## Mon Dec 15 15:32:50 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158462_bin.10.fa -m mmseqs --itype genome -o SRR25158462_bin.10 --output_dir /data/result/bins/wyx/egg/SRR25158462_bin.10 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158462_k127_1055056_3	469383.Cwoe_5227	8.017e-13	68.0	COG2220@1|root,COG2220@2|Bacteria,2HP2V@201174|Actinobacteria,4CQDX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158462_k127_1055056_1	469383.Cwoe_5222	2.328e-127	417.0	COG0208@1|root,COG0208@2|Bacteria,2GK48@201174|Actinobacteria,4CSBG@84995|Rubrobacteria	84995|Rubrobacteria	F	Ribonucleotide reductase, small chain	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRR25158462_k127_1055056_2	469383.Cwoe_5221	3.323e-102	351.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4CPHK@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_1055056_0	1283299.AUKG01000003_gene610	1.206e-178	569.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CRM8@84995|Rubrobacteria	84995|Rubrobacteria	EH	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158462_k127_1084732_57	1157637.KB892090_gene6477	6.93e-100	342.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158462_k127_1084732_94	469383.Cwoe_0770	2.843e-54	203.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4CQ70@84995|Rubrobacteria	84995|Rubrobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158462_k127_1084732_124	469383.Cwoe_0769	6.006e-22	104.0	2B9V4@1|root,32383@2|Bacteria,2HRXS@201174|Actinobacteria,4CU12@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_20	469383.Cwoe_0768	1.407e-157	510.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CPRJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158462_k127_1084732_116	1147.D082_25660	1.136e-25	122.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
SRR25158462_k127_1084732_97	469383.Cwoe_4651	4.435e-52	191.0	COG3917@1|root,COG3917@2|Bacteria,2HPCS@201174|Actinobacteria,4CQQS@84995|Rubrobacteria	84995|Rubrobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158462_k127_1084732_60	479434.Sthe_1935	1.428e-96	329.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi,27XY9@189775|Thermomicrobia	189775|Thermomicrobia	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158462_k127_1084732_44	1209984.BN978_04202	1.886e-110	384.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,233TJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158462_k127_1084732_56	469383.Cwoe_0793	1.062e-100	351.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4CRDF@84995|Rubrobacteria	84995|Rubrobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_93	1283299.AUKG01000001_gene1509	1.077e-54	218.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4CQ38@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158462_k127_1084732_120	1396141.BATP01000038_gene1225	5.883e-25	120.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46VP8@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
SRR25158462_k127_1084732_144	309801.trd_0141	5.774e-11	75.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Metallophos,fn3
SRR25158462_k127_1084732_17	469383.Cwoe_0743	1.077e-162	516.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4CPF1@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158462_k127_1084732_125	870967.VIS19158_07490	9.478e-22	109.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH
SRR25158462_k127_1084732_129	1380390.JIAT01000010_gene4769	2.648e-19	95.0	2DS52@1|root,33EJF@2|Bacteria,2H1N9@201174|Actinobacteria,4CST5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_141	110319.CF8_1052	4.788e-12	72.0	2DZGK@1|root,32VA1@2|Bacteria,2IJIB@201174|Actinobacteria,4DUUY@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_5
SRR25158462_k127_1084732_139	469383.Cwoe_0702	1.69e-12	78.0	2B5BB@1|root,31Y5H@2|Bacteria,2HR45@201174|Actinobacteria,4CSZH@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_34	530564.Psta_1475	4.409e-123	414.0	COG1479@1|root,COG1479@2|Bacteria,2J1AJ@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
SRR25158462_k127_1084732_101	1303518.CCALI_01368	2.025e-42	168.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,RE_EcoO109I
SRR25158462_k127_1084732_73	1123023.JIAI01000014_gene3776	1.479e-81	285.0	COG1322@1|root,COG1322@2|Bacteria,2IC5R@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_21	1283299.AUKG01000001_gene3440	1.873e-154	496.0	COG0604@1|root,COG0604@2|Bacteria,2I66C@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
SRR25158462_k127_1084732_10	1116369.KB890024_gene1410	1.145e-209	657.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TXFW@28211|Alphaproteobacteria,43PD9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158462_k127_1084732_95	446470.Snas_4596	1.379e-53	196.0	COG1595@1|root,COG1595@2|Bacteria,2GMPC@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_1084732_130	211114.JOEF01000001_gene7276	3.504e-19	98.0	2A16Z@1|root,339BQ@2|Bacteria,2GVYJ@201174|Actinobacteria,4ED2N@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_148	469383.Cwoe_1427	1.035e-08	68.0	COG4447@1|root,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_105	216594.MMAR_0137	4.783e-37	159.0	COG4430@1|root,COG4430@2|Bacteria,2IQK3@201174|Actinobacteria,23AQD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158462_k127_1084732_100	287.DR97_440	5.395e-45	167.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1YG7R@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158462_k127_1084732_151	1122939.ATUD01000001_gene274	6.84e-05	53.0	2B64F@1|root,31Z1A@2|Bacteria,2HR98@201174|Actinobacteria,4CT5R@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_103	644548.SCNU_13854	6.76e-39	157.0	COG3945@1|root,COG3945@2|Bacteria,2IA3E@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158462_k127_1084732_23	292564.Cyagr_1736	8.609e-150	490.0	COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158462_k127_1084732_147	1463895.JODA01000033_gene3078	4.595e-09	69.0	COG2706@1|root,COG2931@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	AIDA,HemolysinCabind,VCBS
SRR25158462_k127_1084732_113	102129.Lepto7375DRAFT_2637	1.002e-27	130.0	COG2706@1|root,COG5276@1|root,COG2706@2|Bacteria,COG5276@2|Bacteria,1GQNB@1117|Cyanobacteria	1117|Cyanobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,DUF4347,Lactonase
SRR25158462_k127_1084732_153	526225.Gobs_2940	0.000572	52.0	COG3835@1|root,COG3835@2|Bacteria,2GRBZ@201174|Actinobacteria,4EXH6@85013|Frankiales	201174|Actinobacteria	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158462_k127_1084732_138	1121271.AUCM01000011_gene1959	5.217e-13	79.0	COG2362@1|root,COG2362@2|Bacteria,1QH4F@1224|Proteobacteria,2U3TC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
SRR25158462_k127_1084732_149	1242864.D187_002408	3.182e-08	65.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158462_k127_1084732_110	479432.Sros_2145	1.274e-31	130.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,4EJZA@85012|Streptosporangiales	201174|Actinobacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158462_k127_1084732_122	2074.JNYD01000001_gene5816	4.073e-24	108.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4E0E1@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158462_k127_1084732_135	525897.Dbac_1330	1.506e-14	81.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631,Flg_new,GPDPase_memb
SRR25158462_k127_1084732_6	1380390.JIAT01000013_gene2	2.862e-245	765.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4CPGU@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158462_k127_1084732_35	469383.Cwoe_5009	2.212e-122	400.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158462_k127_1084732_128	710111.FraQA3DRAFT_6179	2.98e-20	102.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKUC@201174|Actinobacteria,4EVJ1@85013|Frankiales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,PAS,PAS_4,SpoIIE
SRR25158462_k127_1084732_131	1380390.JIAT01000009_gene732	2.525e-18	98.0	2E5JX@1|root,330B5@2|Bacteria,2HREB@201174|Actinobacteria,4CTCI@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
SRR25158462_k127_1084732_30	469383.Cwoe_2075	8.371e-130	455.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4CPIH@84995|Rubrobacteria	84995|Rubrobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158462_k127_1084732_3	1380390.JIAT01000010_gene4867	2.302e-282	889.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4CP77@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158462_k127_1084732_102	469383.Cwoe_1697	2.386e-39	161.0	COG5607@1|root,COG5607@2|Bacteria,2HQYQ@201174|Actinobacteria,4CSRG@84995|Rubrobacteria	84995|Rubrobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
SRR25158462_k127_1084732_36	645465.ACUR01000699_gene4273	3.05e-120	408.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158462_k127_1084732_74	1283299.AUKG01000001_gene2175	1.044e-80	297.0	COG1929@1|root,COG1929@2|Bacteria,2IE2M@201174|Actinobacteria,4CU5J@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycerate kinase family	-	-	-	-	-	-	-	-	-	-	-	-	Gly_kinase
SRR25158462_k127_1084732_109	1380390.JIAT01000010_gene4090	1.132e-32	137.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_1084732_118	1048339.KB913029_gene2505	5.105e-25	109.0	COG0640@1|root,COG0640@2|Bacteria,2IRF0@201174|Actinobacteria,4EWG5@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158462_k127_1084732_4	1380390.JIAT01000009_gene649	7.988e-280	877.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_1084732_106	237368.SCABRO_01729	5.856e-37	149.0	COG0518@1|root,COG0518@2|Bacteria,2J0QU@203682|Planctomycetes	203682|Planctomycetes	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SRR25158462_k127_1084732_49	1283299.AUKG01000001_gene2461	4.513e-106	350.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CPC2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158462_k127_1084732_9	42256.RradSPS_2749	5.304e-213	678.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPFP@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158462_k127_1084732_68	1380390.JIAT01000014_gene6055	4.978e-89	303.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4CPYI@84995|Rubrobacteria	84995|Rubrobacteria	S	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158462_k127_1084732_8	266117.Rxyl_3196	1.323e-215	676.0	COG0174@1|root,COG0174@2|Bacteria,2GM3K@201174|Actinobacteria,4CPBS@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158462_k127_1084732_7	1380390.JIAT01000010_gene3522	2.51e-225	709.0	COG0531@1|root,COG0531@2|Bacteria,2GIWQ@201174|Actinobacteria,4CRNJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158462_k127_1084732_82	1380390.JIAT01000010_gene3534	7.041e-75	262.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
SRR25158462_k127_1084732_1	211114.JOEF01000003_gene3012	0.0	1127.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158462_k127_1084732_86	1380390.JIAT01000010_gene3532	1.739e-72	252.0	COG2186@1|root,COG2186@2|Bacteria,2HQFA@201174|Actinobacteria,4CQ4K@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158462_k127_1084732_150	1122998.AUHZ01000019_gene1699	2.116e-05	50.0	2E8MQ@1|root,332Z5@2|Bacteria,2ISX4@201174|Actinobacteria	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158462_k127_1084732_32	1380390.JIAT01000011_gene2775	1.225e-124	421.0	COG1463@1|root,COG1463@2|Bacteria,2GMMT@201174|Actinobacteria,4CRZH@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158462_k127_1084732_61	469383.Cwoe_1626	1.456e-94	328.0	COG1463@1|root,COG1463@2|Bacteria,2ICM7@201174|Actinobacteria,4CR1J@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158462_k127_1084732_50	1380390.JIAT01000011_gene2773	1.067e-104	363.0	COG1463@1|root,COG1463@2|Bacteria,2I8TQ@201174|Actinobacteria,4CRI0@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158462_k127_1084732_29	1283299.AUKG01000001_gene2858	5.416e-134	444.0	COG1463@1|root,COG1463@2|Bacteria,2HNKW@201174|Actinobacteria,4CPPQ@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
SRR25158462_k127_1084732_65	469383.Cwoe_1623	6.105e-92	321.0	COG1463@1|root,COG1463@2|Bacteria,2GMHC@201174|Actinobacteria	201174|Actinobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158462_k127_1084732_42	1380390.JIAT01000011_gene2770	8.068e-113	381.0	COG1463@1|root,COG1463@2|Bacteria,2IDGH@201174|Actinobacteria,4CREE@84995|Rubrobacteria	84995|Rubrobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158462_k127_1084732_18	469383.Cwoe_1710	7.393e-161	547.0	COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,2HGJ9@201174|Actinobacteria,4CRYN@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_1084732_143	469383.Cwoe_5920	5.728e-12	76.0	2AW9W@1|root,31N5B@2|Bacteria,2HQT5@201174|Actinobacteria,4CSHX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_89	469383.Cwoe_5921	4.226e-65	231.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CP82@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158462_k127_1084732_136	1283299.AUKG01000001_gene3151	8.17e-14	73.0	COG1826@1|root,COG1826@2|Bacteria,2HPGG@201174|Actinobacteria,4CQUZ@84995|Rubrobacteria	84995|Rubrobacteria	U	mttA/Hcf106 family	-	-	-	-	-	-	-	-	-	-	-	-	MttA_Hcf106
SRR25158462_k127_1084732_127	1380390.JIAT01000009_gene1824	2.817e-21	98.0	2AWH1@1|root,31NDH@2|Bacteria,2HQZP@201174|Actinobacteria,4CST3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_48	35754.JNYJ01000021_gene424	3.512e-107	352.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,4DDJD@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_1084732_59	1380390.JIAT01000009_gene1823	2.685e-97	330.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CQGP@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
SRR25158462_k127_1084732_71	469383.Cwoe_5925	3.476e-84	288.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158462_k127_1084732_66	1380390.JIAT01000009_gene1821	1.249e-90	308.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
SRR25158462_k127_1084732_46	469383.Cwoe_5927	1.215e-108	371.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CQ40@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR25158462_k127_1084732_88	469383.Cwoe_5928	5.403e-66	232.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria,4CQW0@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158462_k127_1084732_117	469383.Cwoe_5929	3.46e-25	110.0	2AWJ7@1|root,31NFU@2|Bacteria,2HR1C@201174|Actinobacteria,4CSVI@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_16	929712.KI912613_gene1100	1.194e-171	556.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CPG9@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158462_k127_1084732_22	469383.Cwoe_5931	2.511e-151	497.0	COG1522@1|root,COG1522@2|Bacteria,2IIXK@201174|Actinobacteria,4CPCF@84995|Rubrobacteria	84995|Rubrobacteria	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
SRR25158462_k127_1084732_28	266117.Rxyl_1976	6.68e-136	440.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4CPCJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158462_k127_1084732_72	1283299.AUKG01000001_gene1784	1.8e-82	282.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4CRAH@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158462_k127_1084732_51	1380390.JIAT01000009_gene1813	4.153e-103	352.0	COG1668@1|root,COG1668@2|Bacteria,2HNDN@201174|Actinobacteria,4CP6Y@84995|Rubrobacteria	84995|Rubrobacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158462_k127_1084732_114	1089552.KI911559_gene628	2.895e-27	119.0	2DP3D@1|root,330CN@2|Bacteria,1NC6N@1224|Proteobacteria,2UGME@28211|Alphaproteobacteria,2JUFC@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_78	264732.Moth_1083	2.627e-79	278.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158462_k127_1084732_38	469383.Cwoe_5936	3.387e-117	416.0	2AU3I@1|root,31JPZ@2|Bacteria,2H277@201174|Actinobacteria,4CQ2S@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_24	469383.Cwoe_5938	1.726e-144	475.0	COG1524@1|root,COG1524@2|Bacteria,2HNGC@201174|Actinobacteria,4CPCH@84995|Rubrobacteria	84995|Rubrobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158462_k127_1084732_13	469383.Cwoe_5940	9.726e-194	617.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CPBA@84995|Rubrobacteria	84995|Rubrobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158462_k127_1084732_52	1283299.AUKG01000001_gene1775	1.226e-102	362.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4CPJD@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158462_k127_1084732_76	469383.Cwoe_5941	5.188e-80	269.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158462_k127_1084732_70	469383.Cwoe_5942	2.266e-85	292.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CPD6@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158462_k127_1084732_58	469383.Cwoe_5943	1.577e-97	324.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CQ24@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158462_k127_1084732_107	469383.Cwoe_5946	1.58e-35	141.0	COG1847@1|root,COG1847@2|Bacteria,2HPE2@201174|Actinobacteria,4CQS4@84995|Rubrobacteria	84995|Rubrobacteria	S	single-stranded nucleic acid binding R3H	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158462_k127_1084732_96	469383.Cwoe_5944	5.564e-53	199.0	COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CQFC@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158462_k127_1084732_77	1283299.AUKG01000001_gene1766	1.892e-79	273.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CPXT@84995|Rubrobacteria	84995|Rubrobacteria	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158462_k127_1084732_115	1380390.JIAT01000009_gene1794	9.329e-26	116.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4CQSS@84995|Rubrobacteria	84995|Rubrobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158462_k127_1084732_111	469383.Cwoe_5949	1.473e-30	124.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4CQCA@84995|Rubrobacteria	84995|Rubrobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158462_k127_1084732_142	1118060.CAGZ01000001_gene219	5.467e-12	70.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4CWG7@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158462_k127_1084732_37	469383.Cwoe_0001	5.428e-118	400.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CPFC@84995|Rubrobacteria	84995|Rubrobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SRR25158462_k127_1084732_33	469383.Cwoe_0002	1.049e-123	412.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CP8Y@84995|Rubrobacteria	84995|Rubrobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158462_k127_1084732_83	1380390.JIAT01000009_gene1789	1.179e-74	264.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CQ4U@84995|Rubrobacteria	84995|Rubrobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
SRR25158462_k127_1084732_134	469383.Cwoe_0004	1.613e-15	89.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158462_k127_1084732_2	469383.Cwoe_0005	0.0	1085.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CP8I@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158462_k127_1084732_5	656024.FsymDg_0011	1.798e-268	850.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4ERIW@85013|Frankiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV,Intein_splicing,LAGLIDADG_3
SRR25158462_k127_1084732_90	1380390.JIAT01000009_gene1786	1.812e-63	226.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CQBX@84995|Rubrobacteria	84995|Rubrobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158462_k127_1084732_75	1380390.JIAT01000009_gene1785	1.997e-80	276.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CQFQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158462_k127_1084732_108	1283299.AUKG01000001_gene1753	1.014e-33	144.0	2AVPF@1|root,31MGI@2|Bacteria,2HE2U@201174|Actinobacteria,4CQ1U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_81	469383.Cwoe_0011	1.269e-75	266.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CR9T@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158462_k127_1084732_84	469383.Cwoe_0012	5.954e-74	256.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158462_k127_1084732_112	1283299.AUKG01000001_gene1750	2.55e-29	122.0	COG1716@1|root,COG1716@2|Bacteria,2HM1E@201174|Actinobacteria,4CQ7B@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158462_k127_1084732_63	469383.Cwoe_0014	1.225e-93	328.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158462_k127_1084732_15	469383.Cwoe_0015	2.124e-174	577.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CPCV@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158462_k127_1084732_31	1380390.JIAT01000009_gene1777	2.729e-127	423.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CP9M@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158462_k127_1084732_25	1380390.JIAT01000009_gene1776	2.507e-143	475.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158462_k127_1084732_53	1380390.JIAT01000009_gene1775	2.173e-102	351.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CPG5@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158462_k127_1084732_126	1115803.HMPREF1129_0682	9.853e-22	101.0	COG1247@1|root,COG1247@2|Bacteria,2ISV7@201174|Actinobacteria,4D5V3@85005|Actinomycetales	201174|Actinobacteria	M	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158462_k127_1084732_67	469383.Cwoe_1767	4.162e-89	302.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158462_k127_1084732_80	469383.Cwoe_2931	3.988e-78	276.0	COG2755@1|root,COG2755@2|Bacteria,2I8JW@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158462_k127_1084732_47	105422.BBPM01000014_gene3249	8.616e-108	357.0	COG1075@1|root,COG1075@2|Bacteria,2GM7V@201174|Actinobacteria,2NFS9@228398|Streptacidiphilus	201174|Actinobacteria	S	Lipase (class 2)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
SRR25158462_k127_1084732_12	1449976.KALB_5959	6.942e-196	618.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4E0Y5@85010|Pseudonocardiales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158462_k127_1084732_19	1283299.AUKG01000002_gene4252	4.85e-160	511.0	COG1018@1|root,COG1018@2|Bacteria,2GJSW@201174|Actinobacteria,4CSBD@84995|Rubrobacteria	84995|Rubrobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158462_k127_1084732_87	1463841.JOIR01000012_gene2165	6.698e-72	248.0	2F8F6@1|root,340TX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_152	388401.RB2150_15830	0.0002689	46.0	COG5416@1|root,COG5416@2|Bacteria,1PP5Z@1224|Proteobacteria,2VCH6@28211|Alphaproteobacteria,3ZHVA@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
SRR25158462_k127_1084732_98	469383.Cwoe_3921	2.946e-47	171.0	COG0234@1|root,COG0234@2|Bacteria,2HR96@201174|Actinobacteria,4CT5M@84995|Rubrobacteria	84995|Rubrobacteria	O	Chaperonin 10 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
SRR25158462_k127_1084732_119	396588.Tgr7_1405	5.505e-25	117.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SC2U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	ycdT	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF,MASE4
SRR25158462_k127_1084732_14	469383.Cwoe_0346	3.819e-180	579.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CPI3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_1084732_43	2002.JOEQ01000022_gene6968	1.187e-112	374.0	COG1595@1|root,COG3631@1|root,COG1595@2|Bacteria,COG3631@2|Bacteria,2GMRK@201174|Actinobacteria,4EJ1A@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158462_k127_1084732_154	1122614.JHZF01000011_gene2176	0.0006358	51.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,2U940@28211|Alphaproteobacteria,2PFR1@252301|Oceanicola	28211|Alphaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158462_k127_1084732_0	1380390.JIAT01000010_gene3508	0.0	1226.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158462_k127_1084732_140	469383.Cwoe_4250	3.97e-12	77.0	290AJ@1|root,2ZN05@2|Bacteria,2HRSY@201174|Actinobacteria,4CTW7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1084732_92	469383.Cwoe_4251	1.001e-54	205.0	COG0389@1|root,COG0389@2|Bacteria,2HPPZ@201174|Actinobacteria,4CR2N@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family	-	-	-	-	-	-	-	-	-	-	-	-	IMS
SRR25158462_k127_1084732_99	469383.Cwoe_3152	4.668e-47	178.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1084732_104	1283299.AUKG01000002_gene5039	3.035e-37	150.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1084732_121	469383.Cwoe_3153	4.032e-24	111.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1084732_54	1283299.AUKG01000002_gene4021	2.233e-102	339.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4CS7T@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158462_k127_1084732_27	877455.Metbo_1301	5.187e-138	452.0	arCOG02685@1|root,arCOG02685@2157|Archaea,2XV10@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0477 Permeases of the major facilitator superfamily	csbC	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158462_k127_1084732_64	1283299.AUKG01000003_gene191	2.499e-93	315.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CRD2@84995|Rubrobacteria	84995|Rubrobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158462_k127_1084732_123	1380390.JIAT01000009_gene1681	5.279e-23	108.0	2BJCF@1|root,32DNI@2|Bacteria,2HQBT@201174|Actinobacteria,4CRW5@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158462_k127_1084732_79	1242864.D187_000821	1.043e-78	273.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
SRR25158462_k127_1084732_146	47763.JNZA01000063_gene5372	2.011e-09	66.0	COG1670@1|root,COG1670@2|Bacteria,2GMDB@201174|Actinobacteria	201174|Actinobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158462_k127_1084732_91	1283299.AUKG01000001_gene1650	4.099e-55	212.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CQ5U@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158462_k127_1084732_40	469383.Cwoe_0096	2.961e-116	402.0	COG1215@1|root,COG1215@2|Bacteria,2GXGY@201174|Actinobacteria,4CS4U@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158462_k127_1084732_39	469383.Cwoe_0095	1.797e-116	401.0	COG0438@1|root,COG0438@2|Bacteria,2GNPG@201174|Actinobacteria,4CRMS@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
SRR25158462_k127_1084732_62	1380390.JIAT01000009_gene1694	4.234e-94	332.0	COG1216@1|root,COG1216@2|Bacteria,2HU9H@201174|Actinobacteria,4CPRC@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158462_k127_1084732_41	469383.Cwoe_0093	8.917e-114	384.0	COG2244@1|root,COG2244@2|Bacteria,2I9QU@201174|Actinobacteria,4CRDA@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158462_k127_1084732_45	1380390.JIAT01000009_gene1700	2.365e-109	372.0	COG3307@1|root,COG3307@2|Bacteria,2IDMZ@201174|Actinobacteria,4CRI9@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158462_k127_1084732_137	929712.KI912613_gene1158	1.144e-13	77.0	COG0823@1|root,COG0823@2|Bacteria,2HNKQ@201174|Actinobacteria,4CPPF@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
SRR25158462_k127_1084732_11	469383.Cwoe_0086	4.148e-208	664.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4CP9E@84995|Rubrobacteria	84995|Rubrobacteria	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158462_k127_1084732_85	1380390.JIAT01000009_gene1710	9.249e-74	255.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4CSIG@84995|Rubrobacteria	84995|Rubrobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158462_k127_1084732_69	469383.Cwoe_0081	1.302e-86	302.0	COG1968@1|root,COG1968@2|Bacteria,2HNYX@201174|Actinobacteria,4CTDI@84995|Rubrobacteria	84995|Rubrobacteria	V	Bacitracin resistance protein BacA	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158462_k127_1084732_55	1283299.AUKG01000001_gene1683	7.335e-101	352.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CP9S@84995|Rubrobacteria	84995|Rubrobacteria	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158462_k127_1084732_26	469383.Cwoe_0018	3.629e-138	455.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158462_k127_1084732_132	521011.Mpal_1345	1.138e-16	95.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158462_k127_1084991_2	1283299.AUKG01000001_gene1742	7.697e-09	63.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158462_k127_1084991_1	521011.Mpal_0423	1.14e-18	102.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
SRR25158462_k127_1084991_0	469383.Cwoe_5349	1.988e-21	111.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF11,DUF5122,SGL
SRR25158462_k127_1114811_20	469383.Cwoe_2985	1.927e-60	212.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_1114811_5	469383.Cwoe_0897	3.471e-148	479.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4CSZZ@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158462_k127_1114811_12	1380390.JIAT01000016_gene5622	2.869e-93	319.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4CPJK@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158462_k127_1114811_11	656024.FsymDg_0507	5.763e-107	354.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ERP0@85013|Frankiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
SRR25158462_k127_1114811_18	469383.Cwoe_0206	1.437e-66	242.0	COG3527@1|root,COG3527@2|Bacteria,2IBRH@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the alpha-acetolactate decarboxylase family	budA	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
SRR25158462_k127_1114811_14	1380390.JIAT01000009_gene815	3.651e-89	315.0	2AXGW@1|root,31PGJ@2|Bacteria,2HNNC@201174|Actinobacteria,4CPSP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1114811_3	1283299.AUKG01000003_gene500	2.514e-154	511.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158462_k127_1114811_24	469383.Cwoe_5292	3.377e-28	120.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4CQFN@84995|Rubrobacteria	84995|Rubrobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158462_k127_1114811_16	1380390.JIAT01000009_gene811	1.759e-82	281.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158462_k127_1114811_26	1122921.KB898194_gene882	2.356e-06	60.0	COG2199@1|root,COG2199@2|Bacteria,1VTBQ@1239|Firmicutes,4HNEQ@91061|Bacilli,274C8@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
SRR25158462_k127_1114811_19	469383.Cwoe_5847	8.431e-64	228.0	COG0789@1|root,COG0789@2|Bacteria,2HSQA@201174|Actinobacteria,4CS71@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158462_k127_1114811_1	1229203.KI301992_gene71	7.369e-184	601.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_1114811_23	543632.JOJL01000006_gene9734	1.737e-28	121.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158462_k127_1114811_7	298654.FraEuI1c_6876	9.254e-131	431.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4ERII@85013|Frankiales	201174|Actinobacteria	E	Belongs to the aspartokinase family	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158462_k127_1114811_2	469383.Cwoe_5289	7.889e-158	503.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CQ0I@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158462_k127_1114811_22	469383.Cwoe_2623	1.254e-30	139.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07716	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	CBS,GGDEF,HisKA,SpoIIE
SRR25158462_k127_1114811_4	469383.Cwoe_2622	5.791e-152	495.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CS0G@84995|Rubrobacteria	84995|Rubrobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SRR25158462_k127_1114811_17	666685.R2APBS1_2144	1.114e-78	278.0	COG0475@1|root,COG0475@2|Bacteria,1MVGV@1224|Proteobacteria,1S1ET@1236|Gammaproteobacteria,1X3J6@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158462_k127_1114811_6	469383.Cwoe_5286	8.372e-134	433.0	COG2048@1|root,COG2048@2|Bacteria,2H014@201174|Actinobacteria,4CPAS@84995|Rubrobacteria	84995|Rubrobacteria	C	Cysteine-rich domain	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	CCG
SRR25158462_k127_1114811_8	1283299.AUKG01000003_gene514	5.477e-125	411.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CPGQ@84995|Rubrobacteria	84995|Rubrobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158462_k127_1114811_0	469383.Cwoe_5284	1.271e-261	816.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CP7M@84995|Rubrobacteria	84995|Rubrobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158462_k127_1114811_10	469383.Cwoe_1890	5.007e-107	359.0	COG1363@1|root,COG1363@2|Bacteria,2I6I7@201174|Actinobacteria	201174|Actinobacteria	G	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SRR25158462_k127_1114811_13	469383.Cwoe_5283	2.311e-90	316.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4CPHM@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158462_k127_1114811_21	1283299.AUKG01000001_gene1940	1.58e-49	190.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158462_k127_1114811_9	33876.JNXY01000006_gene944	7.983e-119	397.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4D9XT@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158462_k127_1114811_25	362242.MUL_3629	4.885e-25	112.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,23511@1762|Mycobacteriaceae	201174|Actinobacteria	L	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158462_k127_1114811_15	43354.JOIJ01000033_gene2377	3.429e-86	291.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4DY8C@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158462_k127_1121117_31	670487.Ocepr_1815	5.338e-48	177.0	COG3288@1|root,COG3288@2|Bacteria,1WIIT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	NAD NADP transhydrogenase alpha subunit	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158462_k127_1121117_36	1137269.AZWL01000002_gene6540	1.077e-30	131.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria	201174|Actinobacteria	C	NADP transhydrogenase	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158462_k127_1121117_5	1123024.AUII01000003_gene3540	3.266e-157	509.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158462_k127_1121117_30	1380390.JIAT01000009_gene2098	2.493e-48	182.0	COG2866@1|root,COG2866@2|Bacteria,2HPMB@201174|Actinobacteria,4CQZA@84995|Rubrobacteria	84995|Rubrobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158462_k127_1121117_18	1380390.JIAT01000009_gene479	6.789e-110	366.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4CPQ7@84995|Rubrobacteria	84995|Rubrobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
SRR25158462_k127_1121117_21	1380356.JNIK01000004_gene24	9.635e-100	343.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4ERND@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
SRR25158462_k127_1121117_4	402881.Plav_1144	3.066e-159	509.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,2U0RR@28211|Alphaproteobacteria,1JQ16@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Porphyromonas-type peptidyl-arginine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
SRR25158462_k127_1121117_11	469383.Cwoe_4218	2.101e-140	458.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria,4CRMX@84995|Rubrobacteria	84995|Rubrobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158462_k127_1121117_23	1120936.KB907209_gene1393	1.4e-85	295.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4EGV0@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158462_k127_1121117_13	58123.JOFJ01000034_gene44	1.629e-125	438.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria	201174|Actinobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_8
SRR25158462_k127_1121117_1	469383.Cwoe_4688	1.976e-175	554.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4CP7Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158462_k127_1121117_25	561175.KB894098_gene5223	5.619e-77	267.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4EH4Z@85012|Streptosporangiales	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158462_k127_1121117_34	469383.Cwoe_3152	4.682e-34	143.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1121117_40	1206744.BAGL01000029_gene7268	1.856e-15	87.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria,4G2GW@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1121117_24	469383.Cwoe_5841	3.824e-81	282.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB,cNMP_binding
SRR25158462_k127_1121117_0	469383.Cwoe_4683	4.154e-193	606.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158462_k127_1121117_9	1283299.AUKG01000002_gene3795	2.224e-146	473.0	COG2805@1|root,COG2805@2|Bacteria,2HPWY@201174|Actinobacteria,4CP76@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158462_k127_1121117_3	1283299.AUKG01000001_gene3194	1.992e-165	552.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4CS5C@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
SRR25158462_k127_1121117_8	1283299.AUKG01000004_gene962	6.987e-149	479.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158462_k127_1121117_14	1380390.JIAT01000017_gene5296	8.598e-125	411.0	COG1459@1|root,COG1459@2|Bacteria,2GQW0@201174|Actinobacteria,4CPUI@84995|Rubrobacteria	84995|Rubrobacteria	NU	COG COG1459 Type II secretory pathway component PulF Cell motility and secretion Intracellular trafficking and secretion	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SRR25158462_k127_1121117_42	929712.KI912613_gene3437	7.95e-14	77.0	COG2165@1|root,COG2165@2|Bacteria,2GTN8@201174|Actinobacteria,4CQSF@84995|Rubrobacteria	84995|Rubrobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158462_k127_1121117_46	66429.JOFL01000008_gene986	1.536e-07	65.0	COG0823@1|root,COG0823@2|Bacteria,2IC0F@201174|Actinobacteria	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158462_k127_1121117_43	2045.KR76_22095	1.532e-10	75.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,2HQ9W@201174|Actinobacteria,4DRST@85009|Propionibacteriales	201174|Actinobacteria	MO	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1121117_29	1380390.JIAT01000017_gene5281	1.212e-64	229.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,4CQAS@84995|Rubrobacteria	84995|Rubrobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SRR25158462_k127_1121117_28	1380390.JIAT01000017_gene5280	1.351e-72	259.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria,4CQH2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158462_k127_1121117_37	1283299.AUKG01000004_gene946	1.148e-30	135.0	COG3166@1|root,COG3166@2|Bacteria,2HPHC@201174|Actinobacteria,4CQVM@84995|Rubrobacteria	84995|Rubrobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1121117_35	1380390.JIAT01000017_gene5278	4.534e-32	139.0	2AVF2@1|root,31M71@2|Bacteria,2HPWF@201174|Actinobacteria,4CRB2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	T2SSM
SRR25158462_k127_1121117_45	1283299.AUKG01000004_gene944	1.018e-08	67.0	2B0FJ@1|root,31ST2@2|Bacteria,2HQ6F@201174|Actinobacteria,4CRPF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1121117_32	469383.Cwoe_4680	6.466e-47	177.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria,4CQEM@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158462_k127_1121117_33	1380390.JIAT01000009_gene421	1.196e-44	183.0	2ATZV@1|root,31JJQ@2|Bacteria,2HNRB@201174|Actinobacteria,4CPYQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1121117_16	469383.Cwoe_4670	7.261e-122	416.0	COG0003@1|root,COG0003@2|Bacteria,2HG29@201174|Actinobacteria,4CTSC@84995|Rubrobacteria	84995|Rubrobacteria	D	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158462_k127_1121117_26	469383.Cwoe_4669	1.18e-76	273.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4CPXW@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158462_k127_1121117_15	1380390.JIAT01000009_gene416	4.156e-122	403.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CPVA@84995|Rubrobacteria	84995|Rubrobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158462_k127_1121117_7	1380390.JIAT01000009_gene415	4.685e-152	499.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CRHI@84995|Rubrobacteria	84995|Rubrobacteria	D	Tubulin/FtsZ family, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsZ_C,Tubulin
SRR25158462_k127_1121117_6	469383.Cwoe_4666	4.081e-152	505.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CPY9@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158462_k127_1121117_22	469383.Cwoe_4672	2.339e-99	336.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4CT2V@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylate cyclase regulatory domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
SRR25158462_k127_1121117_19	469383.Cwoe_4655	1.486e-109	362.0	COG0500@1|root,COG2226@2|Bacteria,2HPV9@201174|Actinobacteria,4CR9D@84995|Rubrobacteria	84995|Rubrobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158462_k127_1121117_44	1190606.AJYG01000071_gene209	2.816e-09	68.0	COG5061@1|root,32WUZ@2|Bacteria,1R35P@1224|Proteobacteria,1T63Q@1236|Gammaproteobacteria,1XZA6@135623|Vibrionales	135623|Vibrionales	OU	protein folding in endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1121117_38	234621.RER_30860	3.092e-25	113.0	COG2522@1|root,COG2522@2|Bacteria,2IIBQ@201174|Actinobacteria,4G0Q9@85025|Nocardiaceae	201174|Actinobacteria	O	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1121117_12	469383.Cwoe_4654	1.894e-132	427.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4CP67@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158462_k127_1121117_20	469383.Cwoe_4653	3.439e-100	353.0	COG1543@1|root,COG1543@2|Bacteria,2GKTI@201174|Actinobacteria,4CRV4@84995|Rubrobacteria	84995|Rubrobacteria	G	Domain of unknown function (DUF1957)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1957,Glyco_hydro_57
SRR25158462_k127_1121117_2	469383.Cwoe_4652	5.03e-173	575.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CQI2@84995|Rubrobacteria	84995|Rubrobacteria	G	Starch synthase catalytic domain	-	-	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_1121117_48	1114922.CIFAM_10_01055	6.541e-06	53.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,1SGD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	ahdIC	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_1121117_27	1380390.JIAT01000009_gene397	2.944e-76	261.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CR4C@84995|Rubrobacteria	84995|Rubrobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158462_k127_1121117_10	1283299.AUKG01000002_gene3829	2.712e-141	461.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CQB3@84995|Rubrobacteria	84995|Rubrobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158462_k127_1121117_47	67332.FM21_31125	2.15e-06	58.0	COG3861@1|root,COG3861@2|Bacteria,2IKWD@201174|Actinobacteria	201174|Actinobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158462_k127_1121117_17	1288484.APCS01000023_gene464	1.091e-113	371.0	COG1012@1|root,COG1012@2|Bacteria,1WIGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158462_k127_1165808_0	1283299.AUKG01000001_gene3191	9.007e-256	799.0	COG0519@1|root,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CPPY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158462_k127_1165808_6	469383.Cwoe_1874	5.776e-199	626.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CP9K@84995|Rubrobacteria	84995|Rubrobacteria	F	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158462_k127_1165808_20	469383.Cwoe_1873	2.394e-106	354.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CQ17@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158462_k127_1165808_29	469383.Cwoe_1872	5.152e-71	263.0	COG1686@1|root,COG1686@2|Bacteria,2GJ7C@201174|Actinobacteria,4CP6F@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158462_k127_1165808_53	1216932.CM240_2104	0.0002039	48.0	COG1388@1|root,COG4926@1|root,COG1388@2|Bacteria,COG4926@2|Bacteria,1UKTF@1239|Firmicutes,24M67@186801|Clostridia,36V4V@31979|Clostridiaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158462_k127_1165808_28	1283299.AUKG01000001_gene3186	6.424e-76	264.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CQ00@84995|Rubrobacteria	84995|Rubrobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158462_k127_1165808_47	469383.Cwoe_1870	3.87e-24	105.0	COG0776@1|root,COG0776@2|Bacteria,2HN5N@201174|Actinobacteria,4CQJV@84995|Rubrobacteria	84995|Rubrobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158462_k127_1165808_25	429009.Adeg_0661	5.109e-87	306.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158462_k127_1165808_16	1229780.BN381_90073	2.12e-123	415.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158462_k127_1165808_31	552811.Dehly_0091	2.448e-64	237.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,34CPI@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158462_k127_1165808_35	1283299.AUKG01000001_gene3182	1.758e-53	204.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CQ3I@84995|Rubrobacteria	84995|Rubrobacteria	F	Ham1 family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158462_k127_1165808_22	469383.Cwoe_1866	6.671e-102	336.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158462_k127_1165808_41	1283299.AUKG01000002_gene4426	4.271e-40	156.0	COG2197@1|root,COG2197@2|Bacteria,2HFRV@201174|Actinobacteria,4CSAR@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158462_k127_1165808_3	1380390.JIAT01000010_gene4024	2.183e-216	676.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CP66@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1165808_11	1283299.AUKG01000002_gene4486	2.53e-154	495.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CPIW@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158462_k127_1165808_2	946235.CAER01000008_gene395	1.518e-229	734.0	COG4993@1|root,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli	91061|Bacilli	CG	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
SRR25158462_k127_1165808_26	469383.Cwoe_1863	2.813e-85	295.0	COG0438@1|root,COG0438@2|Bacteria,2I8DC@201174|Actinobacteria,4CR51@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158462_k127_1165808_10	1122939.ATUD01000002_gene1263	2.106e-154	507.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4CPRT@84995|Rubrobacteria	84995|Rubrobacteria	H	Glucose inhibited division protein A	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158462_k127_1165808_5	469383.Cwoe_1857	6.544e-210	671.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158462_k127_1165808_4	469383.Cwoe_1856	3.54e-212	676.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158462_k127_1165808_19	469383.Cwoe_1855	1.635e-108	354.0	COG4293@1|root,COG4293@2|Bacteria,2IG98@201174|Actinobacteria,4CQEX@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158462_k127_1165808_49	1380390.JIAT01000014_gene6121	1.863e-15	82.0	2BCFA@1|root,3260X@2|Bacteria,2HBC1@201174|Actinobacteria,4CT3V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158462_k127_1165808_44	469383.Cwoe_1850	2.935e-35	140.0	COG1310@1|root,COG1310@2|Bacteria,2IFB5@201174|Actinobacteria,4CQGR@84995|Rubrobacteria	84995|Rubrobacteria	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158462_k127_1165808_8	469383.Cwoe_1846	3.54e-164	521.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPXX@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158462_k127_1165808_36	42256.RradSPS_2522	1.016e-52	197.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CQ6I@84995|Rubrobacteria	84995|Rubrobacteria	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158462_k127_1165808_39	1380347.JNII01000005_gene3720	1.285e-42	166.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria	201174|Actinobacteria	E	amino acid ABC transporter	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,DUF2808,SBP_bac_3
SRR25158462_k127_1165808_23	1232436.CAPF01000008_gene1784	4.358e-90	316.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CUNV@84998|Coriobacteriia	84998|Coriobacteriia	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158462_k127_1165808_45	469383.Cwoe_1845	6.824e-34	132.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CTFG@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158462_k127_1165808_9	1380390.JIAT01000014_gene6127	5.193e-157	504.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158462_k127_1165808_21	671143.DAMO_1338	4.642e-104	346.0	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1,DDE_Tnp_IS240
SRR25158462_k127_1165808_14	1254432.SCE1572_52550	1.475e-133	434.0	COG1192@1|root,COG1192@2|Bacteria,1QJU3@1224|Proteobacteria	1224|Proteobacteria	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,TIR_2
SRR25158462_k127_1165808_51	261292.Nit79A3_2960	2.439e-09	60.0	2EUJ6@1|root,33N15@2|Bacteria,1NANE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1165808_52	1280947.HY30_19165	1.114e-07	60.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,2UGRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158462_k127_1165808_24	1121422.AUMW01000007_gene3132	2.844e-89	303.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,24ACH@186801|Clostridia,260X8@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158462_k127_1165808_34	1380390.JIAT01000014_gene6128	1.575e-56	207.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4CSHA@84995|Rubrobacteria	84995|Rubrobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158462_k127_1165808_27	1283299.AUKG01000001_gene3145	2.931e-80	297.0	COG2197@1|root,COG2197@2|Bacteria,2HFRK@201174|Actinobacteria,4CS96@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158462_k127_1165808_32	469383.Cwoe_5399	8.865e-58	204.0	COG1959@1|root,COG1959@2|Bacteria,2HQP9@201174|Actinobacteria,4CSAH@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158462_k127_1165808_17	469383.Cwoe_5398	3.877e-121	402.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CPSF@84995|Rubrobacteria	84995|Rubrobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158462_k127_1165808_12	765420.OSCT_1487	1.25e-138	460.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,3766K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158462_k127_1165808_38	1380390.JIAT01000009_gene525	1.169e-46	171.0	COG0822@1|root,COG0822@2|Bacteria,2HNZE@201174|Actinobacteria,4CQ8X@84995|Rubrobacteria	84995|Rubrobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158462_k127_1165808_30	298654.FraEuI1c_5611	1.113e-65	241.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4EVP5@85013|Frankiales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158462_k127_1165808_40	1380390.JIAT01000009_gene518	2.267e-40	152.0	COG2146@1|root,COG2146@2|Bacteria,2HPIQ@201174|Actinobacteria,4CQW9@84995|Rubrobacteria	84995|Rubrobacteria	P	Rieske 2Fe-2S iron-sulphur domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158462_k127_1165808_1	469383.Cwoe_5394	9.33e-256	799.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158462_k127_1165808_15	469383.Cwoe_5393	4.237e-133	434.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158462_k127_1165808_18	469383.Cwoe_5770	2.55e-112	382.0	COG0348@1|root,COG0348@2|Bacteria,2I6I5@201174|Actinobacteria,4CS5U@84995|Rubrobacteria	84995|Rubrobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1165808_48	1380390.JIAT01000014_gene6135	3.307e-17	94.0	2E7T5@1|root,3328A@2|Bacteria,2HRAP@201174|Actinobacteria,4CT7M@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1165808_46	1078020.KEK_13943	1.645e-24	116.0	COG2032@1|root,COG2032@2|Bacteria	2|Bacteria	P	superoxide dismutase activity	sodC	-	1.15.1.1	ko:K02674,ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	-	-	-	Sod_Cu
SRR25158462_k127_1165808_42	469383.Cwoe_1839	4.421e-40	160.0	COG0526@1|root,COG0526@2|Bacteria,2GKDT@201174|Actinobacteria,4CRTZ@84995|Rubrobacteria	84995|Rubrobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158462_k127_1165808_37	469383.Cwoe_0387	2.086e-51	187.0	COG0346@1|root,COG0346@2|Bacteria,2HRG5@201174|Actinobacteria,4CTF6@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_1165808_13	469383.Cwoe_1837	1.938e-134	458.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158462_k127_1165808_7	469383.Cwoe_1834	1.647e-188	599.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CPIV@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158462_k127_1165808_43	469383.Cwoe_1036	2.09e-38	145.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,4CTD9@84995|Rubrobacteria	84995|Rubrobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158462_k127_1241659_0	1137269.AZWL01000019_gene4132	5.782e-93	319.0	COG0683@1|root,COG0683@2|Bacteria,2I9XT@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158462_k127_1241659_1	1380391.JIAS01000017_gene735	0.0001024	46.0	COG4177@1|root,COG4177@2|Bacteria,1PA94@1224|Proteobacteria,2TSNM@28211|Alphaproteobacteria,2JRB3@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
SRR25158462_k127_1242106_6	469383.Cwoe_3158	2.666e-101	340.0	COG1737@1|root,COG1737@2|Bacteria,2HGPB@201174|Actinobacteria,4CPA9@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158462_k127_1242106_4	469383.Cwoe_3160	8.643e-135	437.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CPM6@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158462_k127_1242106_9	469383.Cwoe_3161	6.401e-62	218.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CQEG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158462_k127_1242106_5	316274.Haur_3114	4.265e-116	392.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,376Y0@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158462_k127_1242106_13	1283299.AUKG01000002_gene3646	3.34e-15	81.0	2BFTB@1|root,329N8@2|Bacteria,2HPDP@201174|Actinobacteria,4CQRK@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1242106_7	1283299.AUKG01000002_gene5247	1.182e-93	317.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CPAM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158462_k127_1242106_11	469383.Cwoe_3179	4.415e-49	182.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CQCR@84995|Rubrobacteria	84995|Rubrobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158462_k127_1242106_10	1380390.JIAT01000010_gene4896	1.19e-57	216.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CQA9@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158462_k127_1242106_3	469383.Cwoe_3181	3.786e-139	454.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CP8G@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158462_k127_1242106_8	469383.Cwoe_3182	7.067e-68	234.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158462_k127_1242106_1	1380390.JIAT01000010_gene4890	6.41e-261	835.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158462_k127_1242106_12	1283299.AUKG01000002_gene5234	9.092e-25	105.0	2AUQD@1|root,31KDC@2|Bacteria,2HP8X@201174|Actinobacteria,4CQM7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1242106_2	1122939.ATUD01000005_gene2688	8.359e-161	537.0	COG0608@1|root,COG0608@2|Bacteria,2IK2U@201174|Actinobacteria,4CPI9@84995|Rubrobacteria	84995|Rubrobacteria	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158462_k127_1242106_0	1283299.AUKG01000002_gene5232	0.0	1016.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158462_k127_1292836_0	1121127.JAFA01000031_gene4654	2.161e-209	660.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2VJ40@28216|Betaproteobacteria,1K4VW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158462_k127_1292836_4	404589.Anae109_0627	6.163e-15	78.0	2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158462_k127_1292836_3	864051.BurJ1DRAFT_1863	7.792e-26	107.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
SRR25158462_k127_1292836_2	1458427.BAWN01000024_gene1505	4.488e-29	117.0	COG1598@1|root,COG1598@2|Bacteria,1NBIX@1224|Proteobacteria,2WBYU@28216|Betaproteobacteria,4AIJW@80864|Comamonadaceae	28216|Betaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158462_k127_1292836_1	1118235.CAJH01000023_gene1546	9.601e-170	547.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1X8XV@135614|Xanthomonadales	135614|Xanthomonadales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158462_k127_1333618_0	292459.STH2084	1.106e-107	364.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR25158462_k127_1351672_9	1408427.JADB01000006_gene134	2.593e-18	88.0	2DTS4@1|root,33MFD@2|Bacteria,1PTGB@1224|Proteobacteria,2V5BU@28211|Alphaproteobacteria,48UEV@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_5	748671.LCRIS_00440	5.181e-24	102.0	2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_7	498761.HM1_3148	4.848e-19	88.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_6	1173021.ALWA01000027_gene2631	1.073e-23	101.0	2EK6X@1|root,33DXA@2|Bacteria,1GFHH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_8	1205908.AKXW01000016_gene2640	7.161e-19	87.0	2DMHR@1|root,32RMI@2|Bacteria,1QK1W@1224|Proteobacteria,1TI4F@1236|Gammaproteobacteria,1XYCQ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_3	1408445.JHXP01000064_gene3062	9.126e-26	108.0	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,1SDU5@1236|Gammaproteobacteria,1JG7K@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_18	568703.LGG_00821	8.247e-06	51.0	292C0@1|root,2ZPWE@2|Bacteria,1W1IU@1239|Firmicutes,4I189@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_4	500640.CIT292_08808	4.519e-25	106.0	2AHMX@1|root,317ZV@2|Bacteria,1PZIR@1224|Proteobacteria,1SU9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_11	1430440.MGMSRv2_1983	7.538e-15	76.0	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria,2UJNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_2	272624.lpg2751	8.541e-27	113.0	2DTV2@1|root,33MS7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_1	471874.PROSTU_00109	1.179e-37	141.0	29XIP@1|root,30J9M@2|Bacteria,1QGXJ@1224|Proteobacteria,1TEDR@1236|Gammaproteobacteria,3ZADK@586|Providencia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_10	471874.PROSTU_00109	4.415e-15	75.0	29XIP@1|root,30J9M@2|Bacteria,1QGXJ@1224|Proteobacteria,1TEDR@1236|Gammaproteobacteria,3ZADK@586|Providencia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1351672_0	862965.PARA_14000	1.595e-66	227.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,1S5B2@1236|Gammaproteobacteria,1Y8GF@135625|Pasteurellales	135625|Pasteurellales	S	by Glimmer3	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1363914_4	696747.NIES39_Q02600	1.439e-101	342.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158462_k127_1363914_6	1463858.JOHR01000019_gene4365	1.836e-98	332.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158462_k127_1363914_0	469383.Cwoe_1723	6.51e-165	560.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CRWU@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPase (P-type)	-	-	3.6.3.8	ko:K01537,ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.2,3.A.3.23	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158462_k127_1363914_5	1032480.MLP_02750	5.585e-99	340.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4DPFA@85009|Propionibacteriales	201174|Actinobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2
