## Thu Feb 19 06:40:58 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/SRR25158463_bin.5.fa -m mmseqs --output SRR25158463_bin.5 --output_dir /data/result/bins/wyx/eggqs50+/SRR25158463_bin.5 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158463_k127_1004813_5	1193181.BN10_680093	8.787e-43	160.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4FEDY@85021|Intrasporangiaceae	201174|Actinobacteria	L	RNA helicase	rhlE1	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158463_k127_1004813_0	1386089.N865_16305	8.172e-188	597.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4FF9A@85021|Intrasporangiaceae	201174|Actinobacteria	H	The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are	moeB	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158463_k127_1004813_4	44060.JODL01000001_gene3224	1.763e-76	267.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_1004813_7	1385518.N798_16110	1.614e-20	94.0	2E3M2@1|root,32YJA@2|Bacteria,2HXUV@201174|Actinobacteria,4FHSG@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRR25158463_k127_1004813_6	1172188.KB911821_gene1719	1.277e-32	131.0	COG2261@1|root,COG2261@2|Bacteria,2HM1D@201174|Actinobacteria,4FHSN@85021|Intrasporangiaceae	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1004813_2	1172188.KB911821_gene1720	1.069e-90	305.0	COG3396@1|root,COG3396@2|Bacteria,2GKXZ@201174|Actinobacteria,4FFQB@85021|Intrasporangiaceae	201174|Actinobacteria	S	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like	-	-	-	-	-	-	-	-	-	-	-	-	MiaE_2
SRR25158463_k127_1004813_1	326424.FRAAL2486	2.352e-94	316.0	COG0500@1|root,COG2226@2|Bacteria,2GNVG@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158463_k127_1004813_3	1386089.N865_16280	1.681e-80	274.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4FE9C@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158463_k127_1027384_0	367299.JOEE01000008_gene458	7.392e-193	613.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4FEUI@85021|Intrasporangiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158463_k127_1027384_1	1193181.BN10_810020	1.385e-36	150.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4FFN0@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158463_k127_1027384_2	1193181.BN10_810021	1.975e-20	92.0	2ASDR@1|root,31HT7@2|Bacteria,2GZEA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1027384_3	471852.Tcur_1819	6.783e-06	49.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,4EMH1@85012|Streptosporangiales	201174|Actinobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,F420H2_quin_red
SRR25158463_k127_1051569_5	222534.KB893717_gene2152	2.339e-33	146.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158463_k127_1051569_2	1386089.N865_18285	3.832e-80	279.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4FF1C@85021|Intrasporangiaceae	201174|Actinobacteria	S	Phenazine biosynthesis protein PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158463_k127_1051569_3	1385521.N803_07870	1.194e-76	267.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4FGUS@85021|Intrasporangiaceae	201174|Actinobacteria	G	phosphoglycerate mutase	gpm2	GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158463_k127_1051569_4	234621.RER_28760	2.431e-44	174.0	2EUVM@1|root,33NB3@2|Bacteria,2GTGH@201174|Actinobacteria,4G0N0@85025|Nocardiaceae	201174|Actinobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158463_k127_1051569_6	685727.REQ_24160	6.441e-29	123.0	2DNKR@1|root,32Y0D@2|Bacteria,2GUFW@201174|Actinobacteria,4G0UH@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1051569_0	1121385.AQXW01000004_gene996	1.201e-232	731.0	COG2170@1|root,COG2170@2|Bacteria,2GKCT@201174|Actinobacteria	201174|Actinobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158463_k127_1051569_1	1386089.N865_13695	5.812e-174	567.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4FF74@85021|Intrasporangiaceae	201174|Actinobacteria	O	Thioredoxin reductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
SRR25158463_k127_1051569_7	1532558.JL39_08530	6.074e-12	68.0	COG1765@1|root,COG1765@2|Bacteria,1NVUS@1224|Proteobacteria,2URXQ@28211|Alphaproteobacteria,4BFTG@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	attW	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158463_k127_1061297_4	1380346.JNIH01000004_gene2282	6.494e-131	426.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1
SRR25158463_k127_1061297_0	1172188.KB911821_gene1330	1.248e-154	503.0	COG0534@1|root,COG0534@2|Bacteria,2HXAD@201174|Actinobacteria,4FG20@85021|Intrasporangiaceae	201174|Actinobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158463_k127_1061297_2	196162.Noca_3975	4.219e-139	458.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4DPPD@85009|Propionibacteriales	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158463_k127_1061297_3	1184609.KILIM_073_00300	3.647e-137	446.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria	201174|Actinobacteria	M	Protein containing von Willebrand factor type A (VWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158463_k127_1061297_1	1380370.JIBA01000011_gene3071	2.687e-148	475.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4FEEE@85021|Intrasporangiaceae	201174|Actinobacteria	O	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158463_k127_1080204_4	1386089.N865_08010	1.121e-120	404.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,4FEKB@85021|Intrasporangiaceae	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158463_k127_1080204_2	1385518.N798_14990	2.578e-173	552.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,2GJDH@201174|Actinobacteria,4FFIF@85021|Intrasporangiaceae	201174|Actinobacteria	E	phosphoserine phosphatase	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
SRR25158463_k127_1080204_3	1385518.N798_14995	4.901e-139	445.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,4FF7S@85021|Intrasporangiaceae	201174|Actinobacteria	C	tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_1080204_0	1386089.N865_07990	2.132e-208	653.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4FEM7@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158463_k127_1080204_1	1380370.JIBA01000013_gene1493	4.219e-200	627.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4FE4I@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase family 1	glgA	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_1085596_7	1385518.N798_01150	1.096e-45	172.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4FE4R@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the GARS family	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158463_k127_1085596_5	1184609.KILIM_022_00650	9.851e-49	188.0	COG2197@1|root,COG2197@2|Bacteria,2I10Z@201174|Actinobacteria,4F7M1@85018|Dermatophilaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158463_k127_1085596_0	1172188.KB911820_gene3062	1.685e-312	974.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4FEQ0@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2
SRR25158463_k127_1085596_3	1121017.AUFG01000032_gene426	3.13e-108	364.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4FG5Q@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N,LacI
SRR25158463_k127_1085596_1	1386089.N865_05750	1.942e-235	753.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4FE3G@85021|Intrasporangiaceae	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158463_k127_1085596_6	313589.JNB_15673	3.656e-46	177.0	COG2197@1|root,COG2197@2|Bacteria,2HXJS@201174|Actinobacteria,4FH7N@85021|Intrasporangiaceae	201174|Actinobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1085596_8	1385520.N802_06930	1.707e-39	151.0	COG0346@1|root,COG0346@2|Bacteria,2IQJB@201174|Actinobacteria,4FHUH@85021|Intrasporangiaceae	201174|Actinobacteria	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_1085596_4	710696.Intca_3264	9e-51	184.0	2DMMI@1|root,32SFN@2|Bacteria,2IKP6@201174|Actinobacteria,4FH0D@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
SRR25158463_k127_1085596_2	313589.JNB_15663	4.55e-182	578.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4FFJT@85021|Intrasporangiaceae	201174|Actinobacteria	G	Fructose-bisphosphate aldolase	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158463_k127_1085596_9	471853.Bcav_3762	4.03e-39	150.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_1115752_2	1380370.JIBA01000015_gene37	1.17e-51	189.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2GJMC@201174|Actinobacteria,4FF3I@85021|Intrasporangiaceae	201174|Actinobacteria	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
SRR25158463_k127_1115752_1	471852.Tcur_1214	1.706e-259	818.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4EFI5@85012|Streptosporangiales	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158463_k127_1115752_0	1122138.AQUZ01000001_gene1652	3.502e-260	841.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4DNPC@85009|Propionibacteriales	201174|Actinobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158463_k127_1122406_0	1122138.AQUZ01000021_gene8605	7.213e-187	604.0	COG4147@1|root,COG4147@2|Bacteria,2GM3H@201174|Actinobacteria,4DPRK@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158463_k127_1122406_4	1122138.AQUZ01000021_gene8604	2.645e-29	123.0	2E3NY@1|root,32YM2@2|Bacteria,2II83@201174|Actinobacteria,4DS5Y@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1122406_2	1089455.MOPEL_020_00510	1.028e-100	334.0	COG3279@1|root,COG3279@2|Bacteria,2GKK5@201174|Actinobacteria,4F67H@85018|Dermatophilaceae	201174|Actinobacteria	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
SRR25158463_k127_1122406_1	313589.JNB_09789	1.692e-153	494.0	COG3275@1|root,COG3275@2|Bacteria,2GJD4@201174|Actinobacteria,4FE5E@85021|Intrasporangiaceae	201174|Actinobacteria	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,His_kinase
SRR25158463_k127_1122406_3	1172188.KB911826_gene205	4.934e-81	278.0	COG3177@1|root,COG3177@2|Bacteria,2GIT8@201174|Actinobacteria,4FFUU@85021|Intrasporangiaceae	201174|Actinobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SRR25158463_k127_1122406_5	1184609.KILIM_116_00010	1.637e-21	105.0	COG2894@1|root,COG2894@2|Bacteria	2|Bacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,ParA
SRR25158463_k127_1134467_5	1048339.KB913029_gene3750	1.136e-46	186.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4EW43@85013|Frankiales	201174|Actinobacteria	O	Subtilase family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158463_k127_1134467_7	1172188.KB911820_gene2708	6.89e-26	112.0	2E301@1|root,32Y0K@2|Bacteria,2GQTM@201174|Actinobacteria,4FHXJ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3072)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3072
SRR25158463_k127_1134467_3	1386089.N865_02380	7.376e-72	254.0	28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4FE7N@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1134467_2	313589.JNB_16178	1.598e-77	266.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4FGT2@85021|Intrasporangiaceae	201174|Actinobacteria	P	phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158463_k127_1134467_0	1386089.N865_02360	3.498e-163	520.0	COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4FFNW@85021|Intrasporangiaceae	201174|Actinobacteria	P	inorganic phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158463_k127_1134467_4	1416752.AYME01000010_gene257	7.666e-71	248.0	COG2367@1|root,COG2367@2|Bacteria,2I4PD@201174|Actinobacteria,4FKYJ@85023|Microbacteriaceae	201174|Actinobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158463_k127_1134467_1	1001240.GY21_06050	2.891e-157	508.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4FKW8@85023|Microbacteriaceae	201174|Actinobacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158463_k127_1134467_6	595593.JREV01000031_gene3199	1.984e-41	175.0	COG1619@1|root,COG1619@2|Bacteria,2I358@201174|Actinobacteria	201174|Actinobacteria	V	peptidase U61	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158463_k127_1134467_8	267747.PPA0338	1.996e-13	69.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4DN0B@85009|Propionibacteriales	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158463_k127_1134952_2	1172188.KB911820_gene2386	1.452e-125	415.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4FH2M@85021|Intrasporangiaceae	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158463_k127_1134952_4	675635.Psed_0412	1.857e-106	353.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4E03G@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158463_k127_1134952_1	1172188.KB911820_gene2388	9.92e-167	537.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FFZ1@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158463_k127_1134952_5	1172188.KB911820_gene2389	2.302e-97	328.0	COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria,4FH1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158463_k127_1134952_0	1172188.KB911820_gene2391	2.324e-251	797.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4FHGP@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158463_k127_1134952_3	1032480.MLP_13460	1.366e-112	374.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158463_k127_1134952_6	1380370.JIBA01000010_gene2375	1.669e-26	115.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR25158463_k127_1145255_5	1193181.BN10_1250017	3.024e-40	149.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4FG4P@85021|Intrasporangiaceae	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158463_k127_1145255_2	1385519.N801_12425	4.642e-172	548.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4FG04@85021|Intrasporangiaceae	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158463_k127_1145255_1	1172188.KB911820_gene2248	1.039e-177	572.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4FEU1@85021|Intrasporangiaceae	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158463_k127_1145255_4	710696.Intca_0005	2.286e-63	225.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FGYZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158463_k127_1145255_3	1035308.AQYY01000002_gene234	4.463e-88	304.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,24AGI@186801|Clostridia,2637W@186807|Peptococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158463_k127_1145255_0	1210046.B277_07131	1.651e-277	862.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4FEAB@85021|Intrasporangiaceae	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158463_k127_1184304_1	1394178.AWOO02000002_gene1755	2.574e-107	371.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4EHY7@85012|Streptosporangiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158463_k127_1184304_3	1122605.KB893637_gene3262	7.565e-62	225.0	COG0111@1|root,COG0111@2|Bacteria,4NE9J@976|Bacteroidetes	976|Bacteroidetes	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
SRR25158463_k127_1184304_0	1122605.KB893637_gene3261	2.058e-107	368.0	COG4948@1|root,COG4948@2|Bacteria,4NIIJ@976|Bacteroidetes,1IQE9@117747|Sphingobacteriia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158463_k127_1184304_2	1380370.JIBA01000017_gene3003	6.324e-76	263.0	COG2852@1|root,COG2852@2|Bacteria,2GNZQ@201174|Actinobacteria,4FG2I@85021|Intrasporangiaceae	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158463_k127_1198008_4	1123023.JIAI01000001_gene6107	2.17e-83	280.0	COG1028@1|root,COG1028@2|Bacteria,2I8MC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	bphB	-	1.3.1.87	ko:K05711,ko:K18255	ko00360,ko00624,ko01120,ko01220,map00360,map00624,map01120,map01220	M00545,M00636	R06784,R06785,R09228	RC00534	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
SRR25158463_k127_1198008_3	1114959.SZMC14600_08994	2.674e-88	306.0	COG0235@1|root,COG0235@2|Bacteria,2HEDG@201174|Actinobacteria	201174|Actinobacteria	G	Class II aldolase adducin family protein	-	-	4.1.1.69	ko:K18256	ko00624,ko01120,map00624,map01120	M00636	R01634	RC00569	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158463_k127_1198008_5	1122611.KB903943_gene1553	2.566e-78	282.0	COG1414@1|root,COG1414@2|Bacteria,2HGKS@201174|Actinobacteria,4EPN6@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158463_k127_1198008_2	710696.Intca_1827	5.056e-98	329.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4FISE@85021|Intrasporangiaceae	201174|Actinobacteria	E	HMGL-like	-	-	4.1.3.4,4.1.3.46	ko:K01640,ko:K18314	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090,R10674	RC00502,RC00503,RC01118,RC01205,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158463_k127_1198008_11	420662.Mpe_A2657	6.585e-31	130.0	COG2128@1|root,COG2128@2|Bacteria,1RI8R@1224|Proteobacteria,2W5ZT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158463_k127_1198008_9	398525.KB900701_gene7546	6.405e-55	202.0	COG4126@1|root,COG4126@2|Bacteria,1R9KP@1224|Proteobacteria,2UC15@28211|Alphaproteobacteria,3K68G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1198008_6	1394178.AWOO02000004_gene2438	5.403e-71	246.0	COG1802@1|root,COG1802@2|Bacteria,2GMI2@201174|Actinobacteria,4EK5H@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158463_k127_1198008_12	711393.AYRX01000086_gene5173	4.268e-17	91.0	2BZD4@1|root,332J5@2|Bacteria,2IPP3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1198008_8	557599.MKAN_15425	5.334e-61	229.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1198008_0	1123023.JIAI01000001_gene6640	5.187e-194	616.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4DZDE@85010|Pseudonocardiales	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
SRR25158463_k127_1198008_10	1223523.H340_23883	2.891e-37	160.0	COG1414@1|root,COG1414@2|Bacteria,2GMEA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	sdrB	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158463_k127_1198008_1	1078020.KEK_13743	5.877e-178	567.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,235XH@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158463_k127_1198008_13	1121017.AUFG01000038_gene814	7.812e-16	83.0	COG4842@1|root,COG4842@2|Bacteria,2GQI8@201174|Actinobacteria,4FHSK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Excreted virulence factor EspC, type VII ESX diderm	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
SRR25158463_k127_1198008_7	1449347.JQLN01000005_gene4865	1.036e-63	226.0	COG3391@1|root,COG3391@2|Bacteria,2I22T@201174|Actinobacteria,2M5YI@2063|Kitasatospora	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1198934_2	710696.Intca_1335	1.023e-101	337.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4FE4Z@85021|Intrasporangiaceae	201174|Actinobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SRR25158463_k127_1198934_1	1380370.JIBA01000002_gene2637	1.793e-113	378.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4FF1U@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158463_k127_1198934_0	1385518.N798_06640	5.453e-117	389.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria,4FFE4@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158463_k127_122008_0	367299.JOEE01000001_gene1986	6.983e-172	542.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4FEEA@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158463_k127_122008_2	436229.JOEH01000030_gene4752	4.061e-115	385.0	COG1819@1|root,COG1819@2|Bacteria,2I97R@201174|Actinobacteria	201174|Actinobacteria	CG	transferase activity, transferring hexosyl groups	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158463_k127_122008_6	1122138.AQUZ01000014_gene6987	6.952e-38	153.0	COG1846@1|root,COG1846@2|Bacteria,2ISIQ@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158463_k127_122008_7	1385520.N802_10550	1.754e-19	102.0	2DRQG@1|root,33CMQ@2|Bacteria,2HXGN@201174|Actinobacteria,4FGNI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3180
SRR25158463_k127_122008_3	710696.Intca_0603	6.934e-112	387.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,2H3G6@201174|Actinobacteria,4FF6S@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158463_k127_122008_4	313589.JNB_09459	2.279e-108	365.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4FF3G@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158463_k127_122008_5	1386089.N865_09035	1.425e-93	314.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4FE4X@85021|Intrasporangiaceae	201174|Actinobacteria	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SRR25158463_k127_122008_1	1385518.N798_13615	2.732e-144	463.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4FECS@85021|Intrasporangiaceae	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158463_k127_1263189_2	1122611.KB904007_gene7754	5.823e-234	738.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4EPHS@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158463_k127_1263189_5	1089455.MOPEL_132_00740	1.554e-96	327.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4F7R1@85018|Dermatophilaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_1263189_0	1386089.N865_17320	5.292e-306	959.0	COG0642@1|root,COG2205@2|Bacteria,2GJKC@201174|Actinobacteria,4FEB6@85021|Intrasporangiaceae	201174|Actinobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRR25158463_k127_1263189_7	1193181.BN10_140063	4.542e-53	193.0	COG2156@1|root,COG2156@2|Bacteria,2GK75@201174|Actinobacteria,4FH24@85021|Intrasporangiaceae	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRR25158463_k127_1263189_1	1206101.AZXC01000008_gene3030	3.175e-289	922.0	COG2216@1|root,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRR25158463_k127_1263189_3	285535.JOEY01000062_gene9971	4.62e-162	527.0	COG2060@1|root,COG2216@1|root,COG2060@2|Bacteria,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRR25158463_k127_1263189_6	1386089.N865_17295	1.275e-78	270.0	2DM04@1|root,3139Z@2|Bacteria,2IBU0@201174|Actinobacteria,4FEAJ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158463_k127_1263189_4	1120950.KB892775_gene1167	2.826e-122	398.0	COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria,4DNSK@85009|Propionibacteriales	201174|Actinobacteria	E	Membrane dipeptidase (Peptidase family M19)	Dpep	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158463_k127_1273716_3	710696.Intca_1397	1.737e-161	525.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4FEX0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158463_k127_1273716_1	1386089.N865_01470	2.571e-257	801.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4FFD9@85021|Intrasporangiaceae	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158463_k127_1273716_6	1380370.JIBA01000017_gene2987	1.248e-41	160.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4FHCR@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158463_k127_1273716_5	710696.Intca_1387	1.051e-47	172.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4FGXF@85021|Intrasporangiaceae	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158463_k127_1273716_0	1385521.N803_06145	6.985e-280	896.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4FERM@85021|Intrasporangiaceae	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR25158463_k127_1273716_4	1385520.N802_10120	3.854e-103	341.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,4FFAZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
SRR25158463_k127_1273716_2	405948.SACE_5140	2.966e-227	716.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E1QR@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158463_k127_1281355_12	1386089.N865_00790	1.255e-39	151.0	COG3981@1|root,COG3981@2|Bacteria,2IGK9@201174|Actinobacteria,4FH12@85021|Intrasporangiaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158463_k127_1281355_8	1172188.KB911824_gene3397	1.574e-69	256.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FIJE@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158463_k127_1281355_4	1385518.N798_16410	1.076e-198	651.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FE8Z@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158463_k127_1281355_7	1246995.AFR_36705	8.863e-88	299.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria,4DDJM@85008|Micromonosporales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158463_k127_1281355_5	1172188.KB911821_gene1378	2.78e-152	487.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria,4FG80@85021|Intrasporangiaceae	201174|Actinobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158463_k127_1281355_3	1386089.N865_10070	9.468e-211	684.0	COG0477@1|root,COG2814@2|Bacteria,2GMBQ@201174|Actinobacteria,4FJZF@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_1281355_6	543632.JOJL01000055_gene235	3.82e-132	428.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria,4DAIB@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158463_k127_1281355_10	953739.SVEN_3312	7.215e-49	188.0	COG0842@1|root,COG0842@2|Bacteria,2HDDD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158463_k127_1281355_9	1121946.AUAX01000031_gene987	7.797e-60	216.0	COG0842@1|root,COG0842@2|Bacteria,2I8FD@201174|Actinobacteria,4DCAY@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158463_k127_1281355_1	1172188.KB911823_gene341	3.474e-264	833.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FF1W@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_1281355_0	1380370.JIBA01000013_gene1599	8.003e-296	936.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FFM1@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_1281355_11	367299.JOEE01000005_gene3506	7.605e-48	196.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4FGRI@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
SRR25158463_k127_1281355_2	1386089.N865_00770	1.62e-260	813.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4FE6P@85021|Intrasporangiaceae	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158463_k127_1281355_13	367299.JOEE01000005_gene3508	5.164e-30	126.0	2EGC7@1|root,33A40@2|Bacteria,2HXV4@201174|Actinobacteria,4FHTW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Tryptophan-associated transmembrane protein (Trp_oprn_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_oprn_chp
SRR25158463_k127_1281355_14	1386089.N865_00760	1.268e-12	79.0	290XR@1|root,2ZNJH@2|Bacteria,2GPXK@201174|Actinobacteria,4FHG9@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1281355_15	1394178.AWOO02000007_gene3223	0.0001377	52.0	COG1714@1|root,COG1714@2|Bacteria,2HGSH@201174|Actinobacteria,4EQY1@85012|Streptosporangiales	201174|Actinobacteria	S	RDD family	pra	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158463_k127_1287059_17	1294143.H681_06935	4.768e-05	52.0	2DMP1@1|root,32SS8@2|Bacteria,1NC27@1224|Proteobacteria,1SBA3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SRR25158463_k127_1287059_9	1032480.MLP_46210	4.294e-63	229.0	arCOG11292@1|root,309SY@2|Bacteria,2GTQ8@201174|Actinobacteria,4DVKK@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1287059_16	1120954.ATXE01000004_gene273	1.248e-31	132.0	COG2259@1|root,COG2259@2|Bacteria,2GV27@201174|Actinobacteria	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158463_k127_1287059_5	1386089.N865_18225	1.514e-76	261.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4FG5F@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158463_k127_1287059_11	1385521.N803_07810	1.526e-59	225.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4FFPN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158463_k127_1287059_14	1386089.N865_18235	1.782e-50	189.0	COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4FGYG@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
SRR25158463_k127_1287059_8	1121017.AUFG01000005_gene985	2.052e-72	252.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4FEXI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158463_k127_1287059_12	1385521.N803_07825	2.469e-57	202.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4FGP8@85021|Intrasporangiaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158463_k127_1287059_13	1172188.KB911823_gene591	2.257e-56	201.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4FH2P@85021|Intrasporangiaceae	201174|Actinobacteria	T	Signal peptide protein	garA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158463_k127_1287059_6	1172188.KB911823_gene590	9.137e-76	270.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4FGAD@85021|Intrasporangiaceae	201174|Actinobacteria	K	MerR family	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158463_k127_1287059_10	1172188.KB911823_gene589	2.573e-62	234.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4FGHI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158463_k127_1287059_3	1172188.KB911823_gene588	3.12e-98	323.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4FERH@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158463_k127_1287059_0	1172188.KB911823_gene587	0.0	1477.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria,4FF6T@85021|Intrasporangiaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SRR25158463_k127_1287059_1	1172188.KB911820_gene2372	5.656e-121	398.0	COG5322@1|root,COG5322@2|Bacteria,2IEVX@201174|Actinobacteria,4FHDM@85021|Intrasporangiaceae	201174|Actinobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Semialdhyde_dh,Shikimate_DH
SRR25158463_k127_1287059_2	1380370.JIBA01000010_gene2385	4.601e-119	422.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4FIK3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158463_k127_1287059_15	1380354.JIAN01000008_gene3438	1.412e-41	163.0	2F7CT@1|root,33ZTV@2|Bacteria,2H68E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1287059_4	1032480.MLP_00830	4.007e-89	302.0	COG3945@1|root,COG3945@2|Bacteria,2GQQY@201174|Actinobacteria,4DS52@85009|Propionibacteriales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158463_k127_1287059_7	1380356.JNIK01000014_gene3372	1.807e-73	258.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EUW7@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,Trans_reg_C
SRR25158463_k127_12901_10	1304865.JAGF01000001_gene1987	7.94e-33	127.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4F0EC@85016|Cellulomonadaceae	201174|Actinobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158463_k127_12901_8	1463861.JNXE01000072_gene2134	2.57e-46	181.0	2BVX8@1|root,30QZQ@2|Bacteria,2GZ2G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_12901_2	1386089.N865_18390	2.828e-212	662.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4FEQQ@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the synthesis of xanthosine monophosphate by the NAD dependent oxidation of inosine monophosphate	guaB3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158463_k127_12901_4	1274.HX89_00125	4.706e-141	459.0	COG0726@1|root,COG0726@2|Bacteria,2GKIX@201174|Actinobacteria,1ZVVI@145357|Dermacoccaceae	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_12901_0	1386089.N865_18400	3.185e-285	893.0	COG1132@1|root,COG1132@2|Bacteria,2GJ8B@201174|Actinobacteria,4FEWF@85021|Intrasporangiaceae	201174|Actinobacteria	V	Multidrug ABC transporter ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_12901_1	1380370.JIBA01000016_gene775	1.727e-245	769.0	COG1132@1|root,COG1132@2|Bacteria,2GJAP@201174|Actinobacteria,4FF0Q@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_12901_6	479435.Kfla_4382	3.86e-110	392.0	COG2807@1|root,COG2807@2|Bacteria,2I2KJ@201174|Actinobacteria	201174|Actinobacteria	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_12901_7	543632.JOJL01000010_gene7243	2.518e-101	336.0	COG1414@1|root,COG1414@2|Bacteria,2GJAZ@201174|Actinobacteria,4DB8I@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	gylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158463_k127_12901_5	543632.JOJL01000010_gene7244	9.633e-111	368.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4DG5A@85008|Micromonosporales	201174|Actinobacteria	G	Major intrinsic protein	-	-	-	ko:K02440,ko:K06188,ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.12,1.A.8.2	-	-	MIP
SRR25158463_k127_12901_3	543632.JOJL01000010_gene7245	4.89e-176	556.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4DBPP@85008|Micromonosporales	201174|Actinobacteria	G	Dihydroxyacetone kinase	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1
SRR25158463_k127_12901_9	477641.MODMU_5202	1.811e-35	144.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4EVEA@85013|Frankiales	201174|Actinobacteria	S	TIGRFAM dihydroxyacetone kinase, L subunit	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158463_k127_1299662_9	1381751.JAJB01000010_gene2503	8.702e-05	45.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4F8MI@85019|Brevibacteriaceae	201174|Actinobacteria	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158463_k127_1299662_6	35754.JNYJ01000020_gene234	2.133e-16	84.0	COG3237@1|root,COG3237@2|Bacteria,2GQQ4@201174|Actinobacteria,4DFT3@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158463_k127_1299662_4	1385520.N802_16330	1.577e-54	201.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4FGY3@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K02405,ko:K03090	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158463_k127_1299662_8	710696.Intca_2198	1.523e-13	74.0	2EK8X@1|root,33DZ6@2|Bacteria,2GWJW@201174|Actinobacteria,4FI71@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1299662_1	101510.RHA1_ro01289	3.261e-70	246.0	COG3707@1|root,COG3707@2|Bacteria,2GPHP@201174|Actinobacteria,4FWZT@85025|Nocardiaceae	201174|Actinobacteria	K	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_1299662_3	298654.FraEuI1c_0483	6.107e-55	199.0	COG3153@1|root,COG3153@2|Bacteria,2GQ6A@201174|Actinobacteria,4EVFK@85013|Frankiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
SRR25158463_k127_1299662_0	1121017.AUFG01000012_gene1799	9.623e-191	602.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4FG41@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.90	ko:K00895	ko00010,ko00030,ko00051,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map01100,map01110,map01120,map01130	-	R00764,R02073	RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158463_k127_1299662_5	1033730.CAHG01000007_gene2762	1.038e-29	124.0	COG1514@1|root,COG1514@2|Bacteria,2I1K7@201174|Actinobacteria,4DVS3@85009|Propionibacteriales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158463_k127_1299662_2	710696.Intca_3478	7.583e-60	213.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,4FGI8@85021|Intrasporangiaceae	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158463_k127_1299662_7	710696.Intca_3479	2.207e-15	87.0	COG5662@1|root,COG5662@2|Bacteria,2I196@201174|Actinobacteria,4FHP7@85021|Intrasporangiaceae	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158463_k127_130395_9	477641.MODMU_5484	1.499e-62	216.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria	201174|Actinobacteria	IQ	Rhamnulose-1-phosphate aldolase alcohol dehydrogenase	rhaD	-	1.1.1.1,1.1.1.140,4.1.2.19	ko:K00001,ko:K00068,ko:K01629	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R05607,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,adh_short,adh_short_C2
SRR25158463_k127_130395_3	477641.MODMU_5481	3.737e-124	404.0	COG1082@1|root,COG1082@2|Bacteria,2HTYD@201174|Actinobacteria,4EVI9@85013|Frankiales	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
SRR25158463_k127_130395_14	188626.HMPREF0321_1188	1.952e-05	57.0	2CA8H@1|root,3289W@2|Bacteria,2I0WM@201174|Actinobacteria,1ZX3B@145357|Dermacoccaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_130395_8	65497.JODV01000017_gene2978	1.061e-64	228.0	COG1802@1|root,COG1802@2|Bacteria,2GJRM@201174|Actinobacteria,4E325@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158463_k127_130395_1	1380393.JHVP01000004_gene678	3.61e-186	597.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4EU9A@85013|Frankiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_130395_7	396014.BF93_16305	1.639e-95	321.0	COG1028@1|root,COG1028@2|Bacteria,2GX9R@201174|Actinobacteria,4FDPI@85020|Dermabacteraceae	201174|Actinobacteria	IQ	KR domain	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158463_k127_130395_6	1064537.AGSO01000011_gene2842	3.77e-98	339.0	COG1082@1|root,COG1082@2|Bacteria,2I9QD@201174|Actinobacteria,4FDM3@85020|Dermabacteraceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158463_k127_130395_0	1150398.JIBJ01000007_gene76	1.789e-194	632.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria	201174|Actinobacteria	G	Dihydroxyacetone kinase	dhaK2	-	2.7.1.121,2.7.1.210,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878,ko:K20902	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059,R11461	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
SRR25158463_k127_130395_10	435830.HMPREF0045_01002	2.713e-59	217.0	COG0698@1|root,COG0698@2|Bacteria,2IIDQ@201174|Actinobacteria,4D516@85005|Actinomycetales	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	-	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158463_k127_130395_11	1089544.KB912942_gene2408	1.287e-51	201.0	COG1071@1|root,COG1071@2|Bacteria,2I2PM@201174|Actinobacteria,4EDWX@85010|Pseudonocardiales	201174|Actinobacteria	C	Alpha/beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_8
SRR25158463_k127_130395_13	1172188.KB911824_gene3369	7.668e-21	102.0	COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria,4FHMA@85021|Intrasporangiaceae	201174|Actinobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158463_k127_130395_5	1043205.AFYF01000006_gene1497	4.939e-111	364.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4FETR@85021|Intrasporangiaceae	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158463_k127_130395_4	1386089.N865_01700	2.453e-121	397.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4FEKG@85021|Intrasporangiaceae	201174|Actinobacteria	K	NAD-dependent	cobB	-	-	-	-	-	-	-	-	-	-	-	SIR2
SRR25158463_k127_130395_2	1385519.N801_17820	4.016e-131	424.0	COG0583@1|root,COG0583@2|Bacteria,2GKT0@201174|Actinobacteria,4FFNX@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158463_k127_130395_12	710696.Intca_1426	2.374e-23	101.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4FEQ6@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158463_k127_1307049_7	2045.KR76_14670	7.066e-209	660.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4DMZJ@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158463_k127_1307049_8	1172188.KB911823_gene300	5.631e-166	526.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4FEMK@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158463_k127_1307049_15	1385520.N802_16875	5.462e-78	265.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4FFMC@85021|Intrasporangiaceae	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158463_k127_1307049_6	1108045.GORHZ_080_00280	1.131e-212	680.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria,4GBIF@85026|Gordoniaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ABM,FAD_binding_3
SRR25158463_k127_1307049_16	37919.EP51_12315	3.401e-69	261.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria,4FYAB@85025|Nocardiaceae	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158463_k127_1307049_20	1386089.N865_00980	7.948e-58	203.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4FH3C@85021|Intrasporangiaceae	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158463_k127_1307049_13	710696.Intca_1597	1.279e-100	344.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4FEXN@85021|Intrasporangiaceae	201174|Actinobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158463_k127_1307049_14	2074.JNYD01000016_gene4267	1.505e-81	294.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4DZTQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158463_k127_1307049_11	1172188.KB911823_gene293	1.989e-116	383.0	COG3485@1|root,COG3485@2|Bacteria,2GMAP@201174|Actinobacteria,4FF4W@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158463_k127_1307049_9	1386089.N865_01000	1.71e-152	502.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4FEDZ@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158463_k127_1307049_19	1172188.KB911823_gene289	1.186e-61	220.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria,4FGP3@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158463_k127_1307049_5	1193181.BN10_500027	2.791e-213	677.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4FEAA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR25158463_k127_1307049_22	1386089.N865_01015	6.048e-51	192.0	COG1989@1|root,COG1989@2|Bacteria,2HH3Y@201174|Actinobacteria,4FH5M@85021|Intrasporangiaceae	201174|Actinobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
SRR25158463_k127_1307049_17	1386089.N865_01020	4.684e-64	229.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4FEUA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Shikimate	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2552c	Shikimate_DH,Shikimate_dh_N
SRR25158463_k127_1307049_12	710696.Intca_1589	3.344e-101	349.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4FFI0@85021|Intrasporangiaceae	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158463_k127_1307049_21	1386089.N865_01030	7.839e-52	191.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4FGUB@85021|Intrasporangiaceae	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158463_k127_1307049_1	1184609.KILIM_035_00430	0.0	1212.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4F6CN@85018|Dermatophilaceae	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158463_k127_1307049_18	1386969.AWTB01000093_gene4334	2.028e-62	237.0	COG0596@1|root,COG0596@2|Bacteria,2HXH5@201174|Actinobacteria,4GFXH@85026|Gordoniaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158463_k127_1307049_10	1184609.KILIM_029_00030	3.364e-145	488.0	COG4425@1|root,COG4425@2|Bacteria,2GKB5@201174|Actinobacteria,4F7GE@85018|Dermatophilaceae	201174|Actinobacteria	S	Alpha/beta-hydrolase family N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158463_k127_1307049_4	1386089.N865_01065	3.124e-222	697.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4FF0D@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158463_k127_1307049_3	1172188.KB911823_gene276	2.152e-252	799.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4FEVF@85021|Intrasporangiaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158463_k127_1307049_0	471853.Bcav_0356	0.0	1577.0	28JBD@1|root,2Z964@2|Bacteria,2H0C3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1307049_2	471853.Bcav_0357	0.0	1210.0	2DB7D@1|root,2Z7KR@2|Bacteria,2GKFW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1352441_13	1123251.ATWM01000009_gene2915	3.33e-71	248.0	COG4262@1|root,COG4262@2|Bacteria,2I372@201174|Actinobacteria,4FISH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158463_k127_1352441_17	367299.JOEE01000001_gene1470	2.09e-60	216.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4FGB9@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158463_k127_1352441_21	1386089.N865_06980	4.197e-35	141.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4FHDC@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158463_k127_1352441_7	1385521.N803_11380	1.028e-85	287.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4FEK7@85021|Intrasporangiaceae	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158463_k127_1352441_20	1385520.N802_05015	7.348e-50	178.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4FGY5@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158463_k127_1352441_19	313589.JNB_20523	1.43e-50	189.0	2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria,4FI8P@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1352441_4	1172188.KB911820_gene2302	9.167e-125	417.0	COG5650@1|root,COG5650@2|Bacteria,2GJYA@201174|Actinobacteria,4FFXW@85021|Intrasporangiaceae	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158463_k127_1352441_2	1172188.KB911820_gene2301	5.599e-212	681.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4FEIA@85021|Intrasporangiaceae	201174|Actinobacteria	M	Penicillin-binding Protein	pbp5	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158463_k127_1352441_14	1123320.KB889730_gene6028	4.389e-64	250.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158463_k127_1352441_3	1193181.BN10_480011	1.116e-208	652.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4FE7S@85021|Intrasporangiaceae	201174|Actinobacteria	I	synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158463_k127_1352441_12	1172188.KB911825_gene3524	1.143e-71	256.0	COG2852@1|root,COG2852@2|Bacteria,2IGEW@201174|Actinobacteria,4FGF6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_1352441_16	1240349.ANGC01000006_gene1363	4.881e-61	216.0	COG3467@1|root,COG3467@2|Bacteria,2IIWQ@201174|Actinobacteria,4G1S6@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_1352441_18	1380370.JIBA01000010_gene2439	2.162e-52	212.0	COG1404@1|root,COG1404@2|Bacteria,2GNIX@201174|Actinobacteria,4FJ3N@85021|Intrasporangiaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158463_k127_1352441_0	1386089.N865_06930	4.243e-242	784.0	COG2909@1|root,COG4995@1|root,COG2909@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4FFZZ@85021|Intrasporangiaceae	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158463_k127_1352441_15	710696.Intca_3627	4.398e-64	230.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4FGFX@85021|Intrasporangiaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158463_k127_1352441_11	1385519.N801_01560	9.301e-78	268.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4FFZG@85021|Intrasporangiaceae	201174|Actinobacteria	T	Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
SRR25158463_k127_1352441_1	1386089.N865_11845	1.208e-239	748.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4FEKK@85021|Intrasporangiaceae	201174|Actinobacteria	J	RNA nucleotidyltransferase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158463_k127_1352441_9	1385520.N802_04890	2.186e-79	267.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4FEIH@85021|Intrasporangiaceae	201174|Actinobacteria	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158463_k127_1352441_6	1386089.N865_11885	2.606e-106	374.0	COG1361@1|root,COG1361@2|Bacteria,2I7FT@201174|Actinobacteria,4FK24@85021|Intrasporangiaceae	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1352441_5	710696.Intca_3634	3.087e-107	374.0	COG0515@1|root,COG0515@2|Bacteria,2GM4A@201174|Actinobacteria,4FEWE@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158463_k127_1352441_10	1184609.KILIM_019_00780	8.455e-79	279.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4F7UJ@85018|Dermatophilaceae	201174|Actinobacteria	K	ECF sigma factor	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_1352441_23	1380370.JIBA01000010_gene2460	6.3e-24	113.0	2FKX8@1|root,34CHG@2|Bacteria,2IIPP@201174|Actinobacteria,4FHQP@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1352441_8	1210046.B277_07021	2.713e-82	278.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4FEXJ@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158463_k127_1364688_3	208439.AJAP_35805	6.026e-46	172.0	COG0174@1|root,COG0174@2|Bacteria,2IFHQ@201174|Actinobacteria,4E3CW@85010|Pseudonocardiales	201174|Actinobacteria	E	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158463_k127_1364688_1	1121017.AUFG01000003_gene3358	1.928e-88	308.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4FFF2@85021|Intrasporangiaceae	201174|Actinobacteria	S	integral membrane protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158463_k127_1364688_0	710696.Intca_3413	2.035e-320	1006.0	COG1131@1|root,COG2936@1|root,COG1131@2|Bacteria,COG2936@2|Bacteria,2GN8P@201174|Actinobacteria,4FF6G@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,PepX_C,Peptidase_S15
SRR25158463_k127_1364688_2	452863.Achl_3433	2.891e-47	173.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,1W8KK@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_1378028_3	1122138.AQUZ01000003_gene399	1.477e-69	248.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4DQNH@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158463_k127_1378028_1	65497.JODV01000006_gene750	8.754e-137	447.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4E0JW@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158463_k127_1378028_0	1380390.JIAT01000013_gene216	6.659e-208	662.0	COG3459@1|root,COG3459@2|Bacteria,2IA66@201174|Actinobacteria,4CS35@84995|Rubrobacteria	84995|Rubrobacteria	G	Protein of unknown function (DUF3131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glycoamylase
SRR25158463_k127_1378028_2	1454010.JEOE01000044_gene1541	5.276e-110	365.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158463_k127_13836_2	1172188.KB911824_gene3203	4.776e-40	153.0	2E9Y4@1|root,3343S@2|Bacteria,2GR3H@201174|Actinobacteria,4FHBJ@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_13836_3	1172188.KB911824_gene3204	7.865e-38	149.0	2EBSZ@1|root,335SP@2|Bacteria,2IS2J@201174|Actinobacteria,4FH9T@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158463_k127_13836_4	644282.Deba_2599	8.508e-28	125.0	COG0454@1|root,COG0454@2|Bacteria,1RHV9@1224|Proteobacteria,43BMR@68525|delta/epsilon subdivisions,2X6ZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_13836_6	935567.JAES01000022_gene2449	3.438e-05	51.0	COG4453@1|root,COG4453@2|Bacteria,1N33F@1224|Proteobacteria,1SB68@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
SRR25158463_k127_13836_1	1032480.MLP_34460	2.269e-47	188.0	28MCN@1|root,2ZAQR@2|Bacteria,2GXXM@201174|Actinobacteria,4DW15@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_13836_5	1151061.CAJY01000020_gene4243	3.173e-22	111.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
SRR25158463_k127_13836_0	1435356.Y013_16280	5.51e-88	295.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4FVF3@85025|Nocardiaceae	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	ethA	-	-	ko:K10215	ko00627,ko01120,map00627,map01120	-	R07836,R07837	RC02100,RC03121	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
SRR25158463_k127_1392847_21	1131814.JAFO01000001_gene4611	9.068e-53	199.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158463_k127_1392847_3	1172188.KB911821_gene1669	7.601e-177	565.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4FEA3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Malate dehydrogenase	mez_1	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158463_k127_1392847_4	1380370.JIBA01000016_gene694	3.256e-133	430.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158463_k127_1392847_2	1380370.JIBA01000016_gene695	1.311e-185	589.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4FFNH@85021|Intrasporangiaceae	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158463_k127_1392847_13	479431.Namu_0487	5.66e-91	303.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EUCS@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158463_k127_1392847_10	1283283.ATXA01000012_gene4779	7.692e-96	331.0	COG4585@1|root,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria,4EUEN@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
SRR25158463_k127_1392847_0	543632.JOJL01000009_gene6043	6.851e-265	854.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4DCD5@85008|Micromonosporales	201174|Actinobacteria	G	Alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
SRR25158463_k127_1392847_25	1237500.ANBA01000021_gene5310	2.217e-28	119.0	2FCGD@1|root,344JU@2|Bacteria,2IRV1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1392847_7	1237500.ANBA01000021_gene5311	7.121e-108	362.0	COG2197@1|root,COG2197@2|Bacteria,2IBK0@201174|Actinobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158463_k127_1392847_24	1519464.HY22_00525	3.002e-32	139.0	COG1028@1|root,COG1028@2|Bacteria	1519464.HY22_00525|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1392847_20	1120949.KB903323_gene3244	9.547e-55	198.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_1392847_22	1120949.KB903323_gene3243	6.182e-43	162.0	COG1846@1|root,COG1846@2|Bacteria,2INEU@201174|Actinobacteria	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
SRR25158463_k127_1392847_14	675635.Psed_6392	1.588e-90	306.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	ycgS	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158463_k127_1392847_8	1123023.JIAI01000002_gene5592	1.331e-104	349.0	COG0500@1|root,COG0500@2|Bacteria,2GM5T@201174|Actinobacteria,4DXIZ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158463_k127_1392847_26	446466.Cfla_3378	2.064e-20	101.0	COG2372@1|root,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K07156,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
SRR25158463_k127_1392847_23	1121272.KB903283_gene4919	3.971e-37	153.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria,4DBMB@85008|Micromonosporales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158463_k127_1392847_9	1463917.JODC01000007_gene7266	3.378e-97	323.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158463_k127_1392847_1	67352.JODS01000027_gene2383	3.068e-193	624.0	COG0457@1|root,COG0457@2|Bacteria,2GMPM@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107
SRR25158463_k127_1392847_5	1385520.N802_06190	2.555e-116	385.0	COG2222@1|root,COG2222@2|Bacteria,2GMCZ@201174|Actinobacteria,4FEF9@85021|Intrasporangiaceae	201174|Actinobacteria	M	sugar isomerase	-	-	-	-	-	-	-	-	-	-	-	-	SIS
SRR25158463_k127_1392847_16	1120950.KB892720_gene1910	4.95e-77	280.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4DR4I@85009|Propionibacteriales	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158463_k127_1392847_18	1449347.JQLN01000007_gene1282	2.016e-68	249.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,2M2KI@2063|Kitasatospora	201174|Actinobacteria	G	pfkB family carbohydrate kinase	lacC	-	2.7.1.144,2.7.1.56	ko:K00882,ko:K00917	ko00051,ko00052,ko01100,map00051,map00052,map01100	-	R02071,R03236	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_1392847_11	1193181.BN10_470019	9.352e-96	328.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4FGIJ@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158463_k127_1392847_6	477641.MODMU_2516	4.078e-112	368.0	COG1404@1|root,COG1404@2|Bacteria,2HS89@201174|Actinobacteria	201174|Actinobacteria	O	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
SRR25158463_k127_1392847_28	224911.27354308	2.932e-10	73.0	29CK5@1|root,2ZZIH@2|Bacteria,1NWJA@1224|Proteobacteria,2USHF@28211|Alphaproteobacteria,3K46I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1392847_15	1283283.ATXA01000008_gene2989	2.918e-85	292.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_1392847_12	1123321.KB905816_gene2414	1.423e-91	310.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158463_k127_1392847_19	1452536.JARE01000016_gene2156	2.459e-65	246.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_1392847_17	1278308.KB907078_gene2038	7.95e-69	240.0	COG0438@1|root,COG0438@2|Bacteria,2IGNQ@201174|Actinobacteria,4FR4V@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158463_k127_1393333_11	367299.JOEE01000006_gene717	2.607e-44	164.0	COG2905@1|root,COG2905@2|Bacteria,2I3M3@201174|Actinobacteria,4FJZR@85021|Intrasporangiaceae	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158463_k127_1393333_1	313589.JNB_16484	9.594e-173	558.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4FE5H@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158463_k127_1393333_10	710696.Intca_2906	2.27e-53	197.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,4FEZ1@85021|Intrasporangiaceae	201174|Actinobacteria	M	Transglycosylase-like domain	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	LysM,Peptidase_M23,Transglycosylas
SRR25158463_k127_1393333_3	1077972.ARGLB_093_00010	6.205e-83	290.0	COG1309@1|root,COG1309@2|Bacteria,2GQRD@201174|Actinobacteria,1WBVH@1268|Micrococcaceae	201174|Actinobacteria	K	transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158463_k127_1393333_13	66377.JOBH01000006_gene162	2.283e-24	105.0	2E62U@1|root,330RX@2|Bacteria,2GTSM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1393333_15	479435.Kfla_1241	2.233e-09	67.0	28ZPD@1|root,2ZMEI@2|Bacteria,2GYSG@201174|Actinobacteria,4DW9G@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1393333_17	477641.MODMU_3041	3.718e-08	59.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158463_k127_1393333_7	2045.KR76_23005	1.285e-63	229.0	COG0789@1|root,COG4250@1|root,COG0789@2|Bacteria,COG4250@2|Bacteria,2IF7P@201174|Actinobacteria,4DPQJ@85009|Propionibacteriales	201174|Actinobacteria	KT	Sensory domain in DIguanylate Cyclases and Two-component system	-	-	-	-	-	-	-	-	-	-	-	-	DICT,MerR_1
SRR25158463_k127_1393333_2	1385520.N802_16380	4.974e-86	292.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4FICB@85021|Intrasporangiaceae	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_1393333_4	326424.FRAAL3886	1.421e-81	286.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_1393333_6	326424.FRAAL3887	6.079e-64	229.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria,4EX0W@85013|Frankiales	201174|Actinobacteria	T	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_1393333_14	1380370.JIBA01000011_gene3350	1.593e-12	74.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_1393333_16	467661.RKLH11_3851	3.191e-08	66.0	COG1376@1|root,COG2931@1|root,COG3291@1|root,COG1376@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3ZICS@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	Q	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	zapA	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	HemolysinCabind,PPC,Peptidase_M10,Peptidase_M10_C,Reprolysin_4,W_rich_C
SRR25158463_k127_1393333_8	1463887.KL590085_gene537	3.117e-59	227.0	COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,VCBS
SRR25158463_k127_1393333_9	1386089.N865_10480	7.049e-59	209.0	COG3832@1|root,COG3832@2|Bacteria,2IE7C@201174|Actinobacteria,4FGXR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_1393333_5	710685.MycrhN_3430	1.663e-73	254.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria,233SA@1762|Mycobacteriaceae	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
SRR25158463_k127_1393333_0	931627.MycrhDRAFT_5812	4.452e-258	806.0	COG0457@1|root,COG0457@2|Bacteria,2HX8A@201174|Actinobacteria,232BB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
SRR25158463_k127_1393333_12	1386089.N865_01885	4.393e-41	157.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4FE57@85021|Intrasporangiaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158463_k127_1416311_3	1385520.N802_08870	4.705e-110	370.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4FEF4@85021|Intrasporangiaceae	201174|Actinobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
SRR25158463_k127_1416311_4	593907.Celgi_2772	1.833e-50	185.0	COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria	201174|Actinobacteria	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158463_k127_1416311_2	1298863.AUEP01000017_gene4107	1.712e-158	511.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DPBM@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158463_k127_1416311_1	1121385.AQXW01000004_gene2180	5.02e-168	533.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,1ZVF3@145357|Dermacoccaceae	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158463_k127_1416311_0	367299.JOEE01000011_gene3179	4.114e-298	930.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4FE74@85021|Intrasporangiaceae	201174|Actinobacteria	G	4-alpha-glucanotransferase	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158463_k127_1416311_5	935866.JAER01000005_gene56	3.296e-43	182.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4DN9R@85009|Propionibacteriales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158463_k127_1421213_4	1172188.KB911821_gene1185	3.317e-29	136.0	COG0776@1|root,COG0776@2|Bacteria,2IQFT@201174|Actinobacteria,4FHGB@85021|Intrasporangiaceae	201174|Actinobacteria	L	regulation of translation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1421213_0	367299.JOEE01000009_gene334	2.887e-247	778.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4FE70@85021|Intrasporangiaceae	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158463_k127_1421213_3	1095767.CAHD01000069_gene3157	8.579e-50	186.0	2DR5D@1|root,33A8R@2|Bacteria,2HXX5@201174|Actinobacteria,4F1HD@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2993
SRR25158463_k127_1421213_1	1386089.N865_16915	5.055e-181	574.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4FE8F@85021|Intrasporangiaceae	201174|Actinobacteria	F	Deoxyguanosinetriphosphate triphosphohydrolase-like protein	dgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158463_k127_1421213_2	408672.NBCG_02655	3.821e-136	449.0	COG2755@1|root,COG2755@2|Bacteria,2HEZV@201174|Actinobacteria,4DTKN@85009|Propionibacteriales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158463_k127_1421213_5	1303692.SFUL_3075	8.736e-25	104.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158463_k127_1487667_3	1385521.N803_00870	4.936e-91	303.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4FEQ8@85021|Intrasporangiaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158463_k127_1487667_7	288705.RSal33209_0721	7.842e-20	97.0	2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,1WA02@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3046)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3046
SRR25158463_k127_1487667_1	1304865.JAGF01000001_gene3757	1.127e-151	484.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158463_k127_1487667_5	367299.JOEE01000009_gene240	5.038e-69	255.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4FENR@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158463_k127_1487667_2	367299.JOEE01000009_gene241	6.52e-117	396.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4FEZ3@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158463_k127_1487667_4	469371.Tbis_1720	3.301e-75	259.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria,4DXTT@85010|Pseudonocardiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158463_k127_1487667_6	446470.Snas_2064	2.94e-64	237.0	COG4585@1|root,COG4585@2|Bacteria,2GKRM@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
SRR25158463_k127_1487667_8	644283.Micau_3289	4.003e-15	86.0	2EFYZ@1|root,339R5@2|Bacteria,2HUQD@201174|Actinobacteria,4DFRQ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1487667_0	1385520.N802_00860	1.267e-201	632.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4FFS1@85021|Intrasporangiaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158463_k127_1491892_4	479431.Namu_0349	1.052e-38	154.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria,4EWTY@85013|Frankiales	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_1491892_2	1380354.JIAN01000010_gene2963	1.689e-96	325.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4F21C@85016|Cellulomonadaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158463_k127_1491892_0	1122622.ATWJ01000013_gene78	2.016e-252	788.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4FIVI@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158463_k127_1491892_1	266940.Krad_2427	6.945e-110	370.0	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158463_k127_1491892_3	1077144.AGFF01000025_gene525	2.131e-89	303.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
SRR25158463_k127_1496660_0	1386089.N865_00875	1.486e-173	553.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4FEFB@85021|Intrasporangiaceae	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158463_k127_1496660_3	1120948.KB903222_gene572	2.121e-82	281.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4E30W@85010|Pseudonocardiales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
SRR25158463_k127_1496660_1	1385520.N802_16980	3.162e-114	370.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4FFG8@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158463_k127_1496660_4	710696.Intca_2653	7.426e-77	284.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4FEFR@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158463_k127_1496660_2	1032480.MLP_03830	6.834e-114	386.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DPZB@85009|Propionibacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158463_k127_1505387_5	1298863.AUEP01000010_gene4505	1.469e-18	85.0	COG0372@1|root,COG0372@2|Bacteria,2H9YP@201174|Actinobacteria,4DSM0@85009|Propionibacteriales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158463_k127_1505387_1	1463926.JOCA01000017_gene438	2.324e-172	542.0	COG3384@1|root,COG3384@2|Bacteria,2GNCA@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158463_k127_1505387_3	1298863.AUEP01000010_gene4503	5.683e-63	218.0	2A2TQ@1|root,30R7G@2|Bacteria,2IMC8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1505387_2	1146883.BLASA_2969	2.191e-93	321.0	COG0604@1|root,COG0604@2|Bacteria,2GMA2@201174|Actinobacteria,4EUZM@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158463_k127_1505387_0	1380386.JIAW01000004_gene361	4.242e-243	776.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,2371U@1762|Mycobacteriaceae	201174|Actinobacteria	G	PTS system fructose IIA component	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N,PTS-HPr
SRR25158463_k127_1505387_4	443218.AS9A_4380	1.435e-33	132.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,236SU@1762|Mycobacteriaceae	201174|Actinobacteria	S	Dak2	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158463_k127_1523472_0	1172188.KB911825_gene3667	1.766e-290	904.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4FF25@85021|Intrasporangiaceae	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158463_k127_1523472_6	367299.JOEE01000007_gene115	1.535e-49	179.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4FGWG@85021|Intrasporangiaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158463_k127_1523472_1	1386089.N865_18355	1.069e-151	489.0	COG1041@1|root,COG1041@2|Bacteria,2I2EV@201174|Actinobacteria,4FK0G@85021|Intrasporangiaceae	201174|Actinobacteria	L	tRNA (guanine-N2-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1523472_5	1223543.GP2_033_00570	1.398e-59	216.0	COG3832@1|root,COG3832@2|Bacteria,2IFFI@201174|Actinobacteria,4GE7V@85026|Gordoniaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_1523472_10	1298863.AUEP01000016_gene4282	1.3e-33	140.0	COG0640@1|root,COG0640@2|Bacteria,2ISNZ@201174|Actinobacteria,4DVG0@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158463_k127_1523472_8	710696.Intca_1013	3.27e-38	166.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4FFFG@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_1523472_2	1298863.AUEP01000003_gene3102	1.271e-135	449.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4DRU4@85009|Propionibacteriales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihA	-	3.2.2.1	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158463_k127_1523472_3	1172188.KB911825_gene3674	2.058e-101	343.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4FFN2@85021|Intrasporangiaceae	201174|Actinobacteria	G	Beta-N-acetylhexosaminidase	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158463_k127_1523472_7	1172188.KB911825_gene3670	2.069e-46	179.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_1523472_9	478801.Ksed_22370	3.231e-35	137.0	COG0640@1|root,COG0640@2|Bacteria,2HF5U@201174|Actinobacteria,1ZX1K@145357|Dermacoccaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158463_k127_1523472_4	478801.Ksed_07500	2.671e-84	281.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,1ZVF7@145357|Dermacoccaceae	201174|Actinobacteria	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158463_k127_1546124_4	1380370.JIBA01000015_gene15	3.245e-38	146.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4FFFK@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158463_k127_1546124_2	1386089.N865_16355	3.662e-40	158.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria,4FHIQ@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	-	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
SRR25158463_k127_1546124_0	656024.FsymDg_0922	7.34e-156	508.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE,Phosphodiest
SRR25158463_k127_1546124_1	1193181.BN10_190010	2.382e-82	280.0	COG0122@1|root,COG0122@2|Bacteria,2I3NS@201174|Actinobacteria,4FJYU@85021|Intrasporangiaceae	201174|Actinobacteria	L	Iron-sulfur cluster assembly protein HesB	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158463_k127_1546124_5	1386089.N865_16365	1.615e-17	91.0	2BK61@1|root,32EJR@2|Bacteria,2HXVG@201174|Actinobacteria,4FHXC@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1546124_3	710696.Intca_2548	6.312e-40	149.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4FET1@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
SRR25158463_k127_1546230_4	272134.KB731324_gene1543	3.759e-64	242.0	COG0222@1|root,COG0222@2|Bacteria,1GBZT@1117|Cyanobacteria,1HEC7@1150|Oscillatoriales	1117|Cyanobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1546230_0	983917.RGE_26660	3.077e-206	696.0	COG1579@1|root,COG1579@2|Bacteria,1NR14@1224|Proteobacteria,2VZ72@28216|Betaproteobacteria,1KN1K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1546230_1	330214.NIDE2960	1.81e-109	375.0	28H5N@1|root,2Z7I8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1546230_5	926564.KI911656_gene1622	1.358e-60	237.0	COG0793@1|root,COG0793@2|Bacteria,2GNJA@201174|Actinobacteria	201174|Actinobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
SRR25158463_k127_1546230_7	644283.Micau_1062	7.369e-28	128.0	COG0640@1|root,COG0640@2|Bacteria,2HA3W@201174|Actinobacteria,4DES5@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158463_k127_1546230_2	1449069.JMLO01000006_gene1050	1.971e-99	340.0	COG0492@1|root,COG2227@1|root,COG0492@2|Bacteria,COG2227@2|Bacteria,2GIXN@201174|Actinobacteria,4FYCP@85025|Nocardiaceae	201174|Actinobacteria	O	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,Pyr_redox_2
SRR25158463_k127_1546230_3	653045.Strvi_5080	5.955e-74	254.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158463_k127_1546230_6	1380354.JIAN01000005_gene2568	1.848e-51	186.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria	201174|Actinobacteria	IQ	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_1555320_8	1123065.ATWL01000020_gene3544	1.89e-70	261.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158463_k127_1555320_2	1132441.KI519454_gene346	2.843e-173	567.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,1W8S6@1268|Micrococcaceae	201174|Actinobacteria	I	PFAM Carboxylesterase	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
SRR25158463_k127_1555320_1	479431.Namu_0113	6.343e-185	596.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4ESCB@85013|Frankiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	dldH5	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158463_k127_1555320_4	710696.Intca_2125	1.281e-145	466.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4FF2R@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.86,2.5.1.88	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	-	R06447,R09244,R09731	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158463_k127_1555320_5	1380370.JIBA01000014_gene1721	7.661e-121	393.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4FE7P@85021|Intrasporangiaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158463_k127_1555320_7	590998.Celf_0415	7.957e-72	248.0	2B34Q@1|root,2ZK49@2|Bacteria,2I2K1@201174|Actinobacteria,4F1YX@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1555320_6	1380370.JIBA01000014_gene1722	2.722e-96	325.0	COG3145@1|root,COG3145@2|Bacteria,2GNBD@201174|Actinobacteria,4FFUM@85021|Intrasporangiaceae	201174|Actinobacteria	L	Alkylated DNA repair protein	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
SRR25158463_k127_1555320_0	1298863.AUEP01000003_gene2871	1.541e-196	621.0	COG0493@1|root,COG0493@2|Bacteria,2I57P@201174|Actinobacteria,4DP3X@85009|Propionibacteriales	201174|Actinobacteria	E	'glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158463_k127_1555320_9	1122138.AQUZ01000015_gene6844	6.453e-60	228.0	COG2706@1|root,COG2706@2|Bacteria,2GNMK@201174|Actinobacteria,4DRMK@85009|Propionibacteriales	201174|Actinobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
