2Q0MN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
SRR25158456_k127_2859499_13	263358.VAB18032_22165	9.481e-46	186.0	COG3208@1|root,COG3208@2|Bacteria,2GMY8@201174|Actinobacteria,4DCY3@85008|Micromonosporales	201174|Actinobacteria	Q	thioesterase involved in non-ribosomal peptide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Thioesterase
SRR25158456_k127_2859499_3	377629.TERTU_2330	5.489e-195	623.0	COG2220@1|root,COG2220@2|Bacteria,1R4BX@1224|Proteobacteria,1RS4A@1236|Gammaproteobacteria,2PPGR@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
SRR25158456_k127_2859499_1	84531.JMTZ01000033_gene258	1.421e-222	718.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,1X80Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158456_k127_2859499_4	1117318.PRUB_24140	2.548e-155	509.0	COG4615@1|root,COG4615@2|Bacteria,1MVIC@1224|Proteobacteria,1RMYK@1236|Gammaproteobacteria,2Q3Y9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	PQ	ATPase and permease components	-	-	-	ko:K06160	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.113.2	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_2859499_11	999541.bgla_2g16380	7.789e-75	268.0	COG2850@1|root,COG2850@2|Bacteria,1MUAC@1224|Proteobacteria,2WFE3@28216|Betaproteobacteria,1KI14@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Cupin-like domain	-	-	-	ko:K19219	-	-	-	-	ko00000,ko03036	-	-	-	Cupin_8
SRR25158456_k127_2859499_0	179408.Osc7112_5184	2.029e-234	756.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H7F4@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,TPR_1,TPR_8,Thioesterase
SRR25158456_k127_2868724_0	709032.Sulku_0587	1.518e-106	362.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2YTAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158456_k127_2868724_4	1163617.SCD_n02982	4.06e-48	195.0	COG0438@1|root,COG0438@2|Bacteria,1R8GY@1224|Proteobacteria,2VX9K@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158456_k127_2868724_6	1382230.ASAP_0706	1.31e-21	105.0	COG3306@1|root,COG3306@2|Bacteria,1NF1G@1224|Proteobacteria,2UK2D@28211|Alphaproteobacteria,2JY7B@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase family 25 (LPS biosynthesis protein)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_25
SRR25158456_k127_2868724_8	886293.Sinac_3412	5.948e-10	72.0	COG0438@1|root,COG0438@2|Bacteria,2J3Q6@203682|Planctomycetes	203682|Planctomycetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2868724_1	709032.Sulku_1089	5.094e-98	347.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR25158456_k127_2868724_7	709032.Sulku_0588	9.872e-15	87.0	COG1794@1|root,COG1794@2|Bacteria	2|Bacteria	M	racemase activity, acting on amino acids and derivatives	mcyF	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158456_k127_2868724_3	497965.Cyan7822_0435	5.965e-77	266.0	28PS1@1|root,2ZCDP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2869171_5	65393.PCC7424_0863	7.141e-05	55.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,3KGI4@43988|Cyanothece	1117|Cyanobacteria	N	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
SRR25158456_k127_2869171_2	272569.rrnB0083	2.477e-20	100.0	arCOG03085@1|root,arCOG03085@2157|Archaea,2XWPM@28890|Euryarchaeota,23VFX@183963|Halobacteria	183963|Halobacteria	T	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
SRR25158456_k127_2869171_1	398525.KB900701_gene378	1.014e-29	138.0	COG0457@1|root,COG0457@2|Bacteria,1QDET@1224|Proteobacteria,2V6ZS@28211|Alphaproteobacteria,3K3ZX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2869171_4	7955.ENSDARP00000066933	1.235e-05	57.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,4985B@7742|Vertebrata,49SNB@7898|Actinopterygii	33208|Metazoa	S	Inter-alpha-trypsin inhibitor heavy chain	ITIH5	-	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA,VWA_3
SRR25158456_k127_2869171_3	502025.Hoch_2651	1.799e-15	82.0	COG0477@1|root,COG2814@2|Bacteria,1NH45@1224|Proteobacteria,42VV0@68525|delta/epsilon subdivisions,2X6PC@28221|Deltaproteobacteria,2Z3C2@29|Myxococcales	28221|Deltaproteobacteria	EGP	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
SRR25158456_k127_2869171_0	391625.PPSIR1_23489	2.857e-77	275.0	COG1409@1|root,COG1409@2|Bacteria,1RK5B@1224|Proteobacteria,42SWF@68525|delta/epsilon subdivisions,2WPKV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158456_k127_2871833_0	240015.ACP_2445	1.059e-126	423.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158456_k127_2871833_2	500635.MITSMUL_04922	1.986e-87	311.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4H2CM@909932|Negativicutes	909932|Negativicutes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
SRR25158456_k127_2871833_1	1121346.KB899815_gene1901	4.973e-120	415.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158456_k127_2871833_5	1121920.AUAU01000013_gene1762	2.162e-23	101.0	COG0828@1|root,COG0828@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158456_k127_2871833_4	163908.KB235896_gene4482	2.654e-37	145.0	COG1487@1|root,COG1487@2|Bacteria,1GJPV@1117|Cyanobacteria,1HS9A@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158456_k127_2871833_6	1267534.KB906757_gene926	3.507e-17	96.0	COG0308@1|root,COG0308@2|Bacteria,3Y7E9@57723|Acidobacteria,2JMED@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158456_k127_2871833_3	316274.Haur_0823	3.116e-72	265.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi,376PV@32061|Chloroflexia	32061|Chloroflexia	F	PFAM phosphoribulokinase uridine kinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SRR25158456_k127_2872009_3	278963.ATWD01000002_gene489	9.587e-82	275.0	COG1028@1|root,COG1028@2|Bacteria,3Y3CD@57723|Acidobacteria,2JHIF@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158456_k127_2872009_0	861299.J421_5606	5.697e-192	608.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158456_k127_2872009_1	1442599.JAAN01000043_gene450	7.384e-181	575.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,1RP70@1236|Gammaproteobacteria,1X56Y@135614|Xanthomonadales	135614|Xanthomonadales	G	Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
SRR25158456_k127_2872009_2	1123276.KB893259_gene2540	1.456e-83	282.0	COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,47KAP@768503|Cytophagia	976|Bacteroidetes	G	Glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
SRR25158456_k127_2872952_3	1231392.OCGS_0963	4.873e-56	204.0	COG1637@1|root,COG1637@2|Bacteria,1Q97I@1224|Proteobacteria,2U1AD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	nuclease of the RecB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
SRR25158456_k127_2872952_6	558152.IQ37_10100	4.129e-05	48.0	2ABUY@1|root,311BS@2|Bacteria,4PG47@976|Bacteroidetes,1IGZX@117743|Flavobacteriia,3ZSMU@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2872952_0	338963.Pcar_2345	5.596e-156	505.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_2872952_1	56780.SYN_02714	3.557e-107	379.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MQRW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158456_k127_2872952_5	582744.Msip34_0188	1.165e-06	57.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,2KN1E@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
SRR25158456_k127_2872952_2	483219.LILAB_32760	3.824e-81	282.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
SRR25158456_k127_2873961_0	398767.Glov_1669	1.426e-131	429.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158456_k127_2873961_6	1278307.KB907040_gene1962	1.183e-11	70.0	COG1550@1|root,COG1550@2|Bacteria,1NGDU@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158456_k127_2873961_5	574087.Acear_1595	1.503e-15	83.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WAT9@53433|Halanaerobiales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158456_k127_2873961_1	518766.Rmar_0040	1.446e-97	329.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes	976|Bacteroidetes	J	Pfam Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158456_k127_2873961_2	1131269.AQVV01000014_gene208	1.034e-53	207.0	COG1949@1|root,COG1949@2|Bacteria	2|Bacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158456_k127_2873961_7	1394178.AWOO02000049_gene6169	0.000454	52.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4EGEN@85012|Streptosporangiales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158456_k127_2873961_4	768670.Calni_2090	1.088e-31	139.0	COG0790@1|root,COG0790@2|Bacteria,2GFZV@200930|Deferribacteres	200930|Deferribacteres	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SRR25158456_k127_2892891_8	290397.Adeh_3048	2.346e-42	157.0	COG2203@1|root,COG3576@1|root,COG2203@2|Bacteria,COG3576@2|Bacteria,1PP8V@1224|Proteobacteria	1224|Proteobacteria	T	flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF_2,Putative_PNPOx
SRR25158456_k127_2892891_15	1541065.JRFE01000009_gene4504	3.245e-21	94.0	COG1598@1|root,COG1598@2|Bacteria,1G97T@1117|Cyanobacteria,3VKM4@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158456_k127_2892891_0	1192034.CAP_0358	0.0	1178.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158456_k127_2892891_17	926550.CLDAP_07640	3.562e-14	82.0	COG2161@1|root,COG2161@2|Bacteria,2G9Q0@200795|Chloroflexi	200795|Chloroflexi	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_2892891_11	926550.CLDAP_07630	1.675e-30	124.0	COG4113@1|root,COG4113@2|Bacteria,2G8Z6@200795|Chloroflexi	200795|Chloroflexi	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_2892891_18	1500894.JQNN01000001_gene3116	9.519e-09	65.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VR6Y@28216|Betaproteobacteria,4732D@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	outer membrane protein W	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SRR25158456_k127_2892891_16	465541.ATCJ01000001_gene478	2.703e-14	84.0	COG3468@1|root,COG3468@2|Bacteria,2H6JR@201174|Actinobacteria	201174|Actinobacteria	MU	Cell surface	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158456_k127_2892891_19	243160.BMA1408	0.0002068	53.0	COG1622@1|root,COG1622@2|Bacteria,1NEC9@1224|Proteobacteria,2VWA0@28216|Betaproteobacteria,1K8PX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	cytochrome C oxidase	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1
SRR25158456_k127_2892891_9	237368.SCABRO_00880	3.438e-40	168.0	COG0535@1|root,COG0535@2|Bacteria,2IWZK@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158456_k127_2892891_3	1278073.MYSTI_05735	2.567e-83	296.0	COG0412@1|root,COG0412@2|Bacteria,1QRBY@1224|Proteobacteria,43E13@68525|delta/epsilon subdivisions,2WZE4@28221|Deltaproteobacteria,2Z1XS@29|Myxococcales	28221|Deltaproteobacteria	Q	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2892891_13	1278073.MYSTI_01475	1.738e-28	119.0	2BU8D@1|root,32PHV@2|Bacteria,1NANB@1224|Proteobacteria,433N8@68525|delta/epsilon subdivisions,2WXKZ@28221|Deltaproteobacteria,2Z2G5@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
SRR25158456_k127_2892891_5	660470.Theba_2513	8.324e-58	206.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	HTH_31,Pep_deformylase
SRR25158456_k127_2892891_7	670487.Ocepr_0388	1.847e-49	190.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_2892891_6	861299.J421_4066	9.998e-56	220.0	COG0515@1|root,COG0515@2|Bacteria,1ZTGA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158456_k127_2892891_10	375286.mma_1690	5.867e-37	149.0	COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,2VT83@28216|Betaproteobacteria,474J5@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
SRR25158456_k127_2892891_1	1242864.D187_006166	5.675e-268	839.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria,2YWG3@29|Myxococcales	28221|Deltaproteobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158456_k127_2892891_4	324925.Ppha_2430	3.006e-62	244.0	COG0455@1|root,COG5635@1|root,COG0455@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K02282,ko:K03321	-	-	-	-	ko00000,ko02000,ko02035,ko02044	2.A.53.3	-	-	CbiA,NACHT,Pentapeptide,WD40,Wzz
SRR25158456_k127_2892891_12	1408428.JNJP01000051_gene3814	1.737e-30	129.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2MB9P@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM Cyclic nucleotide-binding	fnr-1	-	-	ko:K01420,ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158456_k127_2892891_14	1192034.CAP_5238	7.082e-25	108.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_2892891_2	861299.J421_0743	1.144e-132	440.0	COG4623@1|root,COG4623@2|Bacteria	2|Bacteria	M	carbon-oxygen lyase activity, acting on polysaccharides	mltF	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
SRR25158456_k127_2899776_3	234267.Acid_6886	7.946e-34	136.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_2899776_6	1333523.L593_02375	1.482e-17	98.0	COG3291@1|root,arCOG03509@1|root,arCOG02546@2157|Archaea,arCOG03509@2157|Archaea,2Y7ZF@28890|Euryarchaeota,24143@183963|Halobacteria	183963|Halobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158456_k127_2899776_2	234267.Acid_3219	6.327e-74	280.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2899776_1	765912.Thimo_1337	2.87e-100	342.0	COG2909@1|root,COG2909@2|Bacteria,1R4DB@1224|Proteobacteria,1THR3@1236|Gammaproteobacteria,1X0D9@135613|Chromatiales	135613|Chromatiales	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2899776_0	1499967.BAYZ01000177_gene5721	1.099e-118	406.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,BTAD,Guanylate_cyc,Pkinase,SEFIR,TIR_2
SRR25158456_k127_29025_1	861299.J421_3038	6.76e-116	404.0	COG0308@1|root,COG0823@1|root,COG0308@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	VVA0929	-	3.4.11.2	ko:K01256,ko:K03641	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko02000	2.C.1.2	-	-	PD40,Peptidase_MA_2
SRR25158456_k127_29025_0	1166018.FAES_1629	8.034e-125	409.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
SRR25158456_k127_29025_2	945713.IALB_3010	0.0002673	53.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,Fibrinogen_C,PA,Peptidase_S8,cNMP_binding,fn3_5
SRR25158456_k127_2918511_8	1454004.AW11_00236	5.707e-24	102.0	COG1988@1|root,COG1988@2|Bacteria,1PCAC@1224|Proteobacteria,2WFID@28216|Betaproteobacteria,1KQSK@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158456_k127_2918511_10	5759.rna_EHI_169340-1	2.109e-18	98.0	2D6RI@1|root,2T2RS@2759|Eukaryota,3XC2S@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2918511_9	1192034.CAP_5101	5.488e-20	101.0	COG0500@1|root,COG2226@2|Bacteria,1N5QH@1224|Proteobacteria,438CN@68525|delta/epsilon subdivisions,2X1WJ@28221|Deltaproteobacteria,2YWJX@29|Myxococcales	28221|Deltaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158456_k127_2918511_5	1123489.AUAN01000002_gene896	2.65e-36	148.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4H1VQ@909932|Negativicutes	909932|Negativicutes	G	hopanoid biosynthesis associated protein HpnK	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
SRR25158456_k127_2918511_2	479431.Namu_4403	3.947e-65	242.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158456_k127_2918511_7	1193181.BN10_1030011	4.438e-30	127.0	COG2227@1|root,COG2227@2|Bacteria,2IJEF@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158456_k127_2918511_6	234267.Acid_7679	5.872e-31	138.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_2918511_0	234267.Acid_0040	2.847e-157	524.0	COG1960@1|root,COG1960@2|Bacteria,3Y2FM@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158456_k127_2918511_4	211114.JOEF01000023_gene5794	5.17e-58	210.0	COG0010@1|root,COG0010@2|Bacteria,2HG7A@201174|Actinobacteria,4EC0H@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR25158456_k127_2918511_1	204669.Acid345_0609	3.329e-110	365.0	COG1494@1|root,COG1494@2|Bacteria,3Y2XJ@57723|Acidobacteria,2JKWZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158456_k127_2918511_3	1122917.KB899662_gene2295	7.929e-64	237.0	COG0564@1|root,COG0564@2|Bacteria,1TSPG@1239|Firmicutes,4HBGS@91061|Bacilli,26R3Q@186822|Paenibacillaceae	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluA	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2,S4_2
SRR25158456_k127_2918511_11	93220.LV28_24150	5.629e-12	73.0	COG0457@1|root,COG0457@2|Bacteria	93220.LV28_24150|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2919308_0	1396418.BATQ01000179_gene3160	5.773e-152	505.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,46US9@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_2919308_2	1123276.KB893260_gene2577	5.825e-15	84.0	2AP2K@1|root,31E40@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2919308_1	861299.J421_2108	2.684e-74	262.0	COG0628@1|root,COG0628@2|Bacteria,1ZSY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158456_k127_2919308_3	1380393.JHVP01000001_gene2189	4.905e-11	70.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria,4EWRZ@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158456_k127_2923982_2	1382306.JNIM01000001_gene2045	1.328e-51	207.0	COG0745@1|root,COG0745@2|Bacteria,2G81R@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_2923982_3	1123256.KB907925_gene1227	1.195e-44	180.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,1X3FI@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR25158456_k127_2923982_4	1123504.JQKD01000006_gene1671	4.894e-32	130.0	2D4D1@1|root,32TGT@2|Bacteria,1NP2H@1224|Proteobacteria,2W4KG@28216|Betaproteobacteria,4AIEI@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2923982_6	1280953.HOC_14108	1.109e-14	77.0	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,2UB31@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
SRR25158456_k127_2923982_0	864051.BurJ1DRAFT_3475	1.901e-217	712.0	COG2333@1|root,COG4995@1|root,COG2333@2|Bacteria,COG4995@2|Bacteria,1RE10@1224|Proteobacteria	1224|Proteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_2923982_1	1267534.KB906754_gene2823	1.354e-184	602.0	COG2010@1|root,COG2010@2|Bacteria,3Y31J@57723|Acidobacteria,2JKC9@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2923982_5	1267005.KB911258_gene118	8.182e-20	106.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,2UJP4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
SRR25158456_k127_2939301_8	395965.Msil_2681	3.776e-23	103.0	COG4566@1|root,COG4566@2|Bacteria,1MZ8E@1224|Proteobacteria,2UBRR@28211|Alphaproteobacteria,3NCSK@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158456_k127_2939301_2	1225785.CM001983_gene2255	7.008e-109	363.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,2JDG0@204037|Dickeya	1236|Gammaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	fhlA	GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
SRR25158456_k127_2939301_3	215803.DB30_3761	8.029e-96	321.0	2DB9K@1|root,2Z7XA@2|Bacteria,1R4GI@1224|Proteobacteria,43877@68525|delta/epsilon subdivisions,2XA0I@28221|Deltaproteobacteria,2YW2F@29|Myxococcales	28221|Deltaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158456_k127_2939301_6	269799.Gmet_2627	6.981e-43	175.0	COG1073@1|root,COG1073@2|Bacteria,1R9V1@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DUF900
SRR25158456_k127_2939301_7	1254432.SCE1572_29395	3.204e-36	153.0	COG2312@1|root,COG2312@2|Bacteria,1NEZB@1224|Proteobacteria,433VP@68525|delta/epsilon subdivisions,2X3PC@28221|Deltaproteobacteria,2YWR8@29|Myxococcales	28221|Deltaproteobacteria	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg,Erythro_esteras
SRR25158456_k127_2939301_9	1185876.BN8_02019	2.295e-16	87.0	COG1073@1|root,COG1073@2|Bacteria,4NS0T@976|Bacteroidetes,47QGY@768503|Cytophagia	976|Bacteroidetes	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
SRR25158456_k127_2939301_1	1267534.KB906754_gene2823	2.028e-175	578.0	COG2010@1|root,COG2010@2|Bacteria,3Y31J@57723|Acidobacteria,2JKC9@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2939301_0	927677.ALVU02000001_gene2170	1.262e-202	647.0	COG2303@1|root,COG2303@2|Bacteria,1FZYZ@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158456_k127_2939301_10	658612.MD26_21050	0.0001701	54.0	COG2154@1|root,COG2154@2|Bacteria,1R1DV@1224|Proteobacteria	1224|Proteobacteria	H	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_2939301_4	765420.OSCT_0651	4.413e-61	229.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158456_k127_294015_0	1242864.D187_002505	3.51e-132	433.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,42P8U@68525|delta/epsilon subdivisions,2WTQE@28221|Deltaproteobacteria,2YZNT@29|Myxococcales	28221|Deltaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158456_k127_294015_1	316274.Haur_2706	3.496e-100	331.0	COG0861@1|root,COG0861@2|Bacteria,2GACS@200795|Chloroflexi,376V3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
SRR25158456_k127_294015_10	1173027.Mic7113_2666	6.428e-06	56.0	2DSZT@1|root,33I3H@2|Bacteria,1GADT@1117|Cyanobacteria,1HGKX@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_294015_7	1173263.Syn7502_00143	9.102e-36	139.0	COG2402@1|root,COG2402@2|Bacteria,1G7JM@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_294015_9	1047013.AQSP01000142_gene142	6.181e-07	61.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158456_k127_294015_6	1502852.FG94_03180	1.727e-39	163.0	COG4758@1|root,COG4758@2|Bacteria,1RFX6@1224|Proteobacteria,2WCSU@28216|Betaproteobacteria,4772Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_294015_5	1198452.Jab_1c25300	3.002e-50	201.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2W9CU@28216|Betaproteobacteria,4769K@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158456_k127_294015_2	204669.Acid345_3487	1.715e-80	274.0	COG3279@1|root,COG3279@2|Bacteria,3Y3B3@57723|Acidobacteria,2JP1W@204432|Acidobacteriia	204432|Acidobacteriia	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158456_k127_294015_3	36809.MAB_3055c	4.504e-55	208.0	COG3576@1|root,COG3576@2|Bacteria,2GP9M@201174|Actinobacteria,236AI@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158456_k127_294015_4	103733.JNYO01000068_gene4759	2.041e-51	185.0	COG0346@1|root,COG0346@2|Bacteria,2IHXI@201174|Actinobacteria,4E4PR@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158456_k127_294015_11	740709.A10D4_13426	0.0001415	48.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158456_k127_2940824_2	673862.BABL1_1000	3.831e-09	70.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS
SRR25158456_k127_2940824_1	706587.Desti_2374	7.067e-98	353.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MQ3Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	PFAM Type II IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158456_k127_2940824_0	1121405.dsmv_0772	2.737e-109	389.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MII7@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158456_k127_2943707_3	204669.Acid345_2293	2.237e-14	76.0	COG3301@1|root,COG3301@2|Bacteria,3Y506@57723|Acidobacteria,2JN1H@204432|Acidobacteriia	204432|Acidobacteriia	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158456_k127_2943707_1	1411123.JQNH01000001_gene3173	1.66e-100	336.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2U62M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158456_k127_2943707_0	204669.Acid345_2395	4.832e-107	376.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
SRR25158456_k127_2943707_2	633149.Bresu_1134	1.279e-42	164.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2U47T@28211|Alphaproteobacteria,2KHKD@204458|Caulobacterales	204458|Caulobacterales	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
SRR25158456_k127_2947557_19	1313294.BPA_0088800	3.685e-11	76.0	COG0455@1|root,COG0455@2|Bacteria,2J5K5@203691|Spirochaetes	203691|Spirochaetes	D	ATP-binding protein	ylxH-2	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
SRR25158456_k127_2947557_14	309799.DICTH_1701	9.697e-45	176.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158456_k127_2947557_17	1121920.AUAU01000014_gene2807	6.556e-21	106.0	COG0558@1|root,COG0558@2|Bacteria,3Y4S5@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158456_k127_2947557_11	234267.Acid_2025	1.991e-66	242.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria	57723|Acidobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158456_k127_2947557_7	234267.Acid_3900	3.692e-88	294.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria	57723|Acidobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158456_k127_2947557_3	671143.DAMO_2181	1.504e-179	571.0	COG1219@1|root,COG1219@2|Bacteria,2NNN2@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158456_k127_2947557_0	404589.Anae109_3418	1.221e-265	844.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158456_k127_2947557_20	234267.Acid_2620	0.0006336	52.0	COG2304@1|root,COG2304@2|Bacteria,3Y3ER@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2947557_13	1123009.AUID01000017_gene393	1.42e-47	178.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,2699G@186813|unclassified Clostridiales	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SRR25158456_k127_2947557_1	1184267.A11Q_77	1.432e-199	634.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2MSUT@213481|Bdellovibrionales,2WIQN@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158456_k127_2947557_12	42256.RradSPS_2132	2.919e-49	185.0	2BUN3@1|root,32PYT@2|Bacteria,2IJZP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
SRR25158456_k127_2947557_4	42256.RradSPS_2133	5.597e-176	563.0	COG4637@1|root,COG4637@2|Bacteria,2HRMF@201174|Actinobacteria,4CTPD@84995|Rubrobacteria	84995|Rubrobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
SRR25158456_k127_2947557_18	933262.AXAM01000018_gene1000	4.971e-18	87.0	2ED2F@1|root,336ZC@2|Bacteria,1N758@1224|Proteobacteria,42WNC@68525|delta/epsilon subdivisions,2WSHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SRR25158456_k127_2947557_6	1121920.AUAU01000005_gene1020	9.103e-122	416.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2947557_2	404589.Anae109_1344	1.205e-192	625.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,437F6@68525|delta/epsilon subdivisions,2X2MS@28221|Deltaproteobacteria,2YTV3@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SRR25158456_k127_2947557_5	330214.NIDE3591	2.651e-163	543.0	COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158456_k127_2947557_10	671143.DAMO_2629	9.181e-70	245.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158456_k127_2947557_9	518766.Rmar_2343	8.198e-75	273.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1FIW0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158456_k127_2947557_16	1382359.JIAL01000001_gene2662	5.254e-31	137.0	COG1463@1|root,COG1463@2|Bacteria,3Y3SX@57723|Acidobacteria,2JIP6@204432|Acidobacteriia	204432|Acidobacteriia	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158456_k127_2947557_8	192952.MM_1134	4.977e-81	291.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,2N966@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158456_k127_2947557_15	237368.SCABRO_02716	5.999e-32	134.0	COG1208@1|root,COG1208@2|Bacteria,2J0B4@203682|Planctomycetes	203682|Planctomycetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SRR25158456_k127_2966976_3	671143.DAMO_0676	3.369e-85	301.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158456_k127_2966976_4	1313301.AUGC01000007_gene554	1.651e-78	274.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158456_k127_2966976_7	1382356.JQMP01000003_gene1611	2.31e-14	80.0	COG0508@1|root,COG1073@1|root,COG0508@2|Bacteria,COG1073@2|Bacteria,2G619@200795|Chloroflexi,27YZE@189775|Thermomicrobia	189775|Thermomicrobia	C	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl,E3_binding,Hydrolase_4
SRR25158456_k127_2966976_0	266117.Rxyl_2324	7.989e-129	421.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CRUB@84995|Rubrobacteria	84995|Rubrobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158456_k127_2966976_1	266117.Rxyl_2325	4.1e-113	377.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4CS4C@84995|Rubrobacteria	84995|Rubrobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158456_k127_2966976_8	331678.Cphamn1_1154	2.213e-13	73.0	COG2002@1|root,COG2002@2|Bacteria,1FFJT@1090|Chlorobi	1090|Chlorobi	K	TIGRFAM transcriptional regulator, AbrB family	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158456_k127_2966976_2	234267.Acid_2167	2.674e-98	344.0	COG0477@1|root,COG2814@2|Bacteria,3Y47I@57723|Acidobacteria	57723|Acidobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158456_k127_2966976_5	414684.RC1_1807	3.76e-42	160.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,2JS5T@204441|Rhodospirillales	204441|Rhodospirillales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158456_k127_2966976_6	886293.Sinac_2273	1.052e-33	137.0	COG0220@1|root,COG0220@2|Bacteria,2IZJM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
SRR25158456_k127_2966976_11	1449346.JQMO01000002_gene261	7.189e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,2M2X6@2063|Kitasatospora	201174|Actinobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158456_k127_2966976_10	521098.Aaci_1747	4.106e-05	56.0	COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,1VQJP@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
SRR25158456_k127_2968610_9	65393.PCC7424_4288	3.092e-10	62.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1	ko:K11894,ko:K11913,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	3.A.23.1	-	-	FHA,Yop-YscD_cpl,zf-ribbon_3
SRR25158456_k127_2968610_6	65393.PCC7424_4289	3.65e-15	82.0	COG0457@1|root,COG0457@2|Bacteria,1GEMM@1117|Cyanobacteria	1117|Cyanobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_2968610_1	204669.Acid345_0279	1.929e-99	343.0	COG1570@1|root,COG1570@2|Bacteria,3Y3DP@57723|Acidobacteria,2JIQN@204432|Acidobacteriia	204432|Acidobacteriia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158456_k127_2968610_7	264462.Bd0198	2.116e-14	78.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MM@1224|Proteobacteria,42X37@68525|delta/epsilon subdivisions,2WSNI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158456_k127_2968610_2	443143.GM18_1115	3.731e-82	287.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158456_k127_2968610_0	498761.HM1_0295	7.515e-226	719.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158456_k127_2968610_5	449447.MAE_62210	1.104e-21	104.0	COG2402@1|root,COG2402@2|Bacteria,1G7JM@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_2968610_3	215803.DB30_0789	1.11e-75	265.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158456_k127_2968610_4	358823.DF19_19510	9.56e-70	245.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158456_k127_2968610_8	1123371.ATXH01000013_gene1507	3.329e-11	65.0	COG1826@1|root,COG1826@2|Bacteria,2GIP7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158456_k127_2971191_11	472759.Nhal_2504	1.105e-15	77.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158456_k127_2971191_9	472759.Nhal_2505	4.336e-22	100.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158456_k127_2971191_4	1122132.AQYH01000018_gene1147	6.991e-57	208.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,4B83S@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	3.2.2.21	ko:K01247,ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
SRR25158456_k127_2971191_0	867845.KI911784_gene3180	4.339e-95	331.0	COG0492@1|root,COG0492@2|Bacteria,2G87N@200795|Chloroflexi,377CC@32061|Chloroflexia	32061|Chloroflexia	O	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
SRR25158456_k127_2971191_8	1232410.KI421421_gene3541	6.108e-24	106.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,42WGY@68525|delta/epsilon subdivisions,2WS4W@28221|Deltaproteobacteria,43VDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
SRR25158456_k127_2971191_10	1279009.ADICEAN_01769	1.809e-16	87.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,47RCF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2971191_7	1240350.AMZE01000104_gene1744	1.085e-26	114.0	COG0454@1|root,COG1670@1|root,COG0456@2|Bacteria,COG1670@2|Bacteria,1PGT5@1224|Proteobacteria,1RWFQ@1236|Gammaproteobacteria,1YZ40@136845|Pseudomonas putida group	1236|Gammaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158456_k127_2971191_5	43759.JNWK01000035_gene3251	1.546e-43	175.0	COG4447@1|root,COG4447@2|Bacteria,2IGT5@201174|Actinobacteria	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2971191_6	1380355.JNIJ01000021_gene3699	8.997e-34	134.0	COG5485@1|root,COG5485@2|Bacteria,1RE0T@1224|Proteobacteria,2U870@28211|Alphaproteobacteria,3K0B7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158456_k127_2971191_2	221288.JH992901_gene3698	2.316e-75	284.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1G39C@1117|Cyanobacteria,1JKE1@1189|Stigonemataceae	1117|Cyanobacteria	S	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12
SRR25158456_k127_2971191_3	118173.KB235910_gene4780	2.804e-71	271.0	COG0775@1|root,COG4249@1|root,COG0775@2|Bacteria,COG4249@2|Bacteria,1GQV4@1117|Cyanobacteria,1HI1U@1150|Oscillatoriales	1117|Cyanobacteria	F	GUN4-like	-	-	-	-	-	-	-	-	-	-	-	-	GUN4
SRR25158456_k127_2976553_1	484770.UFO1_0506	5.217e-69	267.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4H37S@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158456_k127_2976553_0	234267.Acid_4393	1.815e-144	490.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2980417_2	1047013.AQSP01000135_gene1613	5.15e-70	248.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158456_k127_2980417_3	290512.Paes_0751	1.634e-33	138.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158456_k127_2980417_4	1125863.JAFN01000001_gene3051	1.341e-29	129.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SRR25158456_k127_2980417_6	1437425.CSEC_1446	3.237e-08	58.0	COG0268@1|root,COG0268@2|Bacteria,2JGDY@204428|Chlamydiae	204428|Chlamydiae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158456_k127_2980417_1	378806.STAUR_6898	2.844e-104	344.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158456_k127_2980417_5	1499967.BAYZ01000182_gene4418	6.714e-18	95.0	COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
SRR25158456_k127_2980417_0	1121468.AUBR01000001_gene529	4.639e-221	704.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158456_k127_2992071_1	584708.Apau_0039	2.967e-167	535.0	COG0538@1|root,COG0538@2|Bacteria,3TACN@508458|Synergistetes	508458|Synergistetes	C	isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158456_k127_2992071_23	457570.Nther_2043	3.619e-08	64.0	COG1664@1|root,COG1664@2|Bacteria,1VBC3@1239|Firmicutes,24NSR@186801|Clostridia	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2992071_15	1379698.RBG1_1C00001G1704	1.829e-39	153.0	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_2992071_6	96561.Dole_2132	8.698e-78	269.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria,2MJC9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_2992071_12	469383.Cwoe_4634	2.349e-50	189.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158456_k127_2992071_13	1123401.JHYQ01000045_gene3372	1.031e-40	155.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,4610M@72273|Thiotrichales	72273|Thiotrichales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158456_k127_2992071_5	886293.Sinac_0418	1.077e-78	286.0	COG0628@1|root,COG0628@2|Bacteria,2IXF5@203682|Planctomycetes	203682|Planctomycetes	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158456_k127_2992071_22	386456.JQKN01000001_gene2172	1.992e-08	67.0	COG1807@1|root,arCOG00566@2157|Archaea	2157|Archaea	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158456_k127_2992071_24	682795.AciX8_4327	1.662e-07	66.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2992071_11	84531.JMTZ01000032_gene300	8.431e-64	228.0	COG3170@1|root,COG3170@2|Bacteria,1R3TU@1224|Proteobacteria,1S63C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the peptidase M12A family	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
SRR25158456_k127_2992071_19	342610.Patl_0327	2.576e-21	110.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,1RMCD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO1525	DCD,dUTPase
SRR25158456_k127_2992071_0	1499967.BAYZ01000136_gene58	2.189e-184	589.0	COG1003@1|root,COG1003@2|Bacteria,2NNSG@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
SRR25158456_k127_2992071_3	696369.KI912183_gene1657	9.372e-123	409.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158456_k127_2992071_14	525904.Tter_1497	4.406e-40	166.0	COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158456_k127_2992071_2	646529.Desaci_3735	1.892e-124	409.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,261AX@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158456_k127_2992071_20	215803.DB30_7610	1.894e-17	97.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158456_k127_2992071_16	379066.GAU_0485	3.05e-37	155.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1ZT7F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
SRR25158456_k127_2992071_17	999630.TUZN_0409	3.159e-36	152.0	COG2379@1|root,arCOG04170@2157|Archaea,2XPZD@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM MOFRL domain protein	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158456_k127_2992071_9	1267534.KB906754_gene3068	7.972e-69	270.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria,2JHS8@204432|Acidobacteriia	204432|Acidobacteriia	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRR25158456_k127_2992071_7	1267535.KB906767_gene3597	6.299e-72	280.0	COG4775@1|root,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria,2JHK5@204432|Acidobacteriia	204432|Acidobacteriia	M	surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
SRR25158456_k127_2992071_10	471854.Dfer_5630	1.053e-68	255.0	COG0500@1|root,COG2226@2|Bacteria,4P07B@976|Bacteroidetes,47U6E@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_2992071_4	1128421.JAGA01000002_gene1776	6.353e-87	308.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
SRR25158456_k127_2992071_18	1211815.CBYP010000073_gene3631	7.017e-35	152.0	COG1215@1|root,COG1215@2|Bacteria,2H4BF@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SRR25158456_k127_2992071_8	1128421.JAGA01000002_gene1777	4.397e-70	245.0	COG2301@1|root,COG2301@2|Bacteria	2|Bacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	3.1.2.30,4.1.3.25,4.1.3.34	ko:K01644,ko:K14451,ko:K18292	ko00630,ko00660,ko01100,ko01120,ko01200,ko02020,map00630,map00660,map01100,map01120,map01200,map02020	M00373	R00237,R00362,R10612	RC00004,RC00014,RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI,PEP-utilizers_C
SRR25158456_k127_2992071_21	1415778.JQMM01000001_gene1202	4.32e-12	70.0	COG0500@1|root,COG2226@2|Bacteria,1R3QX@1224|Proteobacteria,1RYQ8@1236|Gammaproteobacteria,1J5CI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158456_k127_3008636_4	1173024.KI912148_gene2595	1.636e-25	111.0	COG2329@1|root,COG2329@2|Bacteria,1GKCK@1117|Cyanobacteria,1JKW7@1189|Stigonemataceae	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158456_k127_3008636_5	643867.Ftrac_1661	4.359e-10	68.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRR25158456_k127_3008636_1	376686.Fjoh_2012	1.336e-144	504.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2NSP5@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_3008636_0	1267535.KB906767_gene1072	3.672e-147	471.0	COG0175@1|root,COG0175@2|Bacteria,3Y36I@57723|Acidobacteria,2JIQ5@204432|Acidobacteriia	204432|Acidobacteriia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158456_k127_3008636_2	1267535.KB906767_gene1073	2.4e-131	449.0	COG2895@1|root,COG2895@2|Bacteria,3Y3AW@57723|Acidobacteria,2JI68@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
SRR25158456_k127_3008636_3	204669.Acid345_2373	2.181e-57	221.0	COG0155@1|root,COG0155@2|Bacteria,3Y2R8@57723|Acidobacteria,2JHXQ@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM nitrite and sulphite reductase 4Fe-4S	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158456_k127_3010750_1	1128427.KB904821_gene3311	7.091e-54	201.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1GDIS@1117|Cyanobacteria,1HHSX@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase (GGDEF domain)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_4,PAS_9,Response_reg
SRR25158456_k127_3010750_2	1254432.SCE1572_04190	1.588e-39	153.0	COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria	1224|Proteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SRR25158456_k127_3010750_5	1521187.JPIM01000023_gene785	1.874e-08	66.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G8ES@200795|Chloroflexi,3759V@32061|Chloroflexia	32061|Chloroflexia	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
SRR25158456_k127_3010750_4	69395.JQLZ01000001_gene3230	7.927e-33	141.0	COG2885@1|root,COG2885@2|Bacteria,1RDG7@1224|Proteobacteria,2U8K5@28211|Alphaproteobacteria,2KGIE@204458|Caulobacterales	204458|Caulobacterales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158456_k127_3010750_0	290397.Adeh_0431	3.787e-85	301.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria,2Z364@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158456_k127_3010750_6	1265503.KB905163_gene2061	5.99e-08	65.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1THKF@1236|Gammaproteobacteria,2Q74Z@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SRR25158456_k127_3013574_5	1304888.ATWF01000001_gene1130	1.789e-09	66.0	COG1792@1|root,COG1792@2|Bacteria,2GFFR@200930|Deferribacteres	200930|Deferribacteres	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158456_k127_3013574_0	234267.Acid_3811	1.788e-162	539.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria	57723|Acidobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158456_k127_3013574_4	443144.GM21_1523	1.846e-13	83.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,LysM,fn3
SRR25158456_k127_3013574_2	1121918.ARWE01000001_gene1046	2.424e-55	217.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,43RYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SurA N-terminal domain	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158456_k127_3013574_3	391625.PPSIR1_04398	3.336e-30	123.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158456_k127_3013574_1	316067.Geob_1034	2.138e-84	319.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,43SWS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat
SRR25158456_k127_3013918_0	945713.IALB_1500	2.55e-115	392.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	dsbD	-	1.8.1.8	ko:K04084,ko:K06196	-	-	-	-	ko00000,ko01000,ko02000,ko03110	5.A.1.1,5.A.1.2	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
SRR25158456_k127_3013918_2	1123253.AUBD01000008_gene333	6.274e-15	89.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1SDIM@1236|Gammaproteobacteria,1X7GX@135614|Xanthomonadales	135614|Xanthomonadales	J	RNA-binding protein	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
SRR25158456_k127_3013918_1	748247.AZKH_1488	5.349e-39	160.0	COG0726@1|root,COG0726@2|Bacteria,1MWUE@1224|Proteobacteria,2VQN4@28216|Betaproteobacteria,2KZZA@206389|Rhodocyclales	206389|Rhodocyclales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158456_k127_3013918_3	1267534.KB906759_gene1849	3.996e-12	75.0	COG1729@1|root,COG1729@2|Bacteria,3Y4ME@57723|Acidobacteria,2JJA9@204432|Acidobacteriia	204432|Acidobacteriia	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
SRR25158456_k127_3013918_4	1242864.D187_006743	1.028e-10	73.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,42ZKN@68525|delta/epsilon subdivisions,2WUTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158456_k127_3015623_0	398767.Glov_2372	5.236e-189	608.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158456_k127_3015623_3	234267.Acid_3348	1.036e-57	217.0	COG0624@1|root,COG0624@2|Bacteria,3Y2XS@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158456_k127_3015623_1	1047013.AQSP01000123_gene1523	2.118e-116	410.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_3015623_2	1047013.AQSP01000131_gene1840	5.897e-79	296.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158456_k127_3018870_8	1298880.AUEV01000008_gene2550	0.0002277	51.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria	201174|Actinobacteria	O	AAA ATPase central domain protein	spoVK	-	-	-	-	-	-	-	-	-	-	-	AAA,Beta_helix
SRR25158456_k127_3018870_10	331678.Cphamn1_1380	0.000946	51.0	COG0457@1|root,COG0457@2|Bacteria	331678.Cphamn1_1380|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3018870_6	483219.LILAB_21380	2.516e-25	106.0	2EAYI@1|root,334ZG@2|Bacteria,1N8W1@1224|Proteobacteria,432ZT@68525|delta/epsilon subdivisions,2WXAQ@28221|Deltaproteobacteria,2Z2VM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3018870_4	880073.Calab_3797	3.654e-49	198.0	COG2208@1|root,COG3292@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,HisKA_3,PAS_9,Reg_prop,Response_reg,SpoIIE,Y_Y_Y
SRR25158456_k127_3018870_7	1313421.JHBV01000038_gene2852	1.473e-21	111.0	COG1404@1|root,COG1520@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4PMDA@976|Bacteroidetes	976|Bacteroidetes	O	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PKD,Sortilin-Vps10
SRR25158456_k127_3018870_3	1340493.JNIF01000003_gene2146	6.264e-51	189.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
SRR25158456_k127_3018870_9	161156.JQKW01000012_gene73	0.0009065	44.0	COG4980@1|root,COG4980@2|Bacteria,2GI2V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
SRR25158456_k127_3018870_2	497964.CfE428DRAFT_2412	3.698e-77	267.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Phosphoglycerate mutase family	phoE	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158456_k127_3018870_1	298655.KI912266_gene1647	1.06e-89	336.0	COG0457@1|root,COG3118@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3629@2|Bacteria,2IGHC@201174|Actinobacteria	201174|Actinobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158456_k127_3018870_0	32057.KB217483_gene8946	6.538e-193	680.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,1GPZZ@1117|Cyanobacteria,1HJUW@1161|Nostocales	1117|Cyanobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VWA
SRR25158456_k127_3018995_2	643867.Ftrac_1510	7.853e-72	254.0	COG1960@1|root,COG1960@2|Bacteria,4NEM4@976|Bacteroidetes,47U95@768503|Cytophagia	976|Bacteroidetes	C	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158456_k127_3018995_5	1192034.CAP_8182	1.421e-28	121.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158456_k127_3018995_0	861299.J421_1936	7.08e-235	741.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	2|Bacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158456_k127_3018995_4	42256.RradSPS_2282	1.182e-40	173.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_3018995_3	157783.LK03_10480	2.788e-62	228.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RZAD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	aminotransferase	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_3018995_1	365046.Rta_16960	8.083e-118	402.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria,4AAM4@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158456_k127_3018995_6	1121428.DESHY_160137___1	1.884e-20	98.0	COG3568@1|root,COG3568@2|Bacteria,1V9H0@1239|Firmicutes,24KPC@186801|Clostridia,263C6@186807|Peptococcaceae	186801|Clostridia	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158456_k127_3019746_7	1382356.JQMP01000003_gene2027	6.015e-61	218.0	COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia	189775|Thermomicrobia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158456_k127_3019746_8	382464.ABSI01000013_gene1783	6.393e-18	96.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_3019746_6	1123073.KB899241_gene1850	7.818e-77	271.0	COG3358@1|root,COG3358@2|Bacteria,1R9CT@1224|Proteobacteria,1SP2S@1236|Gammaproteobacteria,1X42J@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158456_k127_3019746_0	1163407.UU7_01237	1.668e-194	619.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1X4BQ@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158456_k127_3019746_10	1294143.H681_08255	8.084e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,1N6SV@1224|Proteobacteria,1S570@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	fecI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_3019746_11	797302.Halru_2425	3.097e-06	59.0	COG0457@1|root,COG1321@1|root,arCOG03408@1|root,arCOG02100@2157|Archaea,arCOG03045@2157|Archaea,arCOG03409@2157|Archaea	2157|Archaea	K	PFAM Archaeal ATPase	-	-	-	ko:K03709,ko:K06921	-	-	-	-	ko00000,ko03000	-	-	-	ATPase_2,Fe_dep_repr_C,Fe_dep_repress