SRR25158462_k127_1363914_7	1380390.JIAT01000009_gene1264	2.588e-73	257.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4CQH3@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158462_k127_1363914_3	1122939.ATUD01000004_gene3912	7.89e-117	400.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4CR9F@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158462_k127_1363914_15	670487.Ocepr_1188	1.197e-12	74.0	COG2050@1|root,COG2050@2|Bacteria,1WJS6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158462_k127_1363914_1	391625.PPSIR1_41589	1.547e-135	437.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158462_k127_1363914_2	1051632.TPY_1835	3.477e-127	417.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2499D@186801|Clostridia,3WDUV@538999|Clostridiales incertae sedis	186801|Clostridia	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158462_k127_1363914_14	243164.DET1448	2.502e-15	78.0	29WVC@1|root,30IH0@2|Bacteria,2G9KW@200795|Chloroflexi,34DPM@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1363914_9	526225.Gobs_3941	5.003e-56	201.0	COG1595@1|root,COG1595@2|Bacteria,2IMV5@201174|Actinobacteria,4EX78@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158462_k127_1363914_13	1179773.BN6_36160	1.565e-21	104.0	COG5662@1|root,COG5662@2|Bacteria,2INVC@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158462_k127_1363914_11	1137269.AZWL01000012_gene3017	3.665e-32	140.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158462_k127_1363914_8	1380390.JIAT01000017_gene5246	1.561e-69	241.0	COG0204@1|root,COG0204@2|Bacteria,2IHH7@201174|Actinobacteria,4CPY0@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158462_k127_1363914_12	483219.LILAB_14115	1.805e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,1NKV4@1224|Proteobacteria,42RNI@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158462_k127_1363914_10	42256.RradSPS_2114	8.379e-46	168.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158462_k127_1371988_0	469383.Cwoe_2905	2.33e-267	835.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158462_k127_1371988_8	1283299.AUKG01000001_gene2708	2.043e-43	169.0	COG2949@1|root,COG2949@2|Bacteria,2GWVK@201174|Actinobacteria,4CQSA@84995|Rubrobacteria	84995|Rubrobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158462_k127_1371988_6	469383.Cwoe_1578	6.44e-76	265.0	COG0627@1|root,COG0627@2|Bacteria,2HQW9@201174|Actinobacteria,4CSNZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158462_k127_1371988_4	1380390.JIAT01000010_gene4553	2.838e-102	344.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4CPB1@84995|Rubrobacteria	84995|Rubrobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158462_k127_1371988_1	1380390.JIAT01000016_gene5502	1.227e-216	689.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2GJ75@201174|Actinobacteria,4CPFI@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
SRR25158462_k127_1371988_2	1380390.JIAT01000016_gene5500	1.565e-158	526.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2HF4S@201174|Actinobacteria,4CPSY@84995|Rubrobacteria	84995|Rubrobacteria	ET	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
SRR25158462_k127_1371988_7	1380390.JIAT01000016_gene5499	1.005e-55	199.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,4CQ18@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
SRR25158462_k127_1371988_5	1380390.JIAT01000016_gene5498	1.292e-95	326.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CPKV@84995|Rubrobacteria	84995|Rubrobacteria	P	Putative NAD(P)-binding	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158462_k127_1371988_3	469383.Cwoe_2913	4.829e-135	441.0	COG0446@1|root,COG0446@2|Bacteria,2H2SC@201174|Actinobacteria,4CRSC@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
SRR25158462_k127_1396168_0	1380390.JIAT01000009_gene374	4.882e-203	647.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
SRR25158462_k127_1396168_3	1283299.AUKG01000002_gene3856	3.151e-135	437.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CPAU@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158462_k127_1396168_4	469383.Cwoe_4640	1.906e-133	429.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CPQ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158462_k127_1396168_7	469383.Cwoe_4641	1.508e-64	228.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria,4CQ6D@84995|Rubrobacteria	84995|Rubrobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158462_k127_1396168_6	469383.Cwoe_4644	1.528e-78	272.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CRTI@84995|Rubrobacteria	84995|Rubrobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158462_k127_1396168_2	469383.Cwoe_4643	1.007e-171	546.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPNX@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158462_k127_1396168_5	469383.Cwoe_4642	8.626e-125	415.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CPVK@84995|Rubrobacteria	84995|Rubrobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158462_k127_1396168_9	29306.JOBE01000021_gene462	8.055e-46	173.0	COG2050@1|root,COG2050@2|Bacteria,2IJ48@201174|Actinobacteria	201174|Actinobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158462_k127_1396168_8	929712.KI912613_gene2771	3.82e-52	188.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4CQGV@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158462_k127_1396168_1	243230.DR_A0126	1.178e-201	638.0	COG1012@1|root,COG1012@2|Bacteria,1WIGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158462_k127_1396168_10	1380390.JIAT01000010_gene4843	9.919e-39	153.0	COG0779@1|root,COG0779@2|Bacteria,2HPFT@201174|Actinobacteria,4CQU9@84995|Rubrobacteria	84995|Rubrobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158462_k127_1401278_8	1380390.JIAT01000010_gene3631	8.286e-20	94.0	2B40Q@1|root,31WQZ@2|Bacteria,2HY8X@201174|Actinobacteria,4CQG9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1401278_0	469383.Cwoe_4482	4.978e-313	969.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4CPI8@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158462_k127_1401278_6	1283299.AUKG01000001_gene1940	8.177e-46	177.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158462_k127_1401278_3	1123023.JIAI01000002_gene5884	2.641e-79	274.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4E1KU@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158462_k127_1401278_4	929712.KI912613_gene762	9.11e-65	238.0	COG2085@1|root,COG2085@2|Bacteria,2I8W4@201174|Actinobacteria,4CQDF@84995|Rubrobacteria	84995|Rubrobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158462_k127_1401278_2	469383.Cwoe_4149	8.206e-86	297.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4CPHB@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158462_k127_1401278_7	1380390.JIAT01000010_gene3612	1.258e-44	181.0	COG1920@1|root,COG1920@2|Bacteria,2HNVD@201174|Actinobacteria,4CQ43@84995|Rubrobacteria	84995|Rubrobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158462_k127_1401278_5	469383.Cwoe_4151	4.732e-64	238.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158462_k127_1401278_9	1283299.AUKG01000003_gene393	2.538e-07	57.0	COG3237@1|root,COG3237@2|Bacteria,2HPFB@201174|Actinobacteria,4CQTP@84995|Rubrobacteria	84995|Rubrobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158462_k127_1401278_1	266117.Rxyl_0056	3.906e-149	477.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRR25158462_k127_1423249_47	469383.Cwoe_4583	2.721e-104	350.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CPE0@84995|Rubrobacteria	84995|Rubrobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158462_k127_1423249_99	469383.Cwoe_4582	2.372e-46	171.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CQII@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158462_k127_1423249_149	391037.Sare_3848	0.0007001	53.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4DDIY@85008|Micromonosporales	201174|Actinobacteria	L	competence protein ComEA helix-hairpin-helix repeat protein	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158462_k127_1423249_26	1122939.ATUD01000003_gene3532	1.209e-154	503.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CPTP@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158462_k127_1423249_148	1125971.ASJB01000022_gene6908	0.0001734	48.0	COG0640@1|root,COG0640@2|Bacteria,2IEV0@201174|Actinobacteria,4E462@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_1423249_146	1463861.JNXE01000008_gene9605	9.516e-05	52.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_1423249_120	1121015.N789_00635	1.166e-25	113.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,1SGRZ@1236|Gammaproteobacteria,1X6RX@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158462_k127_1423249_44	469383.Cwoe_2990	2.543e-110	400.0	COG2220@1|root,COG2220@2|Bacteria,2GMFQ@201174|Actinobacteria	201174|Actinobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158462_k127_1423249_38	1125863.JAFN01000001_gene244	9.795e-119	416.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158462_k127_1423249_42	469383.Cwoe_0202	2.82e-112	382.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CPQ8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158462_k127_1423249_49	469383.Cwoe_1695	1.606e-100	335.0	COG0788@1|root,COG0788@2|Bacteria,2GM0G@201174|Actinobacteria,4CR0G@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
SRR25158462_k127_1423249_61	1278073.MYSTI_07213	1.99e-84	304.0	COG2227@1|root,COG2227@2|Bacteria,1QX4V@1224|Proteobacteria,43BXJ@68525|delta/epsilon subdivisions,2X99C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SRR25158462_k127_1423249_118	929712.KI912613_gene413	1.11e-27	118.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
SRR25158462_k127_1423249_43	469383.Cwoe_4554	1.269e-111	370.0	COG3294@1|root,COG3294@2|Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158462_k127_1423249_92	1122939.ATUD01000008_gene2441	1.637e-53	201.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4CSZW@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
SRR25158462_k127_1423249_84	485913.Krac_8201	1.517e-60	220.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
SRR25158462_k127_1423249_121	408672.NBCG_04239	1.462e-25	110.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4DRUV@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158462_k127_1423249_141	1283299.AUKG01000002_gene4022	3.467e-09	63.0	2AXHB@1|root,32I9X@2|Bacteria,2HRFS@201174|Actinobacteria,4CTEM@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_72	1313172.YM304_10970	1.018e-75	263.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158462_k127_1423249_51	1122939.ATUD01000007_gene2049	3.997e-98	328.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CPSW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_1423249_123	1122939.ATUD01000007_gene2054	4.708e-24	104.0	COG0745@1|root,COG0745@2|Bacteria,2HRF4@201174|Actinobacteria,4CTDQ@84995|Rubrobacteria	84995|Rubrobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158462_k127_1423249_37	469383.Cwoe_4492	3.077e-120	394.0	COG0226@1|root,COG0226@2|Bacteria,2H61B@201174|Actinobacteria,4CTXY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	-
SRR25158462_k127_1423249_46	469383.Cwoe_4493	5.097e-105	349.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158462_k127_1423249_33	469383.Cwoe_4494	4.727e-133	437.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4CQ28@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158462_k127_1423249_34	469383.Cwoe_4495	1.02e-128	417.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CP9Q@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158462_k127_1423249_69	1380390.JIAT01000001_gene4997	7.43e-81	279.0	COG0704@1|root,COG0704@2|Bacteria,2HGEG@201174|Actinobacteria,4CPTJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158462_k127_1423249_78	469383.Cwoe_4556	3.173e-64	231.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158462_k127_1423249_4	1380390.JIAT01000001_gene5016	1.295e-285	900.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2GIZG@201174|Actinobacteria,4CPGZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,PHP_C
SRR25158462_k127_1423249_3	1380390.JIAT01000001_gene5041	2.362e-288	910.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4CPPB@84995|Rubrobacteria	84995|Rubrobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158462_k127_1423249_70	469383.Cwoe_2888	2.989e-76	260.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4CPW4@84995|Rubrobacteria	84995|Rubrobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158462_k127_1423249_27	469383.Cwoe_2887	1.86e-154	495.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4CQZ9@84995|Rubrobacteria	84995|Rubrobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158462_k127_1423249_134	1380390.JIAT01000001_gene4995	7.866e-15	78.0	2AUSG@1|root,31KFH@2|Bacteria,2HPAB@201174|Actinobacteria,4CQNM@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_137	469383.Cwoe_4539	8.535e-13	73.0	2BGGW@1|root,32AEX@2|Bacteria,2HPGT@201174|Actinobacteria,4CQV3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158462_k127_1423249_40	469383.Cwoe_4537	1.707e-113	390.0	COG0741@1|root,COG1876@1|root,COG0741@2|Bacteria,COG1876@2|Bacteria,2I4JK@201174|Actinobacteria,4CQYM@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	SLT,VanY
SRR25158462_k127_1423249_102	1097668.BYI23_A008710	1.794e-45	180.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2VS2S@28216|Betaproteobacteria,1KH4H@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRR25158462_k127_1423249_36	479432.Sros_4028	4.268e-124	415.0	COG0492@1|root,COG0664@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,2GK62@201174|Actinobacteria,4EN6B@85012|Streptosporangiales	201174|Actinobacteria	C	Cyclic nucleotide-monophosphate binding domain	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158462_k127_1423249_113	469383.Cwoe_5434	9.894e-30	136.0	COG0662@1|root,COG0662@2|Bacteria,2HRBD@201174|Actinobacteria,4CT8K@84995|Rubrobacteria	84995|Rubrobacteria	G	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_100	1211815.CBYP010000036_gene2241	7.265e-46	170.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,4ESRP@85013|Frankiales	201174|Actinobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158462_k127_1423249_130	469383.Cwoe_1897	1.357e-17	89.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	pbrT	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,Cytochrome_CBB3,FTR1
SRR25158462_k127_1423249_85	66429.JOFL01000020_gene5559	2.617e-59	217.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1,SnoaL_2
SRR25158462_k127_1423249_5	469383.Cwoe_4536	9.746e-254	803.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CPMP@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158462_k127_1423249_45	1380390.JIAT01000015_gene5677	2.666e-107	362.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CQY7@84995|Rubrobacteria	84995|Rubrobacteria	S	P-loop ATPase protein family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_2
SRR25158462_k127_1423249_145	1209984.BN978_06835	5.332e-05	52.0	29HEG@1|root,304BV@2|Bacteria,2II74@201174|Actinobacteria,2398F@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_48	1906.SFRA_18605	7.334e-104	345.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158462_k127_1423249_86	235985.BBPN01000001_gene1080	4.233e-59	224.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,2NJ3P@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158462_k127_1423249_132	1403819.BATR01000066_gene1979	1.707e-16	84.0	COG0346@1|root,COG0346@2|Bacteria,46XHN@74201|Verrucomicrobia,2IVY3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_1423249_29	1001240.GY21_06695	4.804e-141	456.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4FM64@85023|Microbacteriaceae	201174|Actinobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158462_k127_1423249_24	469383.Cwoe_4529	5.395e-155	500.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CPN6@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158462_k127_1423249_53	469383.Cwoe_4528	3.496e-93	314.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CQ0V@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158462_k127_1423249_10	469383.Cwoe_4527	8.814e-207	664.0	COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CR8U@84995|Rubrobacteria	84995|Rubrobacteria	G	BPG-independent PGAM N-terminus (iPGM_N)	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158462_k127_1423249_30	1283299.AUKG01000002_gene4120	1.29e-139	465.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CPB3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158462_k127_1423249_50	469383.Cwoe_4523	2.766e-99	341.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CPGP@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158462_k127_1423249_65	469383.Cwoe_4521	2.527e-82	283.0	COG0639@1|root,COG0639@2|Bacteria,2HNQI@201174|Actinobacteria,4CPX1@84995|Rubrobacteria	84995|Rubrobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158462_k127_1423249_16	469383.Cwoe_4517	1.195e-186	600.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CP8V@84995|Rubrobacteria	84995|Rubrobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158462_k127_1423249_135	929712.KI912613_gene2532	2.482e-14	86.0	COG0489@1|root,COG0489@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CQDP@84995|Rubrobacteria	84995|Rubrobacteria	D	biosynthesis protein	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,Wzz
SRR25158462_k127_1423249_114	469383.Cwoe_4516	2.655e-29	122.0	COG3088@1|root,COG3088@2|Bacteria,2GXH0@201174|Actinobacteria,4CT29@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SRR25158462_k127_1423249_116	1122223.KB890696_gene314	1.039e-28	123.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158462_k127_1423249_104	469383.Cwoe_3656	5.7e-42	164.0	COG0500@1|root,COG2226@2|Bacteria,2IREW@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158462_k127_1423249_94	1440774.Y900_017285	8.945e-52	196.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,2I2RA@201174|Actinobacteria,23FC5@1762|Mycobacteriaceae	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
SRR25158462_k127_1423249_142	1396.DJ87_251	1.565e-07	58.0	COG0640@1|root,COG0640@2|Bacteria,1V384@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158462_k127_1423249_19	1283299.AUKG01000001_gene2083	8.829e-175	583.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_20	1283299.AUKG01000001_gene2083	6.59e-169	565.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_31	1283299.AUKG01000001_gene2083	9.269e-137	471.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_64	1283299.AUKG01000001_gene2260	7.335e-83	287.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4CQZV@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1423249_63	1380390.JIAT01000002_gene6014	2.868e-83	283.0	COG4221@1|root,COG4221@2|Bacteria,2IAVE@201174|Actinobacteria,4CR7Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_1423249_111	1380390.JIAT01000015_gene5796	1.295e-32	130.0	COG2332@1|root,COG2332@2|Bacteria,2HP5E@201174|Actinobacteria,4CQHD@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmE	-	-	-	-	-	-	-	-	-	-	-	-	CcmE
SRR25158462_k127_1423249_8	469383.Cwoe_4478	1.656e-213	689.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria,4CRCE@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158462_k127_1423249_127	1380390.JIAT01000015_gene5799	3.724e-20	91.0	COG1314@1|root,COG1314@2|Bacteria,2HP6M@201174|Actinobacteria,4CQIR@84995|Rubrobacteria	84995|Rubrobacteria	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
SRR25158462_k127_1423249_12	469383.Cwoe_5739	6.439e-201	631.0	COG3239@1|root,COG3239@2|Bacteria,2GIWV@201174|Actinobacteria,4CRJF@84995|Rubrobacteria	84995|Rubrobacteria	CI	Fatty acid desaturase	-	-	1.14.15.3	ko:K00496	ko00071,ko00930,map00071,map00930	-	R01347,R02281,R06945	RC00478	ko00000,ko00001,ko01000	-	-	-	FA_desaturase,Rubredoxin
SRR25158462_k127_1423249_125	469383.Cwoe_5738	5.661e-22	110.0	COG1773@1|root,COG1773@2|Bacteria,2GQUH@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the rubredoxin family	alkG	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
SRR25158462_k127_1423249_80	469383.Cwoe_5737	2.515e-63	227.0	COG1309@1|root,COG1309@2|Bacteria,2GMDA@201174|Actinobacteria,4CT7V@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1423249_108	1445613.JALM01000033_gene5084	5.663e-39	153.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158462_k127_1423249_98	1051632.TPY_1878	1.724e-47	179.0	COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,24HA8@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790,ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158462_k127_1423249_77	1229203.KI301992_gene402	1.078e-65	231.0	COG2808@1|root,COG2808@2|Bacteria,2IG1T@201174|Actinobacteria,3UXAK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRR25158462_k127_1423249_128	1122939.ATUD01000001_gene14	1.933e-18	93.0	2C997@1|root,348SM@2|Bacteria,2GTF7@201174|Actinobacteria,4CQRE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_144	68570.DC74_7928	4.396e-06	60.0	COG2909@1|root,COG2909@2|Bacteria,2GJIA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158462_k127_1423249_133	1121456.ATVA01000012_gene2854	5.373e-15	87.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2M925@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SRR25158462_k127_1423249_89	426355.Mrad2831_6131	5.818e-57	212.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,1JR33@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	integrase domain protein SAM domain protein	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158462_k127_1423249_17	365528.KB891115_gene1633	4e-183	587.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EUJZ@85013|Frankiales	201174|Actinobacteria	C	Evidence 2b Function of strongly homologous gene	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158462_k127_1423249_90	469383.Cwoe_2933	2.512e-54	197.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4CS74@84995|Rubrobacteria	84995|Rubrobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158462_k127_1423249_93	1283299.AUKG01000001_gene3426	1.561e-52	193.0	COG3118@1|root,COG3118@2|Bacteria,2IHQV@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158462_k127_1423249_150	1125718.HMPREF1318_1942	0.0007889	49.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4D3UP@85005|Actinomycetales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1,YHS
SRR25158462_k127_1423249_13	1283299.AUKG01000001_gene3430	8.146e-199	639.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4CR6R@84995|Rubrobacteria	84995|Rubrobacteria	OT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158462_k127_1423249_115	1463879.JOHP01000014_gene2105	2.668e-29	128.0	COG0071@1|root,COG0071@2|Bacteria,2IRG0@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158462_k127_1423249_95	44060.JODL01000018_gene4570	3.026e-50	185.0	2CAW2@1|root,32RS7@2|Bacteria,2IB15@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_82	1246995.AFR_33815	3.354e-62	223.0	COG0702@1|root,COG0702@2|Bacteria,2GKNN@201174|Actinobacteria,4DETW@85008|Micromonosporales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158462_k127_1423249_88	1380390.JIAT01000009_gene618	2.264e-57	209.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CSYW@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158462_k127_1423249_1	1283299.AUKG01000001_gene3424	5.425e-318	985.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CP69@84995|Rubrobacteria	84995|Rubrobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158462_k127_1423249_103	469383.Cwoe_0648	2.656e-42	166.0	COG0576@1|root,COG0576@2|Bacteria,2IKK4@201174|Actinobacteria	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE2	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158462_k127_1423249_39	1283299.AUKG01000001_gene3422	7.078e-115	377.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CRC4@84995|Rubrobacteria	84995|Rubrobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158462_k127_1423249_136	469383.Cwoe_0646	2.51e-13	77.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	cbpM	GO:0003674,GO:0004857,GO:0008150,GO:0030234,GO:0043086,GO:0044092,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K18997	-	-	-	-	ko00000,ko03036	-	-	-	MerR_2
SRR25158462_k127_1423249_62	526225.Gobs_1118	3.702e-84	293.0	COG5502@1|root,COG5502@2|Bacteria,2I9TQ@201174|Actinobacteria,4EUJH@85013|Frankiales	201174|Actinobacteria	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_76	1463885.KL578366_gene2803	1.999e-67	242.0	COG0708@1|root,COG0708@2|Bacteria,2I7M4@201174|Actinobacteria	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158462_k127_1423249_58	1380390.JIAT01000010_gene3495	6.05e-88	295.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CQK7@84995|Rubrobacteria	84995|Rubrobacteria	K	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158462_k127_1423249_67	1210046.B277_13644	8.526e-82	286.0	COG0300@1|root,COG0300@2|Bacteria,2I2VP@201174|Actinobacteria,4FJVE@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_1423249_138	1268303.RHODMAR_2721	9.485e-12	69.0	2AR1Y@1|root,31GAW@2|Bacteria,2HK0E@201174|Actinobacteria,4G7PU@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_124	469383.Cwoe_4684	4.1e-23	105.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CSFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158462_k127_1423249_112	1380390.JIAT01000014_gene6073	1.609e-30	130.0	2B89Y@1|root,321II@2|Bacteria,2HP5D@201174|Actinobacteria,4CQHC@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_97	469383.Cwoe_4244	1.442e-47	177.0	COG2128@1|root,COG2128@2|Bacteria,2HNSY@201174|Actinobacteria,4CQ13@84995|Rubrobacteria	84995|Rubrobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158462_k127_1423249_35	1297581.H919_10508	4.811e-128	426.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,21W1F@150247|Anoxybacillus	91061|Bacilli	E	Glutamine synthetase, catalytic domain	glnA	GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158462_k127_1423249_6	469383.Cwoe_4232	5.305e-245	775.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158462_k127_1423249_41	469383.Cwoe_1770	1.848e-112	379.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRAY@84995|Rubrobacteria	201174|Actinobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158462_k127_1423249_21	469383.Cwoe_4225	3.01e-159	518.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,4CRGY@84995|Rubrobacteria	84995|Rubrobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158462_k127_1423249_73	134676.ACPL_4845	7.003e-72	269.0	COG5635@1|root,COG5635@2|Bacteria,2IE7V@201174|Actinobacteria	201174|Actinobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_14	1122604.JONR01000004_gene867	1.978e-195	616.0	COG1960@1|root,COG1960@2|Bacteria,1NCCF@1224|Proteobacteria,1RSJK@1236|Gammaproteobacteria,1X4QG@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1423249_22	1122604.JONR01000004_gene868	3.584e-159	516.0	COG1960@1|root,COG1960@2|Bacteria,1PUXP@1224|Proteobacteria,1RSAW@1236|Gammaproteobacteria,1X30E@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1423249_55	469383.Cwoe_0197	7.038e-92	320.0	COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,4CS7Q@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158462_k127_1423249_25	1283299.AUKG01000002_gene4076	7.252e-155	500.0	COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria,4CR2A@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158462_k127_1423249_11	469383.Cwoe_0195	4.011e-202	638.0	COG0183@1|root,COG0183@2|Bacteria,2GJI8@201174|Actinobacteria,4CPYE@84995|Rubrobacteria	84995|Rubrobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158462_k127_1423249_75	469383.Cwoe_0194	1.803e-67	236.0	COG1309@1|root,COG1309@2|Bacteria,2GNVS@201174|Actinobacteria,4CTMD@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1423249_131	1283299.AUKG01000002_gene4333	2.964e-17	95.0	2AWUM@1|root,31NRV@2|Bacteria,2HRAH@201174|Actinobacteria,4CT7D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_28	1283299.AUKG01000002_gene4334	3.547e-153	498.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CSIF@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
SRR25158462_k127_1423249_15	469383.Cwoe_4214	1.311e-188	599.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	-	-	6.2.1.18	ko:K15232	ko00720,ko01100,ko01120,ko01200,map00720,map01100,map01120,map01200	M00173	R01322	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2
SRR25158462_k127_1423249_0	469383.Cwoe_4211	1.484e-320	988.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158462_k127_1423249_105	1380356.JNIK01000013_gene4213	7.805e-42	174.0	COG1807@1|root,COG1807@2|Bacteria,2IF7N@201174|Actinobacteria,4ETP1@85013|Frankiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158462_k127_1423249_143	1134912.AJTV01000042_gene3587	2.192e-06	58.0	COG4743@1|root,COG4743@2|Bacteria,1MYY8@1224|Proteobacteria,2UBGH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_101	420662.Mpe_A0735	8.866e-46	180.0	COG1215@1|root,COG1215@2|Bacteria,1R66B@1224|Proteobacteria,2VXK9@28216|Betaproteobacteria,1KMH6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1423249_74	1380390.JIAT01000010_gene4362	1.191e-71	269.0	COG0438@1|root,COG0438@2|Bacteria,2GM53@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_1423249_119	996637.SGM_6719	9.843e-26	123.0	COG0438@1|root,COG0438@2|Bacteria,2IRB6@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4
SRR25158462_k127_1423249_109	1297742.A176_07595	5.161e-33	141.0	COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria,43AJP@68525|delta/epsilon subdivisions,2WSH6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1423249_106	1254432.SCE1572_01615	1.993e-40	173.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WPW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_1423249_122	861299.J421_5775	1.158e-24	122.0	2DSI9@1|root,33G8T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_139	1463854.JOHT01000006_gene6642	7.646e-10	68.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158462_k127_1423249_56	526225.Gobs_0397	1.262e-90	306.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158462_k127_1423249_126	1278073.MYSTI_08084	6.425e-21	108.0	COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria,43AJP@68525|delta/epsilon subdivisions,2WSH6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1423249_107	380358.XALC_2293	3.905e-40	168.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RZYF@1236|Gammaproteobacteria,1X5SN@135614|Xanthomonadales	135614|Xanthomonadales	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158462_k127_1423249_96	526225.Gobs_0407	8.063e-48	187.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
SRR25158462_k127_1423249_32	1173028.ANKO01000159_gene5217	3.241e-134	439.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
SRR25158462_k127_1423249_66	237368.SCABRO_01358	7.538e-82	281.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
SRR25158462_k127_1423249_81	909613.UO65_4276	1.09e-62	232.0	COG2244@1|root,COG2244@2|Bacteria,2GMYJ@201174|Actinobacteria,4E3M8@85010|Pseudonocardiales	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	APH,Polysacc_synt
SRR25158462_k127_1423249_68	1158760.AQXP01000046_gene230	3.265e-81	293.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1WWSV@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
SRR25158462_k127_1423249_117	561175.KB894093_gene2814	1.102e-27	129.0	2DS2E@1|root,33E7M@2|Bacteria,2IHF5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_54	172088.AUGA01000083_gene4385	5.007e-93	320.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2U269@28211|Alphaproteobacteria,3JU3T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_1423249_57	1380390.JIAT01000010_gene4357	9.479e-89	321.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1423249_59	460265.Mnod_6871	7.876e-88	319.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1RFXH@1224|Proteobacteria,2U8WU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_1423249_79	1151119.KB895492_gene1636	5.004e-64	238.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,1WAGQ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_1423249_83	1151119.KB895492_gene1636	5.387e-61	226.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,1WAGQ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_1423249_87	67352.JODS01000004_gene6046	4.399e-59	222.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_1423249_91	1312954.KI914846_gene1736	2.755e-54	204.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,1WAGQ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_1423249_71	28444.JODQ01000004_gene6229	4.163e-76	275.0	COG1215@1|root,COG1215@2|Bacteria,2GP1D@201174|Actinobacteria,4EJ5R@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1423249_18	1283299.AUKG01000002_gene4336	1.287e-182	576.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CPSD@84995|Rubrobacteria	84995|Rubrobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158462_k127_1423249_110	469383.Cwoe_1171	1.209e-32	137.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria,4CQAQ@84995|Rubrobacteria	84995|Rubrobacteria	EH	chorismate binding enzyme	-	-	2.6.1.85,4.1.3.38	ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158462_k127_1423249_7	1144275.COCOR_02572	6.267e-218	697.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,1MVBJ@1224|Proteobacteria,437VJ@68525|delta/epsilon subdivisions,2WYPM@28221|Deltaproteobacteria,2YUBC@29|Myxococcales	28221|Deltaproteobacteria	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85	ko:K01665,ko:K13950	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
SRR25158462_k127_1423249_9	469383.Cwoe_4224	7.444e-210	668.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CP7A@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1423249_129	1380390.JIAT01000010_gene3548	2.427e-18	89.0	2BF3V@1|root,328W1@2|Bacteria,2HPA5@201174|Actinobacteria,4CQNE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_23	1380390.JIAT01000009_gene361	9.362e-158	511.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4CSMA@84995|Rubrobacteria	84995|Rubrobacteria	M	UDP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158462_k127_1423249_52	469383.Cwoe_4212	2.566e-97	320.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CQDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158462_k127_1423249_60	469383.Cwoe_4205	6.151e-85	289.0	2AV8W@1|root,31KZS@2|Bacteria,2HPQ4@201174|Actinobacteria,4CR2W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1423249_2	469383.Cwoe_4193	1.973e-311	965.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4CPAH@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158462_k127_1474249_55	1121946.AUAX01000014_gene1109	1.675e-25	117.0	28K6W@1|root,2Z9V8@2|Bacteria,2GNHU@201174|Actinobacteria,4D8S2@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1474249_46	469383.Cwoe_3166	3.014e-47	180.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1474249_3	469383.Cwoe_5915	2.948e-186	593.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CPAP@84995|Rubrobacteria	84995|Rubrobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158462_k127_1474249_44	469383.Cwoe_3170	4.66e-48	183.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria,4CQKR@84995|Rubrobacteria	84995|Rubrobacteria	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158462_k127_1474249_11	1283299.AUKG01000001_gene1815	1.814e-143	469.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CPNU@84995|Rubrobacteria	84995|Rubrobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158462_k127_1474249_53	1122939.ATUD01000008_gene2354	9.164e-32	135.0	COG2898@1|root,COG2898@2|Bacteria,2I33N@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1474249_49	469383.Cwoe_5913	3.168e-45	172.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CQHN@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158462_k127_1474249_60	42256.RradSPS_0737	3.095e-17	84.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CQW6@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158462_k127_1474249_40	1380390.JIAT01000009_gene1856	1.32e-55	198.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CQAY@84995|Rubrobacteria	84995|Rubrobacteria	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158462_k127_1474249_61	469383.Cwoe_5910	5.36e-16	83.0	COG0360@1|root,COG0360@2|Bacteria,2HPGC@201174|Actinobacteria,4CQUW@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S6	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158462_k127_1474249_2	469383.Cwoe_5909	3.109e-210	663.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4CPJV@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase, family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158462_k127_1474249_4	469383.Cwoe_5908	1.376e-184	586.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4CPFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158462_k127_1474249_16	1380390.JIAT01000009_gene1861	4.531e-112	379.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPH3@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158462_k127_1474249_28	1380390.JIAT01000009_gene1862	1.508e-71	263.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2I53J@201174|Actinobacteria,4CRVJ@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158462_k127_1474249_19	469383.Cwoe_5905	4.376e-102	340.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CU2Q@84995|Rubrobacteria	84995|Rubrobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_1474249_34	1380390.JIAT01000009_gene1866	3.067e-63	235.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4CQGK@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158462_k127_1474249_62	28444.JODQ01000002_gene4195	4.467e-14	84.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4EHA8@85012|Streptosporangiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158462_k127_1474249_54	1380390.JIAT01000011_gene2514	3.364e-30	133.0	2DKYN@1|root,30WXH@2|Bacteria,2HQHS@201174|Actinobacteria,4CS33@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158462_k127_1474249_7	1380390.JIAT01000009_gene1868	1.085e-169	557.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158462_k127_1474249_56	1380390.JIAT01000009_gene1869	5.788e-25	113.0	COG0668@1|root,COG0668@2|Bacteria,2GJ51@201174|Actinobacteria,4CRRK@84995|Rubrobacteria	84995|Rubrobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158462_k127_1474249_59	469383.Cwoe_5895	6.343e-20	99.0	COG1266@1|root,COG1266@2|Bacteria,2HRHJ@201174|Actinobacteria,4CTHE@84995|Rubrobacteria	84995|Rubrobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158462_k127_1474249_45	1283299.AUKG01000001_gene1838	1.266e-47	183.0	COG1376@1|root,COG1376@2|Bacteria,2HNPR@201174|Actinobacteria,4CPVE@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158462_k127_1474249_22	469383.Cwoe_2377	1.251e-97	334.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158462_k127_1474249_43	929712.KI912613_gene559	2.655e-53	201.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4CPYW@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158462_k127_1474249_27	469383.Cwoe_5328	1.018e-71	254.0	COG3132@1|root,COG3132@2|Bacteria,2I5BV@201174|Actinobacteria,4CSYU@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function, DUF480	-	-	-	-	-	-	-	-	-	-	-	-	DUF480
SRR25158462_k127_1474249_26	43759.JNWK01000049_gene7136	1.035e-74	275.0	COG0739@1|root,COG3292@1|root,COG0739@2|Bacteria,COG3292@2|Bacteria,2I4DW@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
SRR25158462_k127_1474249_66	1452536.JARE01000013_gene1663	1.674e-09	62.0	2DR8X@1|root,33AQM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1474249_58	395965.Msil_3484	1.25e-20	96.0	COG4113@1|root,COG4113@2|Bacteria,1NEE2@1224|Proteobacteria,2UJ3R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158462_k127_1474249_47	1283299.AUKG01000001_gene1856	7.315e-47	175.0	2AU40@1|root,31JQJ@2|Bacteria,2HNUU@201174|Actinobacteria,4CQ3A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1474249_18	469383.Cwoe_5885	7.261e-104	361.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CRCP@84995|Rubrobacteria	84995|Rubrobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRR25158462_k127_1474249_17	1449069.JMLO01000037_gene2726	2.073e-104	347.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4FYEC@85025|Nocardiaceae	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158462_k127_1474249_63	313589.JNB_03195	2.262e-10	67.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria,4FH7Y@85021|Intrasporangiaceae	201174|Actinobacteria	OU	COG1585 Membrane protein implicated in regulation of membrane protease activity	nfeD	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158462_k127_1474249_48	469383.Cwoe_5883	1.398e-45	172.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158462_k127_1474249_0	469383.Cwoe_5882	0.0	1096.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4CPIG@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
SRR25158462_k127_1474249_38	1380390.JIAT01000009_gene1898	2.384e-56	211.0	COG0340@1|root,COG0340@2|Bacteria,2HGFP@201174|Actinobacteria,4CQNA@84995|Rubrobacteria	84995|Rubrobacteria	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158462_k127_1474249_5	469383.Cwoe_5880	8.218e-184	588.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GK3B@201174|Actinobacteria,4CPJJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158462_k127_1474249_35	1283299.AUKG01000001_gene1870	1.752e-62	232.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4CQ8E@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158462_k127_1474249_12	1122939.ATUD01000015_gene1015	7.039e-137	448.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CPKE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158462_k127_1474249_20	469383.Cwoe_5876	4.647e-102	337.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria,4CSM2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SRR25158462_k127_1474249_32	469383.Cwoe_5875	1.051e-65	232.0	COG2386@1|root,COG2386@2|Bacteria,2GUCP@201174|Actinobacteria,4CQ9M@84995|Rubrobacteria	84995|Rubrobacteria	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SRR25158462_k127_1474249_33	1380390.JIAT01000009_gene1907	2.831e-65	230.0	COG1131@1|root,COG1131@2|Bacteria,2H5DY@201174|Actinobacteria,4CSCC@84995|Rubrobacteria	84995|Rubrobacteria	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SRR25158462_k127_1474249_65	66874.JOFS01000058_gene1480	7.226e-10	71.0	COG1357@1|root,COG1357@2|Bacteria,2IB55@201174|Actinobacteria	201174|Actinobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158462_k127_1474249_64	266117.Rxyl_2044	5.457e-10	72.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4CQR5@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158462_k127_1474249_8	1283299.AUKG01000001_gene1885	7.27e-152	497.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158462_k127_1474249_13	246194.CHY_2201	2.555e-135	445.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,42FF6@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158462_k127_1474249_30	1283299.AUKG01000001_gene1889	4.347e-68	243.0	COG3872@1|root,COG3872@2|Bacteria,2HQG9@201174|Actinobacteria,4CS1C@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158462_k127_1474249_37	469383.Cwoe_5865	3.121e-57	209.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158462_k127_1474249_67	1380390.JIAT01000009_gene1926	2.079e-09	68.0	2AVH0@1|root,31M9B@2|Bacteria,2HPFP@201174|Actinobacteria,4CQTY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1474249_31	42256.RradSPS_3150	3.195e-67	234.0	COG0500@1|root,COG2226@2|Bacteria,2IBEJ@201174|Actinobacteria	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR25158462_k127_1474249_6	1896.JOAU01000017_gene2970	4.487e-181	596.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria	201174|Actinobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158462_k127_1474249_51	1385518.N798_00815	3.898e-35	152.0	COG0300@1|root,COG3832@1|root,COG0300@2|Bacteria,COG3832@2|Bacteria,2IKZ7@201174|Actinobacteria,4FH5N@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158462_k127_1474249_52	1283299.AUKG01000001_gene3477	1.793e-33	147.0	COG3832@1|root,COG3832@2|Bacteria,2IKZ7@201174|Actinobacteria	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158462_k127_1474249_50	1122939.ATUD01000007_gene2070	5.365e-42	160.0	COG0346@1|root,COG0346@2|Bacteria,2H9ZU@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_1474249_39	525904.Tter_2639	4.058e-56	207.0	COG5637@1|root,COG5637@2|Bacteria,2NRUC@2323|unclassified Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158462_k127_1474249_41	469383.Cwoe_3656	9.535e-55	201.0	COG0500@1|root,COG2226@2|Bacteria,2IREW@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158462_k127_1474249_57	1283299.AUKG01000002_gene4563	2.039e-22	103.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sig20	-	-	ko:K02405,ko:K03088	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	AbfB,CAP,Glyco_hydro_cc,Sigma70_r2
SRR25158462_k127_1474249_21	469383.Cwoe_0201	9.067e-99	336.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4CR0C@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158462_k127_1474249_42	1380390.JIAT01000009_gene1288	4.243e-54	208.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4CRBY@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158462_k127_1474249_68	1444306.JFZC01000041_gene138	5.111e-09	62.0	COG1196@1|root,COG1196@2|Bacteria,1VF7N@1239|Firmicutes,4ITQE@91061|Bacilli	91061|Bacilli	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1474249_36	935866.JAER01000009_gene671	3.64e-58	207.0	COG1528@1|root,COG1528@2|Bacteria,2IG5S@201174|Actinobacteria,4DQDV@85009|Propionibacteriales	201174|Actinobacteria	P	Iron-storage protein	bfrB	GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158462_k127_1474249_15	1283299.AUKG01000001_gene3048	1.622e-115	382.0	COG4948@1|root,COG4948@2|Bacteria,2I7AE@201174|Actinobacteria,4CPIJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1474249_9	469383.Cwoe_2805	1.454e-150	501.0	COG1982@1|root,COG1982@2|Bacteria,2GJ31@201174|Actinobacteria,4CPFW@84995|Rubrobacteria	2|Bacteria	E	PFAM Orn Lys Arg decarboxylase major region	cad	-	4.1.1.18,4.1.1.19	ko:K01582,ko:K01583,ko:K01585	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	M00133	R00462,R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.cad	OKR_DC_1,OKR_DC_1_C
SRR25158462_k127_1474249_14	1380390.JIAT01000001_gene5080	1.644e-121	409.0	COG0665@1|root,COG0665@2|Bacteria,2IEZA@201174|Actinobacteria,4CRMC@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158462_k127_1474249_29	1464048.JNZS01000051_gene2371	3.381e-68	243.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4D8TN@85008|Micromonosporales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
SRR25158462_k127_1474249_23	33876.JNXY01000006_gene1152	5.962e-97	325.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4DC77@85008|Micromonosporales	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158462_k127_1474249_25	1380347.JNII01000008_gene4085	1.524e-83	293.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4ESHI@85013|Frankiales	201174|Actinobacteria	E	PFAM extracellular solute-binding protein family 1	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158462_k127_1474249_10	469383.Cwoe_2426	6.141e-150	485.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158462_k127_1474249_1	1283299.AUKG01000001_gene2620	1.727e-211	665.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4CPUF@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158462_k127_1474249_24	1283299.AUKG01000001_gene2621	1.739e-96	323.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria,4CRKT@84995|Rubrobacteria	84995|Rubrobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRR25158462_k127_1487942_21	1122939.ATUD01000003_gene3581	5.371e-78	263.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158462_k127_1487942_41	469383.Cwoe_1356	1.641e-47	172.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4CQBN@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158462_k127_1487942_22	1283299.AUKG01000001_gene2648	4.904e-76	262.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CPMN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158462_k127_1487942_53	1519464.HY22_03285	9.55e-10	61.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158462_k127_1487942_28	469383.Cwoe_1359	6.978e-62	218.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158462_k127_1487942_3	469383.Cwoe_1360	1.466e-210	663.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CPTT@84995|Rubrobacteria	84995|Rubrobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158462_k127_1487942_19	469383.Cwoe_1361	6.05e-88	295.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CP9X@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158462_k127_1487942_12	469383.Cwoe_1362	2.439e-117	386.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CPA2@84995|Rubrobacteria	84995|Rubrobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158462_k127_1487942_1	1283299.AUKG01000001_gene3157	6.724e-239	768.0	COG2366@1|root,COG2366@2|Bacteria,2GKEN@201174|Actinobacteria,4CRSH@84995|Rubrobacteria	84995|Rubrobacteria	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
SRR25158462_k127_1487942_24	682795.AciX8_4538	3.523e-71	246.0	COG4122@1|root,COG4122@2|Bacteria,3Y4X9@57723|Acidobacteria,2JMCH@204432|Acidobacteriia	204432|Acidobacteriia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRR25158462_k127_1487942_51	908337.HMPREF9257_0112	1.701e-13	75.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,27EZF@186827|Aerococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158462_k127_1487942_38	1380390.JIAT01000011_gene2612	3.012e-52	186.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4CQ8S@84995|Rubrobacteria	84995|Rubrobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158462_k127_1487942_29	469383.Cwoe_1365	2.801e-59	207.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4CPZ7@84995|Rubrobacteria	84995|Rubrobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158462_k127_1487942_14	1283299.AUKG01000001_gene2657	2.708e-97	333.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CQ5S@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158462_k127_1487942_10	469383.Cwoe_1366	8.737e-154	491.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158462_k127_1487942_39	1283299.AUKG01000001_gene2659	1.354e-51	185.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CQ5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158462_k127_1487942_17	469383.Cwoe_1368	1.709e-90	307.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CQ1A@84995|Rubrobacteria	84995|Rubrobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158462_k127_1487942_18	469383.Cwoe_1369	3.251e-88	299.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4CQ4H@84995|Rubrobacteria	84995|Rubrobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158462_k127_1487942_2	469383.Cwoe_1370	3.344e-237	764.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CPFU@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158462_k127_1487942_33	1283299.AUKG01000001_gene2682	3.534e-57	216.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CQ4E@84995|Rubrobacteria	84995|Rubrobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158462_k127_1487942_9	1380390.JIAT01000011_gene2626	2.674e-156	508.0	COG1752@1|root,COG1752@2|Bacteria,2HPRW@201174|Actinobacteria,4CR58@84995|Rubrobacteria	84995|Rubrobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158462_k127_1487942_50	68219.JNXI01000059_gene1477	4.34e-16	81.0	COG1695@1|root,COG1695@2|Bacteria,2IQ8I@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158462_k127_1487942_7	929712.KI912613_gene4910	2.847e-171	556.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CPFF@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158462_k127_1487942_52	469383.Cwoe_1389	1.126e-10	69.0	2AXD0@1|root,31PCB@2|Bacteria,2HRSN@201174|Actinobacteria,4CTVR@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1487942_49	1380390.JIAT01000009_gene1332	9.916e-17	89.0	COG1651@1|root,COG1651@2|Bacteria,2HP5M@201174|Actinobacteria,4CQHM@84995|Rubrobacteria	84995|Rubrobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158462_k127_1487942_16	1380390.JIAT01000010_gene4081	1.181e-90	307.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4CSBE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158462_k127_1487942_43	235985.BBPN01000007_gene3324	3.523e-40	167.0	2DFE0@1|root,2ZRI8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1487942_34	67352.JODS01000004_gene6046	3.877e-57	221.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_1487942_26	469383.Cwoe_1039	2.215e-70	241.0	COG0432@1|root,COG0432@2|Bacteria,2HNZT@201174|Actinobacteria,4CQ99@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158462_k127_1487942_44	1209984.BN978_00656	2.833e-39	150.0	COG3631@1|root,COG3631@2|Bacteria,2IQIE@201174|Actinobacteria,239S1@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158462_k127_1487942_46	1283299.AUKG01000004_gene1145	1.739e-30	134.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CRKI@84995|Rubrobacteria	84995|Rubrobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158462_k127_1487942_15	929712.KI912613_gene323	6.882e-95	314.0	COG0605@1|root,COG0605@2|Bacteria,2GJV8@201174|Actinobacteria,4CQ25@84995|Rubrobacteria	84995|Rubrobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158462_k127_1487942_0	469383.Cwoe_4226	5.62e-264	821.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4CRRH@84995|Rubrobacteria	84995|Rubrobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158462_k127_1487942_48	469383.Cwoe_1559	3.106e-24	103.0	COG1773@1|root,COG1773@2|Bacteria,2GSAE@201174|Actinobacteria	201174|Actinobacteria	C	Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
SRR25158462_k127_1487942_32	929712.KI912613_gene1795	3.111e-57	207.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CQJT@84995|Rubrobacteria	84995|Rubrobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158462_k127_1487942_42	469383.Cwoe_1558	1.058e-44	171.0	COG1051@1|root,COG1051@2|Bacteria,2HG54@201174|Actinobacteria,4CT7E@84995|Rubrobacteria	84995|Rubrobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158462_k127_1487942_35	469383.Cwoe_5806	5.216e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,2HY6G@201174|Actinobacteria,4CQBA@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_1487942_8	882.DVU_2559	4.45e-164	527.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MA1I@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
SRR25158462_k127_1487942_37	469383.Cwoe_3626	4.64e-54	194.0	COG3837@1|root,COG3837@2|Bacteria,2HR5Z@201174|Actinobacteria,4CT1K@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_1487942_56	1095767.CAHD01000115_gene51	0.0004277	49.0	COG1846@1|root,COG1846@2|Bacteria,2HXXH@201174|Actinobacteria,4F1JP@85016|Cellulomonadaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158462_k127_1487942_6	469383.Cwoe_4177	1.35e-180	580.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_1487942_40	469383.Cwoe_2642	1.2e-47	195.0	COG3022@1|root,COG3022@2|Bacteria,2GJPM@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0246 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