SRR25158463_k127_1555320_3	1386089.N865_17030	1.389e-165	526.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4FFR9@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158463_k127_1555829_3	105425.BBPL01000012_gene1864	1.42e-61	223.0	COG0584@1|root,COG0584@2|Bacteria,2GMMS@201174|Actinobacteria,2NI2R@228398|Streptacidiphilus	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158463_k127_1555829_2	1385518.N798_03360	4.178e-63	221.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4FGR5@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_1555829_4	1122138.AQUZ01000036_gene5441	9.158e-57	209.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,4DQTU@85009|Propionibacteriales	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
SRR25158463_k127_1555829_0	1386089.N865_03275	6.53e-246	789.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4FIRB@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158463_k127_1555829_1	675635.Psed_1649	3.358e-84	287.0	COG1357@1|root,COG1357@2|Bacteria,2GM3W@201174|Actinobacteria,4E1I8@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Pentapeptide repeats (8 copies)	yybG	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158463_k127_1555829_5	296591.Bpro_2383	5.483e-49	181.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VXVS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_1555829_6	66897.DJ64_02045	9.315e-10	62.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	bar	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158463_k127_1562387_3	710696.Intca_1644	1.756e-59	210.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4FFMF@85021|Intrasporangiaceae	201174|Actinobacteria	E	glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158463_k127_1562387_1	1386089.N865_00740	1.397e-125	434.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4FFGE@85021|Intrasporangiaceae	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158463_k127_1562387_2	710696.Intca_1642	7.498e-97	345.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4FEEI@85021|Intrasporangiaceae	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158463_k127_1562387_0	1386089.N865_00750	5.308e-226	712.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4FF8X@85021|Intrasporangiaceae	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
SRR25158463_k127_1562387_4	1089455.MOPEL_029_01590	1.806e-55	198.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4F64Z@85018|Dermatophilaceae	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158463_k127_1580594_5	1179773.BN6_76470	0.00014	49.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4E4CZ@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158463_k127_1580594_2	1380370.JIBA01000019_gene1108	2.658e-161	516.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4FF8I@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Belongs to the cytochrome P450 family	cyp20	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
SRR25158463_k127_1580594_4	1385519.N801_00430	3.561e-39	149.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria,4FJJ8@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1580594_3	710696.Intca_1463	9.233e-145	467.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4FG7D@85021|Intrasporangiaceae	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158463_k127_1580594_0	710696.Intca_1464	2.942e-170	558.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4FFFY@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158463_k127_1580594_1	367299.JOEE01000001_gene1986	2.047e-169	536.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4FEEA@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158463_k127_1595396_0	1132441.KI519454_gene1109	0.0	1119.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,1W8N9@1268|Micrococcaceae	201174|Actinobacteria	G	Beta galactosidase small chain	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158463_k127_1595396_3	1132441.KI519454_gene1864	2.057e-87	297.0	COG0667@1|root,COG0667@2|Bacteria,2IA5G@201174|Actinobacteria	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SRR25158463_k127_1595396_4	1120950.KB892757_gene6411	2.992e-86	292.0	COG1028@1|root,COG1028@2|Bacteria,2GKW9@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_1595396_8	1120950.KB892757_gene6410	5.59e-40	152.0	COG0599@1|root,COG0599@2|Bacteria,2HFD1@201174|Actinobacteria,4DVHT@85009|Propionibacteriales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158463_k127_1595396_6	1463881.KL591008_gene2117	1.731e-42	161.0	COG4226@1|root,COG4226@2|Bacteria,2IKXB@201174|Actinobacteria	201174|Actinobacteria	S	protein encoded in hypervariable junctions of pilus gene clusters	-	-	-	-	-	-	-	-	-	-	-	-	HicB
SRR25158463_k127_1595396_5	649831.L083_4265	2.576e-43	175.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4DDXR@85008|Micromonosporales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158463_k127_1595396_1	2002.JOEQ01000001_gene4873	1.289e-127	427.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EHCG@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_1595396_2	1206729.BAFZ01000119_gene2851	5.405e-122	411.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4FW2N@85025|Nocardiaceae	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158463_k127_1595396_7	1120949.KB903358_gene5307	1.273e-41	163.0	COG0726@1|root,COG0726@2|Bacteria,2IH37@201174|Actinobacteria	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158463_k127_1595396_9	2074.JNYD01000007_gene2072	5.244e-23	99.0	2A84P@1|root,30X5E@2|Bacteria,2IN6P@201174|Actinobacteria,4EBJJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1612707_3	710696.Intca_0196	6.094e-63	218.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4FF6B@85021|Intrasporangiaceae	201174|Actinobacteria	S	HAD family hydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158463_k127_1612707_1	1172188.KB911822_gene969	4.558e-114	374.0	COG0566@1|root,COG0566@2|Bacteria,2GP9S@201174|Actinobacteria,4FEGY@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158463_k127_1612707_2	367299.JOEE01000002_gene2429	3.706e-111	361.0	COG0346@1|root,COG0346@2|Bacteria,2I5X0@201174|Actinobacteria,4FFUT@85021|Intrasporangiaceae	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
SRR25158463_k127_1612707_4	35754.JNYJ01000081_gene4188	2.434e-32	130.0	COG3801@1|root,COG3801@2|Bacteria,2IHP4@201174|Actinobacteria,4DDVV@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158463_k127_1612707_0	367299.JOEE01000002_gene2423	7.789e-222	692.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4FE78@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes two discrete reactions in the de novo synthesis of purines the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
SRR25158463_k127_1618678_6	1380370.JIBA01000014_gene2070	3.106e-56	199.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4FEQF@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158463_k127_1618678_0	1386089.N865_04690	7.357e-244	767.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4FFVK@85021|Intrasporangiaceae	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
SRR25158463_k127_1618678_3	1386089.N865_04695	5.201e-153	497.0	COG4191@1|root,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria,4FFVM@85021|Intrasporangiaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,cNMP_binding
SRR25158463_k127_1618678_5	1172188.KB911821_gene1594	1.362e-85	289.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4FGBY@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158463_k127_1618678_4	313589.JNB_07069	6.241e-100	336.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4FE7F@85021|Intrasporangiaceae	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
SRR25158463_k127_1618678_2	1386089.N865_06875	2.038e-173	550.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4FEY0@85021|Intrasporangiaceae	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158463_k127_1618678_7	367299.JOEE01000004_gene989	9.88e-35	135.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4FHA9@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158463_k127_1618678_1	188626.HMPREF0321_2745	3.69e-205	649.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,1ZVB6@145357|Dermacoccaceae	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158463_k127_164729_4	1380370.JIBA01000010_gene2394	8.107e-59	212.0	COG4923@1|root,COG4923@2|Bacteria,2IJP8@201174|Actinobacteria,4FF1N@85021|Intrasporangiaceae	201174|Actinobacteria	K	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
SRR25158463_k127_164729_0	1089544.KB912942_gene966	3.364e-190	603.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4DZ38@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
SRR25158463_k127_164729_1	1032480.MLP_13180	1.941e-167	566.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4DN27@85009|Propionibacteriales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158463_k127_164729_6	1040989.AWZU01000008_gene3713	2.777e-09	67.0	COG0517@1|root,COG0517@2|Bacteria,1NY5H@1224|Proteobacteria,2U1GG@28211|Alphaproteobacteria,3JTNC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	BON domain	MA20_38110	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158463_k127_164729_3	1246995.AFR_00945	1.058e-93	317.0	COG0596@1|root,COG0596@2|Bacteria,2I9SQ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158463_k127_164729_2	1120960.ATXG01000001_gene596	7.649e-106	360.0	COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4FMI2@85023|Microbacteriaceae	201174|Actinobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_164729_5	1343740.M271_45115	1.236e-31	124.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158463_k127_16559_5	1210046.B277_13189	2.341e-82	276.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4FE4H@85021|Intrasporangiaceae	201174|Actinobacteria	S	permease	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158463_k127_16559_11	760192.Halhy_5460	1.467e-10	68.0	COG1917@1|root,COG1917@2|Bacteria,4NUTA@976|Bacteroidetes,1IZA5@117747|Sphingobacteriia	976|Bacteroidetes	S	SPTR Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_16559_8	1385521.N803_04140	7.166e-49	178.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4FGV1@85021|Intrasporangiaceae	201174|Actinobacteria	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_16559_1	1385521.N803_04145	7.082e-186	593.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4FF3R@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	pimH	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158463_k127_16559_0	710696.Intca_0746	6.142e-196	617.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4FEJI@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158463_k127_16559_6	1283283.ATXA01000005_gene2123	3.576e-81	279.0	2DBZA@1|root,2ZC0A@2|Bacteria,2I884@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_16559_7	1380370.JIBA01000019_gene962	4.816e-51	194.0	COG1357@1|root,COG1357@2|Bacteria,2GK0E@201174|Actinobacteria,4FFUA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158463_k127_16559_10	1089455.MOPEL_091_00180	1.619e-14	80.0	2EQ5R@1|root,33HS1@2|Bacteria,2GRI3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_16559_4	1385519.N801_04505	8.529e-99	327.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4FEM1@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2607	PNP_phzG_C,Putative_PNPOx
SRR25158463_k127_16559_2	1172188.KB911829_gene4404	5.963e-133	436.0	COG0477@1|root,COG2814@2|Bacteria,2H0CW@201174|Actinobacteria,4FEGR@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_16559_3	1385521.N803_04190	1.475e-112	366.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4FFDP@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158463_k127_16559_9	1386089.N865_21295	9.673e-44	168.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4FH6S@85021|Intrasporangiaceae	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,NLPC_P60
SRR25158463_k127_1656372_4	66897.DJ64_10315	1.563e-85	295.0	COG2230@1|root,COG2230@2|Bacteria,2GKD3@201174|Actinobacteria	201174|Actinobacteria	M	SAM dependent carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_7
SRR25158463_k127_1656372_8	1385521.N803_16885	1.362e-19	89.0	2DEFJ@1|root,2ZMTQ@2|Bacteria,2HXW2@201174|Actinobacteria,4FI1N@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1656372_6	1121385.AQXW01000003_gene436	2.304e-51	191.0	COG0776@1|root,COG0776@2|Bacteria,2GV0M@201174|Actinobacteria,1ZW6T@145357|Dermacoccaceae	201174|Actinobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158463_k127_1656372_3	1386089.N865_13780	2.896e-101	336.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4FE44@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2987c	Aconitase_C
SRR25158463_k127_1656372_0	367299.JOEE01000004_gene1130	6.219e-270	835.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4FE5P@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158463_k127_1656372_1	1386089.N865_13790	1.55e-135	436.0	COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4FEDT@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	ltbR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158463_k127_1656372_2	767029.HMPREF9154_1763	2.416e-121	401.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DP9F@85009|Propionibacteriales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158463_k127_1656372_5	1172188.KB911821_gene1459	5.1e-58	206.0	2DKWS@1|root,30N64@2|Bacteria,2IQR3@201174|Actinobacteria,4FH8S@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR25158463_k127_1656372_7	367299.JOEE01000004_gene1126	3.997e-42	162.0	COG0789@1|root,COG0789@2|Bacteria,2I9B3@201174|Actinobacteria,4FHJJ@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158463_k127_1671100_0	1172188.KB911825_gene3787	6.798e-109	366.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4FEA0@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
SRR25158463_k127_1671100_4	234621.RER_07160	4.327e-49	179.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria,4G1QC@85025|Nocardiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
SRR25158463_k127_1671100_6	1380370.JIBA01000016_gene920	6.441e-28	125.0	2DEPJ@1|root,2ZNR5@2|Bacteria,2HXCV@201174|Actinobacteria,4FG9P@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1671100_2	1184609.KILIM_113_00120	8.749e-64	224.0	COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4F71D@85018|Dermatophilaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158463_k127_1671100_3	1385521.N803_04645	8.167e-60	210.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4FGHH@85021|Intrasporangiaceae	201174|Actinobacteria	H	Molybdenum cofactor synthesis protein	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
SRR25158463_k127_1671100_1	1385521.N803_04650	6.355e-73	249.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4FGBG@85021|Intrasporangiaceae	201174|Actinobacteria	H	Molybdenum cofactor biosynthesis protein MoaC	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158463_k127_1671100_5	479435.Kfla_5766	2.719e-40	152.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4DNAW@85009|Propionibacteriales	201174|Actinobacteria	H	MoeA domain protein domain I and II	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158463_k127_1678129_1	710696.Intca_1842	5.923e-130	428.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4FEV5@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158463_k127_1678129_4	1386089.N865_15370	1.147e-43	169.0	2DF72@1|root,32U4U@2|Bacteria,2GIV4@201174|Actinobacteria,4FH6P@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1678129_0	1172188.KB911823_gene614	1.769e-216	713.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4FFTM@85021|Intrasporangiaceae	201174|Actinobacteria	J	Histidine--tRNA ligase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158463_k127_1678129_2	367299.JOEE01000008_gene544	1.653e-102	338.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4FEMC@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158463_k127_1678129_3	1386089.N865_15355	4.734e-71	250.0	COG0652@1|root,COG0652@2|Bacteria,2GN8G@201174|Actinobacteria,4FG3D@85021|Intrasporangiaceae	201174|Actinobacteria	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158463_k127_1678129_5	1123251.ATWM01000002_gene213	2.186e-29	125.0	COG3266@1|root,COG3266@2|Bacteria,2I2EC@201174|Actinobacteria,4FEAY@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
SRR25158463_k127_1688554_3	1385518.N798_06935	3.275e-33	129.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4FGD7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158463_k127_1688554_1	1449353.JQMQ01000005_gene4375	1.822e-122	403.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,2NH6E@228398|Streptacidiphilus	201174|Actinobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
SRR25158463_k127_1688554_2	2045.KR76_15430	1.442e-104	354.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria,4DPRP@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_1688554_0	1380370.JIBA01000016_gene899	1.656e-144	462.0	COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4FF3M@85021|Intrasporangiaceae	201174|Actinobacteria	C	Phosphoenolpyruvate carboxylase	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158463_k127_1697822_2	479431.Namu_5263	4.352e-49	194.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158463_k127_1697822_3	1386089.N865_06520	1.97e-42	156.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4FH6M@85021|Intrasporangiaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158463_k127_1697822_0	710696.Intca_2375	1.765e-260	810.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4FFVV@85021|Intrasporangiaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158463_k127_1697822_1	1386089.N865_06510	7.372e-208	659.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4FE8G@85021|Intrasporangiaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158463_k127_1702758_0	1172188.KB911822_gene902	2.465e-219	685.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria,4FEHU@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158463_k127_1702758_4	1386089.N865_00525	2.573e-115	381.0	COG3718@1|root,COG3718@2|Bacteria,2GM8S@201174|Actinobacteria,4FFG9@85021|Intrasporangiaceae	201174|Actinobacteria	G	5-deoxyglucuronate isomerase	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158463_k127_1702758_3	1172188.KB911822_gene900	6.751e-141	470.0	COG1830@1|root,COG1830@2|Bacteria,2GKTN@201174|Actinobacteria,4FF3U@85021|Intrasporangiaceae	201174|Actinobacteria	G	Deoxyribose-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1702758_2	1172188.KB911822_gene899	2.797e-154	510.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria,4FEUX@85021|Intrasporangiaceae	201174|Actinobacteria	G	Sugar kinase	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_1702758_1	1172188.KB911822_gene898	1.767e-172	546.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4FFPX@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158463_k127_1702758_5	1386089.N865_19160	1.135e-98	329.0	2DBMF@1|root,2Z9YG@2|Bacteria,2HX61@201174|Actinobacteria,4FF09@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1702758_7	1068978.AMETH_5451	3.665e-56	218.0	COG0368@1|root,COG0368@2|Bacteria,2GKM4@201174|Actinobacteria,4E2M6@85010|Pseudonocardiales	201174|Actinobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158463_k127_1702758_6	1172188.KB911827_gene4323	5.983e-60	213.0	COG2087@1|root,COG2087@2|Bacteria,2GM8Q@201174|Actinobacteria,4FGDE@85021|Intrasporangiaceae	201174|Actinobacteria	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,Lactamase_B_2
SRR25158463_k127_1702758_8	561175.KB894107_gene5502	2.652e-46	173.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4EG5Z@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,DBI_PRT,Nitroreductase
SRR25158463_k127_1719971_0	1032480.MLP_06240	0.0	1011.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4DP6B@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158463_k127_1719971_7	1172188.KB911820_gene2798	8.749e-61	221.0	COG2606@1|root,COG2606@2|Bacteria,2IIIW@201174|Actinobacteria,4FGY4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158463_k127_1719971_2	1386089.N865_13590	1.31e-174	556.0	COG0624@1|root,COG0624@2|Bacteria,2GJDE@201174|Actinobacteria,4FEEY@85021|Intrasporangiaceae	201174|Actinobacteria	E	Allantoate amidohydrolase	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_1719971_4	710696.Intca_3335	9.929e-160	526.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4FG5E@85021|Intrasporangiaceae	201174|Actinobacteria	F	N-formimino-L-glutamate deiminase	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158463_k127_1719971_3	1385518.N798_01590	9.73e-166	545.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4FEDI@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158463_k127_1719971_9	1449976.KALB_2914	7.374e-21	105.0	COG3758@1|root,COG3758@2|Bacteria,2I1WF@201174|Actinobacteria,4EDKM@85010|Pseudonocardiales	201174|Actinobacteria	S	HutD	-	-	-	ko:K09975	-	-	-	-	ko00000	-	-	-	HutD
SRR25158463_k127_1719971_5	479431.Namu_1652	1.168e-146	467.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4ET1X@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_1719971_1	1298863.AUEP01000006_gene3468	8.788e-269	868.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4DX0S@85009|Propionibacteriales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158463_k127_1719971_8	1298863.AUEP01000006_gene3467	2.114e-59	220.0	COG3945@1|root,COG3945@2|Bacteria,2IKF0@201174|Actinobacteria	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158463_k127_1719971_6	367299.JOEE01000007_gene176	3.494e-83	286.0	COG0702@1|root,COG0702@2|Bacteria,2IJ9N@201174|Actinobacteria,4FIFC@85021|Intrasporangiaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158463_k127_1719971_10	1298863.AUEP01000014_gene1697	2.779e-14	77.0	2DR0Y@1|root,339QH@2|Bacteria,2GSDX@201174|Actinobacteria,4DS2E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
SRR25158463_k127_1719971_11	1386089.N865_13535	5.563e-06	50.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4FEYK@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter (Permease)	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
SRR25158463_k127_1748511_1	1172188.KB911821_gene1846	2.938e-125	406.0	COG2070@1|root,COG2070@2|Bacteria,2GKV4@201174|Actinobacteria,4FEQH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Nitronate monooxygenase	yrpB	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
SRR25158463_k127_1748511_0	1380370.JIBA01000015_gene130	0.0	1027.0	COG0488@1|root,COG0488@2|Bacteria,2GMUD@201174|Actinobacteria,4FE37@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158463_k127_1748511_2	1172188.KB911821_gene1848	1.841e-68	239.0	2AYWQ@1|root,31R2E@2|Bacteria,2IT1D@201174|Actinobacteria,4FHCC@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1748511_3	1172188.KB911821_gene1849	3.152e-61	223.0	2DSJP@1|root,33GEW@2|Bacteria,2IIPW@201174|Actinobacteria,4FGR9@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DcrB
SRR25158463_k127_1748511_4	1323361.JPOC01000036_gene4092	7.223e-36	143.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4FUAS@85025|Nocardiaceae	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158463_k127_1753184_8	1386089.N865_03860	1.646e-96	317.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4FFCI@85021|Intrasporangiaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158463_k127_1753184_3	1386089.N865_03865	2.069e-190	601.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4FF7C@85021|Intrasporangiaceae	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158463_k127_1753184_7	710696.Intca_2723	2.196e-98	328.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4FFMA@85021|Intrasporangiaceae	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158463_k127_1753184_15	1385520.N802_07860	5.239e-24	119.0	COG3860@1|root,COG3860@2|Bacteria,2HXJ0@201174|Actinobacteria,4FH44@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087
SRR25158463_k127_1753184_12	1206744.BAGL01000027_gene7449	1.028e-48	179.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4G0FQ@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR25158463_k127_1753184_16	1386089.N865_04850	6.08e-20	91.0	2DRVB@1|root,33D80@2|Bacteria,2HXVK@201174|Actinobacteria,4FHXY@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1753184_5	1172188.KB911821_gene1947	3.104e-127	425.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4FFYK@85021|Intrasporangiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158463_k127_1753184_2	37919.EP51_19980	1.626e-220	699.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FX1G@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158463_k127_1753184_1	1386089.N865_04835	2.147e-244	786.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4FG4V@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158463_k127_1753184_9	675635.Psed_4268	3.492e-62	218.0	COG4803@1|root,COG4803@2|Bacteria,2IHYU@201174|Actinobacteria,4E3RP@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158463_k127_1753184_6	313589.JNB_08074	3.567e-118	391.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4FES4@85021|Intrasporangiaceae	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158463_k127_1753184_14	1041139.KB902591_gene520	1.885e-27	121.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UBYC@28211|Alphaproteobacteria,4BC19@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158463_k127_1753184_10	1122609.AUGT01000024_gene360	1.312e-60	217.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Cupin_2
SRR25158463_k127_1753184_11	1122609.AUGT01000024_gene359	2.778e-50	190.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,4DSE4@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158463_k127_1753184_0	710696.Intca_2718	1.056e-313	967.0	COG0488@1|root,COG0488@2|Bacteria,2GMUD@201174|Actinobacteria,4FE37@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158463_k127_1753184_4	2074.JNYD01000001_gene6174	5.641e-139	447.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E4JX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_1753184_13	981369.JQMJ01000004_gene3875	1.05e-28	121.0	COG1309@1|root,COG1309@2|Bacteria,2H2H2@201174|Actinobacteria,2NI4Q@228398|Streptacidiphilus	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158463_k127_1758263_6	1172188.KB911825_gene3768	0.0009645	43.0	COG3832@1|root,COG3832@2|Bacteria,2IKRU@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_1758263_3	1206732.BAGD01000118_gene5272	1.252e-66	237.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria,4G2W4@85025|Nocardiaceae	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158463_k127_1758263_2	1150398.JIBJ01000002_gene1165	1.05e-110	366.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,1WBK1@1268|Micrococcaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158463_k127_1758263_4	1380393.JHVP01000006_gene3940	6.27e-65	228.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4EV0P@85013|Frankiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_1758263_0	1386089.N865_10645	2.054e-142	457.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4FEQR@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158463_k127_1758263_5	1386089.N865_10650	3.104e-34	141.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4FH9F@85021|Intrasporangiaceae	201174|Actinobacteria	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158463_k127_1758263_1	1385520.N802_12445	6.191e-119	400.0	COG1316@1|root,COG1316@2|Bacteria,2GM55@201174|Actinobacteria,4FEYR@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158463_k127_1762184_12	1385518.N798_06980	0.0001959	47.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4FHI9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_1762184_9	313589.JNB_03275	4.578e-24	102.0	2E3SR@1|root,32YQ8@2|Bacteria,2GQKG@201174|Actinobacteria,4FHN6@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1762184_10	710696.Intca_1721	3.26e-21	96.0	2EGIC@1|root,33AAH@2|Bacteria,2GQ88@201174|Actinobacteria,4FHIH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3099)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3099
SRR25158463_k127_1762184_6	1306174.JODP01000004_gene969	2.203e-67	243.0	COG2220@1|root,COG2220@2|Bacteria,2GN98@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158463_k127_1762184_3	1380354.JIAN01000007_gene109	4.783e-185	601.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4F13B@85016|Cellulomonadaceae	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
SRR25158463_k127_1762184_5	1172188.KB911823_gene475	3.387e-114	372.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4FF2A@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_1762184_4	1386089.N865_08025	8.823e-146	465.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4FEA4@85021|Intrasporangiaceae	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208,ko:K11611	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_1762184_2	1386089.N865_08020	7.605e-271	864.0	COG0769@1|root,COG0769@2|Bacteria,2GME3@201174|Actinobacteria,4FF9P@85021|Intrasporangiaceae	201174|Actinobacteria	M	Tetratrico peptide repeat	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,TPR_5
SRR25158463_k127_1762184_8	1137269.AZWL01000024_gene1046	1.633e-47	175.0	COG0748@1|root,COG0748@2|Bacteria,2INF5@201174|Actinobacteria	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_1762184_7	33876.JNXY01000003_gene32	6.202e-58	208.0	COG1309@1|root,COG1309@2|Bacteria,2INRU@201174|Actinobacteria,4DHA8@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_1762184_1	1713.JOFV01000006_gene2713	8.878e-274	883.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4F0GU@85016|Cellulomonadaceae	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158463_k127_1762184_0	1380370.JIBA01000013_gene1499	0.0	1547.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,4FESF@85021|Intrasporangiaceae	201174|Actinobacteria	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158463_k127_1762184_11	1172188.KB911823_gene479	8.836e-21	93.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,4FEKB@85021|Intrasporangiaceae	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158463_k127_1791025_1	1386089.N865_18010	1.826e-294	906.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria,4FFMS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158463_k127_1791025_7	1298863.AUEP01000006_gene3354	2.624e-106	368.0	2AIWY@1|root,319EK@2|Bacteria,2I9P9@201174|Actinobacteria,4DNCC@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1791025_9	1283287.KB822575_gene665	4.896e-97	322.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DTYA@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_1791025_2	1385521.N803_06205	5.562e-262	821.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4FEHR@85021|Intrasporangiaceae	201174|Actinobacteria	I	AMP-dependent synthetase	fadD11_1	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158463_k127_1791025_8	743718.Isova_0339	4.06e-102	340.0	COG0697@1|root,COG0697@2|Bacteria,2H1HG@201174|Actinobacteria,4F3ZB@85017|Promicromonosporaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
SRR25158463_k127_1791025_10	367299.JOEE01000001_gene2170	2.619e-89	303.0	COG0583@1|root,COG0583@2|Bacteria,2GM99@201174|Actinobacteria,4FGCC@85021|Intrasporangiaceae	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158463_k127_1791025_5	1172188.KB911821_gene1318	6.177e-138	449.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4FFT3@85021|Intrasporangiaceae	201174|Actinobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158463_k127_1791025_4	1380370.JIBA01000014_gene1823	1.794e-138	447.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4FEHC@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158463_k127_1791025_11	1171373.PACID_28540	4.947e-88	301.0	COG0863@1|root,COG0863@2|Bacteria,2I5QP@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1791025_6	1385519.N801_19005	2.14e-106	357.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4FEDD@85021|Intrasporangiaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158463_k127_1791025_12	1386089.N865_17980	9.194e-63	225.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4FGS0@85021|Intrasporangiaceae	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158463_k127_1791025_0	710696.Intca_2225	0.0	1282.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4FEB5@85021|Intrasporangiaceae	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158463_k127_1791025_13	710696.Intca_2226	4.986e-26	115.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,4FHW1@85021|Intrasporangiaceae	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158463_k127_1791025_3	710696.Intca_2227	8.755e-143	454.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4FECC@85021|Intrasporangiaceae	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158463_k127_1802984_0	1210046.B277_08929	7.337e-165	524.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4FEPC@85021|Intrasporangiaceae	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158463_k127_1802984_1	1121017.AUFG01000009_gene1548	1.744e-126	412.0	COG0494@1|root,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4FF7Y@85021|Intrasporangiaceae	201174|Actinobacteria	L	phosphohistidine phosphatase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158463_k127_1803375_6	243231.GSU1755	1.374e-39	152.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158463_k127_1803375_1	1386089.N865_00940	2.147e-117	392.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4FFRF@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158463_k127_1803375_0	312284.A20C1_12229	3.261e-136	456.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,3UWXY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CH	FAD binding domain	mhpA	-	1.14.13.127,1.14.13.219,1.14.13.220	ko:K05712,ko:K16022,ko:K20943,ko:K20944	ko00360,ko00362,ko01051,ko01052,ko01120,ko01220,map00360,map00362,map01051,map01052,map01120,map01220	M00545	R05249,R06786,R06787,R11347	RC00046,RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158463_k127_1803375_4	1125971.ASJB01000045_gene3944	2.951e-43	175.0	COG0454@1|root,COG0454@2|Bacteria,2I32X@201174|Actinobacteria,4E4IA@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158463_k127_1803375_5	1306174.JODP01000013_gene7496	9.887e-40	158.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1803375_2	1386089.N865_00925	2.922e-90	308.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4FG6C@85021|Intrasporangiaceae	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158463_k127_1803375_7	710696.Intca_1610	7.464e-37	151.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4FHAE@85021|Intrasporangiaceae	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158463_k127_1803375_3	1385519.N801_16000	1.09e-88	295.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4FEEJ@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158463_k127_1864375_0	1380370.JIBA01000015_gene172	1.987e-243	754.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4FFNY@85021|Intrasporangiaceae	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158463_k127_1864375_2	749927.AMED_3774	4.055e-113	376.0	COG2021@1|root,COG2197@1|root,COG2021@2|Bacteria,COG2197@2|Bacteria,2GN4Z@201174|Actinobacteria,4EBFJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,GerE
SRR25158463_k127_1864375_3	1385520.N802_12255	2.605e-59	213.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4FHAM@85021|Intrasporangiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158463_k127_1864375_1	1172188.KB911821_gene1896	6.974e-186	601.0	COG1362@1|root,COG1362@2|Bacteria,2GKW4@201174|Actinobacteria,4FE9J@85021|Intrasporangiaceae	201174|Actinobacteria	E	Aminopeptidase I zinc metalloprotease (M18)	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
SRR25158463_k127_1864375_4	1120949.KB903328_gene9003	2.9e-46	174.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4DE3M@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
SRR25158463_k127_1864375_5	1184609.KILIM_003_01270	8.682e-22	98.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4F6V2@85018|Dermatophilaceae	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158463_k127_1867873_1	33898.JRHJ01000055_gene5723	3.795e-220	696.0	COG1132@1|root,COG1132@2|Bacteria,2GJTA@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_1867873_0	1283287.KB822575_gene219	2.027e-305	969.0	COG3387@1|root,COG4945@1|root,COG3387@2|Bacteria,COG4945@2|Bacteria,2HCB8@201174|Actinobacteria	201174|Actinobacteria	G	Glucodextranase, domain N	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	CBM_20,Glucodextran_N,Glyco_hydro_15,fn3
SRR25158463_k127_1867873_10	1132441.KI519455_gene2575	1.644e-80	284.0	COG1940@1|root,COG1940@2|Bacteria,2GNFJ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,ROK
SRR25158463_k127_1867873_2	479431.Namu_1749	2.309e-219	697.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,4EWY7@85013|Frankiales	201174|Actinobacteria	M	Phosphoesterase family	acpA	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SRR25158463_k127_1867873_11	1298863.AUEP01000008_gene1214	1.994e-69	243.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4DR7C@85009|Propionibacteriales	201174|Actinobacteria	F	Peptidase C26	-	-	6.3.5.2	ko:K01951,ko:K07065	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRR25158463_k127_1867873_7	1137269.AZWL01000006_gene6727	1.816e-95	320.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158463_k127_1867873_9	367299.JOEE01000006_gene702	1.637e-80	272.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4FGGE@85021|Intrasporangiaceae	201174|Actinobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3581c	YgbB
SRR25158463_k127_1867873_5	1172188.KB911830_gene3833	1.078e-101	337.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4FFZ9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158463_k127_1867873_12	1386089.N865_02175	3.488e-65	230.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4FGMU@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158463_k127_1867873_8	710696.Intca_2927	2.11e-87	291.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4FE53@85021|Intrasporangiaceae	201174|Actinobacteria	K	CarD family transcriptional regulator	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158463_k127_1867873_13	1193181.BN10_890005	6.301e-14	81.0	2E56G@1|root,32ZZ6@2|Bacteria,2GR3Y@201174|Actinobacteria,4FHTB@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1867873_4	710696.Intca_2929	3.97e-125	424.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4FEUK@85021|Intrasporangiaceae	201174|Actinobacteria	T	XRE family transcriptional regulator	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_1867873_3	1172188.KB911830_gene3838	5.169e-147	475.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4FEMZ@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	senX3	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SRR25158463_k127_1867873_6	1172188.KB911830_gene3839	3.467e-98	332.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4FEIT@85021|Intrasporangiaceae	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158463_k127_1891916_6	714083.JH370377_gene1284	4.987e-47	174.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4FRNZ@85023|Microbacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	iNJ661.Rv1928c	adh_short_C2
SRR25158463_k127_1891916_3	58123.JOFJ01000007_gene750	1.067e-72	253.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria,4EJAX@85012|Streptosporangiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158463_k127_1891916_0	1385521.N803_08825	0.0	1319.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4FEBK@85021|Intrasporangiaceae	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158463_k127_1891916_7	1386089.N865_00685	2.663e-36	146.0	COG0454@1|root,COG0456@2|Bacteria,2II5Y@201174|Actinobacteria,4FGGR@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_1891916_1	313589.JNB_03790	1.635e-113	371.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria,4FESJ@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
SRR25158463_k127_1891916_2	1184609.KILIM_005_00170	1.111e-91	306.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4F6IJ@85018|Dermatophilaceae	201174|Actinobacteria	K	ANTAR	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158463_k127_1891916_5	710696.Intca_3559	5.549e-65	235.0	28NWQ@1|root,2ZBUI@2|Bacteria,2IGY4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1891916_8	1210046.B277_11890	9.705e-06	49.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4FEJM@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the formation of phosphoenolpyruvate from pyruvate	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158463_k127_1891916_4	1385520.N802_17100	5.036e-68	233.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4FEJM@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the formation of phosphoenolpyruvate from pyruvate	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158463_k127_1892521_10	1386089.N865_17385	5.673e-59	208.0	COG2151@1|root,COG2151@2|Bacteria,2II4H@201174|Actinobacteria,4FGVA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Iron-sulfur cluster assembly protein	paaJ	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158463_k127_1892521_1	1386089.N865_17380	3.977e-174	561.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4FF97@85021|Intrasporangiaceae	201174|Actinobacteria	C	phenylacetic acid degradation	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,FA_desaturase,Fer2,NAD_binding_1
SRR25158463_k127_1892521_14	1380370.JIBA01000011_gene3074	1.33e-06	54.0	2EHFT@1|root,33B7P@2|Bacteria,2GYTG@201174|Actinobacteria,4FI4W@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1892521_8	1386089.N865_04600	4.997e-67	236.0	COG4702@1|root,COG4702@2|Bacteria,2IFGG@201174|Actinobacteria,4FGN9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the UPF0303 family	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158463_k127_1892521_6	367299.JOEE01000003_gene2681	5.374e-69	239.0	COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria,4FGNT@85021|Intrasporangiaceae	201174|Actinobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1,NUDIX
SRR25158463_k127_1892521_3	1385518.N798_15750	2.302e-151	482.0	COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4FFQE@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
SRR25158463_k127_1892521_4	1385518.N798_15755	3.104e-119	390.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4FFB3@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158463_k127_1892521_0	1386089.N865_17345	3.052e-302	945.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4FFG7@85021|Intrasporangiaceae	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158463_k127_1892521_9	313589.JNB_01225	3.578e-62	225.0	COG3021@1|root,COG3021@2|Bacteria,2GKXC@201174|Actinobacteria,4FH37@85021|Intrasporangiaceae	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158463_k127_1892521_12	1380347.JNII01000005_gene3520	6.486e-30	124.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158463_k127_1892521_11	1380347.JNII01000005_gene3519	6.899e-48	181.0	COG3832@1|root,COG3832@2|Bacteria,2GQIZ@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_1892521_7	1304876.AZVC01000014_gene2538	5.467e-68	240.0	2AKGE@1|root,31B89@2|Bacteria,2IN2E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1892521_13	1283283.ATXA01000026_gene3694	1.805e-18	92.0	2DDXF@1|root,2ZJPY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1892521_2	1172188.KB911821_gene1273	2.487e-168	552.0	COG0520@1|root,COG0520@2|Bacteria,2GMIC@201174|Actinobacteria,4FFF7@85021|Intrasporangiaceae	201174|Actinobacteria	E	Cysteine desulfurase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158463_k127_1892521_5	1172188.KB911821_gene1272	4.32e-85	287.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4FEFA@85021|Intrasporangiaceae	201174|Actinobacteria	D	Cell division protein FtsK	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158463_k127_1906625_9	590998.Celf_0034	2.721e-43	164.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4F17R@85016|Cellulomonadaceae	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158463_k127_1906625_7	710696.Intca_0068	4.645e-104	344.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4FEVW@85021|Intrasporangiaceae	201174|Actinobacteria	T	Signal peptide protein	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158463_k127_1906625_1	675635.Psed_6201	6.358e-217	684.0	COG3104@1|root,COG3104@2|Bacteria,2GKB1@201174|Actinobacteria,4DY8M@85010|Pseudonocardiales	201174|Actinobacteria	E	POT family	dtpT	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158463_k127_1906625_6	397278.JOJN01000003_gene2076	3.917e-111	365.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria,4DT41@85009|Propionibacteriales	201174|Actinobacteria	L	Formamidopyrimidine-DNA glycosylase N-terminal domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158463_k127_1906625_2	675635.Psed_6201	4.698e-195	619.0	COG3104@1|root,COG3104@2|Bacteria,2GKB1@201174|Actinobacteria,4DY8M@85010|Pseudonocardiales	201174|Actinobacteria	E	POT family	dtpT	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SRR25158463_k127_1906625_4	1435356.Y013_05540	4.113e-162	523.0	COG2425@1|root,COG2425@2|Bacteria,2GK1P@201174|Actinobacteria,4FX8R@85025|Nocardiaceae	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
SRR25158463_k127_1906625_0	258052.JNYV01000006_gene2643	1.983e-261	844.0	COG1916@1|root,COG1916@2|Bacteria,2H79D@201174|Actinobacteria,2M19Y@2063|Kitasatospora	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1906625_3	1110697.NCAST_33_00260	2.155e-192	614.0	COG0714@1|root,COG0714@2|Bacteria,2GMBP@201174|Actinobacteria,4FV46@85025|Nocardiaceae	201174|Actinobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158463_k127_1906625_8	258052.JNYV01000006_gene2645	1.654e-44	185.0	COG5094@1|root,COG5094@2|Bacteria,2I306@201174|Actinobacteria,2M0FM@2063|Kitasatospora	201174|Actinobacteria	K	RNA polymerase II transcriptional preinitiation complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1906625_5	1112204.GPOL_c01960	5.271e-120	403.0	COG4715@1|root,COG4715@2|Bacteria,2GKC8@201174|Actinobacteria,4GCTA@85026|Gordoniaceae	201174|Actinobacteria	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
SRR25158463_k127_1906625_10	2074.JNYD01000007_gene2072	1.005e-38	148.0	2A84P@1|root,30X5E@2|Bacteria,2IN6P@201174|Actinobacteria,4EBJJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1912922_4	1172188.KB911821_gene2012	5.061e-39	149.0	2D19V@1|root,334ZZ@2|Bacteria,2I39B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1912922_0	1386089.N865_17615	2.603e-135	447.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4FEU8@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158463_k127_1912922_1	1386089.N865_17630	7.501e-131	424.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4FFDC@85021|Intrasporangiaceae	201174|Actinobacteria	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158463_k127_1912922_2	1172188.KB911824_gene3180	4.482e-117	379.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,4FFD8@85021|Intrasporangiaceae	201174|Actinobacteria	I	Succinyl-CoA 3-ketoacid-CoA transferase	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158463_k127_1912922_3	1386089.N865_17620	2.221e-73	263.0	COG0365@1|root,COG0365@2|Bacteria,2I2IW@201174|Actinobacteria,4FGQ9@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158463_k127_1912922_5	1385519.N801_10540	1.62e-35	143.0	COG0438@1|root,COG0438@2|Bacteria,2GX8V@201174|Actinobacteria,4FE76@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_1941511_0	1386089.N865_08875	1.723e-120	392.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4FF4M@85021|Intrasporangiaceae	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158463_k127_1941511_2	2074.JNYD01000022_gene1437	3.276e-57	228.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXJW@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158463_k127_1941511_1	1385519.N801_11710	1.043e-63	229.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	2|Bacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,PAP2
SRR25158463_k127_1950396_12	479431.Namu_2937	2.771e-68	238.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4ERWA@85013|Frankiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR25158463_k127_1950396_15	1172188.KB911821_gene1776	4.369e-54	208.0	2BARS@1|root,3246W@2|Bacteria,2IM0H@201174|Actinobacteria,4FGXD@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1950396_13	1123251.ATWM01000004_gene1863	3.629e-65	237.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,4FIFT@85021|Intrasporangiaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158463_k127_1950396_18	1386089.N865_01940	3.912e-20	96.0	2EP16@1|root,33GN1@2|Bacteria,2HXS6@201174|Actinobacteria,4FHN8@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1950396_16	1386089.N865_01945	1.457e-47	179.0	2BX7X@1|root,32RMD@2|Bacteria,2IKN7@201174|Actinobacteria,4FGRV@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1950396_2	1122138.AQUZ01000009_gene3982	1.832e-168	540.0	COG1653@1|root,COG1653@2|Bacteria,2GMUM@201174|Actinobacteria,4DQ1V@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158463_k127_1950396_3	1122138.AQUZ01000011_gene4891	1.155e-167	536.0	COG0524@1|root,COG0524@2|Bacteria,2GKQP@201174|Actinobacteria,4DPWJ@85009|Propionibacteriales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	scrK	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158463_k127_1950396_17	1386089.N865_08420	1.653e-38	159.0	2FC1J@1|root,3445K@2|Bacteria,2IHT3@201174|Actinobacteria,4FGQ8@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1950396_9	1713.JOFV01000006_gene2826	1.431e-87	308.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4F1TT@85016|Cellulomonadaceae	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158463_k127_1950396_1	1120950.KB892755_gene5906	4.137e-176	575.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DPFN@85009|Propionibacteriales	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158463_k127_1950396_0	1304865.JAGF01000001_gene2402	1.739e-229	730.0	COG1262@1|root,COG1262@2|Bacteria,2H7FI@201174|Actinobacteria,4F1NT@85016|Cellulomonadaceae	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158463_k127_1950396_11	1095772.CAHH01000026_gene2478	7.986e-69	258.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_1950396_10	1095772.CAHH01000026_gene2472	1.344e-81	299.0	COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_1950396_4	935839.JAGJ01000013_gene2845	1.278e-156	506.0	COG1397@1|root,COG1397@2|Bacteria,2HTZA@201174|Actinobacteria,4F5XR@85017|Promicromonosporaceae	201174|Actinobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1950396_5	1068980.ARVW01000001_gene122	7.627e-140	455.0	COG1397@1|root,COG1397@2|Bacteria,2GQGW@201174|Actinobacteria,4E8KP@85010|Pseudonocardiales	201174|Actinobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
SRR25158463_k127_1950396_7	479435.Kfla_4570	3.303e-122	406.0	COG1653@1|root,COG1653@2|Bacteria,2GNE6@201174|Actinobacteria,4DQ52@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
SRR25158463_k127_1950396_8	479435.Kfla_4571	1.191e-95	334.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4DPVY@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158463_k127_1950396_6	1121272.KB903251_gene870	7.58e-124	404.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4DCIU@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158463_k127_1950396_14	1386089.N865_17590	4.679e-56	199.0	COG1846@1|root,COG1846@2|Bacteria,2I3KG@201174|Actinobacteria,4FGP7@85021|Intrasporangiaceae	201174|Actinobacteria	K	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,MarR
SRR25158463_k127_1950396_19	1380370.JIBA01000017_gene2896	3.503e-11	70.0	2BFEQ@1|root,2ZJ91@2|Bacteria,2IQMF@201174|Actinobacteria,4FHH0@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1957259_2	675635.Psed_0690	5.802e-109	366.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria,4ED6V@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158463_k127_1957259_8	1192034.CAP_5114	1.994e-23	113.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SRR25158463_k127_1957259_7	710687.KI912270_gene5241	2.959e-35	138.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,23ARX@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158463_k127_1957259_5	1380370.JIBA01000018_gene472	7.275e-65	225.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4FH0S@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158463_k127_1957259_10	1121106.JQKB01000026_gene4317	1.088e-11	74.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2JPQU@204441|Rhodospirillales	204441|Rhodospirillales	O	DnaJ C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
SRR25158463_k127_1957259_11	1385518.N798_00790	7.036e-10	69.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4FIWV@85021|Intrasporangiaceae	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_1957259_4	1713.JOFV01000008_gene3081	7.929e-84	289.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4F2WC@85016|Cellulomonadaceae	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,PadR
SRR25158463_k127_1957259_6	1476876.JOJO01000002_gene6413	1.37e-53	192.0	COG0346@1|root,COG0346@2|Bacteria,2IFMD@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1957259_12	471856.Jden_0391	9.989e-07	58.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_1957259_9	313589.JNB_02580	1.099e-22	106.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158463_k127_1957259_3	443906.CMM_0181	8.201e-102	350.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4FMAW@85023|Microbacteriaceae	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
SRR25158463_k127_1957259_0	1380370.JIBA01000015_gene171	3.993e-158	505.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FIR9@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_1957259_1	1385520.N802_03010	4.351e-138	446.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4FF6D@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158463_k127_1967679_0	1121952.ATXT01000013_gene2097	0.0	1069.0	COG0174@1|root,COG0174@2|Bacteria,2GMR5@201174|Actinobacteria,4FMP4@85023|Microbacteriaceae	201174|Actinobacteria	E	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
SRR25158463_k127_1967679_1	479432.Sros_5788	6.257e-164	540.0	COG5441@1|root,COG5441@2|Bacteria,2GKDK@201174|Actinobacteria,4EIDD@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
SRR25158463_k127_1967679_2	1095772.CAHH01000021_gene790	1.162e-129	423.0	COG5564@1|root,COG5564@2|Bacteria,2GMW9@201174|Actinobacteria	201174|Actinobacteria	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
SRR25158463_k127_1967679_4	33876.JNXY01000006_gene1229	1.97e-66	229.0	COG0662@1|root,COG0662@2|Bacteria,2IIB8@201174|Actinobacteria	201174|Actinobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_1967679_3	1132441.KI519454_gene1115	1.821e-127	412.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria	201174|Actinobacteria	M	Epimerase dehydratase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158463_k127_1967679_5	1132441.KI519454_gene1109	1.013e-48	176.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,1W8N9@1268|Micrococcaceae	201174|Actinobacteria	G	Beta galactosidase small chain	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158463_k127_1976470_8	1380370.JIBA01000017_gene2997	6.86e-10	66.0	2BMZF@1|root,32GJB@2|Bacteria,2IQ15@201174|Actinobacteria,4FH2T@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1976470_5	471853.Bcav_3721	1.02e-46	172.0	2CEJ1@1|root,347SX@2|Bacteria,2H96E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_1976470_3	494419.ALPM01000015_gene650	2.002e-116	379.0	28JJ5@1|root,2Z9C9@2|Bacteria,2HB8W@201174|Actinobacteria,1WAJT@1268|Micrococcaceae	201174|Actinobacteria	S	infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158463_k127_1976470_7	710687.KI912270_gene718	2.371e-43	168.0	2DS2T@1|root,33E9A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158463_k127_1976470_2	2074.JNYD01000007_gene2103	4.407e-130	424.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4DXBF@85010|Pseudonocardiales	201174|Actinobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158463_k127_1976470_0	479435.Kfla_6322	1.04e-176	572.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DP72@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_1976470_6	1172188.KB911824_gene3312	1.76e-44	176.0	COG1309@1|root,COG1309@2|Bacteria,2GJHD@201174|Actinobacteria,4FG4R@85021|Intrasporangiaceae	201174|Actinobacteria	K	TetR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158463_k127_1976470_4	477641.MODMU_3269	6.192e-105	360.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4EVP5@85013|Frankiales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158463_k127_1976470_1	367299.JOEE01000003_gene2766	1.126e-155	493.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4FE7Q@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158463_k127_2010186_10	710696.Intca_1925	6.433e-21	93.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4FEE6@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158463_k127_2010186_1	1386089.N865_12660	2.28e-177	565.0	COG0683@1|root,COG0683@2|Bacteria,2HZ5Q@201174|Actinobacteria,4FFB4@85021|Intrasporangiaceae	201174|Actinobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158463_k127_2010186_7	1386089.N865_12665	2.086e-95	341.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4FFAP@85021|Intrasporangiaceae	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158463_k127_2010186_6	710696.Intca_1922	1.176e-106	362.0	COG0410@1|root,COG0410@2|Bacteria,2I93D@201174|Actinobacteria,4FETE@85021|Intrasporangiaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158463_k127_2010186_3	1172188.KB911828_gene4069	1.718e-123	422.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4FFV1@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_2010186_2	710696.Intca_1920	2.763e-144	487.0	COG4177@1|root,COG4177@2|Bacteria,2GNZK@201174|Actinobacteria,4FERP@85021|Intrasporangiaceae	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_2010186_4	1172188.KB911828_gene4071	1.404e-114	385.0	COG2267@1|root,COG2267@2|Bacteria,2HX7Q@201174|Actinobacteria,4FFJN@85021|Intrasporangiaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158463_k127_2010186_0	1172188.KB911828_gene4073	8.602e-217	689.0	COG2203@1|root,COG2508@1|root,COG2203@2|Bacteria,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria,4FEER@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_30
SRR25158463_k127_2010186_5	710696.Intca_1917	1.788e-113	371.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,4FFCP@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
SRR25158463_k127_2010186_9	743718.Isova_1561	6.158e-78	273.0	COG0596@1|root,COG0596@2|Bacteria,2I6E7@201174|Actinobacteria,4F4GF@85017|Promicromonosporaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158463_k127_2010186_8	1172188.KB911828_gene4094	8.533e-87	287.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4FEVM@85021|Intrasporangiaceae	201174|Actinobacteria	M	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase,HTH_3
SRR25158463_k127_2025760_10	1172188.KB911826_gene154	2.103e-34	138.0	COG5343@1|root,COG5343@2|Bacteria,2IM7X@201174|Actinobacteria,4FHJ6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
SRR25158463_k127_2025760_7	1172188.KB911826_gene115	4.052e-80	295.0	COG3342@1|root,COG3342@2|Bacteria,2HWBG@201174|Actinobacteria,4FFQ6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
SRR25158463_k127_2025760_0	1386089.N865_19475	1.609e-241	751.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4FFDT@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the class-II DAHP synthase family	aroG	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.5.1.54	ko:K01626,ko:K16019	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01051,map01100,map01110,map01130,map01230,map02024	M00022	R01826,R06591	RC00435,RC01556	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2178c	DAHP_synth_2
SRR25158463_k127_2025760_1	1386089.N865_19470	1.364e-163	520.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4FFGJ@85021|Intrasporangiaceae	201174|Actinobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158463_k127_2025760_8	512565.AMIS_45390	7.699e-49	191.0	COG3801@1|root,COG3801@2|Bacteria,2IHP4@201174|Actinobacteria,4DDVV@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158463_k127_2025760_5	1035308.AQYY01000001_gene1467	1.475e-144	472.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158463_k127_2025760_4	477641.MODMU_1916	1.684e-146	475.0	COG1595@1|root,COG2172@1|root,COG1595@2|Bacteria,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria,4EWC7@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
SRR25158463_k127_2025760_2	1385518.N798_11920	1.259e-149	482.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria,4FG7K@85021|Intrasporangiaceae	201174|Actinobacteria	T	STAS domain	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
SRR25158463_k127_2025760_9	1380356.JNIK01000021_gene4650	3.287e-46	178.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria,4EWR1@85013|Frankiales	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158463_k127_2025760_6	1172188.KB911827_gene4370	1.695e-116	382.0	COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4FF8D@85021|Intrasporangiaceae	201174|Actinobacteria	EG	permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158463_k127_2025760_3	367299.JOEE01000008_gene371	1.648e-149	488.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FEAH@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158463_k127_203575_1	926564.KI911746_gene3570	3.225e-66	228.0	COG3386@1|root,COG3386@2|Bacteria,2GIW1@201174|Actinobacteria	201174|Actinobacteria	G	Strictosidine synthase	gnl	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158463_k127_203575_3	1298880.AUEV01000020_gene651	1.989e-62	229.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158463_k127_203575_8	1157632.AQWQ01000015_gene3395	1.303e-36	157.0	COG3568@1|root,COG3568@2|Bacteria,2H3ST@201174|Actinobacteria	201174|Actinobacteria	G	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158463_k127_203575_7	313589.JNB_16589	1.576e-44	166.0	2DPPR@1|root,332X4@2|Bacteria,2GRGG@201174|Actinobacteria,4FH60@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_203575_2	1386089.N865_04345	1.769e-63	228.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4FGMN@85021|Intrasporangiaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158463_k127_203575_0	1172188.KB911821_gene2041	6.136e-96	325.0	COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria,4FGA5@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158463_k127_203575_4	365528.KB891159_gene5335	1.022e-59	210.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,4EV41@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_203575_5	33876.JNXY01000001_gene5770	3.156e-59	209.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4DEPN@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158463_k127_203575_6	33876.JNXY01000019_gene7671	5.089e-56	198.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4D901@85008|Micromonosporales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL1	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158463_k127_2050851_6	1386089.N865_08320	5.588e-60	208.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4FEK9@85021|Intrasporangiaceae	201174|Actinobacteria	C	COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	cutM	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158463_k127_2050851_5	367299.JOEE01000001_gene2120	1.358e-67	241.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4FEDB@85021|Intrasporangiaceae	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	-	-	-	-	-	-	-	-	-	COXG
SRR25158463_k127_2050851_3	1185876.BN8_02707	2.5e-82	290.0	COG0189@1|root,COG0189@2|Bacteria,4NR9N@976|Bacteroidetes,47QH3@768503|Cytophagia	976|Bacteroidetes	HJ	RimK-like ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158463_k127_2050851_9	114615.BRADO4373	2.464e-09	68.0	2AWE2@1|root,31NA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2050851_0	662479.C440_05987	1.21e-167	550.0	COG1404@1|root,arCOG00702@2157|Archaea	2157|Archaea	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158463_k127_2050851_1	1380370.JIBA01000013_gene1339	5.72e-136	467.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria,4FE4W@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Chloride transporter	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
SRR25158463_k127_2050851_4	68260.JOAY01000001_gene3850	6.141e-82	289.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria	201174|Actinobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158463_k127_2050851_2	1172188.KB911823_gene649	1.78e-105	350.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4FE9F@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Class IV aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158463_k127_2050851_7	1121385.AQXW01000004_gene1098	3.213e-52	188.0	2E4Q9@1|root,32ZIV@2|Bacteria,2II59@201174|Actinobacteria,1ZW8G@145357|Dermacoccaceae	201174|Actinobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158463_k127_2050851_8	1385520.N802_05180	7.74e-44	165.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158463_k127_2050980_4	1172188.KB911820_gene2120	1.394e-09	62.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4FEXC@85021|Intrasporangiaceae	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
SRR25158463_k127_2050980_2	1386089.N865_08665	2.177e-185	597.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria,4FF69@85021|Intrasporangiaceae	201174|Actinobacteria	EH	With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158463_k127_2050980_3	1386089.N865_08670	1.885e-148	475.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4FEUD@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2392	PAPS_reduct
SRR25158463_k127_2050980_0	1172188.KB911820_gene2123	0.0	1026.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4FF1X@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	sir	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016002,GO:0016053,GO:0016491,GO:0016667,GO:0016673,GO:0019344,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158463_k127_2050980_1	1172188.KB911820_gene2133	1.356e-197	629.0	COG1984@1|root,COG2049@1|root,COG1984@2|Bacteria,COG2049@2|Bacteria,2GITH@201174|Actinobacteria,4FGH8@85021|Intrasporangiaceae	201174|Actinobacteria	E	Allophanate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B,CT_C_D
SRR25158463_k127_2051420_3	1121017.AUFG01000013_gene1966	6.56e-64	225.0	COG0770@1|root,COG0770@2|Bacteria,2I2EU@201174|Actinobacteria,4FFSA@85021|Intrasporangiaceae	201174|Actinobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158463_k127_2051420_8	37919.EP51_33485	1.079e-32	134.0	COG3467@1|root,COG3467@2|Bacteria,2I2V6@201174|Actinobacteria,4G3Q5@85025|Nocardiaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158463_k127_2051420_5	1237500.ANBA01000016_gene4412	2.44e-41	162.0	COG3832@1|root,COG3832@2|Bacteria,2IHN6@201174|Actinobacteria,4EPBT@85012|Streptosporangiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_2051420_9	479433.Caci_4480	7.932e-24	107.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158463_k127_2051420_6	1386089.N865_14395	5.958e-41	168.0	COG5649@1|root,COG5649@2|Bacteria	2|Bacteria	E	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158463_k127_2051420_1	110319.CF8_3665	1.614e-85	287.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4DN62@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2051420_4	1043205.AFYF01000024_gene534	2.867e-47	183.0	COG5340@1|root,COG5340@2|Bacteria,2II40@201174|Actinobacteria,4FGPX@85021|Intrasporangiaceae	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158463_k127_2051420_0	1120934.KB894411_gene6711	1.39e-254	793.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4DXUU@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158463_k127_2051420_7	1380370.JIBA01000016_gene765	3.324e-39	159.0	2E65S@1|root,330UF@2|Bacteria,2IMEQ@201174|Actinobacteria,4FH46@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF3817)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3817
SRR25158463_k127_2051420_2	1184609.KILIM_065_00110	1.894e-66	233.0	COG3346@1|root,COG3346@2|Bacteria,2GMGB@201174|Actinobacteria,4F6YW@85018|Dermatophilaceae	201174|Actinobacteria	S	SURF1 family	-	-	-	-	-	-	-	-	-	-	-	-	SURF1
SRR25158463_k127_2052256_0	1120950.KB892788_gene17	0.0	1918.0	COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,2GIZP@201174|Actinobacteria,4DP64@85009|Propionibacteriales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, central region	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
SRR25158463_k127_2052256_4	521096.Tpau_3671	5.083e-45	165.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SRR25158463_k127_2052256_1	1172188.KB911825_gene3741	4.383e-122	404.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4FFAS@85021|Intrasporangiaceae	201174|Actinobacteria	FP	exopolyphosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158463_k127_2052256_2	1380370.JIBA01000016_gene858	2.677e-68	241.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4FGC6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
SRR25158463_k127_2052256_3	1172188.KB911825_gene3743	1.155e-47	181.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4FHRY@85021|Intrasporangiaceae	201174|Actinobacteria	D	Septation ring formation regulator EzrA	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158463_k127_2065157_2	1172188.KB911821_gene1200	1.53e-130	434.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4FFBH@85021|Intrasporangiaceae	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158463_k127_2065157_4	1386089.N865_16990	7.499e-97	324.0	COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4FFIB@85021|Intrasporangiaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	mntB	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SRR25158463_k127_2065157_3	1386089.N865_16985	2.425e-97	327.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4FE83@85021|Intrasporangiaceae	201174|Actinobacteria	P	Belongs to the bacterial solute-binding protein 9 family	scbA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SRR25158463_k127_2065157_5	1172188.KB911821_gene1197	1.659e-21	97.0	2B904@1|root,322AS@2|Bacteria,2IRVZ@201174|Actinobacteria,4FHJP@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2065157_0	367299.JOEE01000009_gene323	1.471e-278	863.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4FEI3@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158463_k127_2065157_6	345341.KUTG_00111	5.215e-08	58.0	COG4941@1|root,COG4978@1|root,COG4941@2|Bacteria,COG4978@2|Bacteria,2GJ36@201174|Actinobacteria,4DYZC@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_2065157_1	1120950.KB892794_gene2344	1.053e-178	572.0	COG2270@1|root,COG2270@2|Bacteria,2GJSA@201174|Actinobacteria,4DTU8@85009|Propionibacteriales	201174|Actinobacteria	S	Major Facilitator Superfamily	cmr	-	-	ko:K18833	-	-	-	-	ko00000,ko01504,ko02000	2.A.1.21.2	-	-	MFS_1
SRR25158463_k127_2075851_2	1385520.N802_08770	1.721e-262	814.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4FF36@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158463_k127_2075851_0	1172188.KB911826_gene10	0.0	1189.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4FF98@85021|Intrasporangiaceae	201174|Actinobacteria	C	Catalyzes the transfer of electrons from NADH to quinone	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158463_k127_2075851_4	1172188.KB911826_gene9	1.127e-216	707.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4FEYT@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
SRR25158463_k127_2075851_15	367299.JOEE01000001_gene2056	4.301e-102	345.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4FFGF@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