SRR25158456_k127_3019746_4	448385.sce9074	9.161e-90	305.0	COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria	1224|Proteobacteria	S	ABC transporter, (ATP-binding protein)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158456_k127_3019746_5	448385.sce9075	3.199e-79	281.0	COG1668@1|root,COG1668@2|Bacteria,1R62N@1224|Proteobacteria	1224|Proteobacteria	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158456_k127_3019746_3	1047013.AQSP01000133_gene2112	9.073e-156	514.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158456_k127_3019746_2	290397.Adeh_0408	2.584e-161	547.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158456_k127_3019746_12	1267533.KB906738_gene2061	2.497e-05	57.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_3019746_9	251229.Chro_5493	3.681e-15	85.0	COG2227@1|root,COG2227@2|Bacteria,1G96N@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158456_k127_3019746_1	414684.RC1_2702	4.784e-188	610.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2JPCA@204441|Rhodospirillales	204441|Rhodospirillales	E	NAD-specific glutamate dehydrogenase	gdhA	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158456_k127_3025261_2	340.xcc-b100_4275	3.389e-92	319.0	COG0793@1|root,COG2207@1|root,COG0793@2|Bacteria,COG2207@2|Bacteria,1MW4H@1224|Proteobacteria,1TBRP@1236|Gammaproteobacteria,1X9A1@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158456_k127_3025261_4	1121439.dsat_0540	5.935e-69	241.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,2M80V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
SRR25158456_k127_3025261_0	1267535.KB906767_gene2802	1.913e-302	940.0	COG0443@1|root,COG0443@2|Bacteria,3Y2XU@57723|Acidobacteria,2JHT1@204432|Acidobacteriia	204432|Acidobacteriia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158456_k127_3025261_7	1267533.KB906736_gene1388	6.572e-27	117.0	COG0789@1|root,COG0789@2|Bacteria,3Y4KX@57723|Acidobacteria,2JJA1@204432|Acidobacteriia	204432|Acidobacteriia	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158456_k127_3025261_5	211165.AJLN01000141_gene2499	4.497e-60	218.0	2DMH4@1|root,32RH1@2|Bacteria,1GF26@1117|Cyanobacteria	1117|Cyanobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158456_k127_3025261_3	335543.Sfum_3053	1.062e-75	267.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,2MR3S@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158456_k127_3025261_9	1173263.Syn7502_03353	4.988e-19	96.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158456_k127_3025261_6	714943.Mucpa_4075	3.814e-43	165.0	COG0431@1|root,COG0431@2|Bacteria,4NQ3Y@976|Bacteroidetes,1ISVG@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158456_k127_3025261_11	388467.A19Y_2928	0.0001157	50.0	COG2929@1|root,COG2929@2|Bacteria,1G7VS@1117|Cyanobacteria,1HHKU@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR25158456_k127_3025261_10	1173028.ANKO01000041_gene3194	1.644e-12	73.0	2C6B2@1|root,335GA@2|Bacteria,1G9BT@1117|Cyanobacteria,1HDYH@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3025261_1	861299.J421_2998	3.305e-195	643.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_3025261_8	935863.AWZR01000004_gene384	1.272e-23	108.0	COG0346@1|root,COG0346@2|Bacteria,1QAU1@1224|Proteobacteria,1TECX@1236|Gammaproteobacteria,1XBJ0@135614|Xanthomonadales	135614|Xanthomonadales	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_302666_4	404589.Anae109_0988	3.446e-127	421.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42P67@68525|delta/epsilon subdivisions,2WJP7@28221|Deltaproteobacteria,2Z34G@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
SRR25158456_k127_302666_3	880073.Calab_3419	4.803e-131	426.0	COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46,4.2.1.76	ko:K01710,ko:K12450	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R00293,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
SRR25158456_k127_302666_13	1121403.AUCV01000015_gene4714	7.811e-15	79.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,43ADP@68525|delta/epsilon subdivisions,2WKI7@28221|Deltaproteobacteria,2MJ7M@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_302666_5	316274.Haur_4146	1.396e-126	413.0	COG0372@1|root,COG0372@2|Bacteria,2G7NR@200795|Chloroflexi,3776D@32061|Chloroflexia	32061|Chloroflexia	H	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158456_k127_302666_6	266117.Rxyl_2556	1.593e-119	395.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria,4CT9Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Helix-turn-helix domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
SRR25158456_k127_302666_0	1121920.AUAU01000010_gene50	6.613e-168	539.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158456_k127_302666_14	35754.JNYJ01000032_gene1773	9.034e-15	87.0	2A08G@1|root,30NBR@2|Bacteria,2H1QF@201174|Actinobacteria,4DICX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_302666_2	679897.HMU08020	6.447e-161	529.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2YMDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158456_k127_302666_8	1128421.JAGA01000003_gene3443	4.706e-101	344.0	COG1364@1|root,COG1364@2|Bacteria,2NQKS@2323|unclassified Bacteria	2|Bacteria	E	ArgJ family	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35,2.7.2.8	ko:K00620,ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158456_k127_302666_7	1216007.AOPM01000002_gene2564	8.203e-109	386.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,2Q0IQ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	belongs to the lyase 1 family. Argininosuccinate lyase subfamily	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844,M00845	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
SRR25158456_k127_302666_1	926569.ANT_12440	1.259e-161	518.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the argininosuccinate synthase family. Type	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158456_k127_302666_9	330084.JNYZ01000062_gene5490	3.751e-98	334.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4DX7N@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158456_k127_302666_11	1122611.KB904007_gene7739	6.847e-42	175.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4EHH3@85012|Streptosporangiales	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158456_k127_302666_10	398767.Glov_3188	1.437e-84	293.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158456_k127_302666_12	696369.KI912183_gene1390	4.386e-21	99.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,2625T@186807|Peptococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158456_k127_304210_11	671143.DAMO_2422	2.976e-20	99.0	28VTP@1|root,2ZHVD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_304210_9	384676.PSEEN2491	1.935e-24	119.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158456_k127_304210_1	378806.STAUR_6142	5.791e-104	353.0	COG0535@1|root,COG0535@2|Bacteria,1ND1B@1224|Proteobacteria,42RQW@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158456_k127_304210_0	378806.STAUR_6143	2.947e-148	488.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
SRR25158456_k127_304210_16	378806.STAUR_6144	0.0001963	53.0	2EH27@1|root,33AU6@2|Bacteria,1NN3U@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_304210_15	931627.MycrhDRAFT_6890	8.264e-09	67.0	2DC1N@1|root,2ZCGR@2|Bacteria,2I9JK@201174|Actinobacteria,2378H@1762|Mycobacteriaceae	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM60
SRR25158456_k127_304210_10	1144275.COCOR_03481	6.763e-21	108.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25,ParA
SRR25158456_k127_304210_7	338966.Ppro_0181	4.452e-27	113.0	2E37J@1|root,32Y79@2|Bacteria,1NGYR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_304210_4	1121904.ARBP01000001_gene5914	8.14e-57	218.0	COG4249@1|root,COG4249@2|Bacteria,4NH9I@976|Bacteroidetes,47XC3@768503|Cytophagia	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158456_k127_304210_6	102129.Lepto7375DRAFT_0022	3.877e-27	130.0	COG0457@1|root,COG3210@1|root,COG4995@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,CHAT,Haemagg_act,TPR_12,TPR_7
SRR25158456_k127_304210_17	471856.Jden_0811	0.0002086	51.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_304210_13	1378168.N510_03002	1.074e-09	71.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes	1239|Firmicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cna_B,FctA
SRR25158456_k127_304210_2	1144275.COCOR_05170	2.993e-93	321.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_304210_3	768671.ThimaDRAFT_2804	6.034e-72	246.0	COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,1SG1X@1236|Gammaproteobacteria,1WZ0T@135613|Chromatiales	135613|Chromatiales	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
SRR25158456_k127_304210_8	760568.Desku_2090	4.34e-26	109.0	COG1724@1|root,COG1724@2|Bacteria,1VZ5D@1239|Firmicutes,252ZW@186801|Clostridia	186801|Clostridia	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158456_k127_304210_12	472759.Nhal_3915	3.993e-20	105.0	COG1598@1|root,COG1598@2|Bacteria,1P4UT@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_304210_5	1340493.JNIF01000003_gene4542	2.271e-50	198.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria	57723|Acidobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158456_k127_304576_2	405948.SACE_3780	1.704e-50	191.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_304576_5	1121272.KB903259_gene6508	2.655e-29	122.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4DDVR@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158456_k127_304576_1	1163407.UU7_05623	5.193e-74	259.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	yrgI	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158456_k127_304576_0	395495.Lcho_1966	1.043e-113	371.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,2VN38@28216|Betaproteobacteria,1KMHM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
SRR25158456_k127_304576_4	234267.Acid_3176	2.757e-49	178.0	COG0346@1|root,COG0346@2|Bacteria,3Y8C4@57723|Acidobacteria	57723|Acidobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158456_k127_304576_7	290317.Cpha266_1704	1.347e-23	113.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
SRR25158456_k127_304576_6	945550.VISI1226_03910	5.495e-24	108.0	2BXBF@1|root,32T94@2|Bacteria,1QJPA@1224|Proteobacteria,1THQ7@1236|Gammaproteobacteria,1XX4Z@135623|Vibrionales	135623|Vibrionales	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695
SRR25158456_k127_304576_3	903818.KI912269_gene149	1.457e-49	207.0	COG4932@1|root,COG4932@2|Bacteria,3Y8E2@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158456_k127_304576_8	1297742.A176_00743	4.954e-15	92.0	COG3210@1|root,COG4257@1|root,COG5276@1|root,COG3210@2|Bacteria,COG4257@2|Bacteria,COG5276@2|Bacteria,1R2UD@1224|Proteobacteria,43DGX@68525|delta/epsilon subdivisions,2X8NS@28221|Deltaproteobacteria,2Z130@29|Myxococcales	28221|Deltaproteobacteria	U	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158456_k127_3055998_0	1303518.CCALI_02898	0.0	1139.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158456_k127_3055998_5	994573.T472_0203045	1.909e-13	80.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia,36KFN@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158456_k127_3055998_4	1122211.JMLW01000050_gene1357	3.245e-24	115.0	COG1708@1|root,COG1708@2|Bacteria,1MYTD@1224|Proteobacteria	1224|Proteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF294,NTP_transf_2
SRR25158456_k127_3055998_1	526225.Gobs_3738	4.894e-311	984.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4ERX5@85013|Frankiales	201174|Actinobacteria	L	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
SRR25158456_k127_3055998_6	1121098.HMPREF1534_01115	3.749e-05	53.0	COG1396@1|root,COG1396@2|Bacteria,4NR5F@976|Bacteroidetes,2FTP9@200643|Bacteroidia,4ARFQ@815|Bacteroidaceae	976|Bacteroidetes	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158456_k127_3055998_2	1340493.JNIF01000003_gene4071	1e-132	436.0	COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158456_k127_3055998_3	448385.sce1953	1.594e-71	276.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_3057229_3	1223410.KN050846_gene2796	1.049e-129	434.0	COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,1HWU3@117743|Flavobacteriia	976|Bacteroidetes	V	ABC transporter	mdlA	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_3057229_0	240015.ACP_3490	1.269e-179	606.0	COG1132@1|root,COG1132@2|Bacteria,3Y2ZR@57723|Acidobacteria,2JHJA@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_3057229_5	1247963.JPHU01000010_gene2270	3.026e-09	61.0	2E9WT@1|root,3342I@2|Bacteria,1NBEH@1224|Proteobacteria,2UFGC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	MA20_00895	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
SRR25158456_k127_3057229_1	671143.DAMO_3080	1.135e-163	536.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158456_k127_3057229_2	240016.ABIZ01000001_gene231	8.541e-134	444.0	2DBCY@1|root,2Z8GH@2|Bacteria	2|Bacteria	S	PFAM Tyrosinase	-	-	1.10.3.1,1.14.18.1	ko:K00422,ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00031,R00045,R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	PPO1_DWL,PPO1_KFDV,Tyrosinase
SRR25158456_k127_3057229_4	1266925.JHVX01000002_gene863	4.93e-10	66.0	2CCQK@1|root,336HE@2|Bacteria,1PWK3@1224|Proteobacteria,2WC4K@28216|Betaproteobacteria,374AD@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_306299_1	264732.Moth_1809	6.515e-187	597.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
SRR25158456_k127_306299_0	264732.Moth_1811	2.817e-245	784.0	COG3280@1|root,COG3280@2|Bacteria,1UERK@1239|Firmicutes,25JR7@186801|Clostridia,42HXY@68295|Thermoanaerobacterales	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158456_k127_306299_2	671143.DAMO_1432	9.348e-37	147.0	COG4636@1|root,COG4636@2|Bacteria,2NRM2@2323|unclassified Bacteria	2|Bacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_3063546_23	243275.TDE_0760	3.177e-06	58.0	2DR9X@1|root,33AUW@2|Bacteria,2J7VH@203691|Spirochaetes	203691|Spirochaetes	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
SRR25158456_k127_3063546_11	316067.Geob_1393	2.554e-57	213.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,43T7W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
SRR25158456_k127_3063546_5	234267.Acid_1646	7.677e-109	385.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
SRR25158456_k127_3063546_1	1047013.AQSP01000083_gene1192	1.316e-153	500.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	nla19	-	-	ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_3063546_22	525904.Tter_2790	3.561e-08	67.0	2CA4F@1|root,33DCB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3063546_2	518766.Rmar_0074	7.386e-149	501.0	COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,1FIRV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Peptidase_M14
SRR25158456_k127_3063546_21	1244869.H261_09242	8.118e-22	97.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,2UFRK@28211|Alphaproteobacteria,2JUQG@204441|Rhodospirillales	204441|Rhodospirillales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_3063546_18	264198.Reut_C6344	6.535e-31	129.0	COG3744@1|root,COG3744@2|Bacteria,1NA89@1224|Proteobacteria,2VUYN@28216|Betaproteobacteria,1KFTZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_3063546_10	639030.JHVA01000001_gene1792	4.228e-64	223.0	COG2128@1|root,COG2128@2|Bacteria,3Y4TK@57723|Acidobacteria,2JJJ6@204432|Acidobacteriia	204432|Acidobacteriia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158456_k127_3063546_0	215803.DB30_6272	6.922e-182	581.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,42RMX@68525|delta/epsilon subdivisions,2X5I2@28221|Deltaproteobacteria,2Z35V@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158456_k127_3063546_8	204669.Acid345_3359	3.396e-80	276.0	COG1355@1|root,COG1355@2|Bacteria,3Y5Z0@57723|Acidobacteria,2JNSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SRR25158456_k127_3063546_4	671143.DAMO_2558	2.816e-124	416.0	COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158456_k127_3063546_20	1267533.KB906740_gene246	1.319e-25	109.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria,2JJNQ@204432|Acidobacteriia	204432|Acidobacteriia	K	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158456_k127_3063546_14	671143.DAMO_1641	2.548e-48	186.0	COG0241@1|root,COG0859@1|root,COG0241@2|Bacteria,COG0859@2|Bacteria,2NPK4@2323|unclassified Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	rfaF	-	2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28	ko:K02841,ko:K02843,ko:K02849,ko:K03271,ko:K03272,ko:K03273	ko00540,ko01100,map00540,map01100	M00064,M00080	R05644,R05645,R05646,R05647,R09768,R09769,R09771	RC00002,RC00017,RC00078,RC00434	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Hydrolase_like
SRR25158456_k127_3063546_15	1047013.AQSP01000135_gene1573	5.133e-34	151.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158456_k127_3063546_16	1198114.AciX9_0840	1.199e-33	150.0	COG1663@1|root,COG1663@2|Bacteria,3Y5FQ@57723|Acidobacteria,2JJ24@204432|Acidobacteriia	204432|Acidobacteriia	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR25158456_k127_3063546_9	1267534.KB906757_gene860	1.245e-71	258.0	COG1519@1|root,COG1519@2|Bacteria,3Y3X5@57723|Acidobacteria,2JI61@204432|Acidobacteriia	204432|Acidobacteriia	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR25158456_k127_3063546_7	309801.trd_0861	3.116e-83	308.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,27XK0@189775|Thermomicrobia	189775|Thermomicrobia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158456_k127_3063546_12	1405.DJ92_414	4.193e-57	213.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07471,ko:K13652,ko:K19056	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,DinB_2,GyrI-like,HTH_18
SRR25158456_k127_3063546_17	1232410.KI421421_gene3682	2.301e-31	129.0	COG0454@1|root,COG0456@2|Bacteria,1NEWG@1224|Proteobacteria,42VG1@68525|delta/epsilon subdivisions,2WRCC@28221|Deltaproteobacteria,43UQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158456_k127_3063546_19	1121918.ARWE01000001_gene2592	6.155e-26	119.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158456_k127_3063546_6	234267.Acid_3178	5.035e-100	340.0	COG0373@1|root,COG0373@2|Bacteria,3Y3DQ@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158456_k127_3063546_13	1158345.JNLL01000001_gene1171	4.213e-53	214.0	COG0181@1|root,COG0181@2|Bacteria,2G3T1@200783|Aquificae	200783|Aquificae	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158456_k127_3063546_3	667014.Thein_0873	7.203e-135	448.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GH4Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158456_k127_3070156_12	243233.MCA0471	6.296e-59	224.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1RMA2@1236|Gammaproteobacteria,1XGYK@135618|Methylococcales	135618|Methylococcales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_3070156_1	234267.Acid_7636	3.074e-159	555.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158456_k127_3070156_9	234267.Acid_5931	1.746e-71	249.0	COG0730@1|root,COG0730@2|Bacteria,3Y4IM@57723|Acidobacteria	57723|Acidobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158456_k127_3070156_0	509635.N824_10045	1.017e-193	627.0	COG1132@1|root,COG1132@2|Bacteria,4NEBS@976|Bacteroidetes,1IPPE@117747|Sphingobacteriia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_3070156_5	279238.Saro_2825	2.4e-113	383.0	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,2TRSJ@28211|Alphaproteobacteria,2K00G@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158456_k127_3070156_2	1089550.ATTH01000001_gene669	6.564e-127	430.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
SRR25158456_k127_3070156_6	1089544.KB912942_gene5265	4.41e-82	282.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4DY3G@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158456_k127_3070156_16	1121344.JHZO01000004_gene1467	1.5e-37	158.0	COG4112@1|root,COG4112@2|Bacteria,1V277@1239|Firmicutes,252TJ@186801|Clostridia	186801|Clostridia	S	phosphoesterase (MutT family)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3070156_13	234267.Acid_5693	6.098e-55	202.0	COG1234@1|root,COG1234@2|Bacteria,3Y7KR@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158456_k127_3070156_15	880073.Calab_1754	3.164e-47	196.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
SRR25158456_k127_3070156_7	1267535.KB906767_gene1409	4.03e-77	274.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria,2JHNA@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158456_k127_3070156_17	511.JT27_14580	1.067e-10	67.0	28P93@1|root,2ZC2V@2|Bacteria,1RAKY@1224|Proteobacteria,2VQ51@28216|Betaproteobacteria,3T7J8@506|Alcaligenaceae	28216|Betaproteobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158456_k127_3070156_8	1254432.SCE1572_27920	7.332e-75	256.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,42T6B@68525|delta/epsilon subdivisions,2WPVS@28221|Deltaproteobacteria,2YWZ0@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158456_k127_3070156_11	342113.DM82_2824	7.354e-67	239.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,1K0VU@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158456_k127_3070156_18	8932.XP_005508415.1	3.001e-06	59.0	2CW9H@1|root,2RTXW@2759|Eukaryota,38VYN@33154|Opisthokonta,3CCXZ@33208|Metazoa,3DM6X@33213|Bilateria,48K21@7711|Chordata,49IU4@7742|Vertebrata,4GWIB@8782|Aves	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3070156_20	1117647.M5M_05880	8.936e-05	55.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1R2E9@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_12
SRR25158456_k127_3070156_10	1085623.GNIT_3572	7.495e-70	269.0	COG1404@1|root,COG5183@1|root,COG1404@2|Bacteria,COG5183@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,46BFY@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8,SLH
SRR25158456_k127_3070156_3	1173027.Mic7113_0442	1.41e-125	429.0	COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1G2MH@1117|Cyanobacteria,1H902@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
SRR25158456_k127_3070156_14	221288.JH992901_gene1990	3.066e-50	197.0	COG2201@1|root,COG2201@2|Bacteria,1G6AM@1117|Cyanobacteria,1JI7R@1189|Stigonemataceae	1117|Cyanobacteria	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
SRR25158456_k127_3070156_4	1487953.JMKF01000005_gene617	3.875e-114	372.0	COG1352@1|root,COG1352@2|Bacteria,1G1E5@1117|Cyanobacteria,1H94K@1150|Oscillatoriales	1117|Cyanobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRR25158456_k127_3072675_4	1132509.C447_05523	0.0003431	55.0	arCOG02282@1|root,arCOG02282@2157|Archaea	2157|Archaea	S	Phage integrase family	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,GAF_2,GAF_3,HTH_10,PAS_4,PAS_9,Phage_integrase
SRR25158456_k127_3072675_0	1379698.RBG1_1C00001G1351	1.255e-112	375.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158456_k127_3072675_1	379066.GAU_2111	6.646e-56	220.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158456_k127_3072675_3	862908.BMS_3186	1.247e-13	76.0	2EC0X@1|root,33605@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3072675_2	1382358.JHVN01000015_gene597	2.482e-50	188.0	COG4221@1|root,COG4221@2|Bacteria,1V9C1@1239|Firmicutes,4ISDS@91061|Bacilli,21WIK@150247|Anoxybacillus	91061|Bacilli	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_3073527_5	56110.Oscil6304_1395	9.711e-22	100.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_3073527_3	869210.Marky_1032	5.413e-46	179.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_3073527_1	497964.CfE428DRAFT_1237	6.772e-173	554.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158456_k127_3073527_0	497964.CfE428DRAFT_1238	9.618e-187	610.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158456_k127_3073527_4	497964.CfE428DRAFT_1239	2.388e-23	116.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3073527_2	1385935.N836_12895	3.532e-46	177.0	2DBEV@1|root,2Z8UT@2|Bacteria,1G3XJ@1117|Cyanobacteria,1HA4M@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3075709_11	1131451.O1K_19346	1.84e-08	60.0	2ANXP@1|root,31DYI@2|Bacteria,1QB8Q@1224|Proteobacteria,1T6T0@1236|Gammaproteobacteria,1X83F@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1453
SRR25158456_k127_3075709_15	2754.EH55_10620	0.0003381	48.0	COG4676@1|root,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarboxypepD_reg,PEGA,VWA,VWA_3
SRR25158456_k127_3075709_9	2754.EH55_10620	2.982e-10	72.0	COG4676@1|root,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarboxypepD_reg,PEGA,VWA,VWA_3
SRR25158456_k127_3075709_14	1223410.KN050846_gene1368	6.702e-05	53.0	28P2C@1|root,2ZBYG@2|Bacteria,4NMEQ@976|Bacteroidetes,1I19G@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3075709_5	1242864.D187_004044	3.485e-27	116.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_3075709_4	1287276.X752_28935	2.749e-31	130.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,43IJ1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158456_k127_3075709_1	220664.PFL_2030	3.013e-122	405.0	COG2327@1|root,COG2327@2|Bacteria,1NMK5@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
SRR25158456_k127_3075709_8	314278.NB231_05906	4.757e-21	95.0	COG2442@1|root,COG2442@2|Bacteria,1NH5R@1224|Proteobacteria,1SH9A@1236|Gammaproteobacteria,1X1ZR@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_3075709_2	639030.JHVA01000001_gene1493	1.052e-83	292.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria,2JHIX@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158456_k127_3075709_0	204669.Acid345_1576	3.604e-216	704.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria,2JHVF@204432|Acidobacteriia	204432|Acidobacteriia	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158456_k127_3075709_13	269799.Gmet_1863	8.879e-06	57.0	COG4972@1|root,COG4972@2|Bacteria,1NUYA@1224|Proteobacteria,42ZJI@68525|delta/epsilon subdivisions,2WV3A@28221|Deltaproteobacteria,43UN3@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein	pulM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158456_k127_3075709_10	204669.Acid345_1577	2.331e-09	66.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria,2JJG9@204432|Acidobacteriia	204432|Acidobacteriia	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
SRR25158456_k127_3075709_12	34839.XP_005409752.1	8.579e-06	58.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,480TD@7711|Chordata,494JZ@7742|Vertebrata,3J3CH@40674|Mammalia,35ANS@314146|Euarchontoglires,4PWQ4@9989|Rodentia	33208|Metazoa	T	vitamin D binding	COMP	GO:0001501,GO:0001968,GO:0002020,GO:0003416,GO:0003417,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005912,GO:0005924,GO:0005927,GO:0007155,GO:0007275,GO:0007517,GO:0008150,GO:0008201,GO:0008289,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010941,GO:0016043,GO:0016203,GO:0019842,GO:0019899,GO:0022610,GO:0030054,GO:0030055,GO:0030198,GO:0031012,GO:0032501,GO:0032502,GO:0032991,GO:0033627,GO:0035265,GO:0036094,GO:0040007,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043394,GO:0043395,GO:0044421,GO:0044877,GO:0046872,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048705,GO:0048731,GO:0048736,GO:0048856,GO:0050789,GO:0050794,GO:0051216,GO:0060173,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060538,GO:0060548,GO:0061061,GO:0061448,GO:0062023,GO:0065007,GO:0070161,GO:0071840,GO:0097159,GO:0097367,GO:0098868,GO:1901681	-	ko:K04659	ko04145,ko04151,ko04510,ko04512,ko05144,ko05165,map04145,map04151,map04510,map04512,map05144,map05165	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04147,ko04516	-	-	-	COMP,EGF_CA,TSP_3,TSP_C
SRR25158456_k127_3075709_3	404380.Gbem_1284	7.498e-79	294.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,42NBT@68525|delta/epsilon subdivisions,2WKAW@28221|Deltaproteobacteria,43SD0@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	type II and III secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
SRR25158456_k127_3075709_6	204669.Acid345_1998	2.145e-25	113.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158456_k127_3075709_7	1232410.KI421421_gene3657	1.266e-21	100.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,42TXR@68525|delta/epsilon subdivisions,2WQP0@28221|Deltaproteobacteria,43SPZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158456_k127_3083668_0	1411123.JQNH01000001_gene932	3.906e-121	393.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	chvD	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
SRR25158456_k127_3083668_7	378806.STAUR_3506	1.236e-07	64.0	COG1470@1|root,COG1629@1|root,COG1470@2|Bacteria,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,439J0@68525|delta/epsilon subdivisions,2X4VG@28221|Deltaproteobacteria,2YZPG@29|Myxococcales	28221|Deltaproteobacteria	P	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_3083668_1	1033743.CAES01000009_gene1881	1.143e-101	357.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26QA9@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	yknV	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158456_k127_3083668_4	1536774.H70357_34135	2.756e-71	260.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4HCG2@91061|Bacilli,26TIW@186822|Paenibacillaceae	91061|Bacilli	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
SRR25158456_k127_3083668_6	44251.PDUR_02255	1.741e-34	148.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158456_k127_3083668_5	1122182.KB903833_gene5494	3.423e-44	183.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4DAX5@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_3083668_2	518766.Rmar_1860	2.48e-86	294.0	COG3279@1|root,COG3279@2|Bacteria,4NEAH@976|Bacteroidetes,1FJ14@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158456_k127_3083668_3	518766.Rmar_1861	1.202e-74	257.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1FIPJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158456_k127_3085550_2	653733.Selin_0883	1.287e-40	158.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00338,ko:K02573	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SRR25158456_k127_3085550_0	1150621.SMUL_0519	4.708e-159	528.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2YMSC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
SRR25158456_k127_3085550_4	1051632.TPY_0858	2.526e-11	64.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,24GH5@186801|Clostridia,3WDHK@538999|Clostridiales incertae sedis	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158456_k127_3085550_1	1184267.A11Q_1950	5.22e-49	179.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2MT1A@213481|Bdellovibrionales,2WNNV@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158456_k127_3085550_3	1120948.KB903221_gene391	6.947e-15	86.0	COG0438@1|root,COG0438@2|Bacteria,2HNS7@201174|Actinobacteria,4E77U@85010|Pseudonocardiales	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_3093486_5	378806.STAUR_5515	1.585e-99	353.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,43823@68525|delta/epsilon subdivisions,2X3C5@28221|Deltaproteobacteria,2YVD0@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158456_k127_3093486_19	452637.Oter_1832	3.677e-29	126.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158456_k127_3093486_1	395961.Cyan7425_1965	1.301e-219	689.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158456_k127_3093486_3	395961.Cyan7425_1966	2.388e-176	566.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158456_k127_3093486_9	1121920.AUAU01000022_gene2445	9.915e-58	211.0	COG0697@1|root,COG0697@2|Bacteria,3Y570@57723|Acidobacteria	57723|Acidobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158456_k127_3093486_25	298655.KI912266_gene773	3.7e-08	61.0	COG4567@1|root,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158456_k127_3093486_23	1120971.AUCA01000019_gene1100	1.136e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,2780P@186823|Alicyclobacillaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_3093486_21	234267.Acid_4174	4.414e-27	114.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_3093486_14	1519464.HY22_03120	2.065e-44	167.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158456_k127_3093486_15	1121373.KB903624_gene2429	1.986e-42	176.0	COG3832@1|root,COG3832@2|Bacteria,4NT4P@976|Bacteroidetes,47R8X@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_3093486_17	1157708.KB907464_gene383	1.244e-36	142.0	COG0346@1|root,COG0346@2|Bacteria,1RHQB@1224|Proteobacteria,2VV8S@28216|Betaproteobacteria,4AHZ3@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158456_k127_3093486_6	43354.JOIJ01000002_gene4429	8.52e-84	290.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4EAXH@85010|Pseudonocardiales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158456_k127_3093486_7	398578.Daci_2533	3.278e-79	278.0	COG1737@1|root,COG1737@2|Bacteria,1NS7C@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3093486_10	234267.Acid_7656	2.212e-55	203.0	COG5397@1|root,COG5397@2|Bacteria	2|Bacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
SRR25158456_k127_3093486_0	448385.sce5477	4.088e-229	711.0	COG3055@1|root,COG3055@2|Bacteria,1QA4H@1224|Proteobacteria,434UC@68525|delta/epsilon subdivisions,2WZ59@28221|Deltaproteobacteria,2Z1D3@29|Myxococcales	28221|Deltaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_6
SRR25158456_k127_3093486_13	1144275.COCOR_04873	8.688e-45	188.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
SRR25158456_k127_3093486_11	246197.MXAN_3258	7.649e-51	190.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ccmA	-	3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107	-	-	ABC_tran
SRR25158456_k127_3093486_20	1382359.JIAL01000001_gene2251	1.946e-27	121.0	COG2386@1|root,COG2386@2|Bacteria,3Y3G1@57723|Acidobacteria,2JIEJ@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Cytochrome c-type biogenesis protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158456_k127_3093486_8	378806.STAUR_3693	2.49e-62	231.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2YVGN@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158456_k127_3093486_18	1278073.MYSTI_04690	6.436e-32	130.0	COG2332@1|root,COG2332@2|Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158456_k127_3093486_2	1278073.MYSTI_04691	1.522e-194	634.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,42P4Q@68525|delta/epsilon subdivisions,2WK5G@28221|Deltaproteobacteria,2YU4N@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158456_k127_3093486_12	215803.DB30_1964	1.679e-47	181.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2YVYE@29|Myxococcales	28221|Deltaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158456_k127_3093486_22	1242864.D187_009980	7.247e-18	95.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,43DRS@68525|delta/epsilon subdivisions,2X8U4@28221|Deltaproteobacteria,2Z0DW@29|Myxococcales	28221|Deltaproteobacteria	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158456_k127_3093486_24	1144275.COCOR_02993	3.058e-14	85.0	COG0457@1|root,COG0457@2|Bacteria	1144275.COCOR_02993|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3093486_4	1379270.AUXF01000002_gene1723	2.262e-122	419.0	COG4772@1|root,COG4772@2|Bacteria,1ZSWK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_3093486_16	861299.J421_0752	5.136e-41	159.0	COG3201@1|root,COG3201@2|Bacteria,1ZTRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Nicotinamide mononucleotide transporter	-	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
SRR25158456_k127_3101098_2	865937.Gilli_0660	8.835e-106	361.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158456_k127_3101098_1	357808.RoseRS_3910	9.285e-116	415.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2G8HW@200795|Chloroflexi,376W0@32061|Chloroflexia	32061|Chloroflexia	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
SRR25158456_k127_3101098_6	1245469.S58_46600	3.377e-26	123.0	COG4995@1|root,COG4995@2|Bacteria,1N2MN@1224|Proteobacteria,2UEN3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3101098_7	29078.XP_008138437.1	3.506e-11	76.0	COG4886@1|root,KOG4641@2759|Eukaryota,38HUG@33154|Opisthokonta,3BAQQ@33208|Metazoa,3CX3H@33213|Bilateria,4804K@7711|Chordata,490SM@7742|Vertebrata,3J4P0@40674|Mammalia,4KWWN@9397|Chiroptera	33208|Metazoa	T	Toll-like receptor 6	TLR6	GO:0001505,GO:0001774,GO:0001775,GO:0001816,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001934,GO:0002218,GO:0002221,GO:0002224,GO:0002237,GO:0002253,GO:0002274,GO:0002376,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002696,GO:0002755,GO:0002756,GO:0002757,GO:0002758,GO:0002764,GO:0002790,GO:0002791,GO:0002792,GO:0003674,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005886,GO:0005887,GO:0006355,GO:0006807,GO:0006810,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007154,GO:0007165,GO:0007250,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009306,GO:0009593,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0010942,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016045,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0032101,GO:0032103,GO:0032147,GO:0032268,GO:0032270,GO:0032490,GO:0032493,GO:0032501,GO:0032611,GO:0032612,GO:0032655,GO:0032675,GO:0032677,GO:0032680,GO:0032717,GO:0032720,GO:0032735,GO:0032755,GO:0032872,GO:0032874,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033036,GO:0033218,GO:0033674,GO:0034121,GO:0034122,GO:0034135,GO:0034136,GO:0035325,GO:0035355,GO:0035556,GO:0035663,GO:0035666,GO:0038023,GO:0038061,GO:0038124,GO:0042035,GO:0042108,GO:0042116,GO:0042133,GO:0042221,GO:0042277,GO:0042325,GO:0042327,GO:0042494,GO:0042496,GO:0042498,GO:0042742,GO:0042802,GO:0042886,GO:0043030,GO:0043032,GO:0043085,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043235,GO:0043254,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043506,GO:0043507,GO:0043549,GO:0044087,GO:0044089,GO:0044093,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045075,GO:0045084,GO:0045088,GO:0045089,GO:0045121,GO:0045184,GO:0045321,GO:0045408,GO:0045410,GO:0045428,GO:0045429,GO:0045859,GO:0045860,GO:0045937,GO:0046209,GO:0046328,GO:0046330,GO:0046903,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050663,GO:0050701,GO:0050702,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050727,GO:0050729,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050865,GO:0050867,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051090,GO:0051091,GO:0051092,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051338,GO:0051347,GO:0051606,GO:0051704,GO:0051707,GO:0051716,GO:0055094,GO:0060089,GO:0060255,GO:0061900,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070302,GO:0070304,GO:0070339,GO:0070340,GO:0070887,GO:0071216,GO:0071219,GO:0071220,GO:0071221,GO:0071310,GO:0071402,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071723,GO:0071724,GO:0071726,GO:0071900,GO:0071902,GO:0071944,GO:0072593,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0098542,GO:0098543,GO:0098581,GO:0098589,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0098857,GO:0140052,GO:1900015,GO:1900017,GO:1900225,GO:1900227,GO:1900407,GO:1900409,GO:1901214,GO:1901216,GO:1901222,GO:1901224,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533,GO:1902882,GO:1902884,GO:1903201,GO:1903203,GO:1903209,GO:1903223,GO:1903426,GO:1903428,GO:1903506,GO:1903530,GO:1903531,GO:1903555,GO:1903556,GO:1904407,GO:1904467,GO:1904468,GO:1904645,GO:1904646,GO:1904950,GO:2000112,GO:2000377,GO:2000379,GO:2000482,GO:2000483,GO:2001057,GO:2001141	-	ko:K05398,ko:K10169,ko:K10171,ko:K18808	ko04145,ko04620,ko05142,ko05152,map04145,map04620,map05142,map05152	-	-	-	ko00000,ko00001,ko04090,ko04131	-	-	-	LRRCT,LRR_4,LRR_6,LRR_8,TIR
SRR25158456_k127_3101098_0	1291050.JAGE01000001_gene2763	3.833e-225	714.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
SRR25158456_k127_3101098_4	1547437.LL06_13530	5.929e-32	139.0	COG5266@1|root,COG5266@2|Bacteria,1RA8J@1224|Proteobacteria,2U5BT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
SRR25158456_k127_3101098_3	1123360.thalar_03210	7.949e-64	240.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
SRR25158456_k127_3101098_5	379066.GAU_0215	1.022e-30	134.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158456_k127_3101098_8	1121033.AUCF01000017_gene3758	0.0002622	52.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,2JY59@204441|Rhodospirillales	28211|Alphaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158456_k127_3103755_4	234267.Acid_5252	2.066e-06	54.0	COG3829@1|root,COG3829@2|Bacteria,3Y5ZF@57723|Acidobacteria	57723|Acidobacteria	KT	PFAM helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8
SRR25158456_k127_3103755_5	1235801.C822_02023	2.687e-05	57.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,4HD9X@91061|Bacilli,3F4AK@33958|Lactobacillaceae	91061|Bacilli	S	Bacterial membrane protein YfhO	yfhO	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_3103755_3	1128421.JAGA01000003_gene3091	6.817e-28	130.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_3103755_1	314285.KT71_04350	1.968e-70	264.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158456_k127_3103755_2	1408473.JHXO01000006_gene1084	6.173e-55	200.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,2FN2K@200643|Bacteroidia	976|Bacteroidetes	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
SRR25158456_k127_3103755_0	350688.Clos_0025	1.842e-90	313.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36EK3@31979|Clostridiaceae	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158456_k127_3106701_1	1396141.BATP01000006_gene5477	7.295e-150	511.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,46TDA@74201|Verrucomicrobia,2IV8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_3106701_3	518766.Rmar_0925	8.82e-90	329.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158456_k127_3106701_2	344747.PM8797T_07337	8.497e-108	365.0	COG0591@1|root,COG0591@2|Bacteria,2IXNM@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SRR25158456_k127_3106701_5	1128421.JAGA01000003_gene2894	4.551e-48	180.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158456_k127_3106701_4	349741.Amuc_1861	1.543e-65	229.0	COG3738@1|root,COG3738@2|Bacteria,46X3M@74201|Verrucomicrobia,2IUCP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
SRR25158456_k127_3106701_0	1297742.A176_00627	0.0	1427.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158456_k127_3113068_2	760192.Halhy_4812	3.467e-10	72.0	2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3113068_0	1396141.BATP01000009_gene2656	3.056e-73	261.0	COG3361@1|root,COG3361@2|Bacteria,46X33@74201|Verrucomicrobia,2IUDI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
SRR25158456_k127_3113068_1	1123320.KB889674_gene4225	6.58e-63	229.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1,SEFIR
SRR25158456_k127_3119025_2	211165.AJLN01000153_gene709	9.572e-97	347.0	COG2274@1|root,COG2274@2|Bacteria,1G0V8@1117|Cyanobacteria,1JHH6@1189|Stigonemataceae	1117|Cyanobacteria	V	Peptidase C39 family	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158456_k127_3119025_6	1121033.AUCF01000008_gene5623	6.107e-08	67.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,2JPMM@204441|Rhodospirillales	204441|Rhodospirillales	M	HlyD family secretion protein	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
SRR25158456_k127_3119025_4	266117.Rxyl_2192	3.444e-20	104.0	2DQBG@1|root,335T7@2|Bacteria	2|Bacteria	S	Selenoprotein B glycine betaine sarcosine D-proline reductase	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRR25158456_k127_3119025_7	316274.Haur_4405	3.865e-05	49.0	2DREH@1|root,33BDY@2|Bacteria,2G9NT@200795|Chloroflexi,377SC@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3119025_1	1300345.LF41_1043	5.011e-232	736.0	COG4206@1|root,COG4206@2|Bacteria,1QUUI@1224|Proteobacteria	1224|Proteobacteria	H	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug
SRR25158456_k127_3119025_3	1192034.CAP_3656	1.641e-67	260.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria,2YV2M@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158456_k127_3119025_0	575540.Isop_2661	5.653e-250	790.0	COG3387@1|root,COG3387@2|Bacteria,2IXUW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158456_k127_3119025_5	1218084.BBJK01000017_gene1839	3.877e-18	100.0	COG2909@1|root,COG4995@1|root,COG2909@2|Bacteria,COG4995@2|Bacteria,1QUP3@1224|Proteobacteria,2VM2I@28216|Betaproteobacteria,1K6DW@119060|Burkholderiaceae	28216|Betaproteobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16
SRR25158456_k127_3120086_2	1123242.JH636435_gene2634	2.485e-94	316.0	COG0656@1|root,COG0656@2|Bacteria,2IWVI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158456_k127_3120086_3	65497.JODV01000012_gene2337	1.389e-21	104.0	COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria,4E3Z1@85010|Pseudonocardiales	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158456_k127_3120086_4	1458275.AZ34_10270	2.903e-15	83.0	COG3000@1|root,COG3000@2|Bacteria,1N39U@1224|Proteobacteria,2VWC0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158456_k127_3120086_1	1379698.RBG1_1C00001G0607	1.288e-145	490.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
SRR25158456_k127_3120086_0	1192034.CAP_7724	1.17e-145	467.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42Z4J@68525|delta/epsilon subdivisions,2WUHY@28221|Deltaproteobacteria,2YWQR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158456_k127_3121849_5	1150621.SMUL_0604	4.36e-15	79.0	COG4634@1|root,COG4634@2|Bacteria,1NAN6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3121849_4	41431.PCC8801_1888	7.501e-31	122.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria,3KIU5@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_3121849_3	1318628.MARLIPOL_03970	8.697e-35	150.0	2EGRV@1|root,33AI1@2|Bacteria,1NJQM@1224|Proteobacteria,1SQI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3121849_2	1385515.N791_07785	3.885e-77	282.0	29NMG@1|root,309JE@2|Bacteria,1RDNI@1224|Proteobacteria,1SMEH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3121849_1	246197.MXAN_1340	1.396e-107	366.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,42MWP@68525|delta/epsilon subdivisions,2WKGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158456_k127_3121849_0	1297742.A176_07068	1.975e-276	887.0	COG4403@1|root,COG4403@2|Bacteria,1R8VP@1224|Proteobacteria,432AY@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	Domain of unknown function (DUF4135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