SRR25158462_k127_1487942_30	469383.Cwoe_1568	1.762e-58	209.0	COG0132@1|root,COG0132@2|Bacteria,2GIZ2@201174|Actinobacteria,4CRYX@84995|Rubrobacteria	84995|Rubrobacteria	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SRR25158462_k127_1487942_11	469383.Cwoe_1570	1.04e-140	475.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CR0Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158462_k127_1487942_5	1380390.JIAT01000011_gene2671	2.623e-184	595.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4CR7S@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
SRR25158462_k127_1487942_23	469383.Cwoe_3621	1.143e-71	256.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4CQHG@84995|Rubrobacteria	84995|Rubrobacteria	G	glycoside hydrolase, family	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158462_k127_1487942_45	929712.KI912613_gene4483	2.269e-33	149.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRAY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRR25158462_k127_1487942_36	42256.RradSPS_1169	3.673e-55	211.0	COG0122@1|root,COG0122@2|Bacteria,2HGA7@201174|Actinobacteria,4CQF8@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158462_k127_1487942_20	1380390.JIAT01000011_gene2677	1.557e-80	278.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4CPUH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158462_k127_1487942_47	1380390.JIAT01000011_gene2678	1.432e-25	115.0	COG4770@1|root,COG4770@2|Bacteria,2HRMS@201174|Actinobacteria,4CTPT@84995|Rubrobacteria	84995|Rubrobacteria	I	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158462_k127_1487942_25	469383.Cwoe_1577	6.209e-71	253.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1487942_4	1283299.AUKG01000001_gene2410	2.818e-202	640.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CPBQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158462_k127_1487942_31	469383.Cwoe_1579	1.126e-57	223.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,4CP9N@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158462_k127_1487942_27	469383.Cwoe_1580	8.514e-66	235.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gumP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_1487942_13	929712.KI912613_gene2136	1.261e-102	341.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4CRTV@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
SRR25158462_k127_1531733_2	469383.Cwoe_2647	4.624e-125	415.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CPX5@84995|Rubrobacteria	84995|Rubrobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158462_k127_1531733_1	1380390.JIAT01000011_gene2664	1.444e-180	578.0	COG4262@1|root,COG4262@2|Bacteria,2HNDH@201174|Actinobacteria,4CP6G@84995|Rubrobacteria	84995|Rubrobacteria	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158462_k127_1531733_3	1283299.AUKG01000003_gene235	3.115e-83	287.0	COG3336@1|root,COG3336@2|Bacteria,2HPY7@201174|Actinobacteria,4CRDE@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
SRR25158462_k127_1531733_0	469383.Cwoe_1555	2.536e-250	787.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4CRP2@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158462_k127_1531733_5	1380390.JIAT01000010_gene4090	2.977e-44	168.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_1531733_4	1380390.JIAT01000014_gene6202	8.802e-60	219.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CRZ2@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 3	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158462_k127_1531733_6	269797.Mbar_A0416	1.139e-14	88.0	arCOG03561@1|root,arCOG03561@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158462_k127_1531733_8	469383.Cwoe_1428	0.0008015	52.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
SRR25158462_k127_1605488_6	414996.IL38_10520	7.966e-43	175.0	COG0748@1|root,COG0748@2|Bacteria	2|Bacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Putative_PNPOx
SRR25158462_k127_1605488_2	1380390.JIAT01000011_gene2688	1.114e-117	384.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4CPAT@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158462_k127_1605488_4	1449058.JQKT01000007_gene1628	1.026e-48	177.0	COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria,4FQ8Z@85023|Microbacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158462_k127_1605488_5	1108045.GORHZ_206_00370	9.561e-44	165.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158462_k127_1605488_7	469383.Cwoe_4928	2.583e-42	159.0	COG2062@1|root,COG2062@2|Bacteria,2HPES@201174|Actinobacteria,4CQT1@84995|Rubrobacteria	84995|Rubrobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158462_k127_1605488_10	1123508.JH636446_gene6313	0.0001741	52.0	COG2931@1|root,COG3210@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,2J3HW@203682|Planctomycetes	203682|Planctomycetes	QU	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1605488_1	1121422.AUMW01000020_gene1733	3.59e-133	436.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,24E5F@186801|Clostridia	186801|Clostridia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1605488_9	1380390.JIAT01000010_gene3397	1.398e-19	94.0	COG3631@1|root,COG3631@2|Bacteria,2IGEH@201174|Actinobacteria,4CR0V@84995|Rubrobacteria	84995|Rubrobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158462_k127_1605488_0	929712.KI912613_gene4882	1.631e-169	541.0	COG1960@1|root,COG1960@2|Bacteria,2GVSU@201174|Actinobacteria,4CRXS@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1605488_3	1283299.AUKG01000001_gene2765	3.926e-106	350.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CPTH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158462_k127_1611503_0	1380390.JIAT01000009_gene1483	3.772e-285	893.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4CP9W@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158462_k127_1612101_4	1380390.JIAT01000016_gene5504	1.993e-125	410.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4CRVW@84995|Rubrobacteria	84995|Rubrobacteria	C	Inorganic H+ pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	H_PPase
SRR25158462_k127_1612101_1	1283299.AUKG01000004_gene1091	6.204e-134	437.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158462_k127_1612101_10	469383.Cwoe_2902	9.552e-96	323.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4CPVR@84995|Rubrobacteria	84995|Rubrobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,DUF836,Put_DNA-bind_N
SRR25158462_k127_1612101_21	1283299.AUKG01000004_gene1093	2.839e-14	85.0	COG0695@1|root,COG0695@2|Bacteria,2HRFR@201174|Actinobacteria,4CTEJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutaredoxin-like domain (DUF836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158462_k127_1612101_6	266117.Rxyl_0812	1.298e-109	364.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CPNE@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158462_k127_1612101_15	469383.Cwoe_2899	3.178e-53	193.0	COG0454@1|root,COG0456@2|Bacteria,2HPAC@201174|Actinobacteria,4CQNP@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158462_k127_1612101_19	1380390.JIAT01000016_gene5511	5.244e-34	141.0	COG1214@1|root,COG1214@2|Bacteria,2HP59@201174|Actinobacteria,4CQH7@84995|Rubrobacteria	84995|Rubrobacteria	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158462_k127_1612101_18	469383.Cwoe_2896	2.346e-38	147.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CQQP@84995|Rubrobacteria	84995|Rubrobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158462_k127_1612101_12	469383.Cwoe_2893	2.064e-77	266.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158462_k127_1612101_22	667014.Thein_0870	0.00017	53.0	COG2331@1|root,COG2331@2|Bacteria,2GI34@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158462_k127_1612101_8	469383.Cwoe_2889	2.23e-103	351.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,4CQ9E@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158462_k127_1612101_17	1283299.AUKG01000004_gene1130	2.59e-40	153.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4CSPV@84995|Rubrobacteria	84995|Rubrobacteria	H	Aspartate decarboxylase	-	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SRR25158462_k127_1612101_7	1120950.KB892741_gene2627	6.098e-106	351.0	COG0414@1|root,COG0414@2|Bacteria,2GJEQ@201174|Actinobacteria,4DP0Z@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158462_k127_1612101_23	1144312.PMI09_04163	0.0002614	54.0	COG2931@1|root,COG2931@2|Bacteria,1PHQ4@1224|Proteobacteria,2V8X9@28211|Alphaproteobacteria,4BIA0@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158462_k127_1612101_16	469383.Cwoe_1522	3.62e-41	160.0	COG1633@1|root,COG1633@2|Bacteria,2ICID@201174|Actinobacteria,4CTA7@84995|Rubrobacteria	84995|Rubrobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158462_k127_1612101_13	469383.Cwoe_2883	5.415e-64	231.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CS0J@84995|Rubrobacteria	84995|Rubrobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158462_k127_1612101_2	469383.Cwoe_3307	1.027e-128	424.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158462_k127_1612101_11	78245.Xaut_4732	6.209e-89	304.0	COG0491@1|root,COG0491@2|Bacteria,1R4P1@1224|Proteobacteria,2U40Y@28211|Alphaproteobacteria,3EY8I@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_1612101_3	1380390.JIAT01000016_gene5582	2.844e-128	434.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4CPF0@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SRR25158462_k127_1612101_9	469383.Cwoe_5339	7.95e-100	333.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	xylG	-	3.6.3.17	ko:K02056,ko:K10545	ko02010,map02010	M00215,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4	-	-	ABC_tran
SRR25158462_k127_1612101_5	469383.Cwoe_5340	1.822e-122	403.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4CP9G@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158462_k127_1612101_0	1283299.AUKG01000004_gene1143	1.777e-178	565.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158462_k127_1612101_14	87626.PTD2_06604	3.28e-63	228.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,2Q099@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158462_k127_1621679_4	521098.Aaci_0158	3.022e-76	263.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,4HAR5@91061|Bacilli,279JU@186823|Alicyclobacillaceae	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1621679_10	469383.Cwoe_4689	8.115e-33	134.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4CQFX@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158462_k127_1621679_7	65393.PCC7424_4202	9.949e-65	236.0	COG4424@1|root,COG4424@2|Bacteria,1GQG7@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1621679_5	1380390.JIAT01000009_gene1186	5.477e-76	267.0	COG0392@1|root,COG0392@2|Bacteria,2HNI1@201174|Actinobacteria,4CPH1@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158462_k127_1621679_11	469383.Cwoe_1137	1.209e-25	113.0	2A23K@1|root,30QDU@2|Bacteria,2HRA7@201174|Actinobacteria,4CT74@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1621679_13	1121423.JONT01000012_gene439	1.24e-23	110.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,25ESC@186801|Clostridia,267BX@186807|Peptococcaceae	186801|Clostridia	S	pfam cbs	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158462_k127_1621679_14	1283299.AUKG01000003_gene260	1.157e-09	69.0	2AUIS@1|root,31K7B@2|Bacteria,2HP5N@201174|Actinobacteria,4CQHP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1621679_1	469383.Cwoe_1144	1.689e-215	687.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CSJJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158462_k127_1621679_12	1380390.JIAT01000009_gene2141	2.057e-24	106.0	2AWXB@1|root,31NUY@2|Bacteria,2HRCQ@201174|Actinobacteria,4CTA9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1621679_6	1380390.JIAT01000009_gene1891	2.306e-68	243.0	COG0679@1|root,COG0679@2|Bacteria,2H13X@201174|Actinobacteria,4CQBH@84995|Rubrobacteria	84995|Rubrobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158462_k127_1621679_2	469383.Cwoe_1162	9.299e-168	544.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CPJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158462_k127_1621679_3	1380390.JIAT01000009_gene1155	4.311e-154	505.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4CQ12@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158462_k127_1621679_0	1283299.AUKG01000003_gene294	1.772e-222	709.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CPCM@84995|Rubrobacteria	84995|Rubrobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158462_k127_1621679_9	1380390.JIAT01000009_gene1153	5.437e-37	141.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CQIE@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158462_k127_1621679_8	1380390.JIAT01000009_gene1152	4.326e-47	173.0	COG0839@1|root,COG0839@2|Bacteria,2HNU5@201174|Actinobacteria,4CQ2B@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q3
SRR25158462_k127_1655182_5	545243.BAEV01000203_gene2868	4.932e-07	51.0	2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,24S6J@186801|Clostridia,36MW7@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1655182_1	457424.BFAG_04907	5.468e-20	90.0	2DN97@1|root,32W7A@2|Bacteria,4P5E4@976|Bacteroidetes,2FTS2@200643|Bacteroidia,4ARGQ@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1655182_3	411489.CLOL250_01433	1.469e-13	70.0	2DPNJ@1|root,332SC@2|Bacteria,1VEK7@1239|Firmicutes,24N3R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1655182_2	980584.AFPB01000023_gene923	1.79e-15	76.0	2DTVS@1|root,33MVP@2|Bacteria,4NY96@976|Bacteroidetes,1I6YG@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1655182_0	926551.KB900730_gene1716	3.5e-65	223.0	2E4EA@1|root,32Z9I@2|Bacteria,4NTWC@976|Bacteroidetes,1IICT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_39	316274.Haur_1560	6.248e-17	82.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1665608_51	1380390.JIAT01000012_gene3310	4.044e-05	54.0	29YC7@1|root,30K6K@2|Bacteria,2HRCJ@201174|Actinobacteria,4CTA2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_52	929712.KI912613_gene56	4.836e-05	53.0	29YC7@1|root,30K6K@2|Bacteria,2HRCJ@201174|Actinobacteria,4CTA2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_17	1123320.KB889669_gene3247	1.285e-101	344.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158462_k127_1665608_27	1283299.AUKG01000003_gene233	4.196e-56	214.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
SRR25158462_k127_1665608_40	105425.BBPL01000010_gene2181	1.443e-15	85.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,2NG98@228398|Streptacidiphilus	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_1665608_43	309801.trd_0141	2.271e-07	64.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Metallophos,fn3
SRR25158462_k127_1665608_37	1123269.NX02_00855	8.813e-20	105.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158462_k127_1665608_11	1380390.JIAT01000009_gene1220	4.572e-161	522.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CP81@84995|Rubrobacteria	84995|Rubrobacteria	L	DbpA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DbpA,Helicase_C
SRR25158462_k127_1665608_18	105425.BBPL01000057_gene5466	2.98e-94	319.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,2NF1R@228398|Streptacidiphilus	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158462_k127_1665608_14	469383.Cwoe_1095	3.508e-128	417.0	COG0524@1|root,COG0524@2|Bacteria,2HPJD@201174|Actinobacteria,4CQWU@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158462_k127_1665608_8	42256.RradSPS_1617	3.263e-206	651.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158462_k127_1665608_30	1283299.AUKG01000001_gene3472	2.892e-43	165.0	COG2335@1|root,COG2335@2|Bacteria,2GJC2@201174|Actinobacteria,4CSTA@84995|Rubrobacteria	84995|Rubrobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158462_k127_1665608_41	469383.Cwoe_3112	9.274e-15	84.0	2E3FZ@1|root,32YET@2|Bacteria,2IGAC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_34	1122939.ATUD01000001_gene494	3.528e-26	115.0	28VU7@1|root,2ZHVW@2|Bacteria,2HRXI@201174|Actinobacteria,4CU0P@84995|Rubrobacteria	84995|Rubrobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158462_k127_1665608_25	580327.Tthe_2568	1.607e-59	225.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,42G1D@68295|Thermoanaerobacterales	186801|Clostridia	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158462_k127_1665608_9	1283299.AUKG01000001_gene1277	8.391e-196	623.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4CRF1@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158462_k127_1665608_5	349521.HCH_04995	1.115e-255	804.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1XMDW@135619|Oceanospirillales	135619|Oceanospirillales	M	dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
SRR25158462_k127_1665608_6	562970.Btus_1382	3.013e-244	802.0	COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,279I7@186823|Alicyclobacillaceae	91061|Bacilli	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	odhA	GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158462_k127_1665608_46	469383.Cwoe_1043	2.281e-06	53.0	2AXGF@1|root,31PG3@2|Bacteria,2HRV7@201174|Actinobacteria,4CTYJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_1	196162.Noca_2876	0.0	1202.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4DPP4@85009|Propionibacteriales	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158462_k127_1665608_21	216594.MMAR_2623	2.858e-75	265.0	COG0300@1|root,COG0300@2|Bacteria,2I64P@201174|Actinobacteria,236NE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158462_k127_1665608_31	1380390.JIAT01000014_gene6234	7.103e-41	166.0	COG0791@1|root,COG0791@2|Bacteria,2HQTI@201174|Actinobacteria,4CSIU@84995|Rubrobacteria	84995|Rubrobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_12	1380390.JIAT01000011_gene2578	5.114e-141	456.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158462_k127_1665608_13	1343740.M271_43670	9.695e-138	458.0	COG0687@1|root,COG0687@2|Bacteria	2|Bacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
SRR25158462_k127_1665608_15	1380390.JIAT01000011_gene2576	1.739e-122	398.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4CSJC@84995|Rubrobacteria	84995|Rubrobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158462_k127_1665608_16	1380390.JIAT01000011_gene2575	1.286e-107	356.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4CQ2P@84995|Rubrobacteria	201174|Actinobacteria	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158462_k127_1665608_2	1380390.JIAT01000009_gene2164	1.049e-286	892.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158462_k127_1665608_49	58123.JOFJ01000029_gene1121	1.687e-05	55.0	2E3YX@1|root,3215V@2|Bacteria,2I26P@201174|Actinobacteria,4EQIJ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_4	1380390.JIAT01000009_gene2171	4.102e-256	801.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158462_k127_1665608_10	469383.Cwoe_5517	5.309e-164	521.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria,4CPD2@84995|Rubrobacteria	84995|Rubrobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158462_k127_1665608_29	1380390.JIAT01000014_gene6156	4.137e-47	186.0	COG1595@1|root,COG1595@2|Bacteria,2IJIK@201174|Actinobacteria,4CRT2@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158462_k127_1665608_45	1380390.JIAT01000009_gene1383	1.472e-06	62.0	2AVU4@1|root,31MMQ@2|Bacteria,2HQAN@201174|Actinobacteria,4CRUS@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_26	469383.Cwoe_5823	1.013e-58	229.0	COG0483@1|root,COG0483@2|Bacteria,2HNNN@201174|Actinobacteria,4CPT9@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158462_k127_1665608_3	469383.Cwoe_5824	3.377e-259	830.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158462_k127_1665608_19	1283299.AUKG01000001_gene1973	6.464e-93	319.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158462_k127_1665608_35	1283299.AUKG01000001_gene1967	6.533e-23	109.0	COG0730@1|root,COG0730@2|Bacteria,2HU3V@201174|Actinobacteria,4CTHN@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158462_k127_1665608_33	1283299.AUKG01000001_gene1966	5.532e-31	125.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158462_k127_1665608_24	929712.KI912613_gene939	6.985e-61	220.0	COG1877@1|root,COG1877@2|Bacteria,2HP2R@201174|Actinobacteria,4CQDQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158462_k127_1665608_32	469383.Cwoe_5833	7.53e-36	143.0	2AUAQ@1|root,31JYC@2|Bacteria,2HNZD@201174|Actinobacteria,4CQ8V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1665608_7	469383.Cwoe_5838	5.301e-208	664.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158462_k127_1665608_38	469383.Cwoe_4028	3.081e-19	95.0	COG3023@1|root,COG3023@2|Bacteria,2HCX7@201174|Actinobacteria	201174|Actinobacteria	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158462_k127_1665608_20	290397.Adeh_2624	2.382e-81	283.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158462_k127_1665608_28	1283299.AUKG01000001_gene1956	7.344e-51	182.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4CQED@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158462_k127_1665608_47	1159870.KB907784_gene1429	2.45e-06	56.0	COG1942@1|root,COG1942@2|Bacteria,1NG98@1224|Proteobacteria,2WFVM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the 4-oxalocrotonate tautomerase family	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158462_k127_1665608_0	469383.Cwoe_5846	0.0	1280.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158462_k127_1665608_22	1123258.AQXZ01000015_gene4571	4.397e-74	258.0	COG4221@1|root,COG4221@2|Bacteria,2GKJ8@201174|Actinobacteria,4FXZ5@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_1665608_23	314230.DSM3645_19063	1.768e-72	252.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2IYAH@203682|Planctomycetes	203682|Planctomycetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
SRR25158462_k127_1711600_18	469383.Cwoe_1886	3.997e-141	464.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158462_k127_1711600_125	1380390.JIAT01000014_gene6081	4.007e-28	119.0	COG0517@1|root,COG0517@2|Bacteria,2HPZ3@201174|Actinobacteria,4CREF@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158462_k127_1711600_40	1122939.ATUD01000002_gene1284	1.707e-103	355.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CP9P@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158462_k127_1711600_24	469383.Cwoe_1889	4.54e-133	439.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CQTJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158462_k127_1711600_117	1121413.JMKT01000009_gene2170	3.076e-34	132.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158462_k127_1711600_31	1380390.JIAT01000009_gene557	1.482e-114	383.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4CQPE@84995|Rubrobacteria	84995|Rubrobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
SRR25158462_k127_1711600_66	1283299.AUKG01000002_gene5113	3.36e-74	273.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158462_k127_1711600_79	1380390.JIAT01000010_gene4761	4.167e-63	227.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158462_k127_1711600_35	1283299.AUKG01000002_gene5111	9.719e-111	395.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158462_k127_1711600_101	1125863.JAFN01000001_gene1604	1.313e-45	186.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158462_k127_1711600_138	929712.KI912613_gene4676	1.124e-20	94.0	2A00B@1|root,30N2D@2|Bacteria,2HP1D@201174|Actinobacteria,4CQBW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_20	469383.Cwoe_1896	1.721e-137	454.0	COG0438@1|root,COG0438@2|Bacteria,2H432@201174|Actinobacteria,4CR80@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_1711600_89	469383.Cwoe_1903	4.127e-53	197.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2GNXA@201174|Actinobacteria	201174|Actinobacteria	C	I and II form the functional core of the enzyme complex. electrons originating in cytochrome C are transferred via HemE a and cu(a) to the binuclear center formed by HemE A3 and cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158462_k127_1711600_2	1283299.AUKG01000001_gene3221	2.301e-280	874.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CS3H@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SRR25158462_k127_1711600_95	469383.Cwoe_1901	2.591e-50	190.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158462_k127_1711600_58	1380390.JIAT01000014_gene6067	7.977e-82	277.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CSHZ@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158462_k127_1711600_151	1444306.JFZC01000041_gene138	1.045e-12	72.0	COG1196@1|root,COG1196@2|Bacteria,1VF7N@1239|Firmicutes,4ITQE@91061|Bacilli	91061|Bacilli	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_88	469383.Cwoe_5217	2.039e-53	197.0	2AUAR@1|root,31JYD@2|Bacteria,2HNZF@201174|Actinobacteria,4CQ8Y@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_57	469383.Cwoe_5475	1.66e-82	286.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4CRU2@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158462_k127_1711600_144	469383.Cwoe_1897	5.136e-18	96.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	pbrT	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,Cytochrome_CBB3,FTR1
SRR25158462_k127_1711600_102	469383.Cwoe_1905	4.111e-44	164.0	COG0517@1|root,COG0517@2|Bacteria,2I6I8@201174|Actinobacteria,4CQHZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158462_k127_1711600_36	1380390.JIAT01000014_gene6059	2.864e-110	365.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4CS5J@84995|Rubrobacteria	84995|Rubrobacteria	O	UbiA prenyltransferase family	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158462_k127_1711600_37	469383.Cwoe_1909	5.809e-110	384.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CP91@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158462_k127_1711600_137	1120951.AUBG01000001_gene889	9.969e-23	106.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,4NMMP@976|Bacteroidetes,1I8A6@117743|Flavobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C
SRR25158462_k127_1711600_49	1122939.ATUD01000002_gene1294	2.366e-93	329.0	COG0671@1|root,COG0671@2|Bacteria,2HPYC@201174|Actinobacteria,4CRDJ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158462_k127_1711600_61	469383.Cwoe_1913	3.503e-79	278.0	COG0392@1|root,COG0392@2|Bacteria,2HQ3T@201174|Actinobacteria,4CRKA@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158462_k127_1711600_22	469383.Cwoe_1914	9.945e-135	436.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CP86@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158462_k127_1711600_116	1283299.AUKG01000001_gene2518	5.499e-35	136.0	COG0025@1|root,COG0025@2|Bacteria,2I2S7@201174|Actinobacteria,4CT3S@84995|Rubrobacteria	84995|Rubrobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158462_k127_1711600_56	469383.Cwoe_2190	9.041e-84	302.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158462_k127_1711600_71	469383.Cwoe_2162	9.091e-73	267.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4CS43@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158462_k127_1711600_26	68223.JNZY01000007_gene3158	4.905e-127	420.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1711600_80	469383.Cwoe_5918	8.285e-63	242.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria	201174|Actinobacteria	EH	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158462_k127_1711600_109	469383.Cwoe_2926	4.391e-39	160.0	COG5640@1|root,COG5640@2|Bacteria,2GN18@201174|Actinobacteria,4CTGT@84995|Rubrobacteria	84995|Rubrobacteria	M	SMART peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158462_k127_1711600_17	644966.Tmar_2129	3.986e-149	495.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WCX5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158462_k127_1711600_152	1283299.AUKG01000001_gene3251	1.266e-12	79.0	2B4EW@1|root,31X6H@2|Bacteria,2HQY1@201174|Actinobacteria,4CSQH@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_130	469383.Cwoe_1917	7.309e-25	109.0	COG0702@1|root,COG0702@2|Bacteria,2HQUJ@201174|Actinobacteria,4CSM6@84995|Rubrobacteria	84995|Rubrobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158462_k127_1711600_32	1041146.ATZB01000013_gene4357	2.04e-114	372.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,4B7AE@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158462_k127_1711600_105	1283299.AUKG01000001_gene3255	2.353e-42	173.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4CQAZ@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158462_k127_1711600_60	1380390.JIAT01000016_gene5642	4.127e-81	286.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQG8@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158462_k127_1711600_122	469383.Cwoe_1919	9.528e-32	134.0	COG1765@1|root,COG1765@2|Bacteria,2IIKU@201174|Actinobacteria,4CQ86@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158462_k127_1711600_108	1304865.JAGF01000001_gene3122	1.145e-39	168.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria	201174|Actinobacteria	S	adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158462_k127_1711600_21	469383.Cwoe_1920	3.022e-136	449.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158462_k127_1711600_129	1321778.HMPREF1982_00386	6.235e-25	121.0	2D56M@1|root,32TIB@2|Bacteria,1VCAG@1239|Firmicutes,24ITR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_123	1122939.ATUD01000001_gene115	4.281e-31	126.0	COG1917@1|root,COG1917@2|Bacteria,2HN4T@201174|Actinobacteria,4CQJ2@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_96	83332.Rv2829c	6.782e-50	180.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158462_k127_1711600_147	83332.Rv2830c	4.085e-16	81.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040007,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0080090,GO:2000112	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158462_k127_1711600_160	1380390.JIAT01000009_gene967	4.287e-08	59.0	2B5N1@1|root,31YH9@2|Bacteria,2HR5Y@201174|Actinobacteria,4CT1J@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_51	298654.FraEuI1c_0677	1.955e-90	306.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4ESDQ@85013|Frankiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158462_k127_1711600_46	1283299.AUKG01000002_gene4971	2.751e-96	321.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria,4CQPG@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158462_k127_1711600_103	1463921.JODF01000083_gene26	1.539e-42	175.0	2EWUX@1|root,33Q6G@2|Bacteria,2IKE1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_166	935866.JAER01000002_gene1980	7.086e-07	63.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,PATR,Peptidase_S74
SRR25158462_k127_1711600_174	309801.trd_0141	0.0001936	52.0	COG1409@1|root,COG4733@1|root,COG1409@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Metallophos,fn3
SRR25158462_k127_1711600_157	1246995.AFR_02350	5.158e-11	71.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,Laminin_G_3,fn3
SRR25158462_k127_1711600_14	1209984.BN978_03765	3.144e-167	543.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,2370B@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158462_k127_1711600_176	909613.UO65_0324	0.0003457	48.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXQC@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
SRR25158462_k127_1711600_107	497964.CfE428DRAFT_3541	1.378e-40	159.0	COG0791@1|root,COG0791@2|Bacteria,46VUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_48	1313172.YM304_11060	3.322e-94	320.0	2DB7V@1|root,2Z7NX@2|Bacteria,2I9CJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_163	1131814.JAFO01000001_gene970	1.824e-07	58.0	2EI68@1|root,33BXK@2|Bacteria,1NH2E@1224|Proteobacteria,2UJAP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_92	1380354.JIAN01000006_gene665	1.652e-51	190.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria	201174|Actinobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,Methyltransf_11
SRR25158462_k127_1711600_47	469383.Cwoe_3910	2.428e-94	319.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CRGJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158462_k127_1711600_82	1449976.KALB_6090	6.791e-61	218.0	COG1309@1|root,COG1309@2|Bacteria,2GNY5@201174|Actinobacteria,4E760@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	ethR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K21961	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158462_k127_1711600_62	1229203.KI301992_gene580	1.412e-78	271.0	COG1028@1|root,COG1028@2|Bacteria,2I3KE@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158462_k127_1711600_9	1415780.JPOG01000001_gene385	2.961e-194	631.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,1RP8X@1236|Gammaproteobacteria,1X3XD@135614|Xanthomonadales	135614|Xanthomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8
SRR25158462_k127_1711600_126	1380390.JIAT01000012_gene3211	1.807e-25	115.0	COG5470@1|root,COG5470@2|Bacteria,2IM3I@201174|Actinobacteria,4CQGY@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
SRR25158462_k127_1711600_141	1122182.KB903813_gene2442	1.287e-19	91.0	2E73E@1|root,331MX@2|Bacteria,2IRHV@201174|Actinobacteria,4DKDP@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158462_k127_1711600_120	105422.BBPM01000020_gene2781	3.024e-33	141.0	2FAZ3@1|root,3435V@2|Bacteria,2IDWY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_169	1122939.ATUD01000009_gene3105	2.7e-06	59.0	COG0810@1|root,COG0810@2|Bacteria,2GIZY@201174|Actinobacteria,4CU3X@84995|Rubrobacteria	84995|Rubrobacteria	M	Htaa	-	-	-	-	-	-	-	-	-	-	-	-	HtaA
SRR25158462_k127_1711600_50	1283299.AUKG01000001_gene1968	1.994e-92	317.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4CRWR@84995|Rubrobacteria	84995|Rubrobacteria	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158462_k127_1711600_42	1380390.JIAT01000009_gene1996	1.043e-101	339.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4CQYF@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_1711600_3	981369.JQMJ01000004_gene6418	2.325e-270	846.0	COG3158@1|root,COG3158@2|Bacteria,2GMPQ@201174|Actinobacteria,2NFZA@228398|Streptacidiphilus	201174|Actinobacteria	P	K+ potassium transporter	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SRR25158462_k127_1711600_11	469383.Cwoe_3280	1.264e-185	586.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CPTW@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158462_k127_1711600_77	1380390.JIAT01000010_gene3558	1.326e-64	229.0	COG0625@1|root,COG0625@2|Bacteria,2HQC6@201174|Actinobacteria,4CRWK@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158462_k127_1711600_149	1370120.AUWR01000035_gene1893	1.014e-13	78.0	2BEM9@1|root,328CR@2|Bacteria,2IM86@201174|Actinobacteria,23AFH@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_115	1172180.KB911785_gene427	1.781e-37	149.0	2E4BX@1|root,32Z7H@2|Bacteria,2IM6W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR25158462_k127_1711600_171	1454010.JEOE01000011_gene2414	6.479e-06	57.0	2DN8C@1|root,32W33@2|Bacteria,2GTQ4@201174|Actinobacteria,4F338@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_55	469383.Cwoe_4520	2.421e-84	289.0	COG2102@1|root,COG2102@2|Bacteria,2INXV@201174|Actinobacteria	201174|Actinobacteria	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
SRR25158462_k127_1711600_114	1283299.AUKG01000001_gene1286	1.05e-37	154.0	COG3837@1|root,COG3837@2|Bacteria	2|Bacteria	S	Cupin domain	manC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_1711600_7	1380390.JIAT01000010_gene4550	1.93e-216	689.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CR6V@84995|Rubrobacteria	84995|Rubrobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158462_k127_1711600_16	469383.Cwoe_0401	3.805e-151	499.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158462_k127_1711600_98	1283299.AUKG01000001_gene2480	1.056e-48	181.0	2B571@1|root,31Y0X@2|Bacteria,2HR33@201174|Actinobacteria,4CSYD@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_1711600_153	278957.ABEA03000174_gene3405	3.685e-12	80.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46Z61@74201|Verrucomicrobia,3K8JK@414999|Opitutae	414999|Opitutae	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,DUF3494,PATR
SRR25158462_k127_1711600_165	357808.RoseRS_1673	5.446e-07	63.0	COG1470@1|root,COG1716@1|root,COG1470@2|Bacteria,COG1716@2|Bacteria,2G8JT@200795|Chloroflexi	200795|Chloroflexi	T	FHA domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158462_k127_1711600_158	1071073.KI530536_gene1077	1.204e-08	63.0	COG1396@1|root,COG1396@2|Bacteria,1UWCU@1239|Firmicutes,4I3XD@91061|Bacilli,1ZK0M@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_1711600_1	469383.Cwoe_3663	2.451e-290	909.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4CRH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158462_k127_1711600_118	1229780.BN381_450062	1.675e-33	150.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158462_k127_1711600_100	1172180.KB911802_gene5196	1.061e-46	174.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158462_k127_1711600_83	1122939.ATUD01000003_gene3384	3.748e-59	229.0	COG2114@1|root,COG2114@2|Bacteria,2I900@201174|Actinobacteria,4CU3M@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158462_k127_1711600_128	1283299.AUKG01000005_gene88	3.047e-25	120.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4CQM8@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158462_k127_1711600_72	219305.MCAG_03355	2.194e-67	246.0	COG2372@1|root,COG2372@2|Bacteria,2GIWH@201174|Actinobacteria,4DAFC@85008|Micromonosporales	201174|Actinobacteria	S	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_0	469383.Cwoe_0469	3.228e-314	981.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158462_k127_1711600_28	469383.Cwoe_5696	1.826e-121	399.0	COG0640@1|root,COG3177@1|root,COG0640@2|Bacteria,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	ybzH	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Lant_dehydr_N
SRR25158462_k127_1711600_41	675635.Psed_5849	2.253e-103	362.0	COG0644@1|root,COG0644@2|Bacteria,2HZIE@201174|Actinobacteria,4EBY4@85010|Pseudonocardiales	201174|Actinobacteria	C	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_30	469383.Cwoe_4233	2.232e-120	392.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158462_k127_1711600_73	1415780.JPOG01000001_gene9	5.719e-67	235.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,1RYP5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158462_k127_1711600_145	1306406.ASHX01000002_gene4524	3.104e-17	97.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria	201174|Actinobacteria	Q	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158462_k127_1711600_81	1122939.ATUD01000002_gene1216	2.079e-62	230.0	COG4942@1|root,COG4942@2|Bacteria,2GP1Y@201174|Actinobacteria,4CPU0@84995|Rubrobacteria	84995|Rubrobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158462_k127_1711600_44	1183438.GKIL_3050	2.086e-97	351.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K12685,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	-	-	Peptidase_S8,TIG
SRR25158462_k127_1711600_29	1172186.KB911473_gene5506	2.273e-121	394.0	COG3000@1|root,COG3000@2|Bacteria,2GMF0@201174|Actinobacteria,238AV@1762|Mycobacteriaceae	201174|Actinobacteria	I	Fatty acid hydroxylase superfamily	erg3	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158462_k127_1711600_75	711393.AYRX01000079_gene5273	6.421e-66	233.0	COG0259@1|root,COG0259@2|Bacteria,2IFQZ@201174|Actinobacteria	201174|Actinobacteria	H	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region	-	-	1.10.3.16	ko:K20262	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	R11490,R11491,R11492	RC03450,RC03451	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158462_k127_1711600_148	1144305.PMI02_00369	4.104e-14	83.0	COG0631@1|root,COG0631@2|Bacteria,1N7TW@1224|Proteobacteria,2UG3B@28211|Alphaproteobacteria,2KDH0@204457|Sphingomonadales	204457|Sphingomonadales	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
SRR25158462_k127_1711600_168	1307436.PBF_16374	2.447e-06	59.0	2BAM0@1|root,3241T@2|Bacteria,1UC9P@1239|Firmicutes,4INS4@91061|Bacilli,1ZNV7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_34	469383.Cwoe_3638	9.74e-112	366.0	COG1254@1|root,COG1254@2|Bacteria,2IT6J@201174|Actinobacteria,4CTJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158462_k127_1711600_142	2074.JNYD01000003_gene3442	3.344e-19	89.0	arCOG09452@1|root,335JP@2|Bacteria,2IBPA@201174|Actinobacteria,4E25A@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_15	1380390.JIAT01000017_gene5272	1.197e-152	509.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CU6W@84995|Rubrobacteria	84995|Rubrobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
SRR25158462_k127_1711600_68	469383.Cwoe_0783	2.333e-73	252.0	COG3324@1|root,COG3324@2|Bacteria,2I6WX@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_85	390989.JOEG01000008_gene1438	4.291e-56	202.0	COG0640@1|root,COG0640@2|Bacteria,2IEHG@201174|Actinobacteria,4DDCS@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_1711600_33	452652.KSE_67120	3.978e-113	387.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,2M4ZX@2063|Kitasatospora	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158462_k127_1711600_52	1283299.AUKG01000001_gene1647	2.587e-87	296.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria,4CU4M@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158462_k127_1711600_4	469383.Cwoe_0843	9.98e-259	806.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158462_k127_1711600_13	1283299.AUKG01000002_gene3733	1.119e-174	556.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CPP6@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1711600_139	1121272.KB903261_gene6063	6.941e-20	95.0	COG5483@1|root,COG5483@2|Bacteria,2IFJK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158462_k127_1711600_172	469383.Cwoe_5418	9.445e-06	58.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03286,ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,1.B.6,3.A.1.109.4	-	-	OEP,OmpA
SRR25158462_k127_1711600_112	1380390.JIAT01000012_gene3005	6.75e-38	149.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
SRR25158462_k127_1711600_74	469383.Cwoe_0231	4.265e-66	231.0	COG1309@1|root,COG1309@2|Bacteria,2GKE2@201174|Actinobacteria,4CRRG@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_1711600_8	469383.Cwoe_0232	2.962e-200	628.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4CPRK@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_1711600_23	1283299.AUKG01000005_gene170	2.377e-134	434.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4CS54@84995|Rubrobacteria	84995|Rubrobacteria	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
SRR25158462_k127_1711600_5	1283299.AUKG01000005_gene168	3.747e-245	779.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CP83@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158462_k127_1711600_140	469383.Cwoe_3110	1.167e-19	90.0	COG1724@1|root,COG1724@2|Bacteria,2GX5V@201174|Actinobacteria	201174|Actinobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158462_k127_1711600_150	469383.Cwoe_3111	6.563e-13	70.0	COG1598@1|root,COG1598@2|Bacteria,2GZ8D@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_146	469383.Cwoe_1200	2.032e-16	86.0	2B7Q6@1|root,320W2@2|Bacteria,2HRM4@201174|Actinobacteria,4CTNY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_39	2002.JOEQ01000008_gene1129	1.872e-104	346.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4EIXN@85012|Streptosporangiales	201174|Actinobacteria	S	Phenazine biosynthesis-like protein	phzF	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158462_k127_1711600_76	469383.Cwoe_3047	9.527e-65	224.0	297W1@1|root,2ZV2M@2|Bacteria,2II0V@201174|Actinobacteria,4CT5W@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
SRR25158462_k127_1711600_119	1120934.KB894404_gene578	2.161e-33	140.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4E417@85010|Pseudonocardiales	201174|Actinobacteria	Q	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
SRR25158462_k127_1711600_135	430998.XP_007677679.1	2.078e-23	111.0	2EQ4A@1|root,2ST70@2759|Eukaryota,3AADF@33154|Opisthokonta,3P8AF@4751|Fungi,3QYYA@4890|Ascomycota,204JB@147541|Dothideomycetes,3MNFK@451867|Dothideomycetidae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_94	1101188.KI912155_gene2289	8.201e-51	181.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria,1WADX@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
SRR25158462_k127_1711600_84	105425.BBPL01000003_gene6752	6.067e-57	208.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria,2NGID@228398|Streptacidiphilus	201174|Actinobacteria	K	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
SRR25158462_k127_1711600_121	1229780.BN381_330001	1.217e-32	142.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,2IFXI@201174|Actinobacteria	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158462_k127_1711600_124	1122939.ATUD01000003_gene3399	2.102e-30	134.0	COG5609@1|root,COG5609@2|Bacteria,2HR3Q@201174|Actinobacteria,4CSZ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
SRR25158462_k127_1711600_136	469383.Cwoe_2069	2.722e-23	108.0	COG3369@1|root,COG3369@2|Bacteria,2HNFR@201174|Actinobacteria,4CQRA@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158462_k127_1711600_25	469383.Cwoe_2070	1.72e-132	432.0	28INB@1|root,2Z8NQ@2|Bacteria,2GM2K@201174|Actinobacteria	201174|Actinobacteria	S	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
SRR25158462_k127_1711600_38	1122611.KB903940_gene1776	6.586e-108	366.0	COG1215@1|root,COG1215@2|Bacteria,2IAQ1@201174|Actinobacteria,4EMAC@85012|Streptosporangiales	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
SRR25158462_k127_1711600_70	1123320.KB889664_gene1347	8.062e-73	256.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR25158462_k127_1711600_59	1380390.JIAT01000010_gene3992	1.509e-81	282.0	COG3685@1|root,COG3685@2|Bacteria,2HRWK@201174|Actinobacteria,4CTZZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158462_k127_1711600_132	211114.JOEF01000031_gene1870	9.91e-25	116.0	COG3427@1|root,COG3427@2|Bacteria,2I3CZ@201174|Actinobacteria,4EDZV@85010|Pseudonocardiales	201174|Actinobacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_97	469383.Cwoe_3196	1.799e-49	187.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4CQCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158462_k127_1711600_127	266117.Rxyl_3111	1.904e-25	117.0	2B8WW@1|root,32276@2|Bacteria,2H6HP@201174|Actinobacteria	201174|Actinobacteria	M	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158462_k127_1711600_65	1254432.SCE1572_00235	1.4e-76	267.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2WM2N@28221|Deltaproteobacteria,2Z3DN@29|Myxococcales	28221|Deltaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_1711600_110	44454.NF84_18785	9.272e-39	150.0	2AW22@1|root,31MWT@2|Bacteria,2IKWE@201174|Actinobacteria,238T9@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
SRR25158462_k127_1711600_161	1123288.SOV_4c01810	1.052e-07	62.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4H5BR@909932|Negativicutes	909932|Negativicutes	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
SRR25158462_k127_1711600_27	266117.Rxyl_0719	2.824e-122	401.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4CPQF@84995|Rubrobacteria	84995|Rubrobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158462_k127_1711600_10	749927.AMED_4283	2.394e-192	607.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DXR5@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase GroES-like	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158462_k127_1711600_43	469383.Cwoe_3430	1.883e-99	335.0	COG3569@1|root,COG3569@2|Bacteria,2GJTH@201174|Actinobacteria,4CR90@84995|Rubrobacteria	84995|Rubrobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_I
SRR25158462_k127_1711600_86	1283299.AUKG01000001_gene1940	8.475e-56	210.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158462_k127_1711600_19	1172188.KB911822_gene763	1.045e-140	471.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4FJ6N@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Lipase_GDSL_2
SRR25158462_k127_1711600_6	357808.RoseRS_2053	1.22e-218	700.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,3765E@32061|Chloroflexia	32061|Chloroflexia	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158462_k127_1711600_87	1313172.YM304_29230	5.097e-55	199.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria	201174|Actinobacteria	P	reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158462_k127_1711600_67	266117.Rxyl_1070	8.289e-74	255.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158462_k127_1711600_45	882083.SacmaDRAFT_5077	9.641e-97	326.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DXUF@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	fgd	-	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158462_k127_1711600_93	68170.KL590557_gene5323	6.243e-51	185.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4E4PZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158462_k127_1711600_104	1211114.ALIP01000001_gene515	2.231e-42	162.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,1S3YJ@1236|Gammaproteobacteria,1X6S3@135614|Xanthomonadales	135614|Xanthomonadales	K	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158462_k127_1711600_12	1242864.D187_005776	7.812e-182	579.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,437V1@68525|delta/epsilon subdivisions,2X34I@28221|Deltaproteobacteria,2YU7X@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_1711600_106	1380390.JIAT01000009_gene1210	3.742e-42	158.0	COG3795@1|root,COG3795@2|Bacteria,2IHYC@201174|Actinobacteria,4CTFQ@84995|Rubrobacteria	84995|Rubrobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158462_k127_1711600_78	469383.Cwoe_4028	8.381e-64	224.0	COG3023@1|root,COG3023@2|Bacteria,2HCX7@201174|Actinobacteria	201174|Actinobacteria	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158462_k127_1711600_90	1380390.JIAT01000013_gene295	1.972e-52	192.0	COG3685@1|root,COG3685@2|Bacteria,2II1C@201174|Actinobacteria,4CSVV@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
SRR25158462_k127_1711600_91	926560.KE387027_gene261	2.188e-52	209.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1WMF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158462_k127_1711600_54	1380390.JIAT01000014_gene6170	9.339e-85	285.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4CPWN@84995|Rubrobacteria	84995|Rubrobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158462_k127_1711600_162	929712.KI912613_gene81	1.653e-07	61.0	COG3668@1|root,33GBB@2|Bacteria,2I3D9@201174|Actinobacteria	201174|Actinobacteria	S	negative regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_173	1896.JOAU01000007_gene5688	1.002e-05	58.0	COG0640@1|root,COG0640@2|Bacteria,2IQKG@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_1711600_69	1380390.JIAT01000014_gene6198	3.458e-73	252.0	COG0546@1|root,COG0546@2|Bacteria,2GIU8@201174|Actinobacteria,4CPZN@84995|Rubrobacteria	84995|Rubrobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158462_k127_1711600_64	1283299.AUKG01000002_gene4555	4.475e-77	266.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158462_k127_1711600_133	43354.JOIJ01000011_gene2698	3.281e-24	118.0	2DPE5@1|root,331QG@2|Bacteria,2IQE8@201174|Actinobacteria,4E5S3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_167	1380390.JIAT01000014_gene6066	1.472e-06	59.0	COG1113@1|root,COG1113@2|Bacteria,2HQNZ@201174|Actinobacteria,4CS9Z@84995|Rubrobacteria	84995|Rubrobacteria	E	amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1711600_63	469383.Cwoe_3252	1.606e-77	271.0	COG0668@1|root,COG0668@2|Bacteria,2IQWA@201174|Actinobacteria	201174|Actinobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158462_k127_1711600_154	1380390.JIAT01000009_gene971	6.645e-12	70.0	COG1366@1|root,COG1366@2|Bacteria,2HRM9@201174|Actinobacteria,4CTP4@84995|Rubrobacteria	84995|Rubrobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158462_k127_1711600_99	469383.Cwoe_4563	7.313e-48	183.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158462_k127_1711600_143	1283299.AUKG01000001_gene2083	2.048e-18	91.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1729948_0	469383.Cwoe_3204	6.87e-322	998.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CPEA@84995|Rubrobacteria	84995|Rubrobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158462_k127_1729948_18	402881.Plav_1090	3.797e-40	160.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria,1JP4C@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K22479	-	-	-	-	ko00000	-	-	-	Acetyltransf_3
SRR25158462_k127_1729948_3	469383.Cwoe_3203	1.424e-170	543.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CP5S@84995|Rubrobacteria	84995|Rubrobacteria	EF	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158462_k127_1729948_4	1380390.JIAT01000010_gene4856	2.049e-163	536.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CPDG@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158462_k127_1729948_5	469383.Cwoe_3200	7.259e-144	463.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CPT1@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158462_k127_1729948_14	469383.Cwoe_3199	1.071e-74	257.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4CQBB@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158462_k127_1729948_12	1122939.ATUD01000005_gene2702	1.568e-91	310.0	COG1234@1|root,COG1234@2|Bacteria,2GJT2@201174|Actinobacteria,4CRBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158462_k127_1729948_15	1207063.P24_18779	5.919e-63	229.0	2EWAU@1|root,33PPI@2|Bacteria,1NUXR@1224|Proteobacteria,2UREJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1729948_11	469383.Cwoe_1310	1.092e-91	316.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4CSBE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158462_k127_1729948_17	1122939.ATUD01000003_gene3544	1.705e-45	176.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CQI8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158462_k127_1729948_10	1122939.ATUD01000005_gene2680	6.297e-101	349.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CPZJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158462_k127_1729948_9	469383.Cwoe_3175	3.122e-103	348.0	COG1208@1|root,COG1208@2|Bacteria,2GKHA@201174|Actinobacteria,4CQZH@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR25158462_k127_1729948_20	469383.Cwoe_3192	3.084e-34	132.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CQC7@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158462_k127_1729948_1	469383.Cwoe_3191	1.211e-192	611.0	COG0498@1|root,COG0498@2|Bacteria,2GNM0@201174|Actinobacteria,4CPCC@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158462_k127_1729948_6	469383.Cwoe_3190	1.023e-129	422.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CR9X@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158462_k127_1729948_16	485913.Krac_8872	1.342e-59	210.0	COG0537@1|root,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi	200795|Chloroflexi	FG	Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT,NUDIX
SRR25158462_k127_1729948_2	469383.Cwoe_3174	7.617e-191	605.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158462_k127_1729948_7	469383.Cwoe_3173	2.062e-121	418.0	COG0491@1|root,COG0491@2|Bacteria,2HGYI@201174|Actinobacteria,4CQY2@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_1729948_21	246196.MSMEI_2085	1.197e-28	124.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria,23A0Y@1762|Mycobacteriaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB2	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158462_k127_1729948_19	318424.EU78_08945	3.027e-34	136.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,2396M@1762|Mycobacteriaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158462_k127_1729948_8	469383.Cwoe_3189	8.929e-108	358.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CR9C@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158462_k127_1729948_13	1283299.AUKG01000001_gene2979	6.12e-76	267.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4CQMB@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_1729948_23	469383.Cwoe_1712	6.891e-19	102.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_1900843_6	1121090.KB894700_gene3295	2.212e-84	289.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4IU6J@91061|Bacilli	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