SRR25158463_k127_2075851_16	1193181.BN10_460004	2.084e-95	332.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4FFRB@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158463_k127_2075851_21	367299.JOEE01000001_gene2058	7.32e-40	151.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4FGWN@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158463_k127_2075851_1	1121385.AQXW01000004_gene2139	3.034e-308	955.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria	201174|Actinobacteria	CP	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158463_k127_2075851_3	1386089.N865_18505	5.176e-227	735.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4FFDF@85021|Intrasporangiaceae	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase subunit	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158463_k127_2075851_5	710696.Intca_0699	2.621e-212	674.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4FF3X@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158463_k127_2075851_10	1386089.N865_18495	1.354e-149	481.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4FE3E@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158463_k127_2075851_17	1155718.KB891885_gene6366	6.066e-75	259.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria	201174|Actinobacteria	C	PFAM MOSC domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158463_k127_2075851_13	1380370.JIBA01000012_gene3665	1.62e-118	385.0	COG3173@1|root,COG3173@2|Bacteria,2I5KC@201174|Actinobacteria,4FIWC@85021|Intrasporangiaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158463_k127_2075851_18	367299.JOEE01000002_gene2211	1.042e-72	249.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4FGMV@85021|Intrasporangiaceae	201174|Actinobacteria	S	Diguanylate cyclase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158463_k127_2075851_19	266940.Krad_2869	4.535e-45	171.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
SRR25158463_k127_2075851_12	909613.UO65_0185	1.092e-133	434.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4E00P@85010|Pseudonocardiales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158463_k127_2075851_7	330084.JNYZ01000025_gene2650	8.955e-183	581.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DZSE@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_2075851_6	1386089.N865_04525	3.028e-183	577.0	COG1064@1|root,COG1064@2|Bacteria,2GNNY@201174|Actinobacteria,4FFHD@85021|Intrasporangiaceae	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158463_k127_2075851_11	69042.WH5701_10799	5.793e-146	491.0	COG0318@1|root,COG0318@2|Bacteria,1GQE8@1117|Cyanobacteria,1H02N@1129|Synechococcus	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_2075851_14	1172188.KB911829_gene4454	2.701e-117	402.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria,4FERD@85021|Intrasporangiaceae	201174|Actinobacteria	S	EamA-like transporter family	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
SRR25158463_k127_2075851_8	1172188.KB911829_gene4453	2.092e-175	558.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4FEAR@85021|Intrasporangiaceae	201174|Actinobacteria	C	2-oxoacid ferredoxin oxidoreductase subunit beta	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158463_k127_2075851_9	1386089.N865_18460	3.814e-153	487.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4FEQG@85021|Intrasporangiaceae	201174|Actinobacteria	C	ferredoxin oxidoreductase	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158463_k127_208202_2	298653.Franean1_5399	2.402e-111	377.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EUTF@85013|Frankiales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158463_k127_208202_1	1380390.JIAT01000010_gene3951	2.546e-125	415.0	COG3287@1|root,COG3287@2|Bacteria,2GTCE@201174|Actinobacteria	201174|Actinobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158463_k127_208202_0	1283299.AUKG01000001_gene2174	3.721e-175	584.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRHY@84995|Rubrobacteria	84995|Rubrobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158463_k127_208202_3	67281.JNZZ01000011_gene982	2.888e-37	142.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,419JT@629295|Streptomyces griseus group	201174|Actinobacteria	L	FES	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158463_k127_2084304_11	1336208.JADY01000002_gene566	2.623e-91	317.0	COG0627@1|root,COG0627@2|Bacteria,1MX6W@1224|Proteobacteria,2TSCC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	Tannase
SRR25158463_k127_2084304_5	1283287.KB822578_gene2341	2.922e-132	445.0	COG2079@1|root,COG2079@2|Bacteria,2I8CW@201174|Actinobacteria	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158463_k127_2084304_15	1283287.KB822578_gene2340	3.973e-78	274.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2084304_18	1123023.JIAI01000023_gene4263	2.786e-56	213.0	arCOG12117@1|root,2Z9N1@2|Bacteria,2GTM3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
SRR25158463_k127_2084304_13	1283287.KB822578_gene2328	1.134e-87	306.0	COG2079@1|root,COG2079@2|Bacteria,2I8CW@201174|Actinobacteria	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158463_k127_2084304_17	426117.M446_1932	4.445e-69	252.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,1JWG7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158463_k127_2084304_1	1114959.SZMC14600_16656	3.149e-202	644.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4E0R9@85010|Pseudonocardiales	201174|Actinobacteria	S	protein involved in propionate catabolism	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158463_k127_2084304_8	471857.Svir_18600	3.348e-111	385.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria,4E29K@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158463_k127_2084304_16	1123023.JIAI01000001_gene6897	2.344e-76	268.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4E2IV@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158463_k127_2084304_2	1394178.AWOO02000020_gene7444	4.122e-193	621.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4EH4U@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158463_k127_2084304_14	1206731.BAGB01000173_gene123	2.631e-87	295.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4G8WM@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158463_k127_2084304_6	1068978.AMETH_1305	1.018e-131	432.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria,4E5SY@85010|Pseudonocardiales	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158463_k127_2084304_9	1160137.KB907308_gene7053	3.137e-106	356.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_2084304_7	928724.SacglDRAFT_01556	4.442e-128	433.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria,4E5B6@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_2084304_12	1283287.KB822578_gene2332	8.454e-88	305.0	COG0411@1|root,COG0411@2|Bacteria,2IFZQ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158463_k127_2084304_10	1114959.SZMC14600_16616	5.036e-96	320.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DZ0W@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid transport	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158463_k127_2084304_4	1160137.KB907308_gene7049	2.658e-155	501.0	COG2079@1|root,COG2079@2|Bacteria,2I8CW@201174|Actinobacteria,4G1IU@85025|Nocardiaceae	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158463_k127_2084304_20	2074.JNYD01000006_gene1686	1.149e-45	187.0	COG4126@1|root,COG4126@2|Bacteria,2INMJ@201174|Actinobacteria,4EA9N@85010|Pseudonocardiales	201174|Actinobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2084304_3	1283287.KB822578_gene2336	2.95e-185	602.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
SRR25158463_k127_2084304_0	1449068.JMLQ01000002_gene3125	1.361e-219	691.0	COG0044@1|root,COG0044@2|Bacteria,2GKEC@201174|Actinobacteria,4FWD5@85025|Nocardiaceae	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.3,3.5.2.5	ko:K01464,ko:K01465,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00051,M00546	R01993,R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158463_k127_2093477_2	196162.Noca_3984	1.137e-92	318.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4DN3C@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	cebR	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_2093477_0	710696.Intca_0989	7.873e-143	463.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4FEC2@85021|Intrasporangiaceae	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158463_k127_2093477_1	390989.JOEG01000011_gene209	1.55e-133	449.0	COG0441@1|root,COG0441@2|Bacteria,2GNDW@201174|Actinobacteria,4D8EP@85008|Micromonosporales	201174|Actinobacteria	J	Threonine--tRNA ligase	thrS2	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158463_k127_2093477_3	1172188.KB911825_gene3707	4e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,2I8J8@201174|Actinobacteria,4FGFD@85021|Intrasporangiaceae	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_2138651_0	1172188.KB911825_gene3576	1.839e-241	754.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4FE91@85021|Intrasporangiaceae	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158463_k127_2138651_1	1172188.KB911825_gene3577	6.316e-205	641.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4FFXC@85021|Intrasporangiaceae	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158463_k127_2138651_5	1386089.N865_03140	3.401e-128	420.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4FEPF@85021|Intrasporangiaceae	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158463_k127_2138651_4	1380370.JIBA01000016_gene704	4.249e-143	459.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4FFX1@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158463_k127_2138651_7	1386089.N865_03150	2.34e-87	293.0	COG1595@1|root,COG1595@2|Bacteria,2IRIQ@201174|Actinobacteria,4FGXT@85021|Intrasporangiaceae	201174|Actinobacteria	K	SatD family (SatD)	-	-	-	-	-	-	-	-	-	-	-	-	SatD
SRR25158463_k127_2138651_6	1172188.KB911825_gene3586	7.419e-101	336.0	2DN35@1|root,32V90@2|Bacteria,2GSBX@201174|Actinobacteria,4FGJ0@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2138651_2	1172188.KB911825_gene3587	1.236e-198	620.0	COG0039@1|root,COG0039@2|Bacteria,2GJHS@201174|Actinobacteria,4FEX3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158463_k127_2138651_3	1172188.KB911825_gene3588	3.17e-172	545.0	COG1216@1|root,COG1216@2|Bacteria,2IJWC@201174|Actinobacteria,4FHXR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative rhamnosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2,Rhamno_transf
SRR25158463_k127_2138651_9	710696.Intca_1112	1.704e-35	137.0	2BG67@1|root,32A30@2|Bacteria,2IR65@201174|Actinobacteria,4FHMM@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3017
SRR25158463_k127_2138651_8	1380370.JIBA01000016_gene714	2.732e-41	153.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4FFH9@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158463_k127_2154413_8	1068978.AMETH_4420	7.477e-39	147.0	COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4EB5B@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2154413_0	1172188.KB911825_gene3801	0.0	1066.0	COG1112@1|root,COG1198@1|root,COG2852@1|root,COG1112@2|Bacteria,COG1198@2|Bacteria,COG2852@2|Bacteria,2GKJW@201174|Actinobacteria,4FE4S@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF4011
SRR25158463_k127_2154413_2	290399.Arth_0195	1.604e-202	637.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,1W8CV@1268|Micrococcaceae	201174|Actinobacteria	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158463_k127_2154413_3	1121017.AUFG01000039_gene914	1.079e-167	532.0	COG1018@1|root,COG1018@2|Bacteria,2GJSW@201174|Actinobacteria,4FEMH@85021|Intrasporangiaceae	201174|Actinobacteria	C	Stearoyl-CoA 9-desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
SRR25158463_k127_2154413_4	1449044.JMLE01000006_gene1103	1.105e-141	460.0	COG2508@1|root,COG2508@2|Bacteria,2GR38@201174|Actinobacteria,1W87S@1268|Micrococcaceae	201174|Actinobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158463_k127_2154413_1	1380370.JIBA01000013_gene1266	3.974e-217	679.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria,4FFZC@85021|Intrasporangiaceae	201174|Actinobacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
SRR25158463_k127_2154413_7	1463820.JOGW01000003_gene6983	2.618e-71	250.0	COG0590@1|root,COG0590@2|Bacteria,2II3Z@201174|Actinobacteria	201174|Actinobacteria	FJ	deaminase zinc-binding	-	-	-	-	-	-	-	-	-	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158463_k127_2154413_6	526225.Gobs_1402	1.56e-102	344.0	COG1708@1|root,COG1708@2|Bacteria,2GJWQ@201174|Actinobacteria,4EX14@85013|Frankiales	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,NTP_transf_2
SRR25158463_k127_2154413_5	590998.Celf_3367	5.293e-124	407.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158463_k127_2154413_10	1206735.BAGG01000019_gene805	2e-07	52.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4FVZ0@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158463_k127_2175651_1	479431.Namu_1723	9.191e-69	240.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4ET9V@85013|Frankiales	201174|Actinobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
SRR25158463_k127_2175651_0	1386089.N865_18780	3.036e-151	493.0	COG1621@1|root,COG1621@2|Bacteria,2H3S0@201174|Actinobacteria,4FEDK@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
SRR25158463_k127_2186446_0	1385518.N798_04570	1.667e-288	917.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4FEK0@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158463_k127_2186446_1	1089455.MOPEL_130_00780	4.483e-78	269.0	COG2227@1|root,COG2227@2|Bacteria,2GMAR@201174|Actinobacteria,4F6VD@85018|Dermatophilaceae	201174|Actinobacteria	H	Methyltransferase domain	smtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158463_k127_2197895_0	1386089.N865_09320	0.0	1360.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4FFX9@85021|Intrasporangiaceae	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158463_k127_2197895_1	1380370.JIBA01000003_gene2791	6.555e-201	640.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4FF6M@85021|Intrasporangiaceae	201174|Actinobacteria	V	beta-lactamase	blaA2	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158463_k127_2197895_2	1220583.GOACH_16_00100	1.121e-28	119.0	COG1309@1|root,COG1309@2|Bacteria,2GYYS@201174|Actinobacteria,4GDSB@85026|Gordoniaceae	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158463_k127_2207535_11	675635.Psed_1390	1.202e-08	59.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_2207535_0	1283287.KB822575_gene5	2.029e-311	960.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,4DNRG@85009|Propionibacteriales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158463_k127_2207535_5	1121952.ATXT01000013_gene2104	6.512e-72	256.0	COG0149@1|root,COG0149@2|Bacteria,2I8CC@201174|Actinobacteria,4FNPB@85023|Microbacteriaceae	201174|Actinobacteria	G	Triosephosphate isomerase	-	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009758,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0044238,GO:0071704,GO:1901575	5.1.3.39,5.3.1.1	ko:K01803,ko:K20905	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158463_k127_2207535_7	1032480.MLP_03250	6.734e-57	201.0	COG0698@1|root,COG0698@2|Bacteria,2IIDQ@201174|Actinobacteria	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	-	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158463_k127_2207535_1	716928.AJQT01000047_gene2159	7.704e-173	567.0	COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,2TTK3@28211|Alphaproteobacteria,4BADB@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Dak2	-	-	2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01059	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1,Dak2
SRR25158463_k127_2207535_2	450380.JPSY01000001_gene901	1.759e-125	419.0	COG2084@1|root,COG2084@2|Bacteria,2IBF9@201174|Actinobacteria	201174|Actinobacteria	I	Phosphogluconate dehydrogenase (decarboxylating) C-term	-	-	-	-	-	-	-	-	-	-	-	-	F420_oxidored,IlvN,NAD_binding_2,PGDH_C
SRR25158463_k127_2207535_3	1121019.AUMN01000005_gene2875	4.76e-87	295.0	COG1082@1|root,COG1082@2|Bacteria,2GVNW@201174|Actinobacteria,1WASG@1268|Micrococcaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158463_k127_2207535_6	1158050.KB895465_gene3524	2.262e-66	246.0	COG2186@1|root,COG2186@2|Bacteria,2GZJA@201174|Actinobacteria,1W7Z4@1268|Micrococcaceae	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158463_k127_2207535_9	1449044.JMLE01000011_gene3489	4.645e-27	115.0	COG5646@1|root,COG5646@2|Bacteria,2IT4Y@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158463_k127_2207535_10	1193181.BN10_80003	4.096e-22	100.0	2EVGU@1|root,33NX7@2|Bacteria,2I855@201174|Actinobacteria,4FK3F@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2207535_4	285535.JOEY01000002_gene4728	4.601e-75	264.0	COG0741@1|root,COG0741@2|Bacteria,2HKTH@201174|Actinobacteria	201174|Actinobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2207535_8	285535.JOEY01000002_gene4727	3.345e-36	139.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria	201174|Actinobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158463_k127_2238339_10	1386089.N865_08215	5.825e-11	62.0	2CNY9@1|root,32TBE@2|Bacteria,2I8BE@201174|Actinobacteria,4FK3R@85021|Intrasporangiaceae	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158463_k127_2238339_6	1380370.JIBA01000013_gene1541	3.263e-98	345.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4FEN6@85021|Intrasporangiaceae	201174|Actinobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158463_k127_2238339_5	1172188.KB911823_gene425	1.581e-145	472.0	COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4FEK8@85021|Intrasporangiaceae	201174|Actinobacteria	G	OxPP cycle protein OpcA	opcA	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158463_k127_2238339_1	710696.Intca_1691	2.164e-284	904.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4FFXT@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158463_k127_2238339_2	1172188.KB911823_gene427	1.274e-270	856.0	COG0166@1|root,COG0166@2|Bacteria,2HX58@201174|Actinobacteria,4FEPU@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glucose-6-phosphate isomerase	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158463_k127_2238339_3	1193181.BN10_1080007	1.102e-170	542.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4FEYQ@85021|Intrasporangiaceae	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158463_k127_2238339_0	1172188.KB911823_gene429	0.0	1116.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4FF5M@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158463_k127_2238339_4	1172188.KB911823_gene430	1.713e-148	482.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,4FEY1@85021|Intrasporangiaceae	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SRR25158463_k127_2238339_9	1035308.AQYY01000001_gene1274	2.421e-32	134.0	2EHM5@1|root,32ZFJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2238339_8	557599.MKAN_15615	1.836e-53	210.0	2A66V@1|root,30UZC@2|Bacteria,2I9C5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158463_k127_2238339_7	1380370.JIBA01000013_gene1533	4.222e-88	297.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4FG1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158463_k127_224346_6	1172188.KB911824_gene3446	1.655e-26	124.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4FFSS@85021|Intrasporangiaceae	201174|Actinobacteria	D	cell division protein FtsI	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158463_k127_224346_7	367299.JOEE01000004_gene1355	8.25e-19	100.0	2E5Y6@1|root,330MX@2|Bacteria,2IT4J@201174|Actinobacteria,4FGEE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_224346_0	1386089.N865_02040	8.626e-144	467.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4FETT@85021|Intrasporangiaceae	201174|Actinobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158463_k127_224346_4	1089455.MOPEL_032_00230	1.455e-68	237.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4F6SQ@85018|Dermatophilaceae	201174|Actinobacteria	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158463_k127_224346_1	367299.JOEE01000004_gene1352	2.617e-140	461.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FFI4@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158463_k127_224346_3	1386089.N865_02025	1.155e-129	427.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4FFZY@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158463_k127_224346_2	1380370.JIBA01000017_gene2867	1.124e-138	478.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4FE68@85021|Intrasporangiaceae	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158463_k127_224346_8	546414.Deide_03660	9.321e-16	82.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158463_k127_224346_5	1385519.N801_01425	1.606e-43	166.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4FGF5@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_224346_9	1385519.N801_01430	1.643e-06	60.0	2BCR7@1|root,326BP@2|Bacteria,2HBS1@201174|Actinobacteria,4FJTY@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2248564_8	593907.Celgi_2457	6.884e-66	233.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4F0U6@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158463_k127_2248564_0	1386089.N865_07915	1.683e-212	667.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4FE9H@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158463_k127_2248564_9	1122138.AQUZ01000017_gene6575	2.501e-47	175.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria,4DR1X@85009|Propionibacteriales	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158463_k127_2248564_5	1032480.MLP_13820	7.516e-117	392.0	COG1984@1|root,COG1984@2|Bacteria,2GITH@201174|Actinobacteria,4DQVB@85009|Propionibacteriales	201174|Actinobacteria	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B,CT_C_D
SRR25158463_k127_2248564_7	1032480.MLP_13810	4.493e-68	248.0	COG2049@1|root,COG2049@2|Bacteria,2I2R8@201174|Actinobacteria	201174|Actinobacteria	E	allophanate hydrolase subunit 1	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	CT_C_D
SRR25158463_k127_2248564_6	1206720.BAFQ01000104_gene2613	3.122e-94	315.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4FU5S@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the UPF0271 (lamB) family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR25158463_k127_2248564_10	1385518.N798_09560	1.662e-26	124.0	2EDGM@1|root,337CU@2|Bacteria,2IQD1@201174|Actinobacteria,4FGPT@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2248564_13	1172188.KB911823_gene502	2.865e-18	89.0	2EGVE@1|root,33AMN@2|Bacteria,2GX0K@201174|Actinobacteria,4FHU3@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2248564_11	1380370.JIBA01000013_gene1475	6.43e-21	99.0	2ECBY@1|root,336AB@2|Bacteria,2GXKR@201174|Actinobacteria,4FHPG@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2248564_4	1172188.KB911823_gene505	1.156e-119	391.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4FFMM@85021|Intrasporangiaceae	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158463_k127_2248564_1	1385518.N798_11010	3.072e-162	522.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4FEBV@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2248564_3	1380370.JIBA01000013_gene1472	1.409e-124	405.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4FFNC@85021|Intrasporangiaceae	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158463_k127_2248564_2	1380370.JIBA01000013_gene1471	1.591e-145	467.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4FER1@85021|Intrasporangiaceae	201174|Actinobacteria	P	Magnesium	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158463_k127_2248564_12	1048339.KB913029_gene4219	6.758e-21	93.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,4ESCE@85013|Frankiales	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158463_k127_2253567_0	1122182.KB903833_gene5401	2.344e-135	451.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158463_k127_2253567_7	1120949.KB903310_gene880	1.247e-71	251.0	COG2197@1|root,COG2197@2|Bacteria,2GYMP@201174|Actinobacteria,4DM2P@85008|Micromonosporales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158463_k127_2253567_5	1240349.ANGC01000002_gene2255	1.557e-78	295.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4FXYS@85025|Nocardiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158463_k127_2253567_8	1123258.AQXZ01000016_gene2293	4.884e-54	217.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158463_k127_2253567_10	1449976.KALB_2077	1.759e-31	131.0	2B0GT@1|root,31SUB@2|Bacteria,2INZG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2253567_9	1385518.N798_00850	6.334e-40	161.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4FFTR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
SRR25158463_k127_2253567_4	1121385.AQXW01000002_gene142	8.366e-82	286.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,1ZX0Q@145357|Dermacoccaceae	201174|Actinobacteria	K	DeoR C terminal sensor domain	-	-	-	ko:K02081,ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158463_k127_2253567_2	1001240.GY21_06130	8.47e-126	419.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4FKMR@85023|Microbacteriaceae	201174|Actinobacteria	E	Zinc-binding dehydrogenase	-	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SRR25158463_k127_2253567_6	1121385.AQXW01000002_gene139	3.669e-78	285.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_2253567_3	1121385.AQXW01000002_gene138	2.742e-107	355.0	COG0191@1|root,COG0191@2|Bacteria,2H640@201174|Actinobacteria	201174|Actinobacteria	G	Aldolase	gatY	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158463_k127_2253567_1	1121385.AQXW01000002_gene137	4.702e-133	438.0	COG1070@1|root,COG1070@2|Bacteria,2IE7F@201174|Actinobacteria	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158463_k127_2253567_11	679197.HMPREF9336_02528	4.927e-15	75.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158463_k127_2256497_0	1172188.KB911821_gene1721	2.883e-232	731.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4FE9C@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158463_k127_2256497_2	1172188.KB911821_gene1724	2.359e-119	403.0	COG1192@1|root,COG1192@2|Bacteria,2GNEQ@201174|Actinobacteria,4FEP8@85021|Intrasporangiaceae	201174|Actinobacteria	D	Plasmid partitioning protein ParA	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158463_k127_2256497_1	1385520.N802_07325	4.58e-121	398.0	COG2887@1|root,COG2887@2|Bacteria,2I94N@201174|Actinobacteria,4FED4@85021|Intrasporangiaceae	201174|Actinobacteria	L	RecB family exonuclease	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158463_k127_2256497_7	479431.Namu_2266	1.161e-18	93.0	COG4298@1|root,COG4298@2|Bacteria	2|Bacteria	S	yiaA/B two helix domain	MA20_06245	-	-	-	-	-	-	-	-	-	-	-	YiaAB
SRR25158463_k127_2256497_4	1172188.KB911821_gene1733	9.79e-69	248.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria,4FGB3@85021|Intrasporangiaceae	201174|Actinobacteria	U	MarC family integral membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158463_k127_2256497_3	710696.Intca_2570	3.193e-107	357.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4FF9Y@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metal-dependent phosphoesterase	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158463_k127_2256497_5	1463861.JNXE01000008_gene9461	5.925e-46	176.0	COG3548@1|root,COG3548@2|Bacteria,2IQG2@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158463_k127_2259335_6	1146883.BLASA_0959	3.286e-66	247.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,TylF
SRR25158463_k127_2259335_0	1380370.JIBA01000015_gene106	3.697e-185	583.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4FE6R@85021|Intrasporangiaceae	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158463_k127_2259335_8	1122609.AUGT01000025_gene228	9.664e-33	134.0	2EASN@1|root,334UM@2|Bacteria,2IPUJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2259335_5	710696.Intca_0087	2.768e-72	268.0	COG2304@1|root,COG2304@2|Bacteria,2IFH7@201174|Actinobacteria,4FFEQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SRR25158463_k127_2259335_1	1172188.KB911821_gene1822	1.706e-178	571.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4FESU@85021|Intrasporangiaceae	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158463_k127_2259335_3	1122138.AQUZ01000018_gene7522	2.738e-145	481.0	COG0388@1|root,COG0388@2|Bacteria,2H03Y@201174|Actinobacteria,4DV19@85009|Propionibacteriales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1,3.5.5.7	ko:K01501,ko:K01502	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05358,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC01336,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158463_k127_2259335_10	1172188.KB911821_gene1823	3.319e-19	89.0	COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,4FHFV@85021|Intrasporangiaceae	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158463_k127_2259335_7	1193181.BN10_130059	4.087e-35	146.0	2EID2@1|root,33C4E@2|Bacteria,2IH8P@201174|Actinobacteria,4FGUT@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4245)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4245
SRR25158463_k127_2259335_2	710696.Intca_2693	3.506e-163	519.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4FFHG@85021|Intrasporangiaceae	201174|Actinobacteria	G	in Escherichia coli this protein forms a dimer and binds manganese	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158463_k127_2259335_4	1172188.KB911821_gene1826	2.816e-106	353.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4FEAP@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_2259335_9	1410634.JHVD01000004_gene907	1.266e-22	98.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4DPNK@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158463_k127_226848_4	1380370.JIBA01000013_gene1533	2.936e-32	126.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4FG1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158463_k127_226848_3	1298863.AUEP01000006_gene3220	4.439e-40	156.0	COG3818@1|root,COG3818@2|Bacteria,2GRQA@201174|Actinobacteria,4DSBK@85009|Propionibacteriales	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	ko:K06977	-	-	-	-	ko00000	-	-	-	Acetyltransf_1
SRR25158463_k127_226848_2	326424.FRAAL4234	2.748e-54	213.0	COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4ETSP@85013|Frankiales	201174|Actinobacteria	S	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158463_k127_226848_1	1380370.JIBA01000013_gene1531	7.885e-85	299.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4FGAN@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158463_k127_226848_0	1172188.KB911823_gene437	9.455e-101	333.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4FEK6@85021|Intrasporangiaceae	201174|Actinobacteria	V	Multidrug ABC transporter ATPase	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_2279488_0	103733.JNYO01000029_gene843	0.0	1326.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DZS9@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
SRR25158463_k127_2279488_1	1172188.KB911821_gene1215	6.066e-248	773.0	COG2939@1|root,COG2939@2|Bacteria,2GK9N@201174|Actinobacteria,4FEMS@85021|Intrasporangiaceae	201174|Actinobacteria	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SRR25158463_k127_2279488_3	1386089.N865_06140	6.517e-142	470.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4FEHV@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158463_k127_2279488_8	1122182.KB903813_gene2542	7.115e-46	191.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria,4DA3J@85008|Micromonosporales	201174|Actinobacteria	J	2',5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158463_k127_2279488_7	710696.Intca_1199	5.686e-82	294.0	COG1295@1|root,COG1295@2|Bacteria,2GN79@201174|Actinobacteria,4FFHT@85021|Intrasporangiaceae	201174|Actinobacteria	S	Virulence factor BrkB	yhjD	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158463_k127_2279488_5	196162.Noca_0196	1.251e-102	348.0	COG1609@1|root,COG1609@2|Bacteria,2IB6R@201174|Actinobacteria,4DR7Y@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	lacI	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158463_k127_2279488_6	1380370.JIBA01000016_gene654	1.414e-97	335.0	COG1686@1|root,COG1686@2|Bacteria,2GK3M@201174|Actinobacteria,4FFP2@85021|Intrasporangiaceae	201174|Actinobacteria	M	Belongs to the peptidase S11 family	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
SRR25158463_k127_2279488_2	1380370.JIBA01000016_gene648	5.663e-147	476.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria,4FEJE@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2279488_4	471853.Bcav_3565	1.024e-139	445.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria	201174|Actinobacteria	C	succinate dehydrogenase	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158463_k127_2295488_10	1121946.AUAX01000009_gene4513	2.387e-51	195.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4D92H@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158463_k127_2295488_0	397278.JOJN01000012_gene2189	4.23e-218	696.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4DQ0T@85009|Propionibacteriales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158463_k127_2295488_4	1386089.N865_05260	5.571e-132	426.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4FFGI@85021|Intrasporangiaceae	201174|Actinobacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158463_k127_2295488_3	1386089.N865_05265	7.117e-145	467.0	COG4638@1|root,COG4638@2|Bacteria,2I2DT@201174|Actinobacteria,4FFCW@85021|Intrasporangiaceae	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	crtV	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158463_k127_2295488_1	1386089.N865_05270	4.706e-201	651.0	COG3349@1|root,COG3349@2|Bacteria,2GITE@201174|Actinobacteria,4FG32@85021|Intrasporangiaceae	201174|Actinobacteria	S	FAD dependent oxidoreductase	crtU	-	-	ko:K09879	ko00906,map00906	-	R07541,R07560,R07857,R07858	RC01901,RC01965	ko00000,ko00001	-	-	-	Amino_oxidase
SRR25158463_k127_2295488_6	1386089.N865_05275	3.798e-95	317.0	COG0500@1|root,COG2226@2|Bacteria,2HFM8@201174|Actinobacteria,4FH8F@85021|Intrasporangiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	crtT	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR25158463_k127_2295488_8	1151122.AQYD01000007_gene759	2.793e-53	190.0	COG0346@1|root,COG0346@2|Bacteria,2IPGW@201174|Actinobacteria,4FPX0@85023|Microbacteriaceae	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158463_k127_2295488_12	1193181.BN10_540045	1.549e-42	160.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_2295488_15	436229.JOEH01000006_gene2692	7.721e-29	134.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria,2NIBF@228398|Streptacidiphilus	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158463_k127_2295488_5	234621.RER_48310	1.004e-105	366.0	COG4425@1|root,COG4425@2|Bacteria,2GKB5@201174|Actinobacteria,4FUWT@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta-hydrolase family N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158463_k127_2295488_13	675635.Psed_4542	1.576e-39	158.0	COG4954@1|root,COG4954@2|Bacteria,2IFBK@201174|Actinobacteria,4E3QH@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2000
SRR25158463_k127_2295488_7	35754.JNYJ01000030_gene7610	1.798e-94	319.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4DBVJ@85008|Micromonosporales	201174|Actinobacteria	K	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_2295488_14	1172180.KB911787_gene3005	5.54e-35	137.0	COG3324@1|root,COG3324@2|Bacteria,2IKX6@201174|Actinobacteria	201174|Actinobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2295488_11	1172188.KB911820_gene2493	6.941e-43	167.0	COG3576@1|root,COG3576@2|Bacteria,2IG3P@201174|Actinobacteria,4FHHG@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_2295488_9	1283287.KB822577_gene3087	4.465e-53	188.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria,4DRSQ@85009|Propionibacteriales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2295488_2	1172188.KB911820_gene2202	4.347e-188	594.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4FFPW@85021|Intrasporangiaceae	201174|Actinobacteria	E	Cysteine desulfurase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158463_k127_2312212_0	196162.Noca_2333	1.625e-177	571.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4DR22@85009|Propionibacteriales	201174|Actinobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158463_k127_2312212_2	479431.Namu_2396	2.256e-148	481.0	COG0596@1|root,COG2197@1|root,COG0596@2|Bacteria,COG2197@2|Bacteria,2GN4Z@201174|Actinobacteria,4EW1H@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
SRR25158463_k127_2312212_3	479431.Namu_2397	2.704e-109	363.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria,4ESKQ@85013|Frankiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158463_k127_2312212_1	1386089.N865_11175	7.016e-176	566.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4FEAE@85021|Intrasporangiaceae	201174|Actinobacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158463_k127_2315562_5	1386089.N865_05810	5.645e-22	97.0	COG0421@1|root,COG0421@2|Bacteria,2GN8I@201174|Actinobacteria,4FGBP@85021|Intrasporangiaceae	201174|Actinobacteria	E	spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Spermine_synth
SRR25158463_k127_2315562_2	1380370.JIBA01000012_gene3844	1.637e-76	267.0	COG0454@1|root,COG0456@2|Bacteria,2IEMU@201174|Actinobacteria,4FI6X@85021|Intrasporangiaceae	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_2315562_1	397278.JOJN01000005_gene898	6.444e-108	356.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria,4DRBD@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2315562_4	595593.JREV01000048_gene1024	4.633e-34	137.0	COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,1W9SC@1268|Micrococcaceae	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158463_k127_2315562_3	1157637.KB892109_gene4395	2.785e-50	185.0	COG0645@1|root,COG0645@2|Bacteria,2IM2M@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158463_k127_2315562_6	1172188.KB911820_gene3079	4.817e-07	59.0	2B2HR@1|root,31V2S@2|Bacteria,2GUVZ@201174|Actinobacteria,4FHN9@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2315562_0	1380370.JIBA01000012_gene3851	1.044e-155	494.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4FEQP@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158463_k127_2317689_4	1122622.ATWJ01000010_gene1228	3.108e-128	413.0	COG0274@1|root,COG0274@2|Bacteria,2GUM7@201174|Actinobacteria,4FETF@85021|Intrasporangiaceae	201174|Actinobacteria	F	Lysine 2,3-aminomutase	-	-	5.4.3.3	ko:K01844	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	Lys-AminoMut_A
SRR25158463_k127_2317689_8	1298863.AUEP01000008_gene1145	2.564e-39	152.0	COG3593@1|root,COG3593@2|Bacteria,2GMN5@201174|Actinobacteria,4DUZT@85009|Propionibacteriales	201174|Actinobacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2317689_6	1122138.AQUZ01000023_gene7831	2.151e-88	296.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DQ5B@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	senR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158463_k127_2317689_5	479435.Kfla_0355	8.358e-107	359.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4DNPI@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	senS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158463_k127_2317689_3	479431.Namu_2944	7.597e-148	479.0	COG0666@1|root,COG0666@2|Bacteria,2IHX7@201174|Actinobacteria	201174|Actinobacteria	S	ankyrin repeats	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4
SRR25158463_k127_2317689_7	1089453.GOSPT_045_00400	3.528e-43	165.0	COG3548@1|root,COG3548@2|Bacteria,2IQG2@201174|Actinobacteria,4GACC@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158463_k127_2317689_1	1385519.N801_04860	1.908e-174	569.0	COG1249@1|root,COG1249@2|Bacteria,2GNSR@201174|Actinobacteria,4FFPD@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	mtr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657	1.8.1.15	ko:K17883	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158463_k127_2317689_2	367299.JOEE01000008_gene594	4.151e-164	526.0	COG1063@1|root,COG1063@2|Bacteria,2GK3U@201174|Actinobacteria,4FE7C@85021|Intrasporangiaceae	201174|Actinobacteria	E	Zn-dependent alcohol dehydrogenase	-	-	1.4.1.11	ko:K18012	ko00310,map00310	-	R03349	RC00888	ko00000,ko00001,ko01000	-	-	-	-
SRR25158463_k127_2317689_0	1386089.N865_13230	1.176e-255	794.0	COG1509@1|root,COG1509@2|Bacteria,2GM2P@201174|Actinobacteria,4FF3K@85021|Intrasporangiaceae	201174|Actinobacteria	E	Lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	-
SRR25158463_k127_2318842_4	1283283.ATXA01000003_gene1563	9.168e-58	205.0	2AQUC@1|root,31G2H@2|Bacteria,2IET7@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158463_k127_2318842_2	1283283.ATXA01000003_gene1562	2.489e-73	257.0	2C5VJ@1|root,2Z83G@2|Bacteria,2IBA5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2318842_3	313589.JNB_02360	5.72e-72	251.0	COG0454@1|root,COG0456@2|Bacteria,2GK76@201174|Actinobacteria,4FIDN@85021|Intrasporangiaceae	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_2318842_0	1132441.KI519454_gene734	2.027e-174	557.0	COG0596@1|root,COG0596@2|Bacteria,2IAVM@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158463_k127_2318842_1	1211815.CBYP010000068_gene205	4.374e-129	446.0	COG4977@1|root,COG4977@2|Bacteria,2GM0M@201174|Actinobacteria,4EV1J@85013|Frankiales	201174|Actinobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158463_k127_2318842_5	1384054.N790_01830	3.127e-35	152.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,1RP0R@1236|Gammaproteobacteria,1X55T@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	ampC2	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158463_k127_2318842_6	1449044.JMLE01000029_gene123	2.503e-18	85.0	COG0673@1|root,COG0673@2|Bacteria,2GM7J@201174|Actinobacteria	201174|Actinobacteria	K	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158463_k127_2326147_2	1193181.BN10_470019	1.67e-99	341.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4FGIJ@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158463_k127_2326147_0	313589.JNB_18148	1.371e-221	696.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,4FETB@85021|Intrasporangiaceae	201174|Actinobacteria	F	pyrimidine-nucleoside phosphorylase	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158463_k127_2326147_3	1172188.KB911832_gene3915	3.472e-51	186.0	COG0662@1|root,COG0662@2|Bacteria,2IMHT@201174|Actinobacteria,4FGTT@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,EutQ
SRR25158463_k127_2326147_1	1380370.JIBA01000008_gene3013	3.462e-184	584.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4FEWW@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158463_k127_2335274_2	1122609.AUGT01000003_gene2314	7.169e-16	78.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DN7A@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_2335274_1	1317122.ATO12_10855	1.077e-96	338.0	COG3119@1|root,COG3227@1|root,COG3119@2|Bacteria,COG3227@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,2YGJN@290174|Aquimarina	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Laminin_G_3,Sulfatase
SRR25158463_k127_2335274_0	1463926.JOCA01000026_gene6733	6.319e-134	436.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158463_k127_2335274_3	935866.JAER01000007_gene445	1.58e-14	73.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4DPHP@85009|Propionibacteriales	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158463_k127_2362357_2	100226.SCO3203	7.395e-58	204.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	bar	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158463_k127_2362357_4	1306174.JODP01000012_gene6259	1.162e-34	143.0	COG3759@1|root,COG3759@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
SRR25158463_k127_2362357_1	590998.Celf_2731	1.144e-65	230.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria,4F2CY@85016|Cellulomonadaceae	201174|Actinobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158463_k127_2362357_3	457429.ABJI02000519_gene5325	1.545e-57	205.0	COG4319@1|root,COG4319@2|Bacteria,2II1S@201174|Actinobacteria	201174|Actinobacteria	E	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SRR25158463_k127_2362357_0	67267.JNXT01000045_gene6235	7.168e-192	614.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria	201174|Actinobacteria	J	elongation factor G	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158463_k127_2367723_1	1380370.JIBA01000013_gene1514	9.321e-125	424.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4FFDW@85021|Intrasporangiaceae	201174|Actinobacteria	V	FemAB family	femX	-	2.3.2.10	ko:K05363	ko00550,ko01100,map00550,map01100	-	R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
SRR25158463_k127_2367723_0	1385520.N802_17495	9.323e-283	876.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4FESG@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158463_k127_2367723_2	1120959.ATXF01000012_gene3257	1.946e-46	172.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
SRR25158463_k127_2381873_23	1869.MB27_05725	5.866e-28	119.0	COG0438@1|root,COG0438@2|Bacteria,2I97T@201174|Actinobacteria,4DC0N@85008|Micromonosporales	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2381873_8	710696.Intca_3045	8.316e-107	358.0	COG0438@1|root,COG0438@2|Bacteria,2GNPG@201174|Actinobacteria,4FJ4K@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_2381873_4	710696.Intca_3044	3.061e-149	481.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4FFMJ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_2381873_25	477641.MODMU_3889	6.138e-23	105.0	COG3473@1|root,COG3473@2|Bacteria	2|Bacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158463_k127_2381873_22	477641.MODMU_3889	1.258e-28	117.0	COG3473@1|root,COG3473@2|Bacteria	2|Bacteria	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158463_k127_2381873_2	1283287.KB822582_gene2925	2.448e-217	685.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4DT7G@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158463_k127_2381873_15	1206737.BAGF01000058_gene3678	1.197e-60	216.0	COG3797@1|root,COG3797@2|Bacteria,2HR3V@201174|Actinobacteria,4G0JG@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158463_k127_2381873_0	208439.AJAP_15130	0.0	1073.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,4EF7D@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158463_k127_2381873_21	35754.JNYJ01000024_gene9055	4.141e-31	128.0	2CJDS@1|root,32QT3@2|Bacteria,2IFQ7@201174|Actinobacteria,4DIR8@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2381873_17	1476876.JOJO01000011_gene3240	1.016e-42	163.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2381873_14	1385518.N798_00840	4.124e-67	237.0	COG2203@1|root,COG2203@2|Bacteria,2I62P@201174|Actinobacteria,4FH8T@85021|Intrasporangiaceae	201174|Actinobacteria	K	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_2381873_16	188626.HMPREF0321_2382	1.404e-58	213.0	COG2197@1|root,COG3403@1|root,COG2197@2|Bacteria,COG3403@2|Bacteria,2IBB2@201174|Actinobacteria	201174|Actinobacteria	K	YqcI/YcgG family	-	-	-	ko:K09190	-	-	-	-	ko00000	-	-	-	YqcI_YcgG
SRR25158463_k127_2381873_10	1035308.AQYY01000002_gene674	6.723e-90	301.0	COG3665@1|root,COG3665@2|Bacteria,1V1VR@1239|Firmicutes,25DA7@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
SRR25158463_k127_2381873_9	1380370.JIBA01000013_gene1295	1.926e-99	336.0	COG1215@1|root,COG1215@2|Bacteria,2IAQ1@201174|Actinobacteria	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21
SRR25158463_k127_2381873_20	1304876.AZVC01000011_gene3749	5.89e-37	156.0	COG3448@1|root,COG3448@2|Bacteria,2IJXV@201174|Actinobacteria	201174|Actinobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
SRR25158463_k127_2381873_11	1121017.AUFG01000008_gene1456	1.624e-74	258.0	COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria,4FGHF@85021|Intrasporangiaceae	201174|Actinobacteria	G	phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158463_k127_2381873_19	103733.JNYO01000027_gene2462	4.031e-40	164.0	COG0063@1|root,COG0063@2|Bacteria,2IFVX@201174|Actinobacteria,4E23H@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
SRR25158463_k127_2381873_6	1445613.JALM01000036_gene2621	3.088e-139	451.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria,4DXCB@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158463_k127_2381873_24	710696.Intca_0446	5.466e-27	117.0	29V1F@1|root,30GEK@2|Bacteria,2HY55@201174|Actinobacteria,4FJT3@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2381873_3	710696.Intca_0447	8.48e-203	639.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4FHRI@85021|Intrasporangiaceae	201174|Actinobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SRR25158463_k127_2381873_18	710696.Intca_0448	1.669e-41	174.0	2DSGR@1|root,33G2A@2|Bacteria,2GR5N@201174|Actinobacteria,4FJAE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2381873_5	1125971.ASJB01000086_gene2578	1.337e-139	449.0	COG0451@1|root,COG0451@2|Bacteria,2GJ23@201174|Actinobacteria,4E1SN@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SRR25158463_k127_2381873_12	1089545.KB913037_gene7511	1.537e-70	243.0	COG1309@1|root,COG1309@2|Bacteria,2GNHX@201174|Actinobacteria,4E5QR@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_2381873_1	367299.JOEE01000011_gene3171	2.175e-309	960.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,4FEH8@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158463_k127_2381873_7	1121017.AUFG01000007_gene1202	9.102e-110	375.0	COG0300@1|root,COG0300@2|Bacteria,2I2DS@201174|Actinobacteria,4FFCZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158463_k127_2381873_13	1122138.AQUZ01000008_gene3695	7.932e-70	238.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4DT6T@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2395679_6	1386089.N865_07840	1.31e-96	319.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,4FEEV@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158463_k127_2395679_5	479431.Namu_2285	1.398e-103	354.0	COG2273@1|root,COG2273@2|Bacteria,2GJQP@201174|Actinobacteria,4ET9N@85013|Frankiales	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 16	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16,He_PIG,Ricin_B_lectin
SRR25158463_k127_2395679_7	1386089.N865_07835	8.451e-35	134.0	COG0236@1|root,COG0236@2|Bacteria,2IQ43@201174|Actinobacteria,4FH9D@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158463_k127_2395679_2	1172188.KB911827_gene4163	2.173e-166	530.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4FFHC@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005488,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0019637,GO:0019693,GO:0019752,GO:0030497,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033818,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035336,GO:0035337,GO:0035383,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901567,GO:1901568,GO:1901576,GO:1901681	2.3.1.180	ko:K00648,ko:K11608	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iNJ661.Rv0533c	ACP_syn_III,ACP_syn_III_C
SRR25158463_k127_2395679_4	1172188.KB911827_gene4164	5.688e-116	383.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4FFAJ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Biotin attachment protein	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005835,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158463_k127_2395679_3	1121017.AUFG01000050_gene3534	1.061e-143	466.0	COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4FFTQ@85021|Intrasporangiaceae	201174|Actinobacteria	QT	COG2508 Regulator of polyketide synthase expression	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158463_k127_2395679_1	479435.Kfla_0515	7.402e-197	627.0	COG1649@1|root,COG1649@2|Bacteria,2GKNP@201174|Actinobacteria,4DPUR@85009|Propionibacteriales	201174|Actinobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
SRR25158463_k127_2395679_0	1386089.N865_07800	7.099e-247	777.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4FEU3@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158463_k127_2395679_8	1332071.L581_0020	2.824e-34	135.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,1S9NT@1236|Gammaproteobacteria,403EY@613|Serratia	1236|Gammaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158463_k127_2395679_9	1502851.FG93_05451	3.296e-14	79.0	COG3832@1|root,COG3832@2|Bacteria,1RI3S@1224|Proteobacteria,2UB60@28211|Alphaproteobacteria,3JXJH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_2396976_3	367299.JOEE01000001_gene1675	9.13e-121	391.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4FEIZ@85021|Intrasporangiaceae	201174|Actinobacteria	C	NAD(P)H quinone oxidoreductase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158463_k127_2396976_5	1172188.KB911820_gene2787	6.103e-65	231.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4FGNC@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR25158463_k127_2396976_2	591158.SSMG_05027	8.841e-134	432.0	COG0596@1|root,COG0596@2|Bacteria,2GJCT@201174|Actinobacteria	201174|Actinobacteria	F	Alpha beta hydrolase	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158463_k127_2396976_4	1172188.KB911820_gene2786	1.068e-95	319.0	COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria,4FIUC@85021|Intrasporangiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158463_k127_2396976_1	710696.Intca_3455	3.02e-265	825.0	COG3573@1|root,COG3573@2|Bacteria,2GIYM@201174|Actinobacteria,4FFER@85021|Intrasporangiaceae	201174|Actinobacteria	S	Proposed role in polysaccahride synthesis	-	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
SRR25158463_k127_2396976_7	367299.JOEE01000001_gene1655	2.183e-25	117.0	COG1408@1|root,COG3371@1|root,COG1408@2|Bacteria,COG3371@2|Bacteria,2HIFX@201174|Actinobacteria,4FF80@85021|Intrasporangiaceae	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF998,Metallophos
SRR25158463_k127_2396976_0	1386089.N865_13665	1.148e-286	894.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,4FEKR@85021|Intrasporangiaceae	201174|Actinobacteria	I	AMP-dependent synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_2396976_6	1386089.N865_13675	2.27e-47	177.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4FGFN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158463_k127_2398861_6	1386089.N865_14765	1.258e-70	264.0	COG1718@1|root,COG1718@2|Bacteria,2GM3J@201174|Actinobacteria,4FEAQ@85021|Intrasporangiaceae	201174|Actinobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
SRR25158463_k127_2398861_0	710696.Intca_2582	6.946e-246	799.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria,2I8WC@201174|Actinobacteria,4FF4X@85021|Intrasporangiaceae	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158463_k127_2398861_5	1172188.KB911821_gene1744	2.344e-84	291.0	COG4249@1|root,COG4249@2|Bacteria,2IB3R@201174|Actinobacteria,4FG8A@85021|Intrasporangiaceae	201174|Actinobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
SRR25158463_k127_2398861_4	1386089.N865_00235	4.932e-112	382.0	COG1573@1|root,COG1573@2|Bacteria,2IE93@201174|Actinobacteria,4FF76@85021|Intrasporangiaceae	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158463_k127_2398861_2	1386089.N865_00230	2.84e-214	687.0	COG0402@1|root,COG0402@2|Bacteria,2IB7M@201174|Actinobacteria,4FICR@85021|Intrasporangiaceae	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158463_k127_2398861_3	1380370.JIBA01000018_gene519	9.109e-164	520.0	COG2066@1|root,COG2066@2|Bacteria,2GKAV@201174|Actinobacteria,4FGI9@85021|Intrasporangiaceae	201174|Actinobacteria	E	Glutaminase	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase,STAS,cNMP_binding
SRR25158463_k127_2398861_1	1121017.AUFG01000003_gene3432	2.299e-228	710.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FED0@85021|Intrasporangiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_2398861_8	1386089.N865_14740	6.021e-60	214.0	2CAW2@1|root,32RS7@2|Bacteria,2IB15@201174|Actinobacteria,4FGBA@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2398861_7	710696.Intca_2576	2.501e-64	221.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4FFTK@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SRR25158463_k127_2415835_4	367299.JOEE01000008_gene371	9.107e-101	340.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FEAH@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158463_k127_2415835_6	1172188.KB911827_gene4373	1.638e-46	182.0	2E0H9@1|root,32W34@2|Bacteria,2IHPW@201174|Actinobacteria,4FGU9@85021|Intrasporangiaceae	201174|Actinobacteria	S	transcriptional regulator	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010565,GO:0016310,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2415835_8	1385518.N798_05440	1.879e-33	132.0	arCOG05416@1|root,33310@2|Bacteria,2IQR4@201174|Actinobacteria,4FHER@85021|Intrasporangiaceae	201174|Actinobacteria	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2415835_1	345341.KUTG_09151	8.897e-139	450.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4E85Q@85010|Pseudonocardiales	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158463_k127_2415835_5	457429.ABJI02000147_gene7022	1.994e-57	211.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_2415835_0	710696.Intca_1960	9.802e-141	469.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4FEN8@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158463_k127_2415835_3	313589.JNB_01660	4.589e-123	420.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4FG3Q@85021|Intrasporangiaceae	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158463_k127_2415835_2	1380356.JNIK01000013_gene4300	4.294e-125	411.0	COG1680@1|root,COG1680@2|Bacteria,2H2SY@201174|Actinobacteria,4EV3Y@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158463_k127_2415835_9	1380370.JIBA01000013_gene1169	8.654e-19	88.0	28JRZ@1|root,2Z9HI@2|Bacteria,2H9EF@201174|Actinobacteria,4FGAA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRR25158463_k127_2423224_7	1032480.MLP_34050	8.147e-132	432.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4DPQT@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158463_k127_2423224_3	1120949.KB903311_gene695	1.437e-186	595.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_2423224_2	1033730.CAHG01000016_gene536	1.5e-215	690.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria,4DTHS@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_2423224_4	1996.JOFO01000011_gene2860	4.959e-178	565.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4EFV3@85012|Streptosporangiales	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158463_k127_2423224_1	1298863.AUEP01000001_gene752	1.714e-285	885.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4DP1B@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158463_k127_2423224_12	1386089.N865_04620	1.931e-74	261.0	29VND@1|root,30H5P@2|Bacteria,2ICBQ@201174|Actinobacteria,4FHGV@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2423224_14	1283283.ATXA01000005_gene2099	4.775e-32	141.0	2B189@1|root,31TNP@2|Bacteria,2GSQX@201174|Actinobacteria	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158463_k127_2423224_5	1386089.N865_14100	1.461e-171	543.0	COG0252@1|root,COG0252@2|Bacteria,2HUB2@201174|Actinobacteria,4FI4C@85021|Intrasporangiaceae	201174|Actinobacteria	EJ	Asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158463_k127_2423224_11	1386089.N865_14110	8.152e-76	264.0	COG4803@1|root,COG4803@2|Bacteria,2IQV0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158463_k127_2423224_8	1172188.KB911825_gene3780	1.887e-111	372.0	COG3409@1|root,COG3409@2|Bacteria,2HXZI@201174|Actinobacteria,4FIV0@85021|Intrasporangiaceae	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158463_k127_2423224_10	1172188.KB911831_gene3976	6.493e-77	264.0	COG1131@1|root,COG1131@2|Bacteria,2IJGC@201174|Actinobacteria,4FFA8@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	ccmA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_2423224_9	1386089.N865_19560	1.994e-81	289.0	2BX07@1|root,32YGF@2|Bacteria,2IDM2@201174|Actinobacteria,4FGT7@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2423224_0	313589.JNB_18888	8.419e-310	958.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4FE6X@85021|Intrasporangiaceae	201174|Actinobacteria	G	beta-N-acetylhexosaminidase	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRR25158463_k127_2423224_15	710696.Intca_2218	9.754e-13	74.0	2E5FQ@1|root,3307E@2|Bacteria,2INDB@201174|Actinobacteria,4FJME@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2423224_13	1385519.N801_05855	7.823e-41	163.0	COG5640@1|root,COG5640@2|Bacteria,2IB3X@201174|Actinobacteria,4FH3T@85021|Intrasporangiaceae	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158463_k127_2423224_6	1385520.N802_07835	4.55e-168	537.0	COG0493@1|root,COG0493@2|Bacteria,2I57P@201174|Actinobacteria,4FG4K@85021|Intrasporangiaceae	201174|Actinobacteria	E	'glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158463_k127_242465_8	40571.JOEA01000025_gene6016	1.408e-08	61.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria,4E4JM@85010|Pseudonocardiales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	ko:K08365	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158463_k127_242465_5	313589.JNB_10164	2.062e-74	255.0	299JI@1|root,2ZWN1@2|Bacteria,2GMZP@201174|Actinobacteria,4FGEG@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF5063)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5063
SRR25158463_k127_242465_2	1172188.KB911831_gene3990	1.241e-104	342.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4FFJ4@85021|Intrasporangiaceae	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158463_k127_242465_1	1380370.JIBA01000006_gene3390	4.869e-175	555.0	COG2042@1|root,COG3376@2|Bacteria,2GJZB@201174|Actinobacteria,4FG3X@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
SRR25158463_k127_242465_4	1380370.JIBA01000006_gene3389	8.651e-94	312.0	COG0204@1|root,COG0204@2|Bacteria,2GQVG@201174|Actinobacteria,4FFRT@85021|Intrasporangiaceae	201174|Actinobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158463_k127_242465_6	1429046.RR21198_3356	1.383e-66	234.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria,4FTWJ@85025|Nocardiaceae	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158463_k127_242465_0	1440774.Y900_010840	2.245e-235	737.0	COG1953@1|root,COG1953@2|Bacteria,2GJXN@201174|Actinobacteria,234W8@1762|Mycobacteriaceae	201174|Actinobacteria	FH	cytosine purines, uracil, thiamine, allantoin	pucI	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR25158463_k127_242465_3	1429046.RR21198_3354	4.817e-101	334.0	COG4126@1|root,COG4126@2|Bacteria,2GKN4@201174|Actinobacteria,4FU7N@85025|Nocardiaceae	201174|Actinobacteria	E	Hydantoin racemase	hyuE	-	5.1.99.3	ko:K16841	ko00230,ko01120,map00230,map01120	-	R03925	RC01027	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
SRR25158463_k127_242465_7	1385519.N801_08725	3.409e-26	115.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4FEJB@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158463_k127_2449236_4	653045.Strvi_4851	9.493e-109	358.0	COG1028@1|root,COG1028@2|Bacteria,2GP5U@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_2449236_2	1122939.ATUD01000016_gene1863	2.458e-190	623.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CRSI@84995|Rubrobacteria	84995|Rubrobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158463_k127_2449236_5	1121363.KB902184_gene916	1.208e-84	301.0	COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria,22R7T@1653|Corynebacteriaceae	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC4	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158463_k127_2449236_3	749414.SBI_00603	9.287e-140	450.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	oppB4	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158463_k127_2449236_0	1380370.JIBA01000017_gene2903	3.596e-234	734.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4FG34@85021|Intrasporangiaceae	201174|Actinobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158463_k127_2449236_1	1172188.KB911824_gene3411	1.147e-194	620.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4FFRC@85021|Intrasporangiaceae	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158463_k127_2453469_7	591158.SSMG_07441	5.627e-05	51.0	COG0500@1|root,COG2226@2|Bacteria,2GNJS@201174|Actinobacteria	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158463_k127_2453469_0	1193181.BN10_130013	3.009e-229	721.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4FEQ1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158463_k127_2453469_5	105422.BBPM01000005_gene6056	3.145e-63	241.0	2F13R@1|root,33U56@2|Bacteria,2IP51@201174|Actinobacteria,2NKVN@228398|Streptacidiphilus	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158463_k127_2453469_3	1121017.AUFG01000053_gene3593	1.942e-123	408.0	COG0477@1|root,COG2814@2|Bacteria,2GMWE@201174|Actinobacteria,4FFBI@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	ynfM	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
SRR25158463_k127_2453469_4	710696.Intca_2604	3.361e-78	271.0	COG0739@1|root,COG0739@2|Bacteria,2GKXN@201174|Actinobacteria,4FGEK@85021|Intrasporangiaceae	201174|Actinobacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2453469_2	710696.Intca_2603	2.226e-137	451.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4FENI@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
SRR25158463_k127_2453469_1	1172188.KB911821_gene1773	3.809e-175	560.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4FEKF@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158463_k127_2453469_6	1386089.N865_11755	1.336e-09	68.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4FEFV@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158463_k127_24584_10	1123251.ATWM01000005_gene1575	1.825e-37	142.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4FEIX@85021|Intrasporangiaceae	201174|Actinobacteria	C	Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158463_k127_24584_12	1380370.JIBA01000008_gene3024	3.024e-19	93.0	2EJAX@1|root,33D21@2|Bacteria,2HUZB@201174|Actinobacteria,4FHPW@85021|Intrasporangiaceae	201174|Actinobacteria	S	MT0933-like antitoxin protein	-	-	-	-	-	-	-	-	-	-	-	-	MT0933_antitox
SRR25158463_k127_24584_0	1380370.JIBA01000008_gene3025	7.578e-312	967.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4FFCM@85021|Intrasporangiaceae	201174|Actinobacteria	I	carboxylase	bccA	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158463_k127_24584_1	287986.DV20_35730	4.552e-276	876.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DYDJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Carbon monoxide	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158463_k127_24584_5	37919.EP51_03625	1.545e-120	405.0	COG1319@1|root,COG1319@2|Bacteria,2GJF8@201174|Actinobacteria,4FY68@85025|Nocardiaceae	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	xdhB	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158463_k127_24584_8	1121385.AQXW01000004_gene2775	3.454e-69	239.0	COG2080@1|root,COG2080@2|Bacteria,2GMYH@201174|Actinobacteria	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	-	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2
SRR25158463_k127_24584_11	1089545.KB913037_gene2550	5.116e-36	153.0	COG1309@1|root,COG1309@2|Bacteria,2HMBQ@201174|Actinobacteria,4E3XD@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_24584_7	1121017.AUFG01000006_gene1188	2.139e-101	337.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4FEXY@85021|Intrasporangiaceae	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158463_k127_24584_4	1172188.KB911832_gene3933	9.669e-139	446.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria,4FE93@85021|Intrasporangiaceae	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158463_k127_24584_6	590998.Celf_0138	2.413e-116	387.0	COG2124@1|root,COG2124@2|Bacteria,2HCJ1@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158463_k127_24584_9	1386089.N865_18115	5.002e-52	185.0	COG2166@1|root,COG2166@2|Bacteria,2IMBF@201174|Actinobacteria,4FGIP@85021|Intrasporangiaceae	201174|Actinobacteria	S	Fe-S metabolism associated domain	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
SRR25158463_k127_24584_3	710696.Intca_1232	1.191e-167	529.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4FF7F@85021|Intrasporangiaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158463_k127_24584_2	1172188.KB911832_gene3934	6.187e-175	572.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4FFBB@85021|Intrasporangiaceae	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158463_k127_2461637_4	1380393.JHVP01000005_gene3621	5.677e-100	353.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,4EUTU@85013|Frankiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158463_k127_2461637_2	2074.JNYD01000054_gene2351	1.292e-184	611.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4E8X8@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156
SRR25158463_k127_2461637_0	1193181.BN10_610028	1.705e-256	797.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4FET0@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158463_k127_2461637_7	1298860.AUEM01000005_gene2736	9.622e-07	53.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158463_k127_2461637_5	1254432.SCE1572_05170	4.408e-80	284.0	COG2334@1|root,COG2334@2|Bacteria,1R27Y@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158463_k127_2461637_6	1172188.KB911822_gene778	1.098e-56	210.0	COG0572@1|root,COG0572@2|Bacteria,2IR4Y@201174|Actinobacteria,4FI8I@85021|Intrasporangiaceae	201174|Actinobacteria	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_4
SRR25158463_k127_2461637_3	1380370.JIBA01000014_gene1953	9.338e-162	538.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4FFKX@85021|Intrasporangiaceae	201174|Actinobacteria	C	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone	fgd	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0019725,GO:0030312,GO:0031406,GO:0036094,GO:0042592,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046983,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0055114,GO:0065007,GO:0065008,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158463_k127_2461637_1	1121385.AQXW01000004_gene2848	1.419e-185	615.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,1ZX70@145357|Dermacoccaceae	201174|Actinobacteria	H	Aminotransferase class-III	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158463_k127_2480955_10	1032480.MLP_00400	2.013e-27	112.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria,4DSEC@85009|Propionibacteriales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_2480955_5	1032480.MLP_00390	9.464e-140	459.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DNN3@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_2480955_3	1157943.KB892705_gene470	1.049e-140	461.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,232GX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Low temperature requirement	ltrA	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158463_k127_2480955_4	1380370.JIBA01000012_gene3580	1.687e-140	451.0	COG3591@1|root,COG3591@2|Bacteria,2GJVS@201174|Actinobacteria,4FIBD@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2480955_0	1385518.N798_09220	3.58e-249	775.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4FE7T@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158463_k127_2480955_1	1298863.AUEP01000020_gene3583	5.036e-239	775.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4DUP3@85009|Propionibacteriales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,GerE,Guanylate_cyc,Trans_reg_C
SRR25158463_k127_2480955_11	253839.SSNG_04275	6.303e-16	87.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158463_k127_2480955_7	1298863.AUEP01000020_gene3585	6.76e-104	359.0	COG2227@1|root,COG2227@2|Bacteria,2I3C3@201174|Actinobacteria,4DQA0@85009|Propionibacteriales	201174|Actinobacteria	H	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158463_k127_2480955_2	1380370.JIBA01000011_gene3075	9.449e-195	611.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4FEWN@85021|Intrasporangiaceae	201174|Actinobacteria	C	reductase	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158463_k127_2480955_6	405948.SACE_2148	3.985e-109	361.0	COG3618@1|root,COG3618@2|Bacteria,2GM2D@201174|Actinobacteria,4E0W2@85010|Pseudonocardiales	201174|Actinobacteria	C	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158463_k127_2480955_8	2074.JNYD01000011_gene144	1.738e-59	211.0	COG1793@1|root,COG1793@2|Bacteria,2IKMH@201174|Actinobacteria,4EBRN@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	-	-	-	-	-	-	-	-	-	-	-	-	LigD_N
SRR25158463_k127_2480955_9	653045.Strvi_4851	4.963e-47	170.0	COG1028@1|root,COG1028@2|Bacteria,2GP5U@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_2489344_6	930171.Asphe3_17720	6.558e-19	88.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_primase_S
SRR25158463_k127_2489344_5	1380347.JNII01000005_gene3456	8.517e-37	147.0	COG0666@1|root,COG0666@2|Bacteria,2IIAC@201174|Actinobacteria	201174|Actinobacteria	T	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