SRR25158456_k127_3121849_7	1089545.KB913037_gene9141	8.978e-07	54.0	2ENJF@1|root,33G6U@2|Bacteria	2|Bacteria	S	TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3128807_4	861299.J421_5885	1.672e-97	345.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1ZUID@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_3128807_13	443143.GM18_0461	1.117e-14	81.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,42ZR0@68525|delta/epsilon subdivisions,2WT3B@28221|Deltaproteobacteria,43UQ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_3128807_7	204669.Acid345_0303	8.774e-56	198.0	COG1764@1|root,COG1764@2|Bacteria,3Y4TU@57723|Acidobacteria,2JJIC@204432|Acidobacteriia	204432|Acidobacteriia	O	peroxiredoxin, OsmC subfamily	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158456_k127_3128807_6	883126.HMPREF9710_04155	1.903e-59	214.0	COG3932@1|root,COG3932@2|Bacteria,1REE4@1224|Proteobacteria,2VXYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
SRR25158456_k127_3128807_8	671143.DAMO_2689	1.005e-55	202.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158456_k127_3128807_3	247490.KSU1_D0315	6.349e-104	372.0	COG1007@1|root,COG1007@2|Bacteria,2IXC6@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158456_k127_3128807_1	247490.KSU1_D0316	2.457e-176	567.0	COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes	203682|Planctomycetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158456_k127_3128807_0	1125863.JAFN01000001_gene2410	1.352e-192	621.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158456_k127_3128807_11	1173026.Glo7428_2958	9.176e-19	91.0	2DM1K@1|root,31BCJ@2|Bacteria,1G6WG@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3128807_9	398767.Glov_3128	1.304e-29	129.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158456_k127_3128807_10	443143.GM18_4381	1.335e-26	116.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42V5H@68525|delta/epsilon subdivisions,2WQF4@28221|Deltaproteobacteria,43USM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ-1	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158456_k127_3128807_5	517418.Ctha_0603	7.781e-96	325.0	COG1005@1|root,COG1005@2|Bacteria,1FF0G@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158456_k127_3128807_2	671143.DAMO_1616	1.034e-106	364.0	COG1034@1|root,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SRR25158456_k127_3128807_12	639283.Snov_2789	4.939e-16	88.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,3EZ6E@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	PPIC-type PPIASE domain	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
SRR25158456_k127_313087_1	497964.CfE428DRAFT_2993	2.419e-110	383.0	COG5002@1|root,COG5002@2|Bacteria,46Z3U@74201|Verrucomicrobia	74201|Verrucomicrobia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
SRR25158456_k127_313087_2	382464.ABSI01000012_gene2139	1.604e-25	125.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,VPEP
SRR25158456_k127_313087_3	497964.CfE428DRAFT_5515	1.596e-06	63.0	COG0265@1|root,COG4733@1|root,COG0265@2|Bacteria,COG4733@2|Bacteria,46Z8W@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158456_k127_313087_0	1122604.JONR01000025_gene4602	3.127e-118	402.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1SHX7@1236|Gammaproteobacteria,1X4MN@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158456_k127_3140294_10	204669.Acid345_4247	3.461e-09	68.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y4TR@57723|Acidobacteria,2JN9G@204432|Acidobacteriia	204432|Acidobacteriia	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_3140294_6	543728.Vapar_3152	1.719e-22	107.0	COG2207@1|root,COG2207@2|Bacteria,1R5XY@1224|Proteobacteria,2VS8G@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K05372	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding_2,HTH_18
SRR25158456_k127_3140294_4	926560.KE387027_gene526	1.557e-38	155.0	COG0457@1|root,COG0457@2|Bacteria	926560.KE387027_gene526|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3140294_9	504472.Slin_0587	6.011e-13	80.0	COG0457@1|root,COG0457@2|Bacteria	504472.Slin_0587|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3140294_5	870187.Thini_1715	7.055e-23	113.0	COG4916@1|root,COG4916@2|Bacteria,1QWGX@1224|Proteobacteria	1224|Proteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_3140294_3	686340.Metal_3155	3.664e-45	176.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales	135618|Methylococcales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
SRR25158456_k127_3140294_0	234267.Acid_3259	3.385e-305	949.0	COG1297@1|root,COG1297@2|Bacteria,3Y3SD@57723|Acidobacteria	57723|Acidobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
SRR25158456_k127_3140294_11	426117.M446_1092	1.097e-05	59.0	COG1266@1|root,COG1266@2|Bacteria,1NID0@1224|Proteobacteria,2UZ8R@28211|Alphaproteobacteria,1JTVG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158456_k127_3140294_8	1096546.WYO_0651	3.534e-15	88.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158456_k127_3140294_2	1121920.AUAU01000012_gene2631	7.267e-59	233.0	COG1629@1|root,COG4771@2|Bacteria,3Y3ZU@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_3140294_1	933262.AXAM01000026_gene3074	1.189e-111	375.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2MICK@213118|Desulfobacterales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_3140294_7	1052684.PPM_2175	8.043e-18	84.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,26R6I@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_3143987_1	264462.Bd1027	1.061e-10	62.0	COG2605@1|root,COG2605@2|Bacteria,1Q1GI@1224|Proteobacteria,42TJZ@68525|delta/epsilon subdivisions,2MT41@213481|Bdellovibrionales,2WQNP@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158456_k127_3143987_0	525897.Dbac_2030	1.325e-75	270.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158456_k127_3144824_3	983917.RGE_09050	1.568e-63	228.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2VQ1R@28216|Betaproteobacteria,1KNEH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	baeR	-	-	ko:K07664	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_3144824_5	326427.Cagg_2708	1.595e-46	180.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158456_k127_3144824_4	316067.Geob_3031	8.866e-56	205.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,43SFX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
SRR25158456_k127_3144824_6	1485545.JQLW01000010_gene1652	1.207e-39	163.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	fadL	GO:0003674,GO:0005215,GO:0005319,GO:0005324,GO:0005342,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0009279,GO:0010876,GO:0015075,GO:0015245,GO:0015267,GO:0015288,GO:0015318,GO:0015483,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022834,GO:0022836,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0034220,GO:0044462,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	iECs_1301.ECs3227,iG2583_1286.G2583_2880,iZ_1308.Z3608	Toluene_X
SRR25158456_k127_3144824_0	404589.Anae109_0984	1.07e-86	312.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2YX41@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158456_k127_3144824_1	1177928.TH2_03650	6.693e-67	237.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,2JQU8@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	chvI	-	-	ko:K14981	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_3144824_2	1380391.JIAS01000014_gene2095	9.766e-65	241.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,2TWBW@28211|Alphaproteobacteria,2JPN9@204441|Rhodospirillales	204441|Rhodospirillales	T	Stimulus-sensing domain	chvG	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
SRR25158456_k127_3144824_7	2074.JNYD01000015_gene4461	6.176e-17	95.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4E1BA@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158456_k127_3153495_0	671143.DAMO_2624	8.467e-211	666.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158456_k127_3153495_3	1174528.JH992888_gene269	3.2e-07	61.0	2EK29@1|root,33DSQ@2|Bacteria,1GFW5@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3153495_1	1382356.JQMP01000001_gene1206	3.804e-36	146.0	COG1268@1|root,COG1268@2|Bacteria,2GBUZ@200795|Chloroflexi,27YWE@189775|Thermomicrobia	189775|Thermomicrobia	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158456_k127_3153495_2	926560.KE387023_gene3841	8.948e-23	102.0	COG0120@1|root,COG0120@2|Bacteria,1WIR4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158456_k127_3163108_19	1336233.JAEH01000002_gene1343	1.457e-25	111.0	2DKWY@1|root,30NX3@2|Bacteria,1RBMB@1224|Proteobacteria,1S5SW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3163108_4	56780.SYN_00437	4.345e-129	425.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MQ7W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158456_k127_3163108_2	404380.Gbem_0496	6.324e-131	429.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158456_k127_3163108_22	297246.lpp2664	9.546e-07	61.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1JDVB@118969|Legionellales	118969|Legionellales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158456_k127_3163108_6	1379698.RBG1_1C00001G0397	1.829e-116	390.0	COG0773@1|root,COG0773@2|Bacteria,2NNPU@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093,iJN678.murC	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158456_k127_3163108_11	1144275.COCOR_06095	2.279e-87	301.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWWJ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158456_k127_3163108_13	1382359.JIAL01000001_gene1976	1.536e-84	294.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158456_k127_3163108_10	1382359.JIAL01000001_gene1975	3.455e-98	336.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158456_k127_3163108_7	1122929.KB908217_gene273	1.646e-115	400.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158456_k127_3163108_9	639030.JHVA01000001_gene1388	3.116e-98	338.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria,2JHW4@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158456_k127_3163108_5	1278073.MYSTI_06199	1.474e-121	408.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158456_k127_3163108_3	330214.NIDE0755	1.552e-130	442.0	COG0768@1|root,COG0768@2|Bacteria,3J0FH@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158456_k127_3163108_12	290397.Adeh_3763	8.936e-86	293.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2YUXX@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158456_k127_3163108_18	1382359.JIAL01000001_gene1949	5.935e-37	145.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158456_k127_3163108_17	1408254.T458_19155	7.327e-38	149.0	COG3339@1|root,COG3339@2|Bacteria,1V6NW@1239|Firmicutes,4HJQR@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158456_k127_3163108_0	867845.KI911784_gene896	0.0	1341.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,375DP@32061|Chloroflexia	32061|Chloroflexia	F	Carbamoyl-phosphate synthetase large chain domain protein	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158456_k127_3163108_14	317936.Nos7107_3191	1.55e-75	260.0	COG1028@1|root,COG1028@2|Bacteria,1G2FK@1117|Cyanobacteria	1117|Cyanobacteria	IQ	PFAM short chain dehydrogenase	-	-	1.1.1.206	ko:K08081	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R02832	RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158456_k127_3163108_8	1267534.KB906759_gene1844	3.038e-112	376.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158456_k127_3163108_21	671143.DAMO_1561	1.598e-18	98.0	COG4856@1|root,COG4856@2|Bacteria,2NQ44@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	dacA	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158456_k127_3163108_16	1123376.AUIU01000011_gene928	7.008e-53	196.0	COG1624@1|root,COG1624@2|Bacteria,3J0XP@40117|Nitrospirae	40117|Nitrospirae	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158456_k127_3163108_15	999549.KI421513_gene2634	7.705e-72	251.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,27ZKV@191028|Leisingera	28211|Alphaproteobacteria	H	Pterin binding enzyme	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158456_k127_3163108_1	316274.Haur_0837	9.021e-160	523.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi,374XF@32061|Chloroflexia	32061|Chloroflexia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158456_k127_3163108_20	1358423.N180_16585	4.054e-24	119.0	COG1235@1|root,COG1235@2|Bacteria,4NDVI@976|Bacteroidetes,1IWIM@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase	vicX	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
SRR25158456_k127_3168314_0	1321786.HMPREF1992_01318	2.955e-135	443.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4H39S@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158456_k127_3168314_3	742767.HMPREF9456_01429	2.454e-18	89.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,2FTSX@200643|Bacteroidia,22YDJ@171551|Porphyromonadaceae	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
SRR25158456_k127_3168314_1	1082705.JIBP01000017_gene782	6.946e-56	204.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_2618	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158456_k127_3168314_2	1382359.JIAL01000001_gene404	8.933e-29	122.0	COG1595@1|root,COG1595@2|Bacteria,3Y87A@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158456_k127_3170986_1	1198452.Jab_2c00030	0.0	1244.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,473K1@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Linear gramicidin synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_3170986_0	406818.XBJ1_2151	0.0	2867.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	ko:K16125	ko01054,map01054	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_3170986_2	84531.JMTZ01000092_gene1613	3.018e-195	629.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria,1X3AB@135614|Xanthomonadales	135614|Xanthomonadales	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_3171766_6	521674.Plim_1896	2.686e-33	134.0	COG0394@1|root,COG0394@2|Bacteria,2J115@203682|Planctomycetes	203682|Planctomycetes	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158456_k127_3171766_3	861299.J421_3958	7.586e-55	199.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyrid_ox_like
SRR25158456_k127_3171766_1	357808.RoseRS_0423	3.778e-77	263.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158456_k127_3171766_7	1124780.ANNU01000059_gene874	3.667e-30	132.0	COG1051@1|root,COG1051@2|Bacteria,4NU4A@976|Bacteroidetes,47RFK@768503|Cytophagia	976|Bacteroidetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158456_k127_3171766_5	204669.Acid345_2222	1.016e-36	145.0	COG2322@1|root,COG2322@2|Bacteria,3Y4U9@57723|Acidobacteria,2JJKU@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
SRR25158456_k127_3171766_2	1282360.ABAC460_18820	1.41e-62	218.0	COG1487@1|root,COG1487@2|Bacteria,1RD5N@1224|Proteobacteria,2U73N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158456_k127_3171766_9	107636.JQNK01000009_gene1483	5.355e-26	109.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_3171766_4	1116472.MGMO_72c00090	4.101e-43	182.0	COG1629@1|root,COG4771@2|Bacteria,1MX42@1224|Proteobacteria,1RQ2K@1236|Gammaproteobacteria,1XFH2@135618|Methylococcales	135618|Methylococcales	P	TonB dependent receptor	-	-	-	ko:K16087	-	-	-	-	ko00000,ko02000	1.B.14.2	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_3171766_8	357808.RoseRS_1471	1.81e-27	118.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_3171766_10	234267.Acid_5658	7.731e-25	117.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3171766_13	2002.JOEQ01000042_gene5939	1.14e-06	61.0	COG2319@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3629@2|Bacteria,2GJN3@201174|Actinobacteria,4EMXK@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,WD40
SRR25158456_k127_3171766_0	682795.AciX8_4273	8.592e-106	375.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria,2JK1Q@204432|Acidobacteriia	204432|Acidobacteriia	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_3171766_12	1267534.KB906757_gene1011	9.393e-13	79.0	28U6K@1|root,2ZGCA@2|Bacteria,3Y8UV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3171766_11	1382359.JIAL01000001_gene404	1.534e-22	107.0	COG1595@1|root,COG1595@2|Bacteria,3Y87A@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158456_k127_3172618_2	1303518.CCALI_02307	1.677e-15	82.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,Thioredoxin_7
SRR25158456_k127_3172618_1	926569.ANT_04550	3.672e-53	196.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158456_k127_3172618_0	1207058.L53_11565	4.188e-54	212.0	COG3108@1|root,COG3108@2|Bacteria,1RAMQ@1224|Proteobacteria,2UQDA@28211|Alphaproteobacteria,43WJZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
SRR25158456_k127_3178649_1	661478.OP10G_3531	3.116e-80	274.0	COG1028@1|root,COG1028@2|Bacteria	661478.OP10G_3531|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR25158456_k127_3178649_4	471854.Dfer_3931	2.955e-48	180.0	COG1898@1|root,COG1898@2|Bacteria,4NPVI@976|Bacteroidetes,47UPU@768503|Cytophagia	976|Bacteroidetes	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158456_k127_3178649_3	671143.DAMO_0910	5.214e-61	220.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
SRR25158456_k127_3178649_2	869210.Marky_0691	6.037e-80	275.0	COG2084@1|root,COG2084@2|Bacteria,1WIBK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM NAD binding domain of 6-phosphogluconate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158456_k127_3178649_0	1449976.KALB_1389	6.884e-138	452.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,4DXWC@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158456_k127_3180399_1	1232410.KI421421_gene3667	5.904e-59	217.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43U3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158456_k127_3180399_0	215803.DB30_1825	1.622e-113	404.0	COG0840@1|root,COG4166@1|root,COG0840@2|Bacteria,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,43BXR@68525|delta/epsilon subdivisions,2X1YS@28221|Deltaproteobacteria,2YYSK@29|Myxococcales	28221|Deltaproteobacteria	ENT	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,SBP_bac_5
SRR25158456_k127_3180399_4	28115.HR11_00825	4.845e-12	76.0	COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,2FP7S@200643|Bacteroidia,22XCP@171551|Porphyromonadaceae	976|Bacteroidetes	EG	membrane	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158456_k127_3180399_3	234267.Acid_7247	1.311e-28	124.0	COG1595@1|root,COG1595@2|Bacteria,3Y815@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_3180574_0	1540257.JQMW01000011_gene1612	1.784e-127	422.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,36E24@31979|Clostridiaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158456_k127_3180574_12	247490.KSU1_C0551	9.889e-05	48.0	2C6B2@1|root,335GA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3180574_7	1173027.Mic7113_4931	4.157e-21	95.0	COG2929@1|root,COG2929@2|Bacteria,1G7VS@1117|Cyanobacteria,1HHKU@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR25158456_k127_3180574_2	1122611.KB903957_gene87	1.52e-109	375.0	COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria,4EM6A@85012|Streptosporangiales	201174|Actinobacteria	M	Ami_2	amiA1	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158456_k127_3180574_1	1278073.MYSTI_06301	5.585e-124	410.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158456_k127_3180574_3	1125863.JAFN01000001_gene2317	8.941e-93	310.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
SRR25158456_k127_3180574_11	96561.Dole_3269	1.979e-10	62.0	2CCSR@1|root,32K43@2|Bacteria,1QJ8W@1224|Proteobacteria,43A9D@68525|delta/epsilon subdivisions,2X0VC@28221|Deltaproteobacteria,2MPDZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158456_k127_3180574_4	330214.NIDE0244	7.477e-88	297.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158456_k127_3180574_5	639282.DEFDS_1935	2.389e-43	161.0	COG0346@1|root,COG0346@2|Bacteria,2GFMK@200930|Deferribacteres	200930|Deferribacteres	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158456_k127_3180574_10	204669.Acid345_3996	2.438e-12	76.0	2CDNF@1|root,2ZTQP@2|Bacteria,3Y955@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3180574_6	1125718.HMPREF1318_2595	2.208e-23	113.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4D3N6@85005|Actinomycetales	201174|Actinobacteria	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158456_k127_3180574_8	309801.trd_1801	9.112e-17	95.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_3180574_9	316274.Haur_3849	5.777e-15	90.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_3189142_21	1121935.AQXX01000120_gene4879	8.333e-10	64.0	2EGQV@1|root,33AH0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3189142_6	246197.MXAN_3854	4.829e-80	293.0	COG0671@1|root,COG1562@1|root,COG0671@2|Bacteria,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	ynbD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.5.1.32,2.5.1.99	ko:K02291,ko:K18163	ko00906,ko01062,ko01100,ko01110,ko04714,map00906,map01062,map01100,map01110,map04714	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	DSPc,PAP2_3,SQS_PSY
SRR25158456_k127_3189142_3	483219.LILAB_27460	2.292e-97	340.0	COG3239@1|root,COG3239@2|Bacteria,1R3Y2@1224|Proteobacteria,434KY@68525|delta/epsilon subdivisions,2WYYD@28221|Deltaproteobacteria,2Z0X8@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158456_k127_3189142_12	1144275.COCOR_02776	1.202e-47	190.0	COG4875@1|root,COG4875@2|Bacteria	2|Bacteria	IQ	SnoaL-like domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	CaMKII_AD,DUF4440,SnoaL_2,SnoaL_3
SRR25158456_k127_3189142_9	483219.LILAB_27465	1.383e-58	217.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,437H0@68525|delta/epsilon subdivisions,2X2QC@28221|Deltaproteobacteria,2YXMK@29|Myxococcales	28221|Deltaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158456_k127_3189142_14	1300345.LF41_1012	2.101e-41	168.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_2,Abhydrolase_4,Esterase
SRR25158456_k127_3189142_15	518766.Rmar_0611	2.122e-34	141.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158456_k127_3189142_2	404380.Gbem_2236	7.713e-115	394.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR25158456_k127_3189142_4	388413.ALPR1_05490	5.69e-95	324.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158456_k127_3189142_7	1210884.HG799462_gene9164	2.186e-76	281.0	COG1538@1|root,COG1538@2|Bacteria,2IZB2@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158456_k127_3189142_0	247490.KSU1_C0527	1.564e-175	559.0	COG2132@1|root,COG2132@2|Bacteria,2IX3N@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158456_k127_3189142_11	278963.ATWD01000001_gene2439	2.1e-53	195.0	COG2010@1|root,COG2010@2|Bacteria,3Y650@57723|Acidobacteria,2JKDC@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3,Paired_CXXCH_1
SRR25158456_k127_3189142_5	331869.BAL199_17133	1.615e-87	301.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2TSR9@28211|Alphaproteobacteria,4BSKZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,1.5.1.1,4.3.1.12	ko:K01750,ko:K19244,ko:K19743	ko00250,ko00310,ko00330,ko00430,ko00960,ko01100,ko01110,ko01130,ko01230,map00250,map00310,map00330,map00430,map00960,map01100,map01110,map01130,map01230	-	R00396,R00671,R01246,R01249,R02201,R02203	RC00008,RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158456_k127_3189142_19	196162.Noca_1533	2.845e-17	93.0	COG4275@1|root,COG4275@2|Bacteria,2IK0B@201174|Actinobacteria,4DUQR@85009|Propionibacteriales	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158456_k127_3189142_22	485913.Krac_10504	3.284e-06	58.0	COG4275@1|root,COG4275@2|Bacteria	2|Bacteria	S	Chromate resistance exported protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158456_k127_3189142_18	234267.Acid_6891	1.902e-17	87.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
SRR25158456_k127_3189142_1	977880.RALTA_B1525	6.258e-115	396.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,1K55C@119060|Burkholderiaceae	28216|Betaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158456_k127_3189142_8	1297865.APJD01000003_gene6294	6.171e-67	251.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,3JVEM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158456_k127_3189142_17	234267.Acid_1757	3.418e-29	124.0	COG0789@1|root,COG0789@2|Bacteria,3Y5XK@57723|Acidobacteria	57723|Acidobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind
SRR25158456_k127_3189142_16	204669.Acid345_0986	1.163e-32	140.0	COG3245@1|root,COG3245@2|Bacteria,3Y5B1@57723|Acidobacteria,2JN9F@204432|Acidobacteriia	204432|Acidobacteriia	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3189142_10	1121272.KB903290_gene4747	5.356e-58	212.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3189142_20	272134.KB731324_gene2240	5.382e-12	74.0	COG0277@1|root,COG0277@2|Bacteria,1G6C2@1117|Cyanobacteria,1HDSK@1150|Oscillatoriales	1117|Cyanobacteria	C	FAD binding domain	-	-	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,BBE,Cytokin-bind,FAD_binding_4
SRR25158456_k127_3189142_13	1157634.KB912993_gene1263	2.951e-42	171.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158456_k127_3200805_0	502025.Hoch_3511	3.156e-10	74.0	COG4932@1|root,COG4932@2|Bacteria,1PF83@1224|Proteobacteria,430QE@68525|delta/epsilon subdivisions,2WVYF@28221|Deltaproteobacteria,2Z1TZ@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158456_k127_3201740_5	1270193.JARP01000006_gene1695	9.668e-45	172.0	COG0708@1|root,COG0708@2|Bacteria,4NF57@976|Bacteroidetes,1I0AN@117743|Flavobacteriia,2NT27@237|Flavobacterium	976|Bacteroidetes	L	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158456_k127_3201740_7	509190.Cseg_0378	1.286e-27	116.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,2UFNC@28211|Alphaproteobacteria,2KJ5W@204458|Caulobacterales	204458|Caulobacterales	K	PFAM TfoX domain protein	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
SRR25158456_k127_3201740_3	378806.STAUR_2045	7.426e-67	258.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YXT4@29|Myxococcales	28221|Deltaproteobacteria	S	AAA-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_35,Pkinase,WD40
SRR25158456_k127_3201740_8	388399.SSE37_11079	1.153e-16	94.0	2DF81@1|root,32U4X@2|Bacteria,1NFWW@1224|Proteobacteria,2UCPH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3201740_1	326427.Cagg_0668	2.236e-69	251.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SRR25158456_k127_3201740_10	526222.Desal_0285	1.378e-06	53.0	COG1225@1|root,COG1225@2|Bacteria,1N9JS@1224|Proteobacteria,42R82@68525|delta/epsilon subdivisions,2WMVA@28221|Deltaproteobacteria,2MBM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158456_k127_3201740_9	1150474.JQJI01000054_gene1405	1.464e-14	77.0	COG1225@1|root,COG1225@2|Bacteria,2GD13@200918|Thermotogae	200918|Thermotogae	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158456_k127_3201740_2	1042377.AFPJ01000034_gene2428	3.689e-68	264.0	COG1404@1|root,COG5183@1|root,COG1404@2|Bacteria,COG5183@2|Bacteria	2|Bacteria	A	chlorophyll binding	isp	-	-	ko:K13275,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PRC,Peptidase_S8
SRR25158456_k127_3201740_6	1226994.AMZB01000118_gene3179	8.833e-37	144.0	COG2018@1|root,COG2018@2|Bacteria,1QV3M@1224|Proteobacteria,1T270@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3201740_11	1123256.KB907925_gene1045	0.0004677	50.0	COG3829@1|root,COG3829@2|Bacteria,1QZHD@1224|Proteobacteria,1S631@1236|Gammaproteobacteria,1X91E@135614|Xanthomonadales	135614|Xanthomonadales	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3201740_4	880073.Calab_3013	2.422e-45	179.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
SRR25158456_k127_3201740_0	1121920.AUAU01000022_gene2487	4.541e-73	253.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_321626_13	1131813.AQVT01000001_gene2803	3.452e-18	92.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,1JTCK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158456_k127_321626_6	1144275.COCOR_00645	6.695e-87	313.0	COG4395@1|root,COG4395@2|Bacteria	2|Bacteria	S	Tim44	MA20_24770	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	Tim44
SRR25158456_k127_321626_8	1035839.AFNK01000003_gene283	8.54e-60	226.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1Y7MK@135625|Pasteurellales	135625|Pasteurellales	GM	ABC transporter ATP binding subunit of Bacteria UniRef RepID Q9AQB5_AGGAC	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran
SRR25158456_k127_321626_10	411471.SUBVAR_06076	3.948e-44	182.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
SRR25158456_k127_321626_14	883126.HMPREF9710_00650	2.756e-14	85.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,473D4@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRR25158456_k127_321626_15	243233.MCA1434	4.729e-08	66.0	COG1215@1|root,COG1215@2|Bacteria,1PU38@1224|Proteobacteria,1RUPG@1236|Gammaproteobacteria,1XGIH@135618|Methylococcales	135618|Methylococcales	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158456_k127_321626_1	862908.BMS_2402	4.779e-198	632.0	COG1816@1|root,COG1816@2|Bacteria,1R7EK@1224|Proteobacteria,42MHV@68525|delta/epsilon subdivisions,2MSQX@213481|Bdellovibrionales,2WMI4@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Adenosine/AMP deaminase	-	-	-	-	-	-	-	-	-	-	-	-	A_deaminase
SRR25158456_k127_321626_2	525904.Tter_2662	2.069e-159	507.0	COG2267@1|root,COG2267@2|Bacteria,2NRKH@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	fpaP	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158456_k127_321626_5	41431.PCC8801_0005	5.364e-100	334.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
SRR25158456_k127_321626_3	1384056.N787_06630	1.472e-125	413.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,1T613@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158456_k127_321626_16	1385514.N782_00640	0.0001191	50.0	2FDUU@1|root,345VF@2|Bacteria,1VYPA@1239|Firmicutes,4HZAR@91061|Bacilli,2YBNW@289201|Pontibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_321626_0	1278073.MYSTI_02641	0.0	1069.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2X6WF@28221|Deltaproteobacteria,2YWNJ@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158456_k127_321626_4	296591.Bpro_4755	3.566e-103	339.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2VHS8@28216|Betaproteobacteria,4ACWG@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158456_k127_321626_7	1079986.JH164838_gene4303	3.14e-71	248.0	COG0666@1|root,COG0666@2|Bacteria,2I9A2@201174|Actinobacteria	201174|Actinobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
SRR25158456_k127_321626_11	1506583.JQJY01000008_gene3871	3.351e-42	166.0	COG5478@1|root,COG5478@2|Bacteria,4NQU8@976|Bacteroidetes,1I21P@117743|Flavobacteriia,2NVZS@237|Flavobacterium	976|Bacteroidetes	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SRR25158456_k127_321626_12	215803.DB30_3931	9.757e-40	154.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
SRR25158456_k127_321626_9	523791.Kkor_1131	3.684e-49	186.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yijE_3	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158456_k127_3218086_1	671143.DAMO_2095	1.311e-78	279.0	COG0744@1|root,COG0744@2|Bacteria,2NNMB@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158456_k127_3218086_4	883.DvMF_2059	0.0003759	47.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,434BN@68525|delta/epsilon subdivisions,2WWTS@28221|Deltaproteobacteria,2ME3X@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3218086_2	234267.Acid_6834	2.126e-65	241.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_3218086_0	497964.CfE428DRAFT_0230	1.801e-164	549.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,46TGZ@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_3218086_3	1198452.Jab_2c27390	3.433e-46	192.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VH1X@28216|Betaproteobacteria,478YK@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1,PAS_3,Reg_prop,Y_Y_Y
SRR25158456_k127_3219728_3	649747.HMPREF0083_00832	3.645e-44	171.0	COG1073@1|root,COG1073@2|Bacteria,1V1RV@1239|Firmicutes,4HGDR@91061|Bacilli,26QPZ@186822|Paenibacillaceae	91061|Bacilli	S	Lysophospholipase	M1-904	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DLH,Hydrolase_4
SRR25158456_k127_3219728_0	861299.J421_1936	3.073e-235	743.0	COG3158@1|root,COG3158@2|Bacteria,1ZTCK@142182|Gemmatimonadetes	2|Bacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158456_k127_3219728_5	446466.Cfla_3552	8.675e-29	128.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158456_k127_3219728_2	1169152.AXVD01000003_gene4660	3.08e-48	193.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4FUQS@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_3219728_4	1121920.AUAU01000013_gene1687	6.231e-44	184.0	COG0515@1|root,COG0515@2|Bacteria	1121920.AUAU01000013_gene1687|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3219728_6	1127673.GLIP_1743	3.945e-27	129.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,1S516@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MTH538 TIR-like domain (DUF1863)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1863,WD40
SRR25158456_k127_3219728_1	1131269.AQVV01000013_gene1720	1.827e-101	346.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_3219728_7	1121438.JNJA01000021_gene1340	1.803e-17	93.0	COG1216@1|root,COG1216@2|Bacteria,1R11B@1224|Proteobacteria,43D5D@68525|delta/epsilon subdivisions,2X8C3@28221|Deltaproteobacteria,2MA1N@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
SRR25158456_k127_3222913_2	485913.Krac_10454	3.979e-14	86.0	COG1672@1|root,COG2909@1|root,COG3591@1|root,COG1672@2|Bacteria,COG2909@2|Bacteria,COG3591@2|Bacteria,2G8QK@200795|Chloroflexi	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,Abhydrolase_1,DUF234,GerE,Trans_reg_C,Trypsin_2
SRR25158456_k127_3222913_1	118168.MC7420_4100	1.982e-47	193.0	COG3591@1|root,COG3591@2|Bacteria,1G4N7@1117|Cyanobacteria,1HCM7@1150|Oscillatoriales	1117|Cyanobacteria	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158456_k127_3222913_0	502025.Hoch_0166	9.008e-121	394.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158456_k127_3224384_1	595536.ADVE02000001_gene850	4.222e-171	556.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,36Y0V@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_3224384_4	1144275.COCOR_00985	2.662e-51	196.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,42NVY@68525|delta/epsilon subdivisions,2WKWM@28221|Deltaproteobacteria,2YU8T@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158456_k127_3224384_0	204669.Acid345_3065	5.364e-201	643.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,3Y5CQ@57723|Acidobacteria,2JKVX@204432|Acidobacteriia	204432|Acidobacteriia	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
SRR25158456_k127_3224384_3	1384056.N787_01780	6.604e-57	207.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3224384_2	1499967.BAYZ01000105_gene3512	1.455e-99	334.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158456_k127_3224384_5	330214.NIDE0343	4.093e-25	117.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158456_k127_3225900_1	429009.Adeg_0450	3.545e-42	167.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,42F43@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Galactose-1-phosphate uridyl transferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,DUF4931,GalP_UDP_tr_C,GalP_UDP_transf
SRR25158456_k127_3225900_0	234267.Acid_5939	3.146e-82	282.0	COG1807@1|root,COG1807@2|Bacteria,3Y383@57723|Acidobacteria	57723|Acidobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_3235169_1	929556.Solca_1355	1.863e-53	192.0	COG0662@1|root,COG0662@2|Bacteria,4NQIP@976|Bacteroidetes,1IZZH@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158456_k127_3235169_3	1278073.MYSTI_07079	8.481e-20	104.0	2AQ29@1|root,31F7C@2|Bacteria,1NHC1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3235169_2	1411123.JQNH01000001_gene1550	7.99e-26	125.0	2DZ1Z@1|root,34C5P@2|Bacteria,1P6W6@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158456_k127_3235169_0	1286093.C266_25740	4.4e-73	259.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2WFNZ@28216|Betaproteobacteria,1KI4E@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
SRR25158456_k127_3235169_4	158189.SpiBuddy_2854	5.254e-09	61.0	COG0048@1|root,COG0048@2|Bacteria,2J7NE@203691|Spirochaetes	203691|Spirochaetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158456_k127_3235479_2	497965.Cyan7822_3673	2.317e-101	343.0	COG1104@1|root,COG1104@2|Bacteria,1G0D5@1117|Cyanobacteria,3KG9T@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158456_k127_3235479_7	215803.DB30_7610	1.739e-07	64.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158456_k127_3235479_5	1121124.JNIX01000013_gene1550	3.533e-27	115.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3235479_6	1449353.JQMQ01000004_gene6211	3.327e-17	93.0	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria,2NF54@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158456_k127_3235479_4	1121033.AUCF01000019_gene3730	5.007e-46	171.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2U7NP@28211|Alphaproteobacteria,2JS9M@204441|Rhodospirillales	204441|Rhodospirillales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158456_k127_3235479_3	1380394.JADL01000001_gene3101	7.868e-80	297.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,2JV5D@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1
SRR25158456_k127_3235479_0	1123054.KB907731_gene2659	4.512e-180	574.0	COG0024@1|root,COG0024@2|Bacteria,1QXY6@1224|Proteobacteria,1T3K3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	xaa-pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SRR25158456_k127_3235479_1	1396141.BATP01000003_gene5228	3.166e-126	415.0	COG0451@1|root,COG0451@2|Bacteria,46XPQ@74201|Verrucomicrobia,2IWC3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3235893_1	204669.Acid345_1620	1.469e-92	309.0	COG1136@1|root,COG1136@2|Bacteria,3Y4A6@57723|Acidobacteria,2JMVQ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_3235893_3	913325.N799_04710	1.193e-61	232.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,1X3MX@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_3235893_2	204669.Acid345_1618	3.92e-87	302.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_3235893_0	518766.Rmar_0925	2.092e-131	442.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158456_k127_3235893_5	913325.N799_04570	4.433e-42	164.0	COG5400@1|root,COG5400@2|Bacteria,1NDMP@1224|Proteobacteria,1SFZS@1236|Gammaproteobacteria,1XD1Z@135614|Xanthomonadales	135614|Xanthomonadales	S	conserved protein UCP033924	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3235893_8	861299.J421_6213	2.977e-26	110.0	COG5470@1|root,COG5470@2|Bacteria,1ZU5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158456_k127_3235893_7	1288298.rosmuc_00727	5.457e-30	127.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2U70U@28211|Alphaproteobacteria,46R21@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
SRR25158456_k127_3235893_4	1499680.CCFE01000011_gene770	3.308e-49	188.0	COG0702@1|root,COG0702@2|Bacteria,1V112@1239|Firmicutes,4HEVN@91061|Bacilli,1ZG8I@1386|Bacillus	91061|Bacilli	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,HIM1,NAD_binding_10
SRR25158456_k127_3235893_9	211114.JOEF01000019_gene511	7.27e-07	61.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E0CM@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
SRR25158456_k127_3240589_1	861299.J421_1512	6.893e-122	404.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	cmr	-	2.7.4.9	ko:K00943,ko:K08217,ko:K18833	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	br01600,ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.2,2.A.1.21.22	-	-	MFS_1,MFS_3
SRR25158456_k127_3240589_4	398525.KB900701_gene4203	2.107e-10	69.0	COG1309@1|root,COG1309@2|Bacteria,1N2QP@1224|Proteobacteria,2UD2J@28211|Alphaproteobacteria,3JY0J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
SRR25158456_k127_3240589_0	1163407.UU7_04752	2.649e-240	773.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,1RPC7@1236|Gammaproteobacteria,1X51W@135614|Xanthomonadales	135614|Xanthomonadales	M	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158456_k127_3240589_5	693746.OBV_21700	1.395e-07	55.0	2EHZK@1|root,33BR3@2|Bacteria,1VKWR@1239|Firmicutes,24U7R@186801|Clostridia,2N7X2@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3240589_3	1242864.D187_007053	6.839e-18	100.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158456_k127_3240589_2	760117.JN27_11195	2.555e-39	164.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Chlorophyllase2,DLH,Hydrolase_4,Peptidase_S9
SRR25158456_k127_324407_0	1120999.JONM01000033_gene447	0.0	1535.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KQ86@206351|Neisseriales	206351|Neisseriales	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_3247762_5	221288.JH992901_gene4556	5.75e-15	88.0	COG1404@1|root,COG1404@2|Bacteria,1G67C@1117|Cyanobacteria,1JHCV@1189|Stigonemataceae	1117|Cyanobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158456_k127_3247762_2	710686.Mycsm_04950	5.505e-251	822.0	COG0419@1|root,COG0419@2|Bacteria,2I9QM@201174|Actinobacteria,23CMM@1762|Mycobacteriaceae	201174|Actinobacteria	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
SRR25158456_k127_3247762_1	102129.Lepto7375DRAFT_3751	2.623e-274	911.0	COG0222@1|root,COG0222@2|Bacteria,1GBZT@1117|Cyanobacteria,1HEC7@1150|Oscillatoriales	1117|Cyanobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3247762_0	272134.KB731324_gene1542	0.0	1071.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF4349,Flg_new,HWE_HK,Methyltransf_21,PAS_10,SBP_bac_5
SRR25158456_k127_3247762_3	357808.RoseRS_3139	3.647e-146	486.0	28H5N@1|root,2Z7I8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3247762_4	404589.Anae109_3272	5.194e-66	255.0	COG3012@1|root,COG3012@2|Bacteria,1NV40@1224|Proteobacteria	1224|Proteobacteria	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384,SEC-C
SRR25158456_k127_3249631_3	1169144.KB910924_gene629	1.71e-67	244.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacF	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158456_k127_3249631_4	309799.DICTH_1311	4.826e-60	213.0	COG0299@1|root,COG0299@2|Bacteria	2|Bacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2,6.3.2.6,6.3.4.13	ko:K11175,ko:K13713	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04144,R04325,R04326,R04591	RC00026,RC00064,RC00090,RC00162,RC00166,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
SRR25158456_k127_3249631_2	936589.HMPREF1521_1195	2.458e-115	382.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4H3CU@909932|Negativicutes	909932|Negativicutes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158456_k127_3249631_0	1122137.AQXF01000003_gene2417	1.81e-160	527.0	COG2234@1|root,COG2234@2|Bacteria,1NVWC@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158456_k127_3249631_1	1121920.AUAU01000018_gene1806	4.61e-148	477.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180,2.3.1.262	ko:K00648,ko:K18003	ko00061,ko00405,ko01100,ko01130,ko01212,ko02024,ko02025,map00061,map00405,map01100,map01130,map01212,map02024,map02025	M00082,M00083	R10707,R11586,R11587,R11588	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158456_k127_3249631_5	926560.KE387023_gene2169	5.584e-13	70.0	COG1281@1|root,COG1281@2|Bacteria,1WJ1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
SRR25158456_k127_3251971_5	28229.ND2E_1950	1.529e-12	78.0	COG0308@1|root,COG0823@1|root,COG0308@2|Bacteria,COG0823@2|Bacteria,1R8QH@1224|Proteobacteria,1RN7D@1236|Gammaproteobacteria,2Q7PR@267889|Colwelliaceae	1236|Gammaproteobacteria	EU	COG0823 Periplasmic component of the Tol biopolymer transport system	VVA0929	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158456_k127_3251971_1	998674.ATTE01000001_gene987	1.625e-39	161.0	2DBAY@1|root,2Z84S@2|Bacteria,1R7V4@1224|Proteobacteria,1S1T1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
SRR25158456_k127_3251971_6	99158.XP_008887721.1	0.0005698	52.0	KOG4840@1|root,KOG4840@2759|Eukaryota,3YGEJ@5794|Apicomplexa,3YM07@5796|Coccidia,3YTMI@5809|Sarcocystidae	5794|Apicomplexa	S	Protein of unknown function (DUF1749)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1749
SRR25158456_k127_3251971_0	493475.GARC_4807	1.183e-45	170.0	COG4319@1|root,COG4319@2|Bacteria,1N1VU@1224|Proteobacteria,1S9IS@1236|Gammaproteobacteria,46BCT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158456_k127_3251971_3	204669.Acid345_1193	4.671e-28	123.0	COG1381@1|root,COG1381@2|Bacteria,3Y4AX@57723|Acidobacteria,2JJ0T@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158456_k127_3251971_2	1487953.JMKF01000057_gene4400	1.067e-35	145.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H8P0@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158456_k127_3251971_4	13333.ERN16858	8.464e-26	123.0	COG0169@1|root,KOG0692@2759|Eukaryota,37I1M@33090|Viridiplantae,3GDN1@35493|Streptophyta	35493|Streptophyta	E	Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase	-	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
SRR25158456_k127_3271320_6	1392491.JIAE01000001_gene1597	6.612e-17	86.0	COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,25F3V@186801|Clostridia,3WP88@541000|Ruminococcaceae	186801|Clostridia	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3271320_3	1449353.JQMQ01000005_gene2744	2.36e-111	371.0	COG4260@1|root,COG4260@2|Bacteria,2HUEV@201174|Actinobacteria,2NKEP@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
SRR25158456_k127_3271320_4	204669.Acid345_0106	9.678e-32	130.0	COG1586@1|root,COG1586@2|Bacteria,3Y8GM@57723|Acidobacteria	57723|Acidobacteria	E	S-adenosylmethionine decarboxylase	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
SRR25158456_k127_3271320_1	1121920.AUAU01000009_gene1851	1.358e-150	502.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SRR25158456_k127_3271320_7	1192034.CAP_1496	1.421e-11	71.0	2DI1Z@1|root,301RV@2|Bacteria,1NM7Q@1224|Proteobacteria,433HJ@68525|delta/epsilon subdivisions,2WXZG@28221|Deltaproteobacteria,2Z1QD@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SRR25158456_k127_3271320_0	903818.KI912268_gene728	6.874e-188	599.0	COG4262@1|root,COG4262@2|Bacteria,3Y3M2@57723|Acidobacteria	57723|Acidobacteria	S	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158456_k127_3271320_2	1121920.AUAU01000009_gene1855	2.464e-143	484.0	COG1232@1|root,COG1232@2|Bacteria,3Y3KX@57723|Acidobacteria	57723|Acidobacteria	H	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158456_k127_3271320_10	1126627.BAWE01000004_gene3148	2.803e-07	58.0	COG5611@1|root,COG5611@2|Bacteria,1RDUI@1224|Proteobacteria,2U8YA@28211|Alphaproteobacteria,3K09M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_3271320_11	870187.Thini_3745	5.66e-07	54.0	COG2002@1|root,COG2002@2|Bacteria,1NBKK@1224|Proteobacteria	1224|Proteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	PrlF_antitoxin
SRR25158456_k127_3271320_8	215803.DB30_5923	3.405e-09	70.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158456_k127_3271320_5	452637.Oter_2862	4.144e-26	124.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2862|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3271320_12	134676.ACPL_5709	7.908e-07	60.0	COG5479@1|root,COG5479@2|Bacteria	2|Bacteria	M	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP
SRR25158456_k127_3271320_9	1297742.A176_04443	4.475e-08	55.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158456_k127_3272859_1	1047013.AQSP01000114_gene700	2.244e-38	151.0	COG3093@1|root,COG3093@2|Bacteria,2NR60@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
