## Mon Dec 15 17:01:40 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158512_bin.5.fa -m mmseqs --itype genome -o SRR25158512_bin.5 --output_dir /data/result/bins/wyx/egg/SRR25158512_bin.5 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158512_k127_100944_2	1410620.SHLA_19c000550	2.899e-64	231.0	COG0589@1|root,COG0589@2|Bacteria,1RDNJ@1224|Proteobacteria,2UQMN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_100944_0	477641.MODMU_0519	4.36e-195	618.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4ERYR@85013|Frankiales	201174|Actinobacteria	E	Amino acid permease	rocE	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158512_k127_100944_1	710687.KI912270_gene396	1.567e-168	539.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,23EUD@1762|Mycobacteriaceae	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158512_k127_103067_0	42256.RradSPS_0729	1.371e-296	920.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CPS6@84995|Rubrobacteria	84995|Rubrobacteria	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158512_k127_103067_1	483219.LILAB_36240	7.851e-48	180.0	COG3000@1|root,COG3000@2|Bacteria,1NBCT@1224|Proteobacteria	1224|Proteobacteria	I	B domain of TMEM189, localisation domain	carF	-	-	ko:K20656	-	-	-	-	ko00000,ko04131	-	-	-	TMEM189_B_dmain
SRR25158512_k127_1035824_5	502025.Hoch_3849	3.11e-23	105.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
SRR25158512_k127_1035824_2	266117.Rxyl_1416	3.553e-109	361.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CPIB@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158512_k127_1035824_4	479434.Sthe_0444	3.488e-39	161.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
SRR25158512_k127_1035824_3	266117.Rxyl_1417	1.723e-39	149.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CQF0@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158512_k127_1035824_0	266117.Rxyl_1418	0.0	1082.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CPRU@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158512_k127_1035824_1	42256.RradSPS_1424	9.212e-208	654.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158512_k127_1051689_1	266117.Rxyl_1145	1.022e-81	278.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CQ6Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SRR25158512_k127_1051689_2	266117.Rxyl_1146	3.467e-61	214.0	2ES9W@1|root,33JUM@2|Bacteria,2GWZY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1051689_0	266117.Rxyl_1147	1.299e-104	347.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CP9J@84995|Rubrobacteria	84995|Rubrobacteria	L	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158512_k127_1060769_2	701347.Entcl_2579	1.108e-19	95.0	COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,1RZPC@1236|Gammaproteobacteria,3X3HS@547|Enterobacter	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158512_k127_1060769_0	1120985.AUMI01000014_gene710	1.54e-47	183.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4H3T7@909932|Negativicutes	909932|Negativicutes	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158512_k127_1060769_1	1121468.AUBR01000029_gene1575	5.709e-43	170.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,42GI1@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Monogalactosyldiacylglycerol synthase	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
SRR25158512_k127_1109807_0	42256.RradSPS_1468	4.41e-142	456.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CPJG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158512_k127_1109807_1	266117.Rxyl_0080	1.461e-117	384.0	COG1028@1|root,COG1028@2|Bacteria	266117.Rxyl_0080|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1109807_4	266117.Rxyl_1463	1.481e-42	166.0	COG3167@1|root,COG3167@2|Bacteria,2I81H@201174|Actinobacteria	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein M	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SRR25158512_k127_1109807_3	266117.Rxyl_1464	7.245e-60	218.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SRR25158512_k127_1109807_2	266117.Rxyl_1465	8.658e-99	330.0	COG4972@1|root,COG4972@2|Bacteria,2IBNF@201174|Actinobacteria,4CQH2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SRR25158512_k127_1114888_0	266117.Rxyl_2032	2.159e-151	490.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CPCG@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158512_k127_111600_3	266117.Rxyl_3063	1.759e-28	120.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_111600_2	42256.RradSPS_2502	1.27e-83	282.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Putative_PNPOx
SRR25158512_k127_111600_0	42256.RradSPS_2501	1.569e-152	492.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria,4CQUX@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase M20	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158512_k127_111600_1	42256.RradSPS_2500	7.411e-99	330.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1611,DUF1611_N,Peptidase_S8