SRR25158462_k127_1900843_8	991905.SL003B_2155	2.165e-61	225.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria,4BS0J@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158462_k127_1900843_9	469383.Cwoe_4561	1.782e-24	113.0	2DPKA@1|root,332H3@2|Bacteria,2I2YH@201174|Actinobacteria,4CQ8H@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158462_k127_1900843_4	266117.Rxyl_2251	9.661e-112	370.0	COG3938@1|root,COG3938@2|Bacteria,2GM47@201174|Actinobacteria,4CPQZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Proline racemase	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
SRR25158462_k127_1900843_1	469383.Cwoe_5281	4.266e-220	695.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4CPIR@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158462_k127_1900843_0	469383.Cwoe_0911	6.63e-239	743.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158462_k127_1900843_2	882082.SaccyDRAFT_2422	1.791e-158	505.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4DYMT@85010|Pseudonocardiales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158462_k127_1900843_10	469383.Cwoe_5279	7.142e-14	76.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_33
SRR25158462_k127_1900843_3	1283299.AUKG01000004_gene914	2.484e-128	420.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria,4CP9B@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158462_k127_1900843_5	469383.Cwoe_4185	6.331e-95	325.0	COG2508@1|root,COG2508@2|Bacteria,2GR38@201174|Actinobacteria	201174|Actinobacteria	QT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158462_k127_1900843_7	1283299.AUKG01000001_gene2871	3.218e-63	224.0	COG3000@1|root,COG3000@2|Bacteria,2ISSM@201174|Actinobacteria,4CQ11@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158462_k127_1907509_0	640081.Dsui_2517	3.615e-83	289.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria	28216|Betaproteobacteria	L	transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158462_k127_1952477_0	410359.Pcal_1868	4.898e-24	102.0	arCOG05874@1|root,arCOG05874@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_1952477_2	410359.Pcal_1867	7.374e-11	64.0	COG3780@1|root,arCOG03156@2157|Archaea	2157|Archaea	L	ATPase involved in replication control Cdc46 Mcm family	-	-	2.7.7.7	ko:K02319,ko:K07332,ko:K07500,ko:K10726	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko02035,ko02044,ko03032	-	-	-	HTH_3,Intein_splicing,LAGLIDADG_3,MCM,MCM_N,MCM_OB,T2SSE
SRR25158462_k127_199205_19	929712.KI912613_gene2660	2.306e-25	123.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria,4CPUR@84995|Rubrobacteria	84995|Rubrobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158462_k127_199205_5	469383.Cwoe_5554	2.172e-116	382.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4CR2R@84995|Rubrobacteria	84995|Rubrobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158462_k127_199205_7	469383.Cwoe_3251	4.131e-91	309.0	COG1372@1|root,COG1533@1|root,COG1372@2|Bacteria,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158462_k127_199205_20	469383.Cwoe_3251	3.204e-21	97.0	COG1372@1|root,COG1533@1|root,COG1372@2|Bacteria,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158462_k127_199205_10	631454.N177_3468	1.106e-66	231.0	28NR0@1|root,2ZBQD@2|Bacteria,1RA2I@1224|Proteobacteria,2U5BA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleoside 2-deoxyribosyltransferase YtoQ	ytoQ	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyri_tr3
SRR25158462_k127_199205_4	1048339.KB913029_gene3712	1.243e-116	395.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158462_k127_199205_16	469383.Cwoe_3152	3.004e-40	158.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_199205_18	469383.Cwoe_3152	2.788e-32	135.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_199205_17	469383.Cwoe_3152	2.781e-38	153.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_199205_15	469383.Cwoe_1281	6.528e-48	175.0	29XHQ@1|root,30J8E@2|Bacteria,2HRAN@201174|Actinobacteria,4CT7J@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_199205_21	1121121.KB894314_gene1544	1.653e-05	53.0	2EQ35@1|root,33HPH@2|Bacteria,1VMY6@1239|Firmicutes,4HRBN@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_199205_13	1121933.AUHH01000009_gene830	3.781e-53	194.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DQP2@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158462_k127_199205_9	1380390.JIAT01000009_gene993	7.37e-74	266.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4CSH9@84995|Rubrobacteria	84995|Rubrobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158462_k127_199205_14	469383.Cwoe_5355	2.661e-50	183.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CSRN@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158462_k127_199205_11	1283299.AUKG01000003_gene189	2.276e-66	234.0	COG0491@1|root,COG0491@2|Bacteria,2GSTF@201174|Actinobacteria,4CQ4G@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_199205_3	1380390.JIAT01000009_gene942	4.097e-131	429.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria,4CRE7@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158462_k127_199205_2	469383.Cwoe_1309	1.786e-169	542.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158462_k127_199205_12	1343740.M271_11730	2.209e-58	213.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph1	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,HAD_2,Hydrolase_like
SRR25158462_k127_199205_6	1172185.KB911509_gene158	4.41e-95	340.0	COG1294@1|root,COG1294@2|Bacteria,2GN42@201174|Actinobacteria,4FZU6@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158462_k127_199205_1	1380347.JNII01000005_gene3218	9.889e-171	548.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4ETMT@85013|Frankiales	201174|Actinobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158462_k127_199205_0	1267533.KB906745_gene60	3.9e-239	745.0	COG0166@1|root,COG0166@2|Bacteria,3Y3HG@57723|Acidobacteria,2JIQE@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the GPI family	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158462_k127_2158816_3	641112.ACOK01000119_gene1415	1.626e-23	101.0	2E4EA@1|root,32Z9I@2|Bacteria,1VG12@1239|Firmicutes,24R4R@186801|Clostridia,3WKRY@541000|Ruminococcaceae	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2158816_0	1304875.JAFZ01000002_gene1	5.761e-33	130.0	2DMHR@1|root,32RMI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2158816_4	1122971.BAME01000208_gene6775	2.157e-11	64.0	2DMHR@1|root,32RMI@2|Bacteria,4NUR9@976|Bacteroidetes,2FT84@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2158816_2	941770.GL622179_gene415	4.458e-28	116.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,4HYZ4@91061|Bacilli,3F78H@33958|Lactobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2158816_1	748671.LCRIS_00440	4.935e-31	123.0	2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2158816_5	498761.HM1_3146	0.0002699	44.0	2DER4@1|root,2ZNXD@2|Bacteria,1W32Q@1239|Firmicutes,24UYB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_3	469383.Cwoe_5268	1.065e-187	593.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CP9U@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158462_k127_220271_20	160799.PBOR_35890	7.471e-29	132.0	29DCJ@1|root,300AD@2|Bacteria,1U1PQ@1239|Firmicutes,4IB67@91061|Bacilli,273RZ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_21	500153.JOEK01000003_gene1080	2.159e-20	97.0	2DUW4@1|root,32UXY@2|Bacteria,2IJWI@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
SRR25158462_k127_220271_23	479431.Namu_2597	1.492e-12	79.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IDNP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_7	710111.FraQA3DRAFT_3377	7.033e-108	360.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4EVS8@85013|Frankiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158462_k127_220271_15	1074488.AGBX01000007_gene1580	2.647e-44	166.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria,4FCU7@85020|Dermabacteraceae	201174|Actinobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158462_k127_220271_16	1306406.ASHX01000001_gene3598	1.052e-40	160.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158462_k127_220271_24	469383.Cwoe_0214	1.562e-11	78.0	2EAM3@1|root,31NNY@2|Bacteria,2HR7U@201174|Actinobacteria,4CT3W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_2	397278.JOJN01000002_gene23	1.676e-191	616.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DPQN@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158462_k127_220271_9	469383.Cwoe_3906	1.862e-77	266.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lpsA1	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2,PGAP1
SRR25158462_k127_220271_10	469383.Cwoe_3906	1.943e-77	266.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lpsA1	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2,PGAP1
SRR25158462_k127_220271_6	469383.Cwoe_5269	1.092e-118	395.0	COG0208@1|root,COG3255@1|root,COG0208@2|Bacteria,COG3255@2|Bacteria,2GK48@201174|Actinobacteria,4CR5N@84995|Rubrobacteria	84995|Rubrobacteria	FI	Ribonucleotide reductase, small chain	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_sm,SCP2
SRR25158462_k127_220271_5	487521.OCU_15590	7.828e-119	398.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,2369H@1762|Mycobacteriaceae	201174|Actinobacteria	J	Belongs to the amidase family	amiB2	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158462_k127_220271_1	469383.Cwoe_1195	2.256e-198	643.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_220271_27	1121022.ABENE_20110	3.261e-05	50.0	COG1476@1|root,COG1476@2|Bacteria,1NPDH@1224|Proteobacteria,2TZJ0@28211|Alphaproteobacteria,2KHGV@204458|Caulobacterales	204458|Caulobacterales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_220271_28	1254432.SCE1572_29140	0.0008835	45.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158462_k127_220271_8	1380390.JIAT01000010_gene4173	1.09e-99	336.0	COG3677@1|root,COG3677@2|Bacteria,2HGBB@201174|Actinobacteria,4CTUD@84995|Rubrobacteria	84995|Rubrobacteria	K	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_22	40215.BBOS01000014_gene2344	2.663e-20	98.0	2E0GI@1|root,32W2H@2|Bacteria,1N29Q@1224|Proteobacteria,1SAIH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_11	205914.HS_0558	5.301e-64	227.0	28I7P@1|root,2Z8AJ@2|Bacteria,1MY0A@1224|Proteobacteria,1RZAQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3800)	rlfA	-	-	-	-	-	-	-	-	-	-	-	DUF3800
SRR25158462_k127_220271_4	469383.Cwoe_1482	7.246e-128	417.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CRPW@84995|Rubrobacteria	84995|Rubrobacteria	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158462_k127_220271_14	1283299.AUKG01000003_gene546	1.83e-58	209.0	COG1309@1|root,COG1309@2|Bacteria,2HQ9V@201174|Actinobacteria,4CRTR@84995|Rubrobacteria	84995|Rubrobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158462_k127_220271_17	1380390.JIAT01000009_gene773	2.152e-32	131.0	2AWFM@1|root,31NBV@2|Bacteria,2HQY5@201174|Actinobacteria,4CSQN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_13	469383.Cwoe_5505	8.838e-59	228.0	COG5305@1|root,COG5305@2|Bacteria,2HPE5@201174|Actinobacteria,4CQS9@84995|Rubrobacteria	84995|Rubrobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158462_k127_220271_0	1283299.AUKG01000003_gene544	0.0	1043.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4CPC3@84995|Rubrobacteria	84995|Rubrobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158462_k127_220271_19	1380390.JIAT01000009_gene776	1.539e-30	130.0	COG0071@1|root,COG0071@2|Bacteria,2HR04@201174|Actinobacteria,4CSTR@84995|Rubrobacteria	84995|Rubrobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158462_k127_220271_25	1380390.JIAT01000009_gene781	5.064e-10	64.0	2AUW4@1|root,31KJJ@2|Bacteria,2HPE0@201174|Actinobacteria,4CQS2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_220271_12	469383.Cwoe_5323	6.043e-64	232.0	COG3000@1|root,COG3000@2|Bacteria,2ISSM@201174|Actinobacteria,4CQ11@84995|Rubrobacteria	84995|Rubrobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
SRR25158462_k127_220271_18	1283299.AUKG01000005_gene39	1.288e-30	126.0	COG2508@1|root,COG2508@2|Bacteria,2GR38@201174|Actinobacteria,4CS4Z@84995|Rubrobacteria	84995|Rubrobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158462_k127_2229711_27	1283299.AUKG01000001_gene1940	1.465e-20	96.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158462_k127_2229711_20	1283299.AUKG01000001_gene3004	5.504e-52	189.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4CU6K@84995|Rubrobacteria	84995|Rubrobacteria	E	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158462_k127_2229711_18	1396141.BATP01000036_gene3855	6.336e-54	194.0	COG0110@1|root,COG0110@2|Bacteria,46XP3@74201|Verrucomicrobia,2IWAD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158462_k127_2229711_26	1283299.AUKG01000001_gene2988	3.926e-22	104.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
SRR25158462_k127_2229711_3	1283299.AUKG01000001_gene2971	7.327e-121	417.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CPXY@84995|Rubrobacteria	84995|Rubrobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158462_k127_2229711_21	33876.JNXY01000014_gene3929	1.729e-47	190.0	COG0438@1|root,COG0438@2|Bacteria,2IN8Y@201174|Actinobacteria,4D9G5@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR25158462_k127_2229711_9	1283299.AUKG01000001_gene2989	1.795e-89	308.0	COG1215@1|root,COG1215@2|Bacteria,2IF59@201174|Actinobacteria,4CT2D@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_2229711_15	1380390.JIAT01000011_gene2885	8.343e-69	269.0	COG0823@1|root,COG1749@1|root,COG2372@1|root,COG2374@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1749@2|Bacteria,COG2372@2|Bacteria,COG2374@2|Bacteria,COG4733@2|Bacteria,2I2X3@201174|Actinobacteria,4CSIX@84995|Rubrobacteria	84995|Rubrobacteria	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,fn3
SRR25158462_k127_2229711_30	797302.Halru_1149	2.118e-09	73.0	COG3979@1|root,COG5276@1|root,arCOG02565@2157|Archaea,arCOG07581@2157|Archaea,2XV6J@28890|Euryarchaeota,23SNQ@183963|Halobacteria	183963|Halobacteria	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158462_k127_2229711_25	1457250.BBMO01000002_gene2838	2.854e-35	158.0	arCOG02420@1|root,arCOG03991@1|root,arCOG02420@2157|Archaea,arCOG03991@2157|Archaea,2Y822@28890|Euryarchaeota	28890|Euryarchaeota	S	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Pilin_N
SRR25158462_k127_2229711_24	1380390.JIAT01000011_gene2882	4.906e-43	178.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2229711_13	1283299.AUKG01000001_gene2981	6.61e-73	278.0	2F4YQ@1|root,33XKJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2229711_19	469383.Cwoe_1560	8.127e-54	201.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_2229711_12	1194165.CAJF01000018_gene3603	1.479e-74	281.0	COG0438@1|root,COG0438@2|Bacteria,2GZMP@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158462_k127_2229711_10	1283299.AUKG01000001_gene2983	1.065e-84	304.0	COG3307@1|root,COG3307@2|Bacteria,2HRT0@201174|Actinobacteria,4CTWA@84995|Rubrobacteria	84995|Rubrobacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2229711_29	685727.REQ_40610	3.795e-19	102.0	COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,4G37N@85025|Nocardiaceae	201174|Actinobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158462_k127_2229711_32	1380355.JNIJ01000020_gene3813	0.0001414	54.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,3JS7U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158462_k127_2229711_22	1380390.JIAT01000014_gene6292	1.553e-46	189.0	COG2885@1|root,COG2885@2|Bacteria,2HENQ@201174|Actinobacteria,4CQR9@84995|Rubrobacteria	84995|Rubrobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2
SRR25158462_k127_2229711_1	1150864.MILUP08_41180	2.342e-137	445.0	COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
SRR25158462_k127_2229711_0	1349820.M707_20920	5.355e-251	792.0	COG0323@1|root,COG0323@2|Bacteria,2IATP@201174|Actinobacteria	201174|Actinobacteria	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
SRR25158462_k127_2229711_28	1380390.JIAT01000002_gene6023	6.253e-20	105.0	COG0515@1|root,COG1470@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.18	ko:K01186,ko:K20276	ko00511,ko00600,ko02024,ko04142,map00511,map00600,map02024,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_3_2,CHB_HEX_C_1,Laminin_G_3,NPCBM_assoc
SRR25158462_k127_2229711_31	1328313.DS2_10227	5.274e-06	58.0	COG2911@1|root,COG3420@1|root,COG2911@2|Bacteria,COG3420@2|Bacteria,1R3SR@1224|Proteobacteria,1RZVM@1236|Gammaproteobacteria,464U5@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Chondroitinase B	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Chondroitinas_B
SRR25158462_k127_2229711_14	2002.JOEQ01000012_gene5594	5.431e-71	254.0	COG0823@1|root,COG0823@2|Bacteria,2GK0R@201174|Actinobacteria	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158462_k127_2229711_6	1283299.AUKG01000001_gene3003	1.934e-102	347.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria,4CQWD@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_2229711_7	1380390.JIAT01000011_gene2880	1.416e-98	346.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158462_k127_2229711_23	1380390.JIAT01000011_gene2879	1.029e-45	185.0	COG0463@1|root,COG0463@2|Bacteria,2IDAM@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158462_k127_2229711_11	357808.RoseRS_1135	8.442e-75	268.0	COG0673@1|root,COG0673@2|Bacteria,2G6Y0@200795|Chloroflexi,376NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158462_k127_2229711_8	697281.Mahau_0358	2.094e-93	317.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,42HP4@68295|Thermoanaerobacterales	186801|Clostridia	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158462_k127_2229711_16	1283299.AUKG01000001_gene2996	2.499e-60	218.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CRCH@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158462_k127_2229711_2	1283299.AUKG01000001_gene2972	1.809e-126	427.0	COG0673@1|root,COG0673@2|Bacteria,2HPZE@201174|Actinobacteria,4CREW@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158462_k127_2229711_17	1283299.AUKG01000001_gene2970	5.434e-58	207.0	COG1595@1|root,COG1595@2|Bacteria,2HRFN@201174|Actinobacteria,4CTEH@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_2229711_5	1429046.RR21198_5493	2.068e-103	346.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4FXWU@85025|Nocardiaceae	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	galE4	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158462_k127_2229711_4	1380390.JIAT01000010_gene4887	1.354e-109	364.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158462_k127_2234240_1	521011.Mpal_1389	1.637e-11	79.0	COG3391@1|root,arCOG02545@1|root,arCOG02545@2157|Archaea,arCOG03563@2157|Archaea	2157|Archaea	P	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,NHL,NosD,PKD
SRR25158462_k127_2234240_0	1283299.AUKG01000001_gene3551	2.545e-45	190.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158462_k127_2337000_0	1112274.KI911560_gene259	1.944e-146	474.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VKD6@28216|Betaproteobacteria,2KNE8@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158462_k127_2394831_2	889378.Spiaf_1960	5.188e-216	680.0	COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes	203691|Spirochaetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158462_k127_2394831_38	290397.Adeh_0224	2.973e-52	199.0	COG3568@1|root,COG3568@2|Bacteria,1N29G@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158462_k127_2394831_43	469383.Cwoe_0906	6.103e-48	186.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158462_k127_2394831_76	1380390.JIAT01000014_gene6069	0.0005558	48.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria,2HSN9@201174|Actinobacteria,4CS57@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C
SRR25158462_k127_2394831_25	1380390.JIAT01000009_gene1519	3.366e-74	256.0	COG0177@1|root,COG0177@2|Bacteria,2HPSY@201174|Actinobacteria,4CR6E@84995|Rubrobacteria	84995|Rubrobacteria	L	FES	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158462_k127_2394831_24	469383.Cwoe_0795	1.246e-75	268.0	COG0596@1|root,COG0596@2|Bacteria,2HTV2@201174|Actinobacteria,4CTBC@84995|Rubrobacteria	84995|Rubrobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158462_k127_2394831_36	1283299.AUKG01000001_gene1467	7.778e-56	204.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria,4CRYZ@84995|Rubrobacteria	84995|Rubrobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158462_k127_2394831_19	469383.Cwoe_0791	2.447e-87	293.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158462_k127_2394831_3	469383.Cwoe_0790	9.129e-200	627.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CQZJ@84995|Rubrobacteria	84995|Rubrobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158462_k127_2394831_10	1283299.AUKG01000001_gene1474	4.597e-119	396.0	COG0438@1|root,COG0613@1|root,COG0438@2|Bacteria,COG0613@2|Bacteria,2HPUE@201174|Actinobacteria,4CR88@84995|Rubrobacteria	84995|Rubrobacteria	M	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
SRR25158462_k127_2394831_18	469383.Cwoe_0788	1.148e-87	313.0	COG1573@1|root,COG1573@2|Bacteria,2HNTA@201174|Actinobacteria,4CQ1J@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158462_k127_2394831_27	1125971.ASJB01000057_gene5301	3.259e-68	237.0	COG2862@1|root,COG2862@2|Bacteria,2IJP5@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
SRR25158462_k127_2394831_44	479434.Sthe_3510	3.13e-47	181.0	COG2141@1|root,COG2141@2|Bacteria,2GB9A@200795|Chloroflexi,27Y8J@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158462_k127_2394831_5	1283299.AUKG01000001_gene1484	1.103e-157	509.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CRR6@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158462_k127_2394831_65	1380390.JIAT01000009_gene1544	1.374e-08	62.0	2AUQB@1|root,31KDA@2|Bacteria,2GX9T@201174|Actinobacteria,4CQM3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_50	1283299.AUKG01000001_gene1490	2.16e-32	140.0	COG3021@1|root,COG3021@2|Bacteria,2HQIN@201174|Actinobacteria,4CS44@84995|Rubrobacteria	84995|Rubrobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158462_k127_2394831_14	469383.Cwoe_0778	8.468e-102	353.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CPYJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158462_k127_2394831_26	929712.KI912613_gene1845	4.176e-72	254.0	COG0625@1|root,COG0625@2|Bacteria,2HBBW@201174|Actinobacteria,4CT8I@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N,GST_N_3
SRR25158462_k127_2394831_15	1380390.JIAT01000013_gene85	1.929e-100	333.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CQIT@84995|Rubrobacteria	84995|Rubrobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158462_k127_2394831_39	1283299.AUKG01000002_gene3862	8.015e-50	188.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158462_k127_2394831_8	1380390.JIAT01000011_gene2856	2.368e-131	435.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CR5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158462_k127_2394831_55	1283299.AUKG01000002_gene4684	5.507e-26	109.0	2AUS7@1|root,31KF8@2|Bacteria,2HPA6@201174|Actinobacteria,4CQNH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
SRR25158462_k127_2394831_35	1173024.KI912151_gene1587	6.003e-56	201.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158462_k127_2394831_28	929712.KI912613_gene2022	2.739e-67	237.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQ3X@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158462_k127_2394831_71	110319.CF8_1856	1.302e-05	55.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4DNBK@85009|Propionibacteriales	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158462_k127_2394831_75	1342302.JASC01000003_gene3595	0.0005214	50.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	intD	GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0008979,GO:0009009,GO:0009987,GO:0015074,GO:0016032,GO:0019042,GO:0019043,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051704,GO:0071704,GO:0075713,GO:0090304,GO:0140097,GO:1901360	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	Phage_integrase
SRR25158462_k127_2394831_57	290399.Arth_4483	1.354e-22	103.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158462_k127_2394831_46	290399.Arth_4482	9.397e-42	174.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-E2_A,Prok-E2_B,Prok-JAB,ThiF
SRR25158462_k127_2394831_56	67356.KL575585_gene8289	1.288e-23	106.0	2DPCE@1|root,331HP@2|Bacteria,2I4SR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_51	710685.MycrhN_3810	1.787e-29	123.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,23E0D@1762|Mycobacteriaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158462_k127_2394831_29	195253.Syn6312_1033	4.45e-66	228.0	arCOG06889@1|root,32RJ7@2|Bacteria	2|Bacteria	S	PFAM MTH538 TIR-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
SRR25158462_k127_2394831_61	469383.Cwoe_2410	2.156e-16	85.0	2C7CU@1|root,33J7G@2|Bacteria,2GWKR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_59	469383.Cwoe_2411	3.5e-20	95.0	2E8MQ@1|root,332Z5@2|Bacteria,2ISX4@201174|Actinobacteria	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158462_k127_2394831_1	1194972.MVAC_23265	0.0	1184.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,2341B@1762|Mycobacteriaceae	201174|Actinobacteria	L	ABC transporter	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158462_k127_2394831_48	1089546.AQUI01000002_gene3178	3.09e-40	153.0	COG1359@1|root,COG1359@2|Bacteria,2GSSA@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_21	477641.MODMU_3790	2.198e-84	284.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4EV4U@85013|Frankiales	201174|Actinobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158462_k127_2394831_58	197221.22295959	7.315e-22	99.0	COG1669@1|root,COG1669@2|Bacteria,1G8GD@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158462_k127_2394831_53	138119.DSY2810	8.018e-28	115.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,24QN5@186801|Clostridia,2635X@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158462_k127_2394831_62	1122134.KB893650_gene1050	5.435e-14	76.0	2EGPH@1|root,33AFM@2|Bacteria,1Q0F4@1224|Proteobacteria,1SQB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_40	469383.Cwoe_0425	8.617e-50	199.0	COG2815@1|root,COG3291@1|root,COG2815@2|Bacteria,COG3291@2|Bacteria,2I9UB@201174|Actinobacteria,4CTSN@84995|Rubrobacteria	84995|Rubrobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SRR25158462_k127_2394831_60	555079.Toce_2178	2.554e-19	91.0	COG1708@1|root,COG1708@2|Bacteria,1VM1R@1239|Firmicutes,24UG9@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158462_k127_2394831_6	378806.STAUR_8277	6.47e-135	440.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42MWV@68525|delta/epsilon subdivisions,2WJJZ@28221|Deltaproteobacteria,2YWKY@29|Myxococcales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24
SRR25158462_k127_2394831_74	1210884.HG799470_gene14444	0.0001442	51.0	COG1595@1|root,COG1595@2|Bacteria,2IZFC@203682|Planctomycetes	203682|Planctomycetes	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_2394831_33	929712.KI912613_gene3706	3.918e-62	222.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4CQRB@84995|Rubrobacteria	84995|Rubrobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158462_k127_2394831_4	196162.Noca_0969	1.993e-196	651.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158462_k127_2394831_16	196162.Noca_0968	6.471e-94	319.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158462_k127_2394831_22	266117.Rxyl_0848	2.405e-83	284.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158462_k127_2394831_13	42256.RradSPS_0734	3.017e-108	387.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	84995|Rubrobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158462_k127_2394831_66	497965.Cyan7822_5523	1.996e-07	56.0	COG1396@1|root,COG1396@2|Bacteria,1GA8S@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_2394831_73	749927.AMED_8672	1.996e-05	51.0	COG0640@1|root,COG0640@2|Bacteria,2IEV0@201174|Actinobacteria,4E462@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_2394831_20	1265310.CCBD010000047_gene2633	6.151e-86	295.0	COG2070@1|root,COG2070@2|Bacteria,2IADG@201174|Actinobacteria,235FT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158462_k127_2394831_69	479432.Sros_0067	1.187e-05	54.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158462_k127_2394831_63	1463857.JOFZ01000004_gene2650	1.536e-13	76.0	COG3794@1|root,COG3794@2|Bacteria,2GS7W@201174|Actinobacteria	201174|Actinobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158462_k127_2394831_41	66373.JOFQ01000018_gene1146	9.981e-50	186.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158462_k127_2394831_23	469383.Cwoe_3564	9.399e-77	267.0	COG3662@1|root,COG3662@2|Bacteria,2II6C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158462_k127_2394831_12	118166.JH976537_gene3016	8.36e-111	377.0	COG0465@1|root,COG0465@2|Bacteria,1G22Z@1117|Cyanobacteria,1H7W7@1150|Oscillatoriales	1117|Cyanobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158462_k127_2394831_31	1380390.JIAT01000014_gene6051	4.582e-65	229.0	COG1716@1|root,COG2197@1|root,COG1716@2|Bacteria,COG2197@2|Bacteria,2IJPV@201174|Actinobacteria,4CR0J@84995|Rubrobacteria	84995|Rubrobacteria	KT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158462_k127_2394831_45	285535.JOEY01000015_gene4211	6.764e-43	177.0	COG1572@1|root,COG2931@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158462_k127_2394831_34	469383.Cwoe_1050	1.653e-57	217.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4CQ3N@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_2394831_42	1283299.AUKG01000002_gene4655	2.118e-49	199.0	COG0596@1|root,COG0596@2|Bacteria,2I2VI@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158462_k127_2394831_9	1458275.AZ34_07520	2.583e-124	413.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,4AC6Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158462_k127_2394831_30	380358.XALC_2497	2.918e-65	247.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,1RRT8@1236|Gammaproteobacteria,1X449@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
SRR25158462_k127_2394831_7	1283299.AUKG01000004_gene1118	3.206e-132	440.0	COG2907@1|root,COG2907@2|Bacteria,2GJMW@201174|Actinobacteria,4CRSU@84995|Rubrobacteria	84995|Rubrobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158462_k127_2394831_11	469383.Cwoe_0729	5.598e-112	377.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.2.1.132	ko:K01233	ko00520,ko01100,map00520,map01100	-	R02833	-	ko00000,ko00001,ko01000	-	-	-	Muraidase,PG_binding_1
SRR25158462_k127_2394831_32	521098.Aaci_2886	2.073e-63	227.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,279TN@186823|Alicyclobacillaceae	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158462_k127_2394831_52	1463820.JOGW01000001_gene5570	1.186e-28	121.0	COG1846@1|root,COG1846@2|Bacteria,2INEU@201174|Actinobacteria	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_37	1283299.AUKG01000002_gene4966	1.201e-55	213.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158462_k127_2394831_0	1237500.ANBA01000001_gene5133	0.0	1275.0	COG1205@1|root,COG1205@2|Bacteria,2GKQ2@201174|Actinobacteria	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158462_k127_2394831_54	1463858.JOHR01000012_gene2321	2.467e-26	126.0	COG2141@1|root,COG2141@2|Bacteria,2IDJK@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_49	1463858.JOHR01000012_gene2320	2.65e-36	149.0	2E2JY@1|root,32XPE@2|Bacteria,2IHJS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2394831_47	1133849.O3I_031870	1.093e-41	159.0	COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4G70R@85025|Nocardiaceae	201174|Actinobacteria	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,NUDIX,Vsr
SRR25158462_k127_2394831_17	1348338.ADILRU_1159	3.239e-93	318.0	COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
SRR25158462_k127_2394831_64	1449347.JQLN01000005_gene4804	8.607e-09	68.0	2DMX8@1|root,32U7B@2|Bacteria,2H3QY@201174|Actinobacteria	201174|Actinobacteria	L	SacI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_SacI
SRR25158462_k127_2394831_67	469383.Cwoe_1036	3.075e-07	52.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,4CTD9@84995|Rubrobacteria	84995|Rubrobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158462_k127_2428247_1	1035191.HMPREF0185_02541	8.162e-171	544.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2KEZY@204458|Caulobacterales	204458|Caulobacterales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158462_k127_2428247_13	580331.Thit_0893	9.538e-25	111.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158462_k127_2428247_4	469383.Cwoe_0800	2.192e-140	454.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CPEG@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158462_k127_2428247_12	1283299.AUKG01000001_gene1457	1.833e-28	130.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CQCY@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158462_k127_2428247_0	1303518.CCALI_00290	0.0	1033.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158462_k127_2428247_10	1380390.JIAT01000012_gene3184	4.75e-49	198.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
SRR25158462_k127_2428247_11	469383.Cwoe_0806	1.144e-30	124.0	COG4274@1|root,COG4274@2|Bacteria,2HR6Q@201174|Actinobacteria,4CT2K@84995|Rubrobacteria	84995|Rubrobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158462_k127_2428247_3	469383.Cwoe_0807	1.717e-149	484.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CP95@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158462_k127_2428247_9	1380390.JIAT01000009_gene1491	2.911e-54	195.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CQ7C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158462_k127_2428247_2	929712.KI912613_gene1927	7.857e-169	554.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4CPI0@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158462_k127_2428247_15	1122939.ATUD01000022_gene3661	9.651e-15	87.0	2CFVN@1|root,2ZV9N@2|Bacteria,2GV11@201174|Actinobacteria,4CTQC@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2428247_5	1380390.JIAT01000009_gene2027	6.513e-115	387.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CPQ8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158462_k127_2428247_6	1283299.AUKG01000001_gene1437	1.283e-114	380.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CPBJ@84995|Rubrobacteria	84995|Rubrobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158462_k127_2428247_14	469383.Cwoe_0820	1.087e-22	109.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR25158462_k127_2428247_8	1122939.ATUD01000001_gene336	7.894e-78	272.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4CPW1@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158462_k127_2428247_7	1380390.JIAT01000009_gene1483	6.112e-86	297.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4CP9W@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158462_k127_2444892_1	1502852.FG94_02611	5.327e-133	440.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,2VIE4@28216|Betaproteobacteria,474WY@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR25158462_k127_2444892_0	365046.Rta_27580	2.848e-236	741.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,2VKVU@28216|Betaproteobacteria,4AA8S@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
SRR25158462_k127_2486503_1	469383.Cwoe_1946	3.419e-11	66.0	COG0346@1|root,COG0346@2|Bacteria,2IM80@201174|Actinobacteria,4CTXK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_2486503_0	1380391.JIAS01000004_gene2960	1.938e-62	224.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,2JP86@204441|Rhodospirillales	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158462_k127_2500724_3	1121468.AUBR01000006_gene373	1.737e-121	397.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,42EUU@68295|Thermoanaerobacterales	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158462_k127_2500724_5	67373.JOBF01000004_gene982	3.901e-09	67.0	COG1475@1|root,COG1475@2|Bacteria,2IHQK@201174|Actinobacteria	201174|Actinobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158462_k127_2500724_2	1283299.AUKG01000002_gene4628	1.74e-139	451.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CP79@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158462_k127_2500724_4	929712.KI912613_gene3346	1.173e-55	196.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158462_k127_2500724_1	469383.Cwoe_3754	1.836e-201	638.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CP8Z@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158462_k127_2500724_0	469383.Cwoe_3753	6.097e-225	704.0	COG1003@1|root,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4CPH8@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
SRR25158462_k127_2561406_2	469383.Cwoe_2875	1.879e-120	392.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CPEX@84995|Rubrobacteria	84995|Rubrobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158462_k127_2561406_7	1380356.JNIK01000003_gene1217	4.804e-07	57.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158462_k127_2561406_5	469383.Cwoe_3472	5.719e-67	235.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158462_k127_2561406_4	1283299.AUKG01000002_gene4675	1.427e-81	281.0	COG2197@1|root,COG2197@2|Bacteria,2HQF1@201174|Actinobacteria,4CRZT@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158462_k127_2561406_3	1380390.JIAT01000010_gene4195	1.581e-101	349.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CSC0@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158462_k127_2561406_6	1283299.AUKG01000002_gene4673	1.093e-36	143.0	COG2197@1|root,COG2197@2|Bacteria,2I5RT@201174|Actinobacteria,4CST9@84995|Rubrobacteria	84995|Rubrobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158462_k127_2561406_1	1380390.JIAT01000015_gene5825	1.214e-234	752.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158462_k127_2561406_0	469383.Cwoe_2882	0.0	1419.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158462_k127_2586608_0	1185652.USDA257_c30680	7.701e-108	362.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2UEQQ@28211|Alphaproteobacteria,4BC7V@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,rve,rve_3
SRR25158462_k127_2627065_12	469383.Cwoe_1160	8.59e-106	350.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CPCM@84995|Rubrobacteria	84995|Rubrobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158462_k127_2627065_43	1283299.AUKG01000003_gene295	3.337e-37	144.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CQIE@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158462_k127_2627065_38	469383.Cwoe_1158	5.368e-42	169.0	COG0839@1|root,COG0839@2|Bacteria,2HRQ0@201174|Actinobacteria,4CTSA@84995|Rubrobacteria	84995|Rubrobacteria	C	plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158462_k127_2627065_15	469383.Cwoe_1157	9.467e-94	311.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CQRQ@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158462_k127_2627065_17	671143.DAMO_2695	7.039e-92	317.0	COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158462_k127_2627065_1	469383.Cwoe_1155	1.615e-250	822.0	COG1034@1|root,COG1153@1|root,COG1034@2|Bacteria,COG1153@2|Bacteria,2GJGX@201174|Actinobacteria,4CR3F@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158462_k127_2627065_7	469383.Cwoe_1154	5.185e-173	564.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4CR2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158462_k127_2627065_33	1283299.AUKG01000003_gene301	3.855e-49	196.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CP9Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158462_k127_2627065_6	469383.Cwoe_1152	5.615e-184	584.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CP64@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158462_k127_2627065_35	469383.Cwoe_1151	1.692e-45	169.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CQ8D@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158462_k127_2627065_30	880072.Desac_2114	8.204e-55	205.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WN9U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3354	Oxidored_q6
SRR25158462_k127_2627065_44	1283299.AUKG01000003_gene305	1.554e-35	139.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CQ6Q@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158462_k127_2627065_45	469383.Cwoe_1148	2.099e-33	134.0	2BGA2@1|root,32A7H@2|Bacteria,2HTT4@201174|Actinobacteria,4CT2Y@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2627065_39	258533.BN977_03152	1.707e-39	151.0	2AJIH@1|root,31A5A@2|Bacteria,2IHK0@201174|Actinobacteria,239TW@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158462_k127_2627065_46	1283299.AUKG01000003_gene307	1.099e-32	147.0	COG1853@1|root,COG1853@2|Bacteria,2HP7U@201174|Actinobacteria,4CRWN@84995|Rubrobacteria	84995|Rubrobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158462_k127_2627065_47	469383.Cwoe_1146	1.139e-23	112.0	COG2010@1|root,COG2010@2|Bacteria,2HQT0@201174|Actinobacteria,4CSHK@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158462_k127_2627065_9	929712.KI912613_gene2421	1.206e-137	449.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CPM3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158462_k127_2627065_42	926550.CLDAP_28540	1.104e-37	149.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158462_k127_2627065_31	1128427.KB904821_gene3352	2.909e-53	196.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1HB1V@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158462_k127_2627065_48	42256.RradSPS_3134	6.729e-19	93.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4CQKG@84995|Rubrobacteria	84995|Rubrobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158462_k127_2627065_19	1206737.BAGF01000081_gene5192	1.278e-82	283.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4FU6N@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158462_k127_2627065_20	644283.Micau_2704	1.415e-82	299.0	COG0477@1|root,COG0477@2|Bacteria,2I4Y7@201174|Actinobacteria,4DFI9@85008|Micromonosporales	201174|Actinobacteria	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_2627065_34	469383.Cwoe_3268	1.379e-45	174.0	COG0647@1|root,COG0647@2|Bacteria,2HG8I@201174|Actinobacteria,4CTX4@84995|Rubrobacteria	84995|Rubrobacteria	G	HAD-superfamily hydrolase, subfamily IIA	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158462_k127_2627065_13	1380390.JIAT01000010_gene4197	9.918e-101	333.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158462_k127_2627065_4	469383.Cwoe_3715	4.216e-203	661.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158462_k127_2627065_16	1089545.KB913037_gene4011	5.869e-92	314.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4DYGY@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158462_k127_2627065_8	1122939.ATUD01000001_gene62	1.505e-142	465.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CPQ8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158462_k127_2627065_51	469383.Cwoe_1705	3.374e-09	63.0	2A614@1|root,30UTC@2|Bacteria,2HRUT@201174|Actinobacteria,4CTY7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2627065_0	469383.Cwoe_5426	0.0	1426.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158462_k127_2627065_24	1122939.ATUD01000010_gene2889	8.417e-64	228.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CQJI@84995|Rubrobacteria	84995|Rubrobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158462_k127_2627065_32	1380390.JIAT01000009_gene1922	3.697e-49	183.0	COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4CQI6@84995|Rubrobacteria	84995|Rubrobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158462_k127_2627065_37	1283299.AUKG01000001_gene1896	2.929e-45	171.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4CS74@84995|Rubrobacteria	84995|Rubrobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158462_k127_2627065_49	926554.KI912671_gene194	4.933e-17	94.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158462_k127_2627065_10	1380390.JIAT01000009_gene1911	1.519e-121	394.0	COG1648@1|root,COG1648@2|Bacteria,2GTES@201174|Actinobacteria,4CQK2@84995|Rubrobacteria	84995|Rubrobacteria	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
SRR25158462_k127_2627065_28	40571.JOEA01000017_gene649	4.81e-61	220.0	28SI0@1|root,2ZEUB@2|Bacteria,2GNT0@201174|Actinobacteria,4E5AA@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR25158462_k127_2627065_29	211114.JOEF01000037_gene6907	1.239e-60	215.0	COG1309@1|root,COG1309@2|Bacteria,2HMJ5@201174|Actinobacteria,4E47V@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_2627065_11	1380390.JIAT01000009_gene2189	1.743e-111	368.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4CRA0@84995|Rubrobacteria	84995|Rubrobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158462_k127_2627065_5	266117.Rxyl_1964	4.103e-200	649.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2GJU7@201174|Actinobacteria,4CPD0@84995|Rubrobacteria	84995|Rubrobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158462_k127_2627065_40	1380390.JIAT01000009_gene2260	3.658e-39	169.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CQ6G@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158462_k127_2627065_21	469383.Cwoe_5416	1.101e-72	258.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CQDV@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158462_k127_2627065_52	1283287.KB822576_gene3942	3.864e-07	64.0	COG2456@1|root,COG2456@2|Bacteria,2GQZ0@201174|Actinobacteria,4DWB6@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
SRR25158462_k127_2627065_27	935845.JADQ01000032_gene1332	1.172e-61	221.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,4HDKY@91061|Bacilli,26U9S@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl transferase family 2	ycbB	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
SRR25158462_k127_2627065_36	1192034.CAP_3332	1.985e-45	181.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2YY2P@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158462_k127_2627065_23	266117.Rxyl_0378	6.402e-65	233.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CPX6@84995|Rubrobacteria	84995|Rubrobacteria	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_2627065_14	469383.Cwoe_5374	9.442e-94	311.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CR9W@84995|Rubrobacteria	84995|Rubrobacteria	OU	Clp protease	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158462_k127_2627065_26	1380390.JIAT01000009_gene2046	8.359e-62	227.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,4CPYU@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	-	-	-	-	-	-	-	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158462_k127_2627065_2	469383.Cwoe_4828	1.028e-226	719.0	28JQV@1|root,2Z9GM@2|Bacteria,2H335@201174|Actinobacteria,4CPRQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2627065_25	1283299.AUKG01000002_gene3648	2.963e-62	222.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4CRRD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158462_k127_2627065_41	469383.Cwoe_0449	5.809e-39	153.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4CTPZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158462_k127_2627065_22	1283299.AUKG01000002_gene4560	1.083e-65	239.0	COG0476@1|root,COG0476@2|Bacteria,2HGW4@201174|Actinobacteria	201174|Actinobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SRR25158462_k127_2627065_18	469383.Cwoe_5791	1.476e-90	314.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158462_k127_2627065_50	469383.Cwoe_1847	5.583e-12	78.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin_2
SRR25158462_k127_2627065_3	1283299.AUKG01000002_gene4633	1.362e-203	663.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CRS8@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158462_k127_2718619_78	1283299.AUKG01000001_gene2083	1.304e-08	59.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2718619_24	469383.Cwoe_2429	5.68e-156	506.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,4CQ9I@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158462_k127_2718619_3	1380393.JHVP01000014_gene4738	2.213e-256	825.0	COG0365@1|root,COG3319@1|root,COG0365@2|Bacteria,COG3319@2|Bacteria,2GM20@201174|Actinobacteria,4ERUI@85013|Frankiales	201174|Actinobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C,PP-binding,Thioesterase
SRR25158462_k127_2718619_20	1122939.ATUD01000001_gene554	4.362e-166	530.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4CSKS@84995|Rubrobacteria	84995|Rubrobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158462_k127_2718619_71	485913.Krac_8547	3.822e-18	86.0	2E3KN@1|root,32YIY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
SRR25158462_k127_2718619_85	1206729.BAFZ01000036_gene4779	0.0005343	46.0	COG0222@1|root,COG0222@2|Bacteria,2HS8Z@201174|Actinobacteria,4G3UI@85025|Nocardiaceae	201174|Actinobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L12
SRR25158462_k127_2718619_80	216591.BCAL2560	2.535e-06	57.0	COG1476@1|root,COG1476@2|Bacteria,1RGXJ@1224|Proteobacteria,2VV0E@28216|Betaproteobacteria,1KAV9@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_2718619_70	492774.JQMB01000015_gene1760	2.089e-19	104.0	COG0454@1|root,COG0456@2|Bacteria,1NKFC@1224|Proteobacteria,2UK8V@28211|Alphaproteobacteria,4BB7E@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2718619_14	469383.Cwoe_4949	6.216e-178	569.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CSAZ@84995|Rubrobacteria	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158462_k127_2718619_53	557599.MKAN_12225	4.144e-63	222.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,238MB@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_2718619_52	469383.Cwoe_2707	7.164e-66	227.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4CT1R@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158462_k127_2718619_5	1283299.AUKG01000002_gene4795	1.754e-242	765.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CPK9@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158462_k127_2718619_49	469383.Cwoe_3622	1.037e-80	274.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CQ6T@84995|Rubrobacteria	84995|Rubrobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158462_k127_2718619_36	1380390.JIAT01000014_gene6290	2.306e-119	393.0	COG0381@1|root,COG0381@2|Bacteria,2GJWS@201174|Actinobacteria,4CTCM@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SRR25158462_k127_2718619_73	469383.Cwoe_3620	3.198e-16	92.0	COG0291@1|root,COG0291@2|Bacteria,2HPDV@201174|Actinobacteria,4CQRX@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158462_k127_2718619_64	1384484.AEQU_0865	6.82e-36	144.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4CVXQ@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158462_k127_2718619_61	929712.KI912613_gene4021	1.063e-44	171.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CPWM@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA rRNA methyltransferase, SpoU	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158462_k127_2718619_26	469383.Cwoe_3617	5.694e-148	475.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CPUG@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158462_k127_2718619_4	1380390.JIAT01000010_gene4417	8.56e-248	795.0	COG0072@1|root,COG0072@2|Bacteria,2GMFD@201174|Actinobacteria,4CP7V@84995|Rubrobacteria	84995|Rubrobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158462_k127_2718619_39	1380390.JIAT01000010_gene4418	4.72e-112	372.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CPXE@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158462_k127_2718619_47	469383.Cwoe_3614	5.38e-94	334.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CPB9@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158462_k127_2718619_34	469383.Cwoe_3613	8.073e-123	400.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CPHD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158462_k127_2718619_44	1089553.Tph_c25450	1.643e-100	353.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,42F28@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158462_k127_2718619_7	469383.Cwoe_3610	2.135e-228	712.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CPRP@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158462_k127_2718619_69	1283299.AUKG01000003_gene334	1.438e-19	102.0	COG4942@1|root,COG4942@2|Bacteria,2HNNM@201174|Actinobacteria,4CPT2@84995|Rubrobacteria	84995|Rubrobacteria	D	Transglycosylase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglycosylas
SRR25158462_k127_2718619_0	1122939.ATUD01000004_gene3875	0.0	1360.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CP98@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158462_k127_2718619_9	1380390.JIAT01000013_gene68	7.491e-224	702.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4CPS1@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_2718619_42	469383.Cwoe_3605	4.893e-103	343.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CP9J@84995|Rubrobacteria	84995|Rubrobacteria	L	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158462_k127_2718619_18	469383.Cwoe_3604	2.142e-174	561.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158462_k127_2718619_40	469383.Cwoe_3603	2.175e-108	361.0	COG1639@1|root,COG2197@1|root,COG1639@2|Bacteria,COG2197@2|Bacteria,2HBP2@201174|Actinobacteria,4CREZ@84995|Rubrobacteria	84995|Rubrobacteria	KT	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HDOD
SRR25158462_k127_2718619_79	29581.BW37_00709	2.926e-07	61.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158462_k127_2718619_63	469383.Cwoe_3601	1.253e-36	142.0	COG1959@1|root,COG1959@2|Bacteria,2HNE1@201174|Actinobacteria,4CQQM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158462_k127_2718619_86	1216976.AX27061_3972	0.0008368	51.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2VK36@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158462_k127_2718619_72	208439.AJAP_22955	1.251e-17	94.0	COG0823@1|root,COG2304@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,2GMNT@201174|Actinobacteria,4DXHJ@85010|Pseudonocardiales	201174|Actinobacteria	U	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PD40,VWA
SRR25158462_k127_2718619_38	525368.HMPREF0591_2208	5.028e-117	383.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,236GV@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158462_k127_2718619_45	1380390.JIAT01000010_gene4444	1.124e-99	330.0	COG1045@1|root,COG1045@2|Bacteria,2IHW5@201174|Actinobacteria,4CRBB@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
SRR25158462_k127_2718619_2	469383.Cwoe_3589	1.388e-270	859.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158462_k127_2718619_43	469383.Cwoe_3588	1.905e-102	340.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CPTY@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158462_k127_2718619_84	469383.Cwoe_1652	0.0003605	50.0	2B0SC@1|root,31T4Q@2|Bacteria,2HQ8T@201174|Actinobacteria,4CRSP@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2718619_48	1299327.I546_0862	3.405e-87	312.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria,23F02@1762|Mycobacteriaceae	201174|Actinobacteria	E	oxidoreductase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