SRR25158456_k127_3272859_2	1407650.BAUB01000023_gene2664	5.428e-35	135.0	COG3549@1|root,COG3549@2|Bacteria,1GPIN@1117|Cyanobacteria,1H3BR@1129|Synechococcus	1117|Cyanobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
SRR25158456_k127_3272859_4	1449126.JQKL01000008_gene255	2.136e-27	129.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,26AR3@186813|unclassified Clostridiales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9
SRR25158456_k127_3272859_8	571.MC52_02340	2.909e-06	51.0	COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,1S8S8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	protein conserved in bacteria	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
SRR25158456_k127_3272859_0	404589.Anae109_3817	2.129e-67	240.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	pph1	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SRR25158456_k127_3272859_6	932678.THERU_07735	1.085e-11	77.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158456_k127_3272859_3	378806.STAUR_4598	2.702e-32	140.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3272859_5	1047013.AQSP01000072_gene985	1.488e-22	109.0	COG1426@1|root,COG1426@2|Bacteria,2NQ7E@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
SRR25158456_k127_3276114_1	941449.dsx2_1126	5.026e-36	158.0	COG1216@1|root,COG1216@2|Bacteria,1QYVR@1224|Proteobacteria,43CT8@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
SRR25158456_k127_3276114_0	1303518.CCALI_01669	4.979e-103	352.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3276114_3	794903.OPIT5_12300	2.271e-09	70.0	COG5434@1|root,COG5434@2|Bacteria,46Y23@74201|Verrucomicrobia,3K8TF@414999|Opitutae	414999|Opitutae	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
SRR25158456_k127_3276114_2	197221.22293957	2.207e-09	68.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria	1117|Cyanobacteria	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_3290363_5	6500.XP_005098014.1	2.898e-05	57.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_3,Ank_4,NACHT
SRR25158456_k127_3290363_1	706587.Desti_3511	1.336e-39	164.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158456_k127_3290363_0	1192034.CAP_0875	7.261e-91	314.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158456_k127_3290363_4	316274.Haur_1305	1.219e-23	115.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158456_k127_3290363_2	99598.Cal7507_1941	2.217e-32	128.0	COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria,1HPP8@1161|Nostocales	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
SRR25158456_k127_3290363_3	32057.KB217478_gene1995	2.42e-25	109.0	COG2929@1|root,COG2929@2|Bacteria,1G8FA@1117|Cyanobacteria	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
SRR25158456_k127_3293222_0	639282.DEFDS_0235	0.0	1035.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GF76@200930|Deferribacteres	200930|Deferribacteres	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158456_k127_3293222_3	546414.Deide_04240	0.0004224	52.0	2DVTT@1|root,33X4Y@2|Bacteria,1WKIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
SRR25158456_k127_3293222_1	1470593.BW43_00386	8.466e-36	142.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,1S99C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158456_k127_3293222_2	1195236.CTER_2811	1.013e-18	94.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3WGDE@541000|Ruminococcaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158456_k127_3294765_1	102125.Xen7305DRAFT_00018990	1.389e-41	166.0	COG2850@1|root,COG2850@2|Bacteria,1G20K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Cupin superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158456_k127_3294765_0	1340493.JNIF01000003_gene3961	1.939e-88	309.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_3300369_6	251221.35214310	1.822e-08	63.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158456_k127_3300369_3	1157708.KB907457_gene2563	8.756e-35	144.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2VRWE@28216|Betaproteobacteria,4AEHP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158456_k127_3300369_0	1246995.AFR_12120	1.857e-71	276.0	COG0457@1|root,COG0457@2|Bacteria	1246995.AFR_12120|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3300369_4	1379270.AUXF01000002_gene1782	5.971e-31	135.0	28UH1@1|root,2ZGMU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SRR25158456_k127_3300369_5	1499967.BAYZ01000105_gene3476	3.711e-21	98.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158456_k127_3300369_2	83406.HDN1F_27190	1.927e-41	174.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,1MWPN@1224|Proteobacteria,1T1IF@1236|Gammaproteobacteria,1J794@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3,PAS,PAS_4,PAS_9
SRR25158456_k127_3300369_1	56780.SYN_01953	8.768e-58	208.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_3304070_2	279010.BL03314	2.728e-68	235.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_3304070_0	867903.ThesuDRAFT_01903	3.789e-103	349.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia	186801|Clostridia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
SRR25158456_k127_3304070_3	234267.Acid_5358	9.703e-47	172.0	COG2318@1|root,COG2318@2|Bacteria,3Y5DP@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_3304070_5	760568.Desku_3410	1.421e-10	70.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_3304070_4	861299.J421_2181	1.743e-26	128.0	COG4995@1|root,COG4995@2|Bacteria,1ZUKA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_3304070_1	861299.J421_5806	4.355e-94	341.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GUN4,GUN4_N,Peptidase_C13,Peptidase_C14,TPR_10
SRR25158456_k127_3305422_5	1173028.ANKO01000112_gene4824	1.919e-24	109.0	2DMJE@1|root,32RYR@2|Bacteria,1G6SI@1117|Cyanobacteria,1HBXF@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SRR25158456_k127_3305422_6	675806.VII_001135	2.378e-18	99.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1XUTA@135623|Vibrionales	135623|Vibrionales	S	membrane	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158456_k127_3305422_3	448385.sce8988	1.719e-25	117.0	COG0671@1|root,COG0671@2|Bacteria,1N5FU@1224|Proteobacteria,43ADS@68525|delta/epsilon subdivisions,2WQ8X@28221|Deltaproteobacteria,2Z39W@29|Myxococcales	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158456_k127_3305422_2	196490.AUEZ01000036_gene6081	5.707e-33	138.0	COG3828@1|root,COG3828@2|Bacteria,1R5XA@1224|Proteobacteria,2U51F@28211|Alphaproteobacteria,3K5VQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	GSDH,ThuA
SRR25158456_k127_3305422_1	1192034.CAP_3960	2.432e-42	173.0	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,43ACX@68525|delta/epsilon subdivisions,2X5SX@28221|Deltaproteobacteria	1224|Proteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_3305422_4	215803.DB30_7168	8.008e-25	121.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158456_k127_3305422_0	671143.DAMO_3054	3.434e-106	357.0	COG5621@1|root,COG5621@2|Bacteria,2NPFN@2323|unclassified Bacteria	2|Bacteria	S	Lipocalin-like domain	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158456_k127_3306227_3	234267.Acid_2379	7.298e-67	259.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158456_k127_3306227_1	929556.Solca_1317	4.378e-94	314.0	COG4912@1|root,COG4912@2|Bacteria,4NKAY@976|Bacteroidetes,1J15C@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158456_k127_3306227_0	509635.N824_26440	1.013e-149	478.0	COG2267@1|root,COG2267@2|Bacteria,4PN25@976|Bacteroidetes	976|Bacteroidetes	I	PFAM Alpha Beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158456_k127_3306227_7	234267.Acid_3133	3.818e-08	65.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y7SH@57723|Acidobacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,PD40,TPR_10,TPR_12,TPR_8
SRR25158456_k127_3306227_2	365046.Rta_14315	2.768e-83	294.0	COG2110@1|root,COG2110@2|Bacteria,1RH4K@1224|Proteobacteria,2VXXT@28216|Betaproteobacteria,4AIWB@80864|Comamonadaceae	28216|Betaproteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3306227_4	1280948.HY36_15940	8.843e-41	157.0	COG2189@1|root,COG2189@2|Bacteria,1QVE3@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3308526_0	1052684.PPM_3217	0.0	3684.0	COG2227@1|root,COG3321@1|root,COG4221@1|root,COG2227@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1VU8Z@1239|Firmicutes,4HFCI@91061|Bacilli,2771J@186822|Paenibacillaceae	91061|Bacilli	Q	Polyketide synthase modules and related proteins	pksR	-	-	ko:K13613,ko:K13614	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_3308526_2	588581.Cpap_3716	3.177e-186	662.0	COG3321@1|root,COG3321@2|Bacteria,1VU8Z@1239|Firmicutes,24YJI@186801|Clostridia	186801|Clostridia	Q	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_3308526_1	391587.KAOT1_04255	0.0	3208.0	COG3321@1|root,COG3321@2|Bacteria,4PKD5@976|Bacteroidetes,1HYG4@117743|Flavobacteriia	976|Bacteroidetes	Q	COG3321 Polyketide synthase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase,DUF2156,ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_3308526_3	1380391.JIAS01000011_gene5171	1.05e-07	64.0	COG1834@1|root,COG1834@2|Bacteria,1R7NG@1224|Proteobacteria,2U4ZK@28211|Alphaproteobacteria,2JXVS@204441|Rhodospirillales	204441|Rhodospirillales	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158456_k127_3323530_3	639282.DEFDS_2156	2.28e-69	240.0	COG1220@1|root,COG1220@2|Bacteria,2GF0V@200930|Deferribacteres	200930|Deferribacteres	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158456_k127_3323530_4	1382359.JIAL01000001_gene1358	5.17e-69	245.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria,2JIR7@204432|Acidobacteriia	204432|Acidobacteriia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
SRR25158456_k127_3323530_5	338966.Ppro_0565	1.483e-31	134.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,42PJJ@68525|delta/epsilon subdivisions,2WTZ5@28221|Deltaproteobacteria,43T0Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
SRR25158456_k127_3323530_7	1224746.B932_1381	2.805e-10	68.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
SRR25158456_k127_3323530_1	1382359.JIAL01000001_gene841	5.707e-153	490.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158456_k127_3323530_0	1242864.D187_001443	6.012e-265	850.0	COG0421@1|root,COG0457@1|root,COG0421@2|Bacteria,COG0457@2|Bacteria,1QXA2@1224|Proteobacteria,43C3D@68525|delta/epsilon subdivisions,2WUH2@28221|Deltaproteobacteria,2YYH4@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158456_k127_3323530_6	1232410.KI421416_gene2621	1.605e-27	132.0	2EF9T@1|root,3392P@2|Bacteria,1P8J3@1224|Proteobacteria,4324V@68525|delta/epsilon subdivisions,2WYC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3323530_2	1085623.GNIT_3572	4.24e-70	269.0	COG1404@1|root,COG5183@1|root,COG1404@2|Bacteria,COG5183@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,46BFY@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8,SLH
SRR25158456_k127_3332379_0	243231.GSU1644	2.894e-273	851.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,43RZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158456_k127_3332379_3	1122604.JONR01000033_gene34	1.141e-49	199.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158456_k127_3332379_6	1121927.GOHSU_14_01420	6.78e-12	77.0	COG3275@1|root,COG3275@2|Bacteria,2GJD4@201174|Actinobacteria,4GBVY@85026|Gordoniaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
SRR25158456_k127_3332379_4	234267.Acid_2196	4.25e-43	172.0	COG2972@1|root,COG2972@2|Bacteria,3Y4IB@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
SRR25158456_k127_3332379_5	269799.Gmet_1472	4.452e-40	171.0	COG0517@1|root,COG2208@1|root,COG0517@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42RQT@68525|delta/epsilon subdivisions,2WW12@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,SpoIIE
SRR25158456_k127_3332379_1	290397.Adeh_3989	3.737e-141	460.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,42RD4@68525|delta/epsilon subdivisions,2WN11@28221|Deltaproteobacteria,2YU83@29|Myxococcales	28221|Deltaproteobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_3332379_2	391625.PPSIR1_35862	9.852e-60	222.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158456_k127_3333129_2	378806.STAUR_0284	3.079e-110	367.0	COG1075@1|root,COG1075@2|Bacteria,1MXXB@1224|Proteobacteria,438M0@68525|delta/epsilon subdivisions,2X3VC@28221|Deltaproteobacteria,2YX83@29|Myxococcales	28221|Deltaproteobacteria	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
SRR25158456_k127_3333129_1	1192034.CAP_3457	6.693e-142	460.0	COG2308@1|root,COG2308@2|Bacteria,1Q3RI@1224|Proteobacteria,439JB@68525|delta/epsilon subdivisions,2X4VX@28221|Deltaproteobacteria,2YZQ5@29|Myxococcales	28221|Deltaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3333129_0	215803.DB30_8464	3.345e-241	781.0	COG0421@1|root,COG0457@1|root,COG0421@2|Bacteria,COG0457@2|Bacteria,1QXA2@1224|Proteobacteria,43C3D@68525|delta/epsilon subdivisions,2WUH2@28221|Deltaproteobacteria,2YYH4@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158456_k127_3333129_4	290397.Adeh_3633	3.157e-94	311.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SRR25158456_k127_3333129_6	903818.KI912268_gene3366	6.369e-65	225.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
SRR25158456_k127_3333129_5	204669.Acid345_1973	6.695e-70	243.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria,2JHQM@204432|Acidobacteriia	204432|Acidobacteriia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158456_k127_3333129_7	1395587.P364_0103380	2.838e-22	113.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26Y4X@186822|Paenibacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158456_k127_3333129_3	443143.GM18_0169	7.042e-101	349.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158456_k127_3333129_8	1192868.CAIU01000040_gene4440	1.001e-11	66.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158456_k127_3333129_9	1027396.LMOSA_6860	1.8e-11	65.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,26IPT@186820|Listeriaceae	91061|Bacilli	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158456_k127_3337173_0	944435.AXAJ01000013_gene2722	1.694e-172	586.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_3337173_4	1397696.KK211189_gene1625	4.208e-14	78.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,3WE3D@539002|Bacillales incertae sedis	91061|Bacilli	KT	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_3337173_3	262724.TT_C0462	1.494e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,1WK6R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158456_k127_3337173_2	553178.CAPGI0001_0607	7.376e-49	198.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1HX6Y@117743|Flavobacteriia,1EQ16@1016|Capnocytophaga	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
SRR25158456_k127_3337173_1	246197.MXAN_6138	1.437e-111	361.0	COG0262@1|root,COG0262@2|Bacteria,1QH1Q@1224|Proteobacteria,4341U@68525|delta/epsilon subdivisions,2X4QE@28221|Deltaproteobacteria,2YZE6@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158456_k127_3341895_2	1443665.JACA01000024_gene3399	5.294e-25	113.0	2ACTN@1|root,312EH@2|Bacteria,4PHCH@976|Bacteroidetes,1II24@117743|Flavobacteriia,2YKJI@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3341895_0	715451.ambt_18785	6.201e-180	580.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,4640X@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158456_k127_3341895_1	221360.RS9917_00557	6.14e-26	112.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_3344893_10	1120972.AUMH01000023_gene544	2.953e-20	96.0	COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,4HGBS@91061|Bacilli	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158456_k127_3344893_8	1220534.B655_0693	5.442e-26	121.0	arCOG03999@1|root,arCOG03999@2157|Archaea,2Y4KU@28890|Euryarchaeota	28890|Euryarchaeota	E	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SRR25158456_k127_3344893_9	63737.Npun_R1943	3.995e-25	123.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
SRR25158456_k127_3344893_14	637390.AFOH01000039_gene2437	2.48e-07	53.0	2EJ6D@1|root,33CXK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3344893_4	1248916.ANFY01000005_gene2781	5.748e-71	244.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2U7G8@28211|Alphaproteobacteria,2K456@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158456_k127_3344893_1	1121920.AUAU01000004_gene849	3.224e-118	392.0	COG0861@1|root,COG0861@2|Bacteria,3Y37C@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158456_k127_3344893_2	1254432.SCE1572_46130	1.454e-102	343.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2YTTQ@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158456_k127_3344893_3	234267.Acid_0207	1.353e-96	325.0	COG0583@1|root,COG0583@2|Bacteria,3Y34A@57723|Acidobacteria	57723|Acidobacteria	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158456_k127_3344893_7	880072.Desac_2694	1.563e-40	165.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MRZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158456_k127_3344893_0	215803.DB30_2967	2.561e-141	456.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,42Y78@68525|delta/epsilon subdivisions,2X3CW@28221|Deltaproteobacteria,2YUS0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
SRR25158456_k127_3344893_5	1501230.ET33_33920	1.686e-52	201.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,26QDE@186822|Paenibacillaceae	91061|Bacilli	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
SRR25158456_k127_3344893_6	871963.Desdi_2340	3.391e-47	188.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
SRR25158456_k127_3344893_15	1167006.UWK_02741	0.0001581	52.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WNBB@28221|Deltaproteobacteria,2MK5J@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158456_k127_3344893_12	1114970.PSF113_2940	1.245e-14	81.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1YNMI@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158456_k127_3344893_11	1352941.M877_10305	1.125e-19	102.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	fbpC	-	-	ko:K02052,ko:K02062	ko02010,ko02024,map02010,map02024	M00191,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.19	-	-	ABC_tran,TOBE_2
SRR25158456_k127_3344893_13	639030.JHVA01000001_gene3439	3.626e-13	76.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria,2JJQD@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
SRR25158456_k127_3355474_11	291985.CCSI01000006_gene1168	1.352e-28	119.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,2U9EX@28211|Alphaproteobacteria,2K64Z@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
SRR25158456_k127_3355474_1	1267533.KB906733_gene3392	1.666e-89	301.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158456_k127_3355474_10	935863.AWZR01000007_gene225	2.769e-29	123.0	COG3422@1|root,COG3422@2|Bacteria,1N0S6@1224|Proteobacteria,1S8R7@1236|Gammaproteobacteria,1X85F@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF1508)	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
SRR25158456_k127_3355474_13	240015.ACP_0644	2.3e-14	85.0	COG5343@1|root,COG5343@2|Bacteria,3Y541@57723|Acidobacteria,2JJTM@204432|Acidobacteriia	204432|Acidobacteriia	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158456_k127_3355474_7	309801.trd_A0611	1.392e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YAV@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_3355474_9	1121372.AULK01000003_gene294	2.374e-35	151.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4FKJB@85023|Microbacteriaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158456_k127_3355474_0	1048834.TC41_1964	8.487e-122	419.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HBS0@91061|Bacilli,279F0@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158456_k127_3355474_6	1165096.ARWF01000001_gene2279	8.43e-38	151.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	DUF2318,FTR1
SRR25158456_k127_3355474_5	247490.KSU1_D0967	8.363e-42	159.0	COG0735@1|root,COG0735@2|Bacteria,2IZJY@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158456_k127_3355474_14	1408424.JHYI01000038_gene2432	5.042e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158456_k127_3355474_3	1142394.PSMK_08700	6.771e-44	183.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1
SRR25158456_k127_3355474_8	903818.KI912269_gene353	9.043e-36	145.0	2ET40@1|root,33KN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3355474_4	1173027.Mic7113_0494	4.261e-43	173.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H8P0@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158456_k127_3355474_12	1121405.dsmv_3809	5.776e-16	90.0	COG0824@1|root,COG0824@2|Bacteria,1MZTU@1224|Proteobacteria,42WZM@68525|delta/epsilon subdivisions,2WT0J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158456_k127_3355474_2	471223.GWCH70_1838	4.161e-86	291.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1WE8S@129337|Geobacillus	91061|Bacilli	E	HMGL-like	yngG	GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158456_k127_3359288_1	204669.Acid345_1474	8.699e-154	500.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158456_k127_3359288_7	502025.Hoch_4605	2.631e-36	156.0	2FCEE@1|root,344HX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
SRR25158456_k127_3359288_8	10228.TriadP56187	1.136e-28	119.0	2CDB0@1|root,2QUGZ@2759|Eukaryota,39UAM@33154|Opisthokonta,3BJ8Z@33208|Metazoa	33208|Metazoa	C	thyroxine 5'-deiodinase activity	DIO1	GO:0003674,GO:0003824,GO:0004800,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008430,GO:0009987,GO:0010817,GO:0016020,GO:0016491,GO:0018958,GO:0042403,GO:0042445,GO:0044237,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901360,GO:1901564,GO:1901615	1.21.99.4	ko:K01562	ko04919,map04919	-	-	-	ko00000,ko00001,ko01000	-	-	-	T4_deiodinase
SRR25158456_k127_3359288_4	1385517.N800_00455	2.652e-42	180.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria	1224|Proteobacteria	MU	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158456_k127_3359288_5	402777.KB235903_gene2096	1.19e-39	171.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
SRR25158456_k127_3359288_2	219305.MCAG_01386	2.788e-121	427.0	COG5276@1|root,COG5276@2|Bacteria,2IAAZ@201174|Actinobacteria,4DBJS@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,P_proprotein
SRR25158456_k127_3359288_0	1124983.PFLCHA0_c20770	1.524e-173	593.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1QU2N@1224|Proteobacteria,1RYA1@1236|Gammaproteobacteria,1YTG4@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	VP1463	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,NAD_binding_8
SRR25158456_k127_3359288_3	1408422.JHYF01000008_gene3769	1.583e-42	181.0	COG0438@1|root,COG0438@2|Bacteria,1TQNE@1239|Firmicutes,24C02@186801|Clostridia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158456_k127_3359288_6	574087.Acear_0280	1.841e-36	157.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,3WAKY@53433|Halanaerobiales	186801|Clostridia	S	TIGRFAM polysaccharide pyruvyl transferase CsaB	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
SRR25158456_k127_3363455_2	861299.J421_6133	8.299e-47	181.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	dcsG	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,RimK
SRR25158456_k127_3363455_3	136993.KB900626_gene3765	3.417e-38	152.0	COG0607@1|root,COG0607@2|Bacteria,1RHUS@1224|Proteobacteria,2U9CN@28211|Alphaproteobacteria,37142@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158456_k127_3363455_0	266117.Rxyl_0136	2.322e-133	442.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4CQ4C@84995|Rubrobacteria	84995|Rubrobacteria	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158456_k127_3363455_1	713586.KB900536_gene377	1.167e-126	420.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,1T1T1@1236|Gammaproteobacteria,1X2QZ@135613|Chromatiales	135613|Chromatiales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158456_k127_3363455_5	220664.PFL_2027	1.627e-28	131.0	COG0500@1|root,COG2226@2|Bacteria,1QXCK@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158456_k127_3363455_7	316067.Geob_0908	2.658e-13	76.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SRR25158456_k127_3363455_6	215803.DB30_8013	1.443e-14	85.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria,2Z0DC@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
SRR25158456_k127_3363455_4	1278073.MYSTI_05492	3.02e-37	145.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2YUII@29|Myxococcales	28221|Deltaproteobacteria	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158456_k127_3365237_3	1163409.UUA_17210	4.248e-47	177.0	arCOG07533@1|root,2ZF5I@2|Bacteria,1RB8D@1224|Proteobacteria,1SBRH@1236|Gammaproteobacteria,1X79G@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158456_k127_3365237_4	1502850.FG91_03868	4.411e-17	89.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,2UCNR@28211|Alphaproteobacteria,2K0VY@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_3365237_0	234267.Acid_7636	6.016e-192	628.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y333@57723|Acidobacteria	57723|Acidobacteria	KLTU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
SRR25158456_k127_3365237_1	483219.LILAB_18670	2.696e-76	270.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_2,Glyco_transf_4,Glyco_transf_9,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_3365237_2	561175.KB894093_gene2779	1.257e-61	235.0	2DBSB@1|root,2ZARC@2|Bacteria	2|Bacteria	S	MAC/Perforin domain	-	-	-	-	-	-	-	-	-	-	-	-	MACPF
SRR25158456_k127_3375598_0	290397.Adeh_3188	3.74e-127	427.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955	-	-	-	-	ko00000	-	-	-	Big_4,FTP,Laminin_G_3,PA,Peptidase_M36
SRR25158456_k127_3375598_1	509191.AEDB02000073_gene2010	1.834e-87	302.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	VPA0780	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
SRR25158456_k127_3379426_25	364733.XP_007786655.1	2.367e-10	72.0	COG0639@1|root,KOG0371@2759|Eukaryota,391PG@33154|Opisthokonta,3NW7J@4751|Fungi,3QSRT@4890|Ascomycota,20AWW@147545|Eurotiomycetes,3MRX4@451870|Chaetothyriomycetidae	4751|Fungi	T	Calcineurin-like phosphoesterase	-	GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031090,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0098588,GO:0098805,GO:0098852	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRR25158456_k127_3379426_17	1333856.L686_04560	4.755e-39	156.0	COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,1S7KA@1236|Gammaproteobacteria,1Z0XH@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158456_k127_3379426_2	1303518.CCALI_00492	4.186e-164	540.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158456_k127_3379426_1	448385.sce0836	9.44e-185	601.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158456_k127_3379426_5	1128421.JAGA01000002_gene791	1.328e-117	396.0	COG0477@1|root,COG0477@2|Bacteria,2NQG6@2323|unclassified Bacteria	2|Bacteria	EGP	Sugar (and other) transporter	bmr3_1	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_3379426_15	404589.Anae109_3633	1.733e-50	200.0	COG1215@1|root,COG1215@2|Bacteria,1Q6U2@1224|Proteobacteria,430X8@68525|delta/epsilon subdivisions,2WMWY@28221|Deltaproteobacteria,2Z0V6@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	ugcG	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
SRR25158456_k127_3379426_13	289376.THEYE_A1784	2.729e-63	227.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	MGDG_synth,PHP
SRR25158456_k127_3379426_9	215803.DB30_5900	7.908e-103	351.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria,2YYJS@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 1	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158456_k127_3379426_22	1123270.ATUR01000010_gene1903	8.586e-21	106.0	2EA9M@1|root,334E1@2|Bacteria,1ND0N@1224|Proteobacteria,2UIJ1@28211|Alphaproteobacteria,2K8CC@204457|Sphingomonadales	204457|Sphingomonadales	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158456_k127_3379426_12	1356852.N008_10575	3.433e-70	273.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,47MBP@768503|Cytophagia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158456_k127_3379426_4	472759.Nhal_3833	1.798e-122	427.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1MX4K@1224|Proteobacteria,1RP6B@1236|Gammaproteobacteria,1X0CV@135613|Chromatiales	135613|Chromatiales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_3379426_24	273121.WS1817	1.257e-11	74.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,42MG4@68525|delta/epsilon subdivisions,2YME4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	response regulator	ompR	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_3379426_16	419947.MRA_1849	3.728e-42	158.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158456_k127_3379426_23	419947.MRA_1850	1.398e-17	86.0	2BE1Z@1|root,327SM@2|Bacteria,2HDGJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3379426_3	471853.Bcav_2715	7.832e-161	522.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_3379426_14	234267.Acid_7414	1.024e-52	202.0	COG4412@1|root,COG4934@1|root,COG4412@2|Bacteria,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	FTP,He_PIG,PLDc_2,Peptidase_M4,Peptidase_M4_C,Peptidase_M6
SRR25158456_k127_3379426_11	204669.Acid345_1110	4.848e-73	253.0	COG3217@1|root,COG3217@2|Bacteria,3Y5TQ@57723|Acidobacteria,2JNG0@204432|Acidobacteriia	204432|Acidobacteriia	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158456_k127_3379426_0	316274.Haur_4431	3.459e-185	598.0	COG3211@1|root,COG3211@2|Bacteria,2G7MB@200795|Chloroflexi,37676@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158456_k127_3379426_26	1122201.AUAZ01000016_gene73	6.33e-07	58.0	2CDP6@1|root,32RY5@2|Bacteria,1N1TI@1224|Proteobacteria,1SC2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3379426_7	886293.Sinac_0383	6.205e-115	385.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158456_k127_3379426_8	450851.PHZ_c1174	8.665e-107	357.0	COG2270@1|root,COG2270@2|Bacteria,1R0EG@1224|Proteobacteria,2U3Z4@28211|Alphaproteobacteria,2KFT5@204458|Caulobacterales	204458|Caulobacterales	S	Major Facilitator Superfamily	-	-	-	ko:K18833	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.2	-	-	MFS_1
SRR25158456_k127_3379426_19	401053.AciPR4_2475	1.043e-31	143.0	2B1QU@1|root,31U6H@2|Bacteria,3Y5EE@57723|Acidobacteria,2JJUF@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
SRR25158456_k127_3379426_6	84531.JMTZ01000065_gene1873	9.721e-116	380.0	COG0491@1|root,COG0491@2|Bacteria,1MUAV@1224|Proteobacteria,1RNVB@1236|Gammaproteobacteria,1X9YD@135614|Xanthomonadales	135614|Xanthomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3379426_18	159087.Daro_1795	1.477e-33	138.0	29AFQ@1|root,2ZXFW@2|Bacteria,1RGFB@1224|Proteobacteria,2VQD0@28216|Betaproteobacteria,2KYP8@206389|Rhodocyclales	206389|Rhodocyclales	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
SRR25158456_k127_3379426_10	290397.Adeh_4006	6.827e-74	270.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158456_k127_3379426_20	215803.DB30_0087	1.964e-30	134.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158456_k127_3380488_0	1254432.SCE1572_45305	4.565e-81	286.0	COG1233@1|root,COG1233@2|Bacteria,1QXT4@1224|Proteobacteria,43C5J@68525|delta/epsilon subdivisions,2X7FU@28221|Deltaproteobacteria,2YUIG@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158456_k127_3380488_1	710686.Mycsm_05706	2.174e-71	260.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,23FDA@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158456_k127_3381052_1	29581.BW37_04035	3.112e-30	133.0	2DPW6@1|root,333NE@2|Bacteria,1NM0S@1224|Proteobacteria,2W3RD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3381052_0	29581.BW37_04034	1.397e-78	281.0	COG3220@1|root,COG3220@2|Bacteria,1RH40@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
SRR25158456_k127_3381052_2	1535422.ND16A_2150	4.107e-25	124.0	COG3485@1|root,COG4932@1|root,COG5276@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,CarboxypepD_reg,DUF11,FG-GAP
SRR25158456_k127_3382200_2	1449049.JONW01000007_gene3851	9.937e-46	177.0	2C7KN@1|root,336M6@2|Bacteria,1N4WC@1224|Proteobacteria,2UF5V@28211|Alphaproteobacteria,2KIU5@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3382200_1	204669.Acid345_2395	2.517e-89	323.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
SRR25158456_k127_3382200_0	861299.J421_5946	3.577e-237	772.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
SRR25158456_k127_3383600_2	357808.RoseRS_4060	3.926e-24	119.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_3383600_3	357808.RoseRS_4060	3.078e-20	106.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_3383600_1	1052684.PPM_3220	1.013e-96	323.0	COG1024@1|root,COG1024@2|Bacteria,1TRGW@1239|Firmicutes,4HBJK@91061|Bacilli,26SDQ@186822|Paenibacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	pksH	-	-	ko:K15312	-	-	-	-	ko00000,ko01008	-	-	-	ECH_1
SRR25158456_k127_3383600_0	555079.Toce_1670	0.0	1194.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158456_k127_338375_2	1042163.BRLA_c012100	6.201e-87	312.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,26RZT@186822|Paenibacillaceae	91061|Bacilli	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
SRR25158456_k127_338375_0	404589.Anae109_0101	5.853e-154	499.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2YU1M@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
SRR25158456_k127_338375_6	1110502.TMO_2121	8.204e-55	205.0	COG0484@1|root,COG2214@1|root,COG0484@2|Bacteria,COG2214@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2JQKE@204441|Rhodospirillales	204441|Rhodospirillales	O	Molecular chaperone	cbpA	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
SRR25158456_k127_338375_8	1206741.BAFX01000044_gene3147	7.649e-08	60.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4G0QP@85025|Nocardiaceae	201174|Actinobacteria	S	Appr-1'-p processing enzyme	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158456_k127_338375_7	1499967.BAYZ01000186_gene3960	1.747e-21	107.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
SRR25158456_k127_338375_5	234267.Acid_1840	1.018e-76	264.0	COG1235@1|root,COG1235@2|Bacteria,3Y40S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
SRR25158456_k127_338375_3	1382356.JQMP01000004_gene301	1.3e-85	308.0	COG0128@1|root,COG0128@2|Bacteria,2G6S6@200795|Chloroflexi,27Y0N@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158456_k127_338375_1	768710.DesyoDRAFT_1372	1.29e-113	382.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158456_k127_338375_4	383372.Rcas_3662	3.21e-77	265.0	COG1611@1|root,COG1611@2|Bacteria,2G6IB@200795|Chloroflexi,376GG@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158456_k127_3405152_0	266117.Rxyl_2540	6.592e-208	666.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158456_k127_3411825_0	448385.sce3182	5.394e-174	559.0	COG0304@1|root,COG0304@2|Bacteria,1RB5A@1224|Proteobacteria,42ZA4@68525|delta/epsilon subdivisions,2WTRH@28221|Deltaproteobacteria,2YXYF@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	ko:K00646	-	-	-	-	ko00000,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_3411825_1	1535422.ND16A_2589	7.616e-60	231.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,1RPKB@1236|Gammaproteobacteria,2Q618@267889|Colwelliaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_3415854_4	1173024.KI912149_gene5149	6.307e-54	198.0	COG0500@1|root,COG2226@2|Bacteria,1G24H@1117|Cyanobacteria,1JHP9@1189|Stigonemataceae	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158456_k127_3415854_8	1210884.HG799463_gene9859	4.811e-14	79.0	arCOG13559@1|root,33239@2|Bacteria,2J0W1@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
SRR25158456_k127_3415854_1	1123073.KB899241_gene2060	5.406e-143	466.0	COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria,1RMKT@1236|Gammaproteobacteria,1X3Z6@135614|Xanthomonadales	135614|Xanthomonadales	E	Splits dipeptides with a prolyl residue in the C- terminal position	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158456_k127_3415854_2	208439.AJAP_41645	9.836e-121	407.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_3415854_7	234267.Acid_2429	4.461e-24	105.0	COG3795@1|root,COG3795@2|Bacteria,3Y5P2@57723|Acidobacteria	57723|Acidobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158456_k127_3415854_3	861299.J421_3672	1.477e-100	347.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3415854_5	937777.Deipe_1300	1.993e-44	165.0	COG4639@1|root,COG4639@2|Bacteria	2|Bacteria	Q	AAA domain	Pnkp	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158456_k127_3415854_0	1242864.D187_000143	7.066e-163	531.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42NN9@68525|delta/epsilon subdivisions,2WM5V@28221|Deltaproteobacteria,2Z32B@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase Ligase (LigD)	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158456_k127_3415854_6	944481.JAFP01000001_gene373	2.139e-33	138.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2M75M@213113|Desulfurellales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158456_k127_3432900_0	469383.Cwoe_5055	3.662e-190	655.0	COG1388@1|root,COG1388@2|Bacteria,2IF1H@201174|Actinobacteria	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158456_k127_3432900_3	469383.Cwoe_5056	9.535e-41	165.0	COG2333@1|root,COG2333@2|Bacteria,2GZ7E@201174|Actinobacteria	201174|Actinobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3432900_4	469383.Cwoe_5056	3.256e-40	165.0	COG2333@1|root,COG2333@2|Bacteria,2GZ7E@201174|Actinobacteria	201174|Actinobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3432900_1	1297742.A176_04209	1.98e-187	626.0	2CAPJ@1|root,2Z90A@2|Bacteria,1P1EA@1224|Proteobacteria,4389Z@68525|delta/epsilon subdivisions,2X3JE@28221|Deltaproteobacteria,2YWBF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3432900_2	1297742.A176_04210	3.919e-54	218.0	2DTWK@1|root,33MZR@2|Bacteria,1NPJZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3432900_5	397291.C804_00723	0.0001191	56.0	COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,27J22@186928|unclassified Lachnospiraceae	186801|Clostridia	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,fn3
SRR25158456_k127_3435915_2	1268622.AVS7_04161	1.54e-54	203.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria	1224|Proteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SRR25158456_k127_3435915_1	1317122.ATO12_18150	2.768e-104	356.0	COG0457@1|root,COG0457@2|Bacteria,4NI5H@976|Bacteroidetes,1I5EH@117743|Flavobacteriia,2YHT2@290174|Aquimarina	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
SRR25158456_k127_3435915_3	935567.JAES01000008_gene1982	2.513e-19	98.0	COG3637@1|root,COG3637@2|Bacteria,1RJ11@1224|Proteobacteria,1SXRG@1236|Gammaproteobacteria,1X6MR@135614|Xanthomonadales	135614|Xanthomonadales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3435915_0	1429916.X566_05380	2.027e-263	821.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TT2P@28211|Alphaproteobacteria,3JWSW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158456_k127_344849_1	349521.HCH_01091	1.784e-144	470.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria,1XHPE@135619|Oceanospirillales	135619|Oceanospirillales	F	Guanine deaminase	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158456_k127_344849_4	861299.J421_4207	3.552e-130	450.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_344849_10	867903.ThesuDRAFT_00376	1.099e-43	171.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
SRR25158456_k127_344849_13	316067.Geob_2709	8.747e-09	64.0	2AP2K@1|root,31E40@2|Bacteria,1Q1F7@1224|Proteobacteria,432Y4@68525|delta/epsilon subdivisions,2WX7Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_344849_3	439235.Dalk_0818	2.014e-135	437.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MJ7T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158456_k127_344849_2	1128421.JAGA01000002_gene991	1.211e-136	454.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158456_k127_344849_12	259536.Psyc_1775	6.878e-18	85.0	COG1983@1|root,COG1983@2|Bacteria,1NAUA@1224|Proteobacteria,1SD7E@1236|Gammaproteobacteria,3NPCM@468|Moraxellaceae	1236|Gammaproteobacteria	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
SRR25158456_k127_344849_14	1382356.JQMP01000004_gene664	4.087e-06	59.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,27XMW@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_344849_8	96561.Dole_2588	6.594e-72	259.0	COG1807@1|root,COG1807@2|Bacteria,1RK4G@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_344849_7	383372.Rcas_2039	1.613e-101	342.0	COG2021@1|root,COG2021@2|Bacteria,2G5JD@200795|Chloroflexi,374TP@32061|Chloroflexia	32061|Chloroflexia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158456_k127_344849_6	1380394.JADL01000003_gene4837	1.631e-116	392.0	COG1816@1|root,COG1816@2|Bacteria,1R6Q8@1224|Proteobacteria,2U0BN@28211|Alphaproteobacteria,2JQP7@204441|Rhodospirillales	204441|Rhodospirillales	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158456_k127_344849_5	543632.JOJL01000014_gene9230	4.282e-125	424.0	2EX9M@1|root,33QKC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_344849_0	204669.Acid345_3340	4.713e-253	807.0	COG0550@1|root,COG0550@2|Bacteria,3Y343@57723|Acidobacteria,2JHPW@204432|Acidobacteriia	204432|Acidobacteriia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158456_k127_344849_11	1121272.KB903250_gene2799	2.991e-19	102.0	2EEXH@1|root,338QV@2|Bacteria,2ICQN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
SRR25158456_k127_344849_9	626887.J057_21920	9.161e-65	228.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRR1@1236|Gammaproteobacteria,4646F@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_3457068_7	477184.KYC_20254	1.694e-39	154.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,3T3AA@506|Alcaligenaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRR25158456_k127_3457068_4	441620.Mpop_3532	1.315e-90	312.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2U0DX@28211|Alphaproteobacteria,1JU37@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_3457068_2	1499967.BAYZ01000017_gene6221	3.241e-112	383.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
SRR25158456_k127_3457068_9	1107311.Q767_15005	2.156e-30	126.0	COG3485@1|root,COG3485@2|Bacteria,4NEZ1@976|Bacteroidetes,1I01Q@117743|Flavobacteriia,2NVGG@237|Flavobacterium	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158456_k127_3457068_1	396588.Tgr7_2421	1.622e-159	513.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1WWJU@135613|Chromatiales	135613|Chromatiales	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158456_k127_3457068_8	935848.JAEN01000005_gene3652	1.426e-35	156.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TQSZ@28211|Alphaproteobacteria,2PV2M@265|Paracoccus	28211|Alphaproteobacteria	E	Arginase family	-	-	3.5.3.11,3.5.3.17	ko:K01480,ko:K18459	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158456_k127_3457068_0	1122176.KB903542_gene336	1.182e-170	552.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
SRR25158456_k127_3457068_6	1499967.BAYZ01000180_gene4407	1.296e-41	165.0	COG2177@1|root,COG2177@2|Bacteria,2NPIM@2323|unclassified Bacteria	2|Bacteria	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158456_k127_3457068_5	1121920.AUAU01000005_gene1090	2.198e-78	269.0	COG2884@1|root,COG2884@2|Bacteria	2|Bacteria	D	Cell division ATP-binding protein ftsE	ftsE	GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158456_k127_3457068_11	382464.ABSI01000012_gene2139	3.568e-29	129.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,VPEP
SRR25158456_k127_3457068_10	404589.Anae109_3600	7.447e-30	123.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2YW4G@29|Myxococcales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158456_k127_3457068_3	886293.Sinac_7218	5.619e-91	310.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158456_k127_3460247_0	314285.KT71_17271	2.769e-124	417.0	COG1404@1|root,COG1404@2|Bacteria,1PE2Y@1224|Proteobacteria,1SQ8B@1236|Gammaproteobacteria,1JBCF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158456_k127_3460247_2	391625.PPSIR1_24309	8.199e-26	121.0	COG0142@1|root,COG0142@2|Bacteria	2|Bacteria	H	isoprenoid biosynthetic process	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158456_k127_3460247_1	243231.GSU2781	1.652e-81	285.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,43TCG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SRR25158456_k127_3469103_3	1128421.JAGA01000003_gene2944	2.196e-177	569.0	COG1640@1|root,COG1640@2|Bacteria,2NP2W@2323|unclassified Bacteria	2|Bacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	iJN678.malQ	Glyco_hydro_77
SRR25158456_k127_3469103_1	760568.Desku_2853	4.173e-273	863.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,260ZW@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SRR25158456_k127_3469103_2	1121382.JQKG01000006_gene3396	1.047e-227	722.0	2DUWA@1|root,33SPG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3469103_4	192952.MM_0619	5.68e-169	558.0	COG1331@1|root,arCOG02007@2157|Archaea,2XU5Q@28890|Euryarchaeota,2N91Y@224756|Methanomicrobia	224756|Methanomicrobia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158456_k127_3469103_0	1122176.KB903554_gene4017	3.583e-300	958.0	COG4888@1|root,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
SRR25158456_k127_3469103_5	886293.Sinac_1729	8.368e-75	267.0	COG0501@1|root,COG0501@2|Bacteria,2J0GY@203682|Planctomycetes	203682|Planctomycetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158456_k127_3469391_0	1120999.JONM01000033_gene447	0.0	1480.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KQ86@206351|Neisseriales	206351|Neisseriales	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158456_k127_3478201_1	378806.STAUR_7328	3.523e-22	112.0	COG0189@1|root,COG0189@2|Bacteria,1RI0H@1224|Proteobacteria,4341G@68525|delta/epsilon subdivisions,2X4MX@28221|Deltaproteobacteria,2YZ9S@29|Myxococcales	28221|Deltaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158456_k127_3478201_0	502025.Hoch_5839	2.075e-222	712.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJEY@28221|Deltaproteobacteria,2YUDX@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158456_k127_3478890_2	1047013.AQSP01000123_gene1542	3.469e-41	156.0	COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_3478890_4	269799.Gmet_1056	5.843e-16	85.0	COG4914@1|root,COG4914@2|Bacteria,1N49U@1224|Proteobacteria,42WH5@68525|delta/epsilon subdivisions,2WRDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158456_k127_3478890_3	339670.Bamb_3413	4.696e-28	119.0	COG3554@1|root,COG3554@2|Bacteria,1N2WV@1224|Proteobacteria,2VXEY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158456_k127_3478890_0	1521187.JPIM01000015_gene3733	9.919e-106	370.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi,37528@32061|Chloroflexia	32061|Chloroflexia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158456_k127_3478890_1	941449.dsx2_2837	1.453e-43	162.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2WP2P@28221|Deltaproteobacteria,2MBQJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158456_k127_3488322_0	525904.Tter_1541	5.331e-106	350.0	COG0649@1|root,COG0649@2|Bacteria,2NNWG@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158456_k127_3488322_8	349741.Amuc_2158	7.27e-32	143.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158456_k127_3488322_1	479434.Sthe_0293	1.345e-66	242.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi,27XWB@189775|Thermomicrobia	189775|Thermomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158456_k127_3488322_10	935866.JAER01000013_gene1139	3.255e-16	84.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4DR0D@85009|Propionibacteriales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158456_k127_3488322_5	1121468.AUBR01000016_gene2299	5.368e-42	169.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,24GK7@186801|Clostridia,42I8X@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