SRR25158463_k127_2489344_0	1184609.KILIM_011_00450	6.398e-170	539.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4F7MF@85018|Dermatophilaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158463_k127_2489344_1	1380370.JIBA01000013_gene1237	6.186e-140	456.0	COG1073@1|root,COG1073@2|Bacteria,2GMK3@201174|Actinobacteria,4FES9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158463_k127_2489344_3	1386089.N865_12815	7.06e-73	254.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4FG8N@85021|Intrasporangiaceae	201174|Actinobacteria	H	Riboflavin biosynthesis	ribD	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158463_k127_2489344_2	1385521.N803_07445	8.369e-120	393.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4FFBT@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158463_k127_2489344_4	644283.Micau_1897	1.21e-52	202.0	COG2318@1|root,COG2318@2|Bacteria,2II7R@201174|Actinobacteria,4DF76@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158463_k127_2489344_7	1385521.N803_07450	5.472e-16	81.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4FEUI@85021|Intrasporangiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158463_k127_2503861_1	1380370.JIBA01000019_gene992	7.342e-152	487.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4FE77@85021|Intrasporangiaceae	201174|Actinobacteria	C	NADH dehydrogenase	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158463_k127_2503861_2	710696.Intca_0719	1.763e-128	442.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4FFP4@85021|Intrasporangiaceae	201174|Actinobacteria	C	oxidoreductase subunit	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158463_k127_2503861_0	1380370.JIBA01000019_gene989	2.396e-157	499.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4FEGW@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158463_k127_2503861_3	1380370.JIBA01000010_gene2561	5.392e-126	413.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria,4FEIU@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_2503861_4	1380370.JIBA01000010_gene2562	4.642e-11	66.0	COG1879@1|root,COG1879@2|Bacteria,2HEHI@201174|Actinobacteria,4FFTV@85021|Intrasporangiaceae	201174|Actinobacteria	G	Periplasmic binding protein domain	frcB	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
SRR25158463_k127_2539117_3	1386089.N865_07475	1.218e-230	727.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4FF2Y@85021|Intrasporangiaceae	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SRR25158463_k127_2539117_1	1386089.N865_07480	8.024e-263	817.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4FF3Q@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the glutamine synthetase family	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158463_k127_2539117_8	1122138.AQUZ01000002_gene2178	1.163e-45	170.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2539117_9	1120960.ATXG01000005_gene2376	7.172e-45	171.0	2CHCP@1|root,32S5R@2|Bacteria,2IRB0@201174|Actinobacteria,4FQEA@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158463_k127_2539117_4	1172188.KB911820_gene2777	1.996e-197	644.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4FFTJ@85021|Intrasporangiaceae	201174|Actinobacteria	Q	FAD binding domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,DAO,NAD_binding_8
SRR25158463_k127_2539117_0	1172188.KB911827_gene4292	3.189e-299	937.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4FFJG@85021|Intrasporangiaceae	201174|Actinobacteria	S	protease	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
SRR25158463_k127_2539117_6	1172188.KB911827_gene4292	9.047e-58	207.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4FFJG@85021|Intrasporangiaceae	201174|Actinobacteria	S	protease	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
SRR25158463_k127_2539117_2	266940.Krad_3297	9.083e-242	760.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158463_k127_2539117_7	479433.Caci_4452	2.298e-47	175.0	COG1670@1|root,COG1670@2|Bacteria,2IE9P@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158463_k127_2539117_5	68199.JNZO01000002_gene1505	2.182e-108	359.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	tpdA	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_2556988_1	1121017.AUFG01000013_gene1967	1.073e-74	253.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4FF9N@85021|Intrasporangiaceae	201174|Actinobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	cobQ2	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158463_k127_2556988_2	644283.Micau_6261	2.42e-48	181.0	2E6RN@1|root,331BS@2|Bacteria,2GME4@201174|Actinobacteria,4DE0N@85008|Micromonosporales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158463_k127_2556988_4	1068980.ARVW01000001_gene3366	2.293e-12	80.0	COG3595@1|root,COG3595@2|Bacteria,2I8IR@201174|Actinobacteria,4E5VQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158463_k127_2556988_0	1125971.ASJB01000028_gene7840	6.922e-141	464.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DYYS@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158463_k127_2556988_3	1385521.N803_06200	7.366e-39	150.0	COG2518@1|root,COG2518@2|Bacteria,2HXGI@201174|Actinobacteria,4FGK8@85021|Intrasporangiaceae	201174|Actinobacteria	O	Protein-L-isoaspartate carboxylmethyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158463_k127_2558420_8	1172188.KB911830_gene3871	2.102e-70	248.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4FED8@85021|Intrasporangiaceae	201174|Actinobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158463_k127_2558420_4	909613.UO65_6473	3.802e-129	420.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4DXT8@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158463_k127_2558420_1	710696.Intca_0828	6.191e-213	700.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4FG7G@85021|Intrasporangiaceae	201174|Actinobacteria	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
SRR25158463_k127_2558420_5	1068978.AMETH_3853	7.074e-115	389.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4E18A@85010|Pseudonocardiales	201174|Actinobacteria	C	overlaps another CDS with the same product name	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158463_k127_2558420_0	710696.Intca_0826	2.596e-245	772.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4FGA8@85021|Intrasporangiaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158463_k127_2558420_3	1463900.JOIX01000010_gene5929	3.919e-137	453.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158463_k127_2558420_6	67315.JOBD01000015_gene6578	7.653e-79	272.0	COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158463_k127_2558420_10	1463861.JNXE01000002_gene6467	4.427e-32	130.0	COG1846@1|root,COG1846@2|Bacteria,2II35@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158463_k127_2558420_7	1033730.CAHG01000014_gene1857	7.265e-71	246.0	arCOG05626@1|root,2Z9D9@2|Bacteria,2IIAB@201174|Actinobacteria,4DSNX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2558420_2	479435.Kfla_5969	5.515e-179	580.0	COG3853@1|root,COG3853@2|Bacteria,2GNWN@201174|Actinobacteria,4DPZG@85009|Propionibacteriales	201174|Actinobacteria	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
SRR25158463_k127_2558420_9	479435.Kfla_5970	1.702e-67	235.0	2BDZ4@1|root,327PI@2|Bacteria,2IN10@201174|Actinobacteria,4DUTE@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2558420_11	1386089.N865_09345	1.133e-09	68.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria,4FEFU@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158463_k127_2573769_1	1463917.JODC01000007_gene7107	4.521e-186	592.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_2573769_3	653045.Strvi_3119	7.273e-85	289.0	COG1309@1|root,COG1309@2|Bacteria,2GNBS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158463_k127_2573769_5	1385518.N798_01420	8.649e-52	194.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4FH6B@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158463_k127_2573769_2	1386089.N865_05525	1.065e-142	460.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4FECM@85021|Intrasporangiaceae	201174|Actinobacteria	O	molecular chaperone	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158463_k127_2573769_4	710696.Intca_3298	3.601e-66	234.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4FH8C@85021|Intrasporangiaceae	201174|Actinobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158463_k127_2573769_0	1184609.KILIM_044_00430	1.289e-274	852.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4F639@85018|Dermatophilaceae	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158463_k127_2602004_2	931627.MycrhDRAFT_5250	2.036e-54	193.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,23CRV@1762|Mycobacteriaceae	201174|Actinobacteria	O	Cyclic nucleotide-monophosphate binding domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158463_k127_2602004_0	1386089.N865_10465	8.216e-65	227.0	COG0346@1|root,COG0346@2|Bacteria,2IFKS@201174|Actinobacteria,4FH65@85021|Intrasporangiaceae	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
SRR25158463_k127_2602004_6	1463936.JOJI01000048_gene6155	4.976e-11	74.0	COG0454@1|root,COG1042@1|root,COG0456@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria	201174|Actinobacteria	C	CoA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158463_k127_2602004_1	1386089.N865_10715	8.261e-56	197.0	COG3795@1|root,COG3795@2|Bacteria,2IMMY@201174|Actinobacteria,4FGV2@85021|Intrasporangiaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_2602004_4	1463921.JODF01000002_gene3034	7.564e-44	170.0	COG1191@1|root,COG1191@2|Bacteria,2GKBB@201174|Actinobacteria	201174|Actinobacteria	K	rna polymerase sigma factor	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158463_k127_2602004_5	1206737.BAGF01000152_gene6514	5.284e-28	119.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,4G175@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_2602004_3	313589.JNB_02205	5.13e-45	166.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,4FFDI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158463_k127_2619801_0	1121017.AUFG01000008_gene1428	1.511e-201	641.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4FG1X@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158463_k127_2619801_1	1386089.N865_14290	8.66e-98	327.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4FEE5@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158463_k127_2619801_5	710696.Intca_0457	2.221e-17	87.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4FEE5@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158463_k127_2619801_2	1386089.N865_07780	1.592e-62	221.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4FGWJ@85021|Intrasporangiaceae	201174|Actinobacteria	O	Peroxiredoxin	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
SRR25158463_k127_2619801_3	710696.Intca_2058	1.236e-41	159.0	2B57P@1|root,32TPU@2|Bacteria,2I89I@201174|Actinobacteria,4FK3P@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3052)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158463_k127_2619801_4	1184609.KILIM_016_00500	1.31e-33	132.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4F7G2@85018|Dermatophilaceae	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158463_k127_2626346_9	1283283.ATXA01000011_gene4703	2.363e-144	474.0	COG0531@1|root,COG0531@2|Bacteria,2GK5V@201174|Actinobacteria,4EUSY@85013|Frankiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158463_k127_2626346_21	1121924.ATWH01000002_gene3843	2.187e-47	178.0	COG1917@1|root,COG1917@2|Bacteria,2HT7G@201174|Actinobacteria,4FSA8@85023|Microbacteriaceae	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_2626346_1	1108045.GORHZ_159_00220	9.01e-278	868.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158463_k127_2626346_13	43354.JOIJ01000002_gene4475	7.782e-111	363.0	COG1028@1|root,COG1028@2|Bacteria,2GM3I@201174|Actinobacteria,4E3K3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_2626346_18	36809.MAB_3911	3.44e-70	255.0	COG3319@1|root,COG3319@2|Bacteria,2GJ5V@201174|Actinobacteria,236RS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
SRR25158463_k127_2626346_11	1463887.KL590044_gene8337	1.077e-113	385.0	COG1404@1|root,COG1404@2|Bacteria,2GKJR@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158463_k127_2626346_20	326424.FRAAL3052	3.177e-59	224.0	COG1028@1|root,COG1028@2|Bacteria,2I4ES@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158463_k127_2626346_8	1343740.M271_00560	2.161e-146	471.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2626346_3	1343740.M271_00570	2.163e-206	659.0	COG1574@1|root,COG1574@2|Bacteria,2GV7B@201174|Actinobacteria	201174|Actinobacteria	S	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158463_k127_2626346_12	1120948.KB903217_gene1505	6.01e-112	388.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E0YM@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_2626346_19	709986.Deima_1929	1.915e-60	225.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
SRR25158463_k127_2626346_15	469383.Cwoe_4784	1.636e-89	326.0	COG0477@1|root,COG2814@2|Bacteria,2H8UD@201174|Actinobacteria,4CRSM@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_2626346_5	749414.SBI_09838	9.516e-166	533.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158463_k127_2626346_17	1343740.M271_00500	4.153e-73	258.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158463_k127_2626346_22	1343740.M271_00530	3.279e-45	175.0	2CIU6@1|root,32S8H@2|Bacteria,2GSNM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2626346_2	1343740.M271_00535	7.526e-228	719.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158463_k127_2626346_14	1343740.M271_00540	1.61e-94	320.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158463_k127_2626346_7	1240349.ANGC01000003_gene2137	5.005e-160	512.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria,4FWA9@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_2626346_6	935866.JAER01000004_gene3893	7.483e-162	518.0	COG1960@1|root,COG1960@2|Bacteria,2HNCS@201174|Actinobacteria,4DTMZ@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_2626346_10	1045009.AFXQ01000009_gene801	1.099e-114	374.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158463_k127_2626346_4	1429046.RR21198_4961	5.063e-176	559.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FV60@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158463_k127_2626346_0	1429046.RR21198_4960	1.2e-287	887.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4G0A1@85025|Nocardiaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158463_k127_2626346_16	1045009.AFXQ01000009_gene780	7.048e-83	279.0	COG2030@1|root,COG2030@2|Bacteria,2HG1K@201174|Actinobacteria,1WBI5@1268|Micrococcaceae	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158463_k127_2626346_24	1045009.AFXQ01000009_gene779	1.045e-12	68.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,1WAGW@1268|Micrococcaceae	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158463_k127_2627820_0	67373.JOBF01000007_gene2299	1.42e-178	568.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158463_k127_2627820_6	405948.SACE_3030	1.63e-68	238.0	COG0563@1|root,COG0563@2|Bacteria,2IJ2R@201174|Actinobacteria,4E56K@85010|Pseudonocardiales	201174|Actinobacteria	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
SRR25158463_k127_2627820_2	196162.Noca_2866	7.64e-100	340.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria,4DNXG@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158463_k127_2627820_1	196162.Noca_2867	2.44e-139	489.0	COG3127@1|root,COG3127@2|Bacteria,2I5BW@201174|Actinobacteria,4DQAN@85009|Propionibacteriales	201174|Actinobacteria	Q	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2627820_7	196162.Noca_2865	2.322e-51	204.0	COG1136@1|root,COG1136@2|Bacteria,2IENJ@201174|Actinobacteria,4DQUN@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter	ytrE	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_2627820_9	557599.MKAN_22040	1.708e-43	175.0	2DNJR@1|root,32XUV@2|Bacteria,2IJWF@201174|Actinobacteria,239KZ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2627820_3	471853.Bcav_3309	2.306e-95	329.0	COG1028@1|root,COG1028@2|Bacteria,2GP7P@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_2627820_10	926564.KI911697_gene273	5.479e-27	114.0	COG2350@1|root,COG2350@2|Bacteria,2GV9T@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_2627820_4	1150864.MILUP08_44110	1.159e-78	283.0	COG1708@1|root,COG1708@2|Bacteria,2IE97@201174|Actinobacteria,4DCI5@85008|Micromonosporales	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111,NTP_transf_2
SRR25158463_k127_2627820_8	446466.Cfla_3473	4.014e-45	171.0	COG0454@1|root,COG0456@2|Bacteria,2GPVQ@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_2627820_5	1193181.BN10_50017	3.401e-74	271.0	COG2304@1|root,COG2304@2|Bacteria,2GUB3@201174|Actinobacteria,4FFUP@85021|Intrasporangiaceae	201174|Actinobacteria	P	Von Willebrand factor	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,VWA
SRR25158463_k127_2646057_8	1323361.JPOC01000046_gene772	1.902e-23	104.0	COG0657@1|root,COG0657@2|Bacteria,2IE8R@201174|Actinobacteria,4FYMX@85025|Nocardiaceae	201174|Actinobacteria	I	Steryl acetyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158463_k127_2646057_7	1386089.N865_12215	1.818e-45	174.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4FH47@85021|Intrasporangiaceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158463_k127_2646057_9	1274.HX89_05215	1.108e-10	69.0	2EUTX@1|root,33N9F@2|Bacteria,2I0SQ@201174|Actinobacteria,1ZW9J@145357|Dermacoccaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158463_k127_2646057_5	1033730.CAHG01000015_gene720	4.052e-73	250.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4DQGR@85009|Propionibacteriales	201174|Actinobacteria	O	Redoxin	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158463_k127_2646057_0	1123251.ATWM01000003_gene1140	1.076e-171	555.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4FE2W@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158463_k127_2646057_4	367299.JOEE01000003_gene2865	1.351e-99	332.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4FGS6@85021|Intrasporangiaceae	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158463_k127_2646057_2	367299.JOEE01000003_gene2866	8.601e-136	436.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4FG22@85021|Intrasporangiaceae	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158463_k127_2646057_3	710696.Intca_1325	6.384e-109	360.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4FFHA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metal-dependent hydrolase	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158463_k127_2646057_1	1121017.AUFG01000055_gene20	1.034e-141	454.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4FFI1@85021|Intrasporangiaceae	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158463_k127_2646057_6	1151061.CAJY01000028_gene821	8.248e-52	196.0	COG2334@1|root,COG2334@2|Bacteria,2I4QD@201174|Actinobacteria	201174|Actinobacteria	S	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	-	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
SRR25158463_k127_2646057_10	1210046.B277_11425	2.076e-09	58.0	2E4AX@1|root,32Z6K@2|Bacteria,2HXQ7@201174|Actinobacteria,4FHIK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158463_k127_2654741_5	1380390.JIAT01000014_gene6115	9.47e-34	146.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4CSK4@84995|Rubrobacteria	84995|Rubrobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158463_k127_2654741_2	1380370.JIBA01000012_gene3625	3.968e-147	484.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4FGE3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158463_k127_2654741_4	1206744.BAGL01000050_gene955	2.746e-99	337.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4G3XZ@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2654741_0	1386089.N865_21055	4.553e-246	765.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2GIXE@201174|Actinobacteria,4FEFP@85021|Intrasporangiaceae	201174|Actinobacteria	EK	Cystathionine beta-synthase	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158463_k127_2654741_3	1385519.N801_16355	2.294e-117	411.0	COG2755@1|root,COG2755@2|Bacteria,2GMVS@201174|Actinobacteria,4FF0T@85021|Intrasporangiaceae	201174|Actinobacteria	E	G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158463_k127_2654741_1	1121017.AUFG01000013_gene1908	8.825e-181	571.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4FFIM@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158463_k127_2675100_7	1240349.ANGC01000006_gene1337	9.42e-95	324.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4FZ5G@85025|Nocardiaceae	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158463_k127_2675100_1	1108045.GORHZ_159_00140	1.369e-218	696.0	COG1960@1|root,COG1960@2|Bacteria,2IBZX@201174|Actinobacteria,4GFRF@85026|Gordoniaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_2675100_0	1045009.AFXQ01000009_gene777	1.103e-289	900.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,1WAK2@1268|Micrococcaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_2675100_2	1240349.ANGC01000006_gene1340	7.862e-183	590.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4FXZ1@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2675100_10	1206725.BAFU01000247_gene2519	5.924e-59	214.0	COG1028@1|root,COG1028@2|Bacteria,2HFNW@201174|Actinobacteria,4G76W@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.304,1.1.1.76	ko:K18009	ko00650,map00650	-	R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158463_k127_2675100_11	1429046.RR21198_4232	6.14e-20	96.0	2APPW@1|root,31ETJ@2|Bacteria,2GYQS@201174|Actinobacteria,4G37U@85025|Nocardiaceae	201174|Actinobacteria	S	Ring hydroxylating beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158463_k127_2675100_6	269800.Tfu_1283	9.732e-97	329.0	COG1028@1|root,COG1028@2|Bacteria,2GK78@201174|Actinobacteria,4EMRU@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_2675100_9	1121933.AUHH01000031_gene3033	2.139e-63	222.0	COG3871@1|root,COG3871@2|Bacteria,2INWZ@201174|Actinobacteria	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR25158463_k127_2675100_3	222534.KB893715_gene1684	4.692e-174	554.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4EUGI@85013|Frankiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158463_k127_2675100_4	1108045.GORHZ_159_00090	1.207e-117	388.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4GAN1@85026|Gordoniaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158463_k127_2675100_8	1108045.GORHZ_159_00080	5.881e-92	322.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4GAIJ@85026|Gordoniaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158463_k127_2675100_5	1268303.RHODMAR_1523	4.338e-105	345.0	COG0447@1|root,COG0447@2|Bacteria,2HGHM@201174|Actinobacteria,4FZY1@85025|Nocardiaceae	201174|Actinobacteria	H	Enoyl-CoA hydratase/isomerase	-	-	4.1.3.36	ko:K01661,ko:K07536	ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220	M00116,M00540	R05592,R07263	RC01429,RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158463_k127_2690566_6	367299.JOEE01000003_gene2998	5.187e-55	214.0	COG2385@1|root,COG5479@1|root,COG2385@2|Bacteria,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4FJZJ@85021|Intrasporangiaceae	201174|Actinobacteria	DM	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,FG-GAP
SRR25158463_k127_2690566_9	1206732.BAGD01000086_gene3818	6.505e-26	124.0	COG5479@1|root,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4FWFJ@85025|Nocardiaceae	201174|Actinobacteria	M	protein potentially involved in peptidoglycan biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SRR25158463_k127_2690566_0	710696.Intca_1885	0.0	1088.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4FFPP@85021|Intrasporangiaceae	201174|Actinobacteria	J	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158463_k127_2690566_5	909613.UO65_6340	1.678e-76	265.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DXF3@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158463_k127_2690566_10	345341.KUTG_08804	1.068e-09	70.0	COG4585@1|root,COG4585@2|Bacteria,2GQQ8@201174|Actinobacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Sensor
SRR25158463_k127_2690566_7	1123258.AQXZ01000013_gene1915	3.164e-37	162.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4FU5V@85025|Nocardiaceae	201174|Actinobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158463_k127_2690566_4	710696.Intca_1888	3.162e-85	292.0	COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,4FFHW@85021|Intrasporangiaceae	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158463_k127_2690566_2	367299.JOEE01000008_gene509	3.974e-169	542.0	COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria,4FFTI@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_2690566_1	1172188.KB911823_gene642	8.803e-202	636.0	COG0183@1|root,COG0183@2|Bacteria,2GJI8@201174|Actinobacteria,4FFR2@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158463_k127_2690566_8	1380370.JIBA01000013_gene1343	8.334e-28	116.0	291E7@1|root,2ZP12@2|Bacteria,2I75R@201174|Actinobacteria,4FH3I@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2690566_3	1172188.KB911820_gene3114	5.294e-88	295.0	COG0558@1|root,COG0558@2|Bacteria,2I5BP@201174|Actinobacteria,4FEZT@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf,Sulfatase
SRR25158463_k127_2700485_5	1385518.N798_00490	7.797e-60	211.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4FEKI@85021|Intrasporangiaceae	201174|Actinobacteria	E	asparaginase	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158463_k127_2700485_4	743718.Isova_2680	1.899e-64	230.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4F4IX@85017|Promicromonosporaceae	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158463_k127_2700485_6	1380370.JIBA01000004_gene2315	4.047e-32	128.0	2EHMU@1|root,33BDI@2|Bacteria,2GQGA@201174|Actinobacteria,4FHT4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2516)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2516
SRR25158463_k127_2700485_3	1172188.KB911830_gene3845	1.126e-68	235.0	COG0662@1|root,COG0662@2|Bacteria,2IPIR@201174|Actinobacteria,4FH33@85021|Intrasporangiaceae	201174|Actinobacteria	G	Mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K01809,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer
SRR25158463_k127_2700485_1	367299.JOEE01000006_gene688	2.113e-123	400.0	COG4122@1|root,COG4122@2|Bacteria,2GK2F@201174|Actinobacteria,4FF27@85021|Intrasporangiaceae	201174|Actinobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2700485_0	1172188.KB911830_gene3842	3.378e-189	601.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4FEWH@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_2700485_2	1172188.KB911830_gene3841	1.025e-71	253.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4FGHN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158463_k127_2710482_0	1172188.KB911824_gene3455	9.319e-212	664.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4FE51@85021|Intrasporangiaceae	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158463_k127_2710482_1	1172188.KB911824_gene3456	8.454e-113	370.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4FFF8@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158463_k127_2710482_2	1172188.KB911824_gene3457	5.413e-106	352.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4FG49@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158463_k127_2710482_3	1172188.KB911824_gene3458	3.236e-84	299.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4FFP8@85021|Intrasporangiaceae	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158463_k127_2722947_1	1385521.N803_07395	2.784e-90	307.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4FEAF@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158463_k127_2722947_0	367299.JOEE01000008_gene451	2.072e-111	366.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4FE6U@85021|Intrasporangiaceae	201174|Actinobacteria	S	Chlorite dismutase	cld	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158463_k127_2722947_2	1122622.ATWJ01000009_gene3031	1.973e-74	253.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4FGN2@85021|Intrasporangiaceae	201174|Actinobacteria	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158463_k127_2722947_3	1283283.ATXA01000004_gene4415	7.45e-55	202.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
SRR25158463_k127_2729626_3	710696.Intca_1309	2.09e-51	196.0	2CAFG@1|root,32RRB@2|Bacteria,2IQ98@201174|Actinobacteria,4FHF8@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3039)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3039
SRR25158463_k127_2729626_1	1172188.KB911824_gene3224	1.075e-123	401.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4FFI1@85021|Intrasporangiaceae	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158463_k127_2729626_2	1380370.JIBA01000002_gene2598	1.47e-112	371.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4FGBV@85021|Intrasporangiaceae	201174|Actinobacteria	K	Uncharacterized ACR, COG1678	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158463_k127_2729626_0	1172188.KB911824_gene3222	1.413e-304	946.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4FFEI@85021|Intrasporangiaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	rhlE_2	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158463_k127_2736738_13	40571.JOEA01000007_gene6561	1.205e-40	169.0	COG0566@1|root,COG0566@2|Bacteria,2GNJK@201174|Actinobacteria,4DYV5@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158463_k127_2736738_5	1380370.JIBA01000013_gene1492	4.986e-89	299.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4FGF3@85021|Intrasporangiaceae	201174|Actinobacteria	S	LmbE family	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158463_k127_2736738_6	1122609.AUGT01000024_gene430	1.213e-87	295.0	COG1409@1|root,COG1409@2|Bacteria,2HKQQ@201174|Actinobacteria,4DS0J@85009|Propionibacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
SRR25158463_k127_2736738_1	1386089.N865_18300	7.664e-222	691.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4FEC3@85021|Intrasporangiaceae	201174|Actinobacteria	C	tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_2736738_8	1380356.JNIK01000014_gene3242	7.46e-72	248.0	COG0431@1|root,COG0431@2|Bacteria,2IHWU@201174|Actinobacteria,4ESVD@85013|Frankiales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158463_k127_2736738_3	2074.JNYD01000007_gene1961	1.351e-163	529.0	COG0436@1|root,COG0436@2|Bacteria,2I9CX@201174|Actinobacteria,4E9IE@85010|Pseudonocardiales	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	4.1.1.12	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	-	R00397,R00863	RC00282,RC00399,RC00400	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158463_k127_2736738_10	1370121.AUWS01000024_gene2377	9.827e-61	213.0	COG3542@1|root,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria,238MX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5,DUF952
SRR25158463_k127_2736738_15	1435356.Y013_03350	1.04e-39	158.0	COG0829@1|root,COG0829@2|Bacteria	2|Bacteria	O	nickel cation binding	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
SRR25158463_k127_2736738_4	1184609.KILIM_007_00100	2.314e-106	350.0	COG0378@1|root,COG0378@2|Bacteria,2GNUV@201174|Actinobacteria	201174|Actinobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
SRR25158463_k127_2736738_14	1274.HX89_01650	1.529e-40	169.0	COG0830@1|root,COG0830@2|Bacteria,2GN66@201174|Actinobacteria	201174|Actinobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
SRR25158463_k127_2736738_0	1077974.GOEFS_096_00240	2.505e-296	921.0	COG0804@1|root,COG0804@2|Bacteria,2GM7X@201174|Actinobacteria,4GCAM@85026|Gordoniaceae	201174|Actinobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	GO:0008150,GO:0040007	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	iNJ661.Rv1850	Amidohydro_1,Urease_alpha
SRR25158463_k127_2736738_12	521096.Tpau_3410	6.163e-44	164.0	COG0832@1|root,COG0832@2|Bacteria,2IKR8@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
SRR25158463_k127_2736738_11	408672.NBCG_01752	1.418e-48	175.0	COG0831@1|root,COG0831@2|Bacteria,2IKNA@201174|Actinobacteria,4DR21@85009|Propionibacteriales	201174|Actinobacteria	E	Urease, gamma subunit	ureA	-	3.5.1.5	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
SRR25158463_k127_2736738_9	1463820.JOGW01000027_gene6897	1.215e-61	217.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria	201174|Actinobacteria	S	BioY protein	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158463_k127_2736738_2	675635.Psed_4718	3.476e-164	534.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DX83@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	ligC	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158463_k127_2736738_16	743718.Isova_0429	3.217e-08	65.0	2DTIB@1|root,33KGH@2|Bacteria,2H046@201174|Actinobacteria,4F50G@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2736738_17	446466.Cfla_0529	2.681e-05	51.0	2DTIB@1|root,33KGH@2|Bacteria,2H046@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2736738_7	477641.MODMU_1806	2.503e-78	267.0	COG0262@1|root,COG0262@2|Bacteria,2IF7J@201174|Actinobacteria,4EX76@85013|Frankiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_2759360_15	426117.M446_3518	0.000222	48.0	COG4177@1|root,COG4177@2|Bacteria,1MZDJ@1224|Proteobacteria,2TRYJ@28211|Alphaproteobacteria,1JYZ6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	U	Branched-chain amino acid transport system / permease component	MA20_23495	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_2759360_4	1380370.JIBA01000014_gene2008	2.885e-161	537.0	COG4177@1|root,COG4177@2|Bacteria,2GNZK@201174|Actinobacteria,4FFYI@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_2759360_5	1385519.N801_01475	1.095e-149	477.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4FF5G@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_2759360_0	1172188.KB911821_gene1524	1.106e-215	676.0	COG0683@1|root,COG0683@2|Bacteria,2HX4M@201174|Actinobacteria,4FECA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Branched-chain amino acid ABC transporter substrate-binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158463_k127_2759360_8	1172188.KB911821_gene1525	8.182e-110	365.0	COG0410@1|root,COG0410@2|Bacteria,2I8P0@201174|Actinobacteria,4FFKU@85021|Intrasporangiaceae	201174|Actinobacteria	E	Histidinol dehydrogenase	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158463_k127_2759360_7	1172188.KB911821_gene1526	7.336e-121	392.0	COG0411@1|root,COG0411@2|Bacteria,2I3Z1@201174|Actinobacteria,4FG1H@85021|Intrasporangiaceae	201174|Actinobacteria	E	amino acid ABC transporter, ATP-binding protein	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158463_k127_2759360_9	1172188.KB911826_gene145	1.128e-106	351.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,4FFGD@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	tipA	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1,TipAS
SRR25158463_k127_2759360_11	367299.JOEE01000004_gene1032	1.365e-63	222.0	COG3797@1|root,COG3797@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
SRR25158463_k127_2759360_6	867845.KI911784_gene1260	6.448e-134	464.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
SRR25158463_k127_2759360_13	1120950.KB892772_gene1152	3.949e-21	97.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DSNT@85009|Propionibacteriales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158463_k127_2759360_10	313589.JNB_09559	4.452e-89	298.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4FG27@85021|Intrasporangiaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
SRR25158463_k127_2759360_3	1386089.N865_09180	1.301e-178	568.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4FFBG@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA polymerase III subunit delta	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158463_k127_2759360_2	367299.JOEE01000001_gene1922	7.652e-186	596.0	COG0596@1|root,COG0596@2|Bacteria,2GJYS@201174|Actinobacteria,4FF86@85021|Intrasporangiaceae	201174|Actinobacteria	S	proteinase	slpD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158463_k127_2759360_12	1306174.JODP01000003_gene1813	1.653e-38	159.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158463_k127_2759360_1	931627.MycrhDRAFT_5250	3.076e-213	672.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,23CRV@1762|Mycobacteriaceae	201174|Actinobacteria	O	Cyclic nucleotide-monophosphate binding domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
SRR25158463_k127_2778411_4	1386089.N865_17130	2.534e-118	386.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4FEI5@85021|Intrasporangiaceae	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158463_k127_2778411_12	1121017.AUFG01000001_gene3010	1.118e-16	91.0	COG4291@1|root,COG4291@2|Bacteria,2IIVD@201174|Actinobacteria,4FF5P@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SRR25158463_k127_2778411_9	561175.KB894096_gene755	4.123e-28	115.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158463_k127_2778411_5	1463879.JOHP01000077_gene465	6.878e-71	244.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158463_k127_2778411_3	134676.ACPL_2891	2.361e-127	426.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DD1T@85008|Micromonosporales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158463_k127_2778411_7	479433.Caci_8493	1.261e-45	171.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_2778411_2	1172188.KB911822_gene1143	4.815e-131	424.0	COG2267@1|root,COG2267@2|Bacteria,2IMQQ@201174|Actinobacteria,4FFD0@85021|Intrasporangiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158463_k127_2778411_10	1089545.KB913037_gene8466	2.262e-21	106.0	2DFS9@1|root,2ZSWU@2|Bacteria,2I7G3@201174|Actinobacteria	201174|Actinobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
SRR25158463_k127_2778411_0	1380370.JIBA01000011_gene3310	2.192e-152	496.0	COG4637@1|root,COG4637@2|Bacteria,2GQVV@201174|Actinobacteria,4FE42@85021|Intrasporangiaceae	201174|Actinobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
SRR25158463_k127_2778411_8	1246995.AFR_10835	3.007e-41	171.0	COG2940@1|root,COG2940@2|Bacteria,2GQAV@201174|Actinobacteria	201174|Actinobacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
SRR25158463_k127_2778411_1	1386089.N865_17140	6.937e-152	490.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4FFBF@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	transporter	araJ	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
SRR25158463_k127_2778411_6	479435.Kfla_3775	2.674e-61	224.0	COG3173@1|root,COG3173@2|Bacteria,2GMHD@201174|Actinobacteria,4DQKS@85009|Propionibacteriales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158463_k127_2778411_11	367299.JOEE01000009_gene263	1.07e-20	94.0	COG2337@1|root,COG2337@2|Bacteria,2GM10@201174|Actinobacteria,4FGCI@85021|Intrasporangiaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
SRR25158463_k127_2780521_7	1386089.N865_15860	8.718e-24	108.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.204	ko:K22307	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
SRR25158463_k127_2780521_0	1386089.N865_15855	9.708e-226	705.0	COG1653@1|root,COG1653@2|Bacteria,2HEYQ@201174|Actinobacteria,4FHU2@85021|Intrasporangiaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
SRR25158463_k127_2780521_4	1386089.N865_15850	1.715e-153	490.0	COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria,4FGZT@85021|Intrasporangiaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158463_k127_2780521_3	1386089.N865_15845	2.417e-175	552.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4FFDG@85021|Intrasporangiaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158463_k127_2780521_1	1386089.N865_15840	2.225e-198	624.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4FE47@85021|Intrasporangiaceae	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
SRR25158463_k127_2780521_6	1172188.KB911820_gene2418	1.446e-69	237.0	COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria,4FGN5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_2780521_5	1386089.N865_10370	1.364e-120	410.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4FFHN@85021|Intrasporangiaceae	201174|Actinobacteria	P	Cytochrome C oxidase assembly protein	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158463_k127_2783511_4	292.DM42_6167	8.222e-24	102.0	COG5485@1|root,COG5485@2|Bacteria,1RIK8@1224|Proteobacteria,2W306@28216|Betaproteobacteria,1K8KK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158463_k127_2783511_1	2045.KR76_05635	2.327e-119	387.0	COG3340@1|root,COG3340@2|Bacteria,2GZK5@201174|Actinobacteria,4DR89@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158463_k127_2783511_3	266940.Krad_1877	1.911e-56	211.0	COG0545@1|root,COG0545@2|Bacteria,2IHQC@201174|Actinobacteria	201174|Actinobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkbP	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SRR25158463_k127_2783511_0	485913.Krac_12078	1.399e-165	543.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Pro-kuma_activ
SRR25158463_k127_2783511_2	1121017.AUFG01000035_gene714	1.162e-111	371.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4FFEG@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158463_k127_2789026_39	253839.SSNG_00097	2.684e-06	51.0	2BVSZ@1|root,32QY7@2|Bacteria,2IJM7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2789026_7	1193181.BN10_680082	1.027e-114	385.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4FIWM@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158463_k127_2789026_36	2045.KR76_27485	1.565e-09	70.0	COG0265@1|root,COG1716@1|root,COG0265@2|Bacteria,COG1716@2|Bacteria,2ICK1@201174|Actinobacteria,4DTQ0@85009|Propionibacteriales	201174|Actinobacteria	OT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FHA,Trypsin_2
SRR25158463_k127_2789026_23	1125973.JNLC01000014_gene2478	1.436e-42	166.0	COG0500@1|root,COG2226@2|Bacteria,1N5QH@1224|Proteobacteria,2UM5M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158463_k127_2789026_17	710687.KI912270_gene3170	3.194e-63	226.0	COG3651@1|root,COG3651@2|Bacteria,2IHNI@201174|Actinobacteria,2396K@1762|Mycobacteriaceae	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
SRR25158463_k127_2789026_20	1206733.BAGC01000068_gene4479	4.615e-53	191.0	COG3832@1|root,COG3832@2|Bacteria,2IRUM@201174|Actinobacteria,4G0SZ@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_2789026_30	298654.FraEuI1c_2468	2.736e-29	122.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria,4EWSM@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158463_k127_2789026_26	479434.Sthe_2969	1.029e-35	142.0	COG0262@1|root,COG0262@2|Bacteria,2G8M0@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_2789026_10	561229.Dd1591_2777	3.093e-101	340.0	COG2162@1|root,COG2162@2|Bacteria	2|Bacteria	Q	arylamine N-acetyltransferase activity	nat	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR25158463_k127_2789026_3	1122138.AQUZ01000016_gene272	5.146e-151	495.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4DPK2@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
SRR25158463_k127_2789026_4	543632.JOJL01000008_gene5922	6.257e-144	472.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4DBU4@85008|Micromonosporales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158463_k127_2789026_9	1122609.AUGT01000005_gene1843	3.49e-106	351.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,4DRD1@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158463_k127_2789026_25	1035308.AQYY01000002_gene670	2.392e-38	152.0	COG3976@1|root,COG3976@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
SRR25158463_k127_2789026_1	1306174.JODP01000011_gene6846	1.162e-201	640.0	COG1018@1|root,COG1018@2|Bacteria,2HE37@201174|Actinobacteria	201174|Actinobacteria	C	Ferric reductase domain protein transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Ferric_reduct,NAD_binding_1
SRR25158463_k127_2789026_8	1032480.MLP_26860	1.123e-114	377.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4DQF3@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	cyeA	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158463_k127_2789026_6	500153.JOEK01000009_gene4745	1.817e-124	414.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158463_k127_2789026_31	471870.BACINT_03021	5.428e-19	99.0	COG4225@1|root,COG4225@2|Bacteria,4NHK7@976|Bacteroidetes,2FPVZ@200643|Bacteroidia,4AP4K@815|Bacteroidaceae	976|Bacteroidetes	S	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
SRR25158463_k127_2789026_14	1463856.JOHY01000017_gene5742	9.685e-79	279.0	COG4948@1|root,COG4948@2|Bacteria,2H17U@201174|Actinobacteria	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158463_k127_2789026_27	1209984.BN978_03404	1.452e-34	148.0	COG3386@1|root,COG3386@2|Bacteria,2GNV1@201174|Actinobacteria,238EU@1762|Mycobacteriaceae	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158463_k127_2789026_32	1116369.KB890024_gene2244	3.049e-16	85.0	COG5517@1|root,COG5517@2|Bacteria,1PYWV@1224|Proteobacteria,2UZWK@28211|Alphaproteobacteria,43QK1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158463_k127_2789026_22	665950.HMPREF1025_01052	6.86e-46	187.0	COG1653@1|root,COG1653@2|Bacteria,1V67U@1239|Firmicutes,24M7B@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158463_k127_2789026_15	411460.RUMTOR_01200	3.516e-68	246.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,249MK@186801|Clostridia,3XZBN@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158463_k127_2789026_16	469383.Cwoe_0376	7.452e-66	247.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10119	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
SRR25158463_k127_2789026_35	158190.SpiGrapes_2415	3.982e-13	84.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	dexB	-	2.4.1.7,3.2.1.20,3.2.1.51,3.2.1.70,3.2.1.93,3.2.1.97	ko:K00690,ko:K01187,ko:K01206,ko:K01215,ko:K01226,ko:K17624	ko00052,ko00500,ko00511,ko01100,map00052,map00500,map00511,map01100	-	R00028,R00801,R00802,R00803,R00837,R06087,R06088,R06113	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000,ko04147	-	GH101,GH13,GH29,GH31	-	Alpha-amylase,Alpha_L_fucos,CBM_35,F5_F8_type_C,NPCBM_assoc,SLH
SRR25158463_k127_2789026_37	1007105.PT7_3047	1.096e-08	65.0	COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,2W6EW@28216|Betaproteobacteria,3T89S@506|Alcaligenaceae	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158463_k127_2789026_24	1502724.FF80_01336	1.459e-39	171.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2TRE1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158463_k127_2789026_21	762376.AXYL_05387	1.303e-50	202.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2VNHN@28216|Betaproteobacteria,3T23A@506|Alcaligenaceae	28216|Betaproteobacteria	K	UTRA	-	-	-	ko:K03486,ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158463_k127_2789026_19	1123023.JIAI01000003_gene2553	2.59e-59	226.0	COG1028@1|root,COG1028@2|Bacteria,2I8VN@201174|Actinobacteria,4E9F8@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_2789026_11	471853.Bcav_0122	1.237e-98	330.0	COG1028@1|root,COG1028@2|Bacteria,2H0SM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100,1.1.1.401	ko:K00059,ko:K21883	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11339,R11671	RC00029,RC00089,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_2789026_28	105420.BBPO01000005_gene2817	3.412e-30	124.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,2NJ2V@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2789026_12	1121952.ATXT01000015_gene312	2.731e-86	299.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4FN9N@85023|Microbacteriaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	pepA	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158463_k127_2789026_0	1032480.MLP_04550	0.0	1106.0	COG0366@1|root,COG0366@2|Bacteria,2GPF3@201174|Actinobacteria,4DTH6@85009|Propionibacteriales	201174|Actinobacteria	G	trehalose synthase	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
SRR25158463_k127_2789026_5	1110697.NCAST_27_00170	3.286e-127	426.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria,4FWAW@85025|Nocardiaceae	201174|Actinobacteria	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158463_k127_2789026_29	1122609.AUGT01000010_gene3741	3.694e-30	126.0	COG3391@1|root,COG3391@2|Bacteria,2H6RD@201174|Actinobacteria,4DWBM@85009|Propionibacteriales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2789026_2	1458357.BG58_18830	1.513e-165	538.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,2VMJU@28216|Betaproteobacteria	28216|Betaproteobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158463_k127_2789026_38	479431.Namu_4547	8.622e-08	60.0	COG0346@1|root,COG0346@2|Bacteria,2IPA6@201174|Actinobacteria,4EW05@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2789026_33	479431.Namu_4547	4.545e-16	90.0	COG0346@1|root,COG0346@2|Bacteria,2IPA6@201174|Actinobacteria,4EW05@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2789026_34	479431.Namu_0374	2.869e-15	84.0	COG0346@1|root,COG0346@2|Bacteria,2IPA6@201174|Actinobacteria,4EW05@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2789026_40	479431.Namu_4548	1.629e-05	48.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EUMV@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
SRR25158463_k127_2789026_41	944560.HMPREF9058_1140	0.0001803	47.0	2ASAU@1|root,31HQ1@2|Bacteria,2HM9N@201174|Actinobacteria,4D6KZ@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2789026_13	471853.Bcav_3294	6.713e-83	291.0	29XIJ@1|root,30J9H@2|Bacteria,2I6JK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2791510_1	1211815.CBYP010000044_gene387	1.202e-105	349.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158463_k127_2791510_5	1121924.ATWH01000005_gene2812	1.014e-72	276.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4FMEB@85023|Microbacteriaceae	201174|Actinobacteria	GM	ABC-2 type transporter	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158463_k127_2791510_4	1128421.JAGA01000002_gene1063	8.893e-79	274.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158463_k127_2791510_10	1211035.CD30_13805	3.79e-39	162.0	COG0500@1|root,COG0500@2|Bacteria,1UN2E@1239|Firmicutes	1239|Firmicutes	Q	Methionine biosynthesis protein MetW	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	MetW,Methyltransf_23
SRR25158463_k127_2791510_6	1280681.AUJZ01000024_gene3602	8.091e-70	253.0	COG0438@1|root,COG0438@2|Bacteria,1TQRV@1239|Firmicutes,24E7I@186801|Clostridia,4BYRD@830|Butyrivibrio	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158463_k127_2791510_9	1235835.C814_02338	8.565e-47	194.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_2
SRR25158463_k127_2791510_2	1193181.BN10_520061	6.509e-99	335.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,4FF5E@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_2791510_0	1193181.BN10_520058	7.942e-106	361.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,4FF5E@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_2791510_8	1206741.BAFX01000002_gene5629	5.141e-66	242.0	COG1835@1|root,COG1835@2|Bacteria,2I96Z@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158463_k127_2791510_3	1385521.N803_02465	6.527e-96	322.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4FEPF@85021|Intrasporangiaceae	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158463_k127_2791510_7	351607.Acel_0417	1.81e-66	240.0	COG3858@1|root,COG5479@1|root,COG3858@2|Bacteria,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4ESE3@85013|Frankiales	201174|Actinobacteria	M	Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme.	csp	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP
SRR25158463_k127_2799442_2	1121017.AUFG01000022_gene2211	5.827e-149	491.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4FE4H@85021|Intrasporangiaceae	201174|Actinobacteria	S	permease	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158463_k127_2799442_12	1380370.JIBA01000019_gene972	3.863e-25	106.0	2DSCZ@1|root,33FKC@2|Bacteria,2GR4J@201174|Actinobacteria,4FHV6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2530)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2530
SRR25158463_k127_2799442_8	710696.Intca_0738	1.548e-103	346.0	28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4FENM@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3027)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3027
SRR25158463_k127_2799442_10	471852.Tcur_0818	2.926e-41	158.0	COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4EJAV@85012|Streptosporangiales	201174|Actinobacteria	K	Cold shock protein domain	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158463_k127_2799442_7	1385521.N803_04110	3.421e-115	378.0	COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4FERV@85021|Intrasporangiaceae	201174|Actinobacteria	G	galactose mutarotase	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158463_k127_2799442_13	1385521.N803_11460	1.177e-10	70.0	2DRJD@1|root,33C0U@2|Bacteria,2GUMW@201174|Actinobacteria,4FHQC@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2799442_1	710696.Intca_0735	1.354e-238	767.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria,4FEKN@85021|Intrasporangiaceae	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
SRR25158463_k127_2799442_3	1386089.N865_21385	1.768e-143	494.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4FEHD@85021|Intrasporangiaceae	201174|Actinobacteria	E	Hydroxymethylglutaryl-CoA lyase	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158463_k127_2799442_0	1121017.AUFG01000038_gene826	1.78e-317	976.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4FFDM@85021|Intrasporangiaceae	201174|Actinobacteria	L	Helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR25158463_k127_2799442_9	710696.Intca_2218	6.243e-71	248.0	2E5FQ@1|root,3307E@2|Bacteria,2INDB@201174|Actinobacteria,4FJME@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2799442_5	266940.Krad_0908	2.135e-129	435.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158463_k127_2799442_6	1385520.N802_06455	4.86e-116	385.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4FE6S@85021|Intrasporangiaceae	201174|Actinobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_2799442_4	1386089.N865_21405	2.735e-142	478.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4FFK1@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158463_k127_2799442_11	1386089.N865_21410	5.894e-26	120.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4FEHF@85021|Intrasporangiaceae	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	degP	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158463_k127_2808104_7	313589.JNB_10084	1.566e-31	126.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4FGP9@85021|Intrasporangiaceae	201174|Actinobacteria	J	LysR family transcriptional regulator	yabJ	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158463_k127_2808104_8	313589.JNB_10089	3.199e-27	110.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,4FHQA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158463_k127_2808104_5	397278.JOJN01000007_gene3199	1.28e-35	147.0	COG3247@1|root,COG3247@2|Bacteria,2I06M@201174|Actinobacteria,4DVZJ@85009|Propionibacteriales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158463_k127_2808104_3	110319.CF8_3148	1.495e-60	223.0	COG3185@1|root,COG3185@2|Bacteria,2GIYF@201174|Actinobacteria,4DWYA@85009|Propionibacteriales	201174|Actinobacteria	E	4-Hydroxyphenylpyruvate dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2808104_4	1386089.N865_17770	5.205e-60	215.0	COG1506@1|root,COG1506@2|Bacteria,2I3Z4@201174|Actinobacteria,4FFYZ@85021|Intrasporangiaceae	201174|Actinobacteria	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6,Peptidase_S9
SRR25158463_k127_2808104_1	1386089.N865_17780	8.336e-127	413.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,4FFN1@85021|Intrasporangiaceae	201174|Actinobacteria	D	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158463_k127_2808104_0	1380370.JIBA01000003_gene2684	1.563e-167	535.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4FFB0@85021|Intrasporangiaceae	201174|Actinobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158463_k127_2808104_6	1089455.MOPEL_020_00270	7.351e-34	135.0	2CC1Y@1|root,32TCV@2|Bacteria,2IQEP@201174|Actinobacteria,4F749@85018|Dermatophilaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	wblA	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158463_k127_2808104_2	710696.Intca_0469	4.472e-126	414.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4FERW@85021|Intrasporangiaceae	201174|Actinobacteria	M	Penicillin-binding Protein	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
SRR25158463_k127_2834283_19	1184609.KILIM_001_00170	7.591e-60	228.0	COG0001@1|root,COG0001@2|Bacteria,2GKJV@201174|Actinobacteria,4F7HP@85018|Dermatophilaceae	201174|Actinobacteria	H	C-methyltransferase C-terminal domain	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158463_k127_2834283_16	1380393.JHVP01000008_gene4705	1.912e-66	243.0	COG2120@1|root,COG2120@2|Bacteria,2GMXC@201174|Actinobacteria,4EW14@85013|Frankiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158463_k127_2834283_6	1122609.AUGT01000008_gene2875	3.568e-138	444.0	COG1208@1|root,COG1208@2|Bacteria,2GKHA@201174|Actinobacteria	201174|Actinobacteria	JM	Glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SRR25158463_k127_2834283_1	1380356.JNIK01000004_gene191	3.336e-199	642.0	COG2230@1|root,COG2230@2|Bacteria,2I3YR@201174|Actinobacteria,4EXH0@85013|Frankiales	201174|Actinobacteria	M	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SRR25158463_k127_2834283_3	1380393.JHVP01000008_gene4703	7.891e-163	518.0	COG0451@1|root,COG0451@2|Bacteria,2GNYX@201174|Actinobacteria,4ETSW@85013|Frankiales	201174|Actinobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158463_k127_2834283_13	1172180.KB911778_gene4847	1.752e-79	271.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158463_k127_2834283_5	479432.Sros_0640	1.726e-140	460.0	2ART5@1|root,2ZK1C@2|Bacteria,2IAHA@201174|Actinobacteria,4EMID@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2834283_4	1122609.AUGT01000008_gene2869	1.065e-152	499.0	COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,4DUU7@85009|Propionibacteriales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	-	ko:K03328,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.7	-	-	Polysacc_synt_3,Polysacc_synt_C
SRR25158463_k127_2834283_14	479432.Sros_0642	2.352e-75	281.0	COG0463@1|root,COG0463@2|Bacteria,2HEJH@201174|Actinobacteria,4ENNS@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158463_k127_2834283_12	1121946.AUAX01000009_gene4352	2.577e-84	301.0	COG3307@1|root,COG3307@2|Bacteria,2ICRB@201174|Actinobacteria,4DB4R@85008|Micromonosporales	201174|Actinobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158463_k127_2834283_22	1158050.KB895461_gene2911	9.268e-31	135.0	COG3206@1|root,COG3206@2|Bacteria,2IIGS@201174|Actinobacteria	201174|Actinobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2834283_18	1159870.KB907784_gene1557	2.977e-60	222.0	2DUFP@1|root,33QF7@2|Bacteria,1NU95@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2834283_7	1121946.AUAX01000009_gene4363	2.855e-125	424.0	2EE91@1|root,3383F@2|Bacteria,2IAWN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2834283_23	1123248.KB893316_gene4600	1.962e-22	113.0	COG1749@1|root,COG3055@1|root,COG1749@2|Bacteria,COG3055@2|Bacteria,4NTUT@976|Bacteroidetes	976|Bacteroidetes	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4082
SRR25158463_k127_2834283_10	1386089.N865_09940	4.103e-90	301.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4FE5Y@85021|Intrasporangiaceae	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158463_k127_2834283_11	1385520.N802_15495	1.085e-88	299.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4FE4J@85021|Intrasporangiaceae	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158463_k127_2834283_9	479431.Namu_5292	9.321e-95	321.0	COG0697@1|root,COG0697@2|Bacteria,2GKVT@201174|Actinobacteria,4EU7S@85013|Frankiales	201174|Actinobacteria	EG	EamA-like transporter family	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158463_k127_2834283_15	479431.Namu_5293	8.097e-69	238.0	COG5516@1|root,COG5516@2|Bacteria,2GNZF@201174|Actinobacteria,4EVK4@85013|Frankiales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158463_k127_2834283_2	1172188.KB911825_gene3754	8.409e-181	570.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4FE7Y@85021|Intrasporangiaceae	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158463_k127_2834283_0	1380370.JIBA01000016_gene871	8.837e-211	664.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4FEQE@85021|Intrasporangiaceae	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158463_k127_2834283_21	1032480.MLP_26920	3.435e-43	163.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4DRFG@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158463_k127_2834283_8	935866.JAER01000009_gene747	1.699e-113	372.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DNPK@85009|Propionibacteriales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158463_k127_2834283_17	2045.KR76_18825	2.544e-66	236.0	COG0580@1|root,COG0580@2|Bacteria,2GMG4@201174|Actinobacteria,4DQ3S@85009|Propionibacteriales	201174|Actinobacteria	G	Major intrinsic protein	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	MIP
SRR25158463_k127_2834283_20	710111.FraQA3DRAFT_1284	1.875e-52	201.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4ET2T@85013|Frankiales	201174|Actinobacteria	T	low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158463_k127_2834922_2	479431.Namu_4198	3.995e-122	400.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4ERK7@85013|Frankiales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158463_k127_2834922_0	1380370.JIBA01000016_gene703	1.043e-194	624.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4FEGS@85021|Intrasporangiaceae	201174|Actinobacteria	GM	dtdp-glucose 4,6-dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
SRR25158463_k127_2834922_1	1172188.KB911825_gene3582	4.21e-130	451.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4FFKS@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158463_k127_2834922_4	188626.HMPREF0321_2001	2.832e-74	272.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,1ZWG3@145357|Dermacoccaceae	201174|Actinobacteria	M	Bacterial sugar transferase	epsL	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
SRR25158463_k127_2834922_5	1385520.N802_16540	8.813e-70	253.0	COG0110@1|root,COG0110@2|Bacteria,2IDUP@201174|Actinobacteria	201174|Actinobacteria	GM	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
SRR25158463_k127_2834922_3	479435.Kfla_2274	2.829e-120	391.0	COG1357@1|root,COG1357@2|Bacteria,2GN74@201174|Actinobacteria,4DNE2@85009|Propionibacteriales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Pentapeptide
SRR25158463_k127_285631_1	367299.JOEE01000003_gene2677	1.959e-159	506.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4FEFA@85021|Intrasporangiaceae	201174|Actinobacteria	D	Cell division protein FtsK	ftsK	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158463_k127_285631_2	1380354.JIAN01000009_gene3650	1.549e-146	469.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4F328@85016|Cellulomonadaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158463_k127_285631_0	1122611.KB904007_gene7760	1.566e-227	720.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4EFHH@85012|Streptosporangiales	201174|Actinobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158463_k127_2860511_3	710421.Mycch_3127	9.144e-119	383.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,2331T@1762|Mycobacteriaceae	201174|Actinobacteria	E	Methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158463_k127_2860511_1	1172188.KB911823_gene525	1.303e-123	406.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,4FFDN@85021|Intrasporangiaceae	201174|Actinobacteria	L	Domain of unknown function DUF83	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158463_k127_2860511_6	1385521.N803_08190	3.855e-83	289.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4FF3W@85021|Intrasporangiaceae	201174|Actinobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158463_k127_2860511_2	1306174.JODP01000002_gene5748	8.223e-121	398.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158463_k127_2860511_0	1172188.KB911823_gene512	1.063e-174	556.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,4FEEX@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
SRR25158463_k127_2860511_4	710696.Intca_1752	1.559e-100	334.0	COG5032@1|root,COG5032@2|Bacteria,2GME7@201174|Actinobacteria,4FGSC@85021|Intrasporangiaceae	201174|Actinobacteria	BDLTU	Phosphatidylinositol 3-and 4-kinase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2860511_7	1380370.JIBA01000013_gene1469	3.959e-61	215.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4FGZE@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158463_k127_2860511_5	1172188.KB911823_gene509	1.074e-87	295.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,4FGE9@85021|Intrasporangiaceae	201174|Actinobacteria	G	phosphoglycerate mutase	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SRR25158463_k127_2860511_8	1386089.N865_07885	5.174e-33	129.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4FER1@85021|Intrasporangiaceae	201174|Actinobacteria	P	Magnesium	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158463_k127_2892709_4	67275.JOAP01000008_gene4055	2.318e-15	83.0	2E23Z@1|root,32XB8@2|Bacteria,2GN8H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2892709_3	66377.JOBH01000004_gene3661	3.015e-92	308.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria	201174|Actinobacteria	C	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158463_k127_2892709_2	66377.JOBH01000004_gene3660	1.228e-112	381.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
SRR25158463_k127_2892709_0	1380370.JIBA01000014_gene1724	6.899e-247	768.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4FERY@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158463_k127_2892709_1	1120949.KB903339_gene8028	2.901e-186	592.0	COG1653@1|root,COG1653@2|Bacteria,2GZ1E@201174|Actinobacteria,4DCHT@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158463_k127_2907657_3	446466.Cfla_2372	1.056e-08	61.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158463_k127_2907657_1	479435.Kfla_0530	1.315e-93	319.0	COG0500@1|root,COG2226@2|Bacteria,2IEHC@201174|Actinobacteria,4DVJ2@85009|Propionibacteriales	201174|Actinobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158463_k127_2907657_0	479435.Kfla_0529	2.321e-97	326.0	COG0463@1|root,COG0463@2|Bacteria,2I67S@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158463_k127_2907657_2	1283299.AUKG01000001_gene2289	1.769e-45	189.0	COG4485@1|root,COG4485@2|Bacteria,2IKI5@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2914300_2	1380370.JIBA01000013_gene1268	6.466e-68	235.0	COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria,4FGIY@85021|Intrasporangiaceae	201174|Actinobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2914300_0	1123024.AUII01000002_gene889	0.0	1270.0	COG3899@1|root,COG3899@2|Bacteria,2HETF@201174|Actinobacteria,4EBUT@85010|Pseudonocardiales	201174|Actinobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2914300_3	479431.Namu_4547	6.042e-62	222.0	COG0346@1|root,COG0346@2|Bacteria,2IPA6@201174|Actinobacteria,4EW05@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2914300_1	1448389.BAVQ01000009_gene3894	3.31e-102	348.0	COG0596@1|root,COG0596@2|Bacteria,2GMYM@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158463_k127_2931072_7	1385521.N803_00150	2.862e-46	185.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4FEBG@85021|Intrasporangiaceae	201174|Actinobacteria	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158463_k127_2931072_2	313589.JNB_04455	5.206e-165	548.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4FFMU@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158463_k127_2931072_1	1172188.KB911824_gene3475	2.429e-226	711.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4FESE@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158463_k127_2931072_5	1172188.KB911821_gene1470	1.212e-126	421.0	COG1403@1|root,COG1403@2|Bacteria,2I9AH@201174|Actinobacteria,4FG65@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158463_k127_2931072_8	1386089.N865_05720	8e-34	135.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,4FH3B@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158463_k127_2931072_4	1123024.AUII01000002_gene1084	1.41e-132	431.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,2I75H@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158463_k127_2931072_3	1380370.JIBA01000011_gene3155	1.222e-150	482.0	COG0189@1|root,COG0189@2|Bacteria,2I8TP@201174|Actinobacteria,4FJAK@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158463_k127_2931072_0	710696.Intca_1537	4.378e-273	865.0	COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4FF4B@85021|Intrasporangiaceae	201174|Actinobacteria	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158463_k127_2931072_6	710696.Intca_1532	1.863e-70	248.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4FG6S@85021|Intrasporangiaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158463_k127_2947166_0	313589.JNB_17153	0.0	1763.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4FF0B@85021|Intrasporangiaceae	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158463_k127_2947166_3	710696.Intca_0929	6.622e-13	77.0	COG0760@1|root,COG0760@2|Bacteria,2IHAH@201174|Actinobacteria,4FGH0@85021|Intrasporangiaceae	201174|Actinobacteria	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2947166_2	710696.Intca_0930	3.597e-108	379.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4FF48@85021|Intrasporangiaceae	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SRR25158463_k127_2947166_1	367299.JOEE01000007_gene175	2.351e-233	728.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4FE8B@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158463_k127_2955026_1	1386089.N865_17505	1.798e-146	466.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4FEQU@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dihydrolipoyl dehydrogenase	lpd	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158463_k127_2955026_5	644283.Micau_2759	1.147e-84	287.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4D8MM@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158463_k127_2955026_7	1385520.N802_11735	1.889e-43	173.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria,4FH8D@85021|Intrasporangiaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2955026_9	1184609.KILIM_007_00480	1.078e-22	102.0	COG0225@1|root,COG0225@2|Bacteria,2GWWD@201174|Actinobacteria	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2955026_10	105425.BBPL01000059_gene5083	7.783e-15	83.0	29345@1|root,2ZQM9@2|Bacteria,2HECD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2955026_2	1120954.ATXE01000003_gene654	2.698e-126	425.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4DSXI@85009|Propionibacteriales	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158463_k127_2955026_3	1394178.AWOO02000002_gene1753	4.913e-111	364.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158463_k127_2955026_8	1120954.ATXE01000003_gene653	1.629e-40	154.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	yabJ	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158463_k127_2955026_0	1394178.AWOO02000002_gene1765	4.283e-152	502.0	COG0001@1|root,COG0001@2|Bacteria,2IBG2@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158463_k127_2955026_4	1394178.AWOO02000002_gene1762	1.216e-88	301.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158463_k127_2955026_6	1449353.JQMQ01000005_gene2423	2.541e-70	242.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,2NETU@228398|Streptacidiphilus	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158463_k127_2975749_9	1385520.N802_19290	7.159e-07	52.0	COG1611@1|root,COG1611@2|Bacteria,2GPA4@201174|Actinobacteria,4FETS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Rossmann fold nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