SRR25158462_k127_2718619_67	1122939.ATUD01000004_gene3885	1.631e-26	112.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4CQK8@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158462_k127_2718619_13	1283299.AUKG01000002_gene4839	1.476e-185	596.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CPBB@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158462_k127_2718619_12	469383.Cwoe_3584	3.011e-187	599.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CP9F@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158462_k127_2718619_22	1283299.AUKG01000004_gene1220	1.194e-162	522.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4CPW0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158462_k127_2718619_82	40571.JOEA01000041_gene4655	8.986e-05	55.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria,4EDJP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158462_k127_2718619_19	1283299.AUKG01000002_gene4582	5.427e-168	543.0	COG4102@1|root,COG4102@2|Bacteria,2GJWB@201174|Actinobacteria,4CS10@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158462_k127_2718619_23	1283299.AUKG01000002_gene4581	2.356e-160	521.0	COG5267@1|root,COG5267@2|Bacteria,2I8YT@201174|Actinobacteria,4CP8T@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158462_k127_2718619_68	469383.Cwoe_3581	2.309e-21	96.0	2B7VA@1|root,32124@2|Bacteria,2HRN3@201174|Actinobacteria,4CTQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2718619_35	285514.JNWO01000003_gene7014	1.621e-119	390.0	COG1073@1|root,COG1073@2|Bacteria,2I345@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158462_k127_2718619_54	266117.Rxyl_1238	4.389e-62	242.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4CU1H@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_2718619_62	1122939.ATUD01000004_gene3840	8.964e-38	158.0	29YC3@1|root,30K6G@2|Bacteria,2I7A8@201174|Actinobacteria,4CTY9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2718619_66	929712.KI912613_gene4029	6.637e-31	138.0	29YC3@1|root,30K6G@2|Bacteria,2I7A8@201174|Actinobacteria,4CTY9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2718619_15	479434.Sthe_2765	1.916e-177	563.0	COG0451@1|root,COG0451@2|Bacteria,2G5M4@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158462_k127_2718619_1	469383.Cwoe_3580	4.301e-271	844.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CPN4@84995|Rubrobacteria	84995|Rubrobacteria	E	Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158462_k127_2718619_28	469383.Cwoe_3578	1.291e-144	473.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CQEB@84995|Rubrobacteria	84995|Rubrobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158462_k127_2718619_74	1121939.L861_03415	3.804e-15	87.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XITW@135619|Oceanospirillales	135619|Oceanospirillales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158462_k127_2718619_33	479434.Sthe_3024	4.376e-127	426.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,27XZC@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRR25158462_k127_2718619_65	1382306.JNIM01000001_gene1684	4.197e-35	147.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi	200795|Chloroflexi	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158462_k127_2718619_46	1283299.AUKG01000002_gene4860	2.33e-95	337.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CQ7T@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158462_k127_2718619_29	1380390.JIAT01000010_gene4471	1.752e-144	468.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4CPAK@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158462_k127_2718619_41	309801.trd_A0308	6.687e-107	375.0	COG0318@1|root,COG0318@2|Bacteria,2G7PF@200795|Chloroflexi,27XJD@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158462_k127_2718619_27	1380390.JIAT01000010_gene4476	2.496e-147	474.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CPA6@84995|Rubrobacteria	84995|Rubrobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158462_k127_2718619_59	469383.Cwoe_1589	9.051e-46	171.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_2718619_60	1048339.KB913029_gene1869	9.82e-46	173.0	2DPKA@1|root,332H3@2|Bacteria,2I2YH@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158462_k127_2718619_17	2074.JNYD01000036_gene5361	7.912e-175	555.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4DY92@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158462_k127_2718619_11	469383.Cwoe_3561	7.091e-190	624.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CP5W@84995|Rubrobacteria	84995|Rubrobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158462_k127_2718619_77	1463909.KL585963_gene4904	4.399e-13	77.0	COG2931@1|root,COG2931@2|Bacteria,2IGYS@201174|Actinobacteria	201174|Actinobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158462_k127_2718619_30	1279017.AQYJ01000029_gene3571	6.148e-141	461.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,1RPIM@1236|Gammaproteobacteria,46DF1@72275|Alteromonadaceae	1236|Gammaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_2718619_8	469383.Cwoe_3559	1.806e-227	719.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CP5R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158462_k127_2718619_58	1283299.AUKG01000001_gene1940	5.073e-48	184.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158462_k127_2718619_50	1380390.JIAT01000010_gene4493	3.134e-72	249.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GN0H@201174|Actinobacteria,4CQKX@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158462_k127_2718619_6	469383.Cwoe_3550	2.226e-232	725.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CPQW@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158462_k127_2718619_56	1380390.JIAT01000010_gene4495	2.523e-61	235.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CQ8R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158462_k127_2718619_51	929712.KI912613_gene3955	1.392e-71	253.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4CQ34@84995|Rubrobacteria	84995|Rubrobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
SRR25158462_k127_2718619_31	469383.Cwoe_3548	5.102e-140	453.0	COG0473@1|root,COG0473@2|Bacteria,2HABY@201174|Actinobacteria,4CPBV@84995|Rubrobacteria	84995|Rubrobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158462_k127_2718619_81	1380390.JIAT01000012_gene3310	5.591e-06	57.0	29YC7@1|root,30K6K@2|Bacteria,2HRCJ@201174|Actinobacteria,4CTA2@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2718619_32	1380390.JIAT01000010_gene4499	6.352e-139	448.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158462_k127_2718619_10	469383.Cwoe_3546	1.382e-202	649.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CPIA@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158462_k127_2718619_37	469383.Cwoe_3545	6.779e-118	413.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4CR4P@84995|Rubrobacteria	84995|Rubrobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158462_k127_2718619_21	469383.Cwoe_3544	6.127e-164	527.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CP8S@84995|Rubrobacteria	84995|Rubrobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158462_k127_2718619_55	469383.Cwoe_3543	7.538e-62	221.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4CQEI@84995|Rubrobacteria	84995|Rubrobacteria	L	Methylpurine-DNA glycosylase (MPG)	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158462_k127_2718619_16	469383.Cwoe_3542	7.682e-176	578.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158462_k127_2718619_25	469383.Cwoe_3541	2.647e-153	499.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CPR4@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158462_k127_2718619_76	1193181.BN10_1300016	2.026e-13	73.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2744817_4	194867.ALBQ01000011_gene29	5.503e-150	482.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2K11Z@204457|Sphingomonadales	204457|Sphingomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158462_k127_2744817_8	469383.Cwoe_5748	3.735e-59	214.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CPKG@84995|Rubrobacteria	84995|Rubrobacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRR25158462_k127_2744817_12	469383.Cwoe_5372	6.336e-09	59.0	2C56H@1|root,2ZDSA@2|Bacteria,2HCD2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2744817_7	91464.S7335_4912	3.811e-70	241.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1GZWS@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158462_k127_2744817_5	935948.KE386494_gene467	3.704e-126	413.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,249ZJ@186801|Clostridia,42FX2@68295|Thermoanaerobacterales	186801|Clostridia	P	PUA-like domain	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158462_k127_2744817_6	469383.Cwoe_5533	7.932e-75	258.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4CQ9K@84995|Rubrobacteria	84995|Rubrobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158462_k127_2744817_0	469383.Cwoe_5531	7.166e-295	915.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158462_k127_2744817_11	1122939.ATUD01000009_gene3122	5.235e-26	112.0	COG0607@1|root,COG0607@2|Bacteria,2HFZ6@201174|Actinobacteria,4CQP4@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158462_k127_2744817_13	670292.JH26_07565	0.0001062	51.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2UFCS@28211|Alphaproteobacteria,1JWI0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158462_k127_2744817_9	469383.Cwoe_1506	6.478e-41	164.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_2744817_10	935866.JAER01000001_gene2673	4.5e-33	147.0	COG2931@1|root,COG2931@2|Bacteria,2GKS7@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
SRR25158462_k127_2744817_1	1122939.ATUD01000015_gene945	8.208e-209	657.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPTR@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158462_k127_2744817_2	469383.Cwoe_1334	5.539e-176	562.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4CRZC@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158462_k127_2744817_3	1283299.AUKG01000001_gene2621	2.895e-164	531.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria,4CRKT@84995|Rubrobacteria	84995|Rubrobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRR25158462_k127_2833822_0	3694.POPTR_0009s00520.1	3.569e-73	247.0	KOG1075@1|root,KOG1075@2759|Eukaryota	2759|Eukaryota	E	Ribonuclease H protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4283,RVT_1,zf-CCHC_4,zf-RVT
SRR25158462_k127_2833822_5	3880.AET02208	8.051e-26	109.0	COG0115@1|root,KOG0975@2759|Eukaryota	2759|Eukaryota	E	branched-chain-amino-acid transaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2833822_4	104355.XP_007871309.1	4.911e-36	136.0	2E1I0@1|root,2S8UZ@2759|Eukaryota,3A9DK@33154|Opisthokonta,3Q6KM@4751|Fungi,3V5DS@5204|Basidiomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2833822_3	29875.EHK21457	5.731e-42	154.0	2CUCX@1|root,2RKS6@2759|Eukaryota,38QET@33154|Opisthokonta,3PS8M@4751|Fungi,3R19A@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2833822_1	3712.Bo01607s020.1	1.556e-51	186.0	2BG5J@1|root,2S18N@2759|Eukaryota,38A4I@33090|Viridiplantae,3GZ6Z@35493|Streptophyta,3I0N1@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2833822_2	63577.G9NL02	1.73e-43	158.0	2CYEG@1|root,2S3VE@2759|Eukaryota,39JDY@33154|Opisthokonta,3Q3QK@4751|Fungi,3QXDC@4890|Ascomycota,21SD8@147550|Sordariomycetes,3TUYA@5125|Hypocreales,3U4QQ@5129|Hypocreaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2846009_0	1283299.AUKG01000001_gene1591	1.011e-43	177.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158462_k127_2853659_9	1054860.KB913030_gene194	8.512e-59	207.0	COG5483@1|root,COG5483@2|Bacteria,2IFJK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158462_k127_2853659_14	298654.FraEuI1c_3985	1.615e-10	65.0	2DRBI@1|root,33B4D@2|Bacteria,2GWXK@201174|Actinobacteria,4ETJ0@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2853659_10	290397.Adeh_1214	1.522e-57	220.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,42RB3@68525|delta/epsilon subdivisions,2WMW4@28221|Deltaproteobacteria,2Z183@29|Myxococcales	28221|Deltaproteobacteria	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
SRR25158462_k127_2853659_13	469383.Cwoe_5863	1.046e-24	119.0	COG0671@1|root,COG0671@2|Bacteria,2IIA1@201174|Actinobacteria,4CQUT@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158462_k127_2853659_4	469383.Cwoe_5862	1.838e-129	422.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CP8W@84995|Rubrobacteria	84995|Rubrobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158462_k127_2853659_12	1283299.AUKG01000002_gene4564	1.005e-28	123.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_2853659_5	469383.Cwoe_4154	5.181e-108	359.0	2CDI5@1|root,2Z7ZQ@2|Bacteria,2I8FG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2853659_8	1120949.KB903356_gene8737	2.302e-71	252.0	COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4D95I@85008|Micromonosporales	201174|Actinobacteria	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158462_k127_2853659_7	469383.Cwoe_3325	1.055e-71	258.0	COG2385@1|root,COG2385@2|Bacteria,2ID9T@201174|Actinobacteria,4CPMQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158462_k127_2853659_3	471852.Tcur_0327	3.314e-164	531.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EHQQ@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158462_k127_2853659_6	2045.KR76_18105	1.942e-80	291.0	COG1409@1|root,COG1409@2|Bacteria,2GK31@201174|Actinobacteria,4DN1J@85009|Propionibacteriales	201174|Actinobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158462_k127_2853659_1	1122939.ATUD01000014_gene1067	1.639e-184	586.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CPK3@84995|Rubrobacteria	84995|Rubrobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158462_k127_2853659_11	1380390.JIAT01000012_gene3304	4.919e-29	128.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4CU47@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158462_k127_2853659_2	253839.SSNG_06088	3.835e-173	563.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158462_k127_2853659_0	114615.BRADO2247	1.24e-246	782.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,3JUXZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8
SRR25158462_k127_2871530_65	469383.Cwoe_2561	1.398e-07	61.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_2871530_5	469383.Cwoe_2866	1.581e-199	632.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158462_k127_2871530_29	469383.Cwoe_2865	1.38e-83	286.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158462_k127_2871530_24	266117.Rxyl_1173	1.685e-103	347.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158462_k127_2871530_27	266117.Rxyl_1175	4.032e-90	308.0	COG1840@1|root,COG1840@2|Bacteria,2HRRI@201174|Actinobacteria,4CTU6@84995|Rubrobacteria	84995|Rubrobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158462_k127_2871530_14	266117.Rxyl_1174	2.424e-146	486.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158462_k127_2871530_49	1122939.ATUD01000002_gene1153	8.348e-43	174.0	COG1807@1|root,COG1807@2|Bacteria,2HJTU@201174|Actinobacteria,4CPVS@84995|Rubrobacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158462_k127_2871530_8	1380390.JIAT01000014_gene6281	2.106e-178	571.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4CQXX@84995|Rubrobacteria	84995|Rubrobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158462_k127_2871530_47	1379270.AUXF01000001_gene2084	4.281e-51	193.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158462_k127_2871530_70	227882.SAV_832	6.854e-05	56.0	COG0673@1|root,COG0673@2|Bacteria,2ID72@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158462_k127_2871530_38	1089551.KE386572_gene4426	1.34e-64	241.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,2U12I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158462_k127_2871530_60	1247963.JPHU01000002_gene2496	1.215e-24	118.0	COG1216@1|root,COG1216@2|Bacteria,1R5GW@1224|Proteobacteria,2TTEN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158462_k127_2871530_18	929712.KI912613_gene2806	4.981e-126	411.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4CPGX@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158462_k127_2871530_37	1245471.PCA10_26370	7.785e-68	240.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,1S7AD@1236|Gammaproteobacteria,1YIQQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158462_k127_2871530_36	1283299.AUKG01000004_gene1189	3.642e-72	252.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4CPX0@84995|Rubrobacteria	84995|Rubrobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158462_k127_2871530_7	469383.Cwoe_2859	3.319e-182	586.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CP72@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158462_k127_2871530_39	929712.KI912613_gene4379	2.674e-62	222.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CQBZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158462_k127_2871530_28	1380390.JIAT01000016_gene5611	2.117e-87	323.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158462_k127_2871530_32	929712.KI912613_gene4380	5.161e-80	274.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4CPUD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the TrpC family	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158462_k127_2871530_22	1380390.JIAT01000016_gene5613	1.149e-111	372.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CP6K@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158462_k127_2871530_33	1283299.AUKG01000004_gene1196	1.422e-79	269.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4CPX3@84995|Rubrobacteria	84995|Rubrobacteria	EH	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158462_k127_2871530_6	1122939.ATUD01000002_gene1440	1.144e-187	599.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CPNJ@84995|Rubrobacteria	84995|Rubrobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158462_k127_2871530_40	1122939.ATUD01000002_gene1439	2.272e-61	220.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CQAR@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR25158462_k127_2871530_20	469383.Cwoe_2851	2.357e-116	383.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CPY3@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158462_k127_2871530_55	1122939.ATUD01000002_gene1435	5.69e-34	148.0	COG0319@1|root,COG0319@2|Bacteria,2HN3K@201174|Actinobacteria,4CQHV@84995|Rubrobacteria	84995|Rubrobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158462_k127_2871530_12	469383.Cwoe_2849	2.626e-150	481.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CPBK@84995|Rubrobacteria	84995|Rubrobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158462_k127_2871530_53	469383.Cwoe_2848	1.327e-39	153.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4CQJX@84995|Rubrobacteria	84995|Rubrobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158462_k127_2871530_30	469383.Cwoe_1865	2.837e-83	286.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CQ0N@84995|Rubrobacteria	84995|Rubrobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158462_k127_2871530_31	1283299.AUKG01000004_gene1223	9.77e-82	280.0	COG2264@1|root,COG2264@2|Bacteria,2GW3S@201174|Actinobacteria,4CP8H@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158462_k127_2871530_17	469383.Cwoe_2843	1.464e-137	446.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CP6R@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158462_k127_2871530_25	1380390.JIAT01000016_gene5635	1.891e-100	338.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CP6H@84995|Rubrobacteria	84995|Rubrobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158462_k127_2871530_54	1380390.JIAT01000016_gene5636	1.507e-38	147.0	COG2030@1|root,COG2030@2|Bacteria,2HR1S@201174|Actinobacteria,4CSW6@84995|Rubrobacteria	84995|Rubrobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158462_k127_2871530_51	1283299.AUKG01000004_gene1228	1.075e-41	172.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4CSAG@84995|Rubrobacteria	84995|Rubrobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158462_k127_2871530_2	1380390.JIAT01000016_gene5643	1.18e-281	879.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CP62@84995|Rubrobacteria	84995|Rubrobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158462_k127_2871530_11	469383.Cwoe_2836	2.339e-168	545.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CQCB@84995|Rubrobacteria	84995|Rubrobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158462_k127_2871530_62	1380390.JIAT01000016_gene5646	2.062e-22	103.0	COG0268@1|root,COG0268@2|Bacteria,2HRKP@201174|Actinobacteria,4CTNG@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S20	-	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158462_k127_2871530_45	469383.Cwoe_2834	1.719e-56	209.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158462_k127_2871530_19	1380390.JIAT01000016_gene5648	1.067e-123	417.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4CPP2@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158462_k127_2871530_50	1380390.JIAT01000016_gene5649	9.853e-42	161.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4CQW7@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158462_k127_2871530_0	469383.Cwoe_2829	0.0	1188.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158462_k127_2871530_44	1380390.JIAT01000009_gene1986	1.542e-56	212.0	2AV6D@1|root,31KWR@2|Bacteria,2HPMX@201174|Actinobacteria,4CR03@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158462_k127_2871530_10	935866.JAER01000010_gene4041	8.125e-174	567.0	COG2355@1|root,COG2355@2|Bacteria,2HZ6F@201174|Actinobacteria,4DPCY@85009|Propionibacteriales	201174|Actinobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2871530_68	759362.KVU_0943	5.019e-06	51.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,2TU8R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	MA20_09770	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158462_k127_2871530_67	208439.AJAP_28365	8.651e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4DY2F@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158462_k127_2871530_63	1367847.JCM7686_0281	8.378e-13	77.0	COG2856@1|root,COG2856@2|Bacteria,1PCST@1224|Proteobacteria,2V5N5@28211|Alphaproteobacteria,2PZ0D@265|Paracoccus	28211|Alphaproteobacteria	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
SRR25158462_k127_2871530_48	42256.RradSPS_2355	2.385e-43	177.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
SRR25158462_k127_2871530_56	266117.Rxyl_0448	2.286e-31	144.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N,SbcCD_C
SRR25158462_k127_2871530_59	1283299.AUKG01000005_gene41	5.042e-26	116.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CQDN@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158462_k127_2871530_46	469383.Cwoe_2673	1.21e-52	192.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CQ75@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158462_k127_2871530_15	469383.Cwoe_2672	2.925e-145	480.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CPDP@84995|Rubrobacteria	84995|Rubrobacteria	E	Aldehyde dehydrogenase family	-	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158462_k127_2871530_21	469383.Cwoe_2670	1.709e-113	378.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CR1D@84995|Rubrobacteria	84995|Rubrobacteria	E	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158462_k127_2871530_34	469383.Cwoe_2260	3.331e-75	263.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria,4CQDI@84995|Rubrobacteria	84995|Rubrobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
SRR25158462_k127_2871530_13	1380390.JIAT01000002_gene6015	5.877e-147	478.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CPMW@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158462_k127_2871530_58	1380390.JIAT01000002_gene6002	2.622e-28	123.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CQPP@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158462_k127_2871530_57	469383.Cwoe_2664	1.503e-28	123.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4CQJ4@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158462_k127_2871530_3	469383.Cwoe_2663	1.402e-239	754.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CPSJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SRR25158462_k127_2871530_23	469383.Cwoe_2662	9.806e-110	371.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CPV0@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158462_k127_2871530_16	469383.Cwoe_2661	5.574e-138	462.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CPBN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
SRR25158462_k127_2871530_61	1380390.JIAT01000002_gene5997	6.239e-23	113.0	COG2891@1|root,COG2891@2|Bacteria,2HP26@201174|Actinobacteria,4CQD3@84995|Rubrobacteria	84995|Rubrobacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	MreD
SRR25158462_k127_2871530_41	469383.Cwoe_2659	1.901e-57	210.0	COG1792@1|root,COG1792@2|Bacteria	2|Bacteria	M	regulation of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158462_k127_2871530_9	1283299.AUKG01000005_gene64	6.424e-176	556.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158462_k127_2871530_52	469383.Cwoe_2657	3.619e-41	159.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4CQME@84995|Rubrobacteria	84995|Rubrobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158462_k127_2871530_42	1380390.JIAT01000002_gene5990	1.031e-56	204.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4CQFJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158462_k127_2871530_43	469383.Cwoe_2655	1.445e-56	205.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CQ2Q@84995|Rubrobacteria	84995|Rubrobacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158462_k127_2871530_26	469383.Cwoe_2653	2.757e-92	317.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria	84995|Rubrobacteria	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158462_k127_2871530_1	469383.Cwoe_2652	0.0	1065.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CPR8@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158462_k127_2871530_4	469383.Cwoe_2649	3.42e-232	727.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CPB5@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158462_k127_2871530_35	469383.Cwoe_2648	2.773e-74	250.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158462_k127_2980849_54	1283299.AUKG01000001_gene2765	2.272e-83	280.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4CPTH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158462_k127_2980849_6	469383.Cwoe_1593	7.849e-242	759.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158462_k127_2980849_40	1283299.AUKG01000001_gene2782	2.698e-128	417.0	COG3246@1|root,COG3246@2|Bacteria,2I9EQ@201174|Actinobacteria,4CSHR@84995|Rubrobacteria	84995|Rubrobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158462_k127_2980849_22	1283299.AUKG01000001_gene2783	1.016e-173	554.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4CU2K@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158462_k127_2980849_62	469383.Cwoe_1596	1.41e-77	273.0	COG0789@1|root,COG0789@2|Bacteria,2HPW7@201174|Actinobacteria,4CRAT@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158462_k127_2980849_10	469383.Cwoe_0601	1.876e-202	666.0	COG2114@1|root,COG2909@1|root,COG3899@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc
SRR25158462_k127_2980849_63	99598.Cal7507_3216	2.815e-77	267.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria,1HP1Q@1161|Nostocales	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_2980849_44	469383.Cwoe_1600	3.177e-108	357.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4CPAW@84995|Rubrobacteria	84995|Rubrobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158462_k127_2980849_61	1380390.JIAT01000011_gene2726	1.162e-77	274.0	COG1309@1|root,COG1309@2|Bacteria,2IEV2@201174|Actinobacteria,4CPWP@84995|Rubrobacteria	84995|Rubrobacteria	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
SRR25158462_k127_2980849_117	1283299.AUKG01000001_gene2792	1.184e-11	66.0	2A5U7@1|root,31PFR@2|Bacteria,2HRV2@201174|Actinobacteria,4CTYF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_124	446466.Cfla_2903	4.817e-07	59.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria,4F1GY@85016|Cellulomonadaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158462_k127_2980849_120	1283299.AUKG01000001_gene2795	1.85e-10	70.0	2AUM4@1|root,31K9W@2|Bacteria,2HP6Z@201174|Actinobacteria,4CQJ3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158462_k127_2980849_51	469383.Cwoe_1607	1.624e-97	326.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CPTV@84995|Rubrobacteria	84995|Rubrobacteria	S	TIGRFAM degV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158462_k127_2980849_113	1521187.JPIM01000170_gene1015	1.854e-13	73.0	COG2333@1|root,COG2333@2|Bacteria,2GBHC@200795|Chloroflexi,374W4@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Excalibur,Lactamase_B
SRR25158462_k127_2980849_91	469383.Cwoe_1612	3.538e-35	138.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CQFF@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158462_k127_2980849_99	1123354.AUDR01000016_gene1293	2.226e-24	109.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,1KRT2@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
SRR25158462_k127_2980849_118	82654.Pse7367_1684	1.2e-11	76.0	COG5007@1|root,COG5007@2|Bacteria,1GRBE@1117|Cyanobacteria,1HIB9@1150|Oscillatoriales	1117|Cyanobacteria	K	BolA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	BolA
SRR25158462_k127_2980849_18	469383.Cwoe_4411	2.221e-177	567.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CSBR@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158462_k127_2980849_60	1380390.JIAT01000011_gene2743	7.572e-78	269.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4CQB7@84995|Rubrobacteria	84995|Rubrobacteria	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158462_k127_2980849_75	469383.Cwoe_5454	6.212e-57	221.0	COG3119@1|root,COG3119@2|Bacteria,2HRVJ@201174|Actinobacteria,4CTZ0@84995|Rubrobacteria	84995|Rubrobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_7	469383.Cwoe_1613	1.016e-241	769.0	COG0392@1|root,COG0438@1|root,COG0392@2|Bacteria,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CPA3@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,LPG_synthase_TM
SRR25158462_k127_2980849_119	1306990.BARG01000068_gene7564	1.496e-10	72.0	COG1246@1|root,COG1246@2|Bacteria,2I3ZH@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158462_k127_2980849_0	469383.Cwoe_1617	0.0	1835.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CPS6@84995|Rubrobacteria	84995|Rubrobacteria	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158462_k127_2980849_23	37919.EP51_26205	3.379e-173	557.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4FUME@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158462_k127_2980849_50	469383.Cwoe_1540	2.141e-100	341.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,4CR0Z@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158462_k127_2980849_37	929712.KI912613_gene4841	1.393e-133	430.0	COG0767@1|root,COG0767@2|Bacteria,2IAUN@201174|Actinobacteria,4CR2S@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158462_k127_2980849_36	1380390.JIAT01000011_gene2768	4.358e-136	436.0	COG0767@1|root,COG0767@2|Bacteria,2GJ27@201174|Actinobacteria,4CPTC@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158462_k127_2980849_38	469383.Cwoe_1621	9.485e-130	422.0	COG1127@1|root,COG1127@2|Bacteria,2GJ1T@201174|Actinobacteria,4CPHI@84995|Rubrobacteria	84995|Rubrobacteria	Q	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158462_k127_2980849_21	1380390.JIAT01000011_gene2776	5.214e-174	574.0	COG1033@1|root,COG1033@2|Bacteria,2I731@201174|Actinobacteria,4CR6J@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
SRR25158462_k127_2980849_110	929712.KI912613_gene4832	2.463e-15	88.0	COG1225@1|root,COG1225@2|Bacteria,2HT4T@201174|Actinobacteria,4CSH8@84995|Rubrobacteria	84995|Rubrobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158462_k127_2980849_80	469383.Cwoe_1630	1.428e-50	188.0	COG3382@1|root,COG3382@2|Bacteria,2HAYZ@201174|Actinobacteria,4CT9S@84995|Rubrobacteria	84995|Rubrobacteria	S	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_93	1380390.JIAT01000011_gene2779	1.175e-31	136.0	2FIW0@1|root,34AM7@2|Bacteria,2HPD8@201174|Actinobacteria,4CQR1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_114	1380390.JIAT01000011_gene2780	3.555e-13	75.0	2BH9C@1|root,32BAU@2|Bacteria,2HP96@201174|Actinobacteria,4CQMF@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_17	1380390.JIAT01000011_gene2783	3.079e-178	587.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4CP6E@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class I and II	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158462_k127_2980849_33	469383.Cwoe_1636	4.086e-143	463.0	COG0454@1|root,COG0456@2|Bacteria,2GNAV@201174|Actinobacteria,4CQ54@84995|Rubrobacteria	84995|Rubrobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_77	1380390.JIAT01000011_gene2787	3.463e-55	207.0	COG0122@1|root,COG0122@2|Bacteria,2HPWW@201174|Actinobacteria,4CRBJ@84995|Rubrobacteria	84995|Rubrobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158462_k127_2980849_39	1229172.JQFA01000004_gene1725	2.439e-128	438.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1HF9H@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,EAL,GAF,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158462_k127_2980849_58	929712.KI912613_gene4827	7.429e-81	281.0	COG0715@1|root,COG0715@2|Bacteria,2HFU1@201174|Actinobacteria,4CQ47@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
SRR25158462_k127_2980849_73	469383.Cwoe_1643	3.784e-61	230.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CQ5D@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158462_k127_2980849_59	326424.FRAAL1558	5.277e-79	272.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EU1S@85013|Frankiales	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
SRR25158462_k127_2980849_57	469383.Cwoe_5534	3.8e-81	285.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4CRVC@84995|Rubrobacteria	84995|Rubrobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158462_k127_2980849_74	1380390.JIAT01000009_gene1158	4.693e-57	202.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158462_k127_2980849_126	246196.MSMEI_6353	1.006e-05	55.0	COG1309@1|root,COG1309@2|Bacteria,2I2NW@201174|Actinobacteria,236B7@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_2980849_28	1449346.JQMO01000002_gene695	2.733e-162	521.0	COG1262@1|root,COG1262@2|Bacteria,2IC9K@201174|Actinobacteria,2M4A8@2063|Kitasatospora	201174|Actinobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_100	395493.BegalDRAFT_0070	1.673e-23	115.0	COG1361@1|root,COG2706@1|root,COG4409@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria,COG4409@2|Bacteria,1NB7P@1224|Proteobacteria,1SCSF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
SRR25158462_k127_2980849_8	469383.Cwoe_5128	6.073e-214	684.0	COG3119@1|root,COG3119@2|Bacteria,2IA3D@201174|Actinobacteria	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158462_k127_2980849_76	266117.Rxyl_2350	8.971e-56	206.0	COG4424@1|root,COG4424@2|Bacteria,2GNGY@201174|Actinobacteria	201174|Actinobacteria	S	carbohydrate metabolic process	stf0	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
SRR25158462_k127_2980849_16	266117.Rxyl_2349	2.888e-182	579.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	atsG	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158462_k127_2980849_125	426716.JOAJ01000009_gene5850	9.465e-07	58.0	COG0406@1|root,COG0406@2|Bacteria,2GM22@201174|Actinobacteria,4FVGX@85025|Nocardiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158462_k127_2980849_14	469383.Cwoe_1645	2.509e-185	589.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CPGF@84995|Rubrobacteria	84995|Rubrobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158462_k127_2980849_35	1380390.JIAT01000011_gene2800	2.264e-136	444.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CPXK@84995|Rubrobacteria	84995|Rubrobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158462_k127_2980849_47	1380390.JIAT01000009_gene1974	2.416e-105	347.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4CPQD@84995|Rubrobacteria	84995|Rubrobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158462_k127_2980849_102	469383.Cwoe_1654	1.583e-18	99.0	2A05G@1|root,30N88@2|Bacteria,2HP1P@201174|Actinobacteria,4CQC6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_30	1380390.JIAT01000011_gene2810	1.24e-151	487.0	COG0387@1|root,COG0387@2|Bacteria,2IA57@201174|Actinobacteria,4CSE2@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158462_k127_2980849_69	1449126.JQKL01000013_gene3422	3.353e-73	258.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex,PGPGW
SRR25158462_k127_2980849_72	469383.Cwoe_1113	2.647e-61	214.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4CQMC@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158462_k127_2980849_112	1283299.AUKG01000001_gene2896	3.637e-14	79.0	2BG9U@1|root,32A77@2|Bacteria,2HPFU@201174|Actinobacteria,4CQUB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_11	1283299.AUKG01000001_gene2897	6.428e-197	621.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CRMB@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_2980849_115	929712.KI912613_gene874	5.215e-13	74.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_96	469383.Cwoe_1506	4.531e-29	126.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_2980849_5	1380390.JIAT01000009_gene522	5.599e-269	841.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CP9R@84995|Rubrobacteria	84995|Rubrobacteria	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158462_k127_2980849_97	469383.Cwoe_3948	7.666e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4CQPR@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158462_k127_2980849_34	1122939.ATUD01000001_gene295	7.394e-140	474.0	COG1404@1|root,COG1404@2|Bacteria,2IA44@201174|Actinobacteria	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,P_proprotein,Peptidase_S8
SRR25158462_k127_2980849_82	1283299.AUKG01000002_gene5342	2.404e-49	184.0	COG0398@1|root,COG0398@2|Bacteria,2HP5Q@201174|Actinobacteria,4CQHS@84995|Rubrobacteria	84995|Rubrobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158462_k127_2980849_26	469383.Cwoe_5408	3.388e-165	543.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CP74@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix containing domain	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158462_k127_2980849_104	469383.Cwoe_2923	1.248e-17	83.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_122	1408422.JHYF01000011_gene3429	9.01e-08	63.0	COG1664@1|root,COG1664@2|Bacteria,1V1NS@1239|Firmicutes,24TEV@186801|Clostridia,36ME3@31979|Clostridiaceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_121	309800.C498_03305	1.863e-08	64.0	arCOG03006@1|root,arCOG03006@2157|Archaea,2XYR1@28890|Euryarchaeota,23WX6@183963|Halobacteria	183963|Halobacteria	S	COG0662 Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_2980849_87	1121920.AUAU01000004_gene861	2.937e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,3Y5K3@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_2980849_71	1144275.COCOR_04930	2.669e-64	235.0	COG4430@1|root,COG4430@2|Bacteria,1NEN6@1224|Proteobacteria,434J2@68525|delta/epsilon subdivisions,2WYWB@28221|Deltaproteobacteria,2Z0SI@29|Myxococcales	28221|Deltaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158462_k127_2980849_31	1380390.JIAT01000010_gene4168	2.507e-150	481.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CQ1M@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158462_k127_2980849_116	1229780.BN381_210013	7.49e-13	76.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SRR25158462_k127_2980849_13	469383.Cwoe_0846	1.232e-186	595.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4CR3U@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158462_k127_2980849_2	1380390.JIAT01000011_gene2762	0.0	1055.0	COG3968@1|root,COG3968@2|Bacteria,2GMA9@201174|Actinobacteria,4CS2J@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutamine synthetase type III N terminal	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158462_k127_2980849_101	1283299.AUKG01000003_gene588	2.483e-20	106.0	COG0454@1|root,COG0456@2|Bacteria,2HPUK@201174|Actinobacteria,4CR8I@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158462_k127_2980849_90	1380390.JIAT01000009_gene422	2.619e-38	149.0	COG0791@1|root,COG0791@2|Bacteria,2HQZH@201174|Actinobacteria,4CSSW@84995|Rubrobacteria	84995|Rubrobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_66	1380390.JIAT01000013_gene61	2.237e-74	255.0	COG1309@1|root,COG1309@2|Bacteria,2GNIP@201174|Actinobacteria,4CSFA@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_2980849_106	1179773.BN6_85050	1.919e-17	96.0	COG5373@1|root,COG5373@2|Bacteria,2GJII@201174|Actinobacteria,4DYXP@85010|Pseudonocardiales	201174|Actinobacteria	D	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158462_k127_2980849_4	1283299.AUKG01000001_gene2904	4.225e-281	888.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,4CPBM@84995|Rubrobacteria	84995|Rubrobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158462_k127_2980849_56	1380390.JIAT01000011_gene2820	1.923e-81	287.0	COG0846@1|root,COG0846@2|Bacteria,2IFPA@201174|Actinobacteria,4CQ9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158462_k127_2980849_83	1380390.JIAT01000009_gene1187	6.352e-49	189.0	COG0637@1|root,COG0637@2|Bacteria,2I7TC@201174|Actinobacteria,4CQ6H@84995|Rubrobacteria	84995|Rubrobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158462_k127_2980849_94	1283299.AUKG01000001_gene2913	3.853e-30	133.0	2AUJS@1|root,31K8C@2|Bacteria,2HP69@201174|Actinobacteria,4CQI1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_19	1283299.AUKG01000001_gene2914	4.677e-176	579.0	COG0739@1|root,COG0741@1|root,COG0739@2|Bacteria,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4CPBG@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
SRR25158462_k127_2980849_105	1380390.JIAT01000011_gene2830	1.626e-17	95.0	2904D@1|root,2ZMUB@2|Bacteria,2H0MU@201174|Actinobacteria,4CSUN@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_92	469383.Cwoe_1668	1.726e-32	135.0	COG2820@1|root,COG2820@2|Bacteria,2I4KP@201174|Actinobacteria,4CQU2@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158462_k127_2980849_15	1380390.JIAT01000011_gene2763	5.842e-183	589.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CP60@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158462_k127_2980849_85	469383.Cwoe_1640	5.4e-47	171.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4CQ3C@84995|Rubrobacteria	84995|Rubrobacteria	E	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158462_k127_2980849_41	469383.Cwoe_1670	3.852e-127	417.0	COG0789@1|root,COG2114@1|root,COG0789@2|Bacteria,COG2114@2|Bacteria,2ICT6@201174|Actinobacteria,4CR4V@84995|Rubrobacteria	84995|Rubrobacteria	KT	Adenylate cyclase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	Ad_Cy_reg,Guanylate_cyc,MerR_1
SRR25158462_k127_2980849_45	469383.Cwoe_1671	1.312e-106	371.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CQ9P@84995|Rubrobacteria	84995|Rubrobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
SRR25158462_k127_2980849_68	1283299.AUKG01000001_gene2922	1.821e-73	265.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158462_k127_2980849_3	1283299.AUKG01000001_gene2923	1.073e-316	979.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CPFJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158462_k127_2980849_52	469383.Cwoe_1674	2.063e-93	313.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CPWZ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158462_k127_2980849_89	1380390.JIAT01000011_gene2843	1.565e-39	154.0	COG1539@1|root,COG1539@2|Bacteria,2HQ0Z@201174|Actinobacteria,4CRGX@84995|Rubrobacteria	84995|Rubrobacteria	H	Dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158462_k127_2980849_79	469383.Cwoe_1676	7.446e-54	196.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4CQM0@84995|Rubrobacteria	84995|Rubrobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158462_k127_2980849_84	469383.Cwoe_4682	9.056e-48	180.0	COG0625@1|root,COG0625@2|Bacteria	2|Bacteria	O	glutathione transferase activity	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
SRR25158462_k127_2980849_53	469383.Cwoe_1678	9.242e-89	300.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CQ5C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158462_k127_2980849_42	1380390.JIAT01000011_gene2854	2.231e-125	409.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CPE8@84995|Rubrobacteria	84995|Rubrobacteria	J	Dihydrouridine synthase (Dus)	-	-	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158462_k127_2980849_78	1283299.AUKG01000001_gene2943	1.084e-54	198.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CQG1@84995|Rubrobacteria	84995|Rubrobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158462_k127_2980849_12	1122939.ATUD01000002_gene1184	1.956e-188	600.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CR5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158462_k127_2980849_1	326424.FRAAL6680	0.0	1088.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4ERE5@85013|Frankiales	201174|Actinobacteria	O	Clp domain protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158462_k127_2980849_27	1449355.JQNR01000005_gene3890	1.032e-162	573.0	COG0741@1|root,COG3209@1|root,COG0741@2|Bacteria,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SRR25158462_k127_2980849_20	469383.Cwoe_1556	1.426e-174	554.0	COG0667@1|root,COG0667@2|Bacteria,2HQ4U@201174|Actinobacteria,4CRMQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158462_k127_2980849_48	1380390.JIAT01000010_gene3597	4.765e-104	354.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRH0@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_2980849_24	1380390.JIAT01000011_gene2865	4.801e-171	567.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4CPEN@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA integrity scanning protein DisA	-	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH_2
SRR25158462_k127_2980849_67	1380390.JIAT01000011_gene2866	1.004e-73	259.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CPVJ@84995|Rubrobacteria	84995|Rubrobacteria	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158462_k127_2980849_86	469383.Cwoe_1688	1.968e-42	169.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CQE7@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158462_k127_2980849_127	1283299.AUKG01000002_gene4357	4.342e-05	47.0	2AXJJ@1|root,31PJM@2|Bacteria,2HRXU@201174|Actinobacteria,4CU14@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_43	1122939.ATUD01000002_gene1191	4.837e-109	364.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CQ7N@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR25158462_k127_2980849_88	292459.STH3122	3.232e-41	168.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158462_k127_2980849_9	1283299.AUKG01000002_gene4730	9.506e-207	659.0	COG0318@1|root,COG0318@2|Bacteria,2GKDF@201174|Actinobacteria,4CPC4@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158462_k127_2980849_29	469383.Cwoe_1691	3.947e-157	508.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CP99@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158462_k127_2980849_70	1380390.JIAT01000014_gene6271	2.819e-65	229.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CPWF@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158462_k127_2980849_49	1380390.JIAT01000014_gene6270	1.507e-102	338.0	COG1595@1|root,COG1595@2|Bacteria,2HQ0U@201174|Actinobacteria,4CRGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_2980849_32	675635.Psed_2775	1.776e-147	473.0	COG0454@1|root,COG0456@2|Bacteria,2H994@201174|Actinobacteria	201174|Actinobacteria	H	sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_111	1206737.BAGF01000056_gene3461	6.476e-15	87.0	COG3468@1|root,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria,4FW2W@85025|Nocardiaceae	201174|Actinobacteria	MU	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
SRR25158462_k127_2980849_109	1283287.KB822581_gene1468	9.939e-17	84.0	2C530@1|root,2ZRHX@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158462_k127_2980849_55	1380390.JIAT01000011_gene2334	1.83e-81	288.0	28MY8@1|root,32YD0@2|Bacteria,2HR9A@201174|Actinobacteria,4CT5U@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_46	469383.Cwoe_4746	1.399e-106	353.0	COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158462_k127_2980849_81	1380390.JIAT01000015_gene5805	8.676e-50	198.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CSII@84995|Rubrobacteria	84995|Rubrobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158462_k127_2980849_25	1283299.AUKG01000001_gene3035	4.131e-166	539.0	COG0204@1|root,COG0240@1|root,COG0204@2|Bacteria,COG0240@2|Bacteria,2GJ6V@201174|Actinobacteria,4CP70@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158462_k127_2980849_64	469383.Cwoe_1762	8.52e-77	261.0	COG1595@1|root,COG1595@2|Bacteria,2HG39@201174|Actinobacteria,4CP8K@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_2980849_107	1122939.ATUD01000002_gene1204	3.861e-17	85.0	2AWQX@1|root,31NMV@2|Bacteria,2HR6S@201174|Actinobacteria,4CT2Q@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2980849_123	1151118.KB895784_gene3305	4.286e-07	57.0	2C9IE@1|root,32UBS@2|Bacteria,2INT4@201174|Actinobacteria,1WBCV@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158462_k127_2980849_65	469383.Cwoe_1764	1.906e-75	262.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CQ6Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRR25158462_k127_2993191_85	469383.Cwoe_5571	7.206e-44	160.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4CPIU@84995|Rubrobacteria	84995|Rubrobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158462_k127_2993191_117	590998.Celf_0635	1.701e-16	93.0	COG3387@1|root,COG3387@2|Bacteria,2ICV9@201174|Actinobacteria,4F0TM@85016|Cellulomonadaceae	201174|Actinobacteria	G	PFAM glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_141	1499968.TCA2_5335	0.0002294	44.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HRQH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_137	1828.JOKB01000054_gene1115	1.055e-05	57.0	COG3693@1|root,COG3693@2|Bacteria,2GN8V@201174|Actinobacteria,4FZTD@85025|Nocardiaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_cc
SRR25158462_k127_2993191_36	928724.SacglDRAFT_00313	9.319e-94	313.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4DYP8@85010|Pseudonocardiales	201174|Actinobacteria	S	Short-chain alcohol dehydrogenase	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
SRR25158462_k127_2993191_113	1449976.KALB_7530	5.171e-18	89.0	2DNZR@1|root,32ZYK@2|Bacteria,2GQYS@201174|Actinobacteria,4E5QZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
SRR25158462_k127_2993191_69	1380390.JIAT01000011_gene2559	9.893e-60	218.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4CSEV@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158462_k127_2993191_128	1123269.NX02_14300	7.879e-09	68.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K2CT@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158462_k127_2993191_121	1298880.AUEV01000004_gene1890	6.083e-13	82.0	COG2931@1|root,COG2931@2|Bacteria,2I644@201174|Actinobacteria	201174|Actinobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_16	1038859.AXAU01000002_gene283	1.983e-145	473.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Guanylate_cyc,Hydrolase_4,Trans_reg_C
SRR25158462_k127_2993191_130	1146883.BLASA_1767	1.873e-08	64.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria,4EX0H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_106	469383.Cwoe_3152	1.902e-28	130.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria,4CQ9R@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_2993191_109	469383.Cwoe_3167	2.328e-22	111.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_2993191_74	861299.J421_0439	4.795e-53	207.0	COG1470@1|root,COG1572@1|root,COG3227@1|root,COG4447@1|root,COG1470@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG4447@2|Bacteria,1ZT2Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_134	927677.ALVU02000001_gene3372	3.262e-06	62.0	COG3391@1|root,COG3391@2|Bacteria,1G499@1117|Cyanobacteria	1117|Cyanobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,VPEP
SRR25158462_k127_2993191_122	314230.DSM3645_28792	2.676e-12	82.0	COG1357@1|root,COG1357@2|Bacteria,2J2VS@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_89	1283299.AUKG01000001_gene1591	2.719e-39	171.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158462_k127_2993191_21	1283299.AUKG01000001_gene1590	3.711e-141	485.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_114	469383.Cwoe_1170	3.785e-17	96.0	2B09U@1|root,31SKS@2|Bacteria,2HUBE@201174|Actinobacteria,4CU0W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_100	110319.CF8_0357	1.825e-30	135.0	COG3835@1|root,COG3835@2|Bacteria,2IGZP@201174|Actinobacteria	201174|Actinobacteria	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158462_k127_2993191_28	1283299.AUKG01000001_gene1590	2.332e-129	445.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_17	469383.Cwoe_1710	1.955e-144	495.0	COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,2HGJ9@201174|Actinobacteria,4CRYN@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_2993191_105	469383.Cwoe_4469	1.382e-29	130.0	2C5HJ@1|root,2Z812@2|Bacteria	2|Bacteria	S	Tetraprenyl-beta-curcumene synthase	ytpB	-	4.2.3.130	ko:K16188	-	-	R10009	RC02994	ko00000,ko01000	-	-	-	DUF2600
SRR25158462_k127_2993191_32	1283299.AUKG01000001_gene2044	3.254e-109	363.0	COG3481@1|root,COG3481@2|Bacteria,2IRFS@201174|Actinobacteria,4CPMU@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD
SRR25158462_k127_2993191_2	469383.Cwoe_5785	1.637e-263	828.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4CPJ7@84995|Rubrobacteria	84995|Rubrobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158462_k127_2993191_68	1380390.JIAT01000011_gene2653	3.687e-61	222.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4CQ8G@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_2993191_93	1122138.AQUZ01000055_gene6261	1.48e-35	143.0	COG1708@1|root,COG1708@2|Bacteria,2GUWM@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158462_k127_2993191_125	1032480.MLP_03950	2.645e-10	68.0	COG2250@1|root,COG2250@2|Bacteria,2GYNE@201174|Actinobacteria	201174|Actinobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_8	383372.Rcas_1653	3.784e-166	550.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi,376RD@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158462_k127_2993191_80	1283299.AUKG01000004_gene1145	1.428e-46	181.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CRKI@84995|Rubrobacteria	84995|Rubrobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158462_k127_2993191_47	1116232.AHBF01000072_gene9136	6.378e-78	266.0	COG0693@1|root,COG0693@2|Bacteria,2H6FV@201174|Actinobacteria	201174|Actinobacteria	S	ThiJ PfpI	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158462_k127_2993191_75	1122939.ATUD01000011_gene2224	2.566e-49	181.0	COG3871@1|root,COG3871@2|Bacteria,2I2QZ@201174|Actinobacteria,4CQ6F@84995|Rubrobacteria	84995|Rubrobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158462_k127_2993191_103	1283299.AUKG01000004_gene1145	3.177e-30	137.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CRKI@84995|Rubrobacteria	84995|Rubrobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158462_k127_2993191_55	1068980.ARVW01000001_gene1546	7.977e-73	263.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
SRR25158462_k127_2993191_88	469371.Tbis_0875	2.951e-40	168.0	COG0367@1|root,COG0367@2|Bacteria,2I9PY@201174|Actinobacteria	201174|Actinobacteria	E	asparagine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase
SRR25158462_k127_2993191_46	1380390.JIAT01000011_gene2681	1.123e-81	289.0	COG2133@1|root,COG2133@2|Bacteria,2H9JT@201174|Actinobacteria,4CQXG@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158462_k127_2993191_120	861299.J421_6059	4.153e-13	82.0	COG2091@1|root,COG2091@2|Bacteria,1ZV9N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	-
SRR25158462_k127_2993191_23	929712.KI912613_gene2534	3.801e-136	441.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158462_k127_2993191_110	1463879.JOHP01000012_gene1035	3.365e-20	102.0	29YC4@1|root,30K6H@2|Bacteria,2H0Z2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_115	1209984.BN978_06267	1.124e-16	89.0	2CQU4@1|root,32SMT@2|Bacteria,2HZJV@201174|Actinobacteria,23EDS@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_9	1122939.ATUD01000016_gene1814	8.708e-161	514.0	COG0451@1|root,COG0451@2|Bacteria,2GPN0@201174|Actinobacteria	201174|Actinobacteria	M	Nad-dependent epimerase dehydratase	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158462_k127_2993191_39	449447.MAE_46400	1.55e-91	307.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1G41K@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158462_k127_2993191_52	1380347.JNII01000007_gene407	1.627e-73	267.0	COG0438@1|root,COG0438@2|Bacteria,2I6NY@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_2993191_13	1173021.ALWA01000035_gene3870	6.679e-149	496.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1G2HS@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158462_k127_2993191_63	357808.RoseRS_2675	5.432e-65	246.0	COG2227@1|root,COG2227@2|Bacteria,2GAP4@200795|Chloroflexi,376X2@32061|Chloroflexia	32061|Chloroflexia	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SRR25158462_k127_2993191_51	1122939.ATUD01000006_gene1703	9.396e-74	261.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CPVF@84995|Rubrobacteria	84995|Rubrobacteria	GM	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158462_k127_2993191_33	1122939.ATUD01000006_gene1702	5.697e-104	352.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4CRRB@84995|Rubrobacteria	84995|Rubrobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,Wzt_C