SRR25158456_k127_3488322_6	926556.Echvi_0018	1.416e-41	162.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PDZ@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
SRR25158456_k127_3488322_4	1121859.KB890760_gene2033	6.573e-45	171.0	COG2885@1|root,COG2885@2|Bacteria,4NIY2@976|Bacteroidetes,47PC3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF937,OmpA
SRR25158456_k127_3488322_2	1282361.ABAC402_06880	3.474e-62	218.0	2D579@1|root,32TID@2|Bacteria,1RH2N@1224|Proteobacteria,2U9TR@28211|Alphaproteobacteria,2KIW3@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3488322_3	1192034.CAP_0501	2.156e-55	212.0	COG3386@1|root,COG3386@2|Bacteria,1QYGK@1224|Proteobacteria,437EJ@68525|delta/epsilon subdivisions,2X2KV@28221|Deltaproteobacteria,2Z04K@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3488322_9	404589.Anae109_2917	1.602e-24	108.0	COG3576@1|root,COG3576@2|Bacteria,1PT74@1224|Proteobacteria,432EH@68525|delta/epsilon subdivisions,2WXW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3488322_11	690585.JNNU01000010_gene761	3.024e-15	84.0	COG2203@1|root,COG2203@2|Bacteria,1PP8V@1224|Proteobacteria,2U4B8@28211|Alphaproteobacteria,4B7MK@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Putative_PNPOx
SRR25158456_k127_3495297_7	118168.MC7420_4742	3.426e-47	181.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
SRR25158456_k127_3495297_9	1144275.COCOR_05700	2.675e-37	145.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,437FF@68525|delta/epsilon subdivisions,2X2N2@28221|Deltaproteobacteria,2YZX8@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158456_k127_3495297_6	452637.Oter_2827	1.117e-50	202.0	COG1540@1|root,COG1540@2|Bacteria,46WDK@74201|Verrucomicrobia,3K8GD@414999|Opitutae	414999|Opitutae	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR25158456_k127_3495297_4	234267.Acid_4563	1.845e-116	389.0	COG0477@1|root,COG2814@2|Bacteria,3Y3ZZ@57723|Acidobacteria	57723|Acidobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_3495297_13	68194.JNXR01000003_gene3262	2.427e-28	134.0	COG4995@1|root,COG4995@2|Bacteria,2GT16@201174|Actinobacteria	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158456_k127_3495297_8	1220534.B655_0693	4.869e-45	181.0	arCOG03999@1|root,arCOG03999@2157|Archaea,2Y4KU@28890|Euryarchaeota	28890|Euryarchaeota	E	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SRR25158456_k127_3495297_0	1121015.N789_11890	8.297e-256	804.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RQGN@1236|Gammaproteobacteria,1X2YA@135614|Xanthomonadales	135614|Xanthomonadales	E	aminopeptidase n	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158456_k127_3495297_17	706587.Desti_2731	1.297e-05	57.0	COG1466@1|root,COG1466@2|Bacteria,1Q2BW@1224|Proteobacteria,437YE@68525|delta/epsilon subdivisions,2X38A@28221|Deltaproteobacteria,2MSDN@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	dna polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	-
SRR25158456_k127_3495297_16	204669.Acid345_4135	1.47e-21	98.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria,2JK2N@204432|Acidobacteriia	204432|Acidobacteriia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158456_k127_3495297_12	398767.Glov_3630	1.269e-28	121.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158456_k127_3495297_5	478741.JAFS01000001_gene1451	5.946e-65	237.0	COG2204@1|root,COG2204@2|Bacteria,46YV8@74201|Verrucomicrobia,37GDE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_3495297_15	1305732.JAGG01000001_gene1879	2.162e-23	114.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4FP5Z@85023|Microbacteriaceae	201174|Actinobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158456_k127_3495297_10	1043493.BBLU01000002_gene1868	3.228e-35	153.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158456_k127_3495297_3	289376.THEYE_A0433	5.595e-120	400.0	COG0536@1|root,COG0536@2|Bacteria,3J0E3@40117|Nitrospirae	40117|Nitrospirae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SRR25158456_k127_3495297_11	1499967.BAYZ01000165_gene6645	1.198e-32	129.0	COG0211@1|root,COG0211@2|Bacteria,2NPSU@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158456_k127_3495297_14	1254432.SCE1572_45530	4.843e-27	115.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2YVHC@29|Myxococcales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158456_k127_3495297_2	1047013.AQSP01000088_gene1631	7.935e-154	522.0	COG1629@1|root,COG1629@2|Bacteria,2NS4U@2323|unclassified Bacteria	2|Bacteria	P	PFAM TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_3495297_1	1382359.JIAL01000001_gene1070	8.301e-239	765.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria,2JIBH@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158456_k127_3500486_5	945713.IALB_1544	1.112e-29	134.0	COG3240@1|root,COG3240@2|Bacteria	2|Bacteria	I	lipase activity	-	-	-	ko:K15349	ko05132,map05132	-	-	-	ko00000,ko00001	-	-	-	Lipase_GDSL,Lipase_GDSL_2
SRR25158456_k127_3500486_3	1125863.JAFN01000001_gene829	1.036e-58	220.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
SRR25158456_k127_3500486_1	1121861.KB899911_gene1417	2.151e-147	487.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,2JPFI@204441|Rhodospirillales	204441|Rhodospirillales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158456_k127_3500486_4	316274.Haur_4216	3.282e-50	203.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158456_k127_3500486_2	225849.swp_3566	1.125e-119	398.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,2Q8YT@267890|Shewanellaceae	1236|Gammaproteobacteria	S	peptidase dimerisation domain protein	hipO	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158456_k127_3500486_6	240015.ACP_1829	2.039e-22	103.0	2DNS7@1|root,32YWC@2|Bacteria,3Y609@57723|Acidobacteria,2JK5C@204432|Acidobacteriia	204432|Acidobacteriia	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158456_k127_3500486_0	1254432.SCE1572_41890	1.177e-231	739.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales	28221|Deltaproteobacteria	G	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158456_k127_3527580_0	247490.KSU1_B0436	2.034e-68	259.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
SRR25158456_k127_3528334_0	84588.SYNW0985	4.637e-182	640.0	COG2931@1|root,COG3209@1|root,COG3898@1|root,COG5625@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3898@2|Bacteria,COG5625@2|Bacteria,1GJ0A@1117|Cyanobacteria,1H18T@1129|Synechococcus	1117|Cyanobacteria	Q	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
SRR25158456_k127_3528334_4	1283299.AUKG01000001_gene2130	2.486e-102	380.0	COG2206@1|root,COG2373@1|root,COG2206@2|Bacteria,COG2373@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158456_k127_3528334_8	1120963.KB894491_gene1242	1.228e-34	156.0	COG3209@1|root,COG3386@1|root,COG3209@2|Bacteria,COG3386@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,2Q5JA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF5122,He_PIG,PT-HINT,RHS_repeat
SRR25158456_k127_3528334_2	635013.TherJR_0997	1.399e-150	509.0	COG0395@1|root,COG5001@1|root,COG5002@1|root,COG0395@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,26021@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9
SRR25158456_k127_3528334_6	1382356.JQMP01000003_gene1698	5.435e-53	199.0	COG1680@1|root,COG1680@2|Bacteria,2GAJ8@200795|Chloroflexi,27YVH@189775|Thermomicrobia	189775|Thermomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_3528334_5	251221.35211462	2.789e-76	267.0	COG3291@1|root,COG3291@2|Bacteria,1GFMJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
SRR25158456_k127_3528334_1	269799.Gmet_1174	9.361e-157	539.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158456_k127_3528334_7	1379270.AUXF01000002_gene1135	8.596e-46	172.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_3528334_3	1183438.GKIL_3588	6.618e-129	423.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	pgcp	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158456_k127_3535891_2	1122604.JONR01000018_gene1064	1.256e-44	185.0	COG1716@1|root,COG1716@2|Bacteria,1R72N@1224|Proteobacteria,1S5IZ@1236|Gammaproteobacteria,1X6SR@135614|Xanthomonadales	135614|Xanthomonadales	T	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3535891_3	768706.Desor_4731	1.478e-08	68.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,261TT@186807|Peptococcaceae	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
SRR25158456_k127_3535891_1	234267.Acid_4318	3.833e-107	378.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158456_k127_3535891_0	1123508.JH636445_gene6642	7.065e-144	480.0	COG3827@1|root,COG3827@2|Bacteria,2IXVY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3543349_10	314345.SPV1_02432	1.468e-70	265.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,MASE4,PAS,PAS_3,PAS_9,Response_reg,dCache_1
SRR25158456_k127_3543349_13	1382359.JIAL01000001_gene1671	1.841e-43	183.0	COG0105@1|root,COG0105@2|Bacteria,3Y4MW@57723|Acidobacteria,2JJD4@204432|Acidobacteriia	204432|Acidobacteriia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158456_k127_3543349_14	1158165.KB898875_gene89	4.517e-27	128.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales	135613|Chromatiales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
SRR25158456_k127_3543349_4	663278.Ethha_2687	2.69e-177	570.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158456_k127_3543349_17	926692.AZYG01000056_gene440	0.0006473	47.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,24UDF@186801|Clostridia,3WC5V@53433|Halanaerobiales	186801|Clostridia	D	PFAM Septum formation initiator	-	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158456_k127_3543349_1	1123276.KB893247_gene178	7.81e-277	872.0	COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,47MK3@768503|Cytophagia	976|Bacteroidetes	S	glutamate carboxypeptidase	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
SRR25158456_k127_3543349_2	378806.STAUR_7640	2.324e-200	634.0	COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,4396X@68525|delta/epsilon subdivisions,2X4DR@28221|Deltaproteobacteria,2YYTQ@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,TPR_2
SRR25158456_k127_3543349_3	595536.ADVE02000001_gene850	2.822e-194	627.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,36Y0V@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_3543349_8	234267.Acid_3826	3.593e-73	280.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158456_k127_3543349_7	234267.Acid_3826	1.954e-87	309.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158456_k127_3543349_11	234267.Acid_5444	3.441e-68	263.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
SRR25158456_k127_3543349_12	234267.Acid_3826	5.248e-61	240.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
SRR25158456_k127_3543349_0	240015.ACP_2407	0.0	1089.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158456_k127_3543349_15	497964.CfE428DRAFT_6546	4.21e-22	105.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158456_k127_3543349_6	1353529.M899_0311	2.756e-111	381.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
SRR25158456_k127_3543349_9	1473546.CH76_11695	3.216e-72	248.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1TSJ8@1239|Firmicutes,4IQV9@91061|Bacilli	91061|Bacilli	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
SRR25158456_k127_3543349_5	1382359.JIAL01000001_gene773	5.895e-152	494.0	COG1027@1|root,COG1027@2|Bacteria,3Y3XS@57723|Acidobacteria,2JHYF@204432|Acidobacteriia	204432|Acidobacteriia	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158456_k127_3543349_16	1121920.AUAU01000019_gene2589	3.091e-19	96.0	COG1514@1|root,COG1514@2|Bacteria,3Y5S7@57723|Acidobacteria	57723|Acidobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158456_k127_3550887_3	1131269.AQVV01000001_gene1450	8.194e-44	169.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158456_k127_3550887_0	861299.J421_0764	4.677e-193	619.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_3550887_1	861299.J421_0763	2.367e-150	493.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_3550887_2	391625.PPSIR1_17395	1.13e-48	196.0	COG0515@1|root,COG0515@2|Bacteria	391625.PPSIR1_17395|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_355449_5	671143.DAMO_0319	2.577e-39	167.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158456_k127_355449_3	234267.Acid_5841	2.897e-50	192.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158456_k127_355449_4	1040989.AWZU01000054_gene3481	8.526e-45	173.0	28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,2U42A@28211|Alphaproteobacteria,3JTWI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
SRR25158456_k127_355449_0	264462.Bd3810	1.596e-159	513.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2MSP8@213481|Bdellovibrionales,2WJTS@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
SRR25158456_k127_355449_1	553217.ENHAE0001_1599	2.312e-101	355.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,3NKDR@468|Moraxellaceae	1236|Gammaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158456_k127_355449_8	1267535.KB906767_gene5290	1.706e-34	150.0	COG0288@1|root,COG0288@2|Bacteria,3Y7V2@57723|Acidobacteria,2JMYT@204432|Acidobacteriia	204432|Acidobacteriia	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158456_k127_355449_2	1379270.AUXF01000001_gene2605	1.702e-76	267.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_355449_10	558884.JRGM01000142_gene1661	1.842e-27	122.0	COG0300@1|root,COG0300@2|Bacteria,1MZSS@1224|Proteobacteria,1S9D8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_355449_12	1155718.KB891892_gene7014	1.989e-11	73.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158456_k127_355449_7	306281.AJLK01000039_gene3479	1.578e-36	148.0	COG4251@1|root,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria,1JK75@1189|Stigonemataceae	1117|Cyanobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY
SRR25158456_k127_355449_11	1432056.X781_23020	4.016e-24	108.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1S9P2@1236|Gammaproteobacteria,1YAT4@135625|Pasteurellales	135625|Pasteurellales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158456_k127_355449_9	420246.GTNG_0706	1.143e-30	132.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1WFBZ@129337|Geobacillus	91061|Bacilli	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
SRR25158456_k127_355449_6	861299.J421_3672	1.351e-38	157.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3562194_1	909663.KI867150_gene1810	3.081e-107	366.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2MRF6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158456_k127_3562194_3	1379698.RBG1_1C00001G1702	3.043e-29	127.0	COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158456_k127_3562194_0	648996.Theam_0942	7.387e-136	447.0	COG0151@1|root,COG0151@2|Bacteria,2G3J3@200783|Aquificae	200783|Aquificae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158456_k127_3562194_2	1089553.Tph_c08420	6.038e-47	175.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,42G1V@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158456_k127_356595_0	1247726.MIM_c34140	8.548e-169	547.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNB8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158456_k127_356595_2	331678.Cphamn1_0845	2.788e-41	161.0	COG1947@1|root,COG1947@2|Bacteria,1FDN3@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158456_k127_356595_1	1499967.BAYZ01000195_gene3095	2.729e-48	196.0	COG0457@1|root,COG0457@2|Bacteria,2NPEN@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
SRR25158456_k127_356595_3	5518.FGSG_01174P0	0.0009203	51.0	KOG1125@1|root,KOG1125@2759|Eukaryota,38C1T@33154|Opisthokonta,3NUGJ@4751|Fungi,3QK59@4890|Ascomycota,217D1@147550|Sordariomycetes,3TD53@5125|Hypocreales,1FU5R@110618|Nectriaceae	4751|Fungi	S	peroxisomal targeting signal receptor	PEX5	GO:0000268,GO:0003674,GO:0005048,GO:0005052,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016558,GO:0016560,GO:0017038,GO:0019395,GO:0019752,GO:0030258,GO:0030674,GO:0031090,GO:0031903,GO:0032787,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034440,GO:0034613,GO:0042277,GO:0042579,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043574,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045184,GO:0046395,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0055114,GO:0060090,GO:0065002,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0098588,GO:0098805,GO:1901575,GO:1990351,GO:1990415,GO:1990429	-	ko:K12261,ko:K13342	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000,ko04131	3.A.20.1	-	-	TPR_1,TPR_16,TPR_2,TPR_8
SRR25158456_k127_3569118_3	1429851.X548_13695	3.473e-11	63.0	COG0739@1|root,COG0739@2|Bacteria,1RK7E@1224|Proteobacteria,1RYS2@1236|Gammaproteobacteria,1X698@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158456_k127_3569118_0	1005048.CFU_3179	1.724e-206	661.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,2VP2M@28216|Betaproteobacteria,476SV@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Peptidase family M3	-	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158456_k127_3569118_4	220664.PFL_4030	1.522e-10	69.0	2E3S2@1|root,32YPN@2|Bacteria,1NDK1@1224|Proteobacteria,1SEFA@1236|Gammaproteobacteria,1YTYZ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_3569118_2	715226.ABI_09240	1.196e-24	108.0	COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,2UFFG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRR25158456_k127_3569118_1	1379270.AUXF01000003_gene3755	6.162e-39	167.0	28M10@1|root,2ZAFW@2|Bacteria,1ZSP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
SRR25158456_k127_3569741_2	234267.Acid_7205	1.9e-130	440.0	COG0751@1|root,COG0751@2|Bacteria,3Y3KN@57723|Acidobacteria	57723|Acidobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
SRR25158456_k127_3569741_3	526218.Sterm_3936	3.316e-127	414.0	COG0752@1|root,COG0752@2|Bacteria,3786U@32066|Fusobacteria	32066|Fusobacteria	J	Glycyl-tRNA synthetase alpha	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
SRR25158456_k127_3569741_8	1121935.AQXX01000139_gene3034	1.716e-18	92.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1XMA5@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158456_k127_3569741_0	215803.DB30_6992	1.315e-256	803.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions,2WM3R@28221|Deltaproteobacteria,2YX6W@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158456_k127_3569741_4	880073.Calab_3191	8.14e-117	381.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
SRR25158456_k127_3569741_5	234267.Acid_7701	6.932e-100	339.0	COG0719@1|root,COG0719@2|Bacteria,3Y4EK@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158456_k127_3569741_1	1382359.JIAL01000001_gene681	1.769e-171	569.0	COG0520@1|root,COG0520@2|Bacteria,3Y2SC@57723|Acidobacteria,2JKJX@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158456_k127_3569741_7	1283300.ATXB01000001_gene922	9.515e-53	189.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XF3J@135618|Methylococcales	135618|Methylococcales	C	TIGRFAM SUF system FeS	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158456_k127_3569741_6	1122604.JONR01000023_gene4160	2.214e-56	202.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1X3XG@135614|Xanthomonadales	135614|Xanthomonadales	S	FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158456_k127_357849_1	1209072.ALBT01000053_gene467	1.46e-62	233.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1FHR7@10|Cellvibrio	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8,SLH
SRR25158456_k127_357849_0	448385.sce3597	3.466e-115	386.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_366427_2	159087.Daro_0438	2.356e-73	271.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
SRR25158456_k127_366427_1	1499967.BAYZ01000184_gene4567	1.095e-238	761.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158456_k127_366427_0	1379270.AUXF01000004_gene3330	9.885e-251	788.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
SRR25158456_k127_366427_3	1094715.CM001373_gene2719	2.973e-40	153.0	2FEZ2@1|root,346XN@2|Bacteria,1P3U8@1224|Proteobacteria,1SS8E@1236|Gammaproteobacteria,1JEK0@118969|Legionellales	118969|Legionellales	-	-	icmD	-	-	ko:K12208	-	-	-	-	ko00000,ko02044	3.A.7.9.1	-	-	-
SRR25158456_k127_37851_6	67332.FM21_25180	1.826e-24	120.0	COG4122@1|root,COG4122@2|Bacteria,2GNMM@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158456_k127_37851_2	861299.J421_4151	8.655e-95	324.0	COG3182@1|root,COG3182@2|Bacteria,1ZUQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
SRR25158456_k127_37851_0	240016.ABIZ01000001_gene4736	2.12e-161	540.0	COG4774@1|root,COG4774@2|Bacteria,46U65@74201|Verrucomicrobia,2IWJI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
SRR25158456_k127_37851_1	379066.GAU_2727	1.024e-97	338.0	COG3128@1|root,COG3128@2|Bacteria	2|Bacteria	O	pkhd-type hydroxylase	piuC	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0033554,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
SRR25158456_k127_37851_3	1469557.JSWF01000014_gene2607	9.747e-82	284.0	COG0463@1|root,COG0463@2|Bacteria,4PNBB@976|Bacteroidetes,1I0HT@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_37851_7	1380763.BG53_07740	2.518e-09	70.0	28N1Z@1|root,2Z9N5@2|Bacteria,1V0S1@1239|Firmicutes,4HCNC@91061|Bacilli,27246@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_37851_5	1121930.AQXG01000003_gene2481	3.504e-53	208.0	28IBA@1|root,2Z8DT@2|Bacteria,4NI27@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
SRR25158456_k127_37851_4	1089548.KI783301_gene1163	5.122e-65	230.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,4HBRW@91061|Bacilli,3WF3I@539002|Bacillales incertae sedis	91061|Bacilli	M	Glycosyl transferases group 1	-	-	2.4.1.52	ko:K00712,ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT4	-	DUF3492,Glyco_trans_A_1,Glycos_transf_1
SRR25158456_k127_379309_4	1499967.BAYZ01000083_gene1034	4.682e-41	174.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SRR25158456_k127_379309_2	404380.Gbem_0747	8.793e-90	305.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,43UG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SRR25158456_k127_379309_0	378806.STAUR_8051	5.825e-147	480.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YYX2@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158456_k127_379309_5	134676.ACPL_1500	4.452e-26	122.0	2BXMW@1|root,32R1N@2|Bacteria,2I51F@201174|Actinobacteria,4DFQR@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_379309_1	479433.Caci_0493	1.687e-99	364.0	COG0455@1|root,COG5635@1|root,COG0455@2|Bacteria,COG5635@2|Bacteria,2GJIF@201174|Actinobacteria	201174|Actinobacteria	T	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SRR25158456_k127_379309_6	1449353.JQMQ01000005_gene2674	4.418e-07	64.0	2BXMW@1|root,32R1N@2|Bacteria,2I51F@201174|Actinobacteria,2NHNH@228398|Streptacidiphilus	201174|Actinobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_379309_3	236814.IX39_20335	7.981e-45	188.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
SRR25158456_k127_387167_2	883.DvMF_0698	4.97e-63	237.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,42NKX@68525|delta/epsilon subdivisions,2WVCN@28221|Deltaproteobacteria,2MG9V@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_387167_1	204669.Acid345_4024	2.332e-68	238.0	COG1309@1|root,COG1309@2|Bacteria,3Y5TS@57723|Acidobacteria,2JK51@204432|Acidobacteriia	204432|Acidobacteriia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158456_k127_387167_0	1267535.KB906767_gene3342	1.405e-157	519.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria,2JIF0@204432|Acidobacteriia	204432|Acidobacteriia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158456_k127_387167_3	1280390.CBQR020000073_gene1569	2.941e-41	165.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli	91061|Bacilli	P	Citrate transporter	ysdE	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SRR25158456_k127_387167_4	1157490.EL26_09620	1.912e-35	143.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,4HFJ0@91061|Bacilli,27A2P@186823|Alicyclobacillaceae	91061|Bacilli	G	BadF/BadG/BcrA/BcrD ATPase family	gspK	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158456_k127_389683_3	864051.BurJ1DRAFT_1242	1.067e-30	132.0	COG4412@1|root,COG4412@2|Bacteria,1R1VJ@1224|Proteobacteria	1224|Proteobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA
SRR25158456_k127_389683_0	84531.JMTZ01000039_gene544	1.869e-63	243.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD,Peptidase_S8
SRR25158456_k127_389683_1	1242864.D187_003367	2.234e-51	185.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158456_k127_389683_2	1128421.JAGA01000002_gene586	4.105e-43	175.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158456_k127_401328_1	626522.GCWU000325_01099	9.255e-58	212.0	COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,2FMGJ@200643|Bacteroidia,1WCPZ@1283313|Alloprevotella	976|Bacteroidetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158456_k127_401328_4	580332.Slit_2572	2.329e-09	60.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_401328_2	36875.HQ29_02695	7.981e-24	118.0	COG2095@1|root,COG2095@2|Bacteria,4NIHF@976|Bacteroidetes,2FMIJ@200643|Bacteroidia,22XS3@171551|Porphyromonadaceae	976|Bacteroidetes	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158456_k127_401328_0	330214.NIDE2086	1.619e-74	287.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158456_k127_401328_3	1306174.JODP01000006_gene2918	2.714e-19	103.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158456_k127_401791_0	1237149.C900_01925	0.0	2232.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,4NDV5@976|Bacteroidetes,47K9U@768503|Cytophagia	976|Bacteroidetes	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NAD_binding_4,PP-binding,Thioesterase,ketoacyl-synt
SRR25158456_k127_402392_5	395961.Cyan7425_1215	1.308e-79	277.0	28KJE@1|root,2ZA4F@2|Bacteria,1G3DZ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_402392_12	1123504.JQKD01000035_gene2697	2.352e-18	100.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,2VI30@28216|Betaproteobacteria,4AAB3@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158456_k127_402392_8	886293.Sinac_7219	4.337e-56	205.0	COG0745@1|root,COG0745@2|Bacteria,2IZ9J@203682|Planctomycetes	203682|Planctomycetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_402392_1	861299.J421_3650	1.791e-120	396.0	COG1131@1|root,COG1131@2|Bacteria,1ZTMK@142182|Gemmatimonadetes	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158456_k127_402392_6	861299.J421_3649	1.349e-79	286.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158456_k127_402392_4	926550.CLDAP_34310	4.365e-93	334.0	COG0745@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,2GBNT@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_402392_9	350058.Mvan_1710	1.852e-49	180.0	COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,23BI2@1762|Mycobacteriaceae	201174|Actinobacteria	S	PIN domain	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SRR25158456_k127_402392_11	525368.HMPREF0591_4504	4.082e-24	104.0	COG4691@1|root,COG4691@2|Bacteria,2HYH5@201174|Actinobacteria,23E5Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	RHH_1
SRR25158456_k127_402392_2	886293.Sinac_6489	1.064e-111	400.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
SRR25158456_k127_402392_7	1123242.JH636435_gene2613	2.823e-59	213.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158456_k127_402392_3	357808.RoseRS_2398	2.989e-110	362.0	COG0479@1|root,COG0479@2|Bacteria,2GACG@200795|Chloroflexi,3758X@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158456_k127_402392_0	357808.RoseRS_2399	2.707e-321	1001.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158456_k127_402392_10	1267533.KB906736_gene1088	1.78e-43	163.0	2CAZH@1|root,2Z7RU@2|Bacteria,3Y4WA@57723|Acidobacteria,2JKHZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
SRR25158456_k127_405774_1	397291.C804_00723	6.915e-17	96.0	COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,27J22@186928|unclassified Lachnospiraceae	186801|Clostridia	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,fn3
SRR25158456_k127_405774_0	1173027.Mic7113_1740	1.145e-62	223.0	COG3208@1|root,COG3208@2|Bacteria,1G16V@1117|Cyanobacteria,1H9TC@1150|Oscillatoriales	1117|Cyanobacteria	Q	thioesterase involved in non-ribosomal peptide biosynthesis	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Thioesterase
SRR25158456_k127_410280_4	1041146.ATZB01000028_gene5730	5.133e-42	157.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158456_k127_410280_0	700598.Niako_3710	1.623e-96	338.0	COG1752@1|root,COG1752@2|Bacteria,4P6IX@976|Bacteroidetes,1IZC5@117747|Sphingobacteriia	976|Bacteroidetes	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_410280_5	234267.Acid_7924	5.336e-34	144.0	2BMF1@1|root,32FZM@2|Bacteria,3Y8ZK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_410280_1	236814.IX39_20335	2.581e-96	336.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
SRR25158456_k127_410280_6	1121920.AUAU01000021_gene2512	2.922e-14	79.0	290IA@1|root,2ZN74@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_410280_3	472759.Nhal_0133	5.042e-59	214.0	COG4636@1|root,COG4636@2|Bacteria,1RH5Y@1224|Proteobacteria,1S823@1236|Gammaproteobacteria,1WYPU@135613|Chromatiales	135613|Chromatiales	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_410280_7	426117.M446_2803	1.656e-11	70.0	COG2114@1|root,COG2199@1|root,COG2114@2|Bacteria,COG3706@2|Bacteria,1QU6G@1224|Proteobacteria,2TW1I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HisKA,Response_reg
SRR25158456_k127_410280_2	1238182.C882_2849	2.12e-62	222.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,2JSCX@204441|Rhodospirillales	204441|Rhodospirillales	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH
SRR25158456_k127_420385_8	693977.Deipr_1937	8.365e-30	121.0	COG1028@1|root,COG1028@2|Bacteria,1WIPQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
SRR25158456_k127_420385_2	1121468.AUBR01000024_gene3021	1.321e-158	515.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158456_k127_420385_0	316274.Haur_4394	2.175e-235	751.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
SRR25158456_k127_420385_1	326427.Cagg_0348	2.88e-163	527.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158456_k127_420385_5	1122176.KB903532_gene2617	5.326e-75	260.0	COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,1IS4Y@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_420385_3	760192.Halhy_5620	4.213e-131	432.0	COG0477@1|root,COG2814@2|Bacteria,4PNZI@976|Bacteroidetes	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158456_k127_420385_9	138119.DSY1018	4.778e-10	65.0	COG2169@1|root,COG2169@2|Bacteria,1V3Y7@1239|Firmicutes,24FSV@186801|Clostridia,26304@186807|Peptococcaceae	186801|Clostridia	K	PFAM Metal binding domain of Ada	-	-	-	ko:K13530	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,HTH_18
SRR25158456_k127_420385_4	56107.Cylst_5525	6.75e-80	280.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158456_k127_420385_7	1304877.KI519399_gene5565	7.072e-30	132.0	COG4403@1|root,COG4403@2|Bacteria	2|Bacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158456_k127_420385_6	234267.Acid_6416	1.058e-70	266.0	COG4403@1|root,COG4403@2|Bacteria	2|Bacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like,VCBS
SRR25158456_k127_42819_2	746697.Aeqsu_3167	9.916e-61	220.0	COG2382@1|root,COG2382@2|Bacteria,4PP0A@976|Bacteroidetes	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158456_k127_42819_5	670487.Ocepr_0808	2.922e-05	56.0	COG0457@1|root,COG0640@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0640@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1WKHY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
SRR25158456_k127_42819_0	935863.AWZR01000001_gene1706	1.57e-88	308.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,1S57B@1236|Gammaproteobacteria,1X5IY@135614|Xanthomonadales	135614|Xanthomonadales	CG	Glycosyl transferases, related to UDP-glucuronosyltransferase	ugt	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
SRR25158456_k127_42819_1	483219.LILAB_25815	3.687e-78	274.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,4304Z@68525|delta/epsilon subdivisions,2WVJ8@28221|Deltaproteobacteria,2YV3F@29|Myxococcales	28221|Deltaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	topI	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158456_k127_42819_3	351160.RCIX211	1.54e-08	68.0	COG1807@1|root,arCOG03981@1|root,arCOG00566@2157|Archaea,arCOG03981@2157|Archaea,2Y4H0@28890|Euryarchaeota	28890|Euryarchaeota	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_42819_4	479434.Sthe_1779	3.026e-08	68.0	COG1807@1|root,COG1807@2|Bacteria,2GBE9@200795|Chloroflexi,27Z44@189775|Thermomicrobia	189775|Thermomicrobia	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SRR25158456_k127_429501_1	272123.Anacy_3669	2.986e-90	312.0	COG0438@1|root,COG0438@2|Bacteria,1G699@1117|Cyanobacteria,1HSFF@1161|Nostocales	1117|Cyanobacteria	M	SPTR Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158456_k127_429501_6	272123.Anacy_3666	9.682e-49	191.0	COG0382@1|root,COG0382@2|Bacteria,1GQKN@1117|Cyanobacteria,1HS8Z@1161|Nostocales	1117|Cyanobacteria	HQ	PFAM UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158456_k127_429501_11	497965.Cyan7822_1657	2.967e-12	78.0	2E40H@1|root,32YXB@2|Bacteria,1GG4B@1117|Cyanobacteria,3KK33@43988|Cyanothece	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158456_k127_429501_9	1380600.AUYN01000001_gene2288	9.345e-33	147.0	2AQ33@1|root,31F8A@2|Bacteria,4NPXX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_429501_0	1227739.Hsw_1587	6.714e-99	358.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47UTB@768503|Cytophagia	976|Bacteroidetes	GM	ATPases associated with a variety of cellular activities	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran
SRR25158456_k127_429501_7	35754.JNYJ01000052_gene6617	1.104e-39	172.0	COG2124@1|root,COG2124@2|Bacteria,2GNJI@201174|Actinobacteria,4DH45@85008|Micromonosporales	201174|Actinobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158456_k127_429501_8	1003195.SCAT_2817	1.441e-36	162.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158456_k127_429501_3	1174528.JH992898_gene1889	8.968e-60	217.0	COG1682@1|root,COG1682@2|Bacteria,1G234@1117|Cyanobacteria,1JJ9Q@1189|Stigonemataceae	1117|Cyanobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158456_k127_429501_5	497964.CfE428DRAFT_3066	1.491e-49	190.0	COG1216@1|root,COG1216@2|Bacteria,46VR2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_429501_10	314256.OG2516_14995	2.973e-25	121.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2TQJM@28211|Alphaproteobacteria,2PEVT@252301|Oceanicola	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_429501_2	946483.Cenrod_0505	1.851e-85	310.0	COG0438@1|root,COG0438@2|Bacteria,1R8CX@1224|Proteobacteria,2WF7X@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_429501_4	1045856.EcWSU1_03857	2.599e-58	210.0	2B632@1|root,31YZQ@2|Bacteria,1NRXY@1224|Proteobacteria,1T64D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_429501_12	234267.Acid_3898	3.315e-12	79.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	2|Bacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,VWA,VWA_2
SRR25158456_k127_429501_14	1382359.JIAL01000001_gene2531	3.253e-09	70.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria,2JHJT@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_429501_13	392499.Swit_4047	1.896e-10	71.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2UHNB@28211|Alphaproteobacteria,2K4Y8@204457|Sphingomonadales	204457|Sphingomonadales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB_2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SRR25158456_k127_430079_6	1282361.ABAC402_17950	2.135e-33	139.0	2C6NZ@1|root,335K8@2|Bacteria,1NDUY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_430079_1	240015.ACP_2502	1.134e-88	298.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_430079_2	1535422.ND16A_2589	2.798e-82	303.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,1RPKB@1236|Gammaproteobacteria,2Q618@267889|Colwelliaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_430079_4	1183438.GKIL_2517	9.678e-67	244.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_430079_3	1267533.KB906736_gene963	1.178e-78	285.0	2E7DT@1|root,32XVH@2|Bacteria,3Y712@57723|Acidobacteria,2JMBI@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158456_k127_430079_0	1267533.KB906736_gene962	2.458e-132	428.0	COG1131@1|root,COG1131@2|Bacteria,3Y7BR@57723|Acidobacteria,2JKD9@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_430079_5	1267533.KB906736_gene961	4.543e-48	175.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria,2JK5T@204432|Acidobacteriia	2|Bacteria	K	helix_turn_helix gluconate operon transcriptional repressor	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158456_k127_432240_1	1382359.JIAL01000001_gene1505	7.379e-129	415.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158456_k127_432240_7	236814.IX39_20375	0.0002746	48.0	COG0711@1|root,COG2319@1|root,COG0711@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	atpF	-	3.4.21.89	ko:K02109,ko:K03100,ko:K20444	ko00190,ko00195,ko01100,ko02024,ko03060,map00190,map00195,map01100,map02024,map03060	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000,ko01002,ko01005,ko02000	3.A.2.1,4.D.1.3	GT2,GT4	-	ATP-synt_B,DUF1863,Glyco_transf_4,Glycos_transf_2,TIR_2,WD40
SRR25158456_k127_432240_8	479433.Caci_4988	0.0003314	43.0	COG0277@1|root,COG0277@2|Bacteria,2GM6U@201174|Actinobacteria	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158456_k127_432240_4	1173028.ANKO01000193_gene5867	1.956e-24	121.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
SRR25158456_k127_432240_5	1530186.JQEY01000028_gene13	2.262e-08	68.0	COG4249@1|root,COG4249@2|Bacteria,1N2WM@1224|Proteobacteria,2UI00@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_432240_3	448385.sce6780	6.103e-67	235.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_432240_2	448385.sce2804	2.927e-87	302.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158456_k127_432240_0	448385.sce2805	0.0	1339.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158456_k127_432240_6	246197.MXAN_2932	7.462e-06	59.0	2DFGJ@1|root,2ZRS3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_43529_11	518766.Rmar_1205	8.353e-33	136.0	COG3332@1|root,COG3332@2|Bacteria,4NMX4@976|Bacteroidetes,1FJ9F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
SRR25158456_k127_43529_8	1961.JOAK01000016_gene5504	8.82e-76	267.0	COG3391@1|root,COG5492@1|root,COG3391@2|Bacteria,COG5492@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Cytochrom_D1,Lactonase
SRR25158456_k127_43529_0	1242864.D187_007079	5.395e-253	794.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_43529_1	1121930.AQXG01000005_gene577	3.02e-216	696.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,1IRBZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
SRR25158456_k127_43529_12	667014.Thein_0703	3.863e-25	106.0	COG1724@1|root,COG1724@2|Bacteria,2GIPV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158456_k127_43529_15	368407.Memar_1245	1.575e-19	89.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y1KD@28890|Euryarchaeota	28890|Euryarchaeota	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158456_k127_43529_6	1047013.AQSP01000056_gene1919	7.532e-88	303.0	COG0845@1|root,COG0845@2|Bacteria,2NR6A@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	VVA1500	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
SRR25158456_k127_43529_4	518766.Rmar_1441	5.236e-109	368.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_43529_5	518766.Rmar_1442	1.458e-98	337.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1FIY8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_43529_7	1219076.N646_1077	3.038e-87	293.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1XSYR@135623|Vibrionales	135623|Vibrionales	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_43529_9	234267.Acid_3412	1.83e-55	201.0	2BUWD@1|root,32Q8G@2|Bacteria	2|Bacteria	S	SatD family (SatD)	satD	-	-	-	-	-	-	-	-	-	-	-	SatD
SRR25158456_k127_43529_16	1122605.KB893644_gene1432	1.307e-16	92.0	COG0671@1|root,COG0671@2|Bacteria,4NF6Z@976|Bacteroidetes,1ITEY@117747|Sphingobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158456_k127_43529_2	234267.Acid_0997	1.377e-195	621.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD36	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087	-	ko:K12429,ko:K18660,ko:K18661,ko:K18662	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158456_k127_43529_10	1120949.KB903328_gene8858	2.482e-42	171.0	COG0457@1|root,COG0457@2|Bacteria,2IMH6@201174|Actinobacteria,4DI3R@85008|Micromonosporales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158456_k127_43529_14	479435.Kfla_3373	9.167e-21	108.0	28XC1@1|root,2ZJ9X@2|Bacteria,2H1HK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_43529_3	661478.OP10G_4395	2.682e-137	448.0	COG0465@1|root,COG0465@2|Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798,ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403,M00742	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03019,ko03110,ko04131,ko04147	3.A.16.1	-	-	AAA,Peptidase_M41,TPR_19,TPR_20
SRR25158456_k127_442968_3	1123242.JH636435_gene1562	1.767e-89	315.0	COG1118@1|root,COG1118@2|Bacteria,2J54I@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
SRR25158456_k127_442968_1	1156919.QWC_15979	1.076e-112	385.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,3T35W@506|Alcaligenaceae	28216|Betaproteobacteria	P	Sulfate ABC transporter, permease	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158456_k127_442968_2	859657.RPSI07_2022	1.388e-110	363.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,1K0GI@119060|Burkholderiaceae	28216|Betaproteobacteria	P	sulfate ABC transporter, inner membrane subunit CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
SRR25158456_k127_442968_0	1120973.AQXL01000115_gene650	1.992e-135	441.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,4HD5R@91061|Bacilli	91061|Bacilli	P	COG1613 ABC-type sulfate transport system, periplasmic component	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SRR25158456_k127_442968_4	1121887.AUDK01000020_gene2403	6.938e-10	64.0	COG4733@1|root,COG4733@2|Bacteria,4PPKU@976|Bacteroidetes,1I62W@117743|Flavobacteriia,2NZZ1@237|Flavobacterium	976|Bacteroidetes	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158456_k127_448326_4	1033730.CAHG01000006_gene1028	7.182e-28	114.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DQP2@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158456_k127_448326_8	56780.SYN_03595	0.0002962	43.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,42PXQ@68525|delta/epsilon subdivisions,2WKHU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158456_k127_448326_7	234267.Acid_3832	1.294e-08	62.0	2CIIF@1|root,30NI8@2|Bacteria,3Y8FJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_448326_3	1382359.JIAL01000001_gene404	1.844e-40	162.0	COG1595@1|root,COG1595@2|Bacteria,3Y87A@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158456_k127_448326_5	1267534.KB906757_gene1012	2.854e-14	81.0	290DP@1|root,2ZN31@2|Bacteria,3Y8WY@57723|Acidobacteria	57723|Acidobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158456_k127_448326_6	1267534.KB906757_gene1011	1.443e-09	68.0	28U6K@1|root,2ZGCA@2|Bacteria,3Y8UV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_448326_1	1267533.KB906733_gene3108	1.066e-99	355.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158456_k127_448326_0	1279038.KB907338_gene776	1.753e-311	991.0	COG0419@1|root,COG1112@1|root,COG0419@2|Bacteria,COG1112@2|Bacteria,1MW2R@1224|Proteobacteria,2TVCV@28211|Alphaproteobacteria,2JRGU@204441|Rhodospirillales	204441|Rhodospirillales	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
SRR25158456_k127_448326_2	35754.JNYJ01000083_gene4161	1.447e-59	214.0	COG1131@1|root,COG1131@2|Bacteria,2GNQJ@201174|Actinobacteria,4DHVM@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_456548_0	1125863.JAFN01000001_gene685	2.592e-72	251.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_456548_6	1121035.AUCH01000021_gene2720	4.806e-26	119.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,2VWQ0@28216|Betaproteobacteria,2KZCH@206389|Rhodocyclales	206389|Rhodocyclales	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
SRR25158456_k127_456548_2	1123371.ATXH01000018_gene1391	8.563e-52	189.0	COG2078@1|root,COG2078@2|Bacteria,2GH4V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
SRR25158456_k127_456548_4	224308.BSU21350	5.221e-36	148.0	COG0739@1|root,COG0741@1|root,COG1196@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,COG1196@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus	91061|Bacilli	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,PhageMin_Tail,SLT
SRR25158456_k127_456548_5	1121920.AUAU01000014_gene2832	3.152e-28	128.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LysM
SRR25158456_k127_456548_8	204669.Acid345_4769	1.235e-11	75.0	COG1579@1|root,COG1579@2|Bacteria,3Y509@57723|Acidobacteria,2JK0Q@204432|Acidobacteriia	204432|Acidobacteriia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158456_k127_456548_3	204669.Acid345_0088	1.837e-39	151.0	COG0328@1|root,COG0328@2|Bacteria,3Y4EY@57723|Acidobacteria,2JJ1U@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase-like	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158456_k127_456548_1	96561.Dole_1179	4.379e-54	200.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158456_k127_456548_9	1079460.ATTQ01000015_gene6554	9.981e-05	49.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,4BF92@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	integral membrane protein	MA20_25225	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158456_k127_456548_7	903818.KI912268_gene1138	1.387e-19	100.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	divIVA	-	-	ko:K04074,ko:K06997	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158456_k127_460047_2	1128427.KB904821_gene205	4.429e-116	398.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158456_k127_460047_0	401053.AciPR4_3595	2.489e-170	547.0	COG0535@1|root,COG0535@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158456_k127_460047_1	880073.Calab_0813	4.278e-128	445.0	COG1199@1|root,COG1199@2|Bacteria	2|Bacteria	L	ATP-dependent helicase activity	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