SRR25158463_k127_2975749_0	1386089.N865_10065	1.73e-321	995.0	COG0365@1|root,COG0365@2|Bacteria,2GP7N@201174|Actinobacteria,4FEXP@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158463_k127_2975749_3	1386089.N865_10055	3.468e-98	329.0	COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4FE7Z@85021|Intrasporangiaceae	201174|Actinobacteria	S	transport integral membrane protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
SRR25158463_k127_2975749_4	479433.Caci_5538	2.151e-74	253.0	2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2975749_8	10228.TriadP19424	1.671e-07	63.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa	33208|Metazoa	T	lipoprotein receptor-related protein	-	-	-	ko:K03068,ko:K20051	ko04150,ko04310,ko05200,ko05224,ko05225,ko05226,map04150,map04310,map05200,map05224,map05225,map05226	-	-	-	ko00000,ko00001,ko04131	-	-	-	FXa_inhibition,Ldl_recept_a,Ldl_recept_b
SRR25158463_k127_2975749_6	1380370.JIBA01000012_gene3763	2.754e-61	214.0	COG2867@1|root,COG2867@2|Bacteria,2IIFW@201174|Actinobacteria	201174|Actinobacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158463_k127_2975749_7	1386089.N865_11250	4.645e-59	225.0	COG2318@1|root,COG2318@2|Bacteria,2GK59@201174|Actinobacteria,4FGRZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158463_k127_2975749_1	1380370.JIBA01000014_gene1864	1.202e-267	832.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FE6A@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158463_k127_2975749_5	367299.JOEE01000004_gene1206	1.662e-67	233.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4FGCJ@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158463_k127_2975749_2	1380370.JIBA01000014_gene1862	3.709e-190	598.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FFRV@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158463_k127_2978169_0	1172188.KB911823_gene465	1.105e-203	642.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FFUG@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_2978169_6	1298863.AUEP01000004_gene2025	6.207e-53	188.0	COG0346@1|root,COG0346@2|Bacteria,2HKQB@201174|Actinobacteria,4DSSY@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_2978169_5	1121017.AUFG01000001_gene3098	6.702e-85	295.0	COG1024@1|root,COG1024@2|Bacteria,2GKC4@201174|Actinobacteria,4FFWD@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158463_k127_2978169_7	2074.JNYD01000001_gene5910	4.011e-40	163.0	COG4106@1|root,COG4106@2|Bacteria,2I3QF@201174|Actinobacteria,4E20K@85010|Pseudonocardiales	201174|Actinobacteria	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158463_k127_2978169_3	1101188.KI912155_gene997	1.201e-117	403.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,2GK3B@201174|Actinobacteria,1W89C@1268|Micrococcaceae	201174|Actinobacteria	H	Siroheme synthase	cobA	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
SRR25158463_k127_2978169_1	1894.JOER01000006_gene887	1.15e-162	526.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
SRR25158463_k127_2978169_2	1003195.SCAT_4726	2.116e-123	397.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria	201174|Actinobacteria	EH	sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158463_k127_2978169_8	67332.FM21_19705	1.178e-34	144.0	COG0175@1|root,COG0175@2|Bacteria,2GN85@201174|Actinobacteria	201174|Actinobacteria	EH	sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158463_k127_2978169_4	1210046.B277_09782	3.329e-112	367.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4FEUD@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158463_k127_2981104_5	1386089.N865_10310	5.558e-61	211.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4FF05@85021|Intrasporangiaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158463_k127_2981104_3	1385518.N798_09280	1.802e-115	379.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4FEQ4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158463_k127_2981104_2	1380370.JIBA01000014_gene1913	7.551e-238	743.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4FE69@85021|Intrasporangiaceae	201174|Actinobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iNJ661.Rv2920c	Ammonium_transp
SRR25158463_k127_2981104_6	1386089.N865_10300	2.607e-60	211.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4FH1F@85021|Intrasporangiaceae	201174|Actinobacteria	K	at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA)	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158463_k127_2981104_0	1386089.N865_10295	0.0	1095.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4FF82@85021|Intrasporangiaceae	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158463_k127_2981104_1	1386089.N865_10290	1.366e-275	854.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4FEYZ@85021|Intrasporangiaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158463_k127_2981104_4	1172188.KB911821_gene1769	4.29e-92	314.0	2EX3R@1|root,33QES@2|Bacteria,2GMEF@201174|Actinobacteria,4FK1Y@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_2981104_7	1349820.M707_11010	4.537e-14	72.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria,1WA93@1268|Micrococcaceae	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158463_k127_2984153_1	1386089.N865_13080	9.836e-178	562.0	COG0462@1|root,COG0462@2|Bacteria,2GKR2@201174|Actinobacteria,4FFIH@85021|Intrasporangiaceae	201174|Actinobacteria	EF	Ribose-phosphate pyrophosphokinase	prs_1	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158463_k127_2984153_0	1172188.KB911823_gene534	9.836e-230	720.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4FEJ9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pup deamidase depupylase	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158463_k127_2984153_5	1386089.N865_13095	8.763e-20	90.0	2E9C2@1|root,333JS@2|Bacteria,2IQ5V@201174|Actinobacteria,4FHFW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR25158463_k127_2984153_2	313589.JNB_02960	5.645e-127	413.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4FE8W@85021|Intrasporangiaceae	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158463_k127_2984153_3	710696.Intca_1771	1.471e-114	387.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4FFJS@85021|Intrasporangiaceae	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158463_k127_2984153_4	1463881.KL591003_gene5793	9.687e-68	235.0	COG0386@1|root,COG0386@2|Bacteria,2IFJH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SRR25158463_k127_2992020_7	1386089.N865_04555	1.611e-16	83.0	COG0169@1|root,COG0169@2|Bacteria,2GPXV@201174|Actinobacteria,4FGPA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0030266,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N,ThiF
SRR25158463_k127_2992020_0	1386089.N865_04550	8.457e-209	677.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4FG3K@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_2992020_1	1386089.N865_04545	6.575e-149	478.0	COG1609@1|root,COG1609@2|Bacteria,2GMUU@201174|Actinobacteria,4FJV3@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_2992020_4	1298863.AUEP01000008_gene1284	8.154e-106	349.0	COG1414@1|root,COG1414@2|Bacteria,2I9CD@201174|Actinobacteria,4DNST@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158463_k127_2992020_2	1033730.CAHG01000005_gene925	1.019e-148	473.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,4DWNH@85009|Propionibacteriales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
SRR25158463_k127_2992020_6	1223544.GSI01S_51_00050	1.877e-74	255.0	COG3485@1|root,COG3485@2|Bacteria,2GZGT@201174|Actinobacteria,4GDT0@85026|Gordoniaceae	201174|Actinobacteria	Q	Dioxygenase	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158463_k127_2992020_3	1869.MB27_37125	6.071e-131	438.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4DE9H@85008|Micromonosporales	201174|Actinobacteria	F	Lyase	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158463_k127_2992020_5	1033730.CAHG01000005_gene928	1.088e-75	277.0	COG0599@1|root,COG2267@1|root,COG0599@2|Bacteria,COG2267@2|Bacteria,2GITB@201174|Actinobacteria,4DPVA@85009|Propionibacteriales	201174|Actinobacteria	I	Carboxymuconolactone decarboxylase family	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
SRR25158463_k127_3003841_2	1121385.AQXW01000003_gene358	4.629e-17	80.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,1ZW4B@145357|Dermacoccaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158463_k127_3003841_1	1386089.N865_13330	9.986e-199	630.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4FE8I@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
SRR25158463_k127_3003841_0	1386089.N865_13335	0.0	2132.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4FG36@85021|Intrasporangiaceae	201174|Actinobacteria	E	Dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158463_k127_30432_13	749414.SBI_09436	9.336e-18	88.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,NUDIX,TP_methylase
SRR25158463_k127_30432_9	290399.Arth_0447	2.106e-108	357.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158463_k127_30432_0	1385520.N802_01545	0.0	1086.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4FET8@85021|Intrasporangiaceae	201174|Actinobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
SRR25158463_k127_30432_5	1380370.JIBA01000012_gene3550	3.091e-142	481.0	COG0531@1|root,COG0531@2|Bacteria,2IAK1@201174|Actinobacteria,4FFNR@85021|Intrasporangiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13	-	-	AA_permease_2
SRR25158463_k127_30432_3	1120949.KB903308_gene1206	2.375e-149	497.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4D9NI@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158463_k127_30432_1	397278.JOJN01000006_gene1125	2.057e-293	942.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2HEZR@201174|Actinobacteria,4DV1I@85009|Propionibacteriales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
SRR25158463_k127_30432_7	397278.JOJN01000006_gene1124	1.56e-122	410.0	COG0664@1|root,COG0664@2|Bacteria,2ID3H@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158463_k127_30432_8	2074.JNYD01000027_gene7337	4.757e-120	399.0	COG0025@1|root,COG0025@2|Bacteria,2GKCK@201174|Actinobacteria,4E43Y@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158463_k127_30432_4	479431.Namu_5258	2.102e-147	475.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ES16@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter	-	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
SRR25158463_k127_30432_10	1380356.JNIK01000013_gene4259	3.447e-103	358.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4EUNE@85013|Frankiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K18233	ko02010,map02010	M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1.105.2	-	-	ABC2_membrane
SRR25158463_k127_30432_2	479431.Namu_5260	4.996e-259	835.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4ETGG@85013|Frankiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158463_k127_30432_11	1385518.N798_06535	1.935e-63	220.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria,4FGVJ@85021|Intrasporangiaceae	201174|Actinobacteria	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158463_k127_30432_12	1210046.B277_05648	2.903e-62	222.0	2DQ1M@1|root,32UNB@2|Bacteria,2I0BJ@201174|Actinobacteria,4FH36@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_30432_6	1385519.N801_14925	1.517e-136	455.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4FGFJ@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3077677_4	1172188.KB911820_gene2993	1.342e-70	258.0	COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria,4FF6I@85021|Intrasporangiaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158463_k127_3077677_8	395495.Lcho_4089	1.591e-34	147.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2VS1N@28216|Betaproteobacteria,1KPBG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SRR25158463_k127_3077677_0	930171.Asphe3_00570	3.311e-256	810.0	2DB9H@1|root,2Z7WW@2|Bacteria,2I2TQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
SRR25158463_k127_3077677_6	1122138.AQUZ01000050_gene7798	4.334e-63	223.0	COG0500@1|root,COG2226@2|Bacteria,2IMIR@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158463_k127_3077677_7	1386089.N865_10740	6.608e-47	179.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4FGBD@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158463_k127_3077677_3	446466.Cfla_1744	2.725e-90	309.0	COG1305@1|root,COG1305@2|Bacteria,2GMD7@201174|Actinobacteria	201174|Actinobacteria	E	transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158463_k127_3077677_5	208444.JNYY01000028_gene2467	1.639e-70	250.0	COG0500@1|root,COG2226@2|Bacteria,2I3JA@201174|Actinobacteria,4E3WJ@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,NUDIX
SRR25158463_k127_3077677_10	1386089.N865_18795	4.049e-15	78.0	2EIY8@1|root,33CPE@2|Bacteria,2GXKK@201174|Actinobacteria,4FI0G@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3077677_2	1121381.JNIV01000020_gene3260	6.498e-132	435.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
SRR25158463_k127_3077677_9	930171.Asphe3_27240	1.933e-27	117.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3077677_1	1380370.JIBA01000002_gene2669	7.495e-139	450.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria,4FG1F@85021|Intrasporangiaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158463_k127_3094821_4	1032480.MLP_00390	5.743e-50	189.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DNN3@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_3094821_3	1032480.MLP_00400	3.805e-50	181.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria,4DSEC@85009|Propionibacteriales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_3094821_0	1386089.N865_01960	0.0	1787.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4FEPI@85021|Intrasporangiaceae	201174|Actinobacteria	L	ATP-dependent helicase	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
SRR25158463_k127_3094821_2	1380370.JIBA01000017_gene2877	5.628e-133	432.0	COG2047@1|root,COG2047@2|Bacteria,2GK8I@201174|Actinobacteria,4FFY0@85021|Intrasporangiaceae	201174|Actinobacteria	S	Proteasome assembly chaperone 2	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158463_k127_3094821_1	1172188.KB911824_gene3431	8.795e-181	572.0	COG0749@1|root,COG0749@2|Bacteria,2GM8R@201174|Actinobacteria,4FFYJ@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA polymerase I	polA2	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A
SRR25158463_k127_3098769_4	1385519.N801_03260	3.725e-73	252.0	COG5592@1|root,COG5592@2|Bacteria,2IGW0@201174|Actinobacteria,4FG2N@85021|Intrasporangiaceae	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158463_k127_3098769_6	31964.CMS1035	2.808e-39	153.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria,4FPVN@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158463_k127_3098769_7	935839.JAGJ01000005_gene2642	6.958e-39	154.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4F4UG@85017|Promicromonosporaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158463_k127_3098769_8	1172185.KB911513_gene4501	1.189e-29	128.0	COG0711@1|root,COG0711@2|Bacteria,2IQQZ@201174|Actinobacteria,4G70H@85025|Nocardiaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3098769_1	1172188.KB911827_gene4277	5.809e-139	453.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4FF5I@85021|Intrasporangiaceae	201174|Actinobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158463_k127_3098769_5	37919.EP51_03650	4.422e-54	210.0	COG2264@1|root,COG2264@2|Bacteria,2I2PZ@201174|Actinobacteria,4G1BD@85025|Nocardiaceae	201174|Actinobacteria	J	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	NodS
SRR25158463_k127_3098769_2	101510.RHA1_ro00130	1.634e-109	374.0	COG1960@1|root,COG1960@2|Bacteria,2GKK2@201174|Actinobacteria,4FWD6@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158463_k127_3098769_3	1380370.JIBA01000011_gene3257	3.135e-96	341.0	COG0859@1|root,COG0859@2|Bacteria,2GMZG@201174|Actinobacteria	201174|Actinobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158463_k127_3098769_9	1229780.BN381_130247	3.484e-25	117.0	COG1028@1|root,COG1028@2|Bacteria,2GK78@201174|Actinobacteria,3UXCQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_3098769_0	1146883.BLASA_0450	5.643e-145	474.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2GKU1@201174|Actinobacteria,4ETXU@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SRR25158463_k127_3100711_9	1380370.JIBA01000015_gene58	0.0002844	47.0	2ATXX@1|root,31JHF@2|Bacteria,2IJEE@201174|Actinobacteria,4FGUU@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3100711_4	1386089.N865_14850	4.89e-121	410.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4FF22@85021|Intrasporangiaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	sprI	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158463_k127_3100711_8	710696.Intca_2592	1.099e-38	148.0	COG1826@1|root,COG1826@2|Bacteria,2IR0U@201174|Actinobacteria,4FHHW@85021|Intrasporangiaceae	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0008150,GO:0040007	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158463_k127_3100711_0	1386089.N865_14840	1.019e-203	642.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4FEXA@85021|Intrasporangiaceae	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158463_k127_3100711_1	526225.Gobs_2527	4.826e-201	636.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08139	ko04113,map04113	-	-	-	ko00000,ko00001,ko02000	2.A.1.1	-	-	Sugar_tr
SRR25158463_k127_3100711_6	1121385.AQXW01000004_gene1860	1.103e-66	231.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria,1ZW1I@145357|Dermacoccaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158463_k127_3100711_2	1386089.N865_14830	7.101e-182	578.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria,4FF03@85021|Intrasporangiaceae	201174|Actinobacteria	P	transporter	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRR25158463_k127_3100711_7	1172188.KB911821_gene1755	4.496e-58	206.0	2E6WZ@1|root,331GF@2|Bacteria,2IFC6@201174|Actinobacteria,4FGUR@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3100711_3	110319.CF8_3518	4.48e-181	571.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4DP95@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
SRR25158463_k127_3100711_5	1386089.N865_14815	3.692e-119	390.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4FE7E@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	mcl2	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI,PEP-utilizers_C
SRR25158463_k127_310315_1	1385519.N801_17615	3.671e-268	859.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,4FFMG@85021|Intrasporangiaceae	201174|Actinobacteria	G	Maltooligosyl trehalose synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158463_k127_310315_0	1172188.KB911824_gene3276	0.0	1160.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4FFP7@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158463_k127_310315_6	1184609.KILIM_025_00280	1.397e-96	345.0	COG0038@1|root,COG0038@2|Bacteria	2|Bacteria	P	chloride channel	yfeO	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
SRR25158463_k127_310315_5	1283287.KB822579_gene1952	6.393e-119	394.0	COG2267@1|root,COG2267@2|Bacteria,2H83P@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158463_k127_310315_4	1298863.AUEP01000020_gene3569	4.297e-149	482.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4DPN9@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	limB_5	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_310315_3	1121017.AUFG01000031_gene360	5.515e-158	503.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4FEFZ@85021|Intrasporangiaceae	201174|Actinobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158463_k127_310315_2	1386089.N865_06705	3.35e-207	655.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4FE3A@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA4	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158463_k127_310315_7	67267.JNXT01000023_gene4341	9.123e-66	231.0	COG1404@1|root,COG3209@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,2I4QJ@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3112761_3	1386089.N865_02935	3.649e-126	421.0	COG2313@1|root,COG2313@2|Bacteria,2GK19@201174|Actinobacteria,4FEJH@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158463_k127_3112761_1	1386089.N865_02925	2.327e-145	479.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4FEVE@85021|Intrasporangiaceae	201174|Actinobacteria	S	amidohydrolase	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_3112761_2	1386089.N865_02920	1.717e-140	456.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4FG7H@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	bmpA	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158463_k127_3112761_0	1035308.AQYY01000001_gene3639	2e-227	713.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,26098@186807|Peptococcaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158463_k127_3117800_3	1298863.AUEP01000010_gene4505	1.178e-136	450.0	COG0372@1|root,COG0372@2|Bacteria,2H9YP@201174|Actinobacteria,4DSM0@85009|Propionibacteriales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158463_k127_3117800_1	1146883.BLASA_2971	9.558e-195	612.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4ESG3@85013|Frankiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158463_k127_3117800_0	477641.MODMU_3387	2.934e-261	811.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria,4ESKE@85013|Frankiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158463_k127_3117800_4	1211815.CBYP010000066_gene1588	2.382e-121	394.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4ESUU@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158463_k127_3117800_2	1283283.ATXA01000001_gene1208	8.254e-177	569.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4EUEP@85013|Frankiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158463_k127_3117800_5	1265310.CCBD010000050_gene1939	2.234e-05	54.0	COG0515@1|root,COG0515@2|Bacteria,2GSSF@201174|Actinobacteria,239KP@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_312599_0	1121017.AUFG01000011_gene1699	0.0	1120.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4FF4K@85021|Intrasporangiaceae	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158463_k127_312599_1	477641.MODMU_0134	1.221e-253	813.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EU99@85013|Frankiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_312599_4	1464048.JNZS01000001_gene79	1.997e-29	122.0	COG1846@1|root,COG1846@2|Bacteria,2IHP0@201174|Actinobacteria,4DED4@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_312599_2	710696.Intca_1384	1.156e-104	346.0	COG0204@1|root,COG0204@2|Bacteria,2GKM6@201174|Actinobacteria,4FEZZ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158463_k127_312599_3	405948.SACE_5140	4.305e-31	128.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E1QR@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158463_k127_3137796_1	1386089.N865_19925	4.045e-139	452.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4FF7B@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_3137796_2	235985.BBPN01000020_gene6511	6.33e-91	332.0	COG2267@1|root,COG2267@2|Bacteria,2IBIY@201174|Actinobacteria,2NKIT@228398|Streptacidiphilus	201174|Actinobacteria	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158463_k127_3137796_0	196162.Noca_1059	1.973e-197	623.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4DN9R@85009|Propionibacteriales	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158463_k127_3168767_6	1172188.KB911820_gene2390	2.1e-29	123.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4FGGJ@85021|Intrasporangiaceae	201174|Actinobacteria	S	CHAD	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158463_k127_3168767_3	1172188.KB911820_gene2389	6.191e-112	378.0	COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria,4FH1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158463_k127_3168767_0	1380370.JIBA01000010_gene2364	1.075e-182	577.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FFZ1@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158463_k127_3168767_4	1122611.KB903973_gene2536	7.139e-86	298.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4EMRQ@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158463_k127_3168767_2	1380370.JIBA01000010_gene2366	9.415e-138	449.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4FH2M@85021|Intrasporangiaceae	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158463_k127_3168767_1	1380370.JIBA01000010_gene2367	1.072e-167	533.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4FGG7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Von Willebrand factor A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158463_k127_3168767_5	1172188.KB911820_gene2375	5.244e-66	243.0	COG3214@1|root,COG3214@2|Bacteria,2GP6G@201174|Actinobacteria,4FEJN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158463_k127_3185992_0	1385518.N798_05295	0.0	1075.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4FFG4@85021|Intrasporangiaceae	201174|Actinobacteria	L	ATP-dependent DNA helicase	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158463_k127_3185992_2	1380370.JIBA01000016_gene750	5.673e-48	184.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4FG0U@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158463_k127_3185992_1	1380370.JIBA01000016_gene749	1.135e-126	411.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria,4FFRU@85021|Intrasporangiaceae	201174|Actinobacteria	S	with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF676,PGAP1
SRR25158463_k127_3198443_20	1246474.ANBE01000026_gene1803	1.329e-10	64.0	COG1309@1|root,COG1309@2|Bacteria,2H2H2@201174|Actinobacteria,4EQ44@85012|Streptosporangiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158463_k127_3198443_7	649831.L083_2004	5.278e-104	346.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria,4DE5C@85008|Micromonosporales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158463_k127_3198443_16	1380370.JIBA01000018_gene537	9.23e-46	181.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158463_k127_3198443_18	1122138.AQUZ01000005_gene2507	1.263e-23	104.0	COG1335@1|root,COG1335@2|Bacteria,2IG6Q@201174|Actinobacteria,4DQUF@85009|Propionibacteriales	201174|Actinobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158463_k127_3198443_19	1463917.JODC01000012_gene4517	5.294e-11	68.0	COG1335@1|root,COG1335@2|Bacteria,2IG6Q@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158463_k127_3198443_14	1120949.KB903298_gene5850	4.292e-60	216.0	COG1708@1|root,COG1708@2|Bacteria,2HZ19@201174|Actinobacteria,4DJI9@85008|Micromonosporales	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158463_k127_3198443_9	313589.JNB_14058	3.505e-87	295.0	COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria,4FGIY@85021|Intrasporangiaceae	201174|Actinobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_3198443_17	1306174.JODP01000004_gene956	2.911e-31	128.0	2DNXR@1|root,32ZPP@2|Bacteria,2I2KW@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
SRR25158463_k127_3198443_0	1122138.AQUZ01000080_gene5244	1.636e-178	571.0	COG1653@1|root,COG1653@2|Bacteria,2I3WZ@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158463_k127_3198443_5	1210045.ALNP01000020_gene393	2.943e-125	411.0	COG1175@1|root,COG1175@2|Bacteria,2GNCE@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158463_k127_3198443_6	1394178.AWOO02000015_gene7017	6.141e-112	369.0	COG3833@1|root,COG3833@2|Bacteria,2I4A9@201174|Actinobacteria,4ER8P@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158463_k127_3198443_4	446470.Snas_1407	3.581e-129	434.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EXW8@85014|Glycomycetales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158463_k127_3198443_2	1210045.ALNP01000020_gene396	5.542e-134	440.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria	201174|Actinobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158463_k127_3198443_10	2002.JOEQ01000050_gene8377	1.511e-80	283.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4EG43@85012|Streptosporangiales	2|Bacteria	M	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784,ko:K20534	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Epimerase,Glycos_transf_2
SRR25158463_k127_3198443_15	1172188.KB911820_gene2655	1.55e-53	199.0	COG1846@1|root,COG1846@2|Bacteria,2INPZ@201174|Actinobacteria,4FJY5@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158463_k127_3198443_3	512565.AMIS_14360	5.033e-133	435.0	COG0477@1|root,COG2814@2|Bacteria,2GJPT@201174|Actinobacteria,4DBIM@85008|Micromonosporales	201174|Actinobacteria	EGP	Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158463_k127_3198443_1	1380370.JIBA01000015_gene123	1.018e-168	539.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria,4FFBY@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3198443_13	1385520.N802_07820	3.773e-72	250.0	COG0640@1|root,COG0640@2|Bacteria,2IQKG@201174|Actinobacteria,4FG7S@85021|Intrasporangiaceae	201174|Actinobacteria	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158463_k127_3198443_12	1172188.KB911821_gene1838	9.857e-75	267.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4FGEI@85021|Intrasporangiaceae	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158463_k127_3198443_11	1121017.AUFG01000021_gene2271	6.617e-80	270.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4FFWX@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158463_k127_3198443_8	710696.Intca_2706	2.543e-100	330.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4FECR@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158463_k127_320605_27	448385.sce0136	8.395e-27	124.0	COG3391@1|root,COG3391@2|Bacteria,1Q2JN@1224|Proteobacteria,4386H@68525|delta/epsilon subdivisions,2X9ZH@28221|Deltaproteobacteria,2YVZH@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Stig1
SRR25158463_k127_320605_7	1210045.ALNP01000004_gene3461	6.431e-115	398.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria	201174|Actinobacteria	Q	beta-lactamase domain protein	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
SRR25158463_k127_320605_10	1144312.PMI09_00280	1.895e-94	316.0	COG1028@1|root,COG1028@2|Bacteria,1PE7E@1224|Proteobacteria,2U2VY@28211|Alphaproteobacteria,4B85U@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158463_k127_320605_15	55952.BU52_00060	6.969e-55	196.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_320605_20	469383.Cwoe_0485	2.72e-41	155.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158463_k127_320605_13	1068980.ARVW01000001_gene6908	2.537e-76	264.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4E2KZ@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_320605_16	479431.Namu_0623	4.399e-54	192.0	COG0346@1|root,COG0346@2|Bacteria,2IKNC@201174|Actinobacteria,4EVX8@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_320605_26	926564.KI911644_gene2464	4.458e-28	116.0	2DNW5@1|root,32ZGI@2|Bacteria,2IQ5T@201174|Actinobacteria,4F4WQ@85017|Promicromonosporaceae	201174|Actinobacteria	S	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
SRR25158463_k127_320605_30	1386089.N865_12175	4.555e-07	58.0	2B53J@1|root,31XX1@2|Bacteria,2GZUI@201174|Actinobacteria,4FJPD@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_320605_6	1380393.JHVP01000005_gene3621	1.942e-124	416.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria,4EUTU@85013|Frankiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009405,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0051704	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158463_k127_320605_0	367299.JOEE01000008_gene481	1.405e-251	800.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,2H3NJ@201174|Actinobacteria	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,CheB_methylest,GAF_2,HATPase_c,HisKA,PAS,PAS_4,Response_reg
SRR25158463_k127_320605_19	66875.JODY01000013_gene1045	3.577e-45	171.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
SRR25158463_k127_320605_21	1121946.AUAX01000005_gene5502	3.371e-40	156.0	COG1309@1|root,COG1309@2|Bacteria,2ISE5@201174|Actinobacteria,4DM6H@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_320605_23	298655.KI912266_gene3150	1.179e-37	147.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria,4EU0R@85013|Frankiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_320605_24	1151061.CAJY01000016_gene520	1.096e-34	136.0	COG4994@1|root,COG4994@2|Bacteria,2ISVE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158463_k127_320605_31	1968.JOEV01000002_gene6704	0.0001545	47.0	292W1@1|root,321X5@2|Bacteria,2H63S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_320605_18	1172188.KB911823_gene684	1.02e-52	194.0	COG2203@1|root,COG2203@2|Bacteria,2IRIR@201174|Actinobacteria,4FHGW@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_320605_2	1298863.AUEP01000009_gene154	4.796e-163	517.0	COG0451@1|root,COG0451@2|Bacteria,2IA6C@201174|Actinobacteria,4DQCQ@85009|Propionibacteriales	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158463_k127_320605_4	1246995.AFR_27435	1.081e-136	444.0	COG0584@1|root,COG0584@2|Bacteria,2GM8K@201174|Actinobacteria,4D9WB@85008|Micromonosporales	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158463_k127_320605_9	743718.Isova_2732	1.043e-94	315.0	COG4832@1|root,COG4832@2|Bacteria,2GN4K@201174|Actinobacteria,4F4FK@85017|Promicromonosporaceae	201174|Actinobacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
SRR25158463_k127_320605_1	1193181.BN10_650003	1.443e-203	646.0	COG3266@1|root,COG3266@2|Bacteria,2I302@201174|Actinobacteria,4FHGE@85021|Intrasporangiaceae	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_320605_14	1027371.GOALK_048_00960	1.753e-66	249.0	COG1078@1|root,COG1078@2|Bacteria,2GWU3@201174|Actinobacteria	201174|Actinobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158463_k127_320605_22	1385520.N802_00695	6.865e-39	149.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158463_k127_320605_3	1385520.N802_00700	5.087e-142	478.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	DUF4132,Glyco_transf_4,Glycos_transf_1,HEAT_2,LRV
SRR25158463_k127_320605_11	1121017.AUFG01000010_gene1680	2.024e-77	275.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4FHZQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	ArAE_1
SRR25158463_k127_320605_17	1380370.JIBA01000015_gene326	1.31e-53	192.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria,4FHM1@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158463_k127_320605_29	1298863.AUEP01000004_gene1915	8.714e-13	73.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria,4DVH2@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158463_k127_320605_8	457429.ABJI02000709_gene4288	3.096e-96	318.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria	201174|Actinobacteria	H	reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_320605_12	468556.AQYG01000028_gene427	1.867e-76	262.0	COG5522@1|root,COG5522@2|Bacteria,2I7E9@201174|Actinobacteria	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
SRR25158463_k127_320605_5	1120949.KB903307_gene1398	5.079e-126	408.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_3213757_1	1386089.N865_13865	2.795e-71	260.0	COG1403@1|root,COG1403@2|Bacteria,2GP2N@201174|Actinobacteria,4FGJB@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF222
SRR25158463_k127_3213757_2	2045.KR76_12350	3.014e-69	238.0	COG1917@1|root,COG1917@2|Bacteria,2IIQD@201174|Actinobacteria,4DR5R@85009|Propionibacteriales	201174|Actinobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_3213757_0	1386089.N865_05880	9.147e-140	461.0	COG2508@1|root,COG2508@2|Bacteria,2HNK3@201174|Actinobacteria,4FFFT@85021|Intrasporangiaceae	201174|Actinobacteria	QT	COG2508 Regulator of polyketide synthase expression	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158463_k127_3235860_3	710696.Intca_1649	4.52e-73	248.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4FFXG@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_3235860_1	1385521.N803_08650	2.66e-185	590.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4FG5U@85021|Intrasporangiaceae	201174|Actinobacteria	E	branched-chain amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158463_k127_3235860_4	2074.JNYD01000001_gene6269	1.278e-25	115.0	COG0723@1|root,COG0723@2|Bacteria,2I2JE@201174|Actinobacteria,4E6KK@85010|Pseudonocardiales	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158463_k127_3235860_0	1386089.N865_08255	0.0	1031.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4FF9H@85021|Intrasporangiaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158463_k127_3235860_2	1386089.N865_08250	1.06e-117	385.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4FERR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158463_k127_3236349_1	1386089.N865_09040	5.394e-216	676.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4FECS@85021|Intrasporangiaceae	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158463_k127_3236349_9	1385518.N798_06980	2.858e-75	265.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4FHI9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_3236349_7	1172188.KB911826_gene116	1.831e-96	317.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4FESD@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158463_k127_3236349_5	710696.Intca_0597	2.54e-114	381.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4FFMR@85021|Intrasporangiaceae	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR25158463_k127_3236349_4	1121017.AUFG01000040_gene877	4.342e-132	431.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4FE4C@85021|Intrasporangiaceae	201174|Actinobacteria	S	Coenzyme F420 biosynthesis-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158463_k127_3236349_6	1089455.MOPEL_074_00770	2.868e-103	353.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4F718@85018|Dermatophilaceae	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158463_k127_3236349_8	1385518.N798_13580	5.882e-89	306.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4FFC9@85021|Intrasporangiaceae	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR25158463_k127_3236349_11	1121017.AUFG01000040_gene880	7.367e-55	211.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,4FEDR@85021|Intrasporangiaceae	201174|Actinobacteria	M	NlpC/P60 family	-	-	-	ko:K21471,ko:K21473	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158463_k127_3236349_0	1172188.KB911826_gene132	4.385e-227	713.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4FEA3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Malate dehydrogenase	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158463_k127_3236349_2	526225.Gobs_4733	6.582e-157	509.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4ETU2@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	lpqK	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158463_k127_3236349_3	1298863.AUEP01000001_gene1026	2.314e-155	504.0	COG0019@1|root,COG0019@2|Bacteria,2GRW6@201174|Actinobacteria,4DV2G@85009|Propionibacteriales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_9,Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158463_k127_3236349_12	313589.JNB_02200	6.408e-16	87.0	2DIS5@1|root,30410@2|Bacteria,2GRZ7@201174|Actinobacteria,4FHXD@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3236349_10	1122138.AQUZ01000019_gene8176	1.441e-70	239.0	2DB7W@1|root,2Z7P1@2|Bacteria,2GP9W@201174|Actinobacteria,4DTW1@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158463_k127_3255346_1	1032480.MLP_22430	4.36e-70	241.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4DPK8@85009|Propionibacteriales	201174|Actinobacteria	H	Mg-chelatase subunit ChlI	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
SRR25158463_k127_3255346_0	1120950.KB892709_gene4123	1.86e-264	837.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4DNMK@85009|Propionibacteriales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158463_k127_3255346_3	926550.CLDAP_03400	6.367e-36	154.0	COG1680@1|root,COG1680@2|Bacteria,2G6QM@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158463_k127_3255346_2	700508.D174_02770	1.39e-58	228.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria,234ZC@1762|Mycobacteriaceae	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158463_k127_326108_7	710696.Intca_0836	9.201e-83	278.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4FG47@85021|Intrasporangiaceae	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158463_k127_326108_8	1172188.KB911820_gene2418	5.562e-65	226.0	COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria,4FGN5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_326108_9	266940.Krad_2110	6.659e-24	116.0	COG5401@1|root,COG5401@2|Bacteria	2|Bacteria	T	PFAM Sporulation and spore germination	lpqB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Germane,Gmad1
SRR25158463_k127_326108_2	710696.Intca_1114	7.632e-132	447.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4FFR7@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158463_k127_326108_5	909613.UO65_4945	5.291e-93	319.0	COG0745@1|root,COG0745@2|Bacteria,2GJRR@201174|Actinobacteria,4E18T@85010|Pseudonocardiales	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_326108_10	1211815.CBYP010000036_gene2212	1.758e-17	88.0	COG1366@1|root,COG1366@2|Bacteria,2GX2S@201174|Actinobacteria,4EW6J@85013|Frankiales	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158463_k127_326108_11	710696.Intca_1117	9.638e-09	66.0	2B5FG@1|root,31YA4@2|Bacteria,2H0FM@201174|Actinobacteria,4FI64@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_326108_6	1386089.N865_09380	6.675e-92	309.0	COG1716@1|root,COG1716@2|Bacteria,2GK5I@201174|Actinobacteria,4FG8G@85021|Intrasporangiaceae	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158463_k127_326108_1	1386089.N865_09375	9.925e-179	569.0	COG2304@1|root,COG2304@2|Bacteria,2GMWM@201174|Actinobacteria,4FF26@85021|Intrasporangiaceae	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2,VWA_3
SRR25158463_k127_326108_3	710696.Intca_0544	4.525e-129	425.0	COG0631@1|root,COG0631@2|Bacteria,2GKDM@201174|Actinobacteria,4FFT1@85021|Intrasporangiaceae	201174|Actinobacteria	T	Serine threonine protein phosphatase	prpB10	-	-	-	-	-	-	-	-	-	-	-	DZR,PP2C_2
SRR25158463_k127_326108_0	1386089.N865_09365	3.361e-316	990.0	COG0515@1|root,COG0515@2|Bacteria,2GJ24@201174|Actinobacteria,4FFSZ@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknG	-	2.7.11.1	ko:K14949	ko05152,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	Pkinase,PknG_TPR,PknG_rubred
SRR25158463_k127_326108_4	1122138.AQUZ01000058_gene3503	7.178e-96	327.0	28JK9@1|root,2ZB7T@2|Bacteria,2I80S@201174|Actinobacteria,4DWIZ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3264536_4	1121385.AQXW01000004_gene933	3.829e-54	192.0	COG1028@1|root,COG1028@2|Bacteria,2GJ0E@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_3264536_8	479435.Kfla_0688	7.26e-29	129.0	COG3764@1|root,COG3764@2|Bacteria,2IP7M@201174|Actinobacteria	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158463_k127_3264536_9	1054860.KB913030_gene3185	3.034e-16	93.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158463_k127_3264536_1	1380370.JIBA01000013_gene1571	1.253e-179	567.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4FG9E@85021|Intrasporangiaceae	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	ugpC	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
SRR25158463_k127_3264536_0	1172188.KB911823_gene389	3.172e-213	670.0	COG1653@1|root,COG1653@2|Bacteria,2ICW1@201174|Actinobacteria,4FJUM@85021|Intrasporangiaceae	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8,TAT_signal
SRR25158463_k127_3264536_3	1193181.BN10_10018	5.566e-128	430.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4FF8M@85021|Intrasporangiaceae	201174|Actinobacteria	G	ABC transporter (Permease)	ugpE	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
SRR25158463_k127_3264536_2	367299.JOEE01000005_gene3537	7.698e-155	494.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4FFDG@85021|Intrasporangiaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
SRR25158463_k127_3264536_6	1385519.N801_16020	6.706e-36	144.0	2BU6R@1|root,32PFZ@2|Bacteria,2GU0N@201174|Actinobacteria,4FHWE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3264536_7	1386089.N865_00615	8.632e-34	132.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4FF0W@85021|Intrasporangiaceae	201174|Actinobacteria	J	in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158463_k127_3267535_1	234621.RER_47090	2.071e-133	431.0	COG1131@1|root,COG1131@2|Bacteria,2GJ0Y@201174|Actinobacteria,4FXCQ@85025|Nocardiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_3267535_2	234621.RER_47100	3.078e-110	369.0	COG0842@1|root,COG0842@2|Bacteria,2GK5F@201174|Actinobacteria,4FXFY@85025|Nocardiaceae	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158463_k127_3267535_3	1386089.N865_20405	3.382e-96	328.0	COG4585@1|root,COG4585@2|Bacteria,2GKRM@201174|Actinobacteria,4FFMW@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158463_k127_3267535_4	1150864.MILUP08_45423	4.67e-96	319.0	COG2197@1|root,COG2197@2|Bacteria,2GJ9U@201174|Actinobacteria,4D8N7@85008|Micromonosporales	201174|Actinobacteria	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158463_k127_3267535_6	1172188.KB911821_gene1192	7.111e-72	257.0	COG2267@1|root,COG2267@2|Bacteria,2IAIJ@201174|Actinobacteria,4FEVQ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158463_k127_3267535_0	710696.Intca_2117	2.308e-195	633.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4FFGK@85021|Intrasporangiaceae	201174|Actinobacteria	J	tRNA-dihydrouridine synthase	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
SRR25158463_k127_3267535_5	935866.JAER01000056_gene308	3.922e-90	301.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,4DQGT@85009|Propionibacteriales	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158463_k127_3267535_7	1123251.ATWM01000001_gene556	1.076e-38	150.0	2EP1F@1|root,33GNA@2|Bacteria,2IP6Q@201174|Actinobacteria,4FH5W@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF3806)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3806
SRR25158463_k127_3267535_8	1380354.JIAN01000005_gene1926	2.45e-27	112.0	COG0393@1|root,COG0393@2|Bacteria,2IHTU@201174|Actinobacteria,4F2PF@85016|Cellulomonadaceae	201174|Actinobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158463_k127_3268852_9	1210046.B277_12646	2.847e-77	259.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4FFIE@85021|Intrasporangiaceae	201174|Actinobacteria	E	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158463_k127_3268852_10	367299.JOEE01000004_gene1092	5.658e-77	267.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4FFYA@85021|Intrasporangiaceae	201174|Actinobacteria	E	acetolactate synthase	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158463_k127_3268852_3	1172188.KB911821_gene1492	1.565e-201	640.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4FEUM@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158463_k127_3268852_14	1184607.AUCHE_05_06120	2.08e-46	171.0	COG0586@1|root,COG0586@2|Bacteria,2GSDF@201174|Actinobacteria,4F79Z@85018|Dermatophilaceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158463_k127_3268852_17	479431.Namu_0684	1.033e-20	96.0	2EU3S@1|root,33MKJ@2|Bacteria,2GXJD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3268852_1	1380370.JIBA01000014_gene1979	1.233e-260	811.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4FE7W@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158463_k127_3268852_12	1385521.N803_15815	5.366e-53	203.0	COG2852@1|root,COG2852@2|Bacteria,2IPC8@201174|Actinobacteria,4FH06@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3268852_11	479431.Namu_0818	1.138e-74	258.0	28PN6@1|root,2ZCB1@2|Bacteria,2INN5@201174|Actinobacteria,4EW1M@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158463_k127_3268852_8	479431.Namu_0819	3.421e-85	290.0	COG1309@1|root,COG1309@2|Bacteria,2HTJS@201174|Actinobacteria,4ET9F@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158463_k127_3268852_5	1385520.N802_17990	1.094e-189	598.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4FEDG@85021|Intrasporangiaceae	201174|Actinobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158463_k127_3268852_4	1386089.N865_13980	5.562e-190	599.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4FEYA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158463_k127_3268852_7	1210046.B277_10681	8.394e-94	317.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4FGCS@85021|Intrasporangiaceae	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158463_k127_3268852_2	1385521.N803_16760	2.626e-256	803.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4FFM3@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158463_k127_3268852_13	1385520.N802_16370	6.132e-51	198.0	2BYAG@1|root,2ZC13@2|Bacteria,2IGUZ@201174|Actinobacteria,4FGR3@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3268852_18	1435356.Y013_07805	6.711e-17	96.0	2EG6R@1|root,339YM@2|Bacteria,2I2QW@201174|Actinobacteria,4G9FK@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707
SRR25158463_k127_3268852_16	1283287.KB822583_gene2758	4.36e-37	156.0	COG3153@1|root,COG3153@2|Bacteria,2I4MJ@201174|Actinobacteria,4DVMS@85009|Propionibacteriales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158463_k127_3268852_0	1380356.JNIK01000017_gene2794	0.0	1009.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158463_k127_3268852_6	1385519.N801_19435	1.506e-168	541.0	COG0500@1|root,COG0500@2|Bacteria,2I3GX@201174|Actinobacteria,4FJZ5@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158463_k127_3268852_15	675635.Psed_4912	2.06e-37	144.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2IC7E@201174|Actinobacteria,4EFCC@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158463_k127_3302302_7	1380370.JIBA01000019_gene1025	2.924e-109	356.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4FFUZ@85021|Intrasporangiaceae	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRR25158463_k127_3302302_6	1172188.KB911826_gene18	9.414e-132	423.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4FEFS@85021|Intrasporangiaceae	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158463_k127_3302302_2	1380370.JIBA01000019_gene1027	2.268e-234	731.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4FEWQ@85021|Intrasporangiaceae	201174|Actinobacteria	HQ	Isochorismate synthase	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158463_k127_3302302_0	1380370.JIBA01000019_gene1028	1.756e-268	837.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4FFK6@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158463_k127_3302302_5	1172188.KB911826_gene21	2.023e-136	437.0	COG3246@1|root,COG3246@2|Bacteria,2GMMZ@201174|Actinobacteria,4FIIC@85021|Intrasporangiaceae	201174|Actinobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158463_k127_3302302_4	1380370.JIBA01000019_gene1029	1.35e-147	480.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4FEF4@85021|Intrasporangiaceae	201174|Actinobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
SRR25158463_k127_3302302_9	1380370.JIBA01000019_gene1030	4.086e-11	69.0	2BA2H@1|root,323G9@2|Bacteria,2H84H@201174|Actinobacteria,4FJIQ@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3302302_8	1380370.JIBA01000019_gene1031	3.425e-83	280.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4FGZH@85021|Intrasporangiaceae	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158463_k127_3302302_3	1380370.JIBA01000019_gene1032	2.96e-190	595.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4FE8Y@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158463_k127_3302302_1	1172188.KB911826_gene27	1.688e-248	776.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4FE6Y@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3302302_10	1386089.N865_19925	2.661e-10	73.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4FF7B@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_3308146_4	1385520.N802_00645	4.481e-129	415.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4FERT@85021|Intrasporangiaceae	201174|Actinobacteria	T	Phosphate starvation protein PhoH	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158463_k127_3308146_11	367299.JOEE01000009_gene292	1.484e-41	164.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4FHAI@85021|Intrasporangiaceae	201174|Actinobacteria	FG	Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158463_k127_3308146_10	1380370.JIBA01000014_gene1734	2.464e-43	165.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4FGF5@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_3308146_13	1121017.AUFG01000036_gene647	3.473e-26	122.0	COG5401@1|root,COG5401@2|Bacteria,2IQ3Y@201174|Actinobacteria,4FH7Z@85021|Intrasporangiaceae	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158463_k127_3308146_7	1386089.N865_17080	5.056e-73	253.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4FEBN@85021|Intrasporangiaceae	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158463_k127_3308146_1	1184607.AUCHE_05_04810	1.115e-167	534.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4F6E7@85018|Dermatophilaceae	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158463_k127_3308146_2	1386089.N865_17090	2.662e-146	471.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4FEFK@85021|Intrasporangiaceae	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
SRR25158463_k127_3308146_3	1172188.KB911821_gene1222	4.733e-134	432.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria,4FE9D@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
SRR25158463_k127_3308146_12	1292020.H483_0103620	7.135e-40	153.0	COG3296@1|root,COG3296@2|Bacteria,2IQSV@201174|Actinobacteria	201174|Actinobacteria	J	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158463_k127_3308146_0	1172188.KB911821_gene1225	2.043e-180	593.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4FESQ@85021|Intrasporangiaceae	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158463_k127_3308146_5	1172188.KB911821_gene1228	6.474e-127	420.0	COG0477@1|root,COG2814@2|Bacteria,2GNZJ@201174|Actinobacteria,4FG5N@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3308146_6	1380370.JIBA01000014_gene1746	4.755e-99	330.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4FG0J@85021|Intrasporangiaceae	201174|Actinobacteria	T	protein tyrosine phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
SRR25158463_k127_3308146_9	1151061.CAJY01000031_gene1674	2.845e-53	193.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_3308146_8	477641.MODMU_5545	5.112e-67	237.0	COG4977@1|root,COG4977@2|Bacteria,2I3MB@201174|Actinobacteria,4EXGF@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158463_k127_3308146_14	68260.JOAY01000009_gene550	1.773e-12	67.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158463_k127_3311332_4	1385518.N798_10825	1.233e-115	379.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4FFRP@85021|Intrasporangiaceae	201174|Actinobacteria	I	Diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
SRR25158463_k127_3311332_0	1172188.KB911823_gene548	0.0	1328.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4FE6T@85021|Intrasporangiaceae	201174|Actinobacteria	L	RNA helicase	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158463_k127_3311332_3	369723.Strop_2657	7.561e-124	413.0	COG0654@1|root,COG0654@2|Bacteria,2HEYU@201174|Actinobacteria,4DI72@85008|Micromonosporales	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158463_k127_3311332_7	1298863.AUEP01000006_gene3383	1.419e-52	190.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4DRNX@85009|Propionibacteriales	201174|Actinobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR25158463_k127_3311332_6	367299.JOEE01000002_gene2218	1.218e-80	283.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4FEYN@85021|Intrasporangiaceae	201174|Actinobacteria	P	molybdate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158463_k127_3311332_5	1283283.ATXA01000012_gene4817	5.546e-113	372.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4ESD6@85013|Frankiales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR25158463_k127_3311332_2	1298863.AUEP01000006_gene3380	4.136e-128	423.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,4DPFC@85009|Propionibacteriales	201174|Actinobacteria	P	TOBE domain	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR25158463_k127_3311332_1	1172188.KB911823_gene551	2.743e-130	422.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4FFA5@85021|Intrasporangiaceae	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158463_k127_3316131_10	1160137.KB907308_gene7558	4.432e-39	151.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria,4G0FN@85025|Nocardiaceae	201174|Actinobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158463_k127_3316131_4	1120950.KB892740_gene2540	1.6e-104	360.0	COG2270@1|root,COG2270@2|Bacteria,2GK5A@201174|Actinobacteria,4DQ23@85009|Propionibacteriales	201174|Actinobacteria	S	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3316131_6	1380370.JIBA01000013_gene1483	9.199e-85	283.0	COG1718@1|root,COG1718@2|Bacteria,2GKX1@201174|Actinobacteria,4FEY6@85021|Intrasporangiaceae	201174|Actinobacteria	DT	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3316131_12	1193181.BN10_560082	9.092e-25	105.0	COG1718@1|root,COG1718@2|Bacteria,2GKX1@201174|Actinobacteria,4FEY6@85021|Intrasporangiaceae	201174|Actinobacteria	DT	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3316131_8	1172188.KB911823_gene495	7.395e-40	162.0	2CP0Z@1|root,32SI8@2|Bacteria,2IHXV@201174|Actinobacteria,4FHAW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158463_k127_3316131_0	313589.JNB_15963	2.448e-209	664.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FFZE@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3316131_3	313589.JNB_03180	4.53e-127	424.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4FF53@85021|Intrasporangiaceae	201174|Actinobacteria	J	RRNA methyltransferase	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
SRR25158463_k127_3316131_5	1380370.JIBA01000013_gene1486	2.605e-98	327.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4FE5R@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158463_k127_3316131_1	710696.Intca_1733	1.868e-166	531.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4FFBS@85021|Intrasporangiaceae	201174|Actinobacteria	O	prohibitin homologues	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158463_k127_3316131_9	1386089.N865_07960	2.362e-39	152.0	COG1585@1|root,COG1585@2|Bacteria,2IHZU@201174|Actinobacteria,4FH7Y@85021|Intrasporangiaceae	201174|Actinobacteria	OU	COG1585 Membrane protein implicated in regulation of membrane protease activity	nfeD	-	-	-	-	-	-	-	-	-	-	-	NfeD
SRR25158463_k127_3316131_2	1380370.JIBA01000013_gene1489	3.621e-133	446.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4FFS4@85021|Intrasporangiaceae	201174|Actinobacteria	P	ABC transporter, ATP-binding protein	ylmA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158463_k127_3316131_7	1386089.N865_07970	8.184e-73	253.0	2B34P@1|root,31VSE@2|Bacteria,2HX46@201174|Actinobacteria,4FE3V@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3316131_11	1172188.KB911823_gene484	1.722e-36	138.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4FE4I@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase family 1	glgA	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_332969_6	1043205.AFYF01000065_gene2164	1.791e-18	90.0	COG0088@1|root,COG0088@2|Bacteria,2GRQK@201174|Actinobacteria,4FHXP@85021|Intrasporangiaceae	201174|Actinobacteria	J	repeat protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K16193	-	-	-	-	ko00000	-	-	-	-
SRR25158463_k127_332969_3	1449044.JMLE01000005_gene695	1.034e-108	366.0	COG1835@1|root,COG1835@2|Bacteria,2GS8J@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158463_k127_332969_4	290399.Arth_2683	1.108e-99	336.0	COG0463@1|root,COG0463@2|Bacteria,2GMPV@201174|Actinobacteria,1W8S1@1268|Micrococcaceae	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158463_k127_332969_2	1172188.KB911820_gene2316	3.281e-145	472.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4FFX8@85021|Intrasporangiaceae	201174|Actinobacteria	V	Multidrug transporter MatE	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
SRR25158463_k127_332969_1	313589.JNB_14113	1.166e-161	533.0	COG4995@1|root,COG4995@2|Bacteria,2ICQB@201174|Actinobacteria,4FG53@85021|Intrasporangiaceae	201174|Actinobacteria	E	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CHAT,Peptidase_S8,WD40
SRR25158463_k127_332969_0	313589.JNB_14113	3.198e-185	615.0	COG4995@1|root,COG4995@2|Bacteria,2ICQB@201174|Actinobacteria,4FG53@85021|Intrasporangiaceae	201174|Actinobacteria	E	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CHAT,Peptidase_S8,WD40
SRR25158463_k127_332969_5	313589.JNB_14118	1.769e-18	95.0	COG4995@1|root,COG4995@2|Bacteria,2IG9P@201174|Actinobacteria,4FJAY@85021|Intrasporangiaceae	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
SRR25158463_k127_3337562_5	1172188.KB911827_gene4314	3.01e-158	501.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4FF17@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158463_k127_3337562_4	1449353.JQMQ01000005_gene4715	3.708e-167	550.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,2NFNQ@228398|Streptacidiphilus	201174|Actinobacteria	C	e3 binding domain	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158463_k127_3337562_11	367299.JOEE01000004_gene1411	6.28e-106	353.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4FEWU@85021|Intrasporangiaceae	201174|Actinobacteria	S	epimerase	-	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158463_k127_3337562_19	710696.Intca_2020	1.263e-54	213.0	COG0515@1|root,COG0515@2|Bacteria,2ID99@201174|Actinobacteria,4FGTW@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158463_k127_3337562_6	313589.JNB_14783	2.783e-146	475.0	COG0500@1|root,COG3222@1|root,COG0500@2|Bacteria,COG3222@2|Bacteria,2GN3B@201174|Actinobacteria,4FJNG@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
SRR25158463_k127_3337562_14	1122138.AQUZ01000011_gene4958	9.491e-79	271.0	COG1216@1|root,COG1216@2|Bacteria,2I406@201174|Actinobacteria,4DX0F@85009|Propionibacteriales	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158463_k127_3337562_13	313589.JNB_14773	1.576e-102	338.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4FGFE@85021|Intrasporangiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_3337562_23	391625.PPSIR1_34897	5.778e-18	98.0	COG1807@1|root,COG1807@2|Bacteria,1P31D@1224|Proteobacteria,431BV@68525|delta/epsilon subdivisions,2WWP1@28221|Deltaproteobacteria,2Z0RI@29|Myxococcales	28221|Deltaproteobacteria	M	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3337562_7	313589.JNB_14793	1.026e-131	431.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4FI2F@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158463_k127_3337562_10	313589.JNB_14768	4.099e-108	362.0	COG0642@1|root,COG2205@2|Bacteria,2I3JI@201174|Actinobacteria,4FGKJ@85021|Intrasporangiaceae	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158463_k127_3337562_9	313589.JNB_14763	5.155e-124	410.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4FGXM@85021|Intrasporangiaceae	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	galE3	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158463_k127_3337562_8	1172188.KB911827_gene4310	4.073e-124	409.0	COG0673@1|root,COG0673@2|Bacteria,2GN2Z@201174|Actinobacteria,4FEGC@85021|Intrasporangiaceae	201174|Actinobacteria	S	oxidoreductase	ydgJ	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158463_k127_3337562_18	1120950.KB892720_gene1833	2.619e-59	231.0	COG5479@1|root,COG5479@2|Bacteria,2I6Q0@201174|Actinobacteria,4DX27@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	LGFP,Peptidase_M15_4
SRR25158463_k127_3337562_0	479435.Kfla_1409	7.523e-280	879.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4DNWE@85009|Propionibacteriales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158463_k127_3337562_12	1172188.KB911827_gene4309	1.309e-103	339.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4FFX5@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158463_k127_3337562_22	1137271.AZUM01000008_gene2040	2.006e-36	143.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4ECD7@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158463_k127_3337562_21	426716.JOAJ01000012_gene6681	1.012e-43	172.0	COG1309@1|root,COG1309@2|Bacteria,2I9F9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_3337562_2	367299.JOEE01000004_gene1405	4.433e-192	602.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4FECK@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158463_k127_3337562_15	710696.Intca_2026	5.293e-77	270.0	2DBPK@1|root,2ZA9M@2|Bacteria,2I87Y@201174|Actinobacteria,4FF2W@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4191
SRR25158463_k127_3337562_3	247156.NFA_43750	8.403e-178	567.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4FUZ0@85025|Nocardiaceae	201174|Actinobacteria	P	Integral membrane protein TerC family	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158463_k127_3337562_17	313589.JNB_01220	2.54e-69	241.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4FEGN@85021|Intrasporangiaceae	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158463_k127_3337562_16	85643.Tmz1t_1794	1.136e-69	251.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,2WAT8@28216|Betaproteobacteria,2KYM6@206389|Rhodocyclales	206389|Rhodocyclales	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
SRR25158463_k127_3337562_20	1184607.AUCHE_05_01655	2.154e-44	167.0	COG1714@1|root,COG1714@2|Bacteria,2IQMG@201174|Actinobacteria,4F75Z@85018|Dermatophilaceae	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158463_k127_3337562_1	367299.JOEE01000004_gene1402	8.353e-262	809.0	COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4FEXR@85021|Intrasporangiaceae	201174|Actinobacteria	E	glutamine synthetase	glnA	GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158463_k127_3372454_11	1394178.AWOO02000002_gene1761	4.483e-24	108.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158463_k127_3372454_5	1394178.AWOO02000002_gene1760	2.34e-79	276.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4EHM1@85012|Streptosporangiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158463_k127_3372454_6	1394178.AWOO02000002_gene1759	3.656e-78	285.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4EHZG@85012|Streptosporangiales	201174|Actinobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158463_k127_3372454_3	867903.ThesuDRAFT_02282	5.331e-101	354.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158463_k127_3372454_2	1179773.BN6_08500	4.446e-126	415.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158463_k127_3372454_8	469383.Cwoe_0129	2.95e-72	265.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_3372454_4	479434.Sthe_1954	9.68e-80	284.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27Z82@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_3372454_9	469371.Tbis_1582	2.383e-53	199.0	COG1052@1|root,COG1052@2|Bacteria,2IAIC@201174|Actinobacteria,4EEM3@85010|Pseudonocardiales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158463_k127_3372454_7	215803.DB30_4032	4.537e-73	259.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42N2F@68525|delta/epsilon subdivisions,2X5C2@28221|Deltaproteobacteria,2Z352@29|Myxococcales	28221|Deltaproteobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158463_k127_3372454_10	405948.SACE_2778	2.049e-38	156.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4DYWN@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158463_k127_3372454_1	358823.DF19_00430	3.329e-135	438.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria	201174|Actinobacteria	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158463_k127_3372454_0	1172188.KB911822_gene758	2.322e-141	452.0	COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4FF4R@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the pyridoxine kinase family	pdxY	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
SRR25158463_k127_3375724_4	1298860.AUEM01000012_gene131	2.345e-90	321.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10227	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	SBP_bac_1,SBP_bac_8
SRR25158463_k127_3375724_1	1404245.CGLY_10865	1.354e-194	618.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,22KRJ@1653|Corynebacteriaceae	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158463_k127_3375724_3	246196.MSMEI_1968	1.883e-99	335.0	COG1028@1|root,COG1028@2|Bacteria,2GP5H@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158463_k127_3375724_0	285535.JOEY01000008_gene8868	3.548e-227	713.0	COG0141@1|root,COG0141@2|Bacteria,2GNCN@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	-	-	1.1.1.308	ko:K15509	-	-	-	-	ko00000,ko01000	-	-	-	Histidinol_dh
SRR25158463_k127_3375724_2	285535.JOEY01000008_gene8867	9.194e-106	359.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_3375724_6	1210046.B277_06293	1.304e-53	196.0	COG4339@1|root,COG4339@2|Bacteria,2GMYQ@201174|Actinobacteria,4FHBC@85021|Intrasporangiaceae	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031,HD
SRR25158463_k127_3375724_5	1385521.N803_13055	1.927e-60	212.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4FG8B@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158463_k127_3381640_0	110319.CF8_1371	1.916e-161	534.0	COG2733@1|root,COG2733@2|Bacteria,2GKGM@201174|Actinobacteria,4DNAC@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158463_k127_3381640_4	103733.JNYO01000033_gene7281	2.807e-90	303.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DZNW@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_3381640_1	1283283.ATXA01000026_gene3693	1.646e-136	452.0	COG0642@1|root,COG2205@2|Bacteria,2I53J@201174|Actinobacteria,4EU80@85013|Frankiales	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158463_k127_3381640_5	1386089.N865_11065	1.13e-73	265.0	COG1404@1|root,COG1404@2|Bacteria,2GMN0@201174|Actinobacteria,4FF54@85021|Intrasporangiaceae	201174|Actinobacteria	O	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
SRR25158463_k127_3381640_8	1123320.KB889675_gene3824	2.604e-31	137.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria	201174|Actinobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158463_k127_3381640_2	710696.Intca_1542	1.429e-125	417.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4FEZV@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5- (5- phosphoribosylamino)methylideneamino imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158463_k127_3381640_3	1386089.N865_11055	2.302e-105	345.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4FEAK@85021|Intrasporangiaceae	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158463_k127_3381640_7	1089455.MOPEL_022_00210	6.899e-32	138.0	2C7B6@1|root,31QVE@2|Bacteria,2HT0J@201174|Actinobacteria,4F7Y5@85018|Dermatophilaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3381640_6	1385520.N802_00130	5.154e-72	244.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4FEBG@85021|Intrasporangiaceae	201174|Actinobacteria	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158463_k127_3382726_3	1032480.MLP_15790	9.285e-67	234.0	COG4106@1|root,COG4106@2|Bacteria,2ICXF@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158463_k127_3382726_4	1172188.KB911830_gene3844	4.435e-53	199.0	COG2172@1|root,COG5002@1|root,COG2172@2|Bacteria,COG5002@2|Bacteria,2GPWS@201174|Actinobacteria,4FI1W@85021|Intrasporangiaceae	201174|Actinobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
SRR25158463_k127_3382726_2	479431.Namu_3126	9.133e-132	432.0	COG2267@1|root,COG2267@2|Bacteria,2I47E@201174|Actinobacteria,4EXGS@85013|Frankiales	201174|Actinobacteria	I	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP,Peptidase_S9
SRR25158463_k127_3382726_1	479432.Sros_9017	1.94e-308	955.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4EGNI@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158463_k127_3382726_0	196162.Noca_0662	0.0	1083.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4DNMB@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158463_k127_3383433_11	478801.Ksed_25140	8.204e-09	57.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,1ZVGH@145357|Dermacoccaceae	201174|Actinobacteria	J	Methyltransferase small domain	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