SRR25158462_k127_2993191_19	931627.MycrhDRAFT_5099	1.604e-141	471.0	2EE4T@1|root,337ZF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_48	1283299.AUKG01000001_gene2292	2.958e-77	290.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_2993191_95	35754.JNYJ01000002_gene6958	1.207e-33	151.0	2E35F@1|root,32Y5E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_94	1121946.AUAX01000003_gene1394	2.645e-34	149.0	2E3PP@1|root,32YMR@2|Bacteria,2GSCU@201174|Actinobacteria,4DFEC@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_14	1283299.AUKG01000001_gene2039	9.761e-148	479.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CPTQ@84995|Rubrobacteria	84995|Rubrobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158462_k127_2993191_56	469383.Cwoe_5897	5.153e-72	278.0	COG5542@1|root,COG5542@2|Bacteria,2HNS4@201174|Actinobacteria,4CPZM@84995|Rubrobacteria	84995|Rubrobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158462_k127_2993191_143	99598.Cal7507_4879	0.0002794	47.0	COG4691@1|root,COG4691@2|Bacteria,1GA88@1117|Cyanobacteria,1HPB7@1161|Nostocales	1117|Cyanobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	RHH_5
SRR25158462_k127_2993191_124	1430440.MGMSRv2_3883	8.864e-11	68.0	COG4113@1|root,COG4113@2|Bacteria,1N7ET@1224|Proteobacteria,2UG7M@28211|Alphaproteobacteria,2JY5V@204441|Rhodospirillales	204441|Rhodospirillales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158462_k127_2993191_58	1380390.JIAT01000009_gene2056	2.957e-67	239.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4CPVG@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158462_k127_2993191_20	469383.Cwoe_5789	3.557e-141	469.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CPRY@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158462_k127_2993191_59	469383.Cwoe_3157	8.026e-67	239.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria,4CQ10@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158462_k127_2993191_82	452637.Oter_3452	3.446e-45	186.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_23,Methyltransf_25
SRR25158462_k127_2993191_73	1303518.CCALI_01268	2.048e-54	206.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_2993191_107	1219049.SP5_039_00010	2.248e-28	124.0	COG1216@1|root,COG1216@2|Bacteria,1RDAK@1224|Proteobacteria,2UBKE@28211|Alphaproteobacteria,2K0ZU@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_2993191_118	1121861.KB899929_gene261	2.169e-16	93.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2U4R4@28211|Alphaproteobacteria,2JVD9@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158462_k127_2993191_50	345341.KUTG_05088	4.483e-74	261.0	COG1215@1|root,COG2227@1|root,COG4942@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria,COG4942@2|Bacteria,2I4KI@201174|Actinobacteria,4DYH9@85010|Pseudonocardiales	201174|Actinobacteria	DHM	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
SRR25158462_k127_2993191_64	309801.trd_A0816	1.304e-64	241.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158462_k127_2993191_77	469383.Cwoe_5297	1.391e-47	194.0	COG3307@1|root,COG3307@2|Bacteria,2HREZ@201174|Actinobacteria,4CTDF@84995|Rubrobacteria	84995|Rubrobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158462_k127_2993191_97	1380390.JIAT01000016_gene5568	2.937e-32	141.0	COG2723@1|root,COG2723@2|Bacteria,2IAWK@201174|Actinobacteria,4CRKI@84995|Rubrobacteria	84995|Rubrobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
SRR25158462_k127_2993191_0	1313172.YM304_09490	0.0	1389.0	COG1201@1|root,COG1201@2|Bacteria,2I6VR@201174|Actinobacteria,4CNBF@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DEAD-like helicases superfamily	-	-	-	ko:K03724,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR25158462_k127_2993191_66	1380390.JIAT01000009_gene2041	1.37e-63	246.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CPNY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158462_k127_2993191_99	1122611.KB903941_gene2150	1.235e-31	140.0	2EDD5@1|root,3379H@2|Bacteria,2ISXN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_72	1123023.JIAI01000016_gene3391	7.1e-55	209.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Protein-L-isoaspartate(D-aspartate) O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158462_k127_2993191_144	118173.KB235914_gene2249	0.0004433	53.0	COG2931@1|root,COG5563@1|root,COG2931@2|Bacteria,COG5563@2|Bacteria,1G9WZ@1117|Cyanobacteria,1HH6W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158462_k127_2993191_104	472175.EL18_02677	3.379e-30	138.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,43JGB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	3.4.24.40	ko:K01406,ko:K07004	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	An_peroxidase,Cadherin,Calx-beta,Exo_endo_phos,HemolysinCabind,Metallophos,PPC,Peptidase_M10_C
SRR25158462_k127_2993191_83	1283299.AUKG01000001_gene2013	4.742e-45	168.0	COG2411@1|root,COG2411@2|Bacteria,2HNQQ@201174|Actinobacteria,4CPX9@84995|Rubrobacteria	84995|Rubrobacteria	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158462_k127_2993191_70	748280.NH8B_2023	1.455e-57	203.0	COG3832@1|root,COG3832@2|Bacteria,1RICZ@1224|Proteobacteria,2VTB3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158462_k127_2993191_78	469383.Cwoe_5811	2.277e-47	172.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CQN4@84995|Rubrobacteria	84995|Rubrobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158462_k127_2993191_4	1120950.KB892775_gene1166	6.039e-215	681.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4DNNQ@85009|Propionibacteriales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158462_k127_2993191_145	390989.JOEG01000005_gene1973	0.0009658	51.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,4D8V7@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_2993191_40	1283299.AUKG01000001_gene1992	3.336e-90	306.0	COG0702@1|root,COG0702@2|Bacteria,2HM0H@201174|Actinobacteria,4CQ71@84995|Rubrobacteria	84995|Rubrobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158462_k127_2993191_76	469383.Cwoe_5818	9.399e-49	175.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4CQEK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158462_k127_2993191_87	1380390.JIAT01000009_gene513	9.208e-41	157.0	COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,2HQCW@201174|Actinobacteria,4CRXA@84995|Rubrobacteria	84995|Rubrobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158462_k127_2993191_12	1380390.JIAT01000009_gene2017	6.263e-155	503.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4CPSM@84995|Rubrobacteria	84995|Rubrobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158462_k127_2993191_61	469383.Cwoe_1100	4.538e-66	255.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CQGA@84995|Rubrobacteria	84995|Rubrobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158462_k127_2993191_62	1132509.C447_14266	1.641e-65	231.0	arCOG11916@1|root,arCOG11916@2157|Archaea,2XVSD@28890|Euryarchaeota,23SJ1@183963|Halobacteria	183963|Halobacteria	S	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158462_k127_2993191_44	1380390.JIAT01000010_gene4131	5.147e-84	292.0	COG0477@1|root,COG2814@2|Bacteria,2HQMP@201174|Actinobacteria,4CS79@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_2993191_22	1122939.ATUD01000005_gene2570	1.932e-136	447.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4CRUH@84995|Rubrobacteria	84995|Rubrobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.8	ko:K00103	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158462_k127_2993191_24	479433.Caci_5489	1.188e-134	439.0	COG3616@1|root,COG3616@2|Bacteria,2GJMB@201174|Actinobacteria	201174|Actinobacteria	E	Alanine racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
SRR25158462_k127_2993191_102	861299.J421_5655	3.029e-30	128.0	COG2197@1|root,COG2197@2|Bacteria,1ZV33@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158462_k127_2993191_27	1370121.AUWS01000030_gene2904	1.703e-130	448.0	29UDG@1|root,30FQ4@2|Bacteria,2IG2H@201174|Actinobacteria,23DI4@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_11	591159.ACEZ01000207_gene6998	5.487e-155	499.0	2DBR9@1|root,2ZAJD@2|Bacteria,2I83R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_45	323261.Noc_2190	6.443e-83	294.0	2C2AK@1|root,30RHD@2|Bacteria,1NSEW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_29	469383.Cwoe_1054	3.395e-127	425.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CPJ2@84995|Rubrobacteria	84995|Rubrobacteria	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158462_k127_2993191_38	1206731.BAGB01000061_gene3416	1.95e-92	310.0	COG1024@1|root,COG1024@2|Bacteria,2I9BK@201174|Actinobacteria,4FTVH@85025|Nocardiaceae	201174|Actinobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158462_k127_2993191_98	685035.ADAE01000002_gene2523	7.278e-32	130.0	COG2050@1|root,COG2050@2|Bacteria,1N4SW@1224|Proteobacteria,2UD9E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
SRR25158462_k127_2993191_123	76114.ebD37	6.074e-12	68.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
SRR25158462_k127_2993191_84	1283299.AUKG01000001_gene2849	2.095e-44	169.0	28W7P@1|root,2ZI89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_57	1283299.AUKG01000001_gene2848	2.452e-70	248.0	COG4849@1|root,COG4849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SRR25158462_k127_2993191_49	1188256.BASI01000002_gene3295	1.011e-76	269.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616,Exo_endo_phos
SRR25158462_k127_2993191_133	1068980.ARVW01000001_gene29	1.431e-06	57.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4EBAV@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_2993191_132	330084.JNYZ01000004_gene708	2.578e-07	60.0	COG0640@1|root,COG0640@2|Bacteria,2GQ1F@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_2993191_136	1068980.ARVW01000001_gene29	7.319e-06	55.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,4EBAV@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_2993191_135	1123322.KB904712_gene5391	4.562e-06	58.0	COG0640@1|root,COG0640@2|Bacteria,2IS0F@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_2993191_111	1206737.BAGF01000149_gene6024	8.238e-20	103.0	COG2508@1|root,COG2508@2|Bacteria,2GP6C@201174|Actinobacteria,4FVFC@85025|Nocardiaceae	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158462_k127_2993191_142	314230.DSM3645_28792	0.0002609	55.0	COG1357@1|root,COG1357@2|Bacteria,2J2VS@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_90	1283299.AUKG01000001_gene2701	3.777e-37	164.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	MRJP
SRR25158462_k127_2993191_15	1283299.AUKG01000001_gene1590	1.077e-147	506.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_108	469383.Cwoe_1170	2.314e-23	114.0	2B09U@1|root,31SKS@2|Bacteria,2HUBE@201174|Actinobacteria,4CU0W@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_65	1120949.KB903339_gene8067	7.915e-64	222.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4DDBF@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158462_k127_2993191_101	1306174.JODP01000029_gene3836	2.128e-30	129.0	COG1917@1|root,COG1917@2|Bacteria,2IT36@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_2993191_91	666685.R2APBS1_2352	1.425e-36	147.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1X6DF@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158462_k127_2993191_96	469383.Cwoe_2685	1.618e-33	135.0	COG1917@1|root,COG1917@2|Bacteria,2H15W@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_2993191_81	1380390.JIAT01000009_gene1188	2.118e-46	174.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4CRV8@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_6	1380390.JIAT01000001_gene5062	7.494e-193	612.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4CRDZ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158462_k127_2993191_116	1121946.AUAX01000017_gene5078	1.565e-16	93.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria,4DJGB@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158462_k127_2993191_112	66897.DJ64_23560	2.121e-19	90.0	2EVKU@1|root,33P0V@2|Bacteria,2IQJK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_86	487521.OCU_48580	6.695e-42	161.0	COG0586@1|root,COG0586@2|Bacteria,2GN4A@201174|Actinobacteria,23924@1762|Mycobacteriaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158462_k127_2993191_139	1380380.JIAX01000011_gene2373	5.781e-05	55.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG2755 Lysophospholipase L1 and related esterases	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
SRR25158462_k127_2993191_26	469383.Cwoe_0765	1.58e-131	433.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4CPDS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158462_k127_2993191_79	469383.Cwoe_2985	5.668e-47	182.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_2993191_67	243090.RB5332	9.276e-62	221.0	COG2129@1|root,COG2129@2|Bacteria,2J1K1@203682|Planctomycetes	203682|Planctomycetes	S	Metallophosphoesterase, calcineurin superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158462_k127_2993191_129	266117.Rxyl_1005	1.66e-08	69.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_5	469383.Cwoe_4511	2.611e-193	619.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_2993191_31	1463858.JOHR01000003_gene1974	1.119e-111	368.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria	201174|Actinobacteria	K	aldo keto reductase	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158462_k127_2993191_54	1449346.JQMO01000003_gene2208	4.091e-73	254.0	arCOG10607@1|root,30Y0T@2|Bacteria,2I8NG@201174|Actinobacteria,2M3Z0@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_2993191_35	469383.Cwoe_1079	3.748e-101	340.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4CPAG@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_2993191_92	525368.HMPREF0591_3095	1.273e-35	140.0	COG3832@1|root,COG3832@2|Bacteria,2ISDQ@201174|Actinobacteria,23FFB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158462_k127_2993191_34	469383.Cwoe_3526	9.493e-103	350.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158462_k127_2993191_127	1463917.JODC01000014_gene1967	8.705e-10	71.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_2993191_42	1121920.AUAU01000018_gene1825	2.227e-88	310.0	COG0514@1|root,COG0514@2|Bacteria,3Y2KM@57723|Acidobacteria	57723|Acidobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RecQ_Zn_bind
SRR25158462_k127_2993191_43	1380390.JIAT01000017_gene5262	2.138e-84	293.0	COG0672@1|root,COG2822@1|root,COG0672@2|Bacteria,COG2822@2|Bacteria,2GJPY@201174|Actinobacteria,4CU3J@84995|Rubrobacteria	84995|Rubrobacteria	P	Imelysin	-	-	-	ko:K07224	-	-	-	-	ko00000,ko02000	2.A.108.2.3	-	-	Cupredoxin_1,Peptidase_M75
SRR25158462_k127_2993191_18	1380390.JIAT01000009_gene2179	2.785e-144	468.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4CP9V@84995|Rubrobacteria	84995|Rubrobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
SRR25158462_k127_2993191_7	1440774.Y900_023750	4.108e-180	576.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,2334D@1762|Mycobacteriaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158462_k127_2993191_10	262316.MAP_2670c	3.189e-157	501.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,232XI@1762|Mycobacteriaceae	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd2	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1122	6PGD,NAD_binding_2
SRR25158462_k127_2993191_71	404589.Anae109_0599	2.674e-55	204.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase	pgl	-	2.7.1.12,3.1.1.31	ko:K00851,ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R01737,R02035	RC00002,RC00017,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158462_k127_2993191_30	1380390.JIAT01000016_gene5479	5.394e-118	395.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4CQZT@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158462_k127_2993191_53	1283299.AUKG01000002_gene3980	2.835e-73	255.0	COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CQAP@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158462_k127_2993191_3	253839.SSNG_05648	2.217e-231	728.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158462_k127_2993191_131	1150599.MPHLEI_20979	5.986e-08	62.0	COG1716@1|root,COG1716@2|Bacteria,2HPF7@201174|Actinobacteria,2351W@1762|Mycobacteriaceae	201174|Actinobacteria	T	Fha domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,FHA
SRR25158462_k127_2993191_126	469383.Cwoe_0508	5.193e-10	71.0	COG2931@1|root,COG2931@2|Bacteria,2IPR5@201174|Actinobacteria,4CS6K@84995|Rubrobacteria	84995|Rubrobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158462_k127_2993191_119	208439.AJAP_22955	2.973e-16	90.0	COG0823@1|root,COG2304@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,2GMNT@201174|Actinobacteria,4DXHJ@85010|Pseudonocardiales	201174|Actinobacteria	U	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PD40,VWA
SRR25158462_k127_2993191_41	1283299.AUKG01000001_gene3236	8.633e-89	321.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRJD@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158462_k127_2993191_1	483219.LILAB_09625	6.772e-278	870.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158462_k127_2993191_25	196490.AUEZ01000002_gene4236	2.623e-133	436.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,2U10P@28211|Alphaproteobacteria,3JWNC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158462_k127_2993191_37	749414.SBI_00351	1.041e-92	327.0	COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158462_k127_3018933_1	1121918.ARWE01000001_gene3390	2.955e-32	132.0	COG2963@1|root,COG2963@2|Bacteria,1N2YP@1224|Proteobacteria,42UQF@68525|delta/epsilon subdivisions,2WQSZ@28221|Deltaproteobacteria,43V1K@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
SRR25158462_k127_3018933_0	765912.Thimo_1421	3.403e-42	163.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria,1WWFP@135613|Chromatiales	135613|Chromatiales	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve
SRR25158462_k127_3037083_0	1283299.AUKG01000001_gene1591	1.581e-44	179.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158462_k127_3060471_49	469383.Cwoe_1036	3.075e-07	52.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,4CTD9@84995|Rubrobacteria	84995|Rubrobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158462_k127_3060471_2	469383.Cwoe_5162	3.096e-252	794.0	COG2015@1|root,COG2015@2|Bacteria,2GK38@201174|Actinobacteria	201174|Actinobacteria	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
SRR25158462_k127_3060471_40	1906.SFRA_28835	4.833e-22	112.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3060471_17	1380390.JIAT01000011_gene2324	9.579e-105	362.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4CTG0@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158462_k127_3060471_30	208444.JNYY01000020_gene4533	2.049e-57	222.0	COG2220@1|root,COG2220@2|Bacteria,2GN98@201174|Actinobacteria,4E2GG@85010|Pseudonocardiales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158462_k127_3060471_3	469383.Cwoe_2964	9.246e-251	806.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRR25158462_k127_3060471_10	1380390.JIAT01000011_gene2320	7.723e-162	522.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4CR6A@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158462_k127_3060471_1	469383.Cwoe_3076	6.577e-303	946.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CPJ0@84995|Rubrobacteria	84995|Rubrobacteria	HI	1-deoxy-D-xylulose-5-phosphate synthase	-	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158462_k127_3060471_18	1283299.AUKG01000002_gene5321	2.391e-102	346.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4CP7H@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158462_k127_3060471_37	1283299.AUKG01000002_gene5327	1.37e-33	133.0	COG0781@1|root,COG0781@2|Bacteria,2HP01@201174|Actinobacteria,4CQ9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158462_k127_3060471_47	469383.Cwoe_1428	9.552e-10	73.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
SRR25158462_k127_3060471_48	1449346.JQMO01000003_gene3691	7.832e-08	66.0	COG3291@1|root,COG3291@2|Bacteria,2H23D@201174|Actinobacteria	201174|Actinobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3060471_26	1380390.JIAT01000003_gene5432	1.167e-76	260.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CPH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158462_k127_3060471_33	1283299.AUKG01000001_gene2300	4.831e-50	204.0	COG0642@1|root,COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria,4CQ08@84995|Rubrobacteria	84995|Rubrobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TetR_N
SRR25158462_k127_3060471_22	469383.Cwoe_4168	1.145e-94	319.0	COG0300@1|root,COG0300@2|Bacteria,2HF4X@201174|Actinobacteria,4CR1X@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_3060471_14	929712.KI912613_gene2770	2.66e-135	445.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4CSJZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158462_k127_3060471_15	469383.Cwoe_0999	6.018e-128	417.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158462_k127_3060471_29	1283299.AUKG01000004_gene957	1.91e-66	244.0	COG2199@1|root,COG3706@2|Bacteria,2HFSA@201174|Actinobacteria,4CS6M@84995|Rubrobacteria	84995|Rubrobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158462_k127_3060471_16	469383.Cwoe_3060	1.216e-110	369.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CPI6@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158462_k127_3060471_32	929712.KI912613_gene3456	4.168e-50	182.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CQJK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158462_k127_3060471_13	469383.Cwoe_3058	7.572e-140	477.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CPMA@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158462_k127_3060471_9	1380390.JIAT01000017_gene5276	6.35e-176	559.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CPJG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158462_k127_3060471_27	469383.Cwoe_3037	1.023e-74	259.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CQ8W@84995|Rubrobacteria	84995|Rubrobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158462_k127_3060471_21	469383.Cwoe_3036	1.753e-97	335.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CQ8A@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158462_k127_3060471_39	1283299.AUKG01000004_gene970	3.323e-24	111.0	COG0816@1|root,COG0816@2|Bacteria,2HPE8@201174|Actinobacteria,4CQSC@84995|Rubrobacteria	84995|Rubrobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158462_k127_3060471_0	469383.Cwoe_3034	5.613e-312	978.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158462_k127_3060471_12	469383.Cwoe_3019	3.921e-140	465.0	COG0482@1|root,COG0822@1|root,COG0482@2|Bacteria,COG0822@2|Bacteria,2GIUQ@201174|Actinobacteria,4CPQ6@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	NifU_N,tRNA_Me_trans
SRR25158462_k127_3060471_8	1392502.JNIO01000008_gene1875	1.289e-198	635.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4H32N@909932|Negativicutes	909932|Negativicutes	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
SRR25158462_k127_3060471_11	469383.Cwoe_3015	1.082e-146	475.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CPRI@84995|Rubrobacteria	84995|Rubrobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158462_k127_3060471_23	1380390.JIAT01000017_gene5310	1.34e-91	305.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4CQ06@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_3060471_28	1122939.ATUD01000005_gene2591	4.884e-72	253.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CPTU@84995|Rubrobacteria	84995|Rubrobacteria	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158462_k127_3060471_24	469383.Cwoe_3010	1.385e-88	302.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
SRR25158462_k127_3060471_50	658086.HMPREF0994_01852	3.125e-06	59.0	2EAYB@1|root,334ZB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3060471_45	693661.Arcve_0735	5.847e-11	67.0	arCOG03086@1|root,arCOG03086@2157|Archaea,2Y6GQ@28890|Euryarchaeota,247DW@183980|Archaeoglobi	183980|Archaeoglobi	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158462_k127_3060471_44	65093.PCC7418_1702	3.697e-12	68.0	COG1598@1|root,COG1598@2|Bacteria,1G94Z@1117|Cyanobacteria	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
SRR25158462_k127_3060471_38	1283299.AUKG01000004_gene1085	1.314e-27	115.0	arCOG11477@1|root,32TJG@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158462_k127_3060471_4	1380390.JIAT01000010_gene4392	7.404e-240	775.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158462_k127_3060471_31	469383.Cwoe_5886	5.555e-52	203.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4CQCM@84995|Rubrobacteria	84995|Rubrobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158462_k127_3060471_41	1229780.BN381_330001	7.933e-17	94.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,2IFXI@201174|Actinobacteria	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SRR25158462_k127_3060471_34	526225.Gobs_1802	1.594e-47	178.0	COG0664@1|root,COG1651@1|root,COG3004@1|root,COG0664@2|Bacteria,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4ESBH@85013|Frankiales	201174|Actinobacteria	OP	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158462_k127_3060471_19	469383.Cwoe_4979	2.434e-102	351.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CR9E@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158462_k127_3060471_25	1463920.JOGB01000053_gene5026	1.389e-84	289.0	COG0596@1|root,COG0596@2|Bacteria,2I1Q9@201174|Actinobacteria	201174|Actinobacteria	EGP	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158462_k127_3060471_20	1313265.JNIE01000004_gene589	1.108e-98	338.0	COG0498@1|root,COG0498@2|Bacteria,2G4SE@200783|Aquificae	200783|Aquificae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC_1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158462_k127_3060471_46	706587.Desti_0590	1.956e-10	64.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,42X7S@68525|delta/epsilon subdivisions,2WSVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_3060471_5	469383.Cwoe_1538	1.297e-232	741.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158462_k127_3060471_35	1122939.ATUD01000013_gene903	9.046e-38	146.0	COG2246@1|root,COG2246@2|Bacteria,2HR1U@201174|Actinobacteria,4CSWB@84995|Rubrobacteria	84995|Rubrobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158462_k127_3060471_7	1283299.AUKG01000004_gene1073	1.52e-221	701.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPH0@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158462_k127_3060471_6	469383.Cwoe_2921	1.248e-225	741.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CPT4@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158462_k127_3082129_4	929712.KI912613_gene2882	2.938e-149	479.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CP9Y@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158462_k127_3082129_9	469383.Cwoe_4619	5.653e-104	346.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CPD1@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158462_k127_3082129_1	1380390.JIAT01000009_gene342	2.34e-243	762.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CP6C@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158462_k127_3082129_16	469383.Cwoe_4621	2.097e-57	207.0	COG0712@1|root,COG0712@2|Bacteria,2HNXP@201174|Actinobacteria,4CQ6B@84995|Rubrobacteria	84995|Rubrobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158462_k127_3082129_17	1380390.JIAT01000009_gene344	3.264e-52	190.0	COG0711@1|root,COG0711@2|Bacteria,2HGFF@201174|Actinobacteria,4CQKE@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158462_k127_3082129_22	1380390.JIAT01000009_gene345	5.858e-27	113.0	COG0636@1|root,COG0636@2|Bacteria,2HPGR@201174|Actinobacteria,4CQV2@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158462_k127_3082129_10	1380390.JIAT01000009_gene346	1.879e-101	339.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CR6B@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase A chain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_A
SRR25158462_k127_3082129_23	469383.Cwoe_4625	2.589e-08	64.0	2A1TX@1|root,30Q2V@2|Bacteria,2HR8N@201174|Actinobacteria,4CT50@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3082129_8	469383.Cwoe_4628	3.207e-115	384.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CQIN@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase, family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158462_k127_3082129_0	1380390.JIAT01000009_gene364	2.733e-253	797.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158462_k127_3082129_20	469383.Cwoe_3048	1.525e-38	151.0	COG1437@1|root,COG1437@2|Bacteria,2I6ID@201174|Actinobacteria,4CQCZ@84995|Rubrobacteria	84995|Rubrobacteria	F	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
SRR25158462_k127_3082129_13	1380390.JIAT01000009_gene363	9.41e-72	259.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria	201174|Actinobacteria	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158462_k127_3082129_6	1380390.JIAT01000009_gene362	3.33e-133	433.0	COG1817@1|root,COG1817@2|Bacteria,2HQP4@201174|Actinobacteria,4CSA7@84995|Rubrobacteria	2|Bacteria	S	Protein of unknown function (DUF354)	-	-	-	ko:K09726	-	-	-	-	ko00000	-	-	-	DUF354
SRR25158462_k127_3082129_2	266117.Rxyl_0469	1.252e-214	673.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CPC6@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158462_k127_3082129_19	1122939.ATUD01000001_gene328	1.137e-41	175.0	2EN03@1|root,33FN9@2|Bacteria,2HNYF@201174|Actinobacteria,4CQ7V@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
SRR25158462_k127_3082129_18	1380390.JIAT01000009_gene368	1.184e-43	168.0	COG0009@1|root,COG0009@2|Bacteria,2HPE4@201174|Actinobacteria,4CQS7@84995|Rubrobacteria	84995|Rubrobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158462_k127_3082129_14	469383.Cwoe_4634	4.052e-62	226.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158462_k127_3082129_7	266117.Rxyl_1652	3.489e-122	401.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CP8A@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158462_k127_3082129_5	1380390.JIAT01000009_gene371	2.739e-136	441.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158462_k127_3082129_21	525909.Afer_1810	7.976e-28	116.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CP0K@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158462_k127_3082129_11	469383.Cwoe_2934	1.227e-76	274.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CPWX@84995|Rubrobacteria	84995|Rubrobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD_5
SRR25158462_k127_3082129_15	1283299.AUKG01000001_gene2935	2.17e-58	209.0	COG1309@1|root,COG1309@2|Bacteria,2GNR9@201174|Actinobacteria,4CQDU@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_3082129_12	1068980.ARVW01000001_gene2593	2.691e-73	257.0	COG2267@1|root,COG2267@2|Bacteria,2HJ2M@201174|Actinobacteria,4E33U@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158462_k127_3082129_3	1380390.JIAT01000009_gene374	9.693e-155	499.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,2HQ59@201174|Actinobacteria,4CRNF@84995|Rubrobacteria	84995|Rubrobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
SRR25158462_k127_3103630_0	42256.RradSPS_2114	2.042e-135	441.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158462_k127_3103630_1	42256.RradSPS_2113	4.857e-71	252.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158462_k127_3103630_2	42256.RradSPS_2112	1.153e-69	258.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158462_k127_3117441_5	1380390.JIAT01000010_gene4136	8.477e-41	169.0	2ETCF@1|root,33KWB@2|Bacteria,2HQ8W@201174|Actinobacteria,4CRSS@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
SRR25158462_k127_3117441_0	469383.Cwoe_1884	8.756e-274	854.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CPJN@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158462_k127_3117441_1	1149133.ppKF707_6158	2.855e-107	362.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1YFGX@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158462_k127_3117441_4	1380390.JIAT01000014_gene6086	5.884e-43	169.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CQGC@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158462_k127_3117441_2	1380390.JIAT01000014_gene6087	6.84e-71	243.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CQAX@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158462_k127_3117441_3	469383.Cwoe_1880	2.017e-50	191.0	COG0739@1|root,COG0739@2|Bacteria,2HP3A@201174|Actinobacteria,4CQEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M23
SRR25158462_k127_3117441_6	1283299.AUKG01000003_gene331	1.099e-22	106.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRHR@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_3129448_15	1380390.JIAT01000016_gene5642	1.258e-37	144.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4CQG8@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158462_k127_3129448_1	469383.Cwoe_3105	2.33e-133	434.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CPM8@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158462_k127_3129448_0	469383.Cwoe_3106	5.991e-135	459.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CPNK@84995|Rubrobacteria	84995|Rubrobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158462_k127_3129448_2	469383.Cwoe_3114	8.488e-108	364.0	COG1819@1|root,COG1819@2|Bacteria,2I8EN@201174|Actinobacteria,4CPRE@84995|Rubrobacteria	84995|Rubrobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158462_k127_3129448_6	1283299.AUKG01000002_gene5281	1.006e-88	300.0	COG4221@1|root,COG4221@2|Bacteria,2I5BD@201174|Actinobacteria,4CPN3@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_3129448_10	469383.Cwoe_4202	8.373e-64	236.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3129448_13	1298863.AUEP01000005_gene2505	1.055e-49	189.0	COG5002@1|root,COG5002@2|Bacteria,2IMZ1@201174|Actinobacteria	201174|Actinobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4
SRR25158462_k127_3129448_16	1283299.AUKG01000002_gene3929	3.09e-35	142.0	COG0711@1|root,COG0711@2|Bacteria,2HP0U@201174|Actinobacteria,4CQAI@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3129448_19	1298880.AUEV01000008_gene2293	5.123e-14	82.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158462_k127_3129448_12	1380390.JIAT01000010_gene3987	9.225e-50	183.0	29S2G@1|root,30D6Y@2|Bacteria,2HR27@201174|Actinobacteria,4CSWZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158462_k127_3129448_4	1499967.BAYZ01000014_gene6360	1.109e-104	361.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
SRR25158462_k127_3129448_7	1121423.JONT01000001_gene1855	4.7e-86	303.0	COG0849@1|root,COG0849@2|Bacteria,1TQC5@1239|Firmicutes,24BFJ@186801|Clostridia,2605E@186807|Peptococcaceae	186801|Clostridia	D	TIGRFAM conserved	mutL2	-	-	-	-	-	-	-	-	-	-	-	MutL
SRR25158462_k127_3129448_8	357808.RoseRS_4338	1.466e-84	291.0	COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi	200795|Chloroflexi	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3129448_14	383372.Rcas_0129	1.841e-48	193.0	COG0531@1|root,COG0531@2|Bacteria,2G76Z@200795|Chloroflexi	200795|Chloroflexi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158462_k127_3129448_11	309801.trd_1320	7.628e-55	202.0	arCOG06048@1|root,31EJQ@2|Bacteria,2G6TM@200795|Chloroflexi,27Z2Z@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3129448_20	1028307.EAE_17390	3.475e-07	60.0	COG1309@1|root,COG1309@2|Bacteria,1R5GP@1224|Proteobacteria,1RR01@1236|Gammaproteobacteria,3X07Y@547|Enterobacter	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	tetC	-	-	ko:K19047	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158462_k127_3129448_3	1118054.CAGW01000061_gene2441	2.791e-107	363.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,275V3@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158462_k127_3129448_17	469383.Cwoe_4699	3.372e-34	134.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4CQ0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158462_k127_3129448_5	1283299.AUKG01000001_gene2315	2.925e-93	325.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4CRQE@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158462_k127_3129448_9	1122939.ATUD01000011_gene2240	1.757e-67	250.0	COG4325@1|root,COG4325@2|Bacteria,2GM70@201174|Actinobacteria,4CSZ9@84995|Rubrobacteria	84995|Rubrobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3129448_22	710111.FraQA3DRAFT_3658	2.322e-06	60.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158462_k127_3129448_21	653045.Strvi_1696	1.253e-06	59.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3129448_18	469383.Cwoe_3158	8.058e-25	106.0	COG1737@1|root,COG1737@2|Bacteria,2HGPB@201174|Actinobacteria,4CPA9@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158462_k127_313284_0	596152.DesU5LDRAFT_2681	1.066e-27	113.0	2DN97@1|root,32W7A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_313284_4	1069080.KB913028_gene217	5.847e-10	61.0	2DREN@1|root,33BEG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_313284_6	929794.CALV01000065_gene1616	0.0002045	45.0	2E4EA@1|root,32Z9I@2|Bacteria,1PWSF@1224|Proteobacteria,2V587@28211|Alphaproteobacteria,48UAE@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3144281_4	1121028.ARQE01000001_gene3521	5.038e-131	422.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,2PJDR@255475|Aurantimonadaceae	28211|Alphaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158462_k127_3144281_26	1283299.AUKG01000002_gene3891	8.181e-31	125.0	COG0355@1|root,COG0355@2|Bacteria,2HPEY@201174|Actinobacteria,4CQTA@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158462_k127_3144281_2	469383.Cwoe_4616	2.441e-144	467.0	COG0624@1|root,COG0624@2|Bacteria,2I9GD@201174|Actinobacteria,4CPM7@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158462_k127_3144281_11	1283299.AUKG01000002_gene3898	7.97e-95	333.0	COG1316@1|root,COG1316@2|Bacteria,2HJ7K@201174|Actinobacteria,4CPJT@84995|Rubrobacteria	84995|Rubrobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158462_k127_3144281_5	525904.Tter_0698	1.64e-121	403.0	COG1004@1|root,COG1004@2|Bacteria,2NNYN@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ywqF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.132,1.1.1.22	ko:K00012,ko:K00066	ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020	M00014,M00129,M00361,M00362	R00286,R00880	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158462_k127_3144281_10	1380390.JIAT01000009_gene330	4.197e-95	329.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158462_k127_3144281_9	469383.Cwoe_4612	5.821e-97	327.0	COG2222@1|root,COG2222@2|Bacteria,2IN5A@201174|Actinobacteria,4CP71@84995|Rubrobacteria	84995|Rubrobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
SRR25158462_k127_3144281_8	1122939.ATUD01000020_gene2152	5.958e-105	351.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPY2@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158462_k127_3144281_24	469383.Cwoe_4601	1.974e-33	139.0	COG1040@1|root,COG1040@2|Bacteria,2HP3J@201174|Actinobacteria,4CQES@84995|Rubrobacteria	84995|Rubrobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158462_k127_3144281_27	469383.Cwoe_4600	3.681e-25	109.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CQU6@84995|Rubrobacteria	84995|Rubrobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158462_k127_3144281_0	471852.Tcur_4035	4.183e-285	903.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4EGCZ@85012|Streptosporangiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158462_k127_3144281_17	1123229.AUBC01000030_gene1377	6.683e-72	252.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	MA20_37085	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
SRR25158462_k127_3144281_1	469383.Cwoe_4596	1.038e-148	481.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CPCP@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158462_k127_3144281_15	469383.Cwoe_1983	1.908e-83	281.0	COG0400@1|root,COG0400@2|Bacteria,2GZKY@201174|Actinobacteria,4CPVW@84995|Rubrobacteria	84995|Rubrobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158462_k127_3144281_20	31964.CMS0818	1.678e-57	213.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4FNS0@85023|Microbacteriaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158462_k127_3144281_22	1283299.AUKG01000001_gene3249	3.648e-50	182.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4CSB0@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_3144281_13	469383.Cwoe_4594	1.862e-85	291.0	COG0157@1|root,COG0157@2|Bacteria,2I2IP@201174|Actinobacteria,4CU2Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
SRR25158462_k127_3144281_6	1380390.JIAT01000009_gene1194	3.33e-109	360.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4CPDC@84995|Rubrobacteria	84995|Rubrobacteria	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH
SRR25158462_k127_3144281_3	1283299.AUKG01000002_gene3936	4.089e-141	467.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4CP6W@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158462_k127_3144281_25	290512.Paes_0464	9.975e-32	131.0	COG2010@1|root,COG2010@2|Bacteria,1FEAI@1090|Chlorobi	1090|Chlorobi	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
SRR25158462_k127_3144281_21	1001240.GY21_12265	1.27e-52	213.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria,4FTR6@85023|Microbacteriaceae	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158462_k127_3144281_19	1370121.AUWS01000023_gene2291	7.549e-66	232.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,234EX@1762|Mycobacteriaceae	201174|Actinobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_3144281_16	1380390.JIAT01000014_gene6283	1.145e-75	265.0	COG1477@1|root,COG1477@2|Bacteria,2HQ3C@201174|Actinobacteria,4CRJW@84995|Rubrobacteria	84995|Rubrobacteria	H	ApbE family	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
SRR25158462_k127_3144281_23	1380390.JIAT01000014_gene6282	1.844e-33	147.0	COG4097@1|root,COG4097@2|Bacteria,2HPUY@201174|Actinobacteria,4CR8R@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
SRR25158462_k127_3144281_12	469383.Cwoe_4587	1.65e-93	334.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CPHA@84995|Rubrobacteria	84995|Rubrobacteria	D	ATPases associated with a variety of cellular activities	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158462_k127_3144281_18	469383.Cwoe_4586	6.717e-66	238.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CPSH@84995|Rubrobacteria	84995|Rubrobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158462_k127_3144281_14	1380390.JIAT01000001_gene5115	7.055e-84	292.0	COG0793@1|root,COG0793@2|Bacteria,2GKRP@201174|Actinobacteria,4CPMI@84995|Rubrobacteria	84995|Rubrobacteria	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158462_k127_3144281_7	1283299.AUKG01000002_gene3947	4.078e-105	371.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CPE0@84995|Rubrobacteria	84995|Rubrobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158462_k127_3216844_3	203119.Cthe_0381	3.833e-08	54.0	28SHS@1|root,2ZEU4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3216844_0	93220.LV28_12140	1.349e-138	448.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VJJ7@28216|Betaproteobacteria,1K2F0@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_38,HTH_7,rve
SRR25158462_k127_3216844_1	1458357.BG58_06830	8.722e-120	392.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VMBN@28216|Betaproteobacteria,1K27P@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158462_k127_3216844_2	204773.HEAR2109	1.408e-18	87.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VP1R@28216|Betaproteobacteria,474QT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158462_k127_322272_1	985867.AEWF01000006_gene496	1.771e-36	143.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria,47G6G@766|Rickettsiales	766|Rickettsiales	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_322272_3	663932.KB902575_gene1346	3.47e-20	91.0	2DPT9@1|root,333A8@2|Bacteria,1NFKV@1224|Proteobacteria,2UUAG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_322272_0	1089548.KI783301_gene3307	1.255e-39	151.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,4IRDZ@91061|Bacilli	91061|Bacilli	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_322272_2	1150469.RSPPHO_03279	1.518e-23	102.0	2DTV2@1|root,33MS7@2|Bacteria,1NKAB@1224|Proteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235833_1	926550.CLDAP_19690	2.881e-246	775.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158462_k127_3235833_9	1121378.KB899706_gene1553	1.16e-29	122.0	COG4270@1|root,COG4270@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158462_k127_3235833_13	1173027.Mic7113_0824	2.415e-07	58.0	COG3620@1|root,COG3620@2|Bacteria,1G9PF@1117|Cyanobacteria,1HD6T@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_3235833_12	1283287.KB822582_gene2954	1.979e-12	77.0	2B6JB@1|root,31ZHQ@2|Bacteria,2II7G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235833_5	1048339.KB913029_gene2334	3.137e-107	364.0	COG0477@1|root,COG0477@2|Bacteria,2IDYF@201174|Actinobacteria,4EUIS@85013|Frankiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_3235833_7	1122939.ATUD01000002_gene1468	1.174e-45	178.0	COG0741@1|root,COG0741@2|Bacteria,2GWDB@201174|Actinobacteria,4CQ5G@84995|Rubrobacteria	84995|Rubrobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
SRR25158462_k127_3235833_6	1380390.JIAT01000016_gene5588	1.003e-49	183.0	COG0237@1|root,COG0237@2|Bacteria,2HG2S@201174|Actinobacteria,4CQK0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158462_k127_3235833_2	469383.Cwoe_2872	9.333e-192	612.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CPF8@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158462_k127_3235833_3	469383.Cwoe_2871	9.478e-168	537.0	COG0644@1|root,COG0644@2|Bacteria,2HQ8K@201174|Actinobacteria,4CRS9@84995|Rubrobacteria	84995|Rubrobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235833_8	1380390.JIAT01000016_gene5594	8.209e-30	124.0	COG3238@1|root,COG3238@2|Bacteria,2HQYP@201174|Actinobacteria,4CSRF@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
SRR25158462_k127_3235833_10	1283299.AUKG01000004_gene1138	3.394e-29	132.0	COG1595@1|root,COG1595@2|Bacteria,2HQH8@201174|Actinobacteria,4CS2B@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_3235833_14	649831.L083_2849	4.862e-07	60.0	COG3266@1|root,COG3266@2|Bacteria,2GW3B@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235833_0	469383.Cwoe_2867	1.25e-311	977.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRR25158462_k127_3235833_4	469383.Cwoe_3786	7.169e-114	383.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5
SRR25158462_k127_3235833_11	1380390.JIAT01000014_gene6260	2.604e-19	92.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_3235839_29	1283299.AUKG01000001_gene1591	4.897e-39	169.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158462_k127_3235839_42	469383.Cwoe_1428	0.0001465	56.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
SRR25158462_k127_3235839_40	521011.Mpal_1345	2.363e-17	98.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158462_k127_3235839_1	469383.Cwoe_4526	6.007e-193	616.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4CPQY@84995|Rubrobacteria	84995|Rubrobacteria	L	type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
SRR25158462_k127_3235839_14	443255.SCLAV_3084	3.352e-97	334.0	COG0017@1|root,COG0017@2|Bacteria,2I2KQ@201174|Actinobacteria	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158462_k127_3235839_25	134676.ACPL_2187	1.486e-61	225.0	COG2175@1|root,COG2175@2|Bacteria,2GSEY@201174|Actinobacteria,4DGBY@85008|Micromonosporales	201174|Actinobacteria	C	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.39	ko:K18058	-	-	-	-	ko00000,ko01000	-	-	-	TauD
SRR25158462_k127_3235839_12	330084.JNYZ01000012_gene7637	5.574e-102	341.0	2C75R@1|root,2ZCK5@2|Bacteria,2IBVD@201174|Actinobacteria,4E8JR@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235839_18	189753.AXAS01000003_gene4860	3.124e-75	257.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,3JR7C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	MA20_22790	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158462_k127_3235839_31	469383.Cwoe_3660	1.906e-37	152.0	COG0328@1|root,COG0328@2|Bacteria,2I4IN@201174|Actinobacteria	201174|Actinobacteria	L	Reverse transcriptase-like	-	-	3.1.26.4,3.1.3.73	ko:K03469,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Glyoxalase_4,His_Phos_1,RVT_3
SRR25158462_k127_3235839_39	1380390.JIAT01000010_gene4284	7.848e-18	97.0	2AT5U@1|root,31IN3@2|Bacteria,2HN2Z@201174|Actinobacteria,4CQH5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235839_9	469383.Cwoe_3664	8.65e-113	368.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158462_k127_3235839_11	1283299.AUKG01000002_gene4772	5.4e-102	344.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CSHN@84995|Rubrobacteria	84995|Rubrobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158462_k127_3235839_10	469383.Cwoe_3666	5.233e-103	346.0	COG1376@1|root,COG1376@2|Bacteria,2HPTN@201174|Actinobacteria,4CR7H@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158462_k127_3235839_26	1455608.JDTH01000001_gene3685	3.958e-60	220.0	COG0212@1|root,arCOG00474@2157|Archaea,2XTN7@28890|Euryarchaeota,23S39@183963|Halobacteria	183963|Halobacteria	H	5-formyltetrahydrofolate cycloligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158462_k127_3235839_22	469383.Cwoe_3668	1.987e-69	248.0	COG2267@1|root,COG2267@2|Bacteria,2GM96@201174|Actinobacteria,4CTEF@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235839_0	1380390.JIAT01000010_gene4273	1.665e-232	738.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CPCE@84995|Rubrobacteria	84995|Rubrobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158462_k127_3235839_13	469383.Cwoe_3672	9.104e-98	325.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CQ3U@84995|Rubrobacteria	84995|Rubrobacteria	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR25158462_k127_3235839_21	469383.Cwoe_3673	7.83e-70	251.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CQDE@84995|Rubrobacteria	84995|Rubrobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158462_k127_3235839_7	1283299.AUKG01000002_gene4758	2.252e-130	438.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4CPKF@84995|Rubrobacteria	84995|Rubrobacteria	O	magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158462_k127_3235839_35	929712.KI912613_gene4184	4.953e-25	108.0	COG0792@1|root,COG0792@2|Bacteria,2HP2Y@201174|Actinobacteria,4CQE0@84995|Rubrobacteria	84995|Rubrobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158462_k127_3235839_16	469383.Cwoe_3676	1.858e-78	269.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CQ01@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158462_k127_3235839_17	469383.Cwoe_3677	1.904e-77	267.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158462_k127_3235839_27	1380390.JIAT01000010_gene4261	1.754e-56	208.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CQ3H@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158462_k127_3235839_15	469383.Cwoe_3679	3.677e-94	313.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CPQ4@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158462_k127_3235839_36	1283299.AUKG01000002_gene4749	2.319e-20	93.0	COG1837@1|root,COG1837@2|Bacteria,2HNEK@201174|Actinobacteria,4CQQV@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158462_k127_3235839_33	469383.Cwoe_3682	1.572e-28	118.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CQNJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158462_k127_3235839_6	926692.AZYG01000059_gene122	2.343e-160	517.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WAIA@53433|Halanaerobiales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158462_k127_3235839_8	1380390.JIAT01000010_gene4252	1.172e-124	407.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CPF9@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158462_k127_3235839_5	469383.Cwoe_3688	1.211e-174	575.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158462_k127_3235839_24	469383.Cwoe_3689	6.484e-62	220.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CPZ4@84995|Rubrobacteria	84995|Rubrobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158462_k127_3235839_34	1283299.AUKG01000002_gene4738	1.899e-26	109.0	COG0236@1|root,COG0236@2|Bacteria,2HNF1@201174|Actinobacteria,4CQR2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158462_k127_3235839_19	469383.Cwoe_3691	1.506e-74	266.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CQB5@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158462_k127_3235839_38	469383.Cwoe_3692	2.712e-18	92.0	COG0333@1|root,COG0333@2|Bacteria,2HPDQ@201174|Actinobacteria,4CQRN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158462_k127_3235839_32	1056816.JAFQ01000004_gene11	2.543e-35	141.0	COG0500@1|root,COG2226@2|Bacteria,2HJCZ@201174|Actinobacteria,4G6D4@85025|Nocardiaceae	2|Bacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158462_k127_3235839_28	469383.Cwoe_3693	1.13e-47	181.0	COG1399@1|root,COG1399@2|Bacteria,2HQSM@201174|Actinobacteria,4CSGR@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158462_k127_3235839_41	469371.Tbis_2629	5.483e-07	56.0	COG2852@1|root,COG2852@2|Bacteria,2II5Q@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559,TIR_2
SRR25158462_k127_3235839_20	469383.Cwoe_3698	1.138e-72	248.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3235839_23	469383.Cwoe_3699	2.58e-62	221.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CQ3G@84995|Rubrobacteria	84995|Rubrobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158462_k127_3235839_30	1321786.HMPREF1992_02320	7.748e-39	153.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes	1239|Firmicutes	L	RNA methyltransferase RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158462_k127_3235839_4	469383.Cwoe_3701	9.102e-184	617.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CPM1@84995|Rubrobacteria	84995|Rubrobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158462_k127_3235839_3	1380390.JIAT01000010_gene4222	1.836e-191	614.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CPUZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158462_k127_3235839_2	1306174.JODP01000001_gene5153	2.342e-192	625.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_3235839_37	1380390.JIAT01000014_gene6260	1.35e-18	91.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_3271803_0	1283299.AUKG01000001_gene1590	3.608e-109	371.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3274552_23	469383.Cwoe_1036	3.075e-07	52.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,4CTD9@84995|Rubrobacteria	84995|Rubrobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158462_k127_3274552_18	1463841.JOIR01000028_gene417	7.452e-25	111.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158462_k127_3274552_3	1283299.AUKG01000001_gene3043	1.458e-162	522.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158462_k127_3274552_14	1380390.JIAT01000014_gene6246	2.876e-70	248.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4CPNR@84995|Rubrobacteria	84995|Rubrobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
SRR25158462_k127_3274552_1	1394178.AWOO02000001_gene1514	1.214e-211	662.0	COG0183@1|root,COG0183@2|Bacteria,2IBJU@201174|Actinobacteria	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158462_k127_3274552_5	1283299.AUKG01000002_gene3973	2.692e-149	482.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_3274552_10	469383.Cwoe_0961	3.239e-85	309.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CRTX@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
SRR25158462_k127_3274552_13	2002.JOEQ01000005_gene3794	4.929e-73	266.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria,4EKB6@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158462_k127_3274552_17	469383.Cwoe_1040	3.978e-26	118.0	COG3695@1|root,COG3695@2|Bacteria,2HRG8@201174|Actinobacteria,4CTFC@84995|Rubrobacteria	84995|Rubrobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRR25158462_k127_3274552_21	1081644.IMCC13023_12750	2.627e-11	67.0	2BIUU@1|root,32D2U@2|Bacteria,2HTU3@201174|Actinobacteria,4FQIS@85023|Microbacteriaceae	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SRR25158462_k127_3274552_12	929712.KI912613_gene1711	7.29e-80	277.0	COG0491@1|root,COG0491@2|Bacteria,2IHG2@201174|Actinobacteria,4CTFT@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_3274552_19	1283299.AUKG01000001_gene3052	1.879e-16	85.0	2AUTJ@1|root,31KGM@2|Bacteria,2HPBH@201174|Actinobacteria,4CQPY@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3274552_9	469383.Cwoe_1779	8.743e-92	324.0	COG2247@1|root,COG2247@2|Bacteria,2I6I4@201174|Actinobacteria,4CU6H@84995|Rubrobacteria	84995|Rubrobacteria	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