SRR25158456_k127_460047_3	504728.K649_02325	6.147e-25	106.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158456_k127_460476_1	204669.Acid345_1791	4.931e-12	67.0	COG1748@1|root,COG1748@2|Bacteria,3Y84N@57723|Acidobacteria	57723|Acidobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158456_k127_460476_0	446470.Snas_2659	3.878e-71	274.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158456_k127_460476_2	1267535.KB906767_gene1466	3.593e-05	53.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene1466|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_468807_1	756067.MicvaDRAFT_1008	3.883e-59	214.0	COG0400@1|root,COG0400@2|Bacteria,1G3RX@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase
SRR25158456_k127_468807_3	945713.IALB_0305	4.451e-26	121.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158456_k127_468807_2	671143.DAMO_0994	4.291e-30	126.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158456_k127_468807_0	269799.Gmet_2577	4.825e-150	482.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158456_k127_468807_4	1173264.KI913949_gene2865	6.288e-25	121.0	COG2442@1|root,COG2442@2|Bacteria,1G4E6@1117|Cyanobacteria,1H7IB@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_468807_5	755178.Cyan10605_0956	8.931e-08	60.0	2CNI4@1|root,32SH5@2|Bacteria,1G80S@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_469828_0	392500.Swoo_2854	1.032e-121	405.0	COG0457@1|root,COG0457@2|Bacteria,1PBYW@1224|Proteobacteria,1SWS0@1236|Gammaproteobacteria,2QDGR@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
SRR25158456_k127_469828_1	234267.Acid_2317	7.211e-86	295.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
SRR25158456_k127_469828_2	861299.J421_3788	3.587e-63	226.0	COG5637@1|root,COG5637@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
SRR25158456_k127_469828_4	1244869.H261_12854	8.22e-46	174.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,2JSP9@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
SRR25158456_k127_469828_6	323261.Noc_1108	4.359e-21	94.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_469828_7	631362.Thi970DRAFT_03342	8.982e-14	75.0	COG1724@1|root,COG1724@2|Bacteria,1NHPS@1224|Proteobacteria,1SGDT@1236|Gammaproteobacteria,1WZRG@135613|Chromatiales	135613|Chromatiales	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
SRR25158456_k127_469828_3	1321778.HMPREF1982_01776	1.544e-58	216.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158456_k127_469828_5	1040983.AXAE01000001_gene2731	4.619e-26	113.0	COG1522@1|root,COG1522@2|Bacteria,1RBPB@1224|Proteobacteria,2U6S5@28211|Alphaproteobacteria,43JJN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158456_k127_469828_8	1167006.UWK_00303	1.156e-08	60.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MI52@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SRR25158456_k127_477653_2	1121272.KB903290_gene4747	8.219e-60	217.0	2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_477653_10	65393.PCC7424_2842	0.000838	46.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,3KFSW@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158456_k127_477653_9	1137269.AZWL01000001_gene5673	0.0001328	55.0	COG0457@1|root,COG1672@1|root,COG3629@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG3629@2|Bacteria,2H1NS@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,NB-ARC,TPR_12,TPR_7,Trans_reg_C
SRR25158456_k127_477653_6	522306.CAP2UW1_2667	2.065e-14	84.0	28HTA@1|root,2Z806@2|Bacteria,1R7QM@1224|Proteobacteria,2W2CU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_477653_3	1121920.AUAU01000004_gene667	1.856e-59	233.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_477653_4	459349.CLOAM1897	2.599e-58	218.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_477653_1	1379270.AUXF01000005_gene457	3.764e-78	285.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_477653_0	1121920.AUAU01000004_gene664	1.171e-87	306.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158456_k127_477653_5	215803.DB30_5907	3.367e-29	119.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158456_k127_477653_7	1123276.KB893301_gene4243	3.057e-13	72.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,47PUA@768503|Cytophagia	976|Bacteroidetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158456_k127_477653_8	685727.REQ_40950	1.712e-08	57.0	COG2227@1|root,COG2227@2|Bacteria,2IIRY@201174|Actinobacteria,4FYEA@85025|Nocardiaceae	201174|Actinobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158456_k127_485421_3	861299.J421_3672	3.126e-61	217.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_485421_5	861299.J421_3671	4.622e-53	196.0	2F2ZI@1|root,33VUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_485421_2	861299.J421_3670	3.436e-66	251.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504	-	-	-	Beta-lactamase,Beta-lactamase2
SRR25158456_k127_485421_4	1343739.PAP_06205	1.743e-59	220.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,242SN@183968|Thermococci	183968|Thermococci	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158456_k127_485421_0	194439.CT2259	5.475e-95	318.0	COG2171@1|root,COG2171@2|Bacteria,1FDRM@1090|Chlorobi	1090|Chlorobi	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158456_k127_485421_1	589865.DaAHT2_2217	1.749e-82	283.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2MHXX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158456_k127_485421_6	1492738.FEM21_25730	1.05e-39	156.0	COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,1HX1D@117743|Flavobacteriia,2NSUN@237|Flavobacterium	976|Bacteroidetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158456_k127_48892_1	1279009.ADICEAN_00512	2.559e-228	728.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
SRR25158456_k127_48892_4	1254432.SCE1572_26550	5.487e-67	235.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158456_k127_48892_7	518766.Rmar_1861	1.04e-42	170.0	COG2972@1|root,COG2972@2|Bacteria,4NK4J@976|Bacteroidetes,1FIPJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SRR25158456_k127_48892_3	198094.BA_2183	1.092e-100	351.0	COG3227@1|root,COG3227@2|Bacteria,1TSGU@1239|Firmicutes,4HC7W@91061|Bacilli	91061|Bacilli	E	Peptidase M36	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PepSY,Peptidase_M36
SRR25158456_k127_48892_10	543632.JOJL01000024_gene2017	0.0002643	53.0	COG0412@1|root,COG0412@2|Bacteria,2I2QP@201174|Actinobacteria,4DEEA@85008|Micromonosporales	201174|Actinobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158456_k127_48892_11	1282360.ABAC460_05360	0.0003779	53.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2KIH3@204458|Caulobacterales	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Peptidase_M10_C
SRR25158456_k127_48892_9	1254432.SCE1572_44685	2.999e-10	63.0	COG0433@1|root,COG0433@2|Bacteria,1R2Z2@1224|Proteobacteria,43DI9@68525|delta/epsilon subdivisions,2X8PX@28221|Deltaproteobacteria,2Z21R@29|Myxococcales	2|Bacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
SRR25158456_k127_48892_2	1183438.GKIL_3422	1.204e-134	441.0	COG1228@1|root,COG1228@2|Bacteria,1G3PN@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158456_k127_48892_0	1123073.KB899241_gene3395	2.225e-248	775.0	COG0624@1|root,COG0624@2|Bacteria,1R96A@1224|Proteobacteria,1RSD6@1236|Gammaproteobacteria,1X5K9@135614|Xanthomonadales	135614|Xanthomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158456_k127_48892_8	1254432.SCE1572_49595	1.777e-15	88.0	28PVU@1|root,2ZCGC@2|Bacteria,1QT5D@1224|Proteobacteria,43570@68525|delta/epsilon subdivisions,2X96D@28221|Deltaproteobacteria,2Z272@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_48892_5	443143.GM18_0461	2.376e-53	199.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,42ZR0@68525|delta/epsilon subdivisions,2WT3B@28221|Deltaproteobacteria,43UQ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_48892_6	443143.GM18_0462	4.706e-44	179.0	COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158456_k127_490977_1	35754.JNYJ01000001_gene7520	3.23e-98	328.0	COG2755@1|root,COG2755@2|Bacteria,2GJUC@201174|Actinobacteria,4DI90@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158456_k127_490977_0	204669.Acid345_2144	1.36e-110	387.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria,2JIYW@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158456_k127_502114_7	349521.HCH_02260	3.819e-54	195.0	COG0662@1|root,COG0662@2|Bacteria,1RI2Z@1224|Proteobacteria,1S6BV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158456_k127_502114_6	196367.JNFG01000003_gene5632	1.65e-99	336.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2W1ES@28216|Betaproteobacteria,1K46J@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
SRR25158456_k127_502114_4	640510.BC1001_4637	5.817e-129	429.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2VPP0@28216|Betaproteobacteria,1K047@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158456_k127_502114_1	1380394.JADL01000009_gene3303	2.565e-199	627.0	COG0745@1|root,COG0745@2|Bacteria,1MX29@1224|Proteobacteria,2TV8G@28211|Alphaproteobacteria,2JPZF@204441|Rhodospirillales	204441|Rhodospirillales	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_502114_5	1040989.AWZU01000011_gene4136	9.207e-123	394.0	COG3391@1|root,COG3391@2|Bacteria,1N25Z@1224|Proteobacteria,2TUAK@28211|Alphaproteobacteria,3JUD4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	PQQ-like domain	MA20_01585	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2,PQQ_2
SRR25158456_k127_502114_0	450851.PHZ_c1067	0.0	1137.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1PTWJ@1224|Proteobacteria,2U237@28211|Alphaproteobacteria,2KG1X@204458|Caulobacterales	204458|Caulobacterales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158456_k127_502114_2	1550073.JROH01000003_gene2460	2.409e-151	482.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,2U2ZW@28211|Alphaproteobacteria,2K0PE@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_502114_8	1123242.JH636435_gene1286	5.666e-49	190.0	COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_502114_10	661478.OP10G_2515	7.822e-21	96.0	COG1725@1|root,COG1725@2|Bacteria	2|Bacteria	K	Transcriptional regulator	ytrA	-	-	ko:K07978,ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158456_k127_502114_3	1379270.AUXF01000007_gene963	2.382e-130	442.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158456_k127_502114_9	309807.SRU_1440	9.935e-45	170.0	COG2503@1|root,COG2503@2|Bacteria,4NJIJ@976|Bacteroidetes,1FJA7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRR25158456_k127_505540_1	378806.STAUR_0371	2.067e-76	267.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria	1224|Proteobacteria	F	Belongs to the IUNH family	iunH	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158456_k127_505540_0	714943.Mucpa_0607	2.316e-270	879.0	COG4630@1|root,COG4631@1|root,COG4630@2|Bacteria,COG4631@2|Bacteria,4PMEG@976|Bacteroidetes,1IPUS@117747|Sphingobacteriia	976|Bacteroidetes	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
SRR25158456_k127_506178_5	42565.FP66_14310	3.384e-35	147.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,1RRCA@1236|Gammaproteobacteria,1XI8F@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
SRR25158456_k127_506178_7	1278073.MYSTI_03701	6.185e-21	97.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	phcR	-	-	ko:K19622	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	HATPase_c,HDOD,Response_reg
SRR25158456_k127_506178_2	1297742.A176_00265	1.073e-67	253.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3
SRR25158456_k127_506178_0	330214.NIDE0781	4.352e-122	400.0	COG0462@1|root,COG0462@2|Bacteria,3J0D0@40117|Nitrospirae	40117|Nitrospirae	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158456_k127_506178_1	1242864.D187_006289	8.173e-98	326.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42T24@68525|delta/epsilon subdivisions,2WPF8@28221|Deltaproteobacteria,2YV09@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158456_k127_506178_8	715226.ABI_40010	1.593e-11	79.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2KGCY@204458|Caulobacterales	204458|Caulobacterales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158456_k127_506178_9	209285.XP_006696584.1	2.443e-07	65.0	KOG0315@1|root,KOG0315@2759|Eukaryota,38BGK@33154|Opisthokonta,3NTXM@4751|Fungi,3QMWX@4890|Ascomycota,216VF@147550|Sordariomycetes,3U8M9@5139|Sordariales,3HEQP@35718|Chaetomiaceae	4751|Fungi	S	WD domain, G-beta repeat	LST8	GO:0000139,GO:0001558,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005794,GO:0005829,GO:0005886,GO:0006996,GO:0007010,GO:0007154,GO:0007163,GO:0007165,GO:0008047,GO:0008150,GO:0009893,GO:0009898,GO:0009987,GO:0010008,GO:0010562,GO:0010604,GO:0012505,GO:0016020,GO:0016043,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0019897,GO:0019898,GO:0023052,GO:0030029,GO:0030036,GO:0030234,GO:0030295,GO:0030950,GO:0030952,GO:0031090,GO:0031234,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031410,GO:0031505,GO:0031929,GO:0031930,GO:0031931,GO:0031932,GO:0031974,GO:0031981,GO:0031982,GO:0031984,GO:0032147,GO:0032268,GO:0032270,GO:0032956,GO:0032970,GO:0032991,GO:0033043,GO:0033674,GO:0034399,GO:0035556,GO:0038201,GO:0040008,GO:0042325,GO:0042327,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043549,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045229,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051493,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0071554,GO:0071555,GO:0071840,GO:0071852,GO:0071944,GO:0080090,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098791,GO:0098805	-	ko:K08266	ko04136,ko04138,ko04140,ko04150,ko04151,ko04714,map04136,map04138,map04140,map04150,map04151,map04714	-	-	-	ko00000,ko00001,ko04131	-	-	-	WD40
SRR25158456_k127_506178_3	886293.Sinac_0410	9.223e-55	221.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
SRR25158456_k127_506178_4	1379698.RBG1_1C00001G0172	4.156e-38	151.0	COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria	2|Bacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158456_k127_506178_6	861299.J421_4267	1.083e-25	113.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158456_k127_50862_12	1128421.JAGA01000002_gene945	8.2e-48	179.0	COG1028@1|root,COG1028@2|Bacteria	1128421.JAGA01000002_gene945|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_50862_10	314230.DSM3645_06149	1.263e-59	222.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_50862_15	96561.Dole_2932	4.27e-09	65.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,42SG5@68525|delta/epsilon subdivisions,2WNPI@28221|Deltaproteobacteria,2MJX8@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM nuclease (SNase	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,Excalibur,SNase
SRR25158456_k127_50862_4	204669.Acid345_3116	3.951e-98	355.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_50862_6	288000.BBta_5484	5.112e-88	301.0	COG1864@1|root,COG3591@1|root,COG1864@2|Bacteria,COG3591@2|Bacteria,1QSGF@1224|Proteobacteria,2TTI7@28211|Alphaproteobacteria,3JQTM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EF	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS,Trypsin_2
SRR25158456_k127_50862_2	1242864.D187_005294	5.023e-138	449.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,437I2@68525|delta/epsilon subdivisions,2X2RH@28221|Deltaproteobacteria,2YVNV@29|Myxococcales	28221|Deltaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158456_k127_50862_5	886293.Sinac_6981	7.112e-97	345.0	COG1131@1|root,COG1131@2|Bacteria,2IYQP@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_50862_8	251221.35213677	3.299e-67	258.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,DUF3526
SRR25158456_k127_50862_3	1254432.SCE1572_08215	1.745e-119	404.0	COG1277@1|root,COG1277@2|Bacteria,1MW7Y@1224|Proteobacteria	1224|Proteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,DUF3526
SRR25158456_k127_50862_16	1108045.GORHZ_145_00130	5.688e-09	62.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_50862_13	1267534.KB906754_gene3312	5.086e-34	150.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158456_k127_50862_9	1267534.KB906754_gene3313	9.576e-61	223.0	COG0845@1|root,COG0845@2|Bacteria,3Y8NI@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158456_k127_50862_0	1278073.MYSTI_03564	0.0	1332.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WJ2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158456_k127_50862_7	234267.Acid_0024	1.372e-86	318.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
SRR25158456_k127_50862_11	1254432.SCE1572_01215	1.235e-49	182.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_50862_18	324925.Ppha_0358	1.716e-05	49.0	2DPDX@1|root,331PH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_50862_14	1487953.JMKF01000081_gene4233	1.986e-17	83.0	COG4118@1|root,COG4118@2|Bacteria,1G8FZ@1117|Cyanobacteria,1HDKF@1150|Oscillatoriales	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_50862_1	42256.RradSPS_0358	9.852e-140	477.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158456_k127_531081_2	1144275.COCOR_01290	3.551e-109	359.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YY4M@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158456_k127_531081_7	479434.Sthe_1779	6.462e-10	72.0	COG1807@1|root,COG1807@2|Bacteria,2GBE9@200795|Chloroflexi,27Z44@189775|Thermomicrobia	189775|Thermomicrobia	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SRR25158456_k127_531081_6	105425.BBPL01000004_gene7666	2.608e-14	79.0	COG1309@1|root,COG1309@2|Bacteria,2GNK4@201174|Actinobacteria,2NEPA@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158456_k127_531081_1	452637.Oter_1883	7.82e-153	513.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_531081_0	1242864.D187_000057	4.978e-288	902.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2YUNF@29|Myxococcales	28221|Deltaproteobacteria	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
SRR25158456_k127_531081_4	394221.Mmar10_0061	2.447e-35	148.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,2U9TM@28211|Alphaproteobacteria,4409A@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
SRR25158456_k127_531081_3	32049.SYNPCC7002_A2056	3.515e-52	195.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,1GZCJ@1129|Synechococcus	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
SRR25158456_k127_531081_5	497964.CfE428DRAFT_6546	1.527e-25	114.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158456_k127_538001_1	1254432.SCE1572_10940	1.741e-125	419.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,2YUUP@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
SRR25158456_k127_538001_7	1121920.AUAU01000007_gene502	5.078e-36	143.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
SRR25158456_k127_538001_6	391625.PPSIR1_36702	2.289e-69	238.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2YV2V@29|Myxococcales	28221|Deltaproteobacteria	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158456_k127_538001_8	903818.KI912268_gene3050	1.508e-26	113.0	COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158456_k127_538001_0	1382359.JIAL01000001_gene121	7.275e-210	705.0	COG1770@1|root,COG1770@2|Bacteria,3Y3PK@57723|Acidobacteria,2JIWT@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158456_k127_538001_2	33876.JNXY01000009_gene8908	3.421e-123	428.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulator	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
SRR25158456_k127_538001_3	1173024.KI912149_gene5854	8.583e-89	315.0	COG0457@1|root,COG0457@2|Bacteria,1GDHI@1117|Cyanobacteria	1117|Cyanobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_538001_4	1379270.AUXF01000002_gene1739	1.59e-81	278.0	COG0454@1|root,COG0456@2|Bacteria,1ZTIN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_538001_5	388413.ALPR1_06310	6.18e-81	280.0	COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes,47UKI@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158456_k127_547144_2	204669.Acid345_1750	2.472e-20	105.0	COG1324@1|root,COG1324@2|Bacteria,3Y5P7@57723|Acidobacteria,2JNJW@204432|Acidobacteriia	204432|Acidobacteriia	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158456_k127_547144_0	1121440.AUMA01000005_gene2519	1.21e-54	207.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria,2MBDA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SRR25158456_k127_547144_1	596151.DesfrDRAFT_3055	8.353e-33	136.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,2MG7G@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
SRR25158456_k127_556655_0	1297865.APJD01000003_gene6489	1.095e-89	312.0	COG0457@1|root,COG0457@2|Bacteria,1R6ZR@1224|Proteobacteria,2U1T5@28211|Alphaproteobacteria,3JWHB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
SRR25158456_k127_556655_1	272134.KB731324_gene5489	6.82e-05	47.0	2B73C@1|root,32049@2|Bacteria,1GKM3@1117|Cyanobacteria,1HG0W@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_556655_2	1123288.SOV_3c04610	0.0002536	51.0	COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes	1239|Firmicutes	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_557191_4	861299.J421_6231	1.815e-19	96.0	COG0491@1|root,COG0491@2|Bacteria,1ZU73@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_557191_0	1128421.JAGA01000002_gene1330	5.062e-71	258.0	COG2311@1|root,COG2311@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SRR25158456_k127_557191_6	237368.SCABRO_02625	0.000116	54.0	COG0457@1|root,COG0457@2|Bacteria	237368.SCABRO_02625|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_557191_3	448385.sce1328	6.842e-33	137.0	COG4276@1|root,COG4276@2|Bacteria,1R0BS@1224|Proteobacteria,43CU7@68525|delta/epsilon subdivisions,2X81U@28221|Deltaproteobacteria,2Z3JC@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158456_k127_557191_2	1173263.Syn7502_03141	7.965e-39	155.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	Methyltransf_25
SRR25158456_k127_557191_1	66429.JOFL01000006_gene2194	1.375e-55	204.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
SRR25158456_k127_557191_5	378806.STAUR_3665	1.881e-08	67.0	COG0399@1|root,COG0399@2|Bacteria,1REP8@1224|Proteobacteria,42S4Y@68525|delta/epsilon subdivisions,2WNVT@28221|Deltaproteobacteria,2YYWW@29|Myxococcales	28221|Deltaproteobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158456_k127_563096_1	504472.Slin_3863	4.031e-168	541.0	COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,47KQS@768503|Cytophagia	976|Bacteroidetes	M	membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
SRR25158456_k127_563096_6	1279009.ADICEAN_03014	6.762e-44	173.0	2B9IH@1|root,322WM@2|Bacteria,4NRND@976|Bacteroidetes,47QVN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_563096_3	1380390.JIAT01000009_gene2235	2.107e-114	382.0	COG3055@1|root,COG3055@2|Bacteria,2HQPC@201174|Actinobacteria,4CSAN@84995|Rubrobacteria	84995|Rubrobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_563096_4	111780.Sta7437_0767	1.252e-61	228.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,3VKTA@52604|Pleurocapsales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
SRR25158456_k127_563096_8	110319.CF8_2756	5.283e-19	99.0	2E0VD@1|root,32WCN@2|Bacteria,2ITDY@201174|Actinobacteria	201174|Actinobacteria	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
SRR25158456_k127_563096_9	518766.Rmar_1585	1.215e-13	82.0	COG1493@1|root,COG1493@2|Bacteria,4P7YQ@976|Bacteroidetes	976|Bacteroidetes	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_563096_7	1499967.BAYZ01000030_gene1170	7.813e-32	142.0	COG0535@1|root,COG0535@2|Bacteria,2NRPX@2323|unclassified Bacteria	2|Bacteria	S	Radical SAM superfamily	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SRR25158456_k127_563096_5	1499967.BAYZ01000186_gene3970	1.028e-59	228.0	COG0438@1|root,COG0438@2|Bacteria,2NR2T@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_563096_13	56110.Oscil6304_2088	0.0002115	50.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
SRR25158456_k127_563096_10	1112204.GPOL_c11350	7.282e-10	71.0	COG3307@1|root,COG3307@2|Bacteria,2HXH0@201174|Actinobacteria,4GFUR@85026|Gordoniaceae	201174|Actinobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158456_k127_563096_0	379066.GAU_3666	0.0	1294.0	COG0308@1|root,COG1277@1|root,COG0308@2|Bacteria,COG1277@2|Bacteria,1ZSMW@142182|Gemmatimonadetes	2|Bacteria	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1
SRR25158456_k127_563096_2	379066.GAU_3665	1.218e-150	480.0	COG1131@1|root,COG1131@2|Bacteria,1ZUJT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_564399_0	1123504.JQKD01000019_gene5545	5.019e-91	318.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,4AAG0@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158456_k127_564399_2	913865.DOT_1371	3.159e-40	158.0	COG0637@1|root,COG0637@2|Bacteria,1UW2W@1239|Firmicutes,25M3W@186801|Clostridia,2664X@186807|Peptococcaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158456_k127_564399_1	1192034.CAP_8739	1.272e-87	314.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42Z45@68525|delta/epsilon subdivisions,2WTWB@28221|Deltaproteobacteria,2YW9J@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HATPase_c,HisKA
SRR25158456_k127_575312_3	1443665.JACA01000013_gene4094	3.094e-12	68.0	COG2303@1|root,COG2303@2|Bacteria,4NJI1@976|Bacteroidetes,1I89K@117743|Flavobacteriia,2YHWR@290174|Aquimarina	976|Bacteroidetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_N,NAD_binding_8
SRR25158456_k127_575312_1	339670.Bamb_5930	2.152e-177	573.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2W1F4@28216|Betaproteobacteria,1KCH7@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
SRR25158456_k127_575312_2	1443665.JACA01000013_gene4093	1.229e-28	125.0	2EEEM@1|root,3388K@2|Bacteria,4NWYA@976|Bacteroidetes,1IA6U@117743|Flavobacteriia,2YH5I@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_575312_0	1192034.CAP_4376	1.079e-251	814.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria	2|Bacteria	Q	synthase	rhiB	-	-	ko:K13611,ko:K13613,ko:K13614,ko:K15675	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,NAD_binding_4,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_583981_3	1123401.JHYQ01000012_gene2956	4.09e-81	282.0	COG0834@1|root,COG0834@2|Bacteria,1P18B@1224|Proteobacteria,1T0T9@1236|Gammaproteobacteria,463D0@72273|Thiotrichales	72273|Thiotrichales	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SBP_bac_3
SRR25158456_k127_583981_1	1185876.BN8_04244	3.752e-136	451.0	COG1231@1|root,COG1231@2|Bacteria,4NJU7@976|Bacteroidetes,47NP2@768503|Cytophagia	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158456_k127_583981_4	502025.Hoch_5084	7.49e-77	263.0	COG1842@1|root,COG1842@2|Bacteria,1R9B6@1224|Proteobacteria	1224|Proteobacteria	KT	Phage shock protein A, PspA	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158456_k127_583981_0	1234364.AMSF01000025_gene3754	0.0	1446.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1X46E@135614|Xanthomonadales	135614|Xanthomonadales	L	Helicase	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158456_k127_583981_7	1192034.CAP_1140	6.257e-09	67.0	2A835@1|root,30X3P@2|Bacteria,1QB0X@1224|Proteobacteria,435DE@68525|delta/epsilon subdivisions,2WZR0@28221|Deltaproteobacteria,2Z2JH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_583981_8	290397.Adeh_2044	1.476e-06	61.0	2ANK3@1|root,31DJ6@2|Bacteria,1QAV7@1224|Proteobacteria,435BF@68525|delta/epsilon subdivisions,2WZNU@28221|Deltaproteobacteria,2Z2FP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_583981_2	861299.J421_6202	4.121e-98	331.0	COG1064@1|root,COG1064@2|Bacteria,1ZSXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158456_k127_583981_5	903818.KI912268_gene1906	3.888e-42	174.0	2D4UK@1|root,32THN@2|Bacteria,3Y59Q@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142
SRR25158456_k127_583981_6	1122169.AREN01000014_gene2671	2.297e-09	63.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158456_k127_594831_18	861299.J421_2643	0.0002689	46.0	COG1512@1|root,COG1512@2|Bacteria,1ZT1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158456_k127_594831_12	1122226.AUHX01000003_gene72	2.12e-32	131.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,1I266@117743|Flavobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
SRR25158456_k127_594831_15	552811.Dehly_0007	1.78e-25	112.0	COG0801@1|root,COG0801@2|Bacteria,2G6YT@200795|Chloroflexi,34D63@301297|Dehalococcoidia	301297|Dehalococcoidia	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158456_k127_594831_13	1121895.Q765_20080	2.884e-31	134.0	COG0739@1|root,COG0739@2|Bacteria,4NEBZ@976|Bacteroidetes,1HX9N@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3,SH3_4
SRR25158456_k127_594831_1	1123368.AUIS01000002_gene1533	1.315e-127	448.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,2NCCG@225057|Acidithiobacillales	225057|Acidithiobacillales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ChlI
SRR25158456_k127_594831_2	292459.STH1137	3.129e-109	364.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_594831_5	396014.BF93_15880	4.35e-76	261.0	COG1878@1|root,COG1878@2|Bacteria,2I66K@201174|Actinobacteria	201174|Actinobacteria	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158456_k127_594831_9	1242864.D187_008552	3.897e-39	149.0	COG2315@1|root,COG2315@2|Bacteria,1Q2G4@1224|Proteobacteria,4382J@68525|delta/epsilon subdivisions,2X3CK@28221|Deltaproteobacteria,2YVFB@29|Myxococcales	28221|Deltaproteobacteria	S	YjbR	difB	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158456_k127_594831_14	1121920.AUAU01000009_gene1864	6.959e-29	133.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_594831_0	886293.Sinac_7205	1.963e-253	810.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Cytochrome_P460,Glyco_hydro_26,PA14,RsgI_N
SRR25158456_k127_594831_6	1123277.KB893173_gene1883	1.488e-61	221.0	COG1226@1|root,COG1226@2|Bacteria,4NYQD@976|Bacteroidetes,47WHC@768503|Cytophagia	976|Bacteroidetes	P	Ion transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans
SRR25158456_k127_594831_4	234267.Acid_7054	1.072e-78	272.0	COG0077@1|root,COG0077@2|Bacteria,3Y49H@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158456_k127_594831_17	555779.Dthio_PD0418	3.08e-17	84.0	2EGU9@1|root,33AKF@2|Bacteria,1NJPN@1224|Proteobacteria,42XB8@68525|delta/epsilon subdivisions,2WT12@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
SRR25158456_k127_594831_16	1121405.dsmv_1532	7.229e-19	91.0	COG3668@1|root,COG3668@2|Bacteria,1N97P@1224|Proteobacteria,42VMQ@68525|delta/epsilon subdivisions,2WSAV@28221|Deltaproteobacteria,2MP9I@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158456_k127_594831_11	329726.AM1_4747	6.389e-34	143.0	COG1100@1|root,COG1100@2|Bacteria,1GC66@1117|Cyanobacteria	1117|Cyanobacteria	S	Ras of Complex, Roc, domain of DAPkinase	-	-	-	-	-	-	-	-	-	-	-	-	Ras
SRR25158456_k127_594831_10	1380387.JADM01000007_gene686	3.667e-38	147.0	2AXM7@1|root,31PMG@2|Bacteria,1RIYV@1224|Proteobacteria,1S732@1236|Gammaproteobacteria,1XKE9@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_594831_7	472759.Nhal_3404	5.153e-61	231.0	COG0640@1|root,COG1708@1|root,COG0640@2|Bacteria,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,1S3KC@1236|Gammaproteobacteria,1X2RI@135613|Chromatiales	135613|Chromatiales	K	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158456_k127_594831_3	1499967.BAYZ01000145_gene6209	5.673e-109	372.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR25158456_k127_594831_8	404589.Anae109_2915	4.377e-48	180.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_59939_24	426114.THI_2605	6.881e-08	64.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,1KNC7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158456_k127_59939_6	497964.CfE428DRAFT_2977	5.952e-85	301.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158456_k127_59939_9	380749.HY04AAS1_0509	9.831e-71	260.0	COG1028@1|root,COG1028@2|Bacteria,2G3IV@200783|Aquificae	200783|Aquificae	IQ	Short-chain dehydrogenase reductase SDR	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158456_k127_59939_5	1232410.KI421413_gene692	7.224e-98	334.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158456_k127_59939_4	370438.PTH_1746	3.639e-103	347.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158456_k127_59939_22	1267533.KB906734_gene4285	9.619e-20	95.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria,2JNN2@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal L32p protein family	-	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158456_k127_59939_21	644282.Deba_2394	4.06e-21	100.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158456_k127_59939_13	479434.Sthe_0904	1.348e-54	217.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_59939_16	479434.Sthe_0904	5.797e-44	173.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_59939_20	933262.AXAM01000069_gene2698	3.445e-31	135.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42N0S@68525|delta/epsilon subdivisions,2WJR0@28221|Deltaproteobacteria,2MK1F@213118|Desulfobacterales	28221|Deltaproteobacteria	H	metal-dependent phosphohydrolase HD sub	ccaC	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158456_k127_59939_8	397278.JOJN01000001_gene2741	9.541e-81	275.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4DPHV@85009|Propionibacteriales	201174|Actinobacteria	Q	Domain of unknown function (DUF2437)	fahA	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158456_k127_59939_15	445973.CLOBAR_02853	2.097e-48	179.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25RBZ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158456_k127_59939_12	1300345.LF41_1425	2.802e-62	231.0	COG2755@1|root,COG2755@2|Bacteria,1RE1B@1224|Proteobacteria,1S3DM@1236|Gammaproteobacteria,1X613@135614|Xanthomonadales	135614|Xanthomonadales	E	Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158456_k127_59939_10	215803.DB30_8136	4.674e-70	254.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2YVGU@29|Myxococcales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158456_k127_59939_1	338966.Ppro_0383	1.364e-168	546.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,43U97@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158456_k127_59939_0	511051.CSE_10010	1.933e-176	567.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158456_k127_59939_17	794903.OPIT5_19020	4.753e-39	155.0	COG1169@1|root,COG1943@1|root,COG1169@2|Bacteria,COG1943@2|Bacteria,46TTI@74201|Verrucomicrobia,3K7NU@414999|Opitutae	414999|Opitutae	HQ	Isochorismate synthase	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158456_k127_59939_3	518766.Rmar_0322	8.52e-121	407.0	COG0699@1|root,COG0699@2|Bacteria,4NTQB@976|Bacteroidetes,1FJXE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158456_k127_59939_18	706587.Desti_3996	1.947e-37	153.0	COG1597@1|root,COG1597@2|Bacteria,1QH8J@1224|Proteobacteria,42Y04@68525|delta/epsilon subdivisions,2WSRW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158456_k127_59939_14	666686.B1NLA3E_19985	9.483e-54	209.0	COG1705@1|root,COG4193@1|root,COG1705@2|Bacteria,COG4193@2|Bacteria,1UT0U@1239|Firmicutes,4HB90@91061|Bacilli,1ZEHX@1386|Bacillus	91061|Bacilli	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3,SLH
SRR25158456_k127_59939_7	198628.Dda3937_02989	7.915e-82	303.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria,2JEW2@204037|Dickeya	1236|Gammaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_59939_2	479434.Sthe_0425	5.407e-140	459.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,27XS9@189775|Thermomicrobia	189775|Thermomicrobia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
SRR25158456_k127_59939_11	935839.JAGJ01000003_gene1601	5.4e-67	240.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,CW_binding_2,Lysyl_oxidase,PLDc_2,Peptidase_C70,Stig1,Trypsin,Trypsin_2
SRR25158456_k127_59939_23	1121403.AUCV01000119_gene434	3.394e-13	77.0	COG3209@1|root,COG3209@2|Bacteria,1N9RU@1224|Proteobacteria	1224|Proteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS
SRR25158456_k127_602097_7	1380347.JNII01000005_gene3610	7.683e-09	66.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	ko:K02200,ko:K04018	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19
SRR25158456_k127_602097_6	1167006.UWK_00876	2.991e-24	109.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
SRR25158456_k127_602097_4	1379270.AUXF01000003_gene3469	2.498e-44	171.0	COG1376@1|root,COG1376@2|Bacteria,1ZUFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158456_k127_602097_8	518766.Rmar_0611	1.744e-08	64.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158456_k127_602097_1	1379698.RBG1_1C00001G0109	1.864e-97	325.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158456_k127_602097_0	234267.Acid_0826	1.198e-108	359.0	COG0803@1|root,COG0803@2|Bacteria,3Y97A@57723|Acidobacteria	57723|Acidobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158456_k127_602097_2	234267.Acid_0825	2.672e-75	268.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_602097_5	1237149.C900_03646	6.361e-38	145.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,47QDT@768503|Cytophagia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158456_k127_602097_3	357808.RoseRS_0616	4.39e-65	241.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158456_k127_606998_0	1191523.MROS_0693	3.092e-218	696.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158456_k127_606998_8	1397666.RS24_00794	2.684e-58	214.0	COG0500@1|root,COG2226@2|Bacteria,1RERY@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158456_k127_606998_4	414684.RC1_3768	1.396e-106	359.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,2U5PV@28211|Alphaproteobacteria,2JU2N@204441|Rhodospirillales	204441|Rhodospirillales	M	Cytidylyltransferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
SRR25158456_k127_606998_1	489825.LYNGBM3L_52650	7.754e-216	679.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,1H7AN@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158456_k127_606998_10	502025.Hoch_0344	2.727e-56	216.0	COG1028@1|root,COG1028@2|Bacteria,1Q3GM@1224|Proteobacteria,42SZ6@68525|delta/epsilon subdivisions,2WP46@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158456_k127_606998_11	316055.RPE_4240	4.757e-47	190.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria	1224|Proteobacteria	M	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	2.7.7.43,2.7.7.92,3.1.3.45	ko:K03270,ko:K21749	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase,Hydrolase_3
SRR25158456_k127_606998_3	102232.GLO73106DRAFT_00033450	7.854e-145	491.0	COG2089@1|root,COG2089@2|Bacteria,1G78N@1117|Cyanobacteria	1117|Cyanobacteria	M	synthase	spsE	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
SRR25158456_k127_606998_13	1441629.PCH70_17990	4.666e-19	102.0	COG2244@1|root,COG2244@2|Bacteria,1RIXW@1224|Proteobacteria,1RQP6@1236|Gammaproteobacteria,1Z61Y@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
SRR25158456_k127_606998_12	316055.RPE_4247	8.161e-37	158.0	COG1216@1|root,COG4122@1|root,COG1216@2|Bacteria,COG4122@2|Bacteria,1N2TQ@1224|Proteobacteria,2UEGJ@28211|Alphaproteobacteria,3K28G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
SRR25158456_k127_606998_5	1267005.KB911257_gene665	2.779e-100	348.0	COG3510@1|root,COG3510@2|Bacteria,1MWJ8@1224|Proteobacteria,2U3D6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	cephalosporin hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	CmcI
SRR25158456_k127_606998_6	555779.Dthio_PD1565	2.379e-67	245.0	COG0451@1|root,COG0451@2|Bacteria,1RH07@1224|Proteobacteria	1224|Proteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158456_k127_606998_9	1121004.ATVC01000064_gene1620	4.094e-57	205.0	COG0110@1|root,COG0110@2|Bacteria,1RAIP@1224|Proteobacteria,2VXZE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158456_k127_606998_7	395493.BegalDRAFT_2269	1.464e-60	231.0	COG1898@1|root,COG1898@2|Bacteria,1RDAB@1224|Proteobacteria,1S5T5@1236|Gammaproteobacteria,462QJ@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158456_k127_606998_2	1123368.AUIS01000027_gene1343	1.512e-172	551.0	COG0500@1|root,COG0500@2|Bacteria,1MVD1@1224|Proteobacteria,1RZDA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158456_k127_610933_2	318167.Sfri_0263	1.775e-63	227.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2QB1M@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158456_k127_610933_4	215803.DB30_4282	1.906e-24	105.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria,2Z339@29|Myxococcales	28221|Deltaproteobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158456_k127_610933_0	1144275.COCOR_06393	2.382e-181	582.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	fabB	-	2.3.1.179,2.3.1.180	ko:K09458,ko:K18473	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00082,M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119,R10707	RC00004,RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158456_k127_610933_3	379066.GAU_0513	1.617e-31	141.0	COG2027@1|root,COG2027@2|Bacteria,1ZT1Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158456_k127_610933_1	861299.J421_0601	1.324e-110	387.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_619805_9	658612.MD26_23085	2.235e-07	59.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158456_k127_619805_0	857087.Metme_2588	2.871e-104	363.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XDJ5@135618|Methylococcales	135618|Methylococcales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158456_k127_619805_8	1125863.JAFN01000001_gene2289	4.99e-17	92.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158456_k127_619805_2	1160137.KB907308_gene6726	6.766e-50	198.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4FWPS@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158456_k127_619805_5	1123073.KB899243_gene666	1.048e-42	160.0	2CX7C@1|root,32T1D@2|Bacteria,1N2N3@1224|Proteobacteria,1S4YA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_619805_3	861299.J421_4133	1.402e-47	177.0	2CB8S@1|root,30PE6@2|Bacteria,1ZV1Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
SRR25158456_k127_619805_6	204669.Acid345_2902	1.889e-42	164.0	COG2197@1|root,COG2197@2|Bacteria,3Y60I@57723|Acidobacteria,2JKWI@204432|Acidobacteriia	204432|Acidobacteriia	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158456_k127_619805_1	234267.Acid_2379	4.42e-57	229.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,3Y5S6@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158456_k127_620347_4	716544.wcw_1030	8.649e-32	132.0	COG0318@1|root,COG0318@2|Bacteria,2JFYB@204428|Chlamydiae	204428|Chlamydiae	IQ	AMP-binding enzyme	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding
SRR25158456_k127_620347_3	349741.Amuc_1816	9.572e-44	179.0	COG4948@1|root,COG4948@2|Bacteria,46X7I@74201|Verrucomicrobia,2IUF3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mandelate Racemase Muconate Lactonizing	-	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
SRR25158456_k127_620347_1	1242864.D187_007605	3.108e-73	258.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S4J@68525|delta/epsilon subdivisions,2WNH4@28221|Deltaproteobacteria,2YTUZ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158456_k127_620347_0	1396141.BATP01000045_gene1741	2.227e-136	437.0	COG0447@1|root,COG0447@2|Bacteria,46Z3Z@74201|Verrucomicrobia,2ITPX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Enoyl-CoA hydratase/isomerase	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158456_k127_620347_5	1123070.KB899249_gene437	1.328e-24	119.0	COG2267@1|root,COG2267@2|Bacteria,46WQX@74201|Verrucomicrobia,2IUN2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Alpha/beta hydrolase family	-	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SRR25158456_k127_620347_2	765952.PUV_20300	6.985e-64	230.0	COG1165@1|root,COG1165@2|Bacteria,2JG2A@204428|Chlamydiae	204428|Chlamydiae	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158456_k127_620972_0	1144275.COCOR_00357	6.694e-110	368.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2YUN4@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Response_reg,RsbRD_N,SBP_bac_3
SRR25158456_k127_620972_5	671143.DAMO_0140	2.56e-25	107.0	COG1278@1|root,COG1278@2|Bacteria,2NPXP@2323|unclassified Bacteria	2|Bacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158456_k127_620972_3	1347369.CCAD010000036_gene1125	1.996e-48	181.0	COG2353@1|root,COG2353@2|Bacteria,1V1NX@1239|Firmicutes,4HFXF@91061|Bacilli,1ZCU9@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158456_k127_620972_1	1121013.P873_05180	2.327e-71	247.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,1S3KC@1236|Gammaproteobacteria,1X5GB@135614|Xanthomonadales	135614|Xanthomonadales	K	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,NTP_transf_2
SRR25158456_k127_620972_4	1120999.JONM01000021_gene104	9.289e-34	137.0	2AXM7@1|root,31PMG@2|Bacteria,1RIYV@1224|Proteobacteria,2VUMG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_620972_2	395494.Galf_1478	9.647e-57	203.0	COG5340@1|root,COG5340@2|Bacteria,1P6MT@1224|Proteobacteria,2VPJY@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158456_k127_624172_5	1523503.JPMY01000002_gene3862	7.063e-69	246.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,1S3V3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FJ	deaminase	cdd	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158456_k127_624172_7	1211814.CAPG01000031_gene1481	6.671e-34	142.0	COG0739@1|root,COG0739@2|Bacteria,1V2IA@1239|Firmicutes,4HG3A@91061|Bacilli,1ZQU0@1386|Bacillus	91061|Bacilli	M	Peptidase family M23	yebA5	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158456_k127_624172_12	381666.H16_A1662	0.0001528	51.0	COG4568@1|root,COG4568@2|Bacteria,1NKDC@1224|Proteobacteria,2W48P@28216|Betaproteobacteria,1KEK0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	rho-dependent transcription termination	-	-	-	ko:K19000	-	-	-	-	ko00000,ko03021	-	-	-	-
SRR25158456_k127_624172_11	1463900.JOIX01000021_gene7267	7.643e-09	68.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
SRR25158456_k127_624172_9	1089547.KB913013_gene3391	1.445e-10	65.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
SRR25158456_k127_624172_0	290397.Adeh_2523	0.0	1126.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YXKT@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158456_k127_624172_10	1297742.A176_05743	1.006e-09	65.0	COG1011@1|root,COG1011@2|Bacteria,1RA0T@1224|Proteobacteria	1224|Proteobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_624172_1	323850.Shew_0033	1.797e-188	605.0	COG2866@1|root,COG2866@2|Bacteria,1QHMD@1224|Proteobacteria,1RYUG@1236|Gammaproteobacteria,2Q9QW@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158456_k127_624172_8	1449049.JONW01000011_gene2113	8.743e-12	77.0	COG3667@1|root,COG3667@2|Bacteria,1R6TA@1224|Proteobacteria,2U52R@28211|Alphaproteobacteria,2KG6I@204458|Caulobacterales	204458|Caulobacterales	P	copper resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_624172_6	66429.JOFL01000006_gene2116	2.744e-50	199.0	2DP7T@1|root,330W7@2|Bacteria,2IH3C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_624172_2	1121920.AUAU01000013_gene1712	3.362e-120	400.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_624172_3	1121920.AUAU01000013_gene1713	5.566e-102	362.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_624172_4	1121920.AUAU01000013_gene1714	3.582e-97	332.0	COG0845@1|root,COG0845@2|Bacteria,3Y2XR@57723|Acidobacteria	57723|Acidobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158456_k127_627971_0	330214.NIDE1908	2.14e-90	312.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
SRR25158456_k127_627971_3	134676.ACPL_3179	2.416e-10	72.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158456_k127_646473_0	1163408.UU9_02399	1.867e-137	477.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,1XCVX@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158456_k127_646473_1	796606.BMMGA3_07100	4.247e-50	185.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_25