SRR25158512_k127_1121649_2	266117.Rxyl_2907	1.008e-177	559.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4CRIV@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158512_k127_1121649_3	562970.Btus_3086	1.2e-144	473.0	COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,27ASU@186823|Alicyclobacillaceae	91061|Bacilli	E	Amino acid permease	gabP	-	-	ko:K11735	-	-	-	-	ko00000,ko02000	2.A.3.1.4,2.A.3.1.5	-	iYO844.BSU06310	AA_permease
SRR25158512_k127_1121649_0	266117.Rxyl_1906	6.221e-195	626.0	COG0006@1|root,COG0006@2|Bacteria,2HFXD@201174|Actinobacteria,4CTAC@84995|Rubrobacteria	84995|Rubrobacteria	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158512_k127_1121649_1	266117.Rxyl_2908	2.184e-186	587.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4CRZC@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158512_k127_1128893_3	42256.RradSPS_0061	1.017e-28	115.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4CPEH@84995|Rubrobacteria	84995|Rubrobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158512_k127_1128893_2	489825.LYNGBM3L_21480	7.997e-46	168.0	2DNS7@1|root,32YWC@2|Bacteria,1G8QD@1117|Cyanobacteria,1HGCH@1150|Oscillatoriales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158512_k127_1128893_0	42256.RradSPS_0062	1.979e-253	789.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CPHW@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158512_k127_1128893_1	266117.Rxyl_0052	1.457e-88	302.0	COG3429@1|root,COG3429@2|Bacteria,2HYJH@201174|Actinobacteria,4CPZH@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158512_k127_113320_3	266117.Rxyl_3010	1.035e-87	295.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4CSY8@84995|Rubrobacteria	84995|Rubrobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_113320_2	266117.Rxyl_3009	6.122e-95	319.0	COG4221@1|root,COG4221@2|Bacteria,2IG9V@201174|Actinobacteria	201174|Actinobacteria	S	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_113320_0	450851.PHZ_c2466	4.318e-301	931.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2KFMP@204458|Caulobacterales	204458|Caulobacterales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22186	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
SRR25158512_k127_113320_7	1297570.MESS4_670078	2.006e-10	66.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,43N64@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_113320_6	42256.RradSPS_0622	3.771e-11	75.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
SRR25158512_k127_113320_1	266117.Rxyl_3007	1.79e-113	370.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CT7G@84995|Rubrobacteria	84995|Rubrobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_113320_4	1499967.BAYZ01000073_gene2029	7.06e-79	270.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158512_k127_113320_5	266117.Rxyl_0757	1.565e-64	225.0	COG1292@1|root,COG1292@2|Bacteria,2GJX0@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
SRR25158512_k127_1136745_2	1122915.AUGY01000043_gene7831	1.235e-51	187.0	COG1028@1|root,COG1028@2|Bacteria,1UV9Y@1239|Firmicutes,4I3D5@91061|Bacilli,26YU8@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_1136745_3	172088.AUGA01000017_gene2334	2.083e-11	74.0	COG2931@1|root,COG2931@2|Bacteria,1RBME@1224|Proteobacteria,2U5CZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	wgeA	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_1136745_0	266117.Rxyl_0159	1.721e-89	327.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4CQ9Z@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_1136745_1	266117.Rxyl_0160	2.315e-74	256.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4CQ2W@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_1169049_0	42256.RradSPS_2762	2.653e-70	251.0	COG1836@1|root,COG1836@2|Bacteria	2|Bacteria	I	PFAM Integral membrane protein DUF92	-	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	DUF92
SRR25158512_k127_1169049_1	266117.Rxyl_3205	9.05e-44	161.0	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
SRR25158512_k127_1183745_0	42256.RradSPS_2310	3.442e-83	289.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0008150,GO:0040007	4.2.1.113,5.1.1.20,5.1.1.3	ko:K01776,ko:K02549,ko:K19802	ko00130,ko00471,ko01100,ko01110,map00130,map00471,map01100,map01110	M00116	R00260,R04031,R10938	RC00302,RC01053,RC03309	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	iNJ661.Rv0553,iSB619.SA_RS09080	MR_MLE_C
SRR25158512_k127_1183745_1	479435.Kfla_6818	5.115e-18	89.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,4DRPH@85009|Propionibacteriales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158512_k127_1188083_8	469383.Cwoe_0346	1.931e-51	186.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CPI3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_1188083_4	42256.RradSPS_2860	2.866e-62	219.0	COG1073@1|root,COG1073@2|Bacteria,2I2NV@201174|Actinobacteria	201174|Actinobacteria	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