SRR25158462_k127_3274552_7	1179773.BN6_83760	1.705e-125	415.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4DXQJ@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_3274552_15	42256.RradSPS_1158	4.276e-66	248.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CPWR@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158462_k127_3274552_4	469383.Cwoe_1791	2.344e-157	508.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CQ2U@84995|Rubrobacteria	84995|Rubrobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158462_k127_3274552_2	469383.Cwoe_1792	3.596e-166	531.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CPTX@84995|Rubrobacteria	84995|Rubrobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158462_k127_3274552_6	469383.Cwoe_1793	9.843e-145	466.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4CPKK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158462_k127_3274552_8	1283299.AUKG01000001_gene3074	5.195e-94	317.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CQEJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158462_k127_3274552_16	1120948.KB903243_gene2483	6.372e-34	134.0	2FE1I@1|root,3461R@2|Bacteria,2IRVY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3274552_11	1380390.JIAT01000011_gene2633	3.792e-80	295.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,Trans_reg_C
SRR25158462_k127_3274552_22	469383.Cwoe_1421	2.711e-10	66.0	COG4319@1|root,COG4319@2|Bacteria,2INZI@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158462_k127_3274552_24	1293047.CBMA010000025_gene1415	4.253e-06	54.0	arCOG03006@1|root,arCOG03006@2157|Archaea,2XYB4@28890|Euryarchaeota,23W8V@183963|Halobacteria	183963|Halobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_3274552_0	562970.Btus_1793	0.0	1246.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,2785F@186823|Alicyclobacillaceae	91061|Bacilli	E	Glutamate synthase central domain	gltA2	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158462_k127_3319670_0	864563.HMPREF9166_0005	6.252e-28	113.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes	1239|Firmicutes	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3319670_3	243230.DR_2252	1.376e-11	66.0	2ED08@1|root,33H8A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3319670_4	1423767.BALU01000025_gene2045	3.476e-06	48.0	2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae	91061|Bacilli	S	COG NOG38524 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3319670_1	1150469.RSPPHO_03264	7.1e-24	106.0	2EBGV@1|root,335HF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3320435_0	1380390.JIAT01000011_gene2452	4.776e-65	229.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4CS1Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
SRR25158462_k127_3320435_1	1121946.AUAX01000024_gene7631	1.118e-43	166.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4D9YV@85008|Micromonosporales	201174|Actinobacteria	G	COG1129 ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRR25158462_k127_3355968_26	1380390.JIAT01000017_gene5272	7.871e-17	94.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CU6W@84995|Rubrobacteria	84995|Rubrobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
SRR25158462_k127_3355968_1	1380390.JIAT01000010_gene4151	2.766e-172	546.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CP7W@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158462_k127_3355968_31	1380390.JIAT01000010_gene4150	1.91e-09	70.0	COG1589@1|root,COG1589@2|Bacteria,2HPRM@201174|Actinobacteria,4CR4Y@84995|Rubrobacteria	84995|Rubrobacteria	M	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158462_k127_3355968_17	401526.TcarDRAFT_0854	4.902e-57	215.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4H20N@909932|Negativicutes	909932|Negativicutes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158462_k127_3355968_12	561175.KB894098_gene5395	1.19e-95	329.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4EG2K@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158462_k127_3355968_8	469383.Cwoe_3770	3.03e-111	372.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CPNI@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158462_k127_3355968_10	469383.Cwoe_3771	3.331e-99	341.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CSTK@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158462_k127_3355968_4	1283299.AUKG01000002_gene4619	4.488e-144	471.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158462_k127_3355968_13	58344.JOEL01000036_gene4161	1.256e-77	269.0	COG2267@1|root,COG2267@2|Bacteria,2HJ2M@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158462_k127_3355968_5	469383.Cwoe_3773	5.292e-137	460.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CPF5@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158462_k127_3355968_9	1380390.JIAT01000010_gene4142	6.316e-105	357.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CPND@84995|Rubrobacteria	84995|Rubrobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158462_k127_3355968_3	469383.Cwoe_3774	5.426e-162	525.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CP75@84995|Rubrobacteria	84995|Rubrobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158462_k127_3355968_2	469383.Cwoe_3775	3.963e-171	554.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CPGN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158462_k127_3355968_32	469383.Cwoe_3776	2.163e-06	59.0	COG2919@1|root,COG2919@2|Bacteria,2HQXX@201174|Actinobacteria,4CSQC@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3355968_7	469383.Cwoe_3777	1.946e-117	395.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CPWG@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158462_k127_3355968_24	469383.Cwoe_3778	1.051e-24	112.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4CQT3@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158462_k127_3355968_27	929712.KI912613_gene3330	1.458e-14	87.0	COG2064@1|root,COG2064@2|Bacteria,2HMRR@201174|Actinobacteria,4CQEH@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158462_k127_3355968_19	469383.Cwoe_3781	8.322e-43	178.0	COG4965@1|root,COG4965@2|Bacteria	2|Bacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158462_k127_3355968_6	469383.Cwoe_3782	2.586e-122	405.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CR9H@84995|Rubrobacteria	84995|Rubrobacteria	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158462_k127_3355968_29	469383.Cwoe_3787	3.418e-10	72.0	COG3745@1|root,COG3745@2|Bacteria,2HP19@201174|Actinobacteria,4CQBK@84995|Rubrobacteria	84995|Rubrobacteria	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158462_k127_3355968_28	290397.Adeh_3855	2.317e-10	70.0	COG0642@1|root,COG2205@2|Bacteria,1QUJ5@1224|Proteobacteria,42NJC@68525|delta/epsilon subdivisions,2WW4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158462_k127_3355968_20	1380390.JIAT01000010_gene4090	8.732e-38	155.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_3355968_14	929712.KI912613_gene3325	4.214e-68	248.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CS4E@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_3355968_25	595537.Varpa_4927	4.18e-17	85.0	COG1430@1|root,COG1430@2|Bacteria,1N7U4@1224|Proteobacteria,2VWGX@28216|Betaproteobacteria,4AFXQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158462_k127_3355968_15	446462.Amir_4944	1.57e-67	250.0	COG1105@1|root,COG1105@2|Bacteria,2HJ3W@201174|Actinobacteria,4DZ7A@85010|Pseudonocardiales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158462_k127_3355968_21	929712.KI912613_gene2552	4.605e-33	137.0	COG4464@1|root,COG4464@2|Bacteria,2H0WF@201174|Actinobacteria,4CSZY@84995|Rubrobacteria	84995|Rubrobacteria	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158462_k127_3355968_16	469383.Cwoe_3792	1.223e-61	221.0	2AW02@1|root,31MUH@2|Bacteria,2HQH7@201174|Actinobacteria,4CS2A@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3355968_30	73044.JNXP01000009_gene2709	1.425e-09	68.0	COG1158@1|root,COG1158@2|Bacteria,2GIYY@201174|Actinobacteria	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
SRR25158462_k127_3355968_0	1283299.AUKG01000002_gene4594	1.118e-198	639.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4CPYZ@84995|Rubrobacteria	84995|Rubrobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DAO_C
SRR25158462_k127_3355968_18	1122939.ATUD01000015_gene989	9.106e-48	192.0	COG0778@1|root,COG0778@2|Bacteria,2HRX2@201174|Actinobacteria,4CU07@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158462_k127_3355968_11	469383.Cwoe_3798	3.757e-97	344.0	COG1657@1|root,COG4720@1|root,COG1657@2|Bacteria,COG4720@2|Bacteria,2HPSE@201174|Actinobacteria,4CR5W@84995|Rubrobacteria	84995|Rubrobacteria	I	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	-
SRR25158462_k127_3355968_22	469383.Cwoe_3799	2.552e-32	128.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158462_k127_3379865_2	1123258.AQXZ01000015_gene4757	1.626e-154	501.0	COG0477@1|root,COG0477@2|Bacteria,2GMEJ@201174|Actinobacteria,4FYE6@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	MFS_1,MFS_3,Patatin,Sugar_tr,cNMP_binding
SRR25158462_k127_3379865_15	469383.Cwoe_5683	6.619e-27	128.0	COG1309@1|root,COG1309@2|Bacteria,2HGBD@201174|Actinobacteria,4CTFM@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
SRR25158462_k127_3379865_8	472759.Nhal_1611	3.749e-97	343.0	COG1653@1|root,COG1653@2|Bacteria,1MX9J@1224|Proteobacteria,1S09S@1236|Gammaproteobacteria,1WXY8@135613|Chromatiales	135613|Chromatiales	G	extracellular solute-binding	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158462_k127_3379865_6	765912.Thimo_3432	9.956e-110	366.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,1RZC6@1236|Gammaproteobacteria,1WW50@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158462_k127_3379865_5	1380390.JIAT01000010_gene4481	3.305e-110	363.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4CPZI@84995|Rubrobacteria	84995|Rubrobacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158462_k127_3379865_3	1380390.JIAT01000010_gene4482	5.295e-151	486.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158462_k127_3379865_13	35754.JNYJ01000014_gene4857	1.623e-41	168.0	COG1309@1|root,COG1309@2|Bacteria,2IKK0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_3379865_12	314256.OG2516_13274	1.369e-65	233.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_3379865_0	469383.Cwoe_0824	1.144e-224	706.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CPN1@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158462_k127_3379865_9	1303692.SFUL_293	1.189e-96	328.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158462_k127_3379865_4	251221.35213566	8.992e-124	438.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3379865_16	926550.CLDAP_30620	3.045e-06	61.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8,TIG
SRR25158462_k127_3379865_11	469383.Cwoe_0826	1.311e-67	242.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4CQ5M@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158462_k127_3379865_1	1380390.JIAT01000009_gene1474	1.442e-207	658.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CPP3@84995|Rubrobacteria	84995|Rubrobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158462_k127_3379865_10	644548.SCNU_00860	1.644e-68	245.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4GBEI@85026|Gordoniaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158462_k127_3379865_14	1157634.KB912956_gene1937	3.445e-28	121.0	COG0645@1|root,COG0645@2|Bacteria,2I4UW@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,AAA_33,CPT
SRR25158462_k127_3379865_18	1122939.ATUD01000016_gene1823	0.0004291	51.0	COG5164@1|root,COG5164@2|Bacteria,2HCYM@201174|Actinobacteria,4CU0T@84995|Rubrobacteria	84995|Rubrobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3379865_7	469383.Cwoe_0775	5.53e-107	356.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CPZT@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
SRR25158462_k127_3386469_0	1150469.RSPPHO_03264	3.797e-21	95.0	2EBGV@1|root,335HF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3386469_3	1074889.MADAR_309	9.176e-05	48.0	2DSTI@1|root,33HD4@2|Bacteria,4NYHV@976|Bacteroidetes,1I61B@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3386469_2	1247024.JRLH01000016_gene1682	1.651e-16	82.0	2AHMX@1|root,317ZV@2|Bacteria,1PZIR@1224|Proteobacteria,1SU9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3515265_16	1283299.AUKG01000001_gene1940	2.005e-20	96.0	COG5340@1|root,COG5340@2|Bacteria,2HR3I@201174|Actinobacteria,4CSYX@84995|Rubrobacteria	84995|Rubrobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158462_k127_3515265_13	1283299.AUKG01000002_gene4665	5.057e-38	158.0	COG3428@1|root,COG3428@2|Bacteria,2HQX2@201174|Actinobacteria,4CSPP@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158462_k127_3515265_1	1283299.AUKG01000002_gene4666	7.75e-209	672.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4CPGM@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158462_k127_3515265_9	469383.Cwoe_1283	4.449e-77	267.0	COG0189@1|root,COG0189@2|Bacteria,2HI2Z@201174|Actinobacteria,4CT1T@84995|Rubrobacteria	84995|Rubrobacteria	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
SRR25158462_k127_3515265_11	1380390.JIAT01000010_gene4188	3.56e-52	203.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CQ1V@84995|Rubrobacteria	84995|Rubrobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158462_k127_3515265_7	469383.Cwoe_3725	1.605e-84	304.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CQ89@84995|Rubrobacteria	84995|Rubrobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158462_k127_3515265_8	469383.Cwoe_3722	1.229e-83	306.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4CPIX@84995|Rubrobacteria	84995|Rubrobacteria	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158462_k127_3515265_14	1122939.ATUD01000004_gene3770	2.116e-25	107.0	COG1198@1|root,COG1198@2|Bacteria,2HP74@201174|Actinobacteria,4CQJD@84995|Rubrobacteria	84995|Rubrobacteria	L	zinc-ribbons	-	-	-	-	-	-	-	-	-	-	-	-	zinc-ribbons_6
SRR25158462_k127_3515265_6	469383.Cwoe_3720	8.435e-85	291.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158462_k127_3515265_2	1380390.JIAT01000010_gene3523	1.651e-183	592.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4CRMU@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C
SRR25158462_k127_3515265_5	1380390.JIAT01000010_gene4203	1.262e-105	368.0	COG0728@1|root,COG0728@2|Bacteria,2I7WA@201174|Actinobacteria,4CPQ1@84995|Rubrobacteria	84995|Rubrobacteria	S	peptidoglycan biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3515265_3	469383.Cwoe_3710	5.445e-142	457.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4CPE1@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158462_k127_3515265_4	929712.KI912613_gene4224	1.804e-110	368.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4CQ5P@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158462_k127_3515265_10	1283299.AUKG01000002_gene4693	2.361e-58	209.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4CQB8@84995|Rubrobacteria	84995|Rubrobacteria	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158462_k127_3515265_0	469383.Cwoe_3706	1.675e-227	713.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CPH5@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158462_k127_3515265_12	1380390.JIAT01000010_gene4212	2.032e-42	162.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4CQNG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158462_k127_3515265_15	469383.Cwoe_3704	2.668e-21	103.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4CQUE@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158462_k127_3515265_17	469383.Cwoe_2561	2.062e-13	78.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_3518353_1	221288.JH992901_gene4347	2.206e-22	97.0	2DPM9@1|root,332MQ@2|Bacteria,1GAJY@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3518353_3	748671.LCRIS_01652	1.547e-13	70.0	2DPM9@1|root,332MQ@2|Bacteria,1VGFB@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3518353_5	498761.HM1_3148	2.178e-06	49.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3518353_2	498761.HM1_3148	7.569e-18	83.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3518353_4	935948.KE386495_gene1570	6.57e-11	63.0	2AEH5@1|root,314CE@2|Bacteria,1VM56@1239|Firmicutes,24XBZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3518353_0	1280001.BAOA01000033_gene2227	2.585e-24	104.0	2DMHR@1|root,32RMI@2|Bacteria,1QK1W@1224|Proteobacteria,1TI4F@1236|Gammaproteobacteria,1XYCQ@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3534710_0	469383.Cwoe_5571	1.321e-277	872.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4CPIU@84995|Rubrobacteria	84995|Rubrobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158462_k127_3534710_11	42256.RradSPS_0278	7.312e-50	188.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CT4V@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158462_k127_3534710_15	67352.JODS01000001_gene476	4.942e-23	113.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria	201174|Actinobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
SRR25158462_k127_3534710_8	469383.Cwoe_5567	1.169e-83	288.0	COG0561@1|root,COG0561@2|Bacteria,2HU8Y@201174|Actinobacteria,4CTUW@84995|Rubrobacteria	84995|Rubrobacteria	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3534710_5	1283299.AUKG01000001_gene2180	8.775e-103	339.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4CRF2@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158462_k127_3534710_14	469383.Cwoe_1520	1.228e-24	117.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158462_k127_3534710_10	469383.Cwoe_1521	1.201e-67	235.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4CQ93@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_3534710_12	929712.KI912613_gene3394	2.532e-48	189.0	COG1633@1|root,COG1633@2|Bacteria,2ICID@201174|Actinobacteria,4CTA7@84995|Rubrobacteria	84995|Rubrobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158462_k127_3534710_13	929712.KI912613_gene3395	8.88e-39	153.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin_2
SRR25158462_k127_3534710_9	266117.Rxyl_3168	4.066e-70	248.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4CPWT@84995|Rubrobacteria	84995|Rubrobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158462_k127_3534710_17	591159.ACEZ01000218_gene133	0.0001055	55.0	COG5184@1|root,COG5184@2|Bacteria,2GISE@201174|Actinobacteria	201174|Actinobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3534710_16	1380390.JIAT01000002_gene6023	7.097e-13	82.0	COG0515@1|root,COG1470@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.18	ko:K01186,ko:K20276	ko00511,ko00600,ko02024,ko04142,map00511,map00600,map02024,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_3_2,CHB_HEX_C_1,Laminin_G_3,NPCBM_assoc
SRR25158462_k127_3534710_18	746697.Aeqsu_0750	0.0004976	52.0	COG3209@1|root,COG3291@1|root,COG4935@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gal_Lectin,Gly_rich,HYR,Laminin_G_3,PKD,SprB,TSP_3
SRR25158462_k127_3534710_3	263358.VAB18032_03915	5.127e-112	372.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4DAUR@85008|Micromonosporales	201174|Actinobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158462_k127_3534710_2	1380390.JIAT01000009_gene2137	1.903e-121	400.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158462_k127_3534710_4	710111.FraQA3DRAFT_3800	1.099e-111	373.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4ES6Z@85013|Frankiales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158462_k127_3534710_7	1122939.ATUD01000011_gene2253	9.536e-84	286.0	COG0637@1|root,COG0637@2|Bacteria,2I6IT@201174|Actinobacteria,4CRIS@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158462_k127_3534710_6	43354.JOIJ01000001_gene235	1.468e-96	339.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4DZR1@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158462_k127_3534710_1	469383.Cwoe_5538	3.364e-188	597.0	COG0439@1|root,COG4770@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158462_k127_3599618_43	573370.DMR_03420	3.17e-31	123.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,42S33@68525|delta/epsilon subdivisions,2WNKG@28221|Deltaproteobacteria,2MC3F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3599618_34	1120950.KB892780_gene371	3.989e-56	213.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	todF	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158462_k127_3599618_4	469383.Cwoe_3534	7.941e-185	595.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158462_k127_3599618_17	469383.Cwoe_3533	8.783e-90	306.0	COG3705@1|root,COG3705@2|Bacteria,2I6IJ@201174|Actinobacteria,4CQ6U@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidyl-tRNA synthetase	-	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR25158462_k127_3599618_20	1283299.AUKG01000002_gene4907	2.697e-78	274.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CPQH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
SRR25158462_k127_3599618_15	469383.Cwoe_3531	2.418e-97	339.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CP7G@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158462_k127_3599618_18	1283299.AUKG01000002_gene4909	3.425e-83	280.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CPW7@84995|Rubrobacteria	84995|Rubrobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158462_k127_3599618_26	469383.Cwoe_3529	2.299e-70	251.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CQ9Q@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158462_k127_3599618_23	469383.Cwoe_3528	1.217e-72	252.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CPKT@84995|Rubrobacteria	84995|Rubrobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158462_k127_3599618_7	469383.Cwoe_3527	1.816e-115	376.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CPI7@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158462_k127_3599618_36	1122939.ATUD01000019_gene1537	2.906e-54	206.0	COG0617@1|root,COG0617@2|Bacteria,2HPJN@201174|Actinobacteria,4CQXB@84995|Rubrobacteria	84995|Rubrobacteria	J	Poly A polymerase head domain	-	-	-	-	-	-	-	-	-	-	-	-	PolyA_pol
SRR25158462_k127_3599618_35	469383.Cwoe_3524	2.13e-55	203.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CQFG@84995|Rubrobacteria	84995|Rubrobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158462_k127_3599618_25	469383.Cwoe_3523	9.365e-72	247.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CQAV@84995|Rubrobacteria	84995|Rubrobacteria	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158462_k127_3599618_31	469383.Cwoe_3522	3.667e-64	224.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158462_k127_3599618_41	1161413.HMPREF1510_1344	4.067e-32	134.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4HHXM@91061|Bacilli	91061|Bacilli	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158462_k127_3599618_51	477974.Daud_1411	1.414e-09	65.0	COG0762@1|root,COG0762@2|Bacteria,1URMB@1239|Firmicutes,24RBP@186801|Clostridia,2633K@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158462_k127_3599618_42	469383.Cwoe_3519	6.76e-32	134.0	COG0597@1|root,COG0597@2|Bacteria,2HP4E@201174|Actinobacteria,4CQFY@84995|Rubrobacteria	84995|Rubrobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158462_k127_3599618_30	1122939.ATUD01000019_gene1544	2.559e-64	227.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158462_k127_3599618_16	469383.Cwoe_3517	8.081e-97	331.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CQ0Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158462_k127_3599618_33	469383.Cwoe_3516	2.271e-57	205.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CQ46@84995|Rubrobacteria	84995|Rubrobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158462_k127_3599618_10	1380390.JIAT01000010_gene4534	2.046e-107	362.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CPH9@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158462_k127_3599618_22	469383.Cwoe_3514	2.928e-73	252.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CQ2J@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158462_k127_3599618_11	1380390.JIAT01000010_gene4536	3.154e-105	345.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158462_k127_3599618_21	469383.Cwoe_3512	1.265e-74	268.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CQ05@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158462_k127_3599618_8	1121468.AUBR01000029_gene1579	6.464e-110	368.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,42F80@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158462_k127_3599618_9	469383.Cwoe_3509	1.012e-108	363.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CPEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158462_k127_3599618_1	469383.Cwoe_3497	1.985e-210	659.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CP63@84995|Rubrobacteria	84995|Rubrobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158462_k127_3599618_37	469383.Cwoe_4819	1.902e-43	161.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005576,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158462_k127_3599618_47	469383.Cwoe_4818	6.118e-27	112.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0015643,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158462_k127_3599618_0	469383.Cwoe_3494	1.062e-232	732.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158462_k127_3599618_27	469383.Cwoe_3493	5.259e-67	237.0	COG0558@1|root,COG0558@2|Bacteria,2HGA5@201174|Actinobacteria,4CR84@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158462_k127_3599618_45	1283299.AUKG01000002_gene4958	3.249e-28	116.0	2AUU1@1|root,31KH5@2|Bacteria,2HPC3@201174|Actinobacteria,4CQQ6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3599618_28	1380390.JIAT01000010_gene4569	8.383e-67	230.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4CQ8I@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158462_k127_3599618_19	469383.Cwoe_3490	3.009e-82	285.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CPZY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158462_k127_3599618_48	469383.Cwoe_3488	7.347e-27	115.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
SRR25158462_k127_3599618_6	469383.Cwoe_5413	1.368e-158	523.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria,4CRNG@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158462_k127_3599618_46	469383.Cwoe_3484	4.891e-27	126.0	COG2050@1|root,COG2050@2|Bacteria,2HQVR@201174|Actinobacteria,4CSNV@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158462_k127_3599618_2	469383.Cwoe_3480	1.266e-185	595.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158462_k127_3599618_24	929712.KI912613_gene2917	5.137e-72	261.0	COG1629@1|root,COG4771@2|Bacteria,2IN13@201174|Actinobacteria	201174|Actinobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3599618_5	469383.Cwoe_3478	6.129e-176	567.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
SRR25158462_k127_3599618_38	1283299.AUKG01000002_gene4969	4.752e-40	157.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CQFM@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1
SRR25158462_k127_3599618_12	1283299.AUKG01000002_gene4970	7.38e-101	340.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CPGV@84995|Rubrobacteria	84995|Rubrobacteria	L	impB/mucB/samB family C-terminal domain	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
SRR25158462_k127_3599618_44	1122197.ATWI01000012_gene682	1.205e-29	126.0	COG4278@1|root,COG4278@2|Bacteria,1N6VA@1224|Proteobacteria,1SDD0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3599618_14	469383.Cwoe_1553	3.301e-99	329.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CQ2F@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158462_k127_3599618_50	485913.Krac_10833	2.683e-18	98.0	COG1289@1|root,COG1289@2|Bacteria	2|Bacteria	S	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FUSC,FUSC-like,FUSC_2
SRR25158462_k127_3599618_3	929712.KI912613_gene643	2.054e-185	623.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4CT0K@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
SRR25158462_k127_3599618_13	469383.Cwoe_5919	4.815e-100	334.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4CQ02@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_3599618_32	235985.BBPN01000008_gene4023	3.392e-61	218.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,2NJ2F@228398|Streptacidiphilus	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158462_k127_3599618_40	469383.Cwoe_5772	3.678e-35	149.0	COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria	201174|Actinobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158462_k127_3599618_49	1380390.JIAT01000009_gene1331	1.225e-20	100.0	COG4243@1|root,COG4243@2|Bacteria,2HGRK@201174|Actinobacteria,4CSQE@84995|Rubrobacteria	84995|Rubrobacteria	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158462_k127_3599618_29	469383.Cwoe_3471	4.942e-66	241.0	COG1073@1|root,COG1073@2|Bacteria,2I3YE@201174|Actinobacteria,4CRF0@84995|Rubrobacteria	84995|Rubrobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158462_k127_3599618_39	1380390.JIAT01000009_gene515	1.229e-37	147.0	COG1225@1|root,COG1225@2|Bacteria,2IJVV@201174|Actinobacteria,4CRY9@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158462_k127_3599618_53	469383.Cwoe_1036	3.075e-07	52.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,4CTD9@84995|Rubrobacteria	84995|Rubrobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158462_k127_3632906_41	1298863.AUEP01000014_gene1596	2.008e-10	74.0	28QTN@1|root,2ZD91@2|Bacteria,2ISTD@201174|Actinobacteria,4DSAS@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3632906_1	1194165.CAJF01000036_gene1677	5.352e-221	693.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4FKDW@85023|Microbacteriaceae	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158462_k127_3632906_33	469383.Cwoe_5267	8.817e-26	109.0	COG2331@1|root,COG2331@2|Bacteria,2HGE7@201174|Actinobacteria,4CQV7@84995|Rubrobacteria	84995|Rubrobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158462_k127_3632906_22	469383.Cwoe_5265	5.755e-65	237.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CPSE@84995|Rubrobacteria	84995|Rubrobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158462_k127_3632906_12	469383.Cwoe_5264	1.487e-100	337.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158462_k127_3632906_16	469383.Cwoe_5263	5.025e-78	283.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CQ57@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158462_k127_3632906_44	326427.Cagg_3577	2.625e-07	63.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3632906_2	469383.Cwoe_5259	4.664e-219	689.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CQ79@84995|Rubrobacteria	84995|Rubrobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158462_k127_3632906_13	1380390.JIAT01000016_gene5523	4.737e-99	332.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria	201174|Actinobacteria	V	abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158462_k127_3632906_21	1380390.JIAT01000016_gene5524	1.614e-65	246.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria	201174|Actinobacteria	S	Involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158462_k127_3632906_45	134676.ACPL_5056	0.0003445	50.0	COG5164@1|root,COG5164@2|Bacteria	2|Bacteria	K	cell wall organization	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Collagen,Gram_pos_anchor,Laminin_G_3
SRR25158462_k127_3632906_7	1120936.KB907211_gene83	6.197e-132	451.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4EIB7@85012|Streptosporangiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	lldA	-	1.13.12.4	ko:K00467	ko00620,map00620	-	R00319	RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158462_k127_3632906_18	929712.KI912613_gene2663	1.01e-73	267.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CPR6@84995|Rubrobacteria	84995|Rubrobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158462_k127_3632906_20	1122939.ATUD01000009_gene3005	1.878e-68	247.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158462_k127_3632906_23	469383.Cwoe_5256	1.809e-63	230.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CQ1I@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158462_k127_3632906_9	1283299.AUKG01000003_gene562	1.79e-123	419.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2GKGR@201174|Actinobacteria,4CU5U@84995|Rubrobacteria	84995|Rubrobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,SNARE_assoc
SRR25158462_k127_3632906_10	469383.Cwoe_5254	2.484e-122	405.0	COG2508@1|root,COG2508@2|Bacteria,2HJJI@201174|Actinobacteria,4CPT6@84995|Rubrobacteria	84995|Rubrobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158462_k127_3632906_35	405948.SACE_4737	1.221e-20	102.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2ICDR@201174|Actinobacteria,4E6UB@85010|Pseudonocardiales	201174|Actinobacteria	I	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR25158462_k127_3632906_34	73044.JNXP01000011_gene5561	7.297e-22	109.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRR25158462_k127_3632906_14	644283.Micau_3347	2.518e-89	315.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4DC6S@85008|Micromonosporales	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRR25158462_k127_3632906_15	1122939.ATUD01000005_gene2585	2.368e-87	312.0	2DKYI@1|root,30WMB@2|Bacteria,2I81T@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
SRR25158462_k127_3632906_31	469383.Cwoe_5837	9.091e-36	143.0	COG3247@1|root,COG3247@2|Bacteria	2|Bacteria	U	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158462_k127_3632906_4	469383.Cwoe_5251	1.588e-154	510.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CPJI@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
SRR25158462_k127_3632906_5	1283299.AUKG01000003_gene570	6.331e-146	470.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CPAI@84995|Rubrobacteria	84995|Rubrobacteria	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158462_k127_3632906_25	469383.Cwoe_5805	5.158e-54	199.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158462_k127_3632906_27	469383.Cwoe_4252	9.573e-47	182.0	arCOG08211@1|root,2ZBM3@2|Bacteria,2IDNP@201174|Actinobacteria,4CTVG@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3632906_6	469383.Cwoe_1051	1.138e-135	449.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SRR25158462_k127_3632906_26	469383.Cwoe_5243	1.31e-52	195.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CQ60@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158462_k127_3632906_19	469383.Cwoe_5242	1.944e-71	246.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CQJ6@84995|Rubrobacteria	84995|Rubrobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158462_k127_3632906_24	929712.KI912613_gene2980	3.103e-62	223.0	COG1024@1|root,COG1024@2|Bacteria,2IR3N@201174|Actinobacteria,4CPQS@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158462_k127_3632906_32	864051.BurJ1DRAFT_3700	1.342e-30	140.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
SRR25158462_k127_3632906_39	1297742.A176_05132	5.633e-16	93.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
SRR25158462_k127_3632906_0	1289387.AUKW01000001_gene4937	1.012e-235	770.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158462_k127_3632906_38	469383.Cwoe_1989	6.72e-17	94.0	COG0760@1|root,COG0760@2|Bacteria,2IRIE@201174|Actinobacteria,4CQM6@84995|Rubrobacteria	84995|Rubrobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
SRR25158462_k127_3632906_3	498761.HM1_1316	3.187e-174	556.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158462_k127_3632906_40	469383.Cwoe_5237	1.662e-10	70.0	COG2919@1|root,COG2919@2|Bacteria,2HRVE@201174|Actinobacteria,4CTYU@84995|Rubrobacteria	84995|Rubrobacteria	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158462_k127_3632906_42	179408.Osc7112_2999	1.657e-09	71.0	COG1807@1|root,COG1807@2|Bacteria,1G4VM@1117|Cyanobacteria,1H8JJ@1150|Oscillatoriales	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3632906_37	1380390.JIAT01000009_gene716	1.431e-18	91.0	2AUU5@1|root,31KH9@2|Bacteria,2HPC7@201174|Actinobacteria,4CQQB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3632906_30	469383.Cwoe_5235	1.541e-40	156.0	COG1278@1|root,COG1278@2|Bacteria,2HR26@201174|Actinobacteria,4CSWY@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SRR25158462_k127_3632906_28	1380390.JIAT01000009_gene711	1.036e-46	173.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4CQR5@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158462_k127_3632906_11	1051632.TPY_1071	8.522e-112	370.0	COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,24CYU@186801|Clostridia	186801|Clostridia	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158462_k127_3632906_29	469383.Cwoe_5229	3.466e-41	166.0	2BHC2@1|root,32BDR@2|Bacteria,2HQHF@201174|Actinobacteria,4CS2N@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158462_k127_3632906_17	469383.Cwoe_5227	1.965e-75	265.0	COG2220@1|root,COG2220@2|Bacteria,2HP2V@201174|Actinobacteria,4CQDX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158462_k127_3632906_8	469383.Cwoe_5222	1.37e-125	409.0	COG0208@1|root,COG0208@2|Bacteria,2GK48@201174|Actinobacteria,4CSBG@84995|Rubrobacteria	84995|Rubrobacteria	F	Ribonucleotide reductase, small chain	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
SRR25158462_k127_3666088_30	929712.KI912613_gene3624	2.307e-51	197.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4CSZ5@84995|Rubrobacteria	84995|Rubrobacteria	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
SRR25158462_k127_3666088_41	1089551.KE386572_gene1671	5.803e-10	68.0	COG0500@1|root,COG2226@2|Bacteria,1P9C1@1224|Proteobacteria,2U359@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158462_k127_3666088_23	469383.Cwoe_3269	9.647e-78	269.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CQ16@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158462_k127_3666088_7	469383.Cwoe_3270	9.023e-167	541.0	COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CP8D@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158462_k127_3666088_29	469383.Cwoe_3271	2.654e-53	198.0	COG2227@1|root,COG2227@2|Bacteria,2I6IG@201174|Actinobacteria,4CQTF@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158462_k127_3666088_21	469383.Cwoe_3272	1.373e-99	334.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CPRV@84995|Rubrobacteria	84995|Rubrobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158462_k127_3666088_34	1122939.ATUD01000005_gene2768	1.653e-38	166.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158462_k127_3666088_8	469383.Cwoe_3259	9.623e-163	523.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CPXQ@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158462_k127_3666088_25	485913.Krac_0576	1.721e-68	248.0	COG0451@1|root,COG0451@2|Bacteria,2G8UC@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158462_k127_3666088_17	469383.Cwoe_4192	3.477e-104	345.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CPW8@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_3666088_43	1385520.N802_11210	1.441e-07	60.0	2B97S@1|root,322IY@2|Bacteria,2H6YD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3666088_6	469383.Cwoe_3257	5.232e-188	593.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158462_k127_3666088_14	469383.Cwoe_3256	1.117e-112	370.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CQMD@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158462_k127_3666088_24	469383.Cwoe_3255	1.568e-72	252.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CQW4@84995|Rubrobacteria	84995|Rubrobacteria	J	IPP transferase	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158462_k127_3666088_3	469383.Cwoe_3249	2.518e-208	655.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158462_k127_3666088_40	316274.Haur_4905	1.51e-14	82.0	COG3241@1|root,COG3241@2|Bacteria,2G9Q8@200795|Chloroflexi,375YV@32061|Chloroflexia	32061|Chloroflexia	C	Copper binding proteins, plastocyanin/azurin family	-	GO:0008150,GO:0008152,GO:0055114	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158462_k127_3666088_10	1283299.AUKG01000002_gene5161	7.54e-159	507.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CPF2@84995|Rubrobacteria	84995|Rubrobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158462_k127_3666088_39	1122939.ATUD01000003_gene3642	5.065e-22	103.0	COG1514@1|root,COG1514@2|Bacteria,2HNKJ@201174|Actinobacteria,4CQT5@84995|Rubrobacteria	84995|Rubrobacteria	J	LigT like Phosphoesterase	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158462_k127_3666088_11	1150599.MPHLEI_12706	7.311e-148	481.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,232Q5@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158462_k127_3666088_35	469383.Cwoe_3243	2.443e-34	142.0	COG1426@1|root,COG1426@2|Bacteria,2HNYG@201174|Actinobacteria,4CQ7X@84995|Rubrobacteria	84995|Rubrobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
SRR25158462_k127_3666088_4	1380390.JIAT01000010_gene4818	1.3e-203	658.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158462_k127_3666088_19	469383.Cwoe_3240	8.674e-101	332.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CPKW@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_3666088_16	469383.Cwoe_3239	2.957e-106	364.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4CR95@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158462_k127_3666088_9	1120973.AQXL01000128_gene2793	1.19e-159	520.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,277WB@186823|Alicyclobacillaceae	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158462_k127_3666088_26	429009.Adeg_0351	7.341e-66	235.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,42FSY@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158462_k127_3666088_44	929712.KI912613_gene3570	4.807e-05	54.0	2EGQU@1|root,33AGZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158462_k127_3666088_22	469383.Cwoe_3234	4.481e-79	283.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158462_k127_3666088_12	469383.Cwoe_3233	5.389e-143	469.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158462_k127_3666088_1	1380390.JIAT01000010_gene4832	5.777e-309	962.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CPRU@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158462_k127_3666088_31	1283299.AUKG01000002_gene5181	1.569e-44	174.0	COG1651@1|root,COG1651@2|Bacteria,2HP1Q@201174|Actinobacteria,4CQC8@84995|Rubrobacteria	84995|Rubrobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
SRR25158462_k127_3666088_32	1131814.JAFO01000001_gene3699	4.775e-42	163.0	COG1225@1|root,COG1225@2|Bacteria,1RBZX@1224|Proteobacteria,2U99I@28211|Alphaproteobacteria,3EZ93@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158462_k127_3666088_36	1203602.HMPREF1527_00430	8.862e-31	123.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CW78@84998|Coriobacteriia	84998|Coriobacteriia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158462_k127_3666088_18	1283299.AUKG01000002_gene5185	3.888e-104	352.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CPIB@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158462_k127_3666088_28	929712.KI912613_gene3563	3.631e-59	226.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CPY4@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_N
SRR25158462_k127_3666088_15	1283299.AUKG01000002_gene5187	1.907e-106	359.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4CPFM@84995|Rubrobacteria	84995|Rubrobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158462_k127_3666088_38	574087.Acear_1595	3.31e-25	111.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WAT9@53433|Halanaerobiales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158462_k127_3666088_2	469383.Cwoe_3221	4.619e-247	784.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158462_k127_3666088_5	469383.Cwoe_3219	4.502e-194	625.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CPEF@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158462_k127_3666088_42	1380390.JIAT01000010_gene4843	1.31e-09	66.0	COG0779@1|root,COG0779@2|Bacteria,2HPFT@201174|Actinobacteria,4CQU9@84995|Rubrobacteria	84995|Rubrobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158462_k127_3666088_13	1380390.JIAT01000010_gene4848	1.431e-137	449.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CQAJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158462_k127_3666088_37	1283299.AUKG01000002_gene5197	3.701e-29	117.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4CQGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158462_k127_3666088_27	1380390.JIAT01000010_gene4850	3.507e-61	219.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158462_k127_3666088_33	1283299.AUKG01000002_gene5199	6.27e-40	153.0	2AU98@1|root,31JWM@2|Bacteria,2HNY8@201174|Actinobacteria,4CQ7F@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3666088_20	469383.Cwoe_3206	7.127e-100	364.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CQPU@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158462_k127_3666088_0	1380390.JIAT01000010_gene4853	0.0	1254.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CPEA@84995|Rubrobacteria	84995|Rubrobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158462_k127_3670425_4	1122619.KB892364_gene1143	1.798e-24	103.0	2EK6X@1|root,33DXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3670425_8	1410676.JNKL01000108_gene1988	2.084e-10	61.0	2DMHR@1|root,32RMI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3670425_7	1150469.RSPPHO_03248	2.777e-13	70.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2TQPI@28211|Alphaproteobacteria,2JQHV@204441|Rhodospirillales	1224|Proteobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158462_k127_3670425_2	556269.ACDQ01000020_gene815	2.299e-30	121.0	2E4EA@1|root,32Z9I@2|Bacteria,1N7HE@1224|Proteobacteria,2W66T@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3670425_9	243160.BMA1789	3.061e-08	54.0	2DRVE@1|root,33D8G@2|Bacteria,1P1ND@1224|Proteobacteria,2W3YJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3670425_5	1234679.BN424_3353	4.927e-15	74.0	2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli	91061|Bacilli	S	COG NOG38524 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3670425_3	1123309.AQYB01000012_gene113	9.349e-27	110.0	2BXJK@1|root,33AIX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_3670425_6	243230.DR_2252	2.02e-13	70.0	2ED08@1|root,33H8A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_47540_1	204773.HEAR2448	5.579e-29	116.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,474TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	'Cold-shock' DNA-binding domain	cspD2	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158462_k127_47540_2	1282356.H045_23565	7.814e-05	47.0	2EGJB@1|root,33ABH@2|Bacteria,1NI1G@1224|Proteobacteria,1RUGE@1236|Gammaproteobacteria,1YQY8@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_47540_0	1038866.KB902788_gene4586	9.827e-61	213.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2U2TB@28211|Alphaproteobacteria,3JT1W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158462_k127_593333_7	1192124.LIG30_2589	6.18e-94	314.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VHZ4@28216|Betaproteobacteria,1K1RM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRR25158462_k127_593333_0	469383.Cwoe_4165	0.0	1107.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4CPHP@84995|Rubrobacteria	84995|Rubrobacteria	H	Elongator protein 3 MiaB NifB	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158462_k127_593333_12	1283299.AUKG01000001_gene1887	5.842e-41	161.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRR25158462_k127_593333_8	1380390.JIAT01000010_gene3607	2.842e-84	289.0	COG0715@1|root,COG0715@2|Bacteria,2HPRB@201174|Actinobacteria,4CR4H@84995|Rubrobacteria	84995|Rubrobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158462_k127_593333_15	1380390.JIAT01000010_gene3606	2.784e-36	146.0	2B8EI@1|root,321PH@2|Bacteria,2HP5J@201174|Actinobacteria,4CQHJ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_593333_14	710685.MycrhN_5547	5.355e-38	162.0	COG4276@1|root,COG4276@2|Bacteria,2IIFF@201174|Actinobacteria,239IX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_593333_2	1304275.C41B8_02347	4.71e-158	517.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,1RNA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	H( )-stimulated, divalent metal cation uptake system	mntH	GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1902600	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	iSF_1195.SF2457	Nramp
SRR25158462_k127_593333_11	469383.Cwoe_4172	3.56e-43	179.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158462_k127_593333_6	469383.Cwoe_2573	5.448e-125	429.0	COG0428@1|root,COG0428@2|Bacteria,2ICIQ@201174|Actinobacteria,4CSVK@84995|Rubrobacteria	84995|Rubrobacteria	P	Mediates zinc uptake. May also transport other divalent cations	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_593333_5	1122138.AQUZ01000001_gene1866	2.324e-143	467.0	COG2132@1|root,COG2132@2|Bacteria,2GPUP@201174|Actinobacteria,4DT49@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158462_k127_593333_9	469383.Cwoe_4173	3.729e-76	271.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158462_k127_593333_18	1380390.JIAT01000010_gene3600	7.821e-05	51.0	2A2E0@1|root,30QR0@2|Bacteria,2HRC5@201174|Actinobacteria,4CT9M@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_593333_10	1317118.ATO8_19704	2.5e-69	250.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,4KN4G@93682|Roseivivax	28211|Alphaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158462_k127_593333_1	469383.Cwoe_4182	2.059e-214	671.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CRE2@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158462_k127_593333_17	1380390.JIAT01000010_gene3594	7.314e-08	65.0	2AWN7@1|root,31NIY@2|Bacteria,2HR42@201174|Actinobacteria,4CSZD@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_593333_16	1380390.JIAT01000010_gene4370	1.838e-10	75.0	COG1409@1|root,COG1409@2|Bacteria,2GVVJ@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR25158462_k127_593333_4	1380390.JIAT01000014_gene6288	1.49e-155	524.0	COG0028@1|root,COG0515@1|root,COG1470@1|root,COG2133@1|root,COG3291@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1470@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
SRR25158462_k127_593333_13	469383.Cwoe_4191	2.137e-39	149.0	COG2127@1|root,COG2127@2|Bacteria,2HPG0@201174|Actinobacteria,4CQUJ@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158462_k127_593333_3	1380390.JIAT01000010_gene3587	7.226e-158	503.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4CPAH@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158462_k127_604898_3	617140.AJZE01000061_gene2940	2.595e-13	70.0	2AWRM@1|root,31NNJ@2|Bacteria,1QKD5@1224|Proteobacteria,1TIGU@1236|Gammaproteobacteria,1XZ3R@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_604898_1	1123399.AQVE01000006_gene3409	1.988e-24	103.0	28U04@1|root,2ZG6H@2|Bacteria,1P4EV@1224|Proteobacteria,1STQS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_604898_0	1115515.EV102420_46_00003	1.565e-28	114.0	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,1S8U2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_63	266117.Rxyl_1569	9.248e-14	80.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4CPI8@84995|Rubrobacteria	84995|Rubrobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158462_k127_651040_20	1122604.JONR01000007_gene2832	1.067e-89	303.0	COG0491@1|root,COG0491@2|Bacteria,1N1ZW@1224|Proteobacteria,1RNRE@1236|Gammaproteobacteria,1X4Z9@135614|Xanthomonadales	135614|Xanthomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158462_k127_651040_62	1380390.JIAT01000010_gene4090	2.193e-15	84.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_651040_51	469383.Cwoe_3656	1.01e-32	138.0	COG0500@1|root,COG2226@2|Bacteria,2IREW@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158462_k127_651040_65	1184607.AUCHE_01_00590	1.501e-08	58.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4F6MY@85018|Dermatophilaceae	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
SRR25158462_k127_651040_45	1380390.JIAT01000010_gene4864	6.269e-49	187.0	2DM23@1|root,31DUR@2|Bacteria,2GIYZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF2204,NTP_transf_5
SRR25158462_k127_651040_22	1380390.JIAT01000010_gene4865	2.416e-86	292.0	COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria	201174|Actinobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158462_k127_651040_36	1380390.JIAT01000010_gene4522	4.806e-65	238.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
SRR25158462_k127_651040_56	1183438.GKIL_2486	1.881e-20	99.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_35	1961.JOAK01000003_gene1527	1.179e-65	251.0	COG4257@1|root,COG4257@2|Bacteria,2GJU3@201174|Actinobacteria	201174|Actinobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF11
SRR25158462_k127_651040_66	1283299.AUKG01000002_gene3893	2.835e-08	67.0	COG2885@1|root,COG4733@1|root,COG2885@2|Bacteria,COG4733@2|Bacteria,2HENQ@201174|Actinobacteria,4CQR9@84995|Rubrobacteria	84995|Rubrobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40
SRR25158462_k127_651040_48	469383.Cwoe_5392	1.702e-39	169.0	COG4447@1|root,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_1	405948.SACE_7076	8.61e-210	666.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4E11F@85010|Pseudonocardiales	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158462_k127_651040_0	1038869.AXAN01000009_gene4705	2.13e-217	687.0	COG0492@1|root,COG0492@2|Bacteria,1MVX2@1224|Proteobacteria,2VM3V@28216|Betaproteobacteria,1K4AE@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158462_k127_651040_38	1122939.ATUD01000008_gene2489	1.445e-60	215.0	COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CQSM@84995|Rubrobacteria	84995|Rubrobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
SRR25158462_k127_651040_42	469383.Cwoe_5869	6.773e-55	206.0	COG3662@1|root,COG3662@2|Bacteria,2II6C@201174|Actinobacteria,4CREG@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158462_k127_651040_61	469383.Cwoe_4695	1.891e-15	80.0	2A6PH@1|root,30VHE@2|Bacteria,2HRXZ@201174|Actinobacteria,4CU19@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_34	1048339.KB913029_gene4924	2.686e-66	243.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4ESG4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158462_k127_651040_67	65093.PCC7418_1179	3.47e-08	58.0	COG3620@1|root,COG3620@2|Bacteria,1G9PF@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_651040_46	1380390.JIAT01000012_gene3188	1.599e-40	170.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,2HRFM@201174|Actinobacteria,4CTEG@84995|Rubrobacteria	84995|Rubrobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,PKD
SRR25158462_k127_651040_16	469383.Cwoe_3098	4.039e-107	356.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria,4CPH4@84995|Rubrobacteria	84995|Rubrobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158462_k127_651040_14	469383.Cwoe_3099	7.869e-110	362.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4CQD5@84995|Rubrobacteria	84995|Rubrobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158462_k127_651040_17	469383.Cwoe_3100	1.295e-103	355.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CRC6@84995|Rubrobacteria	84995|Rubrobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158462_k127_651040_33	469383.Cwoe_1004	7.7e-67	251.0	COG0018@1|root,COG0018@2|Bacteria	2|Bacteria	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158462_k127_651040_3	680198.SCAB_8401	4.139e-202	659.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,2GKJT@201174|Actinobacteria	201174|Actinobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
SRR25158462_k127_651040_60	272123.Anacy_3718	9.893e-17	95.0	COG0115@1|root,COG1247@1|root,COG0115@2|Bacteria,COG1247@2|Bacteria,1G1GM@1117|Cyanobacteria,1HT7W@1161|Nostocales	1117|Cyanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158462_k127_651040_41	272123.Anacy_3717	6.492e-55	209.0	COG0123@1|root,COG0123@2|Bacteria	2|Bacteria	BQ	including yeast histone deacetylase and acetoin utilization protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
SRR25158462_k127_651040_57	1961.JOAK01000007_gene4213	2.933e-18	98.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	-	-	4.2.99.21,5.4.99.5	ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	M00024,M00025	R01715,R06602	RC01549,RC02148,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