SRR25158456_k127_646816_9	521674.Plim_3486	1.444e-15	77.0	COG0008@1|root,COG0008@2|Bacteria,2IYSE@203682|Planctomycetes	203682|Planctomycetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
SRR25158456_k127_646816_2	497964.CfE428DRAFT_0572	2.078e-87	304.0	COG3488@1|root,COG3488@2|Bacteria,46T3U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
SRR25158456_k127_646816_3	1128421.JAGA01000002_gene189	5.83e-73	259.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2NR1B@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	yhcY	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158456_k127_646816_5	316274.Haur_1309	7.982e-40	163.0	COG2197@1|root,COG2197@2|Bacteria,2G6JC@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158456_k127_646816_6	240016.ABIZ01000001_gene261	5.914e-30	130.0	COG5654@1|root,COG5654@2|Bacteria	2|Bacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158456_k127_646816_4	1380347.JNII01000006_gene1215	1.36e-52	195.0	COG1028@1|root,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4EUIE@85013|Frankiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_646816_1	1121377.KB906405_gene135	1.594e-95	347.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158456_k127_646816_0	215803.DB30_7179	1.203e-239	760.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,42YQP@68525|delta/epsilon subdivisions,2WTJM@28221|Deltaproteobacteria,2YY5X@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158456_k127_646816_7	1521187.JPIM01000026_gene1160	2.869e-20	106.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158456_k127_646816_10	1357272.AVEO02000170_gene2318	4.732e-08	66.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria,1Z68Q@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	DNA-binding heavy metal response regulator	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_647246_3	1071679.BG57_05160	7.452e-88	303.0	28MCN@1|root,2ZAQR@2|Bacteria,1N00X@1224|Proteobacteria,2VV0N@28216|Betaproteobacteria,1KDZ7@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_647246_2	1081640.AGFU01000044_gene552	2.225e-89	313.0	COG3023@1|root,COG3179@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3179@2|Bacteria,COG3409@2|Bacteria,1RC1P@1224|Proteobacteria,2U5PY@28211|Alphaproteobacteria,2K7PA@204457|Sphingomonadales	204457|Sphingomonadales	V	Glycoside hydrolase, family 19	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,PG_binding_1
SRR25158456_k127_647246_0	861299.J421_1732	0.0	1404.0	COG0308@1|root,COG0308@2|Bacteria,1ZSMW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158456_k127_647246_1	861299.J421_1733	8.859e-146	468.0	COG1131@1|root,COG1131@2|Bacteria,1ZUJT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_647246_8	83219.PM02_18690	0.0001622	52.0	2E5S2@1|root,330GK@2|Bacteria,1N91G@1224|Proteobacteria,2UGF6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_647246_4	485918.Cpin_3474	1.908e-36	154.0	COG1502@1|root,COG1502@2|Bacteria,4NPTM@976|Bacteroidetes,1IXI9@117747|Sphingobacteriia	976|Bacteroidetes	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158456_k127_647246_5	1278073.MYSTI_07197	2.262e-28	132.0	2DBR9@1|root,2ZAJD@2|Bacteria,1R7F3@1224|Proteobacteria,435AD@68525|delta/epsilon subdivisions,2WZME@28221|Deltaproteobacteria,2Z2DE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_647246_6	134676.ACPL_2029	1.288e-10	74.0	COG4995@1|root,COG4995@2|Bacteria,2ICQB@201174|Actinobacteria,4DKGW@85008|Micromonosporales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CHAT,Peptidase_S8,WD40
SRR25158456_k127_647246_7	1128421.JAGA01000002_gene1985	2.614e-05	54.0	COG0823@1|root,COG4995@1|root,COG0823@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CHAT,PD40,WD40
SRR25158456_k127_647458_1	290397.Adeh_2722	2.577e-56	213.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158456_k127_647458_4	665571.STHERM_c06610	9.399e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,2J5PC@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
SRR25158456_k127_647458_3	1267534.KB906759_gene2009	1.437e-12	76.0	29CGV@1|root,2ZZF9@2|Bacteria,3Y4JX@57723|Acidobacteria,2JJ9Y@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SRR25158456_k127_647458_0	1382359.JIAL01000001_gene2644	6.929e-72	252.0	COG0412@1|root,COG0412@2|Bacteria,3Y4P0@57723|Acidobacteria,2JJCI@204432|Acidobacteriia	204432|Acidobacteriia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158456_k127_647458_2	338966.Ppro_2752	7.696e-39	159.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,43VBU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_659178_2	1227739.Hsw_2761	1.961e-86	298.0	28HGI@1|root,2Z7SC@2|Bacteria,4NJUF@976|Bacteroidetes,47PDE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_659178_3	1278073.MYSTI_07058	4.253e-49	201.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SRR25158456_k127_659178_1	765913.ThidrDRAFT_0644	4.607e-92	317.0	COG1672@1|root,COG1672@2|Bacteria,1R8WY@1224|Proteobacteria,1S0C0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_659178_0	765913.ThidrDRAFT_0643	7.583e-148	489.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1MVMG@1224|Proteobacteria,1RR2P@1236|Gammaproteobacteria,1WVXQ@135613|Chromatiales	135613|Chromatiales	O	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_668465_2	234267.Acid_7887	3.862e-65	229.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria	57723|Acidobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158456_k127_668465_4	469383.Cwoe_3355	3.624e-42	163.0	COG3832@1|root,COG3832@2|Bacteria,2IQUJ@201174|Actinobacteria	201174|Actinobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_668465_1	1122604.JONR01000009_gene2348	2.326e-68	246.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,1S43N@1236|Gammaproteobacteria,1X64X@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YaeQ
SRR25158456_k127_668465_8	935567.JAES01000020_gene583	1.357e-14	81.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,1S6E9@1236|Gammaproteobacteria,1X8JP@135614|Xanthomonadales	135614|Xanthomonadales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
SRR25158456_k127_668465_9	1121007.AUML01000002_gene1721	2.729e-13	74.0	COG1225@1|root,COG1225@2|Bacteria,4NKV2@976|Bacteroidetes,1HZ0U@117743|Flavobacteriia,2YM4K@290174|Aquimarina	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158456_k127_668465_10	497964.CfE428DRAFT_2653	1.71e-05	55.0	2ECUE@1|root,336RY@2|Bacteria,46TBJ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_668465_7	398767.Glov_3583	3.787e-18	93.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,43DNJ@68525|delta/epsilon subdivisions,2X6KT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158456_k127_668465_6	324602.Caur_0352	3.435e-27	128.0	COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi,375N6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158456_k127_668465_3	215803.DB30_1448	1.187e-51	195.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria,2YVHM@29|Myxococcales	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158456_k127_668465_5	378806.STAUR_5471	5.746e-39	161.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,437ZV@68525|delta/epsilon subdivisions,2X39S@28221|Deltaproteobacteria,2YYEI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158456_k127_668465_0	1144275.COCOR_05606	3.205e-95	320.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YXCF@29|Myxococcales	28221|Deltaproteobacteria	S	MCM2/3/5 family	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158456_k127_67105_6	1382356.JQMP01000003_gene1987	3.672e-29	135.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158456_k127_67105_2	215803.DB30_4353	1.044e-160	516.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158456_k127_67105_1	861299.J421_6223	1.311e-164	562.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_67105_0	215803.DB30_4795	3.2e-260	823.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIWN@28221|Deltaproteobacteria,2Z2YC@29|Myxococcales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158456_k127_67105_3	68170.KL590481_gene1373	3.591e-77	290.0	COG1100@1|root,COG1262@1|root,COG2319@1|root,COG5635@1|root,COG1100@2|Bacteria,COG1262@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,2IB8E@201174|Actinobacteria,4DZBT@85010|Pseudonocardiales	201174|Actinobacteria	T	Small GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
SRR25158456_k127_67105_5	1356852.N008_00360	1.045e-53	195.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
SRR25158456_k127_67105_7	333138.LQ50_10315	1.046e-05	56.0	COG1266@1|root,COG1266@2|Bacteria,1V4WK@1239|Firmicutes,4HHKM@91061|Bacilli,1ZEBP@1386|Bacillus	91061|Bacilli	S	metal-dependent membrane protease	ypbD	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158456_k127_677147_0	1267535.KB906767_gene1458	4.237e-184	596.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria,2JIAM@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158456_k127_677147_4	926561.KB900617_gene1644	5.738e-26	123.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,3WBYJ@53433|Halanaerobiales	186801|Clostridia	G	PFAM Phosphoglycerate mutase	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158456_k127_677147_1	1158318.ATXC01000001_gene27	8.371e-161	524.0	COG0696@1|root,COG0696@2|Bacteria	2|Bacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158456_k127_677147_6	649349.Lbys_2700	2.515e-05	51.0	2C95S@1|root,335BQ@2|Bacteria,4NVV0@976|Bacteroidetes,47RV0@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158456_k127_677147_5	1007103.AFHW01000031_gene2305	9.737e-18	98.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,26SCR@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	ugpQ_2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158456_k127_677147_3	404589.Anae109_1476	3.947e-37	159.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158456_k127_677147_2	530564.Psta_4139	4.008e-60	213.0	COG2096@1|root,COG2096@2|Bacteria,2IZZ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158456_k127_682261_3	401053.AciPR4_3595	4.94e-130	423.0	COG0535@1|root,COG0535@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158456_k127_682261_0	1242864.D187_008204	0.0	1034.0	2C4IS@1|root,2Z81U@2|Bacteria,1MWZ8@1224|Proteobacteria	1224|Proteobacteria	S	Lantibiotic biosynthesis dehydratase C-term	-	-	-	ko:K20483	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	Lant_dehydr_C,Lant_dehydr_N
SRR25158456_k127_682261_1	378806.STAUR_3272	2.616e-243	775.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJEY@28221|Deltaproteobacteria,2YUDX@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158456_k127_682261_5	502025.Hoch_5838	6.01e-82	297.0	COG0845@1|root,COG0845@2|Bacteria,1Q2C6@1224|Proteobacteria,437YK@68525|delta/epsilon subdivisions,2X38G@28221|Deltaproteobacteria,2YUTX@29|Myxococcales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158456_k127_682261_11	330214.NIDE3917	8.288e-14	82.0	COG0845@1|root,COG0845@2|Bacteria,3J13X@40117|Nitrospirae	40117|Nitrospirae	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158456_k127_682261_4	1242864.D187_010239	2.002e-88	320.0	COG4403@1|root,COG4403@2|Bacteria,1R8AJ@1224|Proteobacteria,43EZ6@68525|delta/epsilon subdivisions,2WYJK@28221|Deltaproteobacteria,2YZ2R@29|Myxococcales	28221|Deltaproteobacteria	V	Lanthionine synthetase C-like protein	-	-	-	ko:K20484	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	LANC_like
SRR25158456_k127_682261_7	1453501.JELR01000002_gene875	9.762e-48	180.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,465VY@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
SRR25158456_k127_682261_9	1123253.AUBD01000002_gene1174	5.17e-20	106.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X40R@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SRR25158456_k127_682261_6	172088.AUGA01000003_gene5534	1.418e-50	183.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,2UA4V@28211|Alphaproteobacteria,3JZ1P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158456_k127_682261_13	1133849.O3I_028680	4.196e-06	52.0	COG3268@1|root,COG3268@2|Bacteria,2GMKU@201174|Actinobacteria,4FZHR@85025|Nocardiaceae	201174|Actinobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158456_k127_682261_10	67281.JNZZ01000016_gene6109	1.635e-17	85.0	COG3268@1|root,COG3268@2|Bacteria,2GMKU@201174|Actinobacteria,41CDZ@629295|Streptomyces griseus group	201174|Actinobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158456_k127_682261_2	306281.AJLK01000118_gene4092	2.661e-166	552.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158456_k127_682261_12	570952.ATVH01000014_gene2064	1.971e-13	83.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2UHJU@28211|Alphaproteobacteria,2JZTD@204441|Rhodospirillales	204441|Rhodospirillales	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158456_k127_682261_8	449447.MAE_37310	2.786e-24	118.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Peptidase_C14,Pkinase,TIR_2
SRR25158456_k127_684812_4	300852.55771702	1.509e-72	255.0	COG0223@1|root,COG0223@2|Bacteria,1WI0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158456_k127_684812_7	401053.AciPR4_0603	7.15e-50	194.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,3Y2NW@57723|Acidobacteria,2JHNM@204432|Acidobacteriia	204432|Acidobacteriia	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158456_k127_684812_9	1291050.JAGE01000001_gene655	4.939e-21	96.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3WKJ9@541000|Ruminococcaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158456_k127_684812_0	944479.JQLX01000001_gene1219	4.842e-113	376.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2WKZB@28221|Deltaproteobacteria,2M6WN@213113|Desulfurellales	28221|Deltaproteobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158456_k127_684812_1	234267.Acid_1799	1.779e-93	331.0	COG0384@1|root,COG0384@2|Bacteria,3Y7JN@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158456_k127_684812_8	349521.HCH_01090	1.862e-41	163.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,1XIB8@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
SRR25158456_k127_684812_6	1382306.JNIM01000001_gene289	1.668e-50	188.0	COG1028@1|root,COG1028@2|Bacteria	1382306.JNIM01000001_gene289|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_684812_2	867903.ThesuDRAFT_02308	3.404e-85	296.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WCG8@538999|Clostridiales incertae sedis	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158456_k127_684812_3	570967.JMLV01000003_gene2253	2.55e-75	261.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2JPB2@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158456_k127_684812_5	56780.SYN_00410	1.146e-71	260.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQE7@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158456_k127_685404_7	28072.Nos7524_1840	6.295e-51	184.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1G2E2@1117|Cyanobacteria,1HINK@1161|Nostocales	1117|Cyanobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158456_k127_685404_4	448385.sce6780	3.837e-65	228.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_685404_6	640510.BC1001_5000	2.198e-58	215.0	COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,2VMWD@28216|Betaproteobacteria,1K188@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158456_k127_685404_3	1120972.AUMH01000019_gene2331	3.835e-70	253.0	COG0535@1|root,COG0535@2|Bacteria,1V3RE@1239|Firmicutes,4HST7@91061|Bacilli	91061|Bacilli	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158456_k127_685404_10	1202768.JROF01000007_gene2664	2.317e-11	67.0	COG0298@1|root,arCOG04427@2157|Archaea,2Y6YP@28890|Euryarchaeota,23XNM@183963|Halobacteria	183963|Halobacteria	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158456_k127_685404_9	438753.AZC_0071	3.399e-18	97.0	COG2516@1|root,COG2516@2|Bacteria,1MWZQ@1224|Proteobacteria,2TV9Z@28211|Alphaproteobacteria,3EYNX@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158456_k127_685404_1	867903.ThesuDRAFT_00352	6.406e-239	775.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
SRR25158456_k127_685404_0	204669.Acid345_0364	0.0	1020.0	COG3256@1|root,COG3256@2|Bacteria,3Y2GQ@57723|Acidobacteria,2JKWD@204432|Acidobacteriia	204432|Acidobacteriia	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SRR25158456_k127_685404_8	1122223.KB890701_gene2296	2.196e-36	160.0	294HY@1|root,2ZRXK@2|Bacteria,1WK25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
SRR25158456_k127_685404_2	1041159.AZUW01000062_gene3637	3.752e-184	597.0	COG1404@1|root,COG1404@2|Bacteria,1PSEZ@1224|Proteobacteria,2V4M5@28211|Alphaproteobacteria,4BFDK@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158456_k127_685404_5	936136.ARRT01000007_gene1060	3.404e-61	232.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,2U7SC@28211|Alphaproteobacteria,4BI87@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158456_k127_685404_11	231434.JQJH01000017_gene1249	7.072e-11	65.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,2UKC0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_685464_4	266835.14026225	3.044e-68	233.0	2DMQT@1|root,32T2H@2|Bacteria,1N1B2@1224|Proteobacteria,2UDE4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR25158456_k127_685464_8	266835.14026224	1.654e-25	112.0	arCOG11411@1|root,33A8Q@2|Bacteria,1NKM4@1224|Proteobacteria,2UNC1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_685464_6	266835.14026223	2.876e-45	167.0	arCOG11412@1|root,31S84@2|Bacteria,1N14M@1224|Proteobacteria,2UDB1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_685464_3	1198452.Jab_2c07030	1.109e-68	236.0	2DB76@1|root,2Z7JZ@2|Bacteria,1R41X@1224|Proteobacteria,2VMX8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
SRR25158456_k127_685464_0	266835.14026221	1.805e-249	778.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,2TVB3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Cadherin_3,Phage_sheath_1,Phage_sheath_1C
SRR25158456_k127_685464_2	266835.14026220	4.822e-97	329.0	2EZGM@1|root,33SMS@2|Bacteria,1NTTJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_685464_7	266835.14026219	3.377e-39	162.0	2F7NF@1|root,3402X@2|Bacteria,1NYWH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_685464_5	266835.14026218	8.721e-62	233.0	arCOG11409@1|root,2ZYEP@2|Bacteria,1Q8VD@1224|Proteobacteria,2UYY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
SRR25158456_k127_685464_1	266835.14026217	5.145e-214	692.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,2TU3E@28211|Alphaproteobacteria,43Q3R@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
SRR25158456_k127_685464_9	1117315.AHCA01000015_gene1704	1.751e-14	86.0	2D62R@1|root,32TKD@2|Bacteria,1MZY7@1224|Proteobacteria,1SR23@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158456_k127_689261_1	1379698.RBG1_1C00001G0508	1.971e-143	464.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	bktB	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158456_k127_689261_7	1122176.KB903576_gene4915	3.419e-24	115.0	COG1266@1|root,COG1266@2|Bacteria,4NHRW@976|Bacteroidetes,1IYXV@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158456_k127_689261_12	709986.Deima_0322	3.945e-09	69.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	catD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158456_k127_689261_11	404589.Anae109_0288	7.379e-18	89.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158456_k127_689261_6	856793.MICA_1184	1.486e-26	114.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,4BQKE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
SRR25158456_k127_689261_3	234267.Acid_1281	3.461e-48	180.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
SRR25158456_k127_689261_8	204669.Acid345_1862	1.117e-19	98.0	COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SRR25158456_k127_689261_10	204669.Acid345_0152	4.156e-18	94.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria,2JISD@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SRR25158456_k127_689261_4	1444309.JAQG01000005_gene4332	3.052e-46	176.0	COG3483@1|root,COG3483@2|Bacteria,1VTTH@1239|Firmicutes,4HU1U@91061|Bacilli	91061|Bacilli	E	Tryptophan 2,3-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_dioxygenase
SRR25158456_k127_689261_0	289376.THEYE_A0208	4.063e-167	535.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3J0E0@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158456_k127_689261_9	234267.Acid_1509	2.998e-18	99.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_689261_2	379066.GAU_0026	1.274e-76	274.0	COG1744@1|root,COG1744@2|Bacteria,1ZSMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158456_k127_689261_5	1242864.D187_006522	1.236e-38	150.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,42NTY@68525|delta/epsilon subdivisions,2WK4F@28221|Deltaproteobacteria,2YUKQ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158456_k127_693190_4	29581.BW37_04183	2.135e-16	85.0	2C7KZ@1|root,32RJE@2|Bacteria,1N3NH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_693190_3	102129.Lepto7375DRAFT_3753	5.401e-201	661.0	28H5N@1|root,2Z7I8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_693190_0	272134.KB731324_gene1542	0.0	1467.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF4349,Flg_new,HWE_HK,Methyltransf_21,PAS_10,SBP_bac_5
SRR25158456_k127_693190_1	272134.KB731324_gene1543	0.0	1187.0	COG0222@1|root,COG0222@2|Bacteria,1GBZT@1117|Cyanobacteria,1HEC7@1150|Oscillatoriales	1117|Cyanobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_693190_2	272134.KB731324_gene1544	2.048e-284	905.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	AAA_13,AAA_23,Kelch_1,Kelch_4,Peptidase_C14,Tubulin_2,WD40
SRR25158456_k127_695844_2	1123261.AXDW01000007_gene2160	1.615e-100	342.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1X41T@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	styS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
SRR25158456_k127_695844_0	1129374.AJE_12139	1.184e-138	454.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,465Q7@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_695844_6	1120953.AUBH01000001_gene914	6.853e-59	220.0	COG0577@1|root,COG0577@2|Bacteria,1MXFC@1224|Proteobacteria,1RQX0@1236|Gammaproteobacteria,46698@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_695844_1	493475.GARC_3472	1.423e-103	363.0	COG0577@1|root,COG0577@2|Bacteria,1QSVW@1224|Proteobacteria,1RPBM@1236|Gammaproteobacteria,465M6@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_695844_3	1453501.JELR01000001_gene3146	2.334e-100	332.0	COG1136@1|root,COG1136@2|Bacteria,1NHCD@1224|Proteobacteria,1RNIX@1236|Gammaproteobacteria,464FN@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC transporter	ycfV	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_695844_4	1384056.N787_10630	1.786e-90	312.0	COG0845@1|root,COG0845@2|Bacteria,1NQDN@1224|Proteobacteria,1RRFE@1236|Gammaproteobacteria,1X3QX@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	ybjY	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158456_k127_695844_9	1294265.JCM21738_575	0.0009819	49.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
SRR25158456_k127_695844_5	1110502.TMO_0241	4.887e-76	260.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,2JSHV@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158456_k127_695844_8	1283300.ATXB01000001_gene1254	1.759e-18	93.0	COG1598@1|root,COG1598@2|Bacteria,1NMQ9@1224|Proteobacteria,1SJ5A@1236|Gammaproteobacteria,1XFVK@135618|Methylococcales	135618|Methylococcales	S	PFAM Uncharacterised protein family (UPF0150)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_709026_5	378806.STAUR_0621	1.707e-16	84.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2YVU0@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
SRR25158456_k127_709026_6	313624.NSP_39550	4.167e-14	81.0	COG2062@1|root,COG2062@2|Bacteria,1G6QD@1117|Cyanobacteria,1HN53@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM Phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158456_k127_709026_1	1519464.HY22_08585	1.951e-96	335.0	COG0248@1|root,COG0248@2|Bacteria,1FDDR@1090|Chlorobi	1090|Chlorobi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158456_k127_709026_0	1131812.JQMS01000001_gene1237	1.766e-98	331.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,1I2BC@117743|Flavobacteriia,2NTPT@237|Flavobacterium	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158456_k127_709026_4	517418.Ctha_0896	4.67e-46	182.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	oprP	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SRR25158456_k127_709026_3	1382306.JNIM01000001_gene1232	8.135e-57	227.0	COG5002@1|root,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
SRR25158456_k127_709026_2	1499967.BAYZ01000182_gene4450	5.998e-67	233.0	COG1694@1|root,COG3956@2|Bacteria,2NP9V@2323|unclassified Bacteria	2|Bacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG
SRR25158456_k127_715403_1	983545.Glaag_1898	5.933e-119	403.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158456_k127_715403_0	661478.OP10G_2255	1.917e-157	507.0	COG2252@1|root,COG2252@2|Bacteria	2|Bacteria	S	purine nucleobase transmembrane transporter activity	yicO	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158456_k127_716255_2	471854.Dfer_1756	1.693e-78	266.0	COG1749@1|root,COG3386@1|root,COG1749@2|Bacteria,COG3386@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
SRR25158456_k127_716255_0	1173025.GEI7407_2976	3.083e-193	627.0	COG0021@1|root,COG0021@2|Bacteria,1G0GC@1117|Cyanobacteria,1H7T2@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158456_k127_716255_3	1242864.D187_003993	3.465e-08	63.0	2ESNI@1|root,33K73@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
SRR25158456_k127_716255_1	1218075.BAYA01000049_gene6763	4.125e-95	320.0	COG1366@1|root,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria,2VNVR@28216|Betaproteobacteria,1K26J@119060|Burkholderiaceae	28216|Betaproteobacteria	T	RsbT co-antagonist protein rsbRD N-terminal domain	rsbRA	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,RsbRD_N,STAS
SRR25158456_k127_721203_2	43151.ADAC009206-PA	0.0003527	54.0	KOG0613@1|root,KOG4475@1|root,KOG0613@2759|Eukaryota,KOG4475@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,41WSG@6656|Arthropoda,3SJC8@50557|Insecta,4522N@7147|Diptera,45HQK@7148|Nematocera	33208|Metazoa	T	Immunoglobulin like	unc-22	GO:0003008,GO:0003012,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005859,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006996,GO:0007010,GO:0007015,GO:0007498,GO:0007610,GO:0007626,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0008344,GO:0009636,GO:0009653,GO:0009888,GO:0009987,GO:0010638,GO:0010720,GO:0010927,GO:0015629,GO:0016043,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022603,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030534,GO:0031032,GO:0031033,GO:0031034,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032956,GO:0032970,GO:0032989,GO:0032991,GO:0033043,GO:0034622,GO:0035094,GO:0035095,GO:0036211,GO:0040012,GO:0040017,GO:0042221,GO:0042493,GO:0042692,GO:0042805,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0043933,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045214,GO:0045595,GO:0045597,GO:0045933,GO:0045989,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051015,GO:0051094,GO:0051128,GO:0051130,GO:0051146,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051239,GO:0051240,GO:0051302,GO:0051371,GO:0051393,GO:0051493,GO:0051495,GO:0051782,GO:0055001,GO:0055002,GO:0060284,GO:0060297,GO:0060298,GO:0061061,GO:0065003,GO:0065007,GO:0070925,GO:0071688,GO:0071689,GO:0071704,GO:0071840,GO:0090257,GO:0097435,GO:0097493,GO:0099080,GO:0099081,GO:0099512,GO:0110020,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1902903,GO:1902905	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_3,Pkinase,fn3
SRR25158456_k127_721203_1	215803.DB30_4889	9.738e-09	69.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cadherin_3,Calx-beta,DUF4214,DUF4347,He_PIG
SRR25158456_k127_721203_0	316274.Haur_2567	1.254e-103	354.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,376E3@32061|Chloroflexia	32061|Chloroflexia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158456_k127_727262_0	290397.Adeh_1631	1.823e-81	283.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YURZ@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158456_k127_727262_3	1340493.JNIF01000003_gene2471	3.016e-10	65.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_727262_2	1123405.AUMM01000034_gene1692	1.624e-34	143.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
SRR25158456_k127_727262_1	63737.Npun_R0269	5.33e-38	146.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	CHRD,DUF839,HemolysinCabind,Phytase-like
SRR25158456_k127_733656_1	497964.CfE428DRAFT_1182	1.251e-110	372.0	COG0300@1|root,COG0300@2|Bacteria,46TCZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158456_k127_733656_0	1185652.USDA257_c04170	9.423e-238	753.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria,4B9N1@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158456_k127_733656_3	448385.sce0162	7.899e-38	157.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158456_k127_733656_2	861299.J421_1003	4.069e-102	352.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158456_k127_733656_4	1219035.NT2_02_04420	3.274e-21	106.0	2EA9M@1|root,334E1@2|Bacteria,1ND0N@1224|Proteobacteria	1224|Proteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158456_k127_736892_0	1121013.P873_08135	2.714e-275	863.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,1X50C@135614|Xanthomonadales	135614|Xanthomonadales	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
SRR25158456_k127_736892_8	375286.mma_3041	2.255e-19	98.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,4733E@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158456_k127_736892_7	870187.Thini_1533	1.13e-19	99.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,Peptidase_S74
SRR25158456_k127_736892_1	234267.Acid_3288	6.894e-90	298.0	COG3865@1|root,COG3865@2|Bacteria,3Y4UB@57723|Acidobacteria	57723|Acidobacteria	H	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
SRR25158456_k127_736892_6	1320556.AVBP01000007_gene620	8.971e-22	99.0	COG5580@1|root,COG5580@2|Bacteria	2|Bacteria	O	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_736892_4	378806.STAUR_4199	3.024e-48	193.0	28M9U@1|root,2ZANN@2|Bacteria,1NXC3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_736892_3	1142394.PSMK_09620	1.035e-54	218.0	COG1028@1|root,COG1028@2|Bacteria,2J42Z@203682|Planctomycetes	203682|Planctomycetes	IQ	Short-chain dehydrogenase reductase Sdr	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_736892_2	176946.XP_007437356.1	1.125e-77	268.0	COG0434@1|root,2QUBS@2759|Eukaryota,38EZC@33154|Opisthokonta,3BES3@33208|Metazoa,3D0S4@33213|Bilateria,47ZQG@7711|Chordata,4905V@7742|Vertebrata	33208|Metazoa	S	protein F13E9.13, mitochondrial-like	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
SRR25158456_k127_736892_9	795666.MW7_1546	3.791e-12	76.0	COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1N8AF@1224|Proteobacteria,2VVF1@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
SRR25158456_k127_736892_5	134676.ACPL_3232	1.805e-23	104.0	2DC71@1|root,32TZ3@2|Bacteria,2H338@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_737307_1	204669.Acid345_2047	3.372e-104	366.0	COG0577@1|root,COG0577@2|Bacteria,3Y6R1@57723|Acidobacteria,2JMKX@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_737307_5	765420.OSCT_2180	9.539e-31	137.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2G7M2@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
SRR25158456_k127_737307_2	1237149.C900_05622	1.725e-66	236.0	COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia	976|Bacteroidetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158456_k127_737307_4	1301098.PKB_3112	3.711e-39	153.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,1SABZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	enzyme involved in biosynthesis of extracellular polysaccharides	yqjZ	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158456_k127_737307_0	926549.KI421517_gene3934	5.168e-303	947.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SRR25158456_k127_737307_3	1242864.D187_004594	1.138e-48	179.0	28YTJ@1|root,2ZKKT@2|Bacteria,1RBH7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_737403_0	1304865.JAGF01000001_gene234	8.464e-100	331.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria	201174|Actinobacteria	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158456_k127_737403_1	1183377.Py04_1357	9.442e-55	210.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,243JH@183968|Thermococci	183968|Thermococci	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158456_k127_737403_2	1128421.JAGA01000003_gene3091	2.333e-05	58.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
SRR25158456_k127_73899_1	945713.IALB_0783	3.16e-261	814.0	COG2987@1|root,COG2987@2|Bacteria	2|Bacteria	E	urocanate hydratase activity	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_0688	Urocanase,Urocanase_C,Urocanase_N
SRR25158456_k127_73899_9	1190603.AJYD01000023_gene699	9.209e-75	282.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1XSEJ@135623|Vibrionales	135623|Vibrionales	I	desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158456_k127_73899_7	204669.Acid345_1052	5.043e-94	339.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
SRR25158456_k127_73899_19	500633.CLOHIR_00271	1.997e-13	81.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25SC0@186804|Peptostreptococcaceae	186801|Clostridia	O	peptidyl-prolyl isomerase	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
SRR25158456_k127_73899_20	1288494.EBAPG3_24180	2.152e-11	75.0	29WWS@1|root,30IIN@2|Bacteria,1Q0FD@1224|Proteobacteria,2W6Q0@28216|Betaproteobacteria,374F9@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
SRR25158456_k127_73899_23	394503.Ccel_0074	4.049e-05	56.0	2DP71@1|root,330U0@2|Bacteria,1VD7T@1239|Firmicutes,24R5M@186801|Clostridia,36P3M@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
SRR25158456_k127_73899_6	1304880.JAGB01000002_gene2311	1.437e-122	409.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158456_k127_73899_14	338963.Pcar_1476	2.114e-40	167.0	28N9P@1|root,2ZBDN@2|Bacteria,1R70P@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
SRR25158456_k127_73899_5	204669.Acid345_2529	6.415e-140	456.0	COG1030@1|root,COG1030@2|Bacteria,3Y31N@57723|Acidobacteria,2JHS7@204432|Acidobacteriia	204432|Acidobacteriia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158456_k127_73899_21	330214.NIDE3027	2.147e-10	65.0	COG0463@1|root,COG0463@2|Bacteria,3J0M5@40117|Nitrospirae	40117|Nitrospirae	M	biosynthesis glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158456_k127_73899_16	1122226.AUHX01000005_gene2439	1.876e-36	145.0	COG1216@1|root,COG1216@2|Bacteria,4PKBZ@976|Bacteroidetes,1IJBV@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
SRR25158456_k127_73899_17	1382356.JQMP01000004_gene531	1.362e-35	157.0	COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia	189775|Thermomicrobia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_73899_4	204669.Acid345_3211	6.305e-167	548.0	COG1228@1|root,COG1228@2|Bacteria,3Y32S@57723|Acidobacteria,2JIA1@204432|Acidobacteriia	2|Bacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158456_k127_73899_12	1201288.M900_A0272	1.458e-45	175.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
SRR25158456_k127_73899_0	404589.Anae109_1724	0.0	1788.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YU11@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158456_k127_73899_8	404589.Anae109_1725	1.209e-84	292.0	COG0266@1|root,COG0266@2|Bacteria,1N1J5@1224|Proteobacteria,433TA@68525|delta/epsilon subdivisions,2X3D6@28221|Deltaproteobacteria,2YVHV@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158456_k127_73899_24	1146883.BLASA_2162	8.049e-05	53.0	COG3654@1|root,COG3654@2|Bacteria,2IR34@201174|Actinobacteria,4ET91@85013|Frankiales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158456_k127_73899_3	1385519.N801_16315	3.528e-168	539.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4FE8B@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158456_k127_73899_22	1121374.KB891575_gene932	3.136e-08	61.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	rhodanese-related sulfurtransferase	yibN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158456_k127_73899_10	1499967.BAYZ01000095_gene4228	9.82e-75	257.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158456_k127_73899_2	204669.Acid345_1402	5.346e-195	619.0	COG2268@1|root,COG2268@2|Bacteria,3Y3UJ@57723|Acidobacteria,2JHYB@204432|Acidobacteriia	204432|Acidobacteriia	S	Flotillin	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
SRR25158456_k127_73899_18	234267.Acid_4572	1.937e-32	132.0	COG1585@1|root,COG1585@2|Bacteria,3Y4Y0@57723|Acidobacteria	57723|Acidobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_73899_13	204669.Acid345_1399	5.833e-45	169.0	COG1396@1|root,COG1396@2|Bacteria,3Y4K9@57723|Acidobacteria,2JMP4@204432|Acidobacteriia	204432|Acidobacteriia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_73899_11	234267.Acid_6601	1.107e-53	216.0	COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,RibD_C,SpoIIE
SRR25158456_k127_73899_15	102129.Lepto7375DRAFT_4605	1.914e-37	149.0	COG0302@1|root,COG0302@2|Bacteria,1G1K8@1117|Cyanobacteria,1HF5A@1150|Oscillatoriales	1117|Cyanobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.folE,iJN678.folE	GTP_cyclohydroI
SRR25158456_k127_744572_17	398578.Daci_2799	4.825e-14	76.0	2DNYG@1|root,32ZSX@2|Bacteria,1NDAI@1224|Proteobacteria,2VWNW@28216|Betaproteobacteria,4AIUB@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_744572_16	497321.C664_18764	6.979e-17	89.0	COG1848@1|root,COG1848@2|Bacteria,1MZCP@1224|Proteobacteria,2VUKN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_744572_13	290397.Adeh_0477	4.7e-29	135.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
SRR25158456_k127_744572_0	234267.Acid_6926	3.874e-264	823.0	COG0374@1|root,COG0374@2|Bacteria,3Y3C2@57723|Acidobacteria	57723|Acidobacteria	C	nickel-dependent hydrogenase, large subunit	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SRR25158456_k127_744572_5	234267.Acid_6925	1.095e-94	327.0	COG5557@1|root,COG5557@2|Bacteria,3Y6AT@57723|Acidobacteria	57723|Acidobacteria	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_744572_6	234267.Acid_6924	8.843e-91	323.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	hybA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0006066,GO:0006071,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016052,GO:0019400,GO:0019405,GO:0019563,GO:0019588,GO:0019662,GO:0019751,GO:0031224,GO:0031226,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:0071944,GO:1901575,GO:1901615,GO:1901616	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7,TAT_signal
SRR25158456_k127_744572_3	204669.Acid345_4237	2.43e-148	479.0	COG1740@1|root,COG1740@2|Bacteria,3Y3HS@57723|Acidobacteria,2JJYD@204432|Acidobacteriia	204432|Acidobacteriia	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
SRR25158456_k127_744572_20	1242864.D187_009981	0.0001612	53.0	COG0457@1|root,COG0457@2|Bacteria	1242864.D187_009981|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_744572_14	246197.MXAN_3254	1.567e-27	127.0	COG2332@1|root,COG2332@2|Bacteria,1PZFU@1224|Proteobacteria,42U7H@68525|delta/epsilon subdivisions,2WQ19@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158456_k127_744572_7	670487.Ocepr_1224	9.349e-78	278.0	COG1013@1|root,COG1013@2|Bacteria,1WIGM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158456_k127_744572_2	670487.Ocepr_1225	4.789e-157	516.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1WIAF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
SRR25158456_k127_744572_1	404589.Anae109_2250	9.043e-166	545.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRR25158456_k127_744572_8	204669.Acid345_1498	1.071e-77	266.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158456_k127_744572_11	671143.DAMO_2768	1.12e-32	134.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158456_k127_744572_18	1463861.JNXE01000016_gene7280	1.13e-11	68.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158456_k127_744572_12	880073.Calab_2517	4.595e-29	121.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158456_k127_744572_10	331869.BAL199_24289	1.669e-40	156.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VC8M@28211|Alphaproteobacteria,4BSKF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_744572_4	1278073.MYSTI_00257	1.912e-119	402.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1MVGV@1224|Proteobacteria,42WJ6@68525|delta/epsilon subdivisions,2WQ9K@28221|Deltaproteobacteria,2YXTM@29|Myxococcales	28221|Deltaproteobacteria	PT	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158456_k127_744572_9	765910.MARPU_14415	2.741e-42	164.0	COG0457@1|root,COG0457@2|Bacteria,1N4EF@1224|Proteobacteria,1SRCF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_744572_15	448385.sce5624	6.792e-22	97.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,439C3@68525|delta/epsilon subdivisions,2X4K7@28221|Deltaproteobacteria,2YZ6K@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158456_k127_747188_2	1449336.JQLO01000001_gene2269	2.492e-86	293.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,27FWN@186828|Carnobacteriaceae	91061|Bacilli	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158456_k127_747188_5	861299.J421_2559	3.489e-62	223.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158456_k127_747188_11	316274.Haur_0845	7.181e-28	127.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SRR25158456_k127_747188_1	401053.AciPR4_3006	5.855e-94	347.0	COG1104@1|root,COG1104@2|Bacteria,3Y389@57723|Acidobacteria,2JIPA@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158456_k127_747188_14	1047013.AQSP01000131_gene1842	3.733e-13	84.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,Dynamin_N,Peptidase_M48,TPR_19,TPR_8
SRR25158456_k127_747188_10	204669.Acid345_2506	3.806e-30	140.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158456_k127_747188_12	1047013.AQSP01000088_gene1632	1.86e-17	98.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2NR7I@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	BatD,TPR_16,TPR_2,TPR_6,TPR_8
SRR25158456_k127_747188_9	234267.Acid_6308	3.18e-30	139.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158456_k127_747188_8	1121127.JAFA01000022_gene7830	7.73e-40	160.0	COG4271@1|root,COG4271@2|Bacteria,1RHKG@1224|Proteobacteria,2VVAD@28216|Betaproteobacteria,1KAX0@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Predicted nucleotide-binding protein containing TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR-like
SRR25158456_k127_747188_4	693977.Deipr_1828	3.496e-68	246.0	COG1760@1|root,COG1760@2|Bacteria,1WI9G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	TIGRFAM L-serine dehydratase, iron-sulfur-dependent, alpha subunit	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
SRR25158456_k127_747188_6	649638.Trad_2756	4.869e-60	214.0	COG1760@1|root,COG1760@2|Bacteria,1WIC1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	TIGRFAM L-serine dehydratase, iron-sulfur-dependent, beta subunit	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
SRR25158456_k127_747188_13	1280946.HY29_04050	8.214e-16	91.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2UA4W@28211|Alphaproteobacteria,4405V@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	2.7.13.3	ko:K03407,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	Hpt,Response_reg
SRR25158456_k127_747188_0	1158338.JNLJ01000001_gene789	1.05e-144	471.0	COG0191@1|root,COG0191@2|Bacteria,2G3VP@200783|Aquificae	200783|Aquificae	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158456_k127_747188_3	861299.J421_0742	4.111e-86	297.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158456_k127_747188_7	1449069.JMLO01000006_gene1051	4.747e-47	172.0	2DFAP@1|root,2ZR44@2|Bacteria,2H7P6@201174|Actinobacteria,4G3B2@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158456_k127_748467_2	1237149.C900_00291	8.872e-45	166.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158456_k127_748467_3	195253.Syn6312_2999	3.762e-23	102.0	COG1669@1|root,COG1669@2|Bacteria,1G889@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158456_k127_748467_5	1148.1652631	8.79e-05	45.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1H67F@1142|Synechocystis	1117|Cyanobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158456_k127_748467_1	1096546.WYO_3579	1.853e-78	266.0	COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,2U5F8@28211|Alphaproteobacteria,1JUIR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM transferase hexapeptide repeat containing protein	nodL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008374,GO:0008925,GO:0009987,GO:0016043,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
SRR25158456_k127_748467_4	1262915.BN574_00519	1.272e-09	67.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	DUF1956,TetR_N
SRR25158456_k127_748467_0	666685.R2APBS1_2201	1.992e-88	329.0	COG1404@1|root,COG3509@1|root,COG4733@1|root,COG1404@2|Bacteria,COG3509@2|Bacteria,COG4733@2|Bacteria,1R1F7@1224|Proteobacteria,1T50E@1236|Gammaproteobacteria,1X534@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_753932_2	562970.Btus_1051	1.188e-71	246.0	COG1028@1|root,COG1028@2|Bacteria,1TPDB@1239|Firmicutes,4HAKR@91061|Bacilli,2792M@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158456_k127_753932_0	1519464.HY22_06470	1.141e-167	537.0	COG1473@1|root,COG1473@2|Bacteria,1FDR4@1090|Chlorobi	2|Bacteria	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158456_k127_753932_1	493475.GARC_2930	7.458e-93	327.0	COG1228@1|root,COG1228@2|Bacteria,1RCA0@1224|Proteobacteria,1S08B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CIA30
SRR25158456_k127_753932_3	1182590.BN5_03942	4.375e-29	124.0	COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,1S7Z5@1236|Gammaproteobacteria,1YJ27@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158456_k127_761797_2	1267535.KB906767_gene3255	1.252e-79	272.0	COG2041@1|root,COG2041@2|Bacteria,3Y6BS@57723|Acidobacteria,2JKPT@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158456_k127_761797_1	1166018.FAES_3780	1.187e-86	295.0	COG4117@1|root,COG4117@2|Bacteria,4NG6M@976|Bacteroidetes,47NBT@768503|Cytophagia	976|Bacteroidetes	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
SRR25158456_k127_761797_3	246197.MXAN_3119	6.835e-73	258.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,42P6V@68525|delta/epsilon subdivisions,2WM6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
SRR25158456_k127_761797_4	1133849.O3I_007565	3.73e-39	169.0	COG1413@1|root,COG1413@2|Bacteria,2IC1N@201174|Actinobacteria,4FYUP@85025|Nocardiaceae	201174|Actinobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SRR25158456_k127_761797_0	1163408.UU9_02399	1.271e-110	392.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,1XCVX@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158456_k127_76343_1	1341646.CBMO010000122_gene2033	9.616e-14	85.0	COG0438@1|root,COG0438@2|Bacteria,2IA7N@201174|Actinobacteria,23D5C@1762|Mycobacteriaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_76343_0	880073.Calab_2316	3.504e-51	199.0	COG0726@1|root,COG0726@2|Bacteria,2NRRE@2323|unclassified Bacteria	2|Bacteria	G	polysaccharide deacetylase	walW	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_76343_2	671143.DAMO_0253	3.282e-12	73.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