SRR25158512_k127_1188083_1	391037.Sare_3034	1.338e-83	285.0	COG0596@1|root,COG0596@2|Bacteria,2I32Y@201174|Actinobacteria,4DDH9@85008|Micromonosporales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_1188083_2	485913.Krac_0746	1.245e-68	244.0	COG1028@1|root,COG1028@2|Bacteria	485913.Krac_0746|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1188083_9	42256.RradSPS_2858	1.731e-49	182.0	COG4270@1|root,COG4270@2|Bacteria,2GQJP@201174|Actinobacteria	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158512_k127_1188083_0	42256.RradSPS_2865	2.891e-143	471.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4CQP7@84995|Rubrobacteria	84995|Rubrobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158512_k127_1188083_10	749927.AMED_2743	7.215e-25	110.0	COG0346@1|root,COG0346@2|Bacteria,2IKBZ@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_1188083_5	479432.Sros_6982	2.664e-56	201.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4EJS4@85012|Streptosporangiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1188083_3	580332.Slit_2328	7.06e-63	229.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1188083_7	42256.RradSPS_1852	4.632e-54	193.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4CT04@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_1188083_6	208444.JNYY01000005_gene6258	1.192e-55	199.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria,4E47B@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1192079_4	266117.Rxyl_0182	8.513e-53	188.0	COG0662@1|root,COG0662@2|Bacteria,2IPIR@201174|Actinobacteria	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K01809,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer
SRR25158512_k127_1192079_3	266117.Rxyl_0191	1.367e-64	224.0	COG0633@1|root,COG0633@2|Bacteria	2|Bacteria	C	Ferredoxin	fdx5	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
SRR25158512_k127_1192079_0	266117.Rxyl_0211	7.891e-163	518.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CU1U@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_1192079_2	266117.Rxyl_0212	1.35e-71	246.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,4CQR4@84995|Rubrobacteria	84995|Rubrobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158512_k127_1192079_1	1007103.AFHW01000079_gene4227	2.286e-108	361.0	COG3214@1|root,COG3214@2|Bacteria,1UYQ5@1239|Firmicutes,4HE15@91061|Bacilli,26U3N@186822|Paenibacillaceae	91061|Bacilli	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158512_k127_1198535_0	266117.Rxyl_2973	1.898e-225	703.0	COG0438@1|root,COG0438@2|Bacteria,2ICGI@201174|Actinobacteria,4CPFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
SRR25158512_k127_1198535_1	266117.Rxyl_2974	6.164e-45	167.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbT	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2,SpoIIE
SRR25158512_k127_1198535_2	266117.Rxyl_2976	2.452e-20	102.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,2GIWB@201174|Actinobacteria,4CPUW@84995|Rubrobacteria	84995|Rubrobacteria	M	NlpC/P60 family	-	-	-	ko:K21473	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,PG_binding_1
SRR25158512_k127_1206465_0	1123321.KB905817_gene5040	2.209e-150	490.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158512_k127_1206465_3	1122611.KB903941_gene2216	3.38e-07	58.0	2BATK@1|root,3248V@2|Bacteria,2H93C@201174|Actinobacteria,4EQ6G@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1206465_2	469383.Cwoe_3842	3.706e-31	130.0	COG0262@1|root,COG0262@2|Bacteria,2HG3A@201174|Actinobacteria,4CTPW@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1206465_1	1380356.JNIK01000003_gene1100	2.633e-59	207.0	COG0262@1|root,COG0262@2|Bacteria,2I9MN@201174|Actinobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1212785_3	489825.LYNGBM3L_55270	2.677e-16	87.0	COG1357@1|root,COG1357@2|Bacteria,1G42W@1117|Cyanobacteria,1H9P7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158512_k127_1212785_2	42256.RradSPS_0622	5.717e-19	91.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
SRR25158512_k127_1212785_5	103733.JNYO01000006_gene1803	3.664e-05	51.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Calx-beta,DUF4347,HemolysinCabind,VCBS,W_rich_C
SRR25158512_k127_1212785_0	101510.RHA1_ro01226	9.109e-69	248.0	COG0596@1|root,COG0596@2|Bacteria,2IAVM@201174|Actinobacteria,4G8K9@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158512_k127_1212785_1	266117.Rxyl_3157	1.748e-53	193.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	dpnA	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158512_k127_122188_1	1128421.JAGA01000003_gene3260	1.565e-135	473.0	COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158512_k127_122188_2	266117.Rxyl_2290	7.467e-115	377.0	COG0639@1|root,COG0639@2|Bacteria,2HNQI@201174|Actinobacteria,4CPX1@84995|Rubrobacteria	84995|Rubrobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158512_k127_122188_4	42256.RradSPS_0526	1.937e-56	199.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158512_k127_122188_3	266117.Rxyl_2291	4.877e-57	203.