SRR25158462_k127_651040_13	1068980.ARVW01000001_gene1524	1.078e-112	386.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,4E0VF@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158462_k127_651040_31	1206725.BAFU01000019_gene3561	7.679e-68	248.0	COG3486@1|root,COG3486@2|Bacteria,2I991@201174|Actinobacteria,4FXSI@85025|Nocardiaceae	201174|Actinobacteria	Q	L-lysine 6-monooxygenase (NADPH-requiring)	nbtG	-	-	ko:K04793	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	K_oxygenase
SRR25158462_k127_651040_8	1137271.AZUM01000002_gene2524	2.252e-132	439.0	COG4993@1|root,COG4993@2|Bacteria,2I3R4@201174|Actinobacteria,4EF6T@85010|Pseudonocardiales	201174|Actinobacteria	G	PQQ-like domain	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
SRR25158462_k127_651040_43	287986.DV20_04860	7.485e-55	197.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria,4E45T@85010|Pseudonocardiales	201174|Actinobacteria	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158462_k127_651040_71	1440774.Y900_012100	1.496e-06	60.0	COG1714@1|root,COG1714@2|Bacteria,2IN6K@201174|Actinobacteria,239Y0@1762|Mycobacteriaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158462_k127_651040_40	469383.Cwoe_0875	6.617e-56	207.0	COG1808@1|root,COG1808@2|Bacteria,2GJQ4@201174|Actinobacteria,4CSRH@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158462_k127_651040_49	1380390.JIAT01000010_gene3610	6.128e-35	153.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CRAQ@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158462_k127_651040_32	469383.Cwoe_5027	3.182e-67	246.0	COG3511@1|root,COG3511@2|Bacteria,2IC2P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
SRR25158462_k127_651040_12	469383.Cwoe_5023	5.01e-118	403.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158462_k127_651040_15	469383.Cwoe_5022	1.216e-107	370.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria	2|Bacteria	P	phosphate transport system permease	pstA	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158462_k127_651040_9	469383.Cwoe_5021	2.322e-132	429.0	COG0573@1|root,COG0573@2|Bacteria,2ISS5@201174|Actinobacteria,4CPV6@84995|Rubrobacteria	84995|Rubrobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158462_k127_651040_30	469383.Cwoe_5020	3.046e-68	241.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SRR25158462_k127_651040_21	1206732.BAGD01000081_gene3349	6.834e-87	299.0	29QHM@1|root,30BH3@2|Bacteria,2HJ8G@201174|Actinobacteria,4G5TC@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_11	469383.Cwoe_4911	4.655e-124	408.0	COG1118@1|root,COG1118@2|Bacteria,2I3KJ@201174|Actinobacteria,4CPG0@84995|Rubrobacteria	84995|Rubrobacteria	P	TOBE-like domain	-	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE,TOBE_3
SRR25158462_k127_651040_24	1048339.KB913029_gene3981	3.358e-84	287.0	COG4208@1|root,COG4208@2|Bacteria,2GMTK@201174|Actinobacteria,4EV7G@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158462_k127_651040_23	1380390.JIAT01000009_gene1161	6.629e-85	291.0	COG0555@1|root,COG0555@2|Bacteria,2GP6P@201174|Actinobacteria,4CSDJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158462_k127_651040_18	929712.KI912613_gene3363	5.445e-95	322.0	COG1613@1|root,COG1613@2|Bacteria,2GJIK@201174|Actinobacteria,4CRE5@84995|Rubrobacteria	84995|Rubrobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SRR25158462_k127_651040_10	469383.Cwoe_0102	5.241e-126	409.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4CU6B@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158462_k127_651040_25	469383.Cwoe_1838	5.327e-82	285.0	COG0420@1|root,COG0420@2|Bacteria,2HPX3@201174|Actinobacteria,4CRBR@84995|Rubrobacteria	84995|Rubrobacteria	L	3'-5' exonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158462_k127_651040_19	208444.JNYY01000006_gene7031	3.579e-92	327.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria,4EDXN@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,FSH1,Hydrolase_4
SRR25158462_k127_651040_69	1380370.JIBA01000012_gene3416	6.976e-08	58.0	COG1695@1|root,COG1695@2|Bacteria,2IQ8I@201174|Actinobacteria,4FHXQ@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158462_k127_651040_68	1121468.AUBR01000025_gene2985	4.345e-08	61.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24RT7@186801|Clostridia,42HF6@68295|Thermoanaerobacterales	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
SRR25158462_k127_651040_70	1411123.JQNH01000001_gene855	1.277e-06	56.0	COG1708@1|root,COG1708@2|Bacteria,1PXTE@1224|Proteobacteria,2UKXP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158462_k127_651040_29	163908.KB235896_gene2964	1.335e-70	260.0	COG3593@1|root,COG3593@2|Bacteria,1GBS7@1117|Cyanobacteria	1117|Cyanobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_5	266117.Rxyl_2349	4.148e-183	582.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	atsG	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158462_k127_651040_50	1122939.ATUD01000008_gene2498	1.273e-33	141.0	COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria,4CPQR@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_651040_27	469383.Cwoe_4579	3.693e-76	265.0	COG1994@1|root,COG1994@2|Bacteria,2H6BD@201174|Actinobacteria,4CS7E@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_37	1380390.JIAT01000010_gene4511	1.316e-62	232.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4CR60@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_651040_2	1068978.AMETH_6088	3.02e-203	647.0	2CB1C@1|root,2Z7M2@2|Bacteria,2GM87@201174|Actinobacteria	201174|Actinobacteria	S	Transmembrane protein of unknown function (DUF3556)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3556
SRR25158462_k127_651040_4	1068978.AMETH_6089	1.725e-194	618.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4E059@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phytoene dehydrogenase-like oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158462_k127_651040_26	1380390.JIAT01000012_gene3007	6.567e-82	287.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4CPQ2@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158462_k127_651040_28	1283299.AUKG01000001_gene2799	2.613e-71	269.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4CR8D@84995|Rubrobacteria	84995|Rubrobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158462_k127_651040_53	1380390.JIAT01000010_gene4844	4.851e-26	113.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria,4CSUA@84995|Rubrobacteria	84995|Rubrobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_74	469383.Cwoe_0478	0.0003189	51.0	COG5164@1|root,COG5164@2|Bacteria,2HCYM@201174|Actinobacteria,4CU0T@84995|Rubrobacteria	84995|Rubrobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_44	521011.Mpal_1345	4.645e-52	214.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158462_k127_651040_58	1380390.JIAT01000010_gene4090	2.784e-17	89.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRRJ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_651040_55	1283299.AUKG01000003_gene331	1.455e-22	104.0	COG0640@1|root,COG0640@2|Bacteria,2IIJ9@201174|Actinobacteria,4CRHR@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_651040_7	700508.D174_16205	2.793e-142	467.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,236QK@1762|Mycobacteriaceae	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRR25158462_k127_651040_73	1283299.AUKG01000002_gene4570	5.286e-05	53.0	2AVX1@1|root,31X3Y@2|Bacteria,2HYM4@201174|Actinobacteria,4CQWW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_651040_39	1380390.JIAT01000010_gene4104	7.896e-59	215.0	28RTZ@1|root,2ZE6B@2|Bacteria,2HQNJ@201174|Actinobacteria,4CS8Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
SRR25158462_k127_651040_47	469383.Cwoe_3800	7.22e-40	160.0	COG0619@1|root,COG0619@2|Bacteria,2IIUE@201174|Actinobacteria,4CRAP@84995|Rubrobacteria	84995|Rubrobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158462_k127_651040_6	469383.Cwoe_3799	1.409e-151	493.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158462_k127_691314_4	562970.Btus_1793	1.015e-115	380.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,2785F@186823|Alicyclobacillaceae	91061|Bacilli	E	Glutamate synthase central domain	gltA2	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158462_k127_691314_3	1122223.KB890699_gene549	3.32e-132	436.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1WIA7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158462_k127_691314_10	269797.Mbar_A3620	1.92e-66	238.0	COG3291@1|root,COG3391@1|root,arCOG03991@1|root,arCOG02510@2157|Archaea,arCOG03563@2157|Archaea,arCOG03991@2157|Archaea,2Y2RX@28890|Euryarchaeota,2NAHT@224756|Methanomicrobia	224756|Methanomicrobia	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PKD
SRR25158462_k127_691314_15	469383.Cwoe_1797	7.92e-35	140.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451,FHA,Yop-YscD_cpl
SRR25158462_k127_691314_17	1283299.AUKG01000001_gene3079	1.272e-30	135.0	29VB2@1|root,30GR7@2|Bacteria,2HY8H@201174|Actinobacteria,4CQFR@84995|Rubrobacteria	84995|Rubrobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158462_k127_691314_21	1283299.AUKG01000001_gene3080	2.561e-12	78.0	2AUMD@1|root,31KA7@2|Bacteria,2HP75@201174|Actinobacteria,4CQJE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_691314_5	469383.Cwoe_1801	5.803e-115	392.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,4CRTA@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158462_k127_691314_6	469383.Cwoe_1802	4.306e-110	368.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4CP5Z@84995|Rubrobacteria	84995|Rubrobacteria	O	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158462_k127_691314_16	929712.KI912613_gene3062	1.201e-30	124.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4CQQK@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158462_k127_691314_2	1380390.JIAT01000014_gene6239	6.117e-143	466.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CQIM@84995|Rubrobacteria	84995|Rubrobacteria	L	Exonuclease VII, large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158462_k127_691314_18	1380390.JIAT01000014_gene6240	1.601e-22	100.0	COG1722@1|root,COG1722@2|Bacteria,2HRH7@201174|Actinobacteria,4CTGW@84995|Rubrobacteria	84995|Rubrobacteria	L	Exonuclease VII small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Exonuc_VII_S
SRR25158462_k127_691314_1	469383.Cwoe_1805	5.315e-169	580.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria,4CPD7@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158462_k127_691314_7	469383.Cwoe_1804	1.67e-106	382.0	COG3857@1|root,COG3857@2|Bacteria,2HNUC@201174|Actinobacteria,4CQ2I@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
SRR25158462_k127_691314_9	1283299.AUKG01000001_gene3121	1.974e-68	235.0	2AW45@1|root,31MZ2@2|Bacteria,2HNU6@201174|Actinobacteria,4CQ2D@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_691314_0	469383.Cwoe_4949	4.191e-217	683.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CSAZ@84995|Rubrobacteria	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158462_k127_691314_11	469383.Cwoe_1828	4.256e-64	228.0	COG1011@1|root,COG1011@2|Bacteria,2HP8B@201174|Actinobacteria,4CTW5@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158462_k127_691314_20	469383.Cwoe_1829	1.09e-14	79.0	2AZ12@1|root,31R76@2|Bacteria,2HPZ2@201174|Actinobacteria,4CREC@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_691314_12	469383.Cwoe_0750	7.96e-60	212.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,4CSRS@84995|Rubrobacteria	84995|Rubrobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158462_k127_691314_13	469383.Cwoe_1832	1.372e-38	147.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CQHE@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158462_k127_691314_19	326424.FRAAL5040	6.32e-15	83.0	COG1670@1|root,COG1670@2|Bacteria,2GR79@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158462_k127_691314_14	1380390.JIAT01000014_gene6150	4.662e-38	148.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4CU3T@84995|Rubrobacteria	84995|Rubrobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	FxsA
SRR25158462_k127_691314_8	469383.Cwoe_1036	7.636e-102	338.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GJ3V@201174|Actinobacteria,4CTD9@84995|Rubrobacteria	84995|Rubrobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
SRR25158462_k127_695662_1	469383.Cwoe_3753	2.197e-166	528.0	COG1003@1|root,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4CPH8@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
SRR25158462_k127_695662_9	404589.Anae109_1007	1.13e-107	356.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158462_k127_695662_11	1009370.ALO_10424	1.464e-71	252.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4H2SP@909932|Negativicutes	909932|Negativicutes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158462_k127_695662_17	1089548.KI783301_gene75	4.142e-44	169.0	COG1117@1|root,COG1117@2|Bacteria,1V2UH@1239|Firmicutes,4HDCU@91061|Bacilli,3WFJ4@539002|Bacillales incertae sedis	91061|Bacilli	P	ATPases associated with a variety of cellular activities	yjkB	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
SRR25158462_k127_695662_15	1183438.GKIL_2541	3.02e-48	190.0	COG0390@1|root,COG0390@2|Bacteria,1G1TY@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0014)	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158462_k127_695662_16	469383.Cwoe_0762	5.029e-46	172.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158462_k127_695662_21	1380390.JIAT01000009_gene2098	1.315e-31	141.0	COG2866@1|root,COG2866@2|Bacteria,2HPMB@201174|Actinobacteria,4CQZA@84995|Rubrobacteria	84995|Rubrobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158462_k127_695662_3	469383.Cwoe_0976	9.248e-154	505.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CPQ3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_695662_5	469383.Cwoe_3749	1.825e-140	452.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CPN5@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158462_k127_695662_12	469383.Cwoe_3747	1.787e-63	240.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4CQNN@84995|Rubrobacteria	84995|Rubrobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158462_k127_695662_13	1380390.JIAT01000010_gene4166	1.124e-62	220.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4CPY7@84995|Rubrobacteria	84995|Rubrobacteria	K	Segregation and condensation complex subunit ScpB	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158462_k127_695662_10	469383.Cwoe_3744	1.067e-74	259.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CQ72@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158462_k127_695662_19	1380390.JIAT01000010_gene3564	2.439e-39	163.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158462_k127_695662_18	1380390.JIAT01000010_gene4172	4.584e-44	166.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,4CQE6@84995|Rubrobacteria	84995|Rubrobacteria	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158462_k127_695662_8	1283299.AUKG01000002_gene4647	1.1e-110	379.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,4CPIS@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158462_k127_695662_4	469383.Cwoe_4999	1.548e-147	479.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CSEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158462_k127_695662_7	469383.Cwoe_3737	3.861e-114	380.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158462_k127_695662_6	469383.Cwoe_3736	1.798e-137	450.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CPPD@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158462_k127_695662_23	63737.Npun_R6261	0.0001021	54.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
SRR25158462_k127_695662_14	1122939.ATUD01000004_gene3757	2.609e-48	187.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CQCH@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158462_k127_695662_2	1283299.AUKG01000002_gene4652	3.194e-157	507.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CPBT@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158462_k127_695662_0	469383.Cwoe_3729	1.024e-186	592.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CPIK@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158462_k127_695662_22	469383.Cwoe_2517	2.202e-30	128.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_9	469383.Cwoe_3572	3.561e-107	356.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_696403_26	1283299.AUKG01000001_gene2448	1.034e-60	216.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CQIK@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158462_k127_696403_8	469383.Cwoe_5367	4.305e-127	414.0	COG1469@1|root,COG1469@2|Bacteria,2IBX9@201174|Actinobacteria	201174|Actinobacteria	S	Type I GTP cyclohydrolase folE2	-	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
SRR25158462_k127_696403_5	469383.Cwoe_5366	3.501e-162	519.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CPPG@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158462_k127_696403_42	685727.REQ_07220	2.815e-27	123.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,4G0XD@85025|Nocardiaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158462_k127_696403_47	570268.ANBB01000060_gene771	1.005e-20	103.0	COG3631@1|root,COG3631@2|Bacteria,2IHRM@201174|Actinobacteria,4EPPX@85012|Streptosporangiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158462_k127_696403_56	1150864.MILUP08_41899	2.419e-05	57.0	2F90D@1|root,341C4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_28	1449353.JQMQ01000005_gene1069	4.244e-58	210.0	COG4221@1|root,COG4221@2|Bacteria,2I2Z8@201174|Actinobacteria,2NF2P@228398|Streptacidiphilus	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158462_k127_696403_19	1380390.JIAT01000009_gene571	3.004e-72	263.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4CRRD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158462_k127_696403_58	1415166.NONO_c10070	0.0006834	52.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158462_k127_696403_10	1380390.JIAT01000014_gene6267	1.046e-103	347.0	COG2132@1|root,COG2132@2|Bacteria,2HQUD@201174|Actinobacteria,4CSKX@84995|Rubrobacteria	84995|Rubrobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
SRR25158462_k127_696403_53	1206735.BAGG01000019_gene974	3.7e-06	59.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158462_k127_696403_33	1380390.JIAT01000014_gene6266	4.316e-52	204.0	COG4677@1|root,COG4677@2|Bacteria,2HQKH@201174|Actinobacteria,4CS61@84995|Rubrobacteria	84995|Rubrobacteria	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_23	1283299.AUKG01000002_gene5280	3.865e-66	239.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria,4CRC2@84995|Rubrobacteria	84995|Rubrobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_52	307480.IW16_18430	6.938e-07	56.0	COG4319@1|root,COG4319@2|Bacteria,4PG97@976|Bacteroidetes,1IH4F@117743|Flavobacteriia,3ZT10@59732|Chryseobacterium	976|Bacteroidetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158462_k127_696403_59	935837.JAEK01000042_gene3832	0.000703	42.0	2DIA4@1|root,302HW@2|Bacteria,1U5Y3@1239|Firmicutes,4IM9X@91061|Bacilli,1ZJJZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_15	1121924.ATWH01000002_gene3731	1.594e-83	289.0	28HY4@1|root,2Z83J@2|Bacteria,2GWQV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_27	1246995.AFR_01500	2.129e-60	235.0	COG0207@1|root,COG1409@1|root,COG0207@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	yjjH	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Metallophos,Thymidylat_synt
SRR25158462_k127_696403_49	467200.ACFA01000003_gene1685	9.057e-15	82.0	COG0500@1|root,COG2226@2|Bacteria,2IDSB@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158462_k127_696403_6	446462.Amir_4368	7.365e-152	489.0	COG1960@1|root,COG1960@2|Bacteria,2I5JQ@201174|Actinobacteria,4E1PG@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158462_k127_696403_21	479435.Kfla_0942	3.884e-70	244.0	2DF2G@1|root,2ZQ7S@2|Bacteria,2I868@201174|Actinobacteria,4DWJ8@85009|Propionibacteriales	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158462_k127_696403_35	118173.KB235910_gene4949	1.336e-40	158.0	28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria,1HEPR@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_51	1173020.Cha6605_2547	9.53e-09	60.0	2CX21@1|root,32T0Y@2|Bacteria,1G8F6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_13	469383.Cwoe_0829	7.954e-90	312.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRAY@84995|Rubrobacteria	201174|Actinobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158462_k127_696403_45	469383.Cwoe_1320	9.534e-25	104.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CQU8@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158462_k127_696403_54	929712.KI912613_gene4963	4.45e-06	56.0	COG0690@1|root,COG0690@2|Bacteria,2HQ1F@201174|Actinobacteria,4CRHK@84995|Rubrobacteria	84995|Rubrobacteria	U	SecE/Sec61-gamma subunits of protein translocation complex	-	-	-	-	-	-	-	-	-	-	-	-	SecE
SRR25158462_k127_696403_14	469383.Cwoe_1322	9.289e-84	282.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CQ4I@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158462_k127_696403_25	1122939.ATUD01000003_gene3552	1.848e-63	220.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4CQ3Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158462_k127_696403_12	469383.Cwoe_1324	2.705e-94	318.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CPV5@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158462_k127_696403_29	469383.Cwoe_1325	9.99e-55	200.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CQ0J@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158462_k127_696403_34	469383.Cwoe_1326	7.111e-49	177.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4CQ9X@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158462_k127_696403_1	1380390.JIAT01000011_gene2565	0.0	1857.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158462_k127_696403_0	469383.Cwoe_1328	0.0	2005.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CP97@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158462_k127_696403_55	1122609.AUGT01000019_gene273	2.102e-05	54.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K19233,ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40,1.B.40.2	-	-	Collagen,ESPR,Haemagg_act,YadA_anchor,YadA_head,YadA_stalk
SRR25158462_k127_696403_4	1122939.ATUD01000001_gene642	2.214e-186	594.0	COG2072@1|root,COG2072@2|Bacteria,2GMDH@201174|Actinobacteria,4CS42@84995|Rubrobacteria	84995|Rubrobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
SRR25158462_k127_696403_57	1283299.AUKG01000003_gene209	0.0002259	52.0	2B73N@1|root,3204N@2|Bacteria,2HRH2@201174|Actinobacteria,4CTGQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_38	469383.Cwoe_1330	4.728e-38	156.0	29XHR@1|root,30J8F@2|Bacteria,2HU87@201174|Actinobacteria,4CTU4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_696403_20	469383.Cwoe_1336	3.521e-70	249.0	COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CQ77@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158462_k127_696403_24	469383.Cwoe_1335	3.024e-64	226.0	COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4CQ35@84995|Rubrobacteria	84995|Rubrobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158462_k127_696403_2	1380390.JIAT01000011_gene2585	0.0	1009.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CPGY@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158462_k127_696403_3	471223.GWCH70_0109	8.936e-203	638.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,1WF15@129337|Geobacillus	91061|Bacilli	J	GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	iSB619.SA_RS02960	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158462_k127_696403_31	469383.Cwoe_1339	6.626e-53	188.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4CQFD@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158462_k127_696403_17	1283299.AUKG01000001_gene2631	1.308e-81	294.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CPFD@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158462_k127_696403_32	469383.Cwoe_1341	1.565e-52	192.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CPXR@84995|Rubrobacteria	84995|Rubrobacteria	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158462_k127_696403_40	1283299.AUKG01000001_gene2633	2.302e-30	131.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4CQIU@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158462_k127_696403_7	469383.Cwoe_1343	3.889e-128	416.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CPEQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158462_k127_696403_36	1283299.AUKG01000001_gene2635	1.654e-38	153.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CQEC@84995|Rubrobacteria	84995|Rubrobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158462_k127_696403_39	1380390.JIAT01000011_gene2593	6.505e-38	149.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4CQP9@84995|Rubrobacteria	84995|Rubrobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158462_k127_696403_11	469383.Cwoe_1346	1.161e-102	349.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CPWK@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158462_k127_696403_22	986075.CathTA2_2526	1.762e-69	239.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli	91061|Bacilli	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158462_k127_696403_50	1123320.KB889574_gene5566	8.063e-11	70.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158462_k127_696403_41	469383.Cwoe_1349	1.942e-28	124.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CQJP@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158462_k127_696403_30	469383.Cwoe_1350	5.753e-54	203.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CQ56@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158462_k127_696403_43	469383.Cwoe_1351	7.13e-27	119.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4CQNC@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158462_k127_696403_18	469383.Cwoe_1352	3.904e-78	275.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158462_k127_696403_44	469383.Cwoe_1353	1.887e-25	108.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CQKA@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158462_k127_696403_37	1203568.HMPREF1484_01131	2.478e-38	147.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4FCPV@85020|Dermabacteraceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158462_k127_696403_16	1380390.JIAT01000011_gene2603	1.149e-81	275.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158462_k127_696403_48	1283299.AUKG01000001_gene2647	6.8e-19	95.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4CQBN@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158462_k127_753150_12	469383.Cwoe_5554	1.919e-39	148.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4CR2R@84995|Rubrobacteria	84995|Rubrobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158462_k127_753150_3	700508.D174_04100	3.508e-121	397.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,235PP@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158462_k127_753150_6	469383.Cwoe_2174	2.256e-110	383.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CPQJ@84995|Rubrobacteria	84995|Rubrobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158462_k127_753150_1	1209984.BN978_03763	7.374e-128	419.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,236AR@1762|Mycobacteriaceae	201174|Actinobacteria	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158462_k127_753150_4	710686.Mycsm_00298	5.105e-119	392.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,23421@1762|Mycobacteriaceae	201174|Actinobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158462_k127_753150_0	258533.BN977_04029	3.788e-176	568.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,2370B@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158462_k127_753150_9	1380390.JIAT01000011_gene2652	2.637e-91	316.0	COG0477@1|root,COG2814@2|Bacteria,2ID9K@201174|Actinobacteria,4CQJG@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_753150_5	1380390.JIAT01000011_gene2651	3.21e-114	387.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4CR7M@84995|Rubrobacteria	84995|Rubrobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158462_k127_753150_8	751945.Theos_1539	1.693e-94	320.0	COG1063@1|root,COG1063@2|Bacteria,1WJNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158462_k127_753150_15	469383.Cwoe_0707	2.664e-24	111.0	COG1725@1|root,COG1725@2|Bacteria	469383.Cwoe_0707|-	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_753150_7	929712.KI912613_gene4841	3.351e-98	332.0	COG0767@1|root,COG0767@2|Bacteria,2IAUN@201174|Actinobacteria,4CR2S@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158462_k127_753150_2	1380390.JIAT01000011_gene2768	2.285e-121	400.0	COG0767@1|root,COG0767@2|Bacteria,2GJ27@201174|Actinobacteria,4CPTC@84995|Rubrobacteria	84995|Rubrobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SRR25158462_k127_753150_11	626887.J057_17015	1.296e-40	160.0	COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,1SFXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
SRR25158462_k127_753150_18	195253.Syn6312_1203	5.414e-22	102.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1H11A@1129|Synechococcus	1117|Cyanobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158462_k127_753150_17	469383.Cwoe_1077	1.641e-22	101.0	2AUHF@1|root,31K5S@2|Bacteria,2HP4J@201174|Actinobacteria,4CQG4@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_753150_14	1380390.JIAT01000009_gene510	1.131e-33	134.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4CQHQ@84995|Rubrobacteria	84995|Rubrobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158462_k127_753150_13	1440053.JOEI01000011_gene4756	5.402e-36	151.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_753150_10	469383.Cwoe_3231	1.526e-53	194.0	COG4276@1|root,COG4276@2|Bacteria,2HP31@201174|Actinobacteria,4CQE3@84995|Rubrobacteria	84995|Rubrobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158462_k127_753150_16	1150474.JQJI01000039_gene1928	1.164e-22	107.0	COG0745@1|root,COG0745@2|Bacteria,2GCXG@200918|Thermotogae	200918|Thermotogae	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158462_k127_822783_9	469383.Cwoe_3080	4.611e-83	284.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CQ7R@84995|Rubrobacteria	84995|Rubrobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158462_k127_822783_12	469383.Cwoe_3081	2.279e-78	282.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CPFG@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158462_k127_822783_1	1380390.JIAT01000009_gene2065	2.538e-176	566.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRC3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_822783_2	469383.Cwoe_3082	6.387e-154	507.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CPSV@84995|Rubrobacteria	84995|Rubrobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158462_k127_822783_3	469383.Cwoe_3083	6.097e-131	428.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4CQX8@84995|Rubrobacteria	84995|Rubrobacteria	S	Thiamin pyrophosphokinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR25158462_k127_822783_13	1121428.DESHY_60111___1	3.745e-19	98.0	28JWD@1|root,2Z9M5@2|Bacteria,1UZF1@1239|Firmicutes,24HZN@186801|Clostridia,261TF@186807|Peptococcaceae	186801|Clostridia	S	Copper transport outer membrane protein, MctB	-	-	-	-	-	-	-	-	-	-	-	-	MctB
SRR25158462_k127_822783_11	469383.Cwoe_3085	1.377e-80	276.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4CTZJ@84995|Rubrobacteria	84995|Rubrobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_822783_0	469383.Cwoe_3086	2.508e-253	809.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CPN2@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158462_k127_822783_7	469383.Cwoe_3087	3.61e-101	347.0	COG2195@1|root,COG2195@2|Bacteria,2HPTW@201174|Actinobacteria,4CR7V@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158462_k127_822783_6	469383.Cwoe_3088	1.077e-103	363.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria,4CTCT@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158462_k127_822783_4	469383.Cwoe_3090	7.306e-126	417.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CQMQ@84995|Rubrobacteria	84995|Rubrobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158462_k127_822783_10	1380390.JIAT01000003_gene5461	1.049e-80	278.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CPMX@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158462_k127_822783_8	1380390.JIAT01000003_gene5463	2.711e-89	301.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CQNS@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158462_k127_822783_5	1380390.JIAT01000007_gene5189	9.163e-111	371.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CPM8@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158462_k127_844092_6	1283299.AUKG01000003_gene610	4.629e-159	507.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CRM8@84995|Rubrobacteria	84995|Rubrobacteria	EH	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158462_k127_844092_18	469383.Cwoe_5209	3.737e-89	303.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CPJE@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158462_k127_844092_64	644107.SL1157_0518	3.815e-06	50.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_40	1385520.N802_11570	8.931e-40	162.0	2F3Z3@1|root,33WR0@2|Bacteria,2IG4D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_63	1206101.AZXC01000016_gene3424	2.782e-07	59.0	2BK16@1|root,32EED@2|Bacteria,2GWQR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_58	1385520.N802_11560	1.598e-12	75.0	2AVSX@1|root,31MKA@2|Bacteria,2INB8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_57	1121019.AUMN01000009_gene1867	8.967e-14	76.0	COG3620@1|root,COG3620@2|Bacteria,2GWYK@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158462_k127_844092_16	1461694.ATO9_21845	1.596e-97	323.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TUY3@28211|Alphaproteobacteria,2PD6N@252301|Oceanicola	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_844092_35	284031.JNXD01000005_gene3396	1.138e-45	175.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158462_k127_844092_50	284031.JNXD01000005_gene3397	1.355e-26	113.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158462_k127_844092_32	710696.Intca_0133	2.979e-56	199.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4FHFR@85021|Intrasporangiaceae	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158462_k127_844092_53	469383.Cwoe_3153	8.702e-20	103.0	COG1309@1|root,COG1309@2|Bacteria,2IGJA@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158462_k127_844092_55	1122939.ATUD01000003_gene3389	6.814e-16	85.0	COG5609@1|root,COG5609@2|Bacteria,2HRNE@201174|Actinobacteria,4CTQM@84995|Rubrobacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2294)	yrhF	-	-	-	-	-	-	-	-	-	-	-	DUF2294
SRR25158462_k127_844092_34	1122939.ATUD01000001_gene125	7.5e-52	188.0	COG5609@1|root,COG5609@2|Bacteria,2HRNE@201174|Actinobacteria,4CTQM@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
SRR25158462_k127_844092_65	1380390.JIAT01000017_gene5314	1.05e-05	53.0	COG1366@1|root,COG1366@2|Bacteria,2HR76@201174|Actinobacteria,4CT33@84995|Rubrobacteria	84995|Rubrobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158462_k127_844092_59	1122939.ATUD01000003_gene3399	1.629e-11	70.0	COG5609@1|root,COG5609@2|Bacteria,2HR3Q@201174|Actinobacteria,4CSZ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
SRR25158462_k127_844092_51	1122939.ATUD01000011_gene2178	1.227e-22	101.0	2E62U@1|root,330RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_49	43354.JOIJ01000023_gene553	4.599e-30	136.0	2CE4Q@1|root,2Z7WX@2|Bacteria,2H0P6@201174|Actinobacteria,4E993@85010|Pseudonocardiales	201174|Actinobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
SRR25158462_k127_844092_14	1283299.AUKG01000001_gene1590	2.543e-113	401.0	2AVWP@1|root,31MQK@2|Bacteria,2HQDE@201174|Actinobacteria,4CRXX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_9	469383.Cwoe_4727	3.635e-143	464.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CRSZ@84995|Rubrobacteria	84995|Rubrobacteria	L	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158462_k127_844092_61	1463887.KL590026_gene2110	8.312e-10	71.0	COG3118@1|root,COG3118@2|Bacteria,2I35R@201174|Actinobacteria	201174|Actinobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
SRR25158462_k127_844092_26	1380390.JIAT01000009_gene1043	3.789e-75	253.0	COG0662@1|root,COG0662@2|Bacteria,2GZ5U@201174|Actinobacteria,4CSXN@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158462_k127_844092_52	765420.OSCT_1110	1.012e-21	99.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158462_k127_844092_30	521011.Mpal_0423	1.079e-68	269.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
SRR25158462_k127_844092_2	469383.Cwoe_0587	5.213e-181	603.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRHB@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_844092_48	1071085.KK033114_gene208	2.095e-30	139.0	COG0428@1|root,arCOG00576@2157|Archaea,2XTDS@28890|Euryarchaeota,23STQ@183963|Halobacteria	183963|Halobacteria	P	divalent heavy-metal cations transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158462_k127_844092_24	1121019.AUMN01000003_gene1012	1.342e-82	282.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,1W8KA@1268|Micrococcaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158462_k127_844092_56	413816.BBJP01000019_gene1368	1.657e-14	84.0	COG1277@1|root,arCOG02436@2157|Archaea,2Y7IQ@28890|Euryarchaeota,241I5@183963|Halobacteria	183963|Halobacteria	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158462_k127_844092_41	517722.AEUE01000001_gene2770	3.051e-39	153.0	2EQUS@1|root,33KPM@2|Bacteria,1QY6Y@1224|Proteobacteria,2URR2@28211|Alphaproteobacteria,2KEN6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_22	1215092.PA6_075_00100	2.833e-84	312.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,1YDGB@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158462_k127_844092_25	1289387.AUKW01000013_gene4088	5.633e-80	276.0	COG2334@1|root,COG2334@2|Bacteria,2I560@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158462_k127_844092_43	1380390.JIAT01000010_gene4926	6.455e-38	162.0	2DMFH@1|root,32R60@2|Bacteria,2IP6I@201174|Actinobacteria,4CT0Q@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_39	1122138.AQUZ01000001_gene1674	3.244e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,2IRNG@201174|Actinobacteria,4DRJR@85009|Propionibacteriales	201174|Actinobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_844092_20	469383.Cwoe_0896	4.547e-85	306.0	COG0739@1|root,COG3409@1|root,COG0739@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,PG_binding_1,Peptidase_M23
SRR25158462_k127_844092_54	1283299.AUKG01000004_gene1115	6.024e-18	89.0	2AXJB@1|root,31PJD@2|Bacteria,2HRXN@201174|Actinobacteria,4CU0X@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_844092_36	1283299.AUKG01000003_gene390	1.529e-45	168.0	COG0346@1|root,COG0346@2|Bacteria,2HR81@201174|Actinobacteria,4CT42@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158462_k127_844092_27	397278.JOJN01000014_gene3603	3.632e-71	245.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4DQD9@85009|Propionibacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158462_k127_844092_45	469383.Cwoe_3842	1.1e-36	145.0	COG0262@1|root,COG0262@2|Bacteria,2HG3A@201174|Actinobacteria,4CTPW@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158462_k127_844092_33	1380390.JIAT01000010_gene3531	2.329e-54	198.0	COG5649@1|root,COG5649@2|Bacteria,2HR6R@201174|Actinobacteria,4CT2N@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158462_k127_844092_5	929712.KI912613_gene3869	1.228e-167	544.0	COG0803@1|root,COG1108@1|root,COG0803@2|Bacteria,COG1108@2|Bacteria,2H2KW@201174|Actinobacteria,4CRG6@84995|Rubrobacteria	84995|Rubrobacteria	P	ABC 3 transport family	-	-	-	-	-	-	-	-	-	-	-	-	ABC-3
SRR25158462_k127_844092_19	469383.Cwoe_4740	6.286e-89	323.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,4CQ2Y@84995|Rubrobacteria	84995|Rubrobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K11710	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR25158462_k127_844092_23	469383.Cwoe_4739	2.524e-83	291.0	COG1108@1|root,COG1108@2|Bacteria,2H1NP@201174|Actinobacteria,4CPWB@84995|Rubrobacteria	84995|Rubrobacteria	P	ABC 3 transport family	-	-	-	-	-	-	-	-	-	-	-	-	ABC-3
SRR25158462_k127_844092_42	469383.Cwoe_4742	7.383e-39	163.0	COG0735@1|root,COG0735@2|Bacteria,2HTHG@201174|Actinobacteria,4CSV2@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158462_k127_844092_13	882082.SaccyDRAFT_0276	9.577e-126	410.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4DZDQ@85010|Pseudonocardiales	201174|Actinobacteria	C	TIGRFAM luciferase family oxidoreductase, group 1	yvbT	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158462_k127_844092_21	469383.Cwoe_4974	1.753e-84	287.0	COG2755@1|root,COG2755@2|Bacteria,2GRDF@201174|Actinobacteria,4CRDK@84995|Rubrobacteria	84995|Rubrobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158462_k127_844092_4	1449346.JQMO01000002_gene894	5.383e-174	569.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,2M05F@2063|Kitasatospora	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_844092_46	35754.JNYJ01000031_gene7002	5.189e-34	136.0	COG1846@1|root,COG1846@2|Bacteria,2IKZB@201174|Actinobacteria,4DG63@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158462_k127_844092_17	710111.FraQA3DRAFT_0657	5.353e-95	329.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4ESJ0@85013|Frankiales	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158462_k127_844092_7	258533.BN977_04029	1.474e-157	514.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,2370B@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158462_k127_844092_37	452863.Achl_0980	3.969e-42	168.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,1WAGQ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_844092_8	324602.Caur_0954	2.981e-151	492.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,375BH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158462_k127_844092_29	1122182.KB903825_gene842	4.087e-70	249.0	COG0671@1|root,COG0671@2|Bacteria,2IAXK@201174|Actinobacteria,4DA2G@85008|Micromonosporales	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SRR25158462_k127_844092_10	1122939.ATUD01000010_gene2876	2.266e-136	460.0	COG2936@1|root,COG2936@2|Bacteria,2H2NT@201174|Actinobacteria,4CQ0K@84995|Rubrobacteria	84995|Rubrobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
SRR25158462_k127_844092_3	251221.35214398	4.974e-178	573.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158462_k127_844092_31	929712.KI912613_gene4491	2.441e-62	234.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158462_k127_844092_38	1158050.KB895457_gene2245	3.224e-41	176.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,1WAGQ@1268|Micrococcaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SRR25158462_k127_844092_47	765952.PUV_18860	8.442e-32	145.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF285,PKD
SRR25158462_k127_844092_28	1380390.JIAT01000010_gene3918	4.651e-71	260.0	COG0446@1|root,COG0446@2|Bacteria,2HQQT@201174|Actinobacteria,4CSDR@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158462_k127_844092_44	469383.Cwoe_0942	4.785e-37	150.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	MA20_09295	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	Pkinase,Usp
SRR25158462_k127_844092_0	1254432.SCE1572_36555	1.76e-226	738.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria,2YW7G@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2101	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158462_k127_844092_11	164757.Mjls_3416	1.256e-132	441.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,237XV@1762|Mycobacteriaceae	201174|Actinobacteria	S	alcohol dehydrogenase	sadh	-	1.1.1.1	ko:K13953,ko:K18382	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158462_k127_844092_12	1298863.AUEP01000013_gene4093	1.748e-130	432.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4DT97@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1,YHS
SRR25158462_k127_844092_15	469383.Cwoe_1860	1.051e-102	344.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CPNM@84995|Rubrobacteria	84995|Rubrobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158462_k127_844092_1	1283299.AUKG01000006_gene757	2.248e-206	662.0	COG1042@1|root,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4CRR1@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-binding	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158462_k127_852583_0	266117.Rxyl_2032	1.63e-90	314.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CPCG@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158462_k127_864273_0	196162.Noca_3475	7.589e-204	636.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4DP0T@85009|Propionibacteriales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158462_k127_864273_2	710686.Mycsm_03934	1.14e-29	125.0	COG0454@1|root,COG0456@2|Bacteria,2I582@201174|Actinobacteria,23A4U@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158462_k127_864273_1	2074.JNYD01000016_gene4244	1.346e-30	127.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,2GNNG@201174|Actinobacteria,4EENS@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
SRR25158462_k127_895112_0	469383.Cwoe_2648	3.604e-104	343.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158462_k127_895112_1	469383.Cwoe_1880	2.646e-25	118.0	COG0739@1|root,COG0739@2|Bacteria,2HP3A@201174|Actinobacteria,4CQEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M23
SRR25158462_k127_895112_3	469383.Cwoe_4526	1.919e-09	63.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,4CPQY@84995|Rubrobacteria	84995|Rubrobacteria	L	type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
SRR25158462_k127_895112_2	521011.Mpal_1345	1.477e-18	100.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
SRR25158462_k127_895112_4	469383.Cwoe_1428	8.575e-05	55.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
SRR25158462_k127_990156_56	1306406.ASHX01000001_gene1826	0.0002769	49.0	COG0642@1|root,COG0745@1|root,COG3290@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG3290@2|Bacteria,2GNWJ@201174|Actinobacteria	201174|Actinobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9,Response_reg
SRR25158462_k127_990156_26	388413.ALPR1_05140	1.76e-75	269.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158462_k127_990156_50	1243664.CAVL020000028_gene140	2.077e-23	107.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,4HIPC@91061|Bacilli,1ZG08@1386|Bacillus	91061|Bacilli	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
SRR25158462_k127_990156_41	469383.Cwoe_5722	6.386e-44	166.0	2BIEE@1|root,32T9G@2|Bacteria,2I86Y@201174|Actinobacteria,4CSVU@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_990156_9	1172181.KB911699_gene1611	4.83e-155	503.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158462_k127_990156_39	156889.Mmc1_1889	5.123e-48	180.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28,2.4.2.44	ko:K00772,ko:K19696	ko00270,ko01100,map00270,map01100	M00034	R01402,R09668	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
SRR25158462_k127_990156_23	156889.Mmc1_1915	5.735e-98	347.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TSZ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158462_k127_990156_11	1122939.ATUD01000005_gene2772	2.08e-144	477.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4CP6Z@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158462_k127_990156_29	1122939.ATUD01000005_gene2771	9.399e-64	229.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,4CPPK@84995|Rubrobacteria	84995|Rubrobacteria	E	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158462_k127_990156_40	1122939.ATUD01000005_gene2770	8.862e-46	183.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria,4CT80@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158462_k127_990156_22	1122939.ATUD01000005_gene2769	4.034e-100	336.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4CPP5@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158462_k127_990156_14	469383.Cwoe_5433	1.114e-135	443.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4CSB4@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158462_k127_990156_46	469383.Cwoe_5432	2.747e-31	128.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4CTAW@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158462_k127_990156_17	469383.Cwoe_1178	1.014e-121	403.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,4CQKV@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158462_k127_990156_45	929712.KI912613_gene3646	1.089e-31	130.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4CT9K@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158462_k127_990156_6	1122939.ATUD01000001_gene231	2.327e-185	591.0	COG0477@1|root,COG0477@2|Bacteria,2I31V@201174|Actinobacteria,4CPF3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158462_k127_990156_37	1122939.ATUD01000015_gene1002	4.118e-51	193.0	COG1226@1|root,COG1226@2|Bacteria,2HPDW@201174|Actinobacteria,4CQRY@84995|Rubrobacteria	84995|Rubrobacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
SRR25158462_k127_990156_0	469383.Cwoe_1140	0.0	1098.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CP6D@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158462_k127_990156_42	1122939.ATUD01000002_gene1461	3.905e-42	170.0	COG0791@1|root,COG4942@1|root,COG0791@2|Bacteria,COG4942@2|Bacteria,2HRBC@201174|Actinobacteria,4CT8J@84995|Rubrobacteria	84995|Rubrobacteria	DM	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_990156_44	469383.Cwoe_0856	1.24e-37	145.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158462_k127_990156_27	469383.Cwoe_2995	3.158e-66	234.0	COG0566@1|root,COG0566@2|Bacteria,2GJ7P@201174|Actinobacteria	201174|Actinobacteria	J	SpoU rRNA Methylase family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158462_k127_990156_32	1121406.JAEX01000001_gene518	1.25e-56	216.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S7S@68525|delta/epsilon subdivisions,2WNFR@28221|Deltaproteobacteria,2M9XW@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRR25158462_k127_990156_19	110319.CF8_1483	6.834e-120	404.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DPUK@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	cotA	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158462_k127_990156_35	1122939.ATUD01000001_gene148	5.923e-53	188.0	COG0346@1|root,COG0346@2|Bacteria,2IIM8@201174|Actinobacteria,4CQQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158462_k127_990156_48	1033736.CAHK01000029_gene1381	6.576e-29	122.0	2CCXQ@1|root,32RWN@2|Bacteria,2IS2D@201174|Actinobacteria	201174|Actinobacteria	S	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
SRR25158462_k127_990156_10	1283299.AUKG01000001_gene1833	1.041e-154	513.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158462_k127_990156_33	469383.Cwoe_0900	3.397e-55	196.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4CT93@84995|Rubrobacteria	84995|Rubrobacteria	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158462_k127_990156_5	469383.Cwoe_0899	1.104e-217	687.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CS9X@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158462_k127_990156_47	1382306.JNIM01000001_gene3144	7.272e-31	124.0	COG1324@1|root,COG1324@2|Bacteria,2G76K@200795|Chloroflexi	200795|Chloroflexi	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158462_k127_990156_20	1380390.JIAT01000010_gene4557	2.086e-119	401.0	COG0842@1|root,COG0842@2|Bacteria,2ICWC@201174|Actinobacteria,4CS9I@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158462_k127_990156_21	1380390.JIAT01000010_gene4556	5.824e-119	394.0	COG1131@1|root,COG1131@2|Bacteria,2IBZE@201174|Actinobacteria,4CPJZ@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158462_k127_990156_55	935866.JAER01000035_gene3235	2.055e-11	71.0	COG1525@1|root,COG2333@1|root,COG1525@2|Bacteria,COG2333@2|Bacteria,2HNFC@201174|Actinobacteria,4DVET@85009|Propionibacteriales	201174|Actinobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
SRR25158462_k127_990156_25	1283299.AUKG01000001_gene1927	9.599e-91	307.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4CQ1C@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158462_k127_990156_51	1122182.KB903814_gene3569	1.987e-22	98.0	2CA4F@1|root,33DCB@2|Bacteria,2GRQ2@201174|Actinobacteria,4DG72@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_990156_30	469383.Cwoe_1599	5.169e-62	237.0	2DM8B@1|root,325JJ@2|Bacteria,2HF4F@201174|Actinobacteria,4CSFB@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
SRR25158462_k127_990156_16	1206101.AZXC01000038_gene1390	1.618e-126	407.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria	201174|Actinobacteria	S	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158462_k127_990156_2	469383.Cwoe_2712	1.397e-264	823.0	COG4799@1|root,COG4799@2|Bacteria,2I46V@201174|Actinobacteria,4CRHW@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158462_k127_990156_7	469383.Cwoe_2374	2.121e-167	535.0	COG3177@1|root,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria	201174|Actinobacteria	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
SRR25158462_k127_990156_52	1333998.M2A_2748	3.572e-18	90.0	COG3794@1|root,COG3794@2|Bacteria,1RI9G@1224|Proteobacteria,2U7KA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158462_k127_990156_18	469383.Cwoe_4241	1.581e-121	417.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4CRVY@84995|Rubrobacteria	84995|Rubrobacteria	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158462_k127_990156_3	227882.SAV_3601	6.573e-242	754.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3432c	Pyridoxal_deC
SRR25158462_k127_990156_15	469383.Cwoe_0910	4.133e-129	416.0	COG2220@1|root,COG2220@2|Bacteria,2GMTR@201174|Actinobacteria,4CRDQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158462_k127_990156_38	1214101.BN159_0944	8.087e-50	188.0	COG4803@1|root,COG4803@2|Bacteria,2IIN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_990156_49	1429046.RR21198_1977	9.976e-28	114.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,4G39Q@85025|Nocardiaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158462_k127_990156_28	1137269.AZWL01000006_gene6731	2.238e-64	232.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158462_k127_990156_53	1298863.AUEP01000022_gene1867	6.061e-18	88.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158462_k127_990156_4	103733.JNYO01000082_gene4551	2.066e-240	765.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DYVW@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158462_k127_990156_54	696281.Desru_3851	1.092e-14	77.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,262DN@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158462_k127_990156_43	469383.Cwoe_3402	5.228e-39	164.0	2B412@1|root,31WRB@2|Bacteria,2HY97@201174|Actinobacteria,4CQGQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158462_k127_990156_13	1380390.JIAT01000010_gene3875	8.413e-140	463.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4CU6T@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158462_k127_990156_36	469383.Cwoe_1298	1.001e-51	204.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4CRXE@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158462_k127_990156_24	1439940.BAY1663_00818	4.767e-95	320.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the carbamate kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_0454,iECED1_1282.ECED1_0540,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641	AA_kinase
SRR25158462_k127_990156_1	1089544.KB912942_gene1761	0.0	1091.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E1HP@85010|Pseudonocardiales	201174|Actinobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,HAD,Hydrolase,Hydrolase_3
SRR25158462_k127_990156_12	58123.JOFJ01000027_gene2789	3.79e-143	466.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4EFPC@85012|Streptosporangiales	201174|Actinobacteria	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158462_k127_990156_8	58123.JOFJ01000027_gene2790	4.239e-164	530.0	COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4EN0D@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158462_k127_990156_34	1122939.ATUD01000003_gene3521	3.395e-54	203.0	COG2197@1|root,COG2197@2|Bacteria,2IIZS@201174|Actinobacteria,4CRXE@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158462_k127_990156_31	469383.Cwoe_1304	3.279e-58	209.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4CRR1@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-binding	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
## 2605 queries scanned
## Total time (seconds): 6.620077133178711
## Rate: 393.50 q/s