SRR25158456_k127_770247_0	84531.JMTZ01000038_gene3624	1.866e-59	237.0	COG3562@1|root,COG3562@2|Bacteria,1QC30@1224|Proteobacteria,1T7R1@1236|Gammaproteobacteria,1X9KH@135614|Xanthomonadales	135614|Xanthomonadales	M	Capsule polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Capsule_synth
SRR25158456_k127_770247_3	196367.JNFG01000200_gene3087	2.773e-13	85.0	COG0438@1|root,COG0438@2|Bacteria,1QUN0@1224|Proteobacteria,2W5SP@28216|Betaproteobacteria,1K3FE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_770247_2	292564.Cyagr_1204	2.336e-14	89.0	COG1216@1|root,COG1216@2|Bacteria,1GIVG@1117|Cyanobacteria,22THI@167375|Cyanobium	1117|Cyanobacteria	S	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158456_k127_770247_4	324602.Caur_1741	6.772e-11	77.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_1,Glycos_transf_2
SRR25158456_k127_770247_1	429009.Adeg_1129	1.142e-34	156.0	COG0500@1|root,COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,COG2226@2|Bacteria,1V06G@1239|Firmicutes,247WU@186801|Clostridia,42H9R@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_23
SRR25158456_k127_774520_4	1163408.UU9_06464	5.429e-35	139.0	COG5592@1|root,COG5592@2|Bacteria,1ND3D@1224|Proteobacteria,1SJGE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hemerythrin hhe cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158456_k127_774520_1	861299.J421_2858	4.273e-85	295.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
SRR25158456_k127_774520_5	401053.AciPR4_3070	1.814e-19	102.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria,2JI8N@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SRR25158456_k127_774520_0	234267.Acid_5076	7.969e-133	430.0	COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria	57723|Acidobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158456_k127_774520_2	861299.J421_1851	2.496e-54	198.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	thiJ	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158456_k127_774520_3	452637.Oter_2363	2.707e-44	169.0	2CFSQ@1|root,32S2E@2|Bacteria,46VN9@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_775942_4	485913.Krac_8781	6.061e-52	198.0	COG0535@1|root,COG0535@2|Bacteria,2G7WG@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SRR25158456_k127_775942_3	641491.DND132_1483	5.563e-70	256.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158456_k127_775942_7	537971.HCCG_01507	1.25e-18	97.0	COG0535@1|root,COG0535@2|Bacteria,1Q4MU@1224|Proteobacteria,42U7S@68525|delta/epsilon subdivisions,2YRZI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
SRR25158456_k127_775942_6	1443665.JACA01000013_gene4117	5.98e-25	108.0	2AVBG@1|root,31M2S@2|Bacteria,4NQIJ@976|Bacteroidetes,1I3P4@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_775942_5	290397.Adeh_4303	2.175e-40	160.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,43DY0@68525|delta/epsilon subdivisions,2X918@28221|Deltaproteobacteria,2Z1ER@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158456_k127_775942_1	1382356.JQMP01000004_gene323	2.439e-88	302.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
SRR25158456_k127_775942_0	1267535.KB906767_gene2922	2.23e-125	410.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158456_k127_775942_2	1238182.C882_0401	9.989e-74	281.0	COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VFY5@28211|Alphaproteobacteria,2JRKP@204441|Rhodospirillales	204441|Rhodospirillales	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158456_k127_776838_9	1318628.MARLIPOL_10896	8.613e-05	54.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4667H@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,TPR_12,TPR_7,TPR_8
SRR25158456_k127_776838_5	357808.RoseRS_4252	1.222e-27	120.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM9_2,DUF362
SRR25158456_k127_776838_6	395495.Lcho_3739	4.251e-11	77.0	COG0689@1|root,COG5276@1|root,COG0689@2|Bacteria,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria	1224|Proteobacteria	N	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,He_PIG,LVIVD
SRR25158456_k127_776838_8	103690.17130047	3.848e-05	52.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1HJ6U@1161|Nostocales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158456_k127_776838_4	1267534.KB906755_gene4692	1.561e-43	177.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_776838_3	555088.DealDRAFT_2158	4.111e-50	186.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	yycF	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158456_k127_776838_0	697303.Thewi_1817	3.435e-105	355.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_776838_7	392500.Swoo_2343	2.141e-07	63.0	COG1748@1|root,COG1748@2|Bacteria,1P35E@1224|Proteobacteria,1RZB7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158456_k127_776838_2	215803.DB30_4074	1.574e-51	188.0	2DGKH@1|root,2ZWDA@2|Bacteria,1Q2F1@1224|Proteobacteria,4380V@68525|delta/epsilon subdivisions,2X3AV@28221|Deltaproteobacteria,2YV6E@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_776838_10	525904.Tter_0083	0.000377	53.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NACHT,SIR2_2,TPR_1,TPR_11,TPR_2,TPR_8
SRR25158456_k127_776838_1	234267.Acid_7868	5.87e-67	239.0	COG1230@1|root,COG1230@2|Bacteria,3Y32W@57723|Acidobacteria	57723|Acidobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158456_k127_77770_0	215803.DB30_4307	0.0	1333.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q2ZJ@1224|Proteobacteria,438P5@68525|delta/epsilon subdivisions,2X8TH@28221|Deltaproteobacteria,2YXE6@29|Myxococcales	28221|Deltaproteobacteria	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158456_k127_77770_1	1122223.KB890696_gene415	3.832e-59	213.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
SRR25158456_k127_77770_2	234267.Acid_2705	1.755e-15	89.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158456_k127_790546_16	1123366.TH3_02430	8.915e-12	74.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,2JZRZ@204441|Rhodospirillales	204441|Rhodospirillales	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
SRR25158456_k127_790546_13	1267535.KB906767_gene5467	4.444e-28	132.0	COG1403@1|root,COG1403@2|Bacteria,3Y500@57723|Acidobacteria	57723|Acidobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
SRR25158456_k127_790546_0	1411123.JQNH01000001_gene1754	1.614e-213	679.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2U3EK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Domain of unknown function (DUF3459)	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158456_k127_790546_7	290397.Adeh_0314	2.551e-66	235.0	COG0599@1|root,COG0599@2|Bacteria,1QTWT@1224|Proteobacteria,43CBT@68525|delta/epsilon subdivisions,2X7MK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	ahpD	-	-	ko:K04756	-	-	-	-	ko00000	-	-	-	CMD
SRR25158456_k127_790546_8	290397.Adeh_0313	9.522e-63	227.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WP90@28221|Deltaproteobacteria,2YVP3@29|Myxococcales	28221|Deltaproteobacteria	O	Alkyl hydroperoxide reductase	prx-1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158456_k127_790546_12	903818.KI912268_gene3050	1.538e-30	124.0	COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158456_k127_790546_11	861299.J421_1529	5.331e-33	139.0	COG1191@1|root,COG1191@2|Bacteria,1ZV0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	sigma factor activity	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	-
SRR25158456_k127_790546_19	234267.Acid_6859	9.197e-06	57.0	COG0457@1|root,COG4235@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4235@2|Bacteria,COG4995@2|Bacteria,3Y4TR@57723|Acidobacteria	57723|Acidobacteria	O	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_790546_15	1123279.ATUS01000005_gene3203	1.542e-21	111.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,1T462@1236|Gammaproteobacteria,1JAZP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158456_k127_790546_5	1382359.JIAL01000001_gene1325	1.547e-90	304.0	COG0600@1|root,COG0600@2|Bacteria,3Y5KR@57723|Acidobacteria,2JNDD@204432|Acidobacteriia	204432|Acidobacteriia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158456_k127_790546_3	1382359.JIAL01000001_gene1326	7.431e-112	367.0	COG1116@1|root,COG1116@2|Bacteria,3Y4J1@57723|Acidobacteria,2JMUR@204432|Acidobacteriia	204432|Acidobacteriia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158456_k127_790546_6	1382359.JIAL01000001_gene1327	5.086e-81	289.0	COG0600@1|root,COG0600@2|Bacteria,3Y5KR@57723|Acidobacteria,2JNDD@204432|Acidobacteriia	204432|Acidobacteriia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158456_k127_790546_1	1267535.KB906767_gene3874	4.272e-138	444.0	COG0715@1|root,COG0715@2|Bacteria,3Y5UN@57723|Acidobacteria,2JNY2@204432|Acidobacteriia	204432|Acidobacteriia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158456_k127_790546_14	234267.Acid_4815	3.801e-26	111.0	COG3682@1|root,COG3682@2|Bacteria,3Y8BB@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
SRR25158456_k127_790546_10	861299.J421_1974	2.868e-40	169.0	COG3595@1|root,COG4219@1|root,COG3595@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	DUF4097
SRR25158456_k127_790546_2	1123377.AUIV01000025_gene381	8.729e-133	450.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,1X4WG@135614|Xanthomonadales	135614|Xanthomonadales	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SRR25158456_k127_790546_9	765910.MARPU_12315	1.848e-46	179.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158456_k127_790546_17	290397.Adeh_1701	4.201e-06	57.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158456_k127_790546_4	1265503.KB905160_gene2836	2.145e-108	359.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,2Q5WU@267889|Colwelliaceae	1236|Gammaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
SRR25158456_k127_794424_0	1191523.MROS_2755	3.153e-149	481.0	COG0160@1|root,COG0160@2|Bacteria	2|Bacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36	ko:K00821,ko:K03918,ko:K07250,ko:K13524	ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727	M00016,M00027,M00028,M00845	R00457,R00908,R01648,R02283,R04188,R04475	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv3290c	Aminotran_3
SRR25158456_k127_794424_1	497965.Cyan7822_3913	1.57e-10	66.0	COG3239@1|root,COG3239@2|Bacteria,1GJ4V@1117|Cyanobacteria,3KKI6@43988|Cyanothece	1117|Cyanobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158456_k127_800290_0	1254432.SCE1572_41675	2.925e-218	690.0	COG4650@1|root,COG4650@2|Bacteria,1MX6U@1224|Proteobacteria,42NHB@68525|delta/epsilon subdivisions,2WKUB@28221|Deltaproteobacteria,2YTU9@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-54 dependent transcriptional regulator	rtcR	-	-	ko:K14414	-	-	-	-	ko00000,ko03000	-	-	-	RtcR,Sigma54_activat
SRR25158456_k127_800290_1	595537.Varpa_5106	1.199e-194	621.0	COG2425@1|root,COG2425@2|Bacteria,1R55U@1224|Proteobacteria,2VKRA@28216|Betaproteobacteria,4AC01@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K11089	ko05322,map05322	-	-	-	ko00000,ko00001	-	-	-	TROVE
SRR25158456_k127_800290_2	204669.Acid345_1273	9.446e-194	611.0	COG1690@1|root,COG1690@2|Bacteria,3Y82C@57723|Acidobacteria,2JN64@204432|Acidobacteriia	204432|Acidobacteriia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SRR25158456_k127_800290_3	1254432.SCE1572_41685	2.425e-103	347.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,42MZG@68525|delta/epsilon subdivisions,2WKZ3@28221|Deltaproteobacteria,2YTT5@29|Myxococcales	28221|Deltaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
SRR25158456_k127_800290_4	551275.KB899545_gene2494	6.057e-12	77.0	2BG0P@1|root,329WQ@2|Bacteria,1P9AZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_803636_1	342113.DM82_4935	1.975e-96	349.0	COG2304@1|root,COG2304@2|Bacteria,1R88T@1224|Proteobacteria,2VVPK@28216|Betaproteobacteria,1KBGQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Common central domain of tyrosinase	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	PPC,Tyrosinase
SRR25158456_k127_803636_5	1150600.ADIARSV_3503	5.373e-22	106.0	2DNPP@1|root,32YG6@2|Bacteria,4P6QS@976|Bacteroidetes,1IZIS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_803636_2	1150600.ADIARSV_3502	1.41e-77	284.0	COG1999@1|root,COG1999@2|Bacteria,4P453@976|Bacteroidetes,1IYEF@117747|Sphingobacteriia	976|Bacteroidetes	S	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	SCO1-SenC
SRR25158456_k127_803636_6	536019.Mesop_4244	5.071e-18	95.0	COG0671@1|root,COG0671@2|Bacteria,1RF6B@1224|Proteobacteria,2U8U5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158456_k127_803636_7	1550073.JROH01000023_gene835	6.66e-10	63.0	COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,2UKAZ@28211|Alphaproteobacteria,2K85R@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158456_k127_803636_8	555779.Dthio_PD0442	5.125e-08	57.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,42VXJ@68525|delta/epsilon subdivisions,2WRHC@28221|Deltaproteobacteria,2MFG7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_803636_0	671143.DAMO_2498	5.892e-154	496.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158456_k127_803636_4	330214.NIDE2482	1.919e-25	111.0	COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158456_k127_803636_3	1123377.AUIV01000016_gene370	3.529e-31	134.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,1S4MG@1236|Gammaproteobacteria,1X4H4@135614|Xanthomonadales	135614|Xanthomonadales	S	Alpha beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
SRR25158456_k127_812755_3	1232410.KI421412_gene116	4.236e-91	308.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42NZP@68525|delta/epsilon subdivisions,2WKZA@28221|Deltaproteobacteria,43S59@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158456_k127_812755_7	583355.Caka_2847	3.142e-47	176.0	COG1017@1|root,COG1017@2|Bacteria,46Z2G@74201|Verrucomicrobia,3K9UI@414999|Opitutae	414999|Opitutae	C	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_812755_9	1123033.ARNF01000035_gene2536	5.704e-24	109.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria	1224|Proteobacteria	S	-acetyltransferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158456_k127_812755_0	671143.DAMO_0012	3.129e-201	655.0	COG1966@1|root,COG1966@2|Bacteria,2NNP2@2323|unclassified Bacteria	2|Bacteria	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158456_k127_812755_10	1089550.ATTH01000001_gene2148	0.0003959	49.0	COG2968@1|root,COG2968@2|Bacteria,4P8H6@976|Bacteroidetes,1FJN4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SRR25158456_k127_812755_8	861299.J421_2064	4.282e-27	129.0	COG5531@1|root,COG5531@2|Bacteria,1ZTZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
SRR25158456_k127_812755_6	622637.KE124774_gene2034	7.375e-50	190.0	2AUD4@1|root,31K11@2|Bacteria,1RI0U@1224|Proteobacteria,2U998@28211|Alphaproteobacteria,36YHR@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158456_k127_812755_2	379066.GAU_1368	4.158e-130	427.0	COG0498@1|root,COG0498@2|Bacteria,1ZSVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_812755_5	269798.CHU_0074	3.675e-54	202.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,47KGY@768503|Cytophagia	976|Bacteroidetes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158456_k127_812755_1	379066.GAU_1367	2.47e-197	646.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1ZSSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ACT domain	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
SRR25158456_k127_812755_4	264462.Bd3487	1.836e-75	260.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2MT3P@213481|Bdellovibrionales,2WNJ6@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158456_k127_831716_3	319795.Dgeo_2541	2.034e-10	72.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158456_k127_831716_1	748658.KB907313_gene2306	1.398e-61	217.0	COG4636@1|root,COG4636@2|Bacteria,1RH3Z@1224|Proteobacteria,1SNYB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_831716_2	1038862.KB893805_gene4085	3.976e-37	154.0	29ZGM@1|root,30MGC@2|Bacteria,1R3RJ@1224|Proteobacteria,2U2CI@28211|Alphaproteobacteria,3JXNV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_831716_0	1185876.BN8_06612	9.46e-69	248.0	COG1835@1|root,COG1835@2|Bacteria,4NFYX@976|Bacteroidetes,47MCE@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158456_k127_831993_6	1071085.KK033114_gene1458	9.25e-17	87.0	COG1331@1|root,arCOG02007@2157|Archaea,2XT1C@28890|Euryarchaeota,23SUJ@183963|Halobacteria	183963|Halobacteria	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
SRR25158456_k127_831993_1	709986.Deima_2588	1.172e-49	196.0	COG1131@1|root,COG1131@2|Bacteria,1WJ0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_831993_7	240015.ACP_1829	6.696e-13	76.0	2DNS7@1|root,32YWC@2|Bacteria,3Y609@57723|Acidobacteria,2JK5C@204432|Acidobacteriia	204432|Acidobacteriia	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158456_k127_831993_4	1249480.B649_04605	3.916e-29	130.0	2BYFR@1|root,32R3B@2|Bacteria,1NSDG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_831993_0	639282.DEFDS_1924	9.738e-50	192.0	COG0568@1|root,COG0568@2|Bacteria,2GEUB@200930|Deferribacteres	200930|Deferribacteres	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158456_k127_831993_9	234267.Acid_3707	1.569e-09	66.0	2EGKM@1|root,33ACV@2|Bacteria,3Y5U1@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_831993_3	1267535.KB906767_gene3332	6.002e-37	151.0	2DKN8@1|root,32UFB@2|Bacteria,3Y55I@57723|Acidobacteria,2JJU7@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
SRR25158456_k127_831993_8	1267535.KB906767_gene3331	7.052e-11	70.0	2ERSC@1|root,33JBJ@2|Bacteria,3Y5XV@57723|Acidobacteria,2JK5S@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_831993_2	1267535.KB906767_gene3330	1.627e-37	150.0	COG1595@1|root,COG1595@2|Bacteria,3Y5BF@57723|Acidobacteria,2JJZZ@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158456_k127_831993_5	1278073.MYSTI_01189	2.547e-26	117.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	ko:K02200,ko:K04018	-	-	-	-	ko00000	-	-	-	DUF4388,TPR_16,TPR_19
SRR25158456_k127_850302_2	1122138.AQUZ01000003_gene462	2.93e-31	132.0	COG3832@1|root,COG3832@2|Bacteria,2IG6F@201174|Actinobacteria,4DR5W@85009|Propionibacteriales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158456_k127_850302_3	298654.FraEuI1c_3042	8.184e-27	113.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158456_k127_850302_4	762903.Pedsa_1290	3.117e-22	101.0	2DS4P@1|root,33EH8@2|Bacteria,4PPZ4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_850302_1	269798.CHU_3113	1.887e-48	188.0	295WE@1|root,2ZT7B@2|Bacteria,4NXBS@976|Bacteroidetes,47VZ0@768503|Cytophagia	976|Bacteroidetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
SRR25158456_k127_850302_5	521674.Plim_3220	1.647e-20	104.0	COG5635@1|root,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TIR_2
SRR25158456_k127_850302_0	204669.Acid345_1097	5.497e-175	556.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158456_k127_859443_12	404589.Anae109_0955	3.755e-18	85.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SRR25158456_k127_859443_10	1317122.ATO12_10895	2.149e-33	135.0	COG1443@1|root,COG1443@2|Bacteria,4NRS2@976|Bacteroidetes,1I2UY@117743|Flavobacteriia,2YJ7E@290174|Aquimarina	976|Bacteroidetes	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158456_k127_859443_11	1340493.JNIF01000003_gene1314	9.974e-23	104.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158456_k127_859443_4	330214.NIDE4312	3.219e-133	431.0	COG0330@1|root,COG0330@2|Bacteria,3J0NF@40117|Nitrospirae	40117|Nitrospirae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158456_k127_859443_8	1192034.CAP_7790	3.409e-97	342.0	COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,438CS@68525|delta/epsilon subdivisions,2WYMI@28221|Deltaproteobacteria,2YWK8@29|Myxococcales	28221|Deltaproteobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	3.4.24.25	ko:K08604	ko05110,ko05111,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PPC,Peptidase_M4,Peptidase_M4_C
SRR25158456_k127_859443_9	1163407.UU7_15465	1.471e-93	318.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XCEX@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158456_k127_859443_0	1121124.JNIX01000015_gene2040	1.589e-188	628.0	COG1629@1|root,COG4771@2|Bacteria,1PSM0@1224|Proteobacteria,2U3MX@28211|Alphaproteobacteria,2KHTG@204458|Caulobacterales	204458|Caulobacterales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
SRR25158456_k127_859443_2	1300345.LF41_892	1.147e-161	559.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria,1RY8M@1236|Gammaproteobacteria,1X3JA@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
SRR25158456_k127_859443_5	215803.DB30_8575	3.836e-105	375.0	COG1653@1|root,COG1653@2|Bacteria,1MX59@1224|Proteobacteria	1224|Proteobacteria	G	ABC transporter substrate-binding protein	malE	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158456_k127_859443_6	945713.IALB_1188	3.444e-101	357.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	lacF	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158456_k127_859443_7	743721.Psesu_1286	3.038e-100	338.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,1S4G6@1236|Gammaproteobacteria,1X3NS@135614|Xanthomonadales	135614|Xanthomonadales	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158456_k127_859443_1	1205753.A989_16188	6.548e-171	580.0	COG3408@1|root,COG3408@2|Bacteria,1QU1Q@1224|Proteobacteria,1RRX2@1236|Gammaproteobacteria,1X4YN@135614|Xanthomonadales	135614|Xanthomonadales	G	coagulation factor 5 8 type	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,F5_F8_type_C,GDE_C
SRR25158456_k127_859443_3	403833.Pmob_0953	2.802e-133	443.0	COG3459@1|root,COG3459@2|Bacteria,2GCQM@200918|Thermotogae	200918|Thermotogae	G	Cellobiose phosphorylase	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
SRR25158456_k127_862903_3	204669.Acid345_0995	1.727e-132	435.0	COG3191@1|root,COG3191@2|Bacteria,3Y699@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158456_k127_862903_6	1282360.ABAC460_20050	6.411e-60	226.0	COG0666@1|root,COG0666@2|Bacteria,1NH1G@1224|Proteobacteria	1224|Proteobacteria	S	FOG Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
SRR25158456_k127_862903_7	1161401.ASJA01000033_gene3043	1.976e-12	78.0	2DEWU@1|root,2ZPJP@2|Bacteria,1NBPN@1224|Proteobacteria,2VGJK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_862903_4	945550.VISI1226_17996	6.618e-65	235.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1XTHQ@135623|Vibrionales	135623|Vibrionales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158456_k127_862903_5	472759.Nhal_3405	2.021e-64	241.0	COG4948@1|root,COG4948@2|Bacteria,1REK2@1224|Proteobacteria,1S4AA@1236|Gammaproteobacteria,1X1XR@135613|Chromatiales	135613|Chromatiales	M	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
SRR25158456_k127_862903_1	472759.Nhal_3406	1.86e-150	492.0	COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,1RNHW@1236|Gammaproteobacteria,1WXBX@135613|Chromatiales	135613|Chromatiales	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158456_k127_862903_2	861299.J421_0426	5.442e-145	471.0	COG0458@1|root,COG0458@2|Bacteria,1ZTAX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp
SRR25158456_k127_862903_0	861299.J421_0425	1.273e-155	502.0	COG0151@1|root,COG0151@2|Bacteria,1ZSWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158456_k127_862903_8	604331.AUHY01000021_gene1976	2.323e-07	62.0	2BAVZ@1|root,324BI@2|Bacteria,1WJT7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
SRR25158456_k127_868763_6	1121920.AUAU01000030_gene2723	1.054e-07	54.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158456_k127_868763_1	1254432.SCE1572_41455	4.53e-136	443.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158456_k127_868763_2	383372.Rcas_0286	7.656e-77	263.0	COG1011@1|root,COG1011@2|Bacteria,2G916@200795|Chloroflexi,377HS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158456_k127_868763_5	1218076.BAYB01000022_gene3941	3.094e-29	129.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2W4WI@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
SRR25158456_k127_868763_7	1146883.BLASA_0330	1.089e-05	53.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_868763_3	1267211.KI669560_gene2103	1.755e-57	213.0	COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,1IP9F@117747|Sphingobacteriia	976|Bacteroidetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SRR25158456_k127_868763_4	247490.KSU1_C0103	1.144e-43	173.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SRR25158456_k127_868763_0	1519464.HY22_07105	1.318e-274	872.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158456_k127_869393_3	1047013.AQSP01000134_gene1379	1.564e-08	61.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158456_k127_869393_0	748280.NH8B_0055	2.301e-146	474.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,2KQFQ@206351|Neisseriales	206351|Neisseriales	E	Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SRR25158456_k127_869393_1	335543.Sfum_1218	3.416e-67	253.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,2MQ61@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158456_k127_869393_2	269799.Gmet_1249	2.077e-20	95.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,43T2W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
SRR25158456_k127_883971_4	8932.XP_005508415.1	7.932e-06	53.0	2CW9H@1|root,2RTXW@2759|Eukaryota,38VYN@33154|Opisthokonta,3CCXZ@33208|Metazoa,3DM6X@33213|Bilateria,48K21@7711|Chordata,49IU4@7742|Vertebrata,4GWIB@8782|Aves	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_883971_2	931276.Cspa_c40240	7.672e-51	192.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,36DJ0@31979|Clostridiaceae	186801|Clostridia	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158456_k127_883971_1	251221.35210997	1.573e-93	313.0	COG1131@1|root,COG1131@2|Bacteria,1G0BQ@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_883971_0	251221.35210998	3.441e-96	343.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_883971_3	234267.Acid_1289	2.692e-31	129.0	2DEWU@1|root,2ZPJP@2|Bacteria,3Y585@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_895883_0	580331.Thit_1277	8.299e-57	207.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,42FUI@68295|Thermoanaerobacterales	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158456_k127_895883_6	269799.Gmet_1854	2.436e-39	162.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,43SYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
SRR25158456_k127_895883_4	224324.aq_797	8.199e-47	187.0	COG0793@1|root,COG0793@2|Bacteria,2G3RT@200783|Aquificae	200783|Aquificae	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158456_k127_895883_10	292564.Cyagr_2278	5.984e-06	53.0	COG4118@1|root,COG4118@2|Bacteria,1GJQY@1117|Cyanobacteria,22TH9@167375|Cyanobium	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158456_k127_895883_2	1040989.AWZU01000077_gene6559	9.95e-55	194.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158456_k127_895883_1	1254432.SCE1572_52480	2.436e-56	203.0	COG4636@1|root,COG4636@2|Bacteria,1RH5Y@1224|Proteobacteria,42WNQ@68525|delta/epsilon subdivisions,2WSHW@28221|Deltaproteobacteria,2Z378@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SRR25158456_k127_895883_5	269799.Gmet_1850	6.611e-46	178.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,42RJN@68525|delta/epsilon subdivisions,2WNEI@28221|Deltaproteobacteria,43SZ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
SRR25158456_k127_895883_3	1267533.KB906735_gene4549	2.851e-50	189.0	COG0515@1|root,COG0515@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158456_k127_895883_8	314230.DSM3645_01776	2.856e-14	82.0	2EEQZ@1|root,338IP@2|Bacteria,2J15B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_895883_9	69395.JQLZ01000006_gene2140	2.118e-09	61.0	COG4456@1|root,COG4456@2|Bacteria,1PQDA@1224|Proteobacteria,2UKEQ@28211|Alphaproteobacteria,2KJH4@204458|Caulobacterales	204458|Caulobacterales	S	SpoVT / AbrB like domain	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
SRR25158456_k127_895883_7	1485543.JMME01000003_gene1906	4.981e-29	121.0	COG1487@1|root,COG1487@2|Bacteria,1VCFS@1239|Firmicutes,4H7VU@909932|Negativicutes	909932|Negativicutes	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158456_k127_903184_0	497964.CfE428DRAFT_0230	4.587e-116	401.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,46TGZ@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158456_k127_903184_1	1254432.SCE1572_42680	2.475e-34	139.0	COG3652@1|root,COG3652@2|Bacteria,1N6QU@1224|Proteobacteria,43271@68525|delta/epsilon subdivisions,2WXXM@28221|Deltaproteobacteria,2Z022@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
SRR25158456_k127_903184_5	63737.Npun_R5488	1.841e-17	83.0	2E4DR@1|root,32Z92@2|Bacteria,1G9TM@1117|Cyanobacteria,1HPVP@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_903184_3	643473.KB235930_gene3771	1.105e-25	109.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7MJ@1117|Cyanobacteria,1HU1X@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_903184_2	261292.Nit79A3_2066	2.26e-32	140.0	2ER3Y@1|root,33IPI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_903184_6	483219.LILAB_18790	1.002e-10	78.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K14475,ko:K20276	ko02024,ko05143,map02024,map05143	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,RCC1_2
SRR25158456_k127_903184_4	1297742.A176_00743	1.833e-18	104.0	COG3210@1|root,COG4257@1|root,COG5276@1|root,COG3210@2|Bacteria,COG4257@2|Bacteria,COG5276@2|Bacteria,1R2UD@1224|Proteobacteria,43DGX@68525|delta/epsilon subdivisions,2X8NS@28221|Deltaproteobacteria,2Z130@29|Myxococcales	28221|Deltaproteobacteria	U	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158456_k127_90569_2	1121920.AUAU01000022_gene2487	1.151e-51	193.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_90569_3	880073.Calab_3273	3.813e-41	165.0	COG3852@1|root,COG3852@2|Bacteria,2NS4D@2323|unclassified Bacteria	2|Bacteria	T	Signal transduction histidine kinase, nitrogen specific, NtrB	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
SRR25158456_k127_90569_0	331678.Cphamn1_0516	2.654e-78	280.0	COG4912@1|root,COG4912@2|Bacteria,1FDUX@1090|Chlorobi	1090|Chlorobi	L	PFAM DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158456_k127_90569_1	887898.HMPREF0551_2095	3.893e-64	226.0	COG1571@1|root,COG1571@2|Bacteria,1QVS8@1224|Proteobacteria,2VI63@28216|Betaproteobacteria	28216|Betaproteobacteria	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_906309_5	397948.Cmaq_0099	1.708e-05	52.0	COG5550@1|root,arCOG03744@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_906309_1	452637.Oter_1902	7.91e-126	417.0	COG5000@1|root,COG5000@2|Bacteria,46V9C@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158456_k127_906309_0	926566.Terro_2393	6.128e-169	543.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158456_k127_906309_3	1340493.JNIF01000003_gene4407	1.786e-95	318.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_906309_2	204669.Acid345_0618	2.219e-120	416.0	COG0577@1|root,COG0577@2|Bacteria,3Y6E4@57723|Acidobacteria,2JM2S@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SRR25158456_k127_912603_0	349520.PPE_03010	5.102e-310	988.0	COG0236@1|root,COG2227@1|root,COG3321@1|root,COG4221@1|root,COG0236@2|Bacteria,COG2227@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1VU8Z@1239|Firmicutes,4HFCI@91061|Bacilli,2771J@186822|Paenibacillaceae	91061|Bacilli	Q	Polyketide synthase modules and related proteins	pksL	-	-	ko:K13613,ko:K13614	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	ECH_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158456_k127_9162_3	1121920.AUAU01000023_gene2418	1.791e-69	244.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158456_k127_9162_5	56780.SYN_02636	9.019e-64	231.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158456_k127_9162_7	1267535.KB906767_gene2339	1.192e-29	121.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria,2JNEQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
SRR25158456_k127_9162_4	1461694.ATO9_16525	2.505e-68	242.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2PC9N@252301|Oceanicola	28211|Alphaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158456_k127_9162_1	1459636.NTE_02739	1.14e-105	349.0	COG1741@1|root,arCOG02935@2157|Archaea	2157|Archaea	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158456_k127_9162_8	426716.JOAJ01000001_gene1506	3.741e-16	88.0	COG0561@1|root,COG0637@1|root,COG1554@1|root,COG0561@2|Bacteria,COG0637@2|Bacteria,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4FU49@85025|Nocardiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	otsB1	GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	3.1.3.12,3.2.1.28	ko:K01087,ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010,R02778	RC00017,RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,Hydrolase,Trehalose_PPase
SRR25158456_k127_9162_0	1187851.A33M_0762	8.513e-145	475.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,3FCZJ@34008|Rhodovulum	28211|Alphaproteobacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158456_k127_9162_2	648996.Theam_1712	3.216e-75	263.0	COG0496@1|root,COG0496@2|Bacteria,2G3WU@200783|Aquificae	200783|Aquificae	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158456_k127_9162_6	1121403.AUCV01000021_gene3550	2.586e-60	218.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MHNG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158456_k127_924560_4	1169161.KB897740_gene2260	8.548e-18	90.0	2BZFB@1|root,34193@2|Bacteria,2GW33@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_924560_6	479433.Caci_5695	2.267e-08	61.0	2931M@1|root,2ZQIW@2|Bacteria,2H1EZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_924560_3	479433.Caci_5694	1.444e-26	119.0	2F8ZD@1|root,341B4@2|Bacteria,2GVRF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_924560_5	1169161.KB897740_gene2257	3.442e-15	86.0	2EM19@1|root,33EQT@2|Bacteria,2GX04@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_924560_1	1123298.KB904062_gene873	6.091e-61	220.0	COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli	91061|Bacilli	E	abc transporter atp-binding protein	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158456_k127_924560_2	1173023.KE650771_gene251	4.219e-59	212.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1JHEY@1189|Stigonemataceae	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158456_k127_924560_0	118173.KB235914_gene2353	4.346e-80	275.0	COG1732@1|root,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1H9PY@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158456_k127_924560_7	246194.CHY_0526	1.151e-05	55.0	2DRSH@1|root,33CVS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_932485_0	883126.HMPREF9710_00067	9.031e-145	481.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158456_k127_932485_8	1157490.EL26_06795	8.76e-21	110.0	COG4733@1|root,COG4733@2|Bacteria,1UEBB@1239|Firmicutes,4HB9W@91061|Bacilli	91061|Bacilli	N	Fibronectin type 3 domain	Tnr	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	SLH,fn3
SRR25158456_k127_932485_1	378806.STAUR_6060	4.911e-105	364.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2Z30A@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158456_k127_932485_4	903818.KI912268_gene709	3.895e-64	236.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	DUF697,MMR_HSR1
SRR25158456_k127_932485_6	234267.Acid_0471	8.336e-27	111.0	COG1193@1|root,COG1193@2|Bacteria,3Y8PZ@57723|Acidobacteria	57723|Acidobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SRR25158456_k127_932485_3	289376.THEYE_A0564	8.434e-89	303.0	COG0379@1|root,COG0379@2|Bacteria,3J0NV@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158456_k127_932485_5	1500894.JQNN01000001_gene529	4.02e-37	151.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2VZ36@28216|Betaproteobacteria,472UX@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158456_k127_932485_2	1047013.AQSP01000123_gene1523	4.61e-102	371.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
SRR25158456_k127_933233_2	926550.CLDAP_11560	5.333e-29	117.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158456_k127_933233_1	1128421.JAGA01000002_gene375	1.07e-47	182.0	COG2003@1|root,COG2003@2|Bacteria,2NPI9@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158456_k127_933233_4	1089544.KB912942_gene4164	3.647e-13	83.0	COG0760@1|root,COG0760@2|Bacteria,2IGXV@201174|Actinobacteria	201174|Actinobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158456_k127_933233_3	483219.LILAB_06345	2.159e-24	115.0	COG0760@1|root,COG0760@2|Bacteria,1RKBZ@1224|Proteobacteria,42SAP@68525|delta/epsilon subdivisions,2WPWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
SRR25158456_k127_933233_0	204669.Acid345_4549	3.521e-285	912.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158456_k127_936180_0	290315.Clim_2424	4.7e-178	574.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158456_k127_936180_2	1117108.PAALTS15_19743	1.231e-19	93.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,26Z1F@186822|Paenibacillaceae	91061|Bacilli	K	GntR family transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158456_k127_936180_1	1123242.JH636434_gene4731	2.437e-45	180.0	COG1131@1|root,COG1131@2|Bacteria,2IZVY@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158456_k127_937575_3	867845.KI911784_gene2572	9.141e-30	132.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158456_k127_937575_1	1406840.Q763_09675	1.786e-51	197.0	COG2318@1|root,COG2318@2|Bacteria,4NMXH@976|Bacteroidetes,1I32M@117743|Flavobacteriia	976|Bacteroidetes	S	Damage-inducible protein DinB	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158456_k127_937575_2	314278.NB231_14333	3.128e-33	150.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria,1S6QY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158456_k127_937575_0	1192034.CAP_4786	4.652e-73	272.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SRR25158456_k127_937575_4	710111.FraQA3DRAFT_5653	4.108e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,2I2Z1@201174|Actinobacteria,4ETFB@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158456_k127_948860_12	543728.Vapar_0172	3.495e-12	79.0	COG1807@1|root,COG1807@2|Bacteria,1N02M@1224|Proteobacteria,2W18W@28216|Betaproteobacteria,4AHD0@80864|Comamonadaceae	28216|Betaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_948860_10	314278.NB231_03105	4.208e-14	78.0	COG3668@1|root,COG3668@2|Bacteria,1QSS3@1224|Proteobacteria,1SRQZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_948860_4	1340493.JNIF01000003_gene1371	1.469e-88	300.0	COG1741@1|root,COG1741@2|Bacteria,3Y831@57723|Acidobacteria	57723|Acidobacteria	S	Pirin C-terminal cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
SRR25158456_k127_948860_6	1184267.A11Q_1018	2.493e-41	175.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2MTBA@213481|Bdellovibrionales,2WM41@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SRR25158456_k127_948860_13	596151.DesfrDRAFT_0705	1.016e-10	72.0	2E17X@1|root,32WNJ@2|Bacteria,1N3GY@1224|Proteobacteria,42TVS@68525|delta/epsilon subdivisions,2WQQD@28221|Deltaproteobacteria,2MCN4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM cytochrome c class III	tmcA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
SRR25158456_k127_948860_0	264462.Bd2174	1e-323	1010.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2MTS8@213481|Bdellovibrionales,2WTI2@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Domain of unknown function (DUF1974)	-	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
SRR25158456_k127_948860_7	316057.RPD_1835	1.477e-35	140.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,3JQSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_16590	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158456_k127_948860_3	1396418.BATQ01000149_gene2216	1.121e-97	335.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
SRR25158456_k127_948860_14	935948.KE386495_gene1210	0.0002845	49.0	COG1476@1|root,COG1476@2|Bacteria,1UV44@1239|Firmicutes,24S0P@186801|Clostridia,42HKI@68295|Thermoanaerobacterales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRR25158456_k127_948860_5	1320556.AVBP01000002_gene4161	5.248e-42	168.0	COG4487@1|root,COG4487@2|Bacteria,1MWNT@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
SRR25158456_k127_948860_2	348824.LPU83_pLPU83a_0048	1.062e-115	392.0	29X5E@1|root,30IUE@2|Bacteria,1NS25@1224|Proteobacteria,2UPR4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158456_k127_948860_1	1242864.D187_002113	3.957e-200	654.0	COG4412@1|root,COG4412@2|Bacteria,1P5IH@1224|Proteobacteria	1224|Proteobacteria	O	Peptidase M6, immune inhibitor A	ina	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
SRR25158456_k127_948860_11	290317.Cpha266_2673	2.303e-13	75.0	COG0724@1|root,COG0724@2|Bacteria,1FE64@1090|Chlorobi	1090|Chlorobi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158456_k127_948860_8	1210884.HG799464_gene11143	1.405e-19	91.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158456_k127_948860_9	1121288.AULL01000015_gene183	5.243e-19	94.0	2CK2Y@1|root,32SBF@2|Bacteria,4NTZD@976|Bacteroidetes,1I4T5@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Photosynthetic reaction centre cytochrome C subunit	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	CytoC_RC
SRR25158456_k127_968207_0	1279009.ADICEAN_02616	3.399e-13	81.0	COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158456_k127_968207_1	1336235.JAEG01000001_gene2125	0.0008302	46.0	COG4625@1|root,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria,2U54N@28211|Alphaproteobacteria,4BB7H@82115|Rhizobiaceae	28211|Alphaproteobacteria	MU	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,He_PIG,fn3
SRR25158456_k127_972184_2	1174684.EBMC1_04529	3.439e-33	135.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,2K0WW@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158456_k127_972184_3	425104.Ssed_2739	4.569e-28	128.0	COG0845@1|root,COG0845@2|Bacteria,1P5GT@1224|Proteobacteria,1S7A6@1236|Gammaproteobacteria,2Q8V8@267890|Shewanellaceae	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
SRR25158456_k127_972184_4	385682.AFSL01000005_gene978	2.075e-21	110.0	COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,2FY71@200643|Bacteroidia,3XJW6@558415|Marinilabiliaceae	976|Bacteroidetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
SRR25158456_k127_972184_1	392500.Swoo_1902	1.194e-57	227.0	COG0845@1|root,COG0845@2|Bacteria,1RCT0@1224|Proteobacteria,1S3AD@1236|Gammaproteobacteria,2QABY@267890|Shewanellaceae	1236|Gammaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
SRR25158456_k127_972184_0	1042377.AFPJ01000019_gene2484	1.112e-104	354.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1RMBY@1236|Gammaproteobacteria,46A44@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158456_k127_972184_5	215803.DB30_0674	9.782e-13	75.0	COG1196@1|root,COG4219@1|root,COG1196@2|Bacteria,COG4219@2|Bacteria,1PEGJ@1224|Proteobacteria,438JW@68525|delta/epsilon subdivisions,2X3UI@28221|Deltaproteobacteria,2YX4Y@29|Myxococcales	28221|Deltaproteobacteria	DKT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
SRR25158456_k127_980163_10	439235.Dalk_4490	1.463e-67	242.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
SRR25158456_k127_980163_9	765910.MARPU_14405	8.949e-69	249.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WVXU@135613|Chromatiales	135613|Chromatiales	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158456_k127_980163_6	666685.R2APBS1_2336	1.898e-104	342.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,1S5G9@1236|Gammaproteobacteria,1X7TI@135614|Xanthomonadales	135614|Xanthomonadales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158456_k127_980163_1	84531.JMTZ01000009_gene3270	1.117e-231	738.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RRWF@1236|Gammaproteobacteria,1X4FU@135614|Xanthomonadales	135614|Xanthomonadales	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158456_k127_980163_15	234267.Acid_5031	3.519e-36	143.0	COG1846@1|root,COG1846@2|Bacteria,3Y5EQ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158456_k127_980163_11	861299.J421_0860	2.135e-65	228.0	COG2353@1|root,COG2353@2|Bacteria,1ZV1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158456_k127_980163_4	1278073.MYSTI_01749	4.681e-126	411.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,42Y59@68525|delta/epsilon subdivisions,2WTYB@28221|Deltaproteobacteria,2YUUN@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158456_k127_980163_0	483219.LILAB_05395	4.375e-262	865.0	COG0308@1|root,COG0308@2|Bacteria,1PTWJ@1224|Proteobacteria,42YQD@68525|delta/epsilon subdivisions,2WU66@28221|Deltaproteobacteria,2YXEH@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158456_k127_980163_7	251221.35213336	5.563e-98	327.0	COG1718@1|root,COG1718@2|Bacteria,1G3HN@1117|Cyanobacteria	1117|Cyanobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_980163_14	215803.DB30_2063	6.812e-44	165.0	2CP0Z@1|root,32SI8@2|Bacteria,1RK5X@1224|Proteobacteria,434SF@68525|delta/epsilon subdivisions,2X904@28221|Deltaproteobacteria,2Z0HI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158456_k127_980163_5	1198452.Jab_2c17530	1.521e-122	416.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,47743@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158456_k127_980163_3	526227.Mesil_2489	4.176e-133	441.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158456_k127_980163_13	1321778.HMPREF1982_01561	1.143e-44	177.0	COG1573@1|root,COG1573@2|Bacteria,1VGX6@1239|Firmicutes,25DJZ@186801|Clostridia	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158456_k127_980163_17	240292.Ava_2498	4.721e-23	101.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria,1HPUY@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158456_k127_980163_16	449447.MAE_18190	9.619e-27	112.0	COG4634@1|root,COG4634@2|Bacteria,1G71Y@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158456_k127_980163_2	1382304.JNIL01000001_gene3015	7.169e-152	486.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,279ER@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR25158456_k127_980163_8	1340493.JNIF01000003_gene2147	1.298e-71	251.0	COG2382@1|root,COG2382@2|Bacteria,3Y68C@57723|Acidobacteria	57723|Acidobacteria	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158456_k127_980163_12	357808.RoseRS_4322	1.239e-48	179.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi,375VA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158456_k127_99710_1	861299.J421_0892	1.222e-30	126.0	COG0076@1|root,COG0076@2|Bacteria,1ZTFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
SRR25158456_k127_99710_0	243231.GSU1475	8.759e-45	177.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158456_k127_99710_2	1254432.SCE1572_48280	3.049e-16	85.0	COG0784@1|root,COG0784@2|Bacteria,1QAM7@1224|Proteobacteria,43563@68525|delta/epsilon subdivisions,2WZH3@28221|Deltaproteobacteria,2Z24X@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
## 4491 queries scanned
## Total time (seconds): 6.197948455810547
## Rate: 724.59 q/s