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4CQCM@84995|Rubrobacteria	84995|Rubrobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158512_k127_122188_0	316274.Haur_4945	8.284e-153	492.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	2|Bacteria	S	PFAM ABC transporter related	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158512_k127_1232657_6	266117.Rxyl_1015	1.722e-31	126.0	COG2127@1|root,COG2127@2|Bacteria	2|Bacteria	T	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158512_k127_1232657_1	42256.RradSPS_0971	1.176e-191	600.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4CQBI@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR25158512_k127_1232657_3	266117.Rxyl_1274	6.943e-128	423.0	COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria	201174|Actinobacteria	P	Potassium uptake protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158512_k127_1232657_5	266117.Rxyl_1021	6.745e-46	171.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	CBS,DUF190
SRR25158512_k127_1232657_2	266117.Rxyl_1020	4.932e-172	549.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CS0G@84995|Rubrobacteria	201174|Actinobacteria	P	Arsenical pump membrane protein	arsA	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
SRR25158512_k127_1232657_0	266117.Rxyl_1023	4.174e-221	701.0	COG0297@1|root,COG0297@2|Bacteria,2I4BF@201174|Actinobacteria,4CU41@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SRR25158512_k127_1232657_4	42256.RradSPS_0988	4.539e-55	198.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158512_k127_123711_5	266117.Rxyl_0440	2.613e-10	61.0	COG1309@1|root,COG1309@2|Bacteria,2HFWT@201174|Actinobacteria,4CTT8@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158512_k127_123711_3	694430.Natoc_0239	4.491e-43	161.0	arCOG10217@1|root,arCOG10217@2157|Archaea,2XXAS@28890|Euryarchaeota,23VMU@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF4385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4385
SRR25158512_k127_123711_1	266117.Rxyl_0443	1.003e-149	482.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4CP5Z@84995|Rubrobacteria	84995|Rubrobacteria	O	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158512_k127_123711_0	266117.Rxyl_0444	4.59e-170	541.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CQ1M@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158512_k127_123711_2	266117.Rxyl_0445	1.355e-62	218.0	COG3402@1|root,COG3402@2|Bacteria,2GSY6@201174|Actinobacteria,4CQQX@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158512_k127_1240065_3	1116369.KB890024_gene70	1.208e-56	201.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	y2-aiiA	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158512_k127_1240065_6	68260.JOAY01000039_gene2234	3.522e-05	46.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_1240065_4	1463858.JOHR01000013_gene2720	2.477e-24	106.0	2D7MD@1|root,32TP9@2|Bacteria,2IRM1@201174|Actinobacteria	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158512_k127_1240065_1	485913.Krac_3442	1.11e-146	481.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158512_k127_1240065_0	314230.DSM3645_22154	1.614e-175	565.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	CW_binding_1,Lactamase_B
SRR25158512_k127_1240065_2	1125971.ASJB01000065_gene6214	2.808e-81	273.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DX88@85010|Pseudonocardiales	201174|Actinobacteria	EG	Belongs to the IlvD Edd family	araC	-	4.2.1.82,4.2.1.9	ko:K01687,ko:K22186	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158512_k127_1242321_1	1210884.HG799474_gene15149	2.652e-66	239.0	COG0524@1|root,COG0524@2|Bacteria,2IWUH@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158512_k127_1242321_0	266117.Rxyl_0179	2.768e-78	269.0	COG0740@1|root,COG0740@2|Bacteria,2GZZC@201174|Actinobacteria	201174|Actinobacteria	OU	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1242321_2	266117.Rxyl_0178	5.133e-45	167.0	2DMMR@1|root,32SHV@2|Bacteria,2IQA6@201174|Actinobacteria,4CQSK@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158512_k127_1244136_1	1146883.BLASA_1379	9.405e-72	243.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158512_k127_1244136_2	263358.VAB18032_24305	2.025e-44	176.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DGTB@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_1244136_3	1223543.GP2_003_01050	2.833e-29	126.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158512_k127_1244136_4	1123228.AUIH01000076_gene3933	7.474e-12	76.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XKU1@135619|Oceanospirillales	135619|Oceanospirillales	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,HemolysinCabind,Laminin_G_3
SRR25158512_k127_1244136_0	42256.RradSPS_2830	1.608e-86	299.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07506,ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC,Response_reg