SRR25158463_k127_3383433_2	1032480.MLP_06460	4.091e-250	780.0	COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4DTSJ@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid permease	ansP	-	-	ko:K11738	-	-	-	-	ko00000,ko02000	2.A.3.1.8	-	-	AA_permease
SRR25158463_k127_3383433_7	2045.KR76_16275	4.235e-105	365.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4DPUC@85009|Propionibacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
SRR25158463_k127_3383433_4	1032480.MLP_06480	2.965e-197	634.0	COG2905@1|root,COG2905@2|Bacteria,2HZSI@201174|Actinobacteria,4DTW5@85009|Propionibacteriales	201174|Actinobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	DUF294,DUF294_C
SRR25158463_k127_3383433_6	1172188.KB911822_gene1117	4.255e-162	524.0	COG1222@1|root,COG1222@2|Bacteria,2IA0X@201174|Actinobacteria,4FF4V@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158463_k127_3383433_8	1123024.AUII01000012_gene4221	5.025e-84	294.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E188@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158463_k127_3383433_10	1171373.PACID_05460	5.109e-16	87.0	COG1309@1|root,COG1309@2|Bacteria,2IQGF@201174|Actinobacteria,4DRWJ@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_3383433_1	1385519.N801_01715	3.768e-256	812.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FEEW@85021|Intrasporangiaceae	201174|Actinobacteria	V	Multidrug ABC transporter ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_3383433_0	1172188.KB911826_gene186	7.597e-313	982.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FFHB@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_3383433_5	1454010.JEOE01000011_gene2396	7.605e-180	585.0	COG4425@1|root,COG4425@2|Bacteria,2IBWT@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta-hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158463_k127_3383433_9	1366050.N234_25725	6.902e-25	118.0	COG4225@1|root,COG4225@2|Bacteria,1NQTS@1224|Proteobacteria,2WH9G@28216|Betaproteobacteria,1K5VP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
SRR25158463_k127_3383433_3	31964.CMS1305	7.426e-203	641.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4FK8P@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3414779_17	1385520.N802_08045	9.58e-42	154.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4FGZK@85021|Intrasporangiaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158463_k127_3414779_12	1449353.JQMQ01000005_gene3652	4.375e-69	240.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,2NIPU@228398|Streptacidiphilus	201174|Actinobacteria	J	Ribosomal protein L14p/L23e	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158463_k127_3414779_14	710696.Intca_2745	3.939e-61	212.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4FGY1@85021|Intrasporangiaceae	201174|Actinobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158463_k127_3414779_5	367299.JOEE01000001_gene2186	2.784e-105	343.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4FFBJ@85021|Intrasporangiaceae	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158463_k127_3414779_18	1385518.N798_05965	7.052e-34	130.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4FH9A@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158463_k127_3414779_9	1121385.AQXW01000004_gene2023	4.035e-76	256.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,1ZVXC@145357|Dermacoccaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158463_k127_3414779_8	710696.Intca_2741	1.361e-91	303.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4FGF9@85021|Intrasporangiaceae	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158463_k127_3414779_15	1380370.JIBA01000015_gene151	4.162e-59	206.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4FGRA@85021|Intrasporangiaceae	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158463_k127_3414779_7	367299.JOEE01000001_gene2191	4.618e-101	333.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4FEE0@85021|Intrasporangiaceae	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158463_k127_3414779_21	1385519.N801_05570	1.799e-24	108.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4FHRR@85021|Intrasporangiaceae	201174|Actinobacteria	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158463_k127_3414779_10	1386089.N865_03770	1.615e-75	255.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4FGFZ@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158463_k127_3414779_1	1193181.BN10_760004	1.808e-229	717.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4FE8Q@85021|Intrasporangiaceae	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158463_k127_3414779_11	1386089.N865_03780	4.306e-75	274.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4FGDU@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158463_k127_3414779_3	1386089.N865_03785	8.929e-117	392.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4FEDA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Methionine aminopeptidase	mapA	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158463_k127_3414779_19	1386089.N865_19170	3.082e-30	127.0	COG1848@1|root,COG1848@2|Bacteria,2GPX7@201174|Actinobacteria,4FI13@85021|Intrasporangiaceae	201174|Actinobacteria	S	PIN domain	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158463_k127_3414779_0	298654.FraEuI1c_3602	1.256e-288	937.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EUMV@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
SRR25158463_k127_3414779_13	298654.FraEuI1c_3603	3.769e-67	235.0	COG3945@1|root,COG3945@2|Bacteria,2GQAW@201174|Actinobacteria,4EVTJ@85013|Frankiales	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158463_k127_3414779_6	298655.KI912266_gene3232	5.918e-104	352.0	COG0748@1|root,COG0748@2|Bacteria,2HU2M@201174|Actinobacteria,4EWNH@85013|Frankiales	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3414779_4	1172188.KB911820_gene2353	2.099e-109	364.0	COG1506@1|root,COG1506@2|Bacteria,2HFCE@201174|Actinobacteria,4FFPK@85021|Intrasporangiaceae	201174|Actinobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158463_k127_3414779_16	1122609.AUGT01000005_gene1559	7.061e-57	199.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4DRSK@85009|Propionibacteriales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SRR25158463_k127_3414779_2	1128421.JAGA01000002_gene789	6.128e-223	721.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2NPET@2323|unclassified Bacteria	2|Bacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158463_k127_3414779_20	1121385.AQXW01000004_gene2012	1.472e-29	126.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,1ZW2V@145357|Dermacoccaceae	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158463_k127_341678_10	365528.KB891203_gene3452	2.443e-18	87.0	COG0425@1|root,COG0425@2|Bacteria,2GSF4@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158463_k127_341678_4	1386089.N865_14505	1.023e-91	306.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4FFYP@85021|Intrasporangiaceae	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158463_k127_341678_2	1380370.JIBA01000018_gene396	7.333e-165	523.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria,4FEMQ@85021|Intrasporangiaceae	201174|Actinobacteria	G	Ribokinase	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_341678_6	1122622.ATWJ01000009_gene3222	5.126e-62	214.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4FGV9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158463_k127_341678_3	1385521.N803_06845	1.194e-123	407.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4FF78@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158463_k127_341678_9	935866.JAER01000004_gene3859	1.365e-37	143.0	2E5NA@1|root,330D3@2|Bacteria,2IQ91@201174|Actinobacteria,4DRUP@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRR25158463_k127_341678_1	1386089.N865_14555	1.22e-216	677.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4FEYF@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SRR25158463_k127_341678_5	396014.BF93_03420	7.188e-76	276.0	COG0639@1|root,COG0639@2|Bacteria,2HFPY@201174|Actinobacteria,4FBZC@85020|Dermabacteraceae	201174|Actinobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2
SRR25158463_k127_341678_0	1206743.BAGM01000121_gene1876	0.0	1365.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4FU6V@85025|Nocardiaceae	201174|Actinobacteria	L	ABC transporter	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158463_k127_341678_7	68223.JNZY01000005_gene4014	1.761e-51	184.0	COG3324@1|root,COG3324@2|Bacteria,2IKX6@201174|Actinobacteria	201174|Actinobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_341678_8	1274.HX89_09545	1.158e-45	169.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,1ZWI6@145357|Dermacoccaceae	201174|Actinobacteria	S	Saccharopine dehydrogenase NADP binding domain	LYS1	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030312,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12445	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	Sacchrp_dh_NADP
SRR25158463_k127_3447044_17	1184607.AUCHE_16_01270	6.848e-16	82.0	COG0671@1|root,COG0671@2|Bacteria,2HGG0@201174|Actinobacteria,4F704@85018|Dermatophilaceae	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158463_k127_3447044_16	313589.JNB_10329	8.793e-19	91.0	COG5274@1|root,COG5274@2|Bacteria,2HUTH@201174|Actinobacteria,4FHNW@85021|Intrasporangiaceae	201174|Actinobacteria	CI	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3447044_1	1386089.N865_14955	1.614e-150	490.0	COG1162@1|root,COG1162@2|Bacteria,2GJ37@201174|Actinobacteria,4FEQ3@85021|Intrasporangiaceae	201174|Actinobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158463_k127_3447044_0	1380370.JIBA01000014_gene2151	1.981e-202	647.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4FFKH@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158463_k127_3447044_11	1385520.N802_02585	3.761e-53	193.0	COG2259@1|root,COG2259@2|Bacteria,2HD6Y@201174|Actinobacteria,4FGKG@85021|Intrasporangiaceae	201174|Actinobacteria	S	DoxX family	doxX	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158463_k127_3447044_7	1172186.KB911468_gene1028	1.722e-69	241.0	COG3576@1|root,COG3576@2|Bacteria,2I3RW@201174|Actinobacteria,2396A@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_3447044_2	313589.JNB_07239	6.88e-119	387.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4FF9J@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158463_k127_3447044_10	710696.Intca_2529	4.23e-56	213.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4FH5K@85021|Intrasporangiaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158463_k127_3447044_4	1193181.BN10_1730025	2.512e-105	349.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4FF1Y@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_3447044_15	1380370.JIBA01000014_gene2146	2.294e-25	114.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria,4FHE6@85021|Intrasporangiaceae	201174|Actinobacteria	K	Putative zinc-finger	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158463_k127_3447044_5	1386089.N865_14920	6.295e-101	347.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4FGRR@85021|Intrasporangiaceae	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158463_k127_3447044_6	1386089.N865_14915	1.366e-93	340.0	COG2206@1|root,COG2206@2|Bacteria,2GJB1@201174|Actinobacteria,4FFSG@85021|Intrasporangiaceae	201174|Actinobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158463_k127_3447044_8	2074.JNYD01000047_gene7424	5.122e-66	239.0	COG0778@1|root,COG0778@2|Bacteria,2IEFM@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	1.3.3.13	ko:K21375	-	-	-	-	ko00000,ko01000	-	-	-	Nitroreductase
SRR25158463_k127_3447044_14	1089455.MOPEL_003_01380	9.639e-26	119.0	COG0726@1|root,COG0726@2|Bacteria,2HSXV@201174|Actinobacteria,4F7KW@85018|Dermatophilaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158463_k127_3447044_9	935866.JAER01000014_gene1757	6.259e-62	222.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4DQX0@85009|Propionibacteriales	201174|Actinobacteria	S	Nickel-containing superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158463_k127_3447044_12	1121017.AUFG01000016_gene2594	1.012e-30	136.0	COG2932@1|root,COG2932@2|Bacteria,2I62K@201174|Actinobacteria,4FJZP@85021|Intrasporangiaceae	201174|Actinobacteria	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
SRR25158463_k127_3447044_3	1038858.AXBA01000057_gene4931	7.454e-112	376.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3F1AV@335928|Xanthobacteraceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158463_k127_3453125_5	1386089.N865_16615	4.239e-45	181.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria,4FEME@85021|Intrasporangiaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158463_k127_3453125_4	1386089.N865_16620	1.248e-77	261.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4FEJ8@85021|Intrasporangiaceae	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158463_k127_3453125_3	1386089.N865_16625	7.867e-86	299.0	COG0739@1|root,COG0739@2|Bacteria,2GXEC@201174|Actinobacteria,4FGM1@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidase family M23	pdc2	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158463_k127_3453125_0	1386089.N865_16630	4.878e-123	401.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4FE39@85021|Intrasporangiaceae	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158463_k127_3453125_2	1172188.KB911824_gene3210	2.214e-103	345.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4FF75@85021|Intrasporangiaceae	201174|Actinobacteria	D	Cell division	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158463_k127_3453125_1	1184607.AUCHE_08_02730	1.699e-106	365.0	28Z1N@1|root,2ZKU6@2|Bacteria,2I3ND@201174|Actinobacteria,4F6PZ@85018|Dermatophilaceae	201174|Actinobacteria	-	-	mptB	-	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
SRR25158463_k127_3459227_6	367299.JOEE01000008_gene524	8.31e-83	280.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4FFN3@85021|Intrasporangiaceae	201174|Actinobacteria	M	lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158463_k127_3459227_1	1172188.KB911823_gene632	9.194e-176	560.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4FEF1@85021|Intrasporangiaceae	201174|Actinobacteria	M	GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
SRR25158463_k127_3459227_12	1210046.B277_09557	2.571e-50	187.0	COG1704@1|root,COG1704@2|Bacteria,2GK54@201174|Actinobacteria,4FGDG@85021|Intrasporangiaceae	201174|Actinobacteria	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
SRR25158463_k127_3459227_2	1193181.BN10_590068	1.614e-172	546.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4FF4Y@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158463_k127_3459227_8	345341.KUTG_07818	6.915e-72	246.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4E3B2@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphoesterase	ysnB	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158463_k127_3459227_5	1120950.KB892707_gene4822	1.271e-94	325.0	COG0715@1|root,COG0715@2|Bacteria,2GN9B@201174|Actinobacteria,4DPTI@85009|Propionibacteriales	201174|Actinobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
SRR25158463_k127_3459227_4	1197906.CAJQ02000009_gene3521	3.483e-116	382.0	28IYZ@1|root,2Z8WJ@2|Bacteria,1N1QE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3459227_9	509635.N824_05160	5.008e-71	253.0	COG3214@1|root,COG3214@2|Bacteria,4NGF2@976|Bacteroidetes,1ISPP@117747|Sphingobacteriia	976|Bacteroidetes	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158463_k127_3459227_0	1380370.JIBA01000013_gene1359	1.17e-181	581.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,4FEJK@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158463_k127_3459227_7	1172188.KB911823_gene627	1.719e-80	277.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4FG85@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158463_k127_3459227_3	1386089.N865_15305	5.921e-137	438.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4FEKM@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158463_k127_3459227_10	408672.NBCG_01265	6.288e-71	244.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4DQAA@85009|Propionibacteriales	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158463_k127_3459227_11	1172188.KB911823_gene624	1.628e-70	261.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4FGIB@85021|Intrasporangiaceae	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158463_k127_3473406_24	1172188.KB911826_gene88	1.58e-44	164.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4FFTZ@85021|Intrasporangiaceae	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158463_k127_3473406_8	1246474.ANBE01000038_gene4285	1.258e-115	391.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,4EGT1@85012|Streptosporangiales	201174|Actinobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158463_k127_3473406_22	543632.JOJL01000002_gene8338	4.595e-54	199.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria,4DCWS@85008|Micromonosporales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_3473406_11	1385520.N802_16380	3.076e-85	304.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4FICB@85021|Intrasporangiaceae	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158463_k127_3473406_2	1172188.KB911827_gene4217	9.707e-212	662.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4FHFF@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158463_k127_3473406_5	714083.JH370377_gene2283	1.829e-141	471.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4FKTU@85023|Microbacteriaceae	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158463_k127_3473406_0	263358.VAB18032_18710	0.0	1190.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria,4D8UR@85008|Micromonosporales	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
SRR25158463_k127_3473406_18	208439.AJAP_17480	6.824e-65	228.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,4E3M6@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	furA	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158463_k127_3473406_12	1172188.KB911822_gene913	4.151e-82	280.0	2B3JS@1|root,31W90@2|Bacteria,2GP1G@201174|Actinobacteria,4FGIT@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3473406_4	196162.Noca_0658	1.192e-147	472.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4DPHZ@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158463_k127_3473406_20	1172180.KB911778_gene4707	1.015e-56	199.0	COG0640@1|root,COG0640@2|Bacteria,2IHS2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158463_k127_3473406_13	1463861.JNXE01000008_gene9541	1.79e-80	274.0	COG3832@1|root,COG3832@2|Bacteria,2IFBH@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_3473406_9	463191.SSEG_08360	2.44e-114	379.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_3473406_10	1123023.JIAI01000016_gene3465	1.103e-95	320.0	COG2021@1|root,COG2021@2|Bacteria,2I3EQ@201174|Actinobacteria	201174|Actinobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158463_k127_3473406_23	479431.Namu_0885	7.16e-50	183.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4EVZ1@85013|Frankiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158463_k127_3473406_6	1386089.N865_16170	9.454e-131	435.0	COG2333@1|root,COG2333@2|Bacteria,2GNIE@201174|Actinobacteria,4FIWP@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158463_k127_3473406_16	1385520.N802_12860	8.048e-67	231.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,4FGS5@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158463_k127_3473406_26	1385519.N801_03235	9.555e-15	78.0	2EKHP@1|root,33E7N@2|Bacteria,2GYNB@201174|Actinobacteria,4FI12@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3473406_21	479431.Namu_3007	1.003e-54	195.0	COG4572@1|root,COG4572@2|Bacteria,2IMHQ@201174|Actinobacteria,4ESZC@85013|Frankiales	201174|Actinobacteria	S	ChaB	chaB	-	-	-	-	-	-	-	-	-	-	-	ChaB,Rho_N
SRR25158463_k127_3473406_14	2074.JNYD01000006_gene1626	1.221e-76	273.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4E08C@85010|Pseudonocardiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158463_k127_3473406_1	479431.Namu_5171	1.866e-256	797.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4ERRJ@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158463_k127_3473406_27	1238182.C882_4422	6.521e-07	58.0	COG1846@1|root,COG1846@2|Bacteria,1PD0X@1224|Proteobacteria,2VBMB@28211|Alphaproteobacteria,2JY08@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158463_k127_3473406_7	1380370.JIBA01000013_gene1415	1.939e-124	408.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,4FFDR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
SRR25158463_k127_3473406_19	479431.Namu_5035	2.041e-60	220.0	COG0642@1|root,COG2205@2|Bacteria,2I8QG@201174|Actinobacteria,4EVPC@85013|Frankiales	201174|Actinobacteria	T	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118
SRR25158463_k127_3473406_17	253839.SSNG_03402	6.769e-65	237.0	2AREX@1|root,31GR1@2|Bacteria,2IFPM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3473406_25	452652.KSE_52900	6.442e-25	110.0	COG3553@1|root,COG3553@2|Bacteria,2GSKA@201174|Actinobacteria,2M3N6@2063|Kitasatospora	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2218)	-	-	-	ko:K09956	-	-	-	-	ko00000	-	-	-	DUF2218
SRR25158463_k127_3473406_15	367299.JOEE01000004_gene1082	8.959e-70	246.0	COG2335@1|root,COG2335@2|Bacteria,2IHKV@201174|Actinobacteria,4FGQK@85021|Intrasporangiaceae	201174|Actinobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158463_k127_3473406_3	196162.Noca_4340	2.207e-180	574.0	COG0477@1|root,COG0477@2|Bacteria,COG2814@2|Bacteria,2GIUM@201174|Actinobacteria,4DNWW@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_3475241_10	448385.sce3461	2.127e-15	89.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU5K@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158463_k127_3475241_4	251221.35214697	2.21e-88	316.0	COG0444@1|root,COG0444@2|Bacteria,1G1NU@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158463_k127_3475241_6	1123065.ATWL01000016_gene1980	3.274e-79	284.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158463_k127_3475241_7	1123065.ATWL01000016_gene1979	8.234e-79	274.0	COG0601@1|root,COG0601@2|Bacteria,2GJUS@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158463_k127_3475241_3	1123065.ATWL01000016_gene1978	1.589e-91	323.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158463_k127_3475241_9	1394178.AWOO02000002_gene1754	1.944e-65	235.0	COG1414@1|root,COG1414@2|Bacteria,2GW16@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158463_k127_3475241_8	1123065.ATWL01000016_gene1975	1.24e-76	268.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ligC	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158463_k127_3475241_12	1394178.AWOO02000002_gene1763	4.331e-10	73.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158463_k127_3475241_5	285514.JNWO01000007_gene3969	1.092e-87	306.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158463_k127_3475241_11	414996.IL38_22600	1.82e-10	67.0	COG1141@1|root,COG1141@2|Bacteria,2GQHB@201174|Actinobacteria,40ADT@622450|Actinopolysporales	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
SRR25158463_k127_3475241_2	66874.JOFS01000022_gene5810	1.621e-96	329.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576	1.14.15.11	ko:K17876	-	-	R10158	RC01993	ko00000,ko00199,ko01000	-	-	-	p450
SRR25158463_k127_3475241_0	1123065.ATWL01000016_gene1982	8.676e-125	408.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	lmbE	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158463_k127_3475241_1	1394178.AWOO02000002_gene1755	2.073e-117	388.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4EHY7@85012|Streptosporangiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158463_k127_3499504_0	1122239.AULS01000002_gene817	2.17e-205	644.0	COG4952@1|root,COG4952@2|Bacteria,2GK1Z@201174|Actinobacteria,4FKZD@85023|Microbacteriaceae	201174|Actinobacteria	M	Isomerase	rhaI	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,RhaA
SRR25158463_k127_3499504_1	1132441.KI519455_gene3675	1.591e-143	464.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158463_k127_3499504_2	1132441.KI519455_gene3676	1.788e-10	62.0	COG3618@1|root,COG3618@2|Bacteria	2|Bacteria	H	amidohydrolase	-	-	5.4.3.8	ko:K01845,ko:K07100	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Amidohydro_2,Aminotran_3
SRR25158463_k127_3539615_11	1123024.AUII01000049_gene3643	1.374e-33	143.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_3539615_6	1386089.N865_04370	1.132e-81	278.0	COG1051@1|root,COG1051@2|Bacteria,2I5X3@201174|Actinobacteria,4FEFN@85021|Intrasporangiaceae	201174|Actinobacteria	F	Protein of unknown function (DUF4031)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4031,NUDIX
SRR25158463_k127_3539615_5	1123065.ATWL01000013_gene1151	7.365e-96	323.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ3@201174|Actinobacteria	201174|Actinobacteria	C	PFAM luciferase-like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_3539615_8	1463854.JOHT01000037_gene5469	2.106e-60	227.0	COG0388@1|root,COG0388@2|Bacteria,2GM49@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158463_k127_3539615_0	1298860.AUEM01000012_gene122	2.729e-160	529.0	COG4101@1|root,COG4101@2|Bacteria,2GNUP@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_3539615_1	591158.SSMG_03707	6.126e-151	484.0	COG5485@1|root,COG5485@2|Bacteria,2I95V@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158463_k127_3539615_4	1298860.AUEM01000012_gene124	1.734e-103	347.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_3539615_7	426716.JOAJ01000003_gene3407	3.84e-70	246.0	COG3836@1|root,COG3836@2|Bacteria,2HGEA@201174|Actinobacteria,4FZVX@85025|Nocardiaceae	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158463_k127_3539615_10	1404245.CGLY_10845	1.264e-36	150.0	COG2021@1|root,COG2021@2|Bacteria,2I4CN@201174|Actinobacteria	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158463_k127_3539615_2	1298860.AUEM01000012_gene129	1.941e-121	407.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria,4FM88@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10229	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
SRR25158463_k127_3539615_3	1404245.CGLY_10855	2.098e-111	367.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,22JSG@1653|Corynebacteriaceae	201174|Actinobacteria	P	ABC-type sugar transport systems, permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158463_k127_3539615_9	1298860.AUEM01000012_gene131	1.854e-59	211.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10227	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	SBP_bac_1,SBP_bac_8
SRR25158463_k127_3543882_13	479435.Kfla_2783	5.285e-11	63.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,4DN7Y@85009|Propionibacteriales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	lppS	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158463_k127_3543882_9	1386089.N865_06575	1.34e-103	355.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4FF67@85021|Intrasporangiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158463_k127_3543882_6	1386089.N865_06580	1.456e-131	427.0	COG0620@1|root,COG0620@2|Bacteria,2GMPS@201174|Actinobacteria,4FF5N@85021|Intrasporangiaceae	201174|Actinobacteria	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
SRR25158463_k127_3543882_0	397278.JOJN01000003_gene1817	7.672e-244	765.0	COG3046@1|root,COG3046@2|Bacteria,2GMF6@201174|Actinobacteria,4DPUH@85009|Propionibacteriales	201174|Actinobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	cry1	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
SRR25158463_k127_3543882_14	512565.AMIS_44580	4.119e-10	73.0	COG3507@1|root,COG3507@2|Bacteria,2I5H5@201174|Actinobacteria,4DBJQ@85008|Micromonosporales	201174|Actinobacteria	G	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
SRR25158463_k127_3543882_11	1206732.BAGD01000065_gene2400	2.195e-40	157.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4G260@85025|Nocardiaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158463_k127_3543882_2	1386089.N865_06590	7.671e-191	606.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,4FE6F@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158463_k127_3543882_4	710696.Intca_2390	1.149e-180	572.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4FE7D@85021|Intrasporangiaceae	201174|Actinobacteria	E	COG1104 Cysteine sulfinate desulfinase cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158463_k127_3543882_12	43354.JOIJ01000009_gene2863	9.653e-38	162.0	COG1670@1|root,COG1670@2|Bacteria,2IKXU@201174|Actinobacteria,4E52E@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158463_k127_3543882_10	886293.Sinac_0706	9.339e-91	317.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
SRR25158463_k127_3543882_5	1380370.JIBA01000014_gene2021	6.454e-145	465.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4FE5Q@85021|Intrasporangiaceae	201174|Actinobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158463_k127_3543882_8	1386089.N865_06610	2.764e-129	417.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4FEFQ@85021|Intrasporangiaceae	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158463_k127_3543882_3	471857.Svir_04580	7.553e-188	601.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4DXQ6@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158463_k127_3543882_1	1385518.N798_01790	1.373e-231	726.0	COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,4FF9K@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the mannitol dehydrogenase family	mtlK	-	1.1.1.67	ko:K00045	ko00051,map00051	-	R00868	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
SRR25158463_k127_3543882_7	1385521.N803_12480	5.531e-131	423.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria,4FGC8@85021|Intrasporangiaceae	201174|Actinobacteria	P	Mannitol ABC transporter permease	smoG	-	-	ko:K10229	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	BPD_transp_1
SRR25158463_k127_3553880_15	367299.JOEE01000003_gene2802	6.906e-19	89.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,4FFMG@85021|Intrasporangiaceae	201174|Actinobacteria	G	Maltooligosyl trehalose synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158463_k127_3553880_1	1380370.JIBA01000002_gene2657	1.499e-237	747.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4FEVX@85021|Intrasporangiaceae	201174|Actinobacteria	G	4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase	treZ	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158463_k127_3553880_3	1385520.N802_02170	1.013e-129	452.0	COG3127@1|root,COG3127@2|Bacteria,2I5BW@201174|Actinobacteria,4FII7@85021|Intrasporangiaceae	201174|Actinobacteria	Q	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3553880_6	313589.JNB_06894	6.79e-102	352.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria,4FIG2@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158463_k127_3553880_9	1385518.N798_16480	9.669e-71	247.0	COG1136@1|root,COG1136@2|Bacteria,2IENJ@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	ytrE	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_3553880_5	1172188.KB911822_gene1075	1.155e-113	377.0	COG3153@1|root,COG3153@2|Bacteria,2I3ZT@201174|Actinobacteria,4FGG9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_3553880_12	710696.Intca_2408	7.77e-38	143.0	COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4FHGI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Thiamine-binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
SRR25158463_k127_3553880_8	1120948.KB903246_gene3332	4.26e-77	263.0	COG0644@1|root,COG0644@2|Bacteria,2HRCE@201174|Actinobacteria,4EAHQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158463_k127_3553880_10	1385518.N798_16505	9.675e-64	233.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4FFNF@85021|Intrasporangiaceae	201174|Actinobacteria	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_3553880_0	1184607.AUCHE_02_00330	2.99e-309	955.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4F6MI@85018|Dermatophilaceae	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158463_k127_3553880_14	367299.JOEE01000004_gene1025	2.712e-27	125.0	2AS48@1|root,31HH0@2|Bacteria,2IKT1@201174|Actinobacteria,4FH0Y@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3553880_13	1386089.N865_06675	9.182e-38	162.0	2BITW@1|root,32D1Q@2|Bacteria,2GV9X@201174|Actinobacteria,4FG4D@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3553880_7	710696.Intca_2406	1.342e-99	352.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4FFJ3@85021|Intrasporangiaceae	201174|Actinobacteria	O	Thioredoxin	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158463_k127_3553880_4	298655.KI912266_gene3518	2.768e-114	389.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
SRR25158463_k127_3553880_2	1123065.ATWL01000020_gene3530	6.578e-143	470.0	COG3540@1|root,COG3540@2|Bacteria,2GJCI@201174|Actinobacteria	201174|Actinobacteria	P	alkaline phosphatase	phoD	-	3.1.3.1	ko:K01077,ko:K01113	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	PhoD,PhoD_N
SRR25158463_k127_3553880_11	1386089.N865_06660	1.623e-62	216.0	COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4FFBE@85021|Intrasporangiaceae	201174|Actinobacteria	G	Phosphoglucomutase	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158463_k127_3555008_6	1304865.JAGF01000001_gene1417	5.96e-60	211.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria,4F18U@85016|Cellulomonadaceae	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158463_k127_3555008_4	1172188.KB911822_gene873	5.099e-120	396.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4FE3X@85021|Intrasporangiaceae	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158463_k127_3555008_0	1386089.N865_04920	4.117e-212	677.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4FF2J@85021|Intrasporangiaceae	201174|Actinobacteria	P	Dyp-type peroxidase family	efeN	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
SRR25158463_k127_3555008_1	1386089.N865_04925	7.889e-145	469.0	COG2822@1|root,COG2822@2|Bacteria,2GJPY@201174|Actinobacteria,4FE34@85021|Intrasporangiaceae	201174|Actinobacteria	P	Imelysin	efeO	-	-	ko:K07224	-	-	-	-	ko00000,ko02000	2.A.108.2.3	-	-	Cupredoxin_1,Peptidase_M75
SRR25158463_k127_3555008_10	1172188.KB911822_gene870	1.349e-05	47.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,4FFVR@85021|Intrasporangiaceae	201174|Actinobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR25158463_k127_3555008_3	1386089.N865_04930	7.368e-122	394.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,4FFVR@85021|Intrasporangiaceae	201174|Actinobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR25158463_k127_3555008_2	1386089.N865_04975	2.391e-130	431.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4FG1M@85021|Intrasporangiaceae	201174|Actinobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
SRR25158463_k127_3555008_8	1172188.KB911822_gene860	3.162e-47	184.0	COG1196@1|root,COG1196@2|Bacteria,2IMXX@201174|Actinobacteria,4FHC2@85021|Intrasporangiaceae	201174|Actinobacteria	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158463_k127_3555008_5	1386089.N865_04995	3.475e-99	336.0	COG3012@1|root,COG3012@2|Bacteria,2GJ7F@201174|Actinobacteria,4FFM0@85021|Intrasporangiaceae	201174|Actinobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRR25158463_k127_3555008_7	1380370.JIBA01000011_gene3187	2.12e-56	202.0	COG3920@1|root,COG3920@2|Bacteria,2II0F@201174|Actinobacteria,4FH2G@85021|Intrasporangiaceae	201174|Actinobacteria	T	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158463_k127_3555008_9	1906.SFRA_12910	2.801e-12	68.0	COG0584@1|root,COG0584@2|Bacteria,2GMMS@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158463_k127_3557328_4	1380370.JIBA01000014_gene2004	5.405e-85	284.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4FE8G@85021|Intrasporangiaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158463_k127_3557328_5	1267534.KB906755_gene4121	1.727e-47	183.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158463_k127_3557328_3	686340.Metal_0329	9.616e-92	315.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,1RRUD@1236|Gammaproteobacteria,1XFCW@135618|Methylococcales	135618|Methylococcales	S	Glycosyl transferase	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SRR25158463_k127_3557328_6	234621.RER_47870	9.06e-47	177.0	COG5403@1|root,COG5403@2|Bacteria,2IKKK@201174|Actinobacteria,4G0RZ@85025|Nocardiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
SRR25158463_k127_3557328_0	1385521.N803_16600	1.044e-137	448.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4FE3P@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158463_k127_3557328_2	710696.Intca_2369	5.238e-112	369.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4FEUT@85021|Intrasporangiaceae	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158463_k127_3557328_1	1121385.AQXW01000002_gene129	3.479e-112	366.0	COG0031@1|root,COG0031@2|Bacteria,2GNE4@201174|Actinobacteria	201174|Actinobacteria	E	cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158463_k127_3563658_4	590998.Celf_0122	9.305e-124	404.0	COG2378@1|root,COG2378@2|Bacteria,2GKTS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158463_k127_3563658_6	1122609.AUGT01000023_gene475	3.874e-82	280.0	COG0412@1|root,COG0412@2|Bacteria,2GTZG@201174|Actinobacteria,4DQFU@85009|Propionibacteriales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158463_k127_3563658_2	1116232.AHBF01000116_gene4406	9.154e-147	501.0	COG3616@1|root,COG3616@2|Bacteria,2GJMB@201174|Actinobacteria	201174|Actinobacteria	E	Alanine racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
SRR25158463_k127_3563658_1	1385520.N802_03670	1.501e-158	513.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4FEGM@85021|Intrasporangiaceae	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	gulo	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
SRR25158463_k127_3563658_3	1122138.AQUZ01000101_gene8428	4.594e-126	425.0	COG2271@1|root,COG2271@2|Bacteria,2IEW6@201174|Actinobacteria,4DT82@85009|Propionibacteriales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3563658_7	477641.MODMU_2756	1.926e-65	239.0	COG0673@1|root,COG0673@2|Bacteria,2H7WC@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158463_k127_3563658_0	1112204.GPOL_c02570	8.851e-187	590.0	COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria,4GAW7@85026|Gordoniaceae	201174|Actinobacteria	CH	FAD binding domain	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
SRR25158463_k127_3563658_5	1172188.KB911826_gene88	7.486e-93	310.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4FFTZ@85021|Intrasporangiaceae	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158463_k127_3573085_1	1193181.BN10_270012	6.823e-181	587.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FEVT@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	the major facilitator superfamily	actII-2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3573085_2	1385518.N798_10430	1.334e-127	415.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4FEIM@85021|Intrasporangiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158463_k127_3573085_0	1150399.AQYK01000002_gene3272	3.049e-226	715.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4FMJR@85023|Microbacteriaceae	201174|Actinobacteria	L	DNA ligase N terminus	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158463_k127_3573085_3	1380370.JIBA01000015_gene365	6.629e-83	278.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4FF7H@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158463_k127_3579285_7	1032480.MLP_26400	6.352e-17	91.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4DN53@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
SRR25158463_k127_3579285_8	1132441.KI519454_gene1335	1.258e-13	79.0	COG1846@1|root,COG1846@2|Bacteria,2GSC2@201174|Actinobacteria,1WA9T@1268|Micrococcaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_3579285_5	1050202.KB913024_gene3537	7.969e-30	126.0	COG1846@1|root,COG1846@2|Bacteria,2IQNM@201174|Actinobacteria,40938@622450|Actinopolysporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_3579285_4	743718.Isova_0088	2.35e-63	225.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4F4FX@85017|Promicromonosporaceae	201174|Actinobacteria	S	Macro domain	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158463_k127_3579285_0	710696.Intca_3283	0.0	1326.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4FENT@85021|Intrasporangiaceae	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158463_k127_3579285_1	1122609.AUGT01000003_gene2419	1.539e-192	606.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4DQ5Z@85009|Propionibacteriales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
SRR25158463_k127_3579285_2	479431.Namu_0367	3.981e-163	520.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4EU4Y@85013|Frankiales	201174|Actinobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158463_k127_3579285_3	1385518.N798_06980	1.683e-69	248.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4FHI9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_3579285_6	313589.JNB_15183	1.226e-17	83.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4FEAE@85021|Intrasporangiaceae	201174|Actinobacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158463_k127_3594321_15	1229781.C272_13428	4.341e-09	57.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4FA19@85019|Brevibacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158463_k127_3594321_14	479435.Kfla_1535	3.428e-28	123.0	COG4925@1|root,COG4925@2|Bacteria,2INIQ@201174|Actinobacteria,4DS54@85009|Propionibacteriales	201174|Actinobacteria	S	Cyclophilin-like	-	-	-	-	-	-	-	-	-	-	-	-	Cyclophil_like
SRR25158463_k127_3594321_2	35754.JNYJ01000052_gene6620	1.756e-137	462.0	COG1396@1|root,COG1396@2|Bacteria,2GJS3@201174|Actinobacteria,4DAT2@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158463_k127_3594321_1	266940.Krad_2717	3.281e-171	542.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158463_k127_3594321_5	246197.MXAN_1754	3.945e-118	386.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,42S6B@68525|delta/epsilon subdivisions,2WNKV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158463_k127_3594321_10	1158050.KB895453_gene1012	7.215e-65	229.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria	201174|Actinobacteria	IQ	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_3594321_13	1193181.BN10_230030	3.439e-33	135.0	COG3023@1|root,COG3023@2|Bacteria,2HCX7@201174|Actinobacteria	201174|Actinobacteria	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158463_k127_3594321_8	1184609.KILIM_018_00020	7.213e-100	343.0	COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4F6BI@85018|Dermatophilaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	icaR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_3594321_7	1380370.JIBA01000016_gene886	1.504e-104	346.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4FFAF@85021|Intrasporangiaceae	201174|Actinobacteria	E	Trans-aconitate methyltransferase	tam	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158463_k127_3594321_9	1385518.N798_11795	1.282e-69	239.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4FGMI@85021|Intrasporangiaceae	201174|Actinobacteria	K	MarR family transcriptional regulator	pecS	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_3594321_12	1246995.AFR_28565	5.263e-42	162.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,4DCX9@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_3594321_6	1089455.MOPEL_060_00080	1.322e-108	367.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4F7DD@85018|Dermatophilaceae	201174|Actinobacteria	CG	Glycosyltransferase, MGT family	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
SRR25158463_k127_3594321_0	1386089.N865_09855	1.429e-267	835.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4FEWZ@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yjjK	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158463_k127_3594321_3	1385521.N803_04495	6.711e-124	404.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4FFE8@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158463_k127_3594321_4	1121017.AUFG01000022_gene2168	2.428e-123	407.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4FE9S@85021|Intrasporangiaceae	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158463_k127_3594321_11	1193181.BN10_920003	4.393e-55	198.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4FF9G@85021|Intrasporangiaceae	201174|Actinobacteria	S	G5	rlpA	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
SRR25158463_k127_3628537_6	1172188.KB911825_gene3675	3.387e-120	390.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4FFMT@85021|Intrasporangiaceae	201174|Actinobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
SRR25158463_k127_3628537_12	1385519.N801_00020	4.46e-47	181.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4FGQ5@85021|Intrasporangiaceae	201174|Actinobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158463_k127_3628537_10	710696.Intca_1008	6.173e-68	237.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4FH78@85021|Intrasporangiaceae	201174|Actinobacteria	O	peptidase M22	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158463_k127_3628537_11	367299.JOEE01000007_gene135	5.038e-57	220.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4FGWH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158463_k127_3628537_8	1172188.KB911825_gene3679	5.429e-113	378.0	COG2267@1|root,COG2267@2|Bacteria,2GMCK@201174|Actinobacteria,4FE54@85021|Intrasporangiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158463_k127_3628537_4	1172188.KB911825_gene3680	9.912e-144	466.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4FESS@85021|Intrasporangiaceae	201174|Actinobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158463_k127_3628537_2	1123251.ATWM01000003_gene1252	3.819e-155	507.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4FFIU@85021|Intrasporangiaceae	201174|Actinobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158463_k127_3628537_14	1380370.JIBA01000016_gene802	6.725e-40	170.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,4FHAC@85021|Intrasporangiaceae	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158463_k127_3628537_0	1386089.N865_21600	8.182e-319	991.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4FEZD@85021|Intrasporangiaceae	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158463_k127_3628537_3	1172188.KB911825_gene3684	1.498e-149	483.0	COG1072@1|root,COG1072@2|Bacteria,2GIRR@201174|Actinobacteria,4FEP5@85021|Intrasporangiaceae	201174|Actinobacteria	H	Pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158463_k127_3628537_13	1306174.JODP01000001_gene4781	4.066e-43	169.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria	201174|Actinobacteria	M	G5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5,SLT
SRR25158463_k127_3628537_16	1227261.HMPREF0043_01060	2.044e-10	71.0	COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4D3PH@85005|Actinomycetales	201174|Actinobacteria	S	G5 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5,SLT
SRR25158463_k127_3628537_1	1386089.N865_19735	6.879e-252	782.0	COG1875@1|root,COG1875@2|Bacteria,2GK8U@201174|Actinobacteria,4FEBP@85021|Intrasporangiaceae	201174|Actinobacteria	T	ATP-binding protein	phoH2	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
SRR25158463_k127_3628537_7	1386089.N865_19745	2.452e-119	388.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4FFWU@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS1	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158463_k127_3628537_9	1121385.AQXW01000001_gene776	1.438e-98	342.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,1ZW8F@145357|Dermacoccaceae	201174|Actinobacteria	S	hemolysin III	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158463_k127_3628537_15	1386089.N865_19755	7.721e-12	69.0	2B0SR@1|root,31T53@2|Bacteria,2GRSK@201174|Actinobacteria,4FHXA@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3628537_5	710696.Intca_0994	3.256e-140	452.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4FF2U@85021|Intrasporangiaceae	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158463_k127_3629033_2	110319.CF8_0153	1.094e-38	148.0	COG0789@1|root,COG0789@2|Bacteria,2I571@201174|Actinobacteria,4DSKS@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158463_k127_3629033_0	196162.Noca_1102	0.0	1462.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DPUM@85009|Propionibacteriales	201174|Actinobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158463_k127_3629033_1	350054.Mflv_2413	9.303e-98	321.0	COG0286@1|root,COG0286@2|Bacteria,2GP6Y@201174|Actinobacteria,236I8@1762|Mycobacteriaceae	201174|Actinobacteria	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
SRR25158463_k127_3638485_3	452863.Achl_2419	6.658e-60	216.0	COG2244@1|root,COG2244@2|Bacteria,2I9WN@201174|Actinobacteria	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	-
SRR25158463_k127_3638485_2	595593.JREV01000041_gene280	4.452e-65	232.0	COG1216@1|root,COG1216@2|Bacteria,2IJUB@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K12990	ko02024,ko02025,map02024,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
SRR25158463_k127_3638485_1	1386089.N865_05670	4.304e-91	309.0	COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4FES2@85021|Intrasporangiaceae	201174|Actinobacteria	S	Cytochrome O ubiquinol oxidase	yqjA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
SRR25158463_k127_3638485_0	570268.ANBB01000083_gene2628	2.017e-94	315.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4ENE2@85012|Streptosporangiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SRR25158463_k127_3638485_4	1089544.KB912942_gene462	3.252e-41	154.0	COG2159@1|root,COG2159@2|Bacteria,2GKCJ@201174|Actinobacteria,4DYJI@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158463_k127_3641128_6	67281.JNZZ01000005_gene3321	3.136e-62	216.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,419TH@629295|Streptomyces griseus group	201174|Actinobacteria	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158463_k127_3641128_5	313589.JNB_04990	2.292e-80	270.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4FGE2@85021|Intrasporangiaceae	201174|Actinobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158463_k127_3641128_0	1386089.N865_17055	3.323e-196	620.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4FECW@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	corC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158463_k127_3641128_1	1386089.N865_17050	2.674e-166	531.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4FERB@85021|Intrasporangiaceae	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158463_k127_3641128_3	1121017.AUFG01000036_gene658	4.515e-123	428.0	COG3227@1|root,COG3227@2|Bacteria,2GJEW@201174|Actinobacteria,4FF3Z@85021|Intrasporangiaceae	201174|Actinobacteria	E	peptidase M4	prt1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M4,Peptidase_M4_C
SRR25158463_k127_3641128_2	390989.JOEG01000004_gene3977	6.722e-126	425.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4D930@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158463_k127_3641128_7	1032480.MLP_50680	1.516e-37	150.0	COG4758@1|root,COG4758@2|Bacteria,2GXVR@201174|Actinobacteria,4DSFM@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SRR25158463_k127_3641128_4	710696.Intca_2131	1.036e-87	291.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4FFR9@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158463_k127_367379_6	1298863.AUEP01000011_gene487	1.023e-34	146.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria,4DSB4@85009|Propionibacteriales	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158463_k127_367379_3	710696.Intca_0989	5.819e-143	455.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4FEC2@85021|Intrasporangiaceae	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158463_k127_367379_0	710696.Intca_0990	2.583e-188	610.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4FE6W@85021|Intrasporangiaceae	201174|Actinobacteria	E	cystathionine gamma-synthase	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158463_k127_367379_5	1246474.ANBE01000003_gene2251	2.233e-40	164.0	COG3554@1|root,COG3554@2|Bacteria,2GUNF@201174|Actinobacteria,4EPJ1@85012|Streptosporangiales	201174|Actinobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158463_k127_367379_2	367299.JOEE01000007_gene153	3.837e-147	484.0	COG0145@1|root,COG0145@2|Bacteria,2I2UQ@201174|Actinobacteria,4FJZV@85021|Intrasporangiaceae	201174|Actinobacteria	EQ	MutL protein	-	-	-	-	-	-	-	-	-	-	-	-	MutL
SRR25158463_k127_367379_1	710696.Intca_3196	4.707e-180	572.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4FG1Q@85021|Intrasporangiaceae	201174|Actinobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158463_k127_367379_4	1386089.N865_19770	1.689e-72	247.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4FGFC@85021|Intrasporangiaceae	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158463_k127_367379_8	1385518.N798_06980	2.082e-15	83.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4FHI9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_367379_7	1032480.MLP_46690	5.289e-18	86.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4DR6P@85009|Propionibacteriales	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_3691439_2	479431.Namu_5318	6.853e-139	443.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4ERBS@85013|Frankiales	201174|Actinobacteria	S	peptidase U62, modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158463_k127_3691439_1	981369.JQMJ01000004_gene5125	5.142e-148	483.0	COG0312@1|root,COG0312@2|Bacteria,2GZPS@201174|Actinobacteria,2NHC1@228398|Streptacidiphilus	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158463_k127_3691439_3	526225.Gobs_4733	4.536e-138	452.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4ETU2@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	lpqK	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158463_k127_3691439_4	479431.Namu_2845	2.745e-135	437.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4EUCM@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3691439_0	1172188.KB911820_gene2419	5.097e-150	490.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4FI40@85021|Intrasporangiaceae	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158463_k127_3691439_6	1380370.JIBA01000001_gene2175	3.505e-13	70.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4FEKQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158463_k127_369934_5	1380370.JIBA01000013_gene1491	4.278e-35	135.0	2DQ01@1|root,32UN7@2|Bacteria,2IS50@201174|Actinobacteria,4FGRQ@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_369934_0	367299.JOEE01000004_gene1419	3.709e-134	469.0	COG1752@1|root,COG1752@2|Bacteria,2IAR4@201174|Actinobacteria,4FIT1@85021|Intrasporangiaceae	201174|Actinobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_369934_4	196162.Noca_4536	1.87e-54	207.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4DQMV@85009|Propionibacteriales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158463_k127_369934_3	1380370.JIBA01000010_gene2576	4.433e-95	315.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4FFIW@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158463_k127_369934_1	1380370.JIBA01000010_gene2577	1.448e-106	354.0	COG2335@1|root,COG2335@2|Bacteria,2GJC2@201174|Actinobacteria,4FGIX@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fasciclin	mpt	GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158463_k127_369934_2	1380370.JIBA01000010_gene2578	3.54e-106	345.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4FE2W@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158463_k127_3713157_9	164757.Mjls_0139	8.313e-16	79.0	COG1670@1|root,COG1670@2|Bacteria,2IT84@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158463_k127_3713157_8	1380370.JIBA01000010_gene2499	7.355e-23	109.0	2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4FH9K@85021|Intrasporangiaceae	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
SRR25158463_k127_3713157_6	1386089.N865_16000	7.574e-84	285.0	COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4FFV4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158463_k127_3713157_4	367299.JOEE01000002_gene2612	2.45e-114	372.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4FF6P@85021|Intrasporangiaceae	201174|Actinobacteria	EH	with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158463_k127_3713157_2	1385521.N803_13855	1.889e-160	525.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4FFCB@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158463_k127_3713157_5	710696.Intca_0063	2.062e-100	349.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4FF6D@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158463_k127_3713157_1	1386089.N865_15980	9.27e-174	571.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4FE2U@85021|Intrasporangiaceae	201174|Actinobacteria	M	Cell division protein FtsI	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158463_k127_3713157_0	1172188.KB911820_gene2220	1.547e-200	644.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4FFU6@85021|Intrasporangiaceae	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158463_k127_3713157_3	1122622.ATWJ01000008_gene2987	4.813e-124	413.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4FET4@85021|Intrasporangiaceae	201174|Actinobacteria	T	Serine threonine protein phosphatase	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158463_k127_3713157_7	446466.Cfla_0030	3.623e-48	178.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4F17R@85016|Cellulomonadaceae	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158463_k127_3727976_12	1122609.AUGT01000006_gene1451	1.029e-79	269.0	COG2020@1|root,COG2020@2|Bacteria,2IT1A@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158463_k127_3727976_18	1386089.N865_14150	2.711e-49	185.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4FI5A@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_3727976_20	40571.JOEA01000030_gene5681	4.884e-38	163.0	COG0500@1|root,COG2226@2|Bacteria,2IDNA@201174|Actinobacteria,4E5M5@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158463_k127_3727976_10	40571.JOEA01000030_gene5680	2.13e-99	332.0	COG2207@1|root,COG2207@2|Bacteria,2I3SB@201174|Actinobacteria,4E0KR@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158463_k127_3727976_0	1370125.AUWT01000033_gene1229	4.72e-222	705.0	COG1982@1|root,COG1982@2|Bacteria,2GJ31@201174|Actinobacteria,233VI@1762|Mycobacteriaceae	201174|Actinobacteria	E	Orn Lys Arg decarboxylase, major	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
SRR25158463_k127_3727976_2	35754.JNYJ01000023_gene8238	1.559e-148	487.0	COG0624@1|root,COG0624@2|Bacteria,2I9GD@201174|Actinobacteria,4DCBI@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_3727976_4	926564.KI911624_gene4101	1.139e-126	422.0	COG0657@1|root,COG0657@2|Bacteria,2GJYR@201174|Actinobacteria,4F4XZ@85017|Promicromonosporaceae	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158463_k127_3727976_11	35754.JNYJ01000008_gene3395	1.116e-84	292.0	COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4DCHD@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
SRR25158463_k127_3727976_1	68170.KL590524_gene3534	3.757e-163	530.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DZGD@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_3727976_16	1127134.NOCYR_2239	5.216e-57	204.0	COG3795@1|root,COG3795@2|Bacteria,2IP2I@201174|Actinobacteria,4G1U1@85025|Nocardiaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_3727976_14	1122609.AUGT01000009_gene3364	3.692e-73	251.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria,4DQIA@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_3727976_5	1380370.JIBA01000010_gene2399	5.724e-125	409.0	COG4833@1|root,COG4833@2|Bacteria,2GNQY@201174|Actinobacteria,4FIKV@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 76	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_76
SRR25158463_k127_3727976_9	298655.KI912266_gene4026	2.615e-103	343.0	COG3386@1|root,COG3386@2|Bacteria,2HE8D@201174|Actinobacteria	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
SRR25158463_k127_3727976_24	1323361.JPOC01000065_gene9	7.685e-11	65.0	2DRF3@1|root,33BFR@2|Bacteria,2IQ54@201174|Actinobacteria,4G2YR@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3727976_6	1122609.AUGT01000010_gene3640	2.877e-123	420.0	COG2207@1|root,COG2207@2|Bacteria,2GP19@201174|Actinobacteria,4DPTP@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158463_k127_3727976_3	298655.KI912266_gene2249	1.772e-127	443.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4EXE3@85013|Frankiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158463_k127_3727976_26	349521.HCH_03229	5.243e-05	57.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,UnbV_ASPIC,VCBS
SRR25158463_k127_3727976_7	1123024.AUII01000015_gene3750	1.668e-104	361.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DXC9@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
SRR25158463_k127_3727976_21	749927.AMED_6508	8.378e-32	138.0	2C2I0@1|root,31SYT@2|Bacteria,2H0RS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3727976_8	562973.HMPREF0059_00662	3.736e-104	357.0	COG1171@1|root,COG1171@2|Bacteria,2I8UC@201174|Actinobacteria,4D46J@85005|Actinomycetales	201174|Actinobacteria	E	Psort location Cytoplasmic, score 7.50	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158463_k127_3727976_13	1452535.JARD01000026_gene457	4.383e-79	268.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4FPWK@85023|Microbacteriaceae	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158463_k127_3727976_23	1171373.PACID_15150	1.453e-20	94.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158463_k127_3727976_25	367299.JOEE01000011_gene3162	9.546e-09	57.0	COG4430@1|root,COG4430@2|Bacteria,2HY1A@201174|Actinobacteria,4FJA4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3727976_17	1120960.ATXG01000004_gene1691	5.535e-53	190.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria,4FPT5@85023|Microbacteriaceae	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158463_k127_3727976_19	35754.JNYJ01000006_gene5186	1.026e-42	168.0	COG0617@1|root,COG0617@2|Bacteria,2IFKR@201174|Actinobacteria,4DKS0@85008|Micromonosporales	201174|Actinobacteria	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit
SRR25158463_k127_3727976_15	1385518.N798_06980	5.442e-59	216.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4FHI9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_3727976_22	1463934.JOCF01000089_gene2154	1.558e-29	122.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158463_k127_37416_2	1172188.KB911821_gene2075	3.709e-90	302.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,4FK2A@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158463_k127_37416_1	1385519.N801_15185	3.139e-155	508.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,2GNPX@201174|Actinobacteria,4FFVN@85021|Intrasporangiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	osaB	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158463_k127_37416_3	1385519.N801_15190	2.037e-40	168.0	COG0745@1|root,COG0745@2|Bacteria,2IS52@201174|Actinobacteria,4FH4M@85021|Intrasporangiaceae	201174|Actinobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158463_k127_37416_0	1380370.JIBA01000015_gene376	7.124e-313	980.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158463_k127_3741668_1	1185876.BN8_01035	1.102e-58	214.0	COG4292@1|root,COG4292@2|Bacteria,4NVSI@976|Bacteroidetes,47TAV@768503|Cytophagia	976|Bacteroidetes	S	Bacterial low temperature requirement A protein (LtrA)	ltrA	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158463_k127_3741668_0	290399.Arth_3233	2.604e-214	710.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	-
SRR25158463_k127_3741668_2	1380370.JIBA01000013_gene1263	6.768e-56	213.0	2A3EE@1|root,30RX0@2|Bacteria,2IBKW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3743224_11	1123322.KB904680_gene3274	3.571e-16	81.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria	201174|Actinobacteria	J	elongation factor G	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158463_k127_3743224_5	1068978.AMETH_1487	1.262e-97	329.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4DY3P@85010|Pseudonocardiales	201174|Actinobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158463_k127_3743224_0	1121017.AUFG01000003_gene3403	1.875e-228	721.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria,4FEG1@85021|Intrasporangiaceae	201174|Actinobacteria	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158463_k127_3743224_10	1894.JOER01000010_gene2217	2.652e-44	171.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria	201174|Actinobacteria	S	beta-lactamase domain protein	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158463_k127_3743224_9	469371.Tbis_1257	3.443e-50	200.0	COG0640@1|root,COG0640@2|Bacteria,2GPH2@201174|Actinobacteria,4E37F@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158463_k127_3743224_7	1123258.AQXZ01000013_gene1938	2.391e-58	205.0	COG0824@1|root,COG0824@2|Bacteria,2IJV6@201174|Actinobacteria,4G0ED@85025|Nocardiaceae	201174|Actinobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158463_k127_3743224_4	1123258.AQXZ01000013_gene1939	1.035e-162	532.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4FTYR@85025|Nocardiaceae	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158463_k127_3743224_3	1298863.AUEP01000007_gene351	5.701e-173	552.0	COG1226@1|root,COG1226@2|Bacteria,2HZRR@201174|Actinobacteria,4DTS4@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_N
SRR25158463_k127_3743224_2	313589.JNB_12199	8.55e-193	608.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4FE3R@85021|Intrasporangiaceae	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158463_k127_3743224_8	1032480.MLP_20730	1.37e-53	192.0	COG0346@1|root,COG0346@2|Bacteria,2I9G1@201174|Actinobacteria,4DRTR@85009|Propionibacteriales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3743224_6	1449068.JMLQ01000004_gene1054	7.204e-89	301.0	COG0596@1|root,COG0596@2|Bacteria,2HHMN@201174|Actinobacteria,4FZ71@85025|Nocardiaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158463_k127_3743224_1	67257.JODR01000030_gene2432	1.071e-213	672.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158463_k127_3757174_2	1385519.N801_14250	5.476e-65	224.0	COG1045@1|root,COG1045@2|Bacteria,2IHW5@201174|Actinobacteria,4FGJA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Serine acetyltransferase	cysE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SRR25158463_k127_3757174_0	1283283.ATXA01000011_gene4745	2.206e-126	436.0	COG4995@1|root,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4EUJU@85013|Frankiales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158463_k127_3757174_6	479431.Namu_2966	4.658e-28	126.0	2E27K@1|root,32XDT@2|Bacteria,2GRMM@201174|Actinobacteria,4EWHU@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3757174_3	1172188.KB911822_gene864	1.606e-59	212.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4FGYD@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158463_k127_3757174_1	1283283.ATXA01000011_gene4744	1.137e-97	352.0	COG1404@1|root,COG1404@2|Bacteria,2GNIX@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158463_k127_3757174_4	469371.Tbis_0111	3.748e-57	211.0	COG2207@1|root,COG2207@2|Bacteria,2GWDZ@201174|Actinobacteria,4E57H@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158463_k127_3757174_5	1035308.AQYY01000001_gene2561	1.896e-37	155.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_3775415_3	1298863.AUEP01000005_gene2393	1.923e-47	171.0	2BK9Y@1|root,32EQ4@2|Bacteria,2GMZH@201174|Actinobacteria,4DR19@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3775415_0	1298863.AUEP01000005_gene2394	6.175e-233	724.0	COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4DN8I@85009|Propionibacteriales	201174|Actinobacteria	E	phosphoserine phosphatase	serB	GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iNJ661.Rv3042c	ACT_6,HAD
SRR25158463_k127_3775415_2	1298863.AUEP01000005_gene2395	1.5e-73	252.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4DRZU@85009|Propionibacteriales	201174|Actinobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158463_k127_3775415_1	1298863.AUEP01000005_gene2396	1.963e-169	536.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,4DP1Z@85009|Propionibacteriales	201174|Actinobacteria	PQ	Peptidase family S51	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158463_k127_3775415_4	1298863.AUEP01000005_gene2397	5.041e-44	162.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,4DP39@85009|Propionibacteriales	201174|Actinobacteria	HJM	RimK-like ATP-grasp domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158463_k127_379099_9	743718.Isova_2287	2.063e-135	438.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4F3G9@85017|Promicromonosporaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 1	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158463_k127_379099_17	390989.JOEG01000019_gene5909	1.269e-76	261.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria,4DE9F@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_379099_18	926564.KI911686_gene5549	1.075e-74	263.0	COG0524@1|root,COG0524@2|Bacteria,2GQ7J@201174|Actinobacteria,4F4JB@85017|Promicromonosporaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.187	ko:K19978	ko00525,ko01130,map00525,map01130	-	R11184	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158463_k127_379099_20	344747.PM8797T_13620	3.924e-57	209.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158463_k127_379099_13	35754.JNYJ01000006_gene5204	1.762e-110	364.0	COG0454@1|root,COG0456@2|Bacteria,2I8Y1@201174|Actinobacteria,4DDXD@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_379099_14	1380390.JIAT01000009_gene1638	2.852e-101	340.0	COG0491@1|root,COG0491@2|Bacteria,2I9IC@201174|Actinobacteria,4CRBU@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158463_k127_379099_0	1172188.KB911822_gene1022	8.814e-287	889.0	COG1012@1|root,COG1012@2|Bacteria,2GNJJ@201174|Actinobacteria,4FES3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158463_k127_379099_1	101510.RHA1_ro07101	1.626e-220	699.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4FV6S@85025|Nocardiaceae	201174|Actinobacteria	EGP	transporter	kgtP	-	-	ko:K03761	-	-	-	-	ko00000,ko02000	2.A.1.6.2	-	-	MFS_1,Sugar_tr
SRR25158463_k127_379099_11	931627.MycrhDRAFT_6701	6.396e-125	424.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,233R3@1762|Mycobacteriaceae	201174|Actinobacteria	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158463_k127_379099_6	1386089.N865_19410	9.06e-158	506.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria,4FF7A@85021|Intrasporangiaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158463_k127_379099_21	1122622.ATWJ01000008_gene2846	1.413e-50	188.0	COG2050@1|root,COG2050@2|Bacteria,2IKWI@201174|Actinobacteria,4FGZ9@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Thioesterase superfamily	paaD	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SRR25158463_k127_379099_19	1211815.CBYP010000046_gene844	1.582e-58	211.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria	201174|Actinobacteria	L	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158463_k127_379099_16	1206743.BAGM01000130_gene913	2.359e-78	271.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4FV6H@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158463_k127_379099_10	1386089.N865_00025	3.845e-134	446.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4FE5G@85021|Intrasporangiaceae	201174|Actinobacteria	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028,ko:K17076	ko02010,map02010	M00236,M00589	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.20	-	-	ABC_tran
SRR25158463_k127_379099_15	1463821.JOGR01000004_gene2321	2.638e-96	323.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4EZD1@85014|Glycomycetales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158463_k127_379099_12	1386089.N865_00035	1.73e-122	399.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4FGHJ@85021|Intrasporangiaceae	201174|Actinobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158463_k127_379099_3	1380370.JIBA01000011_gene3289	3.202e-210	665.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,4FG54@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158463_k127_379099_2	1172188.KB911822_gene1009	1.865e-220	692.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4FFIS@85021|Intrasporangiaceae	201174|Actinobacteria	C	cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158463_k127_379099_8	1032480.MLP_24660	5.445e-142	457.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4DN35@85009|Propionibacteriales	201174|Actinobacteria	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158463_k127_379099_4	1210046.B277_02129	1.176e-162	541.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4FFQC@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_379099_7	1210046.B277_02124	2.24e-148	509.0	COG4987@1|root,COG4987@2|Bacteria,2H79B@201174|Actinobacteria,4FF8E@85021|Intrasporangiaceae	201174|Actinobacteria	CO	ABC transporter, ATP-binding protein	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158463_k127_379099_22	710696.Intca_3566	1.21e-07	62.0	2BK7Q@1|root,32EMK@2|Bacteria,2GXAI@201174|Actinobacteria,4FHZP@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_379099_5	926564.KI911642_gene2409	8.9e-162	516.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4F3RP@85017|Promicromonosporaceae	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158463_k127_379099_23	710696.Intca_0212	0.0002117	51.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4FGSB@85021|Intrasporangiaceae	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158463_k127_3796207_6	1122622.ATWJ01000011_gene2329	8.082e-44	169.0	COG0662@1|root,COG0662@2|Bacteria,2IHU8@201174|Actinobacteria,4FJ2W@85021|Intrasporangiaceae	201174|Actinobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158463_k127_3796207_4	1122611.KB904029_gene5322	1.558e-49	183.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4EJAH@85012|Streptosporangiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_3796207_1	1386089.N865_17840	3.818e-286	893.0	COG0339@1|root,COG0339@2|Bacteria,2GM2Z@201174|Actinobacteria,4FFRS@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptidase family M3	-	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158463_k127_3796207_2	1386089.N865_17835	6.452e-193	623.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4FEY7@85021|Intrasporangiaceae	201174|Actinobacteria	I	Lipopolysaccharide modification acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158463_k127_3796207_3	316274.Haur_1430	1.269e-105	390.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158463_k127_3796207_5	414684.RC1_2214	4.807e-47	197.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,2JR7Z@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic oligopeptide-binding protein	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158463_k127_3796207_8	1123251.ATWM01000012_gene2756	3.707e-27	113.0	COG1254@1|root,COG1254@2|Bacteria,2IQ4M@201174|Actinobacteria,4FHHA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158463_k127_3796207_7	1380370.JIBA01000014_gene1918	1.44e-40	153.0	COG1605@1|root,COG1605@2|Bacteria,2IQ46@201174|Actinobacteria,4FH4E@85021|Intrasporangiaceae	201174|Actinobacteria	E	chorismate mutase	tyrA	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
SRR25158463_k127_3796207_0	710696.Intca_2301	0.0	1468.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4FFAB@85021|Intrasporangiaceae	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158463_k127_3796207_10	1385521.N803_17015	1.912e-07	55.0	29YYC@1|root,30KV6@2|Bacteria,2GYTF@201174|Actinobacteria,4FHZC@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3796207_9	710696.Intca_2300	1.14e-12	74.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4FF05@85021|Intrasporangiaceae	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158463_k127_3802393_6	1079986.JH164861_gene7150	5.021e-40	160.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158463_k127_3802393_7	58344.JOEL01000044_gene886	6.55e-07	53.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
SRR25158463_k127_3802393_3	557599.MKAN_11005	7.157e-95	332.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,236Z5@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K06609	-	-	-	-	ko00000,ko02000	2.A.1.1.26	-	-	Sugar_tr
SRR25158463_k127_3802393_0	1184607.AUCHE_05_03960	4.842e-259	817.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4F6GP@85018|Dermatophilaceae	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158463_k127_3802393_4	367299.JOEE01000008_gene554	4.485e-85	287.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4FGBN@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
SRR25158463_k127_3802393_1	1172188.KB911823_gene605	8.748e-144	470.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4FF8J@85021|Intrasporangiaceae	201174|Actinobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158463_k127_3802393_2	710696.Intca_1837	1.016e-134	443.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4FEXM@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158463_k127_3802393_5	1157635.KB892079_gene6523	5.75e-62	217.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158463_k127_3830297_1	561175.KB894096_gene863	2.423e-87	291.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4EH81@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoglycerate kinase	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158463_k127_3830297_0	1210045.ALNP01000010_gene1150	4.082e-117	385.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158463_k127_3830297_4	1298863.AUEP01000005_gene2451	5.948e-30	119.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4DS3V@85009|Propionibacteriales	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158463_k127_3830297_2	566461.SSFG_05421	4.55e-56	203.0	2CNY9@1|root,31GEE@2|Bacteria,2IKKZ@201174|Actinobacteria	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	-	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158463_k127_3830297_3	1380393.JHVP01000020_gene237	3.554e-39	149.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4ERV0@85013|Frankiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158463_k127_3844091_1	1172188.KB911821_gene1951	6.854e-164	526.0	COG2850@1|root,COG2850@2|Bacteria,2GMR2@201174|Actinobacteria,4FF39@85021|Intrasporangiaceae	201174|Actinobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158463_k127_3844091_4	543632.JOJL01000004_gene3890	2.67e-14	77.0	2C2Y4@1|root,333DJ@2|Bacteria,2GT36@201174|Actinobacteria,4DES7@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3844091_2	1386089.N865_04770	7.921e-159	504.0	COG0491@1|root,COG0491@2|Bacteria,2HP5U@201174|Actinobacteria,4FFMQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158463_k127_3844091_3	1172188.KB911821_gene1948	3.157e-119	393.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4FEWK@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3844091_0	1172188.KB911821_gene1947	1.571e-180	578.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4FFYK@85021|Intrasporangiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158463_k127_3844091_5	1386089.N865_03480	1.373e-13	74.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4FHNB@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158463_k127_3847787_0	1386089.N865_16370	1.835e-180	575.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4FET1@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC1,APH
SRR25158463_k127_3847787_2	1172188.KB911831_gene3980	1.77e-80	273.0	COG1309@1|root,COG1309@2|Bacteria,2IKPS@201174|Actinobacteria,4FI03@85021|Intrasporangiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_3847787_5	1172188.KB911831_gene3979	8.775e-45	172.0	COG4319@1|root,COG4319@2|Bacteria,2GUR1@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158463_k127_3847787_7	1172188.KB911821_gene1699	6.425e-23	111.0	COG0476@1|root,COG0476@2|Bacteria,2HXET@201174|Actinobacteria,4FGE8@85021|Intrasporangiaceae	201174|Actinobacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3847787_6	710696.Intca_2546	9.071e-24	101.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria,4FHV1@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3847787_3	1123320.KB889672_gene3692	1.122e-70	245.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158463_k127_3847787_4	367299.JOEE01000014_gene927	1.073e-69	240.0	COG0494@1|root,COG0494@2|Bacteria,2GU6D@201174|Actinobacteria,4FGQU@85021|Intrasporangiaceae	201174|Actinobacteria	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158463_k127_3847787_1	1385518.N798_08875	2.815e-135	451.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4FFHM@85021|Intrasporangiaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158463_k127_3868285_6	1380370.JIBA01000012_gene3463	2.023e-71	248.0	COG1443@1|root,COG1443@2|Bacteria,2GM26@201174|Actinobacteria,4FGCD@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0071704,GO:0090407,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1745c	NUDIX
SRR25158463_k127_3868285_7	1172188.KB911821_gene1765	7.302e-65	230.0	arCOG10154@1|root,3068I@2|Bacteria,2IKV1@201174|Actinobacteria,4FH7P@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3868285_2	367299.JOEE01000010_gene3337	8.404e-107	355.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4FFKW@85021|Intrasporangiaceae	201174|Actinobacteria	S	NIF3 (NGG1p interacting factor 3)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158463_k127_3868285_5	1385518.N798_02695	2.079e-83	284.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4FFIN@85021|Intrasporangiaceae	201174|Actinobacteria	S	C4-type zinc ribbon domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158463_k127_3868285_1	1210046.B277_11310	1.676e-111	390.0	COG0328@1|root,COG0328@2|Bacteria,2I4IN@201174|Actinobacteria,4FF0E@85021|Intrasporangiaceae	201174|Actinobacteria	L	Reverse transcriptase-like	-	-	3.1.26.4,3.1.3.73	ko:K03469,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Glyoxalase_4,His_Phos_1,RVT_3
SRR25158463_k127_3868285_0	1385518.N798_02685	4.653e-205	643.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4FEG7@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0391	Cys_Met_Meta_PP
SRR25158463_k127_3868285_4	1386089.N865_07740	4.661e-87	308.0	COG3022@1|root,COG3022@2|Bacteria,2GJPM@201174|Actinobacteria,4FFCQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the UPF0246 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
SRR25158463_k127_3868285_3	313589.JNB_15268	1.734e-106	353.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4FFDU@85021|Intrasporangiaceae	201174|Actinobacteria	P	Arsenical pump membrane protein	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
SRR25158463_k127_387093_5	1172188.KB911821_gene1501	1.555e-71	246.0	COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4FFZK@85021|Intrasporangiaceae	201174|Actinobacteria	T	Phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158463_k127_387093_4	1172188.KB911821_gene2079	9.73e-106	349.0	COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4FHSY@85021|Intrasporangiaceae	201174|Actinobacteria	G	Major intrinsic protein	aqpZ	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
SRR25158463_k127_387093_0	1385518.N798_17250	0.0	1002.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4FESM@85021|Intrasporangiaceae	201174|Actinobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158463_k127_387093_3	1380370.JIBA01000014_gene1985	2.48e-108	358.0	COG0454@1|root,COG0456@2|Bacteria,2I9GA@201174|Actinobacteria,4FG69@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_387093_2	1385518.N798_01730	1.849e-169	535.0	COG0208@1|root,COG0208@2|Bacteria,2GKGZ@201174|Actinobacteria,4FEC5@85021|Intrasporangiaceae	201174|Actinobacteria	F	acyl-ACP desaturase	desA	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
SRR25158463_k127_387093_1	1172188.KB911821_gene1494	5.839e-259	807.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4FFIE@85021|Intrasporangiaceae	201174|Actinobacteria	E	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158463_k127_3871967_13	1380370.JIBA01000013_gene1270	1.296e-105	366.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4FG9N@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158463_k127_3871967_15	1032480.MLP_05370	2.65e-82	288.0	COG0122@1|root,COG0122@2|Bacteria,2IB0Q@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158463_k127_3871967_11	1202768.JROF01000001_gene1745	3.095e-107	359.0	COG1893@1|root,arCOG04139@2157|Archaea,2XW0P@28890|Euryarchaeota,23S7V@183963|Halobacteria	183963|Halobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158463_k127_3871967_21	1449346.JQMO01000003_gene2682	7.948e-54	192.0	2B1QU@1|root,31S8F@2|Bacteria,2II5X@201174|Actinobacteria,2M37J@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
SRR25158463_k127_3871967_29	1121272.KB903250_gene2722	7.32e-21	101.0	2E4RI@1|root,32ZK2@2|Bacteria,2HWWC@201174|Actinobacteria,4DKJ2@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3871967_1	1380370.JIBA01000018_gene542	1.322e-170	569.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4FGDV@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158463_k127_3871967_14	477641.MODMU_1839	5.086e-89	300.0	2C3WA@1|root,2Z8P1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3871967_7	1122164.JHWF01000008_gene1306	6.478e-131	429.0	COG0654@1|root,COG0654@2|Bacteria,1R7KI@1224|Proteobacteria,1S5AW@1236|Gammaproteobacteria,1JDQK@118969|Legionellales	118969|Legionellales	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158463_k127_3871967_24	298655.KI912266_gene3832	4.859e-39	152.0	COG3476@1|root,COG3476@2|Bacteria	2|Bacteria	T	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	tspO	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	NAD_binding_10,TspO_MBR
SRR25158463_k127_3871967_2	935866.JAER01000014_gene1812	7.452e-161	533.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,4DNC6@85009|Propionibacteriales	201174|Actinobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158463_k127_3871967_22	1110697.NCAST_08_00720	2.089e-52	211.0	COG1266@1|root,COG1266@2|Bacteria,2I925@201174|Actinobacteria,4FYDE@85025|Nocardiaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158463_k127_3871967_8	477641.MODMU_5290	2.426e-127	438.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4ESJH@85013|Frankiales	201174|Actinobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA,TspO_MBR
SRR25158463_k127_3871967_18	543632.JOJL01000035_gene5070	4.941e-75	263.0	COG5012@1|root,COG5012@2|Bacteria,2I2EI@201174|Actinobacteria	201174|Actinobacteria	S	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SRR25158463_k127_3871967_28	1077972.ARGLB_047_00950	2.698e-22	109.0	2E5RJ@1|root,330G5@2|Bacteria,2GQFX@201174|Actinobacteria,1WA4E@1268|Micrococcaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4232
SRR25158463_k127_3871967_20	367299.JOEE01000002_gene2629	3.813e-61	214.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158463_k127_3871967_17	367299.JOEE01000002_gene2630	9.491e-79	271.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria,4FEI9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_3871967_23	1380356.JNIK01000019_gene344	1.482e-43	166.0	COG3607@1|root,COG3607@2|Bacteria,2IKVS@201174|Actinobacteria,4EUMU@85013|Frankiales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158463_k127_3871967_9	1123023.JIAI01000002_gene5142	7.857e-126	413.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DXVD@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigG	GO:0001101,GO:0001666,GO:0006950,GO:0008150,GO:0009415,GO:0009628,GO:0010035,GO:0036293,GO:0042221,GO:0050896,GO:0070482,GO:1901700	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2,SnoaL_4
SRR25158463_k127_3871967_19	479435.Kfla_2533	2.117e-72	259.0	2BW09@1|root,32QYN@2|Bacteria,2IHGH@201174|Actinobacteria,4DUZS@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3871967_0	1380370.JIBA01000011_gene3094	1.619e-248	783.0	COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria,4FEM9@85021|Intrasporangiaceae	201174|Actinobacteria	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158463_k127_3871967_26	1089455.MOPEL_029_01210	1.035e-36	143.0	COG3832@1|root,COG3832@2|Bacteria,2GSBV@201174|Actinobacteria,4F6ZH@85018|Dermatophilaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_3871967_30	1380370.JIBA01000004_gene2300	5.638e-13	81.0	2DRPJ@1|root,33CGW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3871967_4	1172188.KB911822_gene746	2.344e-149	496.0	COG0768@1|root,COG0768@2|Bacteria,2GJAM@201174|Actinobacteria,4FEVD@85021|Intrasporangiaceae	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	pbp2B	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158463_k127_3871967_6	479433.Caci_2641	1.157e-141	461.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158463_k127_3871967_31	1408813.AYMG01000046_gene4797	6.482e-12	80.0	COG1361@1|root,COG5492@1|root,COG1361@2|Bacteria,COG5492@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG
SRR25158463_k127_3871967_16	234267.Acid_3219	3.183e-79	301.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3871967_12	67373.JOBF01000012_gene3987	3.123e-107	365.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase, class I	aecD	-	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158463_k127_3871967_10	105422.BBPM01000014_gene3185	2.767e-125	409.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria,2NGKX@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix proteins, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158463_k127_3871967_5	1380370.JIBA01000011_gene3098	2.042e-145	468.0	COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,4FEQ7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SRR25158463_k127_3871967_3	1386089.N865_21785	2.213e-153	487.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,4FFDQ@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158463_k127_3871967_27	1123251.ATWM01000001_gene579	1.03e-30	134.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria,4FH16@85021|Intrasporangiaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	glpE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158463_k127_3871967_25	710696.Intca_0131	6.032e-37	139.0	COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4FF4R@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the pyridoxine kinase family	pdxY	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
SRR25158463_k127_3891014_2	1132441.KI519455_gene3145	1.593e-80	274.0	COG4821@1|root,COG4821@2|Bacteria,2GY6Q@201174|Actinobacteria,1WAKM@1268|Micrococcaceae	201174|Actinobacteria	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR25158463_k127_3891014_1	1121372.AULK01000006_gene1477	7.875e-117	384.0	COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria,4FM19@85023|Microbacteriaceae	201174|Actinobacteria	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
SRR25158463_k127_3891014_0	1380390.JIAT01000009_gene2254	1.374e-144	479.0	COG4934@1|root,COG4934@2|Bacteria,2GMZ8@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase S53	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_S8
SRR25158463_k127_3891014_3	1298863.AUEP01000002_gene1417	1.712e-72	248.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4DV29@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_3891014_4	1123065.ATWL01000009_gene1009	6.36e-12	66.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria	201174|Actinobacteria	K	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_3894855_4	1193181.BN10_1060022	2.393e-70	244.0	COG0642@1|root,COG2205@2|Bacteria,2GMB9@201174|Actinobacteria,4FE99@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158463_k127_3894855_2	1121017.AUFG01000014_gene1981	4.568e-92	313.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4FEGB@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158463_k127_3894855_5	1386089.N865_11195	1.086e-59	208.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4FGPK@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158463_k127_3894855_7	1386089.N865_11190	8.645e-26	113.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4FHQM@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158463_k127_3894855_1	1184609.KILIM_034_00200	3.311e-99	335.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4F6SW@85018|Dermatophilaceae	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158463_k127_3894855_0	1386089.N865_11180	1.972e-137	451.0	COG0477@1|root,COG2814@2|Bacteria,2GK22@201174|Actinobacteria,4FEEC@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3894855_6	247156.NFA_3250	4.862e-56	202.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,4G19A@85025|Nocardiaceae	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158463_k127_3894855_3	1172188.KB911822_gene888	1.373e-78	276.0	COG0753@1|root,COG0753@2|Bacteria,2GITN@201174|Actinobacteria,4FE33@85021|Intrasporangiaceae	201174|Actinobacteria	P	Serves to protect cells from the toxic effects of hydrogen peroxide	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
SRR25158463_k127_3897347_7	926550.CLDAP_29200	1.422e-38	157.0	COG1647@1|root,COG1647@2|Bacteria	2|Bacteria	M	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158463_k127_3897347_1	1386089.N865_06750	7.039e-275	855.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4FEPZ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158463_k127_3897347_3	1172188.KB911821_gene1570	6.565e-129	413.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4FF1P@85021|Intrasporangiaceae	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158463_k127_3897347_8	1123269.NX02_10705	1.515e-30	129.0	COG0847@1|root,COG0847@2|Bacteria,1RDF2@1224|Proteobacteria,2U73W@28211|Alphaproteobacteria,2K558@204457|Sphingomonadales	204457|Sphingomonadales	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
SRR25158463_k127_3897347_5	1385518.N798_16385	3.264e-57	208.0	COG0406@1|root,COG0406@2|Bacteria,2HXID@201174|Actinobacteria,4FH0Q@85021|Intrasporangiaceae	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158463_k127_3897347_6	479435.Kfla_2374	4.713e-41	162.0	COG3871@1|root,COG3871@2|Bacteria,2GWY2@201174|Actinobacteria,4DRER@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_3897347_2	1385518.N798_07040	1.932e-158	520.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4FG60@85021|Intrasporangiaceae	201174|Actinobacteria	E	gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158463_k127_3897347_0	1193181.BN10_1170026	0.0	1052.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,4FEHX@85021|Intrasporangiaceae	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158463_k127_3897347_9	1172188.KB911821_gene1574	1.347e-24	112.0	COG1366@1|root,COG1366@2|Bacteria,2HXI9@201174|Actinobacteria,4FH05@85021|Intrasporangiaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158463_k127_3897347_4	1172188.KB911821_gene1575	1.579e-102	337.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4FFXI@85021|Intrasporangiaceae	201174|Actinobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0008150,GO:0040007	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158463_k127_3899562_1	1122622.ATWJ01000008_gene2886	1.073e-196	641.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4FEFT@85021|Intrasporangiaceae	201174|Actinobacteria	K	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR25158463_k127_3899562_0	1385519.N801_19700	4.431e-243	757.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4FFKA@85021|Intrasporangiaceae	201174|Actinobacteria	C	NADPH quinone reductase	ccr	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158463_k127_3899562_2	1386089.N865_06730	5.92e-144	467.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4FF6V@85021|Intrasporangiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158463_k127_3899562_3	1121017.AUFG01000001_gene3130	1.349e-85	287.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GNDC@201174|Actinobacteria,4FEWT@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the synthesis of xanthosine monophosphate by the NAD dependent oxidation of inosine monophosphate	guaB1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158463_k127_3912066_2	1089544.KB912942_gene7328	1.217e-72	252.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4E1RF@85010|Pseudonocardiales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158463_k127_3912066_6	1122138.AQUZ01000087_gene1178	2.782e-09	67.0	2EN0B@1|root,33FNI@2|Bacteria,2GZRB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3912066_0	1298863.AUEP01000003_gene2994	2.221e-166	553.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DT6E@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_3912066_4	1122609.AUGT01000009_gene3210	3.439e-57	206.0	COG1309@1|root,COG1309@2|Bacteria,2IP3P@201174|Actinobacteria,4DSN9@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_3912066_1	1463901.JOIY01000003_gene1245	1.08e-80	278.0	COG0491@1|root,COG0491@2|Bacteria,2GMSA@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase	ytnP_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158463_k127_3912066_7	269800.Tfu_0837	1.369e-07	60.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158463_k127_3912066_5	710696.Intca_0281	1.189e-15	81.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4FF90@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
SRR25158463_k127_39334_14	1385518.N798_04290	7.646e-63	222.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4FE94@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158463_k127_39334_7	1380370.JIBA01000014_gene1881	5.134e-128	418.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4FE4N@85021|Intrasporangiaceae	201174|Actinobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158463_k127_39334_13	1313172.YM304_25350	8.377e-77	259.0	COG2236@1|root,COG2236@2|Bacteria,2GN86@201174|Actinobacteria	201174|Actinobacteria	F	phosphoribosyltransferase	gpt	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158463_k127_39334_21	1306174.JODP01000007_gene2551	2.513e-46	172.0	COG0346@1|root,COG0346@2|Bacteria,2I9G1@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_39334_10	1123023.JIAI01000010_gene8600	7.407e-120	392.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4DYQA@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158463_k127_39334_22	1043205.AFYF01000022_gene701	1.816e-42	173.0	COG1219@1|root,COG1219@2|Bacteria,2IFD9@201174|Actinobacteria,4FHJY@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_39334_19	1206726.BAFV01000072_gene5030	9.338e-47	171.0	COG3324@1|root,COG3324@2|Bacteria,2IM88@201174|Actinobacteria,4G1HI@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158463_k127_39334_5	675635.Psed_3759	8.941e-139	453.0	COG2271@1|root,COG2271@2|Bacteria,2I3QH@201174|Actinobacteria,4E29W@85010|Pseudonocardiales	201174|Actinobacteria	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158463_k127_39334_16	1713.JOFV01000003_gene1659	4.877e-57	203.0	COG4803@1|root,COG4803@2|Bacteria,2IHYU@201174|Actinobacteria,4F1DQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158463_k127_39334_0	1298863.AUEP01000003_gene2773	1.411e-236	745.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DPPG@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158463_k127_39334_3	479432.Sros_7423	2.325e-143	462.0	COG0596@1|root,COG0596@2|Bacteria,2I99I@201174|Actinobacteria,4EFS4@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	dhaA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009410,GO:0009987,GO:0016020,GO:0016787,GO:0016824,GO:0018786,GO:0019120,GO:0030312,GO:0042178,GO:0042197,GO:0042206,GO:0042221,GO:0044237,GO:0044248,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:1901575	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158463_k127_39334_23	1298860.AUEM01000012_gene132	4.892e-41	166.0	COG0640@1|root,COG0640@2|Bacteria,2IKWF@201174|Actinobacteria,4FQ2R@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158463_k127_39334_18	1452535.JARD01000009_gene1474	8.911e-54	210.0	COG3832@1|root,COG3832@2|Bacteria,2ISCU@201174|Actinobacteria,4FQDS@85023|Microbacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_39334_6	313589.JNB_12663	2.085e-138	451.0	COG0477@1|root,COG2814@2|Bacteria,2GN78@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
SRR25158463_k127_39334_20	1120949.KB903328_gene8978	1.122e-46	177.0	COG1902@1|root,COG1902@2|Bacteria,2IHUT@201174|Actinobacteria	201174|Actinobacteria	C	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158463_k127_39334_4	1179773.BN6_56520	3.04e-141	464.0	COG4403@1|root,COG4403@2|Bacteria,2IBX5@201174|Actinobacteria,4E8YR@85010|Pseudonocardiales	201174|Actinobacteria	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
SRR25158463_k127_39334_9	1380370.JIBA01000014_gene1876	2.582e-120	391.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4FE89@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158463_k127_39334_12	1386089.N865_10125	1.644e-89	298.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4FF1S@85021|Intrasporangiaceae	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158463_k127_39334_11	367299.JOEE01000004_gene1199	4.363e-91	309.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4FEKX@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158463_k127_39334_15	1172188.KB911820_gene2115	1.405e-62	228.0	COG2334@1|root,COG2334@2|Bacteria,2GQU8@201174|Actinobacteria,4FG7U@85021|Intrasporangiaceae	201174|Actinobacteria	S	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158463_k127_39334_1	1386089.N865_10110	1.745e-206	649.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4FFMX@85021|Intrasporangiaceae	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158463_k127_39334_17	1120950.KB892746_gene3485	4.542e-55	202.0	COG3154@1|root,COG3154@2|Bacteria,2INVN@201174|Actinobacteria,4DSBS@85009|Propionibacteriales	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158463_k127_39334_2	1305732.JAGG01000001_gene2308	1.192e-187	603.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4FKF5@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158463_k127_39334_8	1121017.AUFG01000020_gene2341	4.952e-124	406.0	COG1611@1|root,COG1611@2|Bacteria,2GPA4@201174|Actinobacteria,4FETS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Rossmann fold nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
SRR25158463_k127_3938205_13	388051.AUFE01000004_gene919	2.403e-08	55.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VNJM@28216|Betaproteobacteria,1K04U@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Long-chain fatty acid--CoA ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_3938205_3	446462.Amir_5665	4.235e-123	407.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4DYUC@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
SRR25158463_k127_3938205_12	367299.JOEE01000005_gene3479	2.806e-34	146.0	COG2268@1|root,COG2268@2|Bacteria,2GKTJ@201174|Actinobacteria,4FF1T@85021|Intrasporangiaceae	201174|Actinobacteria	S	Cellulose-binding protein	abpS	-	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158463_k127_3938205_11	1232429.CBLL010000094_gene1299	1.029e-48	180.0	COG0823@1|root,COG4338@1|root,COG0823@2|Bacteria,COG4338@2|Bacteria,2GRR2@201174|Actinobacteria,1W9MB@1268|Micrococcaceae	201174|Actinobacteria	U	Protein of unknown function (DUF3253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3253
SRR25158463_k127_3938205_2	1240349.ANGC01000003_gene2147	7.773e-152	486.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4G6CB@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_3938205_0	1429046.RR21198_4229	6.309e-177	565.0	COG2124@1|root,COG2124@2|Bacteria,2I2QQ@201174|Actinobacteria,4FVMH@85025|Nocardiaceae	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158463_k127_3938205_9	1382356.JQMP01000003_gene1695	7.462e-75	282.0	COG0657@1|root,COG0657@2|Bacteria,2GBCM@200795|Chloroflexi,27YSU@189775|Thermomicrobia	189775|Thermomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158463_k127_3938205_7	1268303.RHODMAR_1486	3.501e-93	324.0	COG0683@1|root,COG0683@2|Bacteria,2IBQR@201174|Actinobacteria	201174|Actinobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158463_k127_3938205_4	1380356.JNIK01000002_gene4764	7.696e-110	362.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_3938205_8	1380356.JNIK01000002_gene4763	6.724e-89	316.0	COG4177@1|root,COG4177@2|Bacteria,2ICU5@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158463_k127_3938205_6	1380356.JNIK01000002_gene4762	5.028e-97	325.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
SRR25158463_k127_3938205_10	34506.g3030	4.095e-52	194.0	COG0488@1|root,KOG0927@2759|Eukaryota	2759|Eukaryota	T	ATPase activity	-	-	-	ko:K15073	-	-	-	-	ko00000,ko04121	-	-	-	ABC_tran,DHDPS
SRR25158463_k127_3938205_5	1268303.RHODMAR_1524	9.691e-99	328.0	COG2186@1|root,COG2186@2|Bacteria,2ICDJ@201174|Actinobacteria,4FWZV@85025|Nocardiaceae	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158463_k127_3938205_1	1343740.M271_00550	8.937e-170	541.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_3945750_8	1193181.BN10_1300016	4.492e-19	87.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3945750_9	1196031.ALEG01000035_gene864	1.249e-08	57.0	29TAG@1|root,30EHH@2|Bacteria,1UCJJ@1239|Firmicutes,4IP1R@91061|Bacilli,1ZP94@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3945750_1	1380370.JIBA01000017_gene2806	3.868e-209	677.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4FEQZ@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158463_k127_3945750_6	1193181.BN10_1060007	4.157e-83	289.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4FGQJ@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the DNA glycosylase MPG family	alkA	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158463_k127_3945750_0	1385521.N803_00030	1.004e-243	760.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4FF12@85021|Intrasporangiaceae	201174|Actinobacteria	E	Argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158463_k127_3945750_7	1184607.AUCHE_01_00030	3.24e-45	170.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4F6XH@85018|Dermatophilaceae	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158463_k127_3945750_3	1385519.N801_15665	6.199e-159	518.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4FE84@85021|Intrasporangiaceae	201174|Actinobacteria	E	acetylornithine aminotransferase	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158463_k127_3945750_4	1210046.B277_05486	7.104e-156	497.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4FFJU@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158463_k127_3945750_2	1380370.JIBA01000017_gene2812	2.024e-175	571.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4FFF4@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158463_k127_3945750_5	595593.JREV01000022_gene1514	7.653e-114	376.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,1W82P@1268|Micrococcaceae	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158463_k127_3961779_3	1211815.CBYP010000063_gene1897	4.409e-123	414.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4ETJC@85013|Frankiales	201174|Actinobacteria	S	Saccharopine dehydrogenase	LYS1	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030312,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K12445	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	Sacchrp_dh_NADP
SRR25158463_k127_3961779_0	367299.JOEE01000004_gene1421	5.636e-222	696.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4FEHQ@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158463_k127_3961779_5	1385520.N802_14010	1.117e-72	250.0	2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4FG05@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3043)	-	GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	-	-	-	-	-	-	-	-	-	DUF3043
SRR25158463_k127_3961779_2	1172188.KB911827_gene4329	3.855e-165	531.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4FEK3@85021|Intrasporangiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158463_k127_3961779_1	953739.SVEN_0303	5.799e-166	538.0	COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	lmrB	-	-	ko:K18926	-	M00715	-	-	ko00000,ko00002,ko02000	2.A.1.3.30	-	-	MFS_1
SRR25158463_k127_3961779_7	1172188.KB911827_gene4328	2.129e-19	90.0	2EFWK@1|root,339NW@2|Bacteria,2IQXQ@201174|Actinobacteria,4FHT5@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3961779_6	1172188.KB911827_gene4327	1.654e-52	197.0	2E883@1|root,332M6@2|Bacteria,2I8J4@201174|Actinobacteria,4FG82@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_3961779_4	1380370.JIBA01000018_gene410	7.027e-89	304.0	COG0619@1|root,COG0619@2|Bacteria,2GKHK@201174|Actinobacteria,4FEYI@85021|Intrasporangiaceae	201174|Actinobacteria	P	cobalt ABC transporter, permease	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158463_k127_396338_1	1386089.N865_12115	2.492e-220	685.0	COG3185@1|root,COG3185@2|Bacteria,2GNF0@201174|Actinobacteria,4FEYX@85021|Intrasporangiaceae	201174|Actinobacteria	E	4-hydroxyphenylpyruvate dioxygenase	hpd	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158463_k127_396338_4	1386089.N865_12125	2.526e-63	235.0	COG1714@1|root,COG1714@2|Bacteria,2HXE4@201174|Actinobacteria,4FGCN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2510)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,RDD
SRR25158463_k127_396338_5	1172188.KB911824_gene3238	3.395e-63	225.0	COG1414@1|root,COG1414@2|Bacteria,2GMEA@201174|Actinobacteria,4FG5K@85021|Intrasporangiaceae	201174|Actinobacteria	K	IclR family transcriptional regulator	sdrB	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
SRR25158463_k127_396338_2	1386089.N865_12130	2.388e-182	578.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria,4FF35@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
SRR25158463_k127_396338_0	1386089.N865_12140	8.29e-238	741.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,4FET6@85021|Intrasporangiaceae	201174|Actinobacteria	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158463_k127_396338_3	1380370.JIBA01000017_gene3003	9.931e-68	242.0	COG2852@1|root,COG2852@2|Bacteria,2GNZQ@201174|Actinobacteria,4FG2I@85021|Intrasporangiaceae	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158463_k127_3964627_3	710696.Intca_3046	5.049e-83	285.0	COG1105@1|root,COG1105@2|Bacteria	2|Bacteria	H	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158463_k127_3964627_1	710696.Intca_3047	5.244e-116	389.0	COG2152@1|root,COG2152@2|Bacteria,2HNS8@201174|Actinobacteria,4FJPX@85021|Intrasporangiaceae	201174|Actinobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
SRR25158463_k127_3964627_4	1306174.JODP01000028_gene138	3.483e-72	246.0	COG5637@1|root,COG5637@2|Bacteria,2GMK7@201174|Actinobacteria	201174|Actinobacteria	D	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158463_k127_3964627_6	479435.Kfla_6369	1.499e-23	108.0	COG5485@1|root,COG5485@2|Bacteria,2IKXY@201174|Actinobacteria	201174|Actinobacteria	S	Ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158463_k127_3964627_5	1380370.JIBA01000011_gene3246	3.975e-47	180.0	COG1073@1|root,COG1073@2|Bacteria,2HXYG@201174|Actinobacteria,4FIIA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158463_k127_3964627_2	356851.JOAN01000018_gene5632	1.731e-89	302.0	COG0631@1|root,COG0631@2|Bacteria,2GMVJ@201174|Actinobacteria,4DIN0@85008|Micromonosporales	201174|Actinobacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
SRR25158463_k127_3964627_7	1380354.JIAN01000005_gene2289	6.64e-22	101.0	COG3795@1|root,COG3795@2|Bacteria,2IHYC@201174|Actinobacteria	201174|Actinobacteria	S	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_3964627_8	1380354.JIAN01000005_gene2289	4.718e-17	91.0	COG3795@1|root,COG3795@2|Bacteria,2IHYC@201174|Actinobacteria	201174|Actinobacteria	S	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_3964627_0	1380354.JIAN01000005_gene2290	1.381e-200	631.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_3964627_9	1385519.N801_13725	1.426e-16	81.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4FHAB@85021|Intrasporangiaceae	201174|Actinobacteria	T	suppressor protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158463_k127_397288_7	512565.AMIS_22340	3.809e-13	69.0	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria,4DGWX@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158463_k127_397288_5	391593.RCCS2_05694	6.202e-27	123.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2U5CF@28211|Alphaproteobacteria,2P2BX@2433|Roseobacter	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158463_k127_397288_1	1172188.KB911822_gene763	2.086e-192	621.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4FJ6N@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Lipase_GDSL_2
SRR25158463_k127_397288_6	1283283.ATXA01000003_gene1405	5.355e-26	109.0	2E46R@1|root,33FF6@2|Bacteria,2GS7S@201174|Actinobacteria,4EWYH@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_397288_2	313589.JNB_05185	1.029e-85	287.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4FF00@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158463_k127_397288_3	47716.JOFH01000003_gene706	3.034e-69	242.0	COG0572@1|root,COG0572@2|Bacteria,2I9H4@201174|Actinobacteria	201174|Actinobacteria	F	Fructose transport system kinase	frcK	-	-	-	-	-	-	-	-	-	-	-	ArgK,PRK
SRR25158463_k127_397288_0	1386089.N865_15715	6.604e-263	819.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FEX6@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	AMP-binding protein	fadD5	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_4002376_5	1306174.JODP01000005_gene1553	1.562e-13	77.0	2DDDG@1|root,2ZHM1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4002376_1	367299.JOEE01000011_gene3167	3.122e-153	520.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0000166,GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008289,GO:0008610,GO:0009058,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0010817,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0036094,GO:0040007,GO:0042445,GO:0042446,GO:0042562,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0070401,GO:0071704,GO:0097159,GO:0099130,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903924	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158463_k127_4002376_0	1121946.AUAX01000032_gene495	4.546e-213	674.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DBSZ@85008|Micromonosporales	201174|Actinobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
SRR25158463_k127_4002376_4	479432.Sros_0343	8.028e-22	96.0	2CGGQ@1|root,32S3Z@2|Bacteria,2IQ59@201174|Actinobacteria,4EKB1@85012|Streptosporangiales	201174|Actinobacteria	L	Protein of unknown function (DUF3140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3140
SRR25158463_k127_4002376_3	675635.Psed_0710	1.967e-37	154.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4E5JA@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158463_k127_4002376_2	1283283.ATXA01000017_gene3732	3.354e-113	369.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4ES74@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158463_k127_4011993_4	1172188.KB911823_gene649	2.026e-91	302.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4FE9F@85021|Intrasporangiaceae	201174|Actinobacteria	EH	Class IV aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158463_k127_4011993_6	1380370.JIBA01000013_gene1341	3.367e-80	271.0	2E4Q9@1|root,32ZIV@2|Bacteria,2II59@201174|Actinobacteria,4FHDW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158463_k127_4011993_7	1386089.N865_15225	4.577e-51	189.0	291E7@1|root,2ZP12@2|Bacteria,2I75R@201174|Actinobacteria,4FH3I@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4011993_5	1386089.N865_15230	1.564e-81	274.0	COG1853@1|root,COG1853@2|Bacteria,2IP6R@201174|Actinobacteria,4FGTR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158463_k127_4011993_0	1172188.KB911823_gene642	1.168e-236	749.0	COG0183@1|root,COG0183@2|Bacteria,2GJI8@201174|Actinobacteria,4FFR2@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadI	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158463_k127_4011993_1	1172188.KB911823_gene641	1.245e-216	683.0	COG1028@1|root,COG1028@2|Bacteria,2GJCZ@201174|Actinobacteria,4FFTI@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_4011993_2	1172188.KB911823_gene640	3.66e-147	470.0	COG2030@1|root,COG2030@2|Bacteria,2GNQQ@201174|Actinobacteria,4FFHW@85021|Intrasporangiaceae	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158463_k127_4014971_0	1385518.N798_15820	0.0	2114.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4FEQ8@85021|Intrasporangiaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158463_k127_4014971_3	1386089.N865_16485	8.535e-116	380.0	COG0266@1|root,COG0266@2|Bacteria,2GKCW@201174|Actinobacteria,4FEMR@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA glycosylase	nei	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158463_k127_4014971_7	710687.KI912270_gene718	1.148e-46	178.0	2DS2T@1|root,33E9A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158463_k127_4014971_9	935839.JAGJ01000003_gene1566	6.945e-37	152.0	COG0346@1|root,COG0346@2|Bacteria,2IIMV@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,TetR_N
SRR25158463_k127_4014971_12	243231.GSU0747	4.189e-21	102.0	COG4430@1|root,COG4430@2|Bacteria,1NASK@1224|Proteobacteria	1224|Proteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158463_k127_4014971_10	1120960.ATXG01000001_gene1113	1.661e-36	143.0	COG0251@1|root,COG0251@2|Bacteria,2HTA6@201174|Actinobacteria,4FSQ9@85023|Microbacteriaceae	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158463_k127_4014971_6	312284.A20C1_07658	1.648e-47	177.0	COG5516@1|root,COG5516@2|Bacteria,2GP70@201174|Actinobacteria	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158463_k127_4014971_2	1386089.N865_17260	1.921e-132	436.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4FF0A@85021|Intrasporangiaceae	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158463_k127_4014971_11	1193181.BN10_680016	5.335e-30	123.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,4FHCE@85021|Intrasporangiaceae	201174|Actinobacteria	K	XRE family transcriptional regulator	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158463_k127_4014971_8	1157637.KB892116_gene83	9.325e-46	172.0	COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
SRR25158463_k127_4014971_5	1380370.JIBA01000014_gene1774	8.487e-69	246.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4FGM3@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158463_k127_4014971_1	1380370.JIBA01000014_gene1775	7.211e-220	690.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,4FEHN@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158463_k127_4014971_4	526225.Gobs_2447	1.188e-79	269.0	COG2355@1|root,COG2355@2|Bacteria,2GN82@201174|Actinobacteria,4ERTF@85013|Frankiales	201174|Actinobacteria	E	Membrane dipeptidase (Peptidase family M19)	Dpep	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158463_k127_4019239_1	743718.Isova_2944	6.713e-237	745.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4F5CD@85017|Promicromonosporaceae	201174|Actinobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158463_k127_4019239_7	710696.Intca_2232	1.473e-75	272.0	COG1477@1|root,COG1477@2|Bacteria,2GN6F@201174|Actinobacteria,4FE9R@85021|Intrasporangiaceae	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158463_k127_4019239_9	710696.Intca_2233	1.248e-31	132.0	COG3976@1|root,COG3976@2|Bacteria,2GTTI@201174|Actinobacteria,4FGNQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
SRR25158463_k127_4019239_3	1385519.N801_13220	2.894e-173	561.0	COG1018@1|root,COG1018@2|Bacteria,2HE37@201174|Actinobacteria,4FENU@85021|Intrasporangiaceae	201174|Actinobacteria	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Ferric_reduct,NAD_binding_1
SRR25158463_k127_4019239_4	1385518.N798_04120	5.899e-116	378.0	COG0730@1|root,COG0730@2|Bacteria,2GMNQ@201174|Actinobacteria,4FFDD@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158463_k127_4019239_6	1121017.AUFG01000020_gene2322	3.133e-90	325.0	COG1011@1|root,COG1011@2|Bacteria,2HX5F@201174|Actinobacteria,4FEU4@85021|Intrasporangiaceae	201174|Actinobacteria	S	Hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158463_k127_4019239_0	367299.JOEE01000004_gene1226	5.209e-309	960.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4FETC@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158463_k127_4019239_8	1386089.N865_16230	1.587e-41	160.0	COG4270@1|root,COG4270@2|Bacteria,2IQJ5@201174|Actinobacteria,4FGT4@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158463_k127_4019239_5	1380370.JIBA01000012_gene3576	3.118e-103	346.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria,4FFV8@85021|Intrasporangiaceae	201174|Actinobacteria	K	LacI family transcription regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_4019239_2	1386089.N865_16210	1.278e-218	687.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4FEY2@85021|Intrasporangiaceae	201174|Actinobacteria	G	With XylFH is part of the high affinity xylose ABC transporter	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
SRR25158463_k127_4028310_1	1382306.JNIM01000001_gene3779	1.746e-132	464.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158463_k127_4028310_0	298653.Franean1_3799	2.309e-137	472.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I5UU@201174|Actinobacteria,4EXD6@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158463_k127_4028310_4	1110697.NCAST_17_00520	1.249e-15	84.0	COG2353@1|root,COG2353@2|Bacteria,2GT6P@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158463_k127_4028310_3	1122602.ATXP01000003_gene1669	2.586e-81	274.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,1W8XQ@1268|Micrococcaceae	201174|Actinobacteria	J	Methyltransferase	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
SRR25158463_k127_4028310_2	1386089.N865_17200	2.487e-82	278.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4FEDM@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158463_k127_4038424_3	1193181.BN10_470019	2.591e-60	219.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4FGIJ@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158463_k127_4038424_0	1385519.N801_05925	2.358e-166	533.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4FEFM@85021|Intrasporangiaceae	201174|Actinobacteria	E	Aminotransferase	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158463_k127_4038424_2	1043205.AFYF01000058_gene2476	4.911e-69	234.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4FGN1@85021|Intrasporangiaceae	201174|Actinobacteria	C	ferredoxin	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158463_k127_4038424_1	1386089.N865_11720	1.082e-74	281.0	COG0454@1|root,COG0456@2|Bacteria,2H5WU@201174|Actinobacteria,4FGPF@85021|Intrasporangiaceae	201174|Actinobacteria	K	Acetyltransferase	-	-	2.3.1.1	ko:K22476	ko00220,ko01210,ko01230,map00220,map01210,map01230	-	R00259	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,FR47
SRR25158463_k127_4063999_1	1386089.N865_14430	4.677e-247	774.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,4FEF6@85021|Intrasporangiaceae	201174|Actinobacteria	L	Contains 3'-5'exonuclease domain	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158463_k127_4063999_5	710696.Intca_1977	2.126e-12	70.0	29QCV@1|root,30BC3@2|Bacteria,2GVJ2@201174|Actinobacteria,4FHPP@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4063999_4	1193181.BN10_360028	2.509e-49	194.0	COG0308@1|root,COG0308@2|Bacteria,2GK29@201174|Actinobacteria,4FJZW@85021|Intrasporangiaceae	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4063999_0	1386089.N865_19525	1.83e-262	834.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4FE72@85021|Intrasporangiaceae	201174|Actinobacteria	I	Long-chain fatty acid--CoA ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158463_k127_4063999_2	1386089.N865_19520	4.309e-64	242.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4FGJQ@85021|Intrasporangiaceae	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158463_k127_4063999_3	1385520.N802_14180	7.131e-60	211.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158463_k127_4085529_4	367299.JOEE01000005_gene3495	4.62e-76	257.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4FEII@85021|Intrasporangiaceae	201174|Actinobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158463_k127_4085529_8	710696.Intca_1627	8.622e-39	157.0	2E71H@1|root,331K6@2|Bacteria,2I18I@201174|Actinobacteria,4FHM5@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_6
SRR25158463_k127_4085529_3	1385519.N801_18820	1.576e-77	267.0	2A4DI@1|root,30SZC@2|Bacteria,2GJJM@201174|Actinobacteria,4FESI@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4085529_2	1172188.KB911825_gene3698	1.261e-86	310.0	COG2755@1|root,COG2755@2|Bacteria,2HXHN@201174|Actinobacteria,4FGWU@85021|Intrasporangiaceae	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158463_k127_4085529_1	710696.Intca_1629	4.01e-121	402.0	COG2807@1|root,COG2807@2|Bacteria,2GP5W@201174|Actinobacteria,4FFXQ@85021|Intrasporangiaceae	201174|Actinobacteria	P	MFS transporter	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
SRR25158463_k127_4085529_5	1121017.AUFG01000004_gene3211	3.304e-72	254.0	29KMP@1|root,307IZ@2|Bacteria,2GWIU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
SRR25158463_k127_4085529_7	367299.JOEE01000005_gene3499	1.751e-64	228.0	COG0572@1|root,COG0572@2|Bacteria,2HQC8@201174|Actinobacteria,4FGFG@85021|Intrasporangiaceae	201174|Actinobacteria	F	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,Cytidylate_kin
SRR25158463_k127_4085529_0	1172188.KB911823_gene338	1.431e-130	435.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4FE4T@85021|Intrasporangiaceae	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158463_k127_4085529_6	1172188.KB911823_gene339	2.206e-67	235.0	COG0243@1|root,COG0243@2|Bacteria,2GJ62@201174|Actinobacteria,4FEZR@85021|Intrasporangiaceae	201174|Actinobacteria	C	molybdopterin cofactor binding	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158463_k127_4085529_9	1386089.N865_00790	0.000737	48.0	COG3981@1|root,COG3981@2|Bacteria,2IGK9@201174|Actinobacteria,4FH12@85021|Intrasporangiaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158463_k127_4087844_2	1172185.KB911514_gene4384	1.617e-114	391.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4FY2A@85025|Nocardiaceae	201174|Actinobacteria	CG	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158463_k127_4087844_6	526225.Gobs_2653	8.814e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,2IR68@201174|Actinobacteria,4EVPP@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_4087844_5	1386089.N865_20170	5.609e-45	180.0	COG4243@1|root,COG4243@2|Bacteria,2HGRN@201174|Actinobacteria,4FGUP@85021|Intrasporangiaceae	201174|Actinobacteria	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158463_k127_4087844_3	1122138.AQUZ01000098_gene7765	1.029e-70	250.0	arCOG03842@1|root,30WW9@2|Bacteria,2IDJ1@201174|Actinobacteria,4DRRZ@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF929
SRR25158463_k127_4087844_1	1172188.KB911830_gene3827	1.512e-149	479.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4FFG5@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158463_k127_4087844_0	1386089.N865_20185	1.892e-234	732.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4FECH@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158463_k127_4087844_4	446466.Cfla_1116	4.229e-61	221.0	29525@1|root,2ZSEY@2|Bacteria,2IKD7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_40947_1	1386089.N865_12475	5.17e-114	370.0	COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4FEA1@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA topoisomerase (ATP-hydrolyzing)	gyrB2	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158463_k127_40947_5	1123258.AQXZ01000014_gene4805	5.575e-49	187.0	COG2020@1|root,COG2020@2|Bacteria,2HHZT@201174|Actinobacteria,4G1XJ@85025|Nocardiaceae	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
SRR25158463_k127_40947_6	590998.Celf_0141	1.583e-47	175.0	COG0346@1|root,COG0346@2|Bacteria,2IMGZ@201174|Actinobacteria,4F2GZ@85016|Cellulomonadaceae	201174|Actinobacteria	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158463_k127_40947_0	1380370.JIBA01000013_gene1178	1.166e-145	467.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FFG2@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158463_k127_40947_2	1380370.JIBA01000013_gene1179	5.889e-88	313.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4FE7H@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158463_k127_40947_7	1380370.JIBA01000013_gene1180	4.752e-32	130.0	2DP0T@1|root,3302D@2|Bacteria,2I0W8@201174|Actinobacteria,4FGSH@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_40947_3	1172188.KB911827_gene4389	2.428e-82	291.0	COG2304@1|root,COG2304@2|Bacteria,2I9VM@201174|Actinobacteria,4FE4P@85021|Intrasporangiaceae	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158463_k127_40947_4	1172188.KB911827_gene4390	2.707e-76	282.0	COG2304@1|root,COG2304@2|Bacteria,2GJMP@201174|Actinobacteria,4FFSD@85021|Intrasporangiaceae	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SRR25158463_k127_4095316_7	1172188.KB911822_gene693	1.55e-53	193.0	COG4898@1|root,COG4898@2|Bacteria,2IKPX@201174|Actinobacteria,4FGZG@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
SRR25158463_k127_4095316_3	1209984.BN978_02174	3.792e-104	346.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,23DYB@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158463_k127_4095316_4	330084.JNYZ01000006_gene1292	2.284e-95	320.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria,4E9GI@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158463_k127_4095316_2	1209984.BN978_02172	8.733e-108	371.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,239FQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_4095316_1	1120948.KB903240_gene4003	2.113e-114	375.0	COG3965@1|root,COG3965@2|Bacteria,2HRDF@201174|Actinobacteria,4EAJ2@85010|Pseudonocardiales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158463_k127_4095316_6	479435.Kfla_5242	1.115e-86	301.0	COG1511@1|root,COG1511@2|Bacteria,2HEUW@201174|Actinobacteria,4DQY3@85009|Propionibacteriales	201174|Actinobacteria	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4095316_9	33876.JNXY01000024_gene4944	9.47e-43	165.0	COG1309@1|root,COG1309@2|Bacteria,2IIM0@201174|Actinobacteria,4DM5D@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158463_k127_4095316_0	67373.JOBF01000022_gene6618	1.266e-231	743.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158463_k127_4095316_5	67373.JOBF01000022_gene6620	2.805e-88	312.0	COG0476@1|root,COG0476@2|Bacteria,2HQ2F@201174|Actinobacteria	201174|Actinobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360	-	-	-	-	-	-	-	-	-	-	Nitroreductase,ThiF
SRR25158463_k127_4095316_8	479431.Namu_1270	2.119e-43	168.0	COG2304@1|root,COG2304@2|Bacteria,2GUB3@201174|Actinobacteria,4EV0R@85013|Frankiales	201174|Actinobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,VWA
SRR25158463_k127_4154456_1	1386089.N865_21175	2.885e-130	422.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4FETI@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_4154456_2	1380370.JIBA01000014_gene2089	2.586e-108	359.0	28JAE@1|root,2Z957@2|Bacteria,2IFSW@201174|Actinobacteria,4FFA7@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158463_k127_4154456_0	1172188.KB911821_gene1616	0.0	1947.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4FE2X@85021|Intrasporangiaceae	201174|Actinobacteria	C	part of alternative pathway from alpha-ketoglutarate to succinate	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158463_k127_4154456_3	1380370.JIBA01000014_gene2092	8.859e-104	351.0	COG2755@1|root,COG2755@2|Bacteria,2IA8J@201174|Actinobacteria,4FG1T@85021|Intrasporangiaceae	201174|Actinobacteria	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158463_k127_4154456_4	446466.Cfla_1212	1.109e-35	150.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria,4F2CN@85016|Cellulomonadaceae	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158463_k127_4158281_1	1449346.JQMO01000002_gene798	2.848e-05	47.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,2M4SI@2063|Kitasatospora	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C,NPCBM_assoc
SRR25158463_k127_4158281_0	1150398.JIBJ01000005_gene3343	9.632e-09	63.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	ko:K12513	-	-	-	-	ko00000,ko02044	-	-	-	TadE
SRR25158463_k127_4179254_3	136273.GY22_06845	4.886e-74	255.0	2AEJC@1|root,314EV@2|Bacteria,2GMTI@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158463_k127_4179254_2	1240349.ANGC01000006_gene1478	1.932e-78	267.0	COG1651@1|root,COG1651@2|Bacteria,2I2E4@201174|Actinobacteria,4FUGI@85025|Nocardiaceae	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158463_k127_4179254_4	1385519.N801_06635	1.994e-57	203.0	COG1846@1|root,COG1846@2|Bacteria,2IHTR@201174|Actinobacteria,4FHE5@85021|Intrasporangiaceae	201174|Actinobacteria	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
SRR25158463_k127_4179254_1	477641.MODMU_4613	1.236e-79	269.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4EV2A@85013|Frankiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158463_k127_4179254_0	1380370.JIBA01000012_gene3584	1.09e-163	520.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4FERZ@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	fgd_1	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_4179254_5	105425.BBPL01000015_gene2607	5.189e-18	87.0	COG0346@1|root,COG0346@2|Bacteria,2HTC1@201174|Actinobacteria,2NMQF@228398|Streptacidiphilus	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4181487_3	1172188.KB911823_gene563	3.332e-174	561.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,4FEVP@85021|Intrasporangiaceae	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iNJ661.Rv2051c	CN_hydrolase
SRR25158463_k127_4181487_8	1386089.N865_13260	5.996e-107	355.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4FF3E@85021|Intrasporangiaceae	201174|Actinobacteria	M	Dolichol-phosphate mannosyltransferase	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158463_k127_4181487_15	1121017.AUFG01000005_gene1065	3.936e-44	179.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4FHDA@85021|Intrasporangiaceae	201174|Actinobacteria	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
SRR25158463_k127_4181487_1	296591.Bpro_3578	1.593e-248	790.0	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,2VH0N@28216|Betaproteobacteria,4AAWX@80864|Comamonadaceae	28216|Betaproteobacteria	FH	PFAM permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR25158463_k127_4181487_13	1385521.N803_07965	1.945e-53	190.0	2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4FGZR@85021|Intrasporangiaceae	201174|Actinobacteria	K	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters	rbpA	GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RbpA
SRR25158463_k127_4181487_2	1380370.JIBA01000013_gene1419	5.093e-199	672.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4FEYW@85021|Intrasporangiaceae	201174|Actinobacteria	S	MFS transporter	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158463_k127_4181487_16	1380354.JIAN01000005_gene1870	3.189e-34	133.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4242,Guanylate_cyc
SRR25158463_k127_4181487_0	1298863.AUEP01000001_gene1057	9.179e-307	968.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DPBQ@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158463_k127_4181487_6	1386089.N865_12985	1.26e-126	421.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4FEI4@85021|Intrasporangiaceae	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158463_k127_4181487_5	28444.JODQ01000001_gene2609	5.306e-129	454.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR25158463_k127_4181487_4	1035308.AQYY01000002_gene405	1.141e-141	459.0	COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,248J3@186801|Clostridia,2606E@186807|Peptococcaceae	186801|Clostridia	P	PFAM Sodium calcium exchanger protein	cax	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158463_k127_4181487_12	1101188.KI912155_gene2113	3.275e-63	231.0	COG1073@1|root,COG1073@2|Bacteria,2I364@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158463_k127_4181487_11	1206726.BAFV01000070_gene4834	1.343e-77	264.0	COG0262@1|root,COG0262@2|Bacteria,2IFTI@201174|Actinobacteria,4G8T4@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_4181487_7	479431.Namu_0060	1.184e-112	368.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4ES0G@85013|Frankiales	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158463_k127_4181487_17	1120950.KB892812_gene7030	1.844e-25	123.0	COG0748@1|root,COG0748@2|Bacteria,2INF5@201174|Actinobacteria,4DSIG@85009|Propionibacteriales	201174|Actinobacteria	P	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_4181487_10	1120960.ATXG01000014_gene554	7.044e-94	324.0	28MY8@1|root,2ZEEV@2|Bacteria,2I3GD@201174|Actinobacteria,4FTRZ@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4181487_19	1123258.AQXZ01000017_gene4041	2.535e-13	83.0	2AYGA@1|root,31QJK@2|Bacteria,2IS7K@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158463_k127_4181487_14	1297570.MESS4_430005	6.736e-51	189.0	COG1280@1|root,COG1280@2|Bacteria,1RF1D@1224|Proteobacteria,2VG7N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158463_k127_4181487_9	1120960.ATXG01000017_gene1397	5.338e-98	326.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria,4FRYG@85023|Microbacteriaceae	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158463_k127_4181487_18	1380356.JNIK01000001_gene2101	4.243e-22	101.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EUDV@85013|Frankiales	201174|Actinobacteria	T	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR25158463_k127_4185771_8	1172188.KB911828_gene4049	2.233e-30	126.0	2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4FGM6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
SRR25158463_k127_4185771_9	1172188.KB911828_gene4048	3.729e-30	126.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria,4FHW3@85021|Intrasporangiaceae	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4185771_5	1385518.N798_04695	1.399e-63	227.0	28J4D@1|root,30NZ9@2|Bacteria,2I2E9@201174|Actinobacteria,4FGDW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3710)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3710
SRR25158463_k127_4185771_4	1172188.KB911828_gene4046	3.148e-68	236.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4FGNM@85021|Intrasporangiaceae	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158463_k127_4185771_6	313589.JNB_01795	1.718e-49	181.0	2ATJW@1|root,31J3Z@2|Bacteria,2IKN0@201174|Actinobacteria,4FGXK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
SRR25158463_k127_4185771_10	1172188.KB911828_gene4044	9.896e-09	60.0	2B1YW@1|root,31UFE@2|Bacteria,2GTXU@201174|Actinobacteria,4FHVZ@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4185771_1	710696.Intca_1938	1.003e-84	290.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4FGCP@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the inositol monophosphatase superfamily	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158463_k127_4185771_0	1386089.N865_12555	7.461e-170	543.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,4FEKH@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158463_k127_4185771_3	1172188.KB911828_gene4041	4.99e-77	265.0	COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4FGW3@85021|Intrasporangiaceae	201174|Actinobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
SRR25158463_k127_4185771_2	367299.JOEE01000008_gene402	8.246e-79	291.0	28PUQ@1|root,2ZCFK@2|Bacteria,2GNQM@201174|Actinobacteria,4FEVK@85021|Intrasporangiaceae	201174|Actinobacteria	S	DNA-binding protein	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	DUF3071
SRR25158463_k127_4185771_7	1123023.JIAI01000008_gene1493	6.734e-43	180.0	COG1024@1|root,COG1024@2|Bacteria,2IEXB@201174|Actinobacteria,4E3W4@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA3_1	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158463_k127_4203539_1	710696.Intca_1156	1.554e-237	739.0	COG1012@1|root,COG1012@2|Bacteria,2GJZE@201174|Actinobacteria,4FFQI@85021|Intrasporangiaceae	201174|Actinobacteria	C	Dehydrogenase	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158463_k127_4203539_4	397278.JOJN01000006_gene1048	7.354e-55	211.0	COG2267@1|root,COG2267@2|Bacteria,2I658@201174|Actinobacteria,4DVMH@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158463_k127_4203539_5	397278.JOJN01000006_gene1048	1.049e-50	199.0	COG2267@1|root,COG2267@2|Bacteria,2I658@201174|Actinobacteria,4DVMH@85009|Propionibacteriales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158463_k127_4203539_0	1089545.KB913037_gene1387	4.921e-317	984.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4DXUN@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,GSDH,PBP,RicinB_lectin_2,Ricin_B_lectin,fn3
SRR25158463_k127_4203539_6	1385520.N802_18325	4.41e-15	88.0	2DTCB@1|root,33JPI@2|Bacteria,2HXHG@201174|Actinobacteria,4FGW4@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4203539_3	479433.Caci_7582	1.538e-82	286.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria	201174|Actinobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158463_k127_4203539_2	1380370.JIBA01000014_gene2107	1.17e-207	655.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4FEF5@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	tgs3	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158463_k127_4207455_9	1385520.N802_05180	3.206e-34	141.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158463_k127_4207455_12	1380346.JNIH01000012_gene6870	9.899e-14	80.0	COG2197@1|root,COG2197@2|Bacteria,2IKTN@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158463_k127_4207455_0	479431.Namu_0811	1.208e-171	557.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4ESVV@85013|Frankiales	201174|Actinobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158463_k127_4207455_2	479431.Namu_0810	5.044e-101	332.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4EV96@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158463_k127_4207455_10	479431.Namu_0812	1.238e-28	129.0	2DYZ8@1|root,34BV6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_4207455_4	1246995.AFR_19715	4.15e-82	279.0	COG0807@1|root,COG0807@2|Bacteria,2GNS4@201174|Actinobacteria,4DAAG@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N,GTP_cyclohydro2
SRR25158463_k127_4207455_5	65497.JODV01000001_gene4033	5.134e-74	257.0	COG1985@1|root,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4E17G@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	ribG	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158463_k127_4207455_6	1172188.KB911820_gene3119	7.092e-71	253.0	COG0392@1|root,COG0392@2|Bacteria,2GP8H@201174|Actinobacteria,4FGD9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158463_k127_4207455_3	644283.Micau_3613	1.994e-86	303.0	COG0438@1|root,COG0438@2|Bacteria,2GYA2@201174|Actinobacteria,4DA0W@85008|Micromonosporales	201174|Actinobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_4207455_8	1245475.ANAE01000087_gene1149	6.274e-52	186.0	COG0720@1|root,COG0720@2|Bacteria,2II5D@201174|Actinobacteria,4EPDI@85012|Streptosporangiales	201174|Actinobacteria	H	6-pyruvoyl tetrahydropterin synthase	ptpS	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158463_k127_4207455_1	1298863.AUEP01000004_gene1937	1.848e-139	452.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4DSG4@85009|Propionibacteriales	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
SRR25158463_k127_4207455_7	1150864.MILUP08_44100	1.802e-58	217.0	COG0558@1|root,COG0558@2|Bacteria,2GIST@201174|Actinobacteria,4DDWB@85008|Micromonosporales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
SRR25158463_k127_4207455_11	55952.BU52_27640	1.476e-22	112.0	COG1368@1|root,COG1368@2|Bacteria,2GKS9@201174|Actinobacteria	201174|Actinobacteria	M	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158463_k127_4210812_4	1380370.JIBA01000004_gene2282	5.712e-09	57.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4FEBI@85021|Intrasporangiaceae	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158463_k127_4210812_3	710696.Intca_2910	6.92e-59	216.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4FGNB@85021|Intrasporangiaceae	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158463_k127_4210812_1	1386089.N865_20130	2.876e-156	499.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4FEKZ@85021|Intrasporangiaceae	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	malR	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