SRR25158512_k127_1247001_2	211114.JOEF01000012_gene5109	4.005e-51	184.0	COG1846@1|root,COG1846@2|Bacteria,2IKND@201174|Actinobacteria,4E4ZM@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158512_k127_1247001_0	266117.Rxyl_3059	1.587e-150	484.0	COG4656@1|root,COG4656@2|Bacteria	2|Bacteria	C	electron transfer activity	citB	-	-	ko:K03616,ko:K13795	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer2,Fer2_4,Fer4_17,Fer4_7,Fer4_8,NQR2_RnfD_RnfE,RnfC_N
SRR25158512_k127_1247001_3	266117.Rxyl_1196	5.672e-41	152.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4CQEK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158512_k127_1247001_1	266117.Rxyl_1633	5.061e-128	410.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CPGB@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158512_k127_1247788_1	266117.Rxyl_0604	4.933e-33	129.0	COG2710@1|root,COG2710@2|Bacteria	2|Bacteria	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein	chlB	-	1.3.7.7	ko:K02587,ko:K04038,ko:K04039	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
SRR25158512_k127_1247788_0	266117.Rxyl_0601	3.803e-122	404.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	201174|Actinobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158512_k127_1267614_2	42256.RradSPS_0470	2.206e-74	258.0	COG0340@1|root,COG0340@2|Bacteria,2HGFP@201174|Actinobacteria,4CQNA@84995|Rubrobacteria	84995|Rubrobacteria	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158512_k127_1267614_0	42256.RradSPS_0825	9.976e-153	492.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4CQ14@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
SRR25158512_k127_1267614_1	42256.RradSPS_0824	6.734e-139	447.0	COG2138@1|root,COG2138@2|Bacteria,2GS51@201174|Actinobacteria,4CU1K@84995|Rubrobacteria	84995|Rubrobacteria	S	cobalamin (vitamin B12) biosynthesis CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
SRR25158512_k127_1267614_3	42256.RradSPS_0823	1.238e-27	113.0	COG2082@1|root,COG2082@2|Bacteria,2GK0B@201174|Actinobacteria,4CQ19@84995|Rubrobacteria	84995|Rubrobacteria	H	Precorrin-8X methylmutase	-	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
SRR25158512_k127_1277356_0	42256.RradSPS_1835	5.887e-144	492.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRIR@84995|Rubrobacteria	84995|Rubrobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
SRR25158512_k127_1277356_2	266117.Rxyl_2857	6.714e-57	211.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3703,PAP2
SRR25158512_k127_1277356_5	266117.Rxyl_2861	1.465e-31	124.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
SRR25158512_k127_1277356_3	266117.Rxyl_2862	1.55e-53	193.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CSW8@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158512_k127_1278486_2	266117.Rxyl_0991	2.752e-92	306.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CP95@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158512_k127_1278486_0	42256.RradSPS_0903	1.072e-232	728.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CPAP@84995|Rubrobacteria	84995|Rubrobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158512_k127_1278486_1	42256.RradSPS_0902	7.708e-171	546.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4CQB2@84995|Rubrobacteria	84995|Rubrobacteria	G	COG COG1653 ABC-type sugar transport system periplasmic component Carbohydrate transport and metabolism	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158512_k127_1294580_1	266117.Rxyl_0964	2.859e-177	559.0	COG1035@1|root,COG2878@1|root,COG1035@2|Bacteria,COG2878@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158512_k127_1294580_4	266117.Rxyl_0965	2.696e-32	128.0	297P3@1|root,2ZUW0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1294580_0	42256.RradSPS_0877	1.861e-185	591.0	COG2046@1|root,COG2046@2|Bacteria,2IHS5@201174|Actinobacteria	201174|Actinobacteria	H	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158512_k127_1294580_3	266117.Rxyl_0967	4.288e-91	302.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria,4CTDY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of activated sulfate	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158512_k127_1294580_2	266117.Rxyl_0968	7.839e-107	352.0	COG0730@1|root,COG0730@2|Bacteria,2GNW8@201174|Actinobacteria,4CRVC@84995|Rubrobacteria	84995|Rubrobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158512_k127_1294580_5	1463895.JODA01000019_gene7344	1.003e-09	68.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
SRR25158512_k127_1295605_2	42256.RradSPS_0479	3.596e-110	360.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CPBA@84995|Rubrobacteria	84995|Rubrobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158512_k127_1295605_5	373994.Riv7116_3702	1.955e-14	81.0	COG2931@1|root,COG2931@2|Bacteria,1G5I4@1117|Cyanobacteria,1HPTC@1161|Nostocales	1117|Cyanobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_1295605_3	266117.Rxyl_2326	7.77e-61	214.0	COG0127@1|root,COG0127@2|Bacteria,2IT21@201174|Actinobacteria