SRR25158463_k127_4210812_0	710696.Intca_2916	1.315e-194	619.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4FF7N@85021|Intrasporangiaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158463_k127_4210812_2	367299.JOEE01000006_gene715	6.472e-156	496.0	COG3642@1|root,COG3642@2|Bacteria,2GIX0@201174|Actinobacteria,4FE9W@85021|Intrasporangiaceae	201174|Actinobacteria	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158463_k127_4214576_8	469383.Cwoe_3717	9.565e-68	246.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158463_k127_4214576_6	1380390.JIAT01000010_gene4436	1.838e-130	436.0	COG2203@1|root,COG3852@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4585@2|Bacteria,2H306@201174|Actinobacteria	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HisKA_3,PAS_9
SRR25158463_k127_4214576_4	1223545.GS4_05_02810	3.938e-171	547.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4GB0D@85026|Gordoniaceae	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3,1.13.12.4	ko:K00101,ko:K00467	ko00620,ko01100,map00620,map01100	-	R00196,R00319	RC00044,RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158463_k127_4214576_1	1380370.JIBA01000019_gene1004	1.051e-207	656.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FEWD@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_4214576_3	1172185.KB911516_gene2537	2.261e-183	589.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4FVHE@85025|Nocardiaceae	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158463_k127_4214576_2	1380356.JNIK01000013_gene4345	2.029e-198	623.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4EUI8@85013|Frankiales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158463_k127_4214576_0	710696.Intca_0705	5.879e-312	999.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,2GJ5U@201174|Actinobacteria,4FFM6@85021|Intrasporangiaceae	201174|Actinobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
SRR25158463_k127_4214576_5	710696.Intca_0704	5.176e-146	495.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4FEVN@85021|Intrasporangiaceae	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
SRR25158463_k127_4214576_7	1120948.KB903229_gene5058	9.925e-80	270.0	COG1881@1|root,COG1881@2|Bacteria,2GMIG@201174|Actinobacteria,4DYXA@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family	ybhB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SRR25158463_k127_4254797_0	1043205.AFYF01000056_gene2595	8.404e-265	819.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4FFFF@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158463_k127_4254797_3	1193181.BN10_680030	5.908e-103	358.0	COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria,4FGTM@85021|Intrasporangiaceae	201174|Actinobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
SRR25158463_k127_4254797_2	1193181.BN10_680029	5.513e-119	398.0	COG2307@1|root,COG2307@2|Bacteria,2GN0T@201174|Actinobacteria,4FGK6@85021|Intrasporangiaceae	201174|Actinobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
SRR25158463_k127_4254797_1	1193181.BN10_680028	4.81e-136	438.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4FF5D@85021|Intrasporangiaceae	201174|Actinobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2
SRR25158463_k127_444901_10	367299.JOEE01000001_gene1479	7.468e-60	211.0	COG0266@1|root,COG0266@2|Bacteria,2GKUI@201174|Actinobacteria,4FG79@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the FPG family	nei1	GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K05522,ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158463_k127_444901_7	1385518.N798_12985	9.339e-117	384.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4FEKJ@85021|Intrasporangiaceae	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158463_k127_444901_11	1151119.KB895490_gene2030	6.069e-57	206.0	COG1309@1|root,COG1309@2|Bacteria,2IR68@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_444901_2	1385520.N802_06945	6.797e-163	531.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4FHS3@85021|Intrasporangiaceae	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158463_k127_444901_3	471853.Bcav_4085	1.989e-145	474.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158463_k127_444901_12	1304865.JAGF01000001_gene1494	9.621e-42	156.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria	201174|Actinobacteria	S	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158463_k127_444901_9	570268.ANBB01000088_gene173	8.385e-81	275.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4EJAH@85012|Streptosporangiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158463_k127_444901_4	1172188.KB911826_gene83	1.136e-123	415.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4FEWY@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158463_k127_444901_6	1385519.N801_07095	7.214e-118	386.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4FF44@85021|Intrasporangiaceae	201174|Actinobacteria	L	DNA ligase	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158463_k127_444901_13	1184607.AUCHE_03_01650	1.143e-40	153.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,4F74G@85018|Dermatophilaceae	201174|Actinobacteria	S	Lsr2	lsr	-	-	-	-	-	-	-	-	-	-	-	Lsr2
SRR25158463_k127_444901_14	313589.JNB_13763	9.921e-14	79.0	2DD1H@1|root,2ZG5F@2|Bacteria,2I0PI@201174|Actinobacteria,4FHZX@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_444901_0	1385518.N798_12940	2.826e-258	804.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0008150,GO:0040007	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158463_k127_444901_5	1193181.BN10_1210020	1.568e-118	389.0	COG0029@1|root,COG0157@1|root,COG0029@2|Bacteria,COG0157@2|Bacteria,2I2IJ@201174|Actinobacteria,4FE43@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158463_k127_444901_1	1172188.KB911826_gene98	8.237e-251	800.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4FE43@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158463_k127_444901_8	1380370.JIBA01000019_gene1104	2.245e-95	321.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria,4FE81@85021|Intrasporangiaceae	201174|Actinobacteria	S	Coenzyme F420-dependent NADP oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158463_k127_455589_0	570268.ANBB01000015_gene3708	3.585e-203	640.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4EHMU@85012|Streptosporangiales	201174|Actinobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158463_k127_455589_3	1223543.GP2_016_00120	1.056e-56	209.0	COG0596@1|root,COG0596@2|Bacteria,2IAVM@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158463_k127_455589_2	935866.JAER01000031_gene1383	9.311e-108	355.0	COG1414@1|root,COG1414@2|Bacteria,2GJUA@201174|Actinobacteria,4DNQB@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	iclR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158463_k127_455589_1	710696.Intca_2854	2.158e-108	355.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4FEA3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Malate dehydrogenase	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158463_k127_470886_5	1380370.JIBA01000001_gene2214	1.053e-103	342.0	COG3409@1|root,COG3409@2|Bacteria,2IDIJ@201174|Actinobacteria,4FF8V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
SRR25158463_k127_470886_4	1380370.JIBA01000001_gene2215	2.168e-114	384.0	COG0365@1|root,COG0365@2|Bacteria,2I2IW@201174|Actinobacteria,4FGQ9@85021|Intrasporangiaceae	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158463_k127_470886_1	1380370.JIBA01000001_gene2216	1.69e-198	625.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4FEU8@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158463_k127_470886_6	1386089.N865_17610	3.979e-46	179.0	COG2456@1|root,COG2456@2|Bacteria,2GQTD@201174|Actinobacteria,4FH2H@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
SRR25158463_k127_470886_3	1172188.KB911824_gene3186	3.127e-126	406.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4FEXS@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158463_k127_470886_0	1172188.KB911824_gene3187	0.0	1045.0	COG0438@1|root,COG0438@2|Bacteria,2GX8V@201174|Actinobacteria,4FE76@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158463_k127_470886_2	1172188.KB911824_gene3188	8.898e-156	497.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4FE40@85021|Intrasporangiaceae	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	Glycos_transf_2,LPG_synthase_TM
SRR25158463_k127_470886_7	1385519.N801_02625	3.933e-21	93.0	COG1846@1|root,COG1846@2|Bacteria,2I3KG@201174|Actinobacteria,4FGP7@85021|Intrasporangiaceae	201174|Actinobacteria	K	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,MarR
SRR25158463_k127_489862_3	1385519.N801_13495	2.73e-74	274.0	COG1118@1|root,COG1118@2|Bacteria,2I3KJ@201174|Actinobacteria,4FEFY@85021|Intrasporangiaceae	201174|Actinobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE,TOBE_3
SRR25158463_k127_489862_1	1127134.NOCYR_1470	2.886e-135	434.0	COG4208@1|root,COG4208@2|Bacteria,2GMTK@201174|Actinobacteria,4FXDI@85025|Nocardiaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158463_k127_489862_2	685727.REQ_29480	7.415e-116	384.0	COG0555@1|root,COG0555@2|Bacteria,2GP6P@201174|Actinobacteria,4FVI1@85025|Nocardiaceae	201174|Actinobacteria	O	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SRR25158463_k127_489862_0	1172188.KB911826_gene194	8.513e-162	516.0	COG1613@1|root,COG1613@2|Bacteria,2GJIK@201174|Actinobacteria,4FFZT@85021|Intrasporangiaceae	201174|Actinobacteria	P	sulfate ABC transporter	subI	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SRR25158463_k127_489862_4	479435.Kfla_3930	3.964e-40	153.0	COG1846@1|root,COG1846@2|Bacteria,2GSAM@201174|Actinobacteria,4DSJ3@85009|Propionibacteriales	201174|Actinobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
SRR25158463_k127_506143_1	710696.Intca_0263	4.616e-187	600.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4FFHN@85021|Intrasporangiaceae	201174|Actinobacteria	P	Cytochrome C oxidase assembly protein	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158463_k127_506143_4	1394178.AWOO02000035_gene9014	3.06e-40	153.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4EPR8@85012|Streptosporangiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158463_k127_506143_2	1123024.AUII01000015_gene3750	2.781e-127	428.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DXC9@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
SRR25158463_k127_506143_3	1172188.KB911822_gene1070	1.556e-111	375.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4FE90@85021|Intrasporangiaceae	201174|Actinobacteria	S	apolipoprotein N-acyltransferase	mtnU	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158463_k127_506143_0	710696.Intca_0266	2.246e-271	856.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2GKDT@201174|Actinobacteria,4FFBV@85021|Intrasporangiaceae	201174|Actinobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,NHL,Thioredoxin_8
SRR25158463_k127_507555_11	1043205.AFYF01000087_gene1203	7.073e-17	80.0	COG0346@1|root,COG0346@2|Bacteria,2IMDZ@201174|Actinobacteria,4FGK5@85021|Intrasporangiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158463_k127_507555_6	1184609.KILIM_095_00090	2.627e-45	177.0	2FEQY@1|root,346Q4@2|Bacteria,2GSR9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_507555_2	1380386.JIAW01000002_gene5577	5.586e-153	505.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,235FX@1762|Mycobacteriaceae	201174|Actinobacteria	S	Hydrolase	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158463_k127_507555_10	1068978.AMETH_0786	3.029e-17	95.0	COG2905@1|root,COG2905@2|Bacteria,2GQMA@201174|Actinobacteria,4E6F8@85010|Pseudonocardiales	201174|Actinobacteria	T	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158463_k127_507555_3	710696.Intca_2195	3.615e-123	398.0	COG0289@1|root,COG1670@1|root,COG0289@2|Bacteria,COG1670@2|Bacteria,2GM2T@201174|Actinobacteria,4FFTT@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158463_k127_507555_9	1380370.JIBA01000010_gene2404	3.002e-28	128.0	2B5PK@1|root,31YJ2@2|Bacteria,2H0V7@201174|Actinobacteria,4FJQ3@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_507555_1	1380370.JIBA01000010_gene2403	0.0	1169.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4FK2T@85021|Intrasporangiaceae	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
SRR25158463_k127_507555_4	1380370.JIBA01000010_gene2402	4.842e-84	284.0	COG3945@1|root,COG3945@2|Bacteria,2IKF0@201174|Actinobacteria,4FGYI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158463_k127_507555_5	1306174.JODP01000009_gene6321	8.117e-55	199.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria	201174|Actinobacteria	C	PFAM MOSC domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158463_k127_507555_8	1184609.KILIM_020_00040	4.577e-35	147.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4F838@85018|Dermatophilaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_507555_0	1386089.N865_17455	0.0	1313.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4FER2@85021|Intrasporangiaceae	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158463_k127_507555_7	710696.Intca_2197	9.941e-44	161.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4FHIT@85021|Intrasporangiaceae	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158463_k127_507555_12	1122622.ATWJ01000007_gene1940	1.774e-14	74.0	COG2852@1|root,COG2852@2|Bacteria,2GNZQ@201174|Actinobacteria,4FG2I@85021|Intrasporangiaceae	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
SRR25158463_k127_511321_2	1386089.N865_10000	1.558e-173	550.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FESA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158463_k127_511321_1	526225.Gobs_1743	4.976e-194	608.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4ES8V@85013|Frankiales	201174|Actinobacteria	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158463_k127_511321_3	1172188.KB911821_gene1470	1.413e-159	516.0	COG1403@1|root,COG1403@2|Bacteria,2I9AH@201174|Actinobacteria,4FG65@85021|Intrasporangiaceae	201174|Actinobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158463_k127_511321_0	1122138.AQUZ01000015_gene6783	1.186e-227	717.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,4DNUN@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158463_k127_511321_6	1032480.MLP_05210	2.768e-44	167.0	COG4319@1|root,COG4319@2|Bacteria,2IPWP@201174|Actinobacteria,4DVAD@85009|Propionibacteriales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
SRR25158463_k127_511321_5	1385520.N802_11095	2.516e-98	326.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158463_k127_511321_4	367299.JOEE01000004_gene1207	1.71e-108	352.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FFRV@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158463_k127_5133_0	1449346.JQMO01000003_gene3940	0.0	1062.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,2M2AK@2063|Kitasatospora	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
SRR25158463_k127_5133_1	1120934.KB894434_gene4600	6.939e-136	446.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DYGS@85010|Pseudonocardiales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158463_k127_5133_3	710685.MycrhN_5356	6.627e-63	224.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,233TP@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
SRR25158463_k127_5133_5	446468.Ndas_2825	1.508e-37	160.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria,4EIWQ@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158463_k127_5133_6	1448860.BBJO01000007_gene1615	4.217e-19	97.0	COG1183@1|root,arCOG00671@2157|Archaea,2XT0G@28890|Euryarchaeota,23TMI@183963|Halobacteria	183963|Halobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158463_k127_5133_2	1380370.JIBA01000011_gene3061	5.307e-90	319.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158463_k127_5133_4	1123024.AUII01000002_gene1153	3.248e-53	205.0	COG0477@1|root,COG0477@2|Bacteria,2IP3M@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_5339_7	1193181.BN10_1420002	1.289e-42	158.0	COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4FEYK@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC transporter (Permease)	ykoE	-	-	ko:K16925	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.30	-	-	ABC_cobalt
SRR25158463_k127_5339_0	1380370.JIBA01000012_gene3740	9.116e-252	801.0	COG0619@1|root,COG1122@1|root,COG0619@2|Bacteria,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4FESH@85021|Intrasporangiaceae	201174|Actinobacteria	P	ABC transporter, ATP-binding protein	ykoD	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ
SRR25158463_k127_5339_4	1121017.AUFG01000015_gene2687	2.229e-60	214.0	COG0406@1|root,COG0406@2|Bacteria,2GP71@201174|Actinobacteria,4FGYW@85021|Intrasporangiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	lpqD	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158463_k127_5339_3	479433.Caci_3342	1.299e-100	331.0	COG2249@1|root,COG2249@2|Bacteria	2|Bacteria	K	NAD(P)H dehydrogenase (quinone) activity	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
SRR25158463_k127_5339_5	479433.Caci_3341	1.519e-47	185.0	COG1846@1|root,COG1846@2|Bacteria,2HB1T@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158463_k127_5339_6	710685.MycrhN_4364	5.564e-44	164.0	COG1846@1|root,COG1846@2|Bacteria,2IH8B@201174|Actinobacteria,238ZY@1762|Mycobacteriaceae	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_5339_1	710685.MycrhN_4363	2.764e-195	624.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,233MX@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	yfmO	-	-	ko:K08221	-	-	-	-	ko00000,ko02000	2.A.1.32	-	-	MFS_1
SRR25158463_k127_5339_2	313589.JNB_10859	5.84e-124	399.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4FFAU@85021|Intrasporangiaceae	201174|Actinobacteria	E	in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor	aspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	iNJ661.Rv0337c	Aminotran_1_2
SRR25158463_k127_571160_5	1172188.KB911821_gene1448	5.959e-34	131.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4FEUY@85021|Intrasporangiaceae	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158463_k127_571160_2	1386089.N865_17925	4.802e-38	151.0	2CQFE@1|root,32SM3@2|Bacteria,2IR42@201174|Actinobacteria,4FH43@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3515)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3515
SRR25158463_k127_571160_4	1380370.JIBA01000014_gene1938	5.796e-34	131.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4FHC8@85021|Intrasporangiaceae	201174|Actinobacteria	K	AsnC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158463_k127_571160_1	1121385.AQXW01000003_gene445	2.508e-102	342.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,1ZW0D@145357|Dermacoccaceae	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR25158463_k127_571160_6	1380370.JIBA01000014_gene1936	1.333e-32	132.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4FHCB@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158463_k127_571160_0	1386089.N865_17900	3.495e-163	531.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4FFN9@85021|Intrasporangiaceae	201174|Actinobacteria	S	Dihydroxyacetone kinase	dak3	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158463_k127_571160_3	710696.Intca_2316	5.347e-37	144.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4FE3F@85021|Intrasporangiaceae	201174|Actinobacteria	L	ATP-dependent DNA helicase RecG	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158463_k127_575363_1	710696.Intca_2877	2.497e-181	574.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FFS6@85021|Intrasporangiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_575363_11	1380370.JIBA01000010_gene2495	2.766e-22	104.0	COG4086@1|root,COG4086@2|Bacteria,2GTEN@201174|Actinobacteria,4FHY0@85021|Intrasporangiaceae	201174|Actinobacteria	S	MT0933-like antitoxin protein	-	-	-	-	-	-	-	-	-	-	-	-	MT0933_antitox
SRR25158463_k127_575363_7	1032480.MLP_00800	4.866e-89	308.0	COG0789@1|root,COG2764@1|root,COG0789@2|Bacteria,COG2764@2|Bacteria,2HZYN@201174|Actinobacteria,4DUKV@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,MerR_1
SRR25158463_k127_575363_10	1032480.MLP_00810	2.83e-44	166.0	COG2764@1|root,COG2764@2|Bacteria,2GMZD@201174|Actinobacteria,4DS7K@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158463_k127_575363_3	1380370.JIBA01000019_gene1097	9.354e-147	475.0	COG0666@1|root,COG0666@2|Bacteria,2GIUA@201174|Actinobacteria,4FIU1@85021|Intrasporangiaceae	201174|Actinobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
SRR25158463_k127_575363_8	1035308.AQYY01000001_gene2765	3.895e-80	278.0	COG2343@1|root,COG2343@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF427)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,NTP_transf_9
SRR25158463_k127_575363_0	1172188.KB911822_gene704	3.597e-260	810.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria,4FE9K@85021|Intrasporangiaceae	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
SRR25158463_k127_575363_2	1078020.KEK_02931	1.757e-178	566.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,2336I@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_575363_5	1172188.KB911821_gene2050	2.714e-102	362.0	COG2755@1|root,COG2755@2|Bacteria,2GNBP@201174|Actinobacteria,4FFST@85021|Intrasporangiaceae	201174|Actinobacteria	E	G-D-S-L family lipolytic protein	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158463_k127_575363_4	1172188.KB911821_gene2049	6.419e-105	350.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4FEUP@85021|Intrasporangiaceae	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158463_k127_575363_6	1095767.CAHD01000040_gene1482	1.204e-89	304.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria	201174|Actinobacteria	K	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158463_k127_575363_9	1386089.N865_04310	4.733e-78	266.0	COG0546@1|root,COG0546@2|Bacteria,2I9FC@201174|Actinobacteria,4FGUD@85021|Intrasporangiaceae	201174|Actinobacteria	S	HAD family hydrolase	-	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158463_k127_575363_12	1408433.JHXV01000009_gene1268	1.801e-18	98.0	COG1233@1|root,COG1233@2|Bacteria,4NJEE@976|Bacteroidetes,1I0GA@117743|Flavobacteriia	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_1
SRR25158463_k127_614753_3	367299.JOEE01000002_gene2619	4.512e-22	109.0	2EIMR@1|root,33CD0@2|Bacteria,2I62F@201174|Actinobacteria,4FJZH@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_614753_1	367299.JOEE01000002_gene2618	3.721e-89	297.0	COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4FFQH@85021|Intrasporangiaceae	201174|Actinobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158463_k127_614753_0	1386089.N865_16015	2.041e-100	335.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4FE73@85021|Intrasporangiaceae	201174|Actinobacteria	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158463_k127_614753_2	1385518.N798_06980	8.683e-23	105.0	COG5340@1|root,COG5340@2|Bacteria,2ICBY@201174|Actinobacteria,4FHI9@85021|Intrasporangiaceae	201174|Actinobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
SRR25158463_k127_636240_8	1386089.N865_09255	4.814e-27	114.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,4FH5E@85021|Intrasporangiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	litS	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158463_k127_636240_7	935839.JAGJ01000009_gene562	6.55e-33	136.0	COG3764@1|root,COG3764@2|Bacteria,2IR30@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158463_k127_636240_2	1386089.N865_09245	5.166e-93	312.0	arCOG06227@1|root,2ZCRG@2|Bacteria,2I96P@201174|Actinobacteria,4FE9G@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158463_k127_636240_0	56110.Oscil6304_3386	2.134e-146	493.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	2|Bacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	hstK	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,GGDEF,Guanylate_cyc,HATPase_c,HisKA,PAS_9,Pkinase,Response_reg,SpoIIE
SRR25158463_k127_636240_6	1121459.AQXE01000002_gene1216	1.851e-44	166.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,42W97@68525|delta/epsilon subdivisions,2WS2D@28221|Deltaproteobacteria,2MCB2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158463_k127_636240_11	197221.22296102	0.0001025	54.0	COG2202@1|root,COG5000@1|root,COG2202@2|Bacteria,COG5000@2|Bacteria,1G1U7@1117|Cyanobacteria	1117|Cyanobacteria	T	PAS PAC sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,PAS_3,PAS_4,PAS_9,dCache_1
SRR25158463_k127_636240_3	929712.KI912613_gene249	6.889e-90	331.0	COG0814@1|root,COG0814@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	Trp_Tyr_perm
SRR25158463_k127_636240_4	765420.OSCT_2174	5.283e-85	295.0	COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia	32061|Chloroflexia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRR25158463_k127_636240_9	263358.VAB18032_00075	1.652e-22	109.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4D9KA@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158463_k127_636240_1	1386089.N865_19490	5.793e-138	452.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FEIG@85021|Intrasporangiaceae	201174|Actinobacteria	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158463_k127_636240_5	1121017.AUFG01000001_gene2984	9.358e-85	290.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria,4FJ0E@85021|Intrasporangiaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158463_k127_636240_10	367299.JOEE01000008_gene363	3.463e-17	89.0	2EN8E@1|root,33FW7@2|Bacteria,2GSD4@201174|Actinobacteria,4FHSP@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_637601_7	981369.JQMJ01000004_gene610	6.951e-09	56.0	COG4994@1|root,COG4994@2|Bacteria,2IRDD@201174|Actinobacteria,2NJ88@228398|Streptacidiphilus	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158463_k127_637601_3	1385519.N801_07000	2.065e-88	298.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4FFCH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SRR25158463_k127_637601_1	1449048.JQKU01000003_gene1744	1.562e-125	406.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,234X4@1762|Mycobacteriaceae	201174|Actinobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158463_k127_637601_4	369723.Strop_2107	1.956e-57	214.0	2CFWP@1|root,33X27@2|Bacteria,2IBG6@201174|Actinobacteria,4DAXP@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_637601_0	1150864.MILUP08_43732	5.54e-207	655.0	COG0367@1|root,COG0367@2|Bacteria,2I9UP@201174|Actinobacteria,4D9YF@85008|Micromonosporales	201174|Actinobacteria	E	Glutamine amidotransferase domain	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158463_k127_637601_2	105420.BBPO01000045_gene1083	4.214e-96	336.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,2NEHB@228398|Streptacidiphilus	201174|Actinobacteria	V	FemAB family	femX	-	2.3.2.10	ko:K05363	ko00550,ko01100,map00550,map01100	-	R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
SRR25158463_k127_649339_13	944560.HMPREF9058_0421	1.245e-17	85.0	COG2378@1|root,COG2378@2|Bacteria,2HKWR@201174|Actinobacteria,4D5XX@85005|Actinomycetales	201174|Actinobacteria	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11
SRR25158463_k127_649339_11	944560.HMPREF9058_0420	5.078e-39	153.0	2A1F3@1|root,30PND@2|Bacteria,2HKUE@201174|Actinobacteria,4D5TQ@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_649339_5	136273.GY22_01985	3.113e-81	280.0	COG3153@1|root,COG3153@2|Bacteria,2I58Y@201174|Actinobacteria	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_649339_12	1120934.KB894413_gene3408	4.401e-38	149.0	2DWTW@1|root,341UU@2|Bacteria,2GPSK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_649339_6	1048339.KB913029_gene2083	1.132e-69	243.0	COG3764@1|root,COG3764@2|Bacteria,2I8KF@201174|Actinobacteria	201174|Actinobacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158463_k127_649339_8	1386089.N865_08100	1.876e-58	213.0	COG1503@1|root,COG1503@2|Bacteria,2IFQH@201174|Actinobacteria,4FGXH@85021|Intrasporangiaceae	201174|Actinobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_649339_9	1385520.N802_17475	5.057e-57	199.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4FGZ7@85021|Intrasporangiaceae	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158463_k127_649339_7	1121385.AQXW01000004_gene1212	4.66e-62	230.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,1ZVZF@145357|Dermacoccaceae	201174|Actinobacteria	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158463_k127_649339_1	367299.JOEE01000005_gene3602	5.479e-213	682.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4FETM@85021|Intrasporangiaceae	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158463_k127_649339_3	1380370.JIBA01000013_gene1524	1.628e-139	445.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4FESX@85021|Intrasporangiaceae	201174|Actinobacteria	O	Iron ABC transporter ATP-binding protein	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158463_k127_649339_10	1121017.AUFG01000001_gene3079	7.351e-41	154.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4FGX6@85021|Intrasporangiaceae	201174|Actinobacteria	P	ferredoxin	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158463_k127_649339_2	1123251.ATWM01000002_gene378	7.032e-161	532.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4FF87@85021|Intrasporangiaceae	201174|Actinobacteria	O	ABC transporter (Permease)	sufD	GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158463_k127_649339_0	367299.JOEE01000005_gene3598	7.358e-284	889.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4FEEZ@85021|Intrasporangiaceae	201174|Actinobacteria	O	Fe-S cluster assembly	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158463_k127_649339_4	1172188.KB911823_gene440	5.231e-86	291.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4FGFY@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SRR25158463_k127_659991_5	408672.NBCG_04540	1.343e-77	263.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria,4DNFW@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158463_k127_659991_3	1033730.CAHG01000015_gene765	9.812e-138	447.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4DPME@85009|Propionibacteriales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158463_k127_659991_0	1123258.AQXZ01000013_gene1949	6.675e-216	678.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4FUA0@85025|Nocardiaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158463_k127_659991_4	1122622.ATWJ01000015_gene523	2.225e-79	269.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria,4FFVX@85021|Intrasporangiaceae	201174|Actinobacteria	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_659991_7	1386089.N865_04825	2.57e-34	135.0	2EAZS@1|root,32VK9@2|Bacteria,2I73Y@201174|Actinobacteria,4FHIA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158463_k127_659991_2	1380370.JIBA01000012_gene3542	4.084e-183	604.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4FEQA@85021|Intrasporangiaceae	201174|Actinobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
SRR25158463_k127_659991_1	1386089.N865_18900	8.929e-215	676.0	COG0277@1|root,COG0277@2|Bacteria,2GKQR@201174|Actinobacteria,4FFK9@85021|Intrasporangiaceae	201174|Actinobacteria	C	FAD-linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SRR25158463_k127_659991_6	1172188.KB911826_gene21	2.637e-77	265.0	COG3246@1|root,COG3246@2|Bacteria,2GMMZ@201174|Actinobacteria,4FIIC@85021|Intrasporangiaceae	201174|Actinobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158463_k127_659991_8	266940.Krad_0643	4.225e-30	121.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0008150,GO:0040007	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0553	MR_MLE_C
SRR25158463_k127_686094_7	1386089.N865_13735	1.95e-32	131.0	COG2246@1|root,COG2246@2|Bacteria,2I30T@201174|Actinobacteria,4FH8Q@85021|Intrasporangiaceae	201174|Actinobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
SRR25158463_k127_686094_0	1210046.B277_10234	2.69e-269	863.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,4FFKV@85021|Intrasporangiaceae	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158463_k127_686094_5	1120950.KB892739_gene3977	4.879e-74	263.0	COG3153@1|root,COG3153@2|Bacteria,2I3ZT@201174|Actinobacteria,4DPMJ@85009|Propionibacteriales	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158463_k127_686094_3	1122138.AQUZ01000017_gene6587	3.423e-129	428.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1,MFS_1_like
SRR25158463_k127_686094_1	1380370.JIBA01000012_gene3697	4.736e-163	528.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4FF2V@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158463_k127_686094_2	1385518.N798_02375	2.4e-129	416.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4FFK0@85021|Intrasporangiaceae	201174|Actinobacteria	T	transcriptional regulator	tcrX	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_686094_6	1210046.B277_10254	1.141e-33	132.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4FH9F@85021|Intrasporangiaceae	201174|Actinobacteria	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158463_k127_686094_4	1385518.N798_02345	2.853e-99	325.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4FE6J@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SRR25158463_k127_692679_0	1386089.N865_14120	0.0	1328.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4FG2B@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158463_k127_692679_1	1172188.KB911820_gene2678	5.872e-126	413.0	2C4HC@1|root,2Z9UU@2|Bacteria,2HV69@201174|Actinobacteria,4FHPF@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
SRR25158463_k127_719150_2	258052.JNYV01000005_gene2472	3.595e-48	173.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,2M273@2063|Kitasatospora	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_primase_S
SRR25158463_k127_719150_1	1122609.AUGT01000021_gene1294	8.433e-89	306.0	COG0494@1|root,COG0494@2|Bacteria,2I2DQ@201174|Actinobacteria,4DQ4P@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,NUDIX
SRR25158463_k127_719150_0	1121017.AUFG01000012_gene1791	3.686e-199	626.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4FEQG@85021|Intrasporangiaceae	201174|Actinobacteria	C	ferredoxin oxidoreductase	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158463_k127_725923_2	1172188.KB911820_gene2409	2.067e-132	428.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria,4FEIP@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158463_k127_725923_1	1380370.JIBA01000012_gene3406	7.924e-190	608.0	COG0477@1|root,COG0477@2|Bacteria,2GK8M@201174|Actinobacteria,4FG58@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158463_k127_725923_0	1172188.KB911820_gene2411	1.773e-237	745.0	COG1404@1|root,COG1404@2|Bacteria,2GJ14@201174|Actinobacteria,4FFNV@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_S8
SRR25158463_k127_725923_5	1380370.JIBA01000012_gene3408	2.199e-46	175.0	2B6QB@1|root,31ZP3@2|Bacteria,2H2EG@201174|Actinobacteria,4FIGR@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_725923_3	1386089.N865_19110	2.387e-66	241.0	2BK7Q@1|root,32EMK@2|Bacteria,2GXAI@201174|Actinobacteria,4FHZP@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_725923_4	710696.Intca_3565	1.407e-52	206.0	COG2963@1|root,COG2963@2|Bacteria,2IJ0M@201174|Actinobacteria,4FIH3@85021|Intrasporangiaceae	201174|Actinobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
SRR25158463_k127_725923_6	1386089.N865_19095	1.412e-12	74.0	COG1276@1|root,COG3336@1|root,COG1276@2|Bacteria,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4FFHN@85021|Intrasporangiaceae	201174|Actinobacteria	P	Cytochrome C oxidase assembly protein	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158463_k127_728019_3	367299.JOEE01000003_gene3030	8.454e-64	246.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4FGRU@85021|Intrasporangiaceae	201174|Actinobacteria	H	Biotin protein ligase C terminal domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158463_k127_728019_0	367299.JOEE01000003_gene3031	1.648e-305	940.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4FEHJ@85021|Intrasporangiaceae	201174|Actinobacteria	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	GO:0003674,GO:0003824,GO:0003989,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009317,GO:0009987,GO:0015977,GO:0016020,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0030312,GO:0032787,GO:0032991,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0071944,GO:0072329,GO:1901575,GO:1902494	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158463_k127_728019_6	710696.Intca_1243	3.716e-06	58.0	2B5VM@1|root,31YRH@2|Bacteria,2H0T8@201174|Actinobacteria,4FI6P@85021|Intrasporangiaceae	201174|Actinobacteria	S	Acyl-CoA carboxylase epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACC_epsilon
SRR25158463_k127_728019_4	1298863.AUEP01000003_gene2775	5.136e-25	113.0	COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4DPC9@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158463_k127_728019_5	1122609.AUGT01000021_gene1270	2.583e-07	58.0	COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4DPC9@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158463_k127_728019_2	298655.KI912266_gene1624	5.193e-85	290.0	COG2084@1|root,COG2084@2|Bacteria,2GTGE@201174|Actinobacteria	201174|Actinobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,F420_oxidored,NAD_binding_2
SRR25158463_k127_728019_1	526225.Gobs_4913	5.401e-171	559.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4ERBS@85013|Frankiales	201174|Actinobacteria	S	peptidase U62, modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158463_k127_749117_2	1385519.N801_07175	2.374e-51	187.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4FGD7@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158463_k127_749117_4	1449068.JMLQ01000009_gene3665	1.721e-41	165.0	COG3118@1|root,COG3118@2|Bacteria,2I2FB@201174|Actinobacteria,4G16Y@85025|Nocardiaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	-	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SRR25158463_k127_749117_3	1386089.N865_16585	4.176e-42	162.0	COG2968@1|root,COG2968@2|Bacteria,2HU9D@201174|Actinobacteria,4FF6Z@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
SRR25158463_k127_749117_1	479435.Kfla_4775	3.844e-57	214.0	COG0741@1|root,COG0741@2|Bacteria,2I2XS@201174|Actinobacteria,4DX3A@85009|Propionibacteriales	201174|Actinobacteria	M	Membrane-bound lytic murein transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT_2
SRR25158463_k127_749117_0	367299.JOEE01000003_gene2887	2.605e-89	308.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4FFEI@85021|Intrasporangiaceae	201174|Actinobacteria	L	DEAD DEAH box helicase	rhlE_2	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158463_k127_758935_3	1172188.KB911825_gene3631	8.542e-45	168.0	COG1595@1|root,COG1595@2|Bacteria,2ISVJ@201174|Actinobacteria,4FHEH@85021|Intrasporangiaceae	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
SRR25158463_k127_758935_1	1380370.JIBA01000013_gene1305	1.822e-59	218.0	2B9CE@1|root,322Q4@2|Bacteria,2IKT2@201174|Actinobacteria,4FGMR@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
SRR25158463_k127_758935_2	1386089.N865_18675	4.382e-51	185.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4FGYU@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158463_k127_758935_4	1380370.JIBA01000013_gene1303	4.369e-43	172.0	COG0711@1|root,COG0711@2|Bacteria,2IQQZ@201174|Actinobacteria,4FHI1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_758935_6	1380370.JIBA01000016_gene756	1.697e-29	118.0	2BHZE@1|root,32C3X@2|Bacteria,2GQT8@201174|Actinobacteria,4FHYF@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_758935_5	1386089.N865_03420	6.133e-41	154.0	2EVGU@1|root,33NX7@2|Bacteria,2I855@201174|Actinobacteria,4FK3F@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_758935_0	1386089.N865_03425	1.594e-87	296.0	COG1051@1|root,COG1051@2|Bacteria,2GPP2@201174|Actinobacteria,4FGWP@85021|Intrasporangiaceae	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158463_k127_758935_7	390989.JOEG01000017_gene6182	8.336e-27	111.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria,4DFXK@85008|Micromonosporales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR25158463_k127_779514_0	882082.SaccyDRAFT_2613	4.41e-313	977.0	COG3960@1|root,COG3960@2|Bacteria,2GJY3@201174|Actinobacteria,4DX9N@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the TPP enzyme family	gcl	-	4.1.1.47	ko:K01608	ko00630,ko01100,map00630,map01100	-	R00013	RC00899	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158463_k127_779514_6	882082.SaccyDRAFT_2612	1.086e-126	422.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4E1KD@85010|Pseudonocardiales	201174|Actinobacteria	I	2-hydroxy-3-oxopropionate reductase	garR	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158463_k127_779514_7	1380386.JIAW01000003_gene635	1.084e-124	404.0	COG3622@1|root,COG3622@2|Bacteria,2GKPC@201174|Actinobacteria,232V4@1762|Mycobacteriaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	hyi	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158463_k127_779514_5	1209984.BN978_07260	2.232e-158	503.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria,233RJ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	uox	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRR25158463_k127_779514_8	1370121.AUWS01000025_gene3077	1.646e-39	149.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,23AVN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158463_k127_779514_3	1121385.AQXW01000004_gene2506	2.41e-184	604.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,1ZVM9@145357|Dermacoccaceae	201174|Actinobacteria	F	Permease family	pbuX2	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
SRR25158463_k127_779514_4	882082.SaccyDRAFT_2604	9.153e-167	556.0	COG2301@1|root,COG2301@2|Bacteria,2GNNK@201174|Actinobacteria,4E0B4@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
SRR25158463_k127_779514_1	935866.JAER01000031_gene1385	5.202e-264	833.0	COG2225@1|root,COG2225@2|Bacteria,2GJGP@201174|Actinobacteria,4DNPW@85009|Propionibacteriales	201174|Actinobacteria	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158463_k127_779514_2	196162.Noca_2034	1.26e-200	631.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4DNVT@85009|Propionibacteriales	201174|Actinobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158463_k127_790946_7	313589.JNB_09294	4.163e-49	179.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4FF0I@85021|Intrasporangiaceae	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158463_k127_790946_3	1385519.N801_04730	5.923e-132	441.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4FF7M@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158463_k127_790946_2	1380370.JIBA01000019_gene1050	5.943e-134	439.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4FE32@85021|Intrasporangiaceae	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
SRR25158463_k127_790946_0	1193181.BN10_240004	3.28e-218	689.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4FF2G@85021|Intrasporangiaceae	201174|Actinobacteria	H	Uroporphyrin-III C-methyltransferase	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158463_k127_790946_1	710696.Intca_0661	1.091e-147	477.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4FEW1@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158463_k127_790946_9	1121926.AXWO01000004_gene1012	3.747e-13	81.0	2AX6H@1|root,31P55@2|Bacteria,2GZ2I@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_790946_5	1133849.O3I_013995	9.522e-59	212.0	COG0500@1|root,COG0500@2|Bacteria,2HJH6@201174|Actinobacteria,4G6SI@85025|Nocardiaceae	201174|Actinobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
SRR25158463_k127_790946_8	1194972.MVAC_03731	3.615e-13	72.0	COG3740@1|root,COG3740@2|Bacteria,2II2M@201174|Actinobacteria,239DQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phage prohead protease, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_790946_10	44454.NF84_01645	1.056e-07	61.0	COG3740@1|root,COG3740@2|Bacteria,2II2M@201174|Actinobacteria,239DQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phage prohead protease, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_790946_6	188626.HMPREF0321_2473	2.191e-50	186.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,1ZWX9@145357|Dermacoccaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158463_k127_790946_4	1386089.N865_19870	1.147e-78	269.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4FF4C@85021|Intrasporangiaceae	201174|Actinobacteria	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158463_k127_7912_6	266940.Krad_0667	7.445e-33	129.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria	201174|Actinobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158463_k127_7912_8	1386089.N865_03500	9.527e-14	81.0	2C4M0@1|root,3016Q@2|Bacteria,2INCQ@201174|Actinobacteria,4FGYB@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_7912_1	1172188.KB911821_gene1941	1.973e-157	504.0	COG1816@1|root,COG1816@2|Bacteria,2GKJP@201174|Actinobacteria,4FEG3@85021|Intrasporangiaceae	201174|Actinobacteria	F	adenosine deaminase	add	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158463_k127_7912_5	1172188.KB911821_gene1940	8.06e-38	164.0	2E6NT@1|root,32UXC@2|Bacteria,2I895@201174|Actinobacteria,4FGRH@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_7912_0	1172188.KB911821_gene1939	9.739e-218	683.0	COG1167@1|root,COG1167@2|Bacteria,2GKVK@201174|Actinobacteria,4FF5H@85021|Intrasporangiaceae	201174|Actinobacteria	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	aspT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
SRR25158463_k127_7912_7	1385518.N798_05760	7.224e-20	93.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4FHHX@85021|Intrasporangiaceae	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158463_k127_7912_2	1172188.KB911821_gene1937	7.087e-103	347.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4FF79@85021|Intrasporangiaceae	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158463_k127_7912_4	1121017.AUFG01000012_gene1782	1.576e-77	261.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4FGDC@85021|Intrasporangiaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158463_k127_7912_3	1121017.AUFG01000012_gene1781	4.483e-93	320.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4FEH9@85021|Intrasporangiaceae	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158463_k127_794273_1	367299.JOEE01000003_gene2783	6.096e-255	797.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4FFVB@85021|Intrasporangiaceae	201174|Actinobacteria	G	alpha-glucosidase	aglA	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158463_k127_794273_12	1121017.AUFG01000017_gene2513	1.088e-58	205.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4FGWI@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158463_k127_794273_8	1121924.ATWH01000034_gene204	7.165e-86	321.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4FMKH@85023|Microbacteriaceae	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158463_k127_794273_9	1172188.KB911824_gene3294	3.731e-82	287.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4FF0H@85021|Intrasporangiaceae	201174|Actinobacteria	M	mechanosensitive ion channel protein MscS	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158463_k127_794273_0	1386089.N865_15485	0.0	1035.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4FE8H@85021|Intrasporangiaceae	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158463_k127_794273_6	1172188.KB911824_gene3296	3.763e-99	326.0	COG2761@1|root,COG2761@2|Bacteria,2GJNX@201174|Actinobacteria,4FEFH@85021|Intrasporangiaceae	201174|Actinobacteria	Q	DSBA oxidoreductase	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158463_k127_794273_11	1386089.N865_15490	3.498e-63	220.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,4FGPP@85021|Intrasporangiaceae	201174|Actinobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158463_k127_794273_7	1380370.JIBA01000002_gene2676	1.446e-96	328.0	COG2208@1|root,COG2208@2|Bacteria,2GNS3@201174|Actinobacteria,4FECV@85021|Intrasporangiaceae	201174|Actinobacteria	KT	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158463_k127_794273_14	1386089.N865_15500	3.214e-21	102.0	2EJAX@1|root,33D21@2|Bacteria,2HUZD@201174|Actinobacteria,4FJN3@85021|Intrasporangiaceae	201174|Actinobacteria	S	MT0933-like antitoxin protein	-	-	-	-	-	-	-	-	-	-	-	-	MT0933_antitox
SRR25158463_k127_794273_10	1172188.KB911824_gene3299	2.316e-79	271.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4FF0U@85021|Intrasporangiaceae	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
SRR25158463_k127_794273_16	953739.SVEN_2405	3.248e-07	52.0	2C821@1|root,3019I@2|Bacteria,2HD9F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_794273_13	1385518.N798_08635	1.987e-26	115.0	2EVKB@1|root,33P0F@2|Bacteria,2GWBJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_794273_2	1385521.N803_01305	8.513e-195	624.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4FF93@85021|Intrasporangiaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158463_k127_794273_15	1121946.AUAX01000003_gene1833	3.033e-13	84.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_794273_5	1193181.BN10_940010	4.561e-106	349.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4FEPP@85021|Intrasporangiaceae	201174|Actinobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP1	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158463_k127_794273_4	1184607.AUCHE_05_02930	3.68e-107	361.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4F6KW@85018|Dermatophilaceae	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158463_k127_794273_3	1380370.JIBA01000017_gene3001	5.715e-110	357.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4FE7Q@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158463_k127_803582_4	1386089.N865_09610	5.31e-106	353.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4FF2H@85021|Intrasporangiaceae	201174|Actinobacteria	H	molybdopterin	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158463_k127_803582_2	1385519.N801_03130	4.03e-174	559.0	COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4FEYE@85021|Intrasporangiaceae	201174|Actinobacteria	G	UTP--glucose-1-phosphate uridylyltransferase	ugpA	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
SRR25158463_k127_803582_5	1385519.N801_03135	9.114e-29	135.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4FH14@85021|Intrasporangiaceae	201174|Actinobacteria	H	5-formyltetrahydrofolate cyclo-ligase	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SRR25158463_k127_803582_0	1172188.KB911825_gene3794	0.0	1059.0	COG2366@1|root,COG2366@2|Bacteria,2GISQ@201174|Actinobacteria,4FER7@85021|Intrasporangiaceae	201174|Actinobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158463_k127_803582_1	1380370.JIBA01000016_gene927	1.723e-211	667.0	COG3263@1|root,COG3263@2|Bacteria,2GJ9B@201174|Actinobacteria,4FFKQ@85021|Intrasporangiaceae	201174|Actinobacteria	P	Potassium transporter CPA	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
SRR25158463_k127_803582_6	273677.BW34_02018	4.14e-26	113.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4FQ5K@85023|Microbacteriaceae	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158463_k127_803582_3	1172188.KB911825_gene3797	1.663e-127	413.0	COG0005@1|root,COG0005@2|Bacteria,2GKGG@201174|Actinobacteria,4FFIJ@85021|Intrasporangiaceae	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158463_k127_829183_3	66377.JOBH01000004_gene3662	1.658e-66	231.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158463_k127_829183_0	1380356.JNIK01000017_gene3002	3.829e-198	627.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4ES4Y@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158463_k127_829183_1	1385519.N801_07960	9.502e-194	617.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4FEE1@85021|Intrasporangiaceae	201174|Actinobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158463_k127_829183_2	1380370.JIBA01000014_gene2155	2.318e-162	542.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria,4FEX7@85021|Intrasporangiaceae	201174|Actinobacteria	S	protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158463_k127_844489_6	1172188.KB911826_gene37	2.699e-99	326.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4FG3C@85021|Intrasporangiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158463_k127_844489_5	1172188.KB911826_gene36	2.386e-107	360.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4FG0N@85021|Intrasporangiaceae	201174|Actinobacteria	CO	Thiol disulfide interchange protein	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158463_k127_844489_7	313589.JNB_00930	5.703e-72	256.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4FF34@85021|Intrasporangiaceae	201174|Actinobacteria	O	cytochrome c biogenesis protein	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158463_k127_844489_0	1172188.KB911826_gene34	3.593e-288	908.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4FE3H@85021|Intrasporangiaceae	201174|Actinobacteria	O	cytochrome C	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158463_k127_844489_2	1172188.KB911826_gene33	1.112e-176	560.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4FEHY@85021|Intrasporangiaceae	201174|Actinobacteria	O	cytochrome c biogenesis	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158463_k127_844489_9	1386089.N865_19905	7.846e-27	119.0	2EHXC@1|root,33BNY@2|Bacteria,2GQ0C@201174|Actinobacteria,4FHJK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4229)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4229
SRR25158463_k127_844489_1	1386089.N865_19910	5.075e-182	579.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4FFFI@85021|Intrasporangiaceae	201174|Actinobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158463_k127_844489_4	1172188.KB911826_gene30	3.927e-150	481.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4FF0S@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158463_k127_844489_8	1172188.KB911826_gene29	1.874e-35	144.0	2EGDD@1|root,33A58@2|Bacteria,2GR3X@201174|Actinobacteria,4FHNU@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRR25158463_k127_844489_3	1172188.KB911826_gene28	1.013e-165	526.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4FF7B@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_888564_9	710696.Intca_0832	9.922e-66	227.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4FGGQ@85021|Intrasporangiaceae	201174|Actinobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158463_k127_888564_10	1122609.AUGT01000003_gene2287	5.432e-62	218.0	COG2128@1|root,COG2128@2|Bacteria,2HSVU@201174|Actinobacteria,4DWTM@85009|Propionibacteriales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158463_k127_888564_4	1386089.N865_05570	9.134e-125	426.0	COG2834@1|root,COG2834@2|Bacteria,2GKA2@201174|Actinobacteria,4FJFY@85021|Intrasporangiaceae	201174|Actinobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092,MucB_RseB
SRR25158463_k127_888564_3	710696.Intca_0834	1.611e-130	443.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4FGUG@85021|Intrasporangiaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158463_k127_888564_5	710696.Intca_0835	2.462e-120	392.0	COG1277@1|root,COG1277@2|Bacteria,2GP6D@201174|Actinobacteria,4FH10@85021|Intrasporangiaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158463_k127_888564_6	1194165.CAJF01000015_gene1393	6.569e-113	368.0	COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
SRR25158463_k127_888564_1	1385518.N798_10510	6.46e-181	578.0	COG2141@1|root,COG4639@1|root,COG2141@2|Bacteria,COG4639@2|Bacteria,2GM7W@201174|Actinobacteria,4FG4X@85021|Intrasporangiaceae	201174|Actinobacteria	C	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
SRR25158463_k127_888564_0	1386089.N865_10050	1.528e-283	880.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FG72@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	alkK	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158463_k127_888564_2	1380370.JIBA01000006_gene3395	7.449e-138	448.0	COG4447@1|root,COG4447@2|Bacteria,2GMJN@201174|Actinobacteria,4FG48@85021|Intrasporangiaceae	201174|Actinobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
SRR25158463_k127_888564_7	101510.RHA1_ro03364	2.684e-73	264.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4FWMS@85025|Nocardiaceae	201174|Actinobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158463_k127_888564_11	1209984.BN978_01255	3.368e-49	181.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria,238UB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158463_k127_888564_8	1206744.BAGL01000006_gene3747	1.295e-66	235.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4FZWV@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158463_k127_888564_12	469383.Cwoe_2510	1.646e-29	121.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CR38@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158463_k127_920986_0	1380370.JIBA01000015_gene79	4.816e-291	897.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4FEJF@85021|Intrasporangiaceae	201174|Actinobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158463_k127_920986_5	1172188.KB911821_gene1785	7.077e-55	209.0	COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4FH1K@85021|Intrasporangiaceae	201174|Actinobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158463_k127_920986_3	367299.JOEE01000011_gene3182	1.329e-74	282.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4FF4T@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	pcl	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158463_k127_920986_1	1410634.JHVD01000025_gene537	5.042e-148	475.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4DPPU@85009|Propionibacteriales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158463_k127_920986_2	710696.Intca_3401	2.109e-134	440.0	COG2267@1|root,COG2267@2|Bacteria,2I44E@201174|Actinobacteria,4FGG5@85021|Intrasporangiaceae	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158463_k127_920986_4	1172186.KB911466_gene1223	2.754e-66	235.0	COG3832@1|root,COG3832@2|Bacteria,2IHY4@201174|Actinobacteria,239FM@1762|Mycobacteriaceae	201174|Actinobacteria	E	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158463_k127_920986_6	1283283.ATXA01000026_gene3678	3.485e-24	106.0	COG2350@1|root,COG3832@1|root,COG2350@2|Bacteria,COG3832@2|Bacteria,2IQZK@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158463_k127_920986_7	675635.Psed_0971	2.212e-17	81.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4DYTA@85010|Pseudonocardiales	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158463_k127_928286_2	367299.JOEE01000001_gene1895	7.945e-154	492.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4FE4Q@85021|Intrasporangiaceae	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158463_k127_928286_6	266940.Krad_0483	4.084e-33	141.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158463_k127_928286_0	1386089.N865_09425	0.0	1033.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4FE8S@85021|Intrasporangiaceae	201174|Actinobacteria	L	RNA helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158463_k127_928286_9	1120941.AUBL01000030_gene767	6.912e-08	61.0	2DRBM@1|root,33B4F@2|Bacteria,2HM1Z@201174|Actinobacteria,4D67X@85005|Actinomycetales	201174|Actinobacteria	S	TIGRFAM helicase secretion neighborhood TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158463_k127_928286_7	1385521.N803_10060	8.022e-12	70.0	2EGB2@1|root,33A2X@2|Bacteria,2HXV3@201174|Actinobacteria,4FHTK@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_928286_8	313589.JNB_09754	1.291e-09	61.0	2EHCF@1|root,33B4A@2|Bacteria,2HXWD@201174|Actinobacteria,4FI32@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF4244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4244
SRR25158463_k127_928286_3	1033730.CAHG01000012_gene2009	3.214e-113	370.0	COG2057@1|root,COG2057@2|Bacteria,2GKV9@201174|Actinobacteria,4DNCT@85009|Propionibacteriales	201174|Actinobacteria	I	Coenzyme A transferase	scoB	GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482	2.8.3.5,2.8.3.6	ko:K01029,ko:K01032	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2503c	CoA_trans
SRR25158463_k127_928286_4	350054.Mflv_0526	2.087e-107	359.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,235BR@1762|Mycobacteriaceae	201174|Actinobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	pcaI	-	2.8.3.5,2.8.3.6	ko:K01028,ko:K01031	ko00072,ko00280,ko00362,ko00650,ko01100,ko01120,map00072,map00280,map00362,map00650,map01100,map01120	-	R00410,R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158463_k127_928286_1	1121385.AQXW01000004_gene2327	6.13e-196	624.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,1ZWCE@145357|Dermacoccaceae	201174|Actinobacteria	I	Beta-ketoacyl synthase, N-terminal domain	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158463_k127_928286_5	1089453.GOSPT_056_00110	3.8e-61	214.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4GE31@85026|Gordoniaceae	201174|Actinobacteria	I	Carboxymuconolactone decarboxylase family	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
SRR25158463_k127_932703_2	1121933.AUHH01000046_gene2374	3.993e-81	293.0	COG2133@1|root,COG3291@1|root,COG5479@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4DVI3@85009|Propionibacteriales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SRR25158463_k127_932703_0	1380370.JIBA01000014_gene2139	2.841e-171	541.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4FEP9@85021|Intrasporangiaceae	201174|Actinobacteria	C	Molecular chaperone GroES	yogA	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158463_k127_932703_1	1386089.N865_17535	2.803e-159	529.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GJBR@201174|Actinobacteria,4FF4U@85021|Intrasporangiaceae	201174|Actinobacteria	D	FtsK/SpoIIIE family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Yop-YscD_cpl
SRR25158463_k127_946224_0	1172188.KB911830_gene3871	4.154e-222	695.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4FED8@85021|Intrasporangiaceae	201174|Actinobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158463_k127_946224_4	1123322.KB904636_gene2781	2.575e-62	229.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158463_k127_946224_2	710696.Intca_2889	1.793e-144	474.0	COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4FFQD@85021|Intrasporangiaceae	201174|Actinobacteria	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
SRR25158463_k127_946224_5	710696.Intca_2797	1.382e-26	111.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4FHNB@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158463_k127_946224_1	1283283.ATXA01000006_gene1945	4.321e-174	557.0	COG0477@1|root,COG2814@2|Bacteria,2I2IS@201174|Actinobacteria,4EXDZ@85013|Frankiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158463_k127_946224_3	710696.Intca_2796	1.478e-72	250.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4FGKA@85021|Intrasporangiaceae	201174|Actinobacteria	I	Belongs to the UPF0336 family	hadA	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158463_k127_946224_6	1386089.N865_03490	3.61e-19	95.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4FGSM@85021|Intrasporangiaceae	201174|Actinobacteria	I	dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158463_k127_952659_3	1380370.JIBA01000006_gene3396	5.329e-117	385.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4FI40@85021|Intrasporangiaceae	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,SE
SRR25158463_k127_952659_5	1121946.AUAX01000002_gene35	3.979e-46	179.0	COG1309@1|root,COG1309@2|Bacteria,2IKG3@201174|Actinobacteria,4DK2K@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158463_k127_952659_2	1121385.AQXW01000004_gene1595	2e-118	389.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,1ZVJJ@145357|Dermacoccaceae	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
SRR25158463_k127_952659_6	1146883.BLASA_2759	3.031e-34	142.0	COG3629@1|root,COG3629@2|Bacteria,2IC17@201174|Actinobacteria,4EVRF@85013|Frankiales	201174|Actinobacteria	T	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158463_k127_952659_9	1283283.ATXA01000006_gene1735	0.0008554	47.0	29F1V@1|root,301ZM@2|Bacteria,2HDWP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158463_k127_952659_0	1385520.N802_04205	1.84e-184	607.0	COG0455@1|root,COG1994@1|root,COG0455@2|Bacteria,COG1994@2|Bacteria,2GMK0@201174|Actinobacteria,4FGIH@85021|Intrasporangiaceae	201174|Actinobacteria	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158463_k127_952659_8	1151119.KB895489_gene560	0.0004299	52.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	-
SRR25158463_k127_952659_1	1032480.MLP_16870	9.532e-135	442.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4DQ8X@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158463_k127_952659_4	1323361.JPOC01000073_gene3676	1.427e-104	346.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4FXWF@85025|Nocardiaceae	201174|Actinobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add1	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158463_k127_974012_11	1121385.AQXW01000004_gene933	1.154e-55	218.0	COG1028@1|root,COG1028@2|Bacteria,2GJ0E@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158463_k127_974012_5	1380370.JIBA01000013_gene1567	7.816e-132	432.0	COG0237@1|root,COG2320@1|root,COG0237@2|Bacteria,COG2320@2|Bacteria,2GN96@201174|Actinobacteria,4FE98@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158463_k127_974012_1	1035308.AQYY01000001_gene1643	8.711e-227	718.0	COG1215@1|root,COG1215@2|Bacteria,1TSD3@1239|Firmicutes,248YQ@186801|Clostridia,2644S@186807|Peptococcaceae	186801|Clostridia	M	Glycosyl transferase family group 2	bcsA	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulase,Cellulose_synt,Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_21,Glycos_transf_2,PilZ
SRR25158463_k127_974012_13	767029.HMPREF9154_0641	4.726e-44	183.0	COG0845@1|root,COG0845@2|Bacteria,2IPE7@201174|Actinobacteria	201174|Actinobacteria	M	PFAM biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158463_k127_974012_3	1122997.AUDD01000004_gene1301	1.445e-180	594.0	COG5498@1|root,COG5498@2|Bacteria,2GNW3@201174|Actinobacteria	201174|Actinobacteria	M	glycoside hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_81
SRR25158463_k127_974012_14	287986.DV20_28835	1.038e-26	115.0	COG0251@1|root,COG0251@2|Bacteria,2I27U@201174|Actinobacteria,4E3ZR@85010|Pseudonocardiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158463_k127_974012_7	356851.JOAN01000016_gene6138	2.341e-95	320.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,4D97K@85008|Micromonosporales	201174|Actinobacteria	HP	ATPases associated with a variety of cellular activities	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158463_k127_974012_8	1121946.AUAX01000014_gene1090	1.201e-93	325.0	COG0614@1|root,COG0614@2|Bacteria,2GNIZ@201174|Actinobacteria,4D8PF@85008|Micromonosporales	201174|Actinobacteria	P	Periplasmic binding protein	fiuS3	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158463_k127_974012_2	644283.Micau_2593	1.01e-216	709.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4D8N1@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fiuP4	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158463_k127_974012_10	471853.Bcav_2292	1.758e-63	244.0	COG2375@1|root,COG2375@2|Bacteria,2GK5X@201174|Actinobacteria	201174|Actinobacteria	P	siderophore-interacting protein	sidE	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
SRR25158463_k127_974012_0	1386089.N865_00570	0.0	1217.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4FF7R@85021|Intrasporangiaceae	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158463_k127_974012_6	1385521.N803_08695	1.012e-107	359.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4FFA4@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	rhtA_1	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158463_k127_974012_4	1172188.KB911823_gene399	1.213e-143	465.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4FEUG@85021|Intrasporangiaceae	201174|Actinobacteria	P	Tellurium resistance protein TerC	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158463_k127_974012_12	512565.AMIS_52830	1.888e-46	175.0	COG2315@1|root,COG2315@2|Bacteria,2HR7I@201174|Actinobacteria,4DFE0@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158463_k127_974012_9	1386089.N865_00545	8.619e-74	258.0	COG0791@1|root,COG0791@2|Bacteria,2IFT3@201174|Actinobacteria,4FF29@85021|Intrasporangiaceae	201174|Actinobacteria	M	NlpC/P60 family	-	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	NLPC_P60
SRR25158463_k127_974012_15	1216976.AX27061_5685	1.214e-23	106.0	COG2367@1|root,COG2367@2|Bacteria,1N9HE@1224|Proteobacteria,2VYKR@28216|Betaproteobacteria,3T57Z@506|Alcaligenaceae	28216|Betaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
SRR25158463_k127_983946_4	1121017.AUFG01000014_gene2019	5.768e-50	178.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4FFP8@85021|Intrasporangiaceae	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158463_k127_983946_6	1386089.N865_20755	3.285e-28	120.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4FHVS@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158463_k127_983946_1	1193181.BN10_300061	3.119e-68	248.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4FG4W@85021|Intrasporangiaceae	201174|Actinobacteria	D	DivIVA protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158463_k127_983946_3	367299.JOEE01000004_gene1371	1.181e-50	194.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4FGBX@85021|Intrasporangiaceae	201174|Actinobacteria	T	DNA-binding protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158463_k127_983946_2	1380370.JIBA01000017_gene2845	9.14e-56	203.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4FHKI@85021|Intrasporangiaceae	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158463_k127_983946_0	1385521.N803_06655	2.419e-159	511.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4FFFW@85021|Intrasporangiaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158463_k127_983946_5	543632.JOJL01000048_gene7276	2.443e-48	192.0	COG1514@1|root,COG1514@2|Bacteria,2IKSA@201174|Actinobacteria,4DER1@85008|Micromonosporales	201174|Actinobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158463_k127_983946_7	479435.Kfla_2902	1.742e-15	80.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DN5X@85009|Propionibacteriales	201174|Actinobacteria	L	Bacterial DNA polymerase III alpha subunit	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158463_k127_996295_5	1283287.KB822580_gene1775	7.066e-05	46.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4DR5C@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158463_k127_996295_3	1386089.N865_08515	3.508e-81	275.0	COG2335@1|root,COG2335@2|Bacteria,2GJC2@201174|Actinobacteria,4FGIX@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fasciclin	mpt	GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158463_k127_996295_1	710696.Intca_0092	1.116e-187	601.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4FE2W@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158463_k127_996295_2	644283.Micau_5931	7.261e-145	468.0	COG0387@1|root,COG0387@2|Bacteria,2GJWT@201174|Actinobacteria,4D8I8@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	chaA	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	iNJ661.Rv1607	Na_Ca_ex
SRR25158463_k127_996295_4	1033730.CAHG01000015_gene732	9.272e-73	252.0	COG2808@1|root,COG2808@2|Bacteria,2IEXV@201174|Actinobacteria,4DR7Z@85009|Propionibacteriales	201174|Actinobacteria	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
SRR25158463_k127_996295_0	367299.JOEE01000002_gene2475	1.211e-195	626.0	COG2141@1|root,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria,4FEB3@85021|Intrasporangiaceae	201174|Actinobacteria	C	tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	BBE,Bac_luciferase,FAD_binding_4,Hemerythrin
## 2919 queries scanned
## Total time (seconds): 24.732264280319214
## Rate: 118.02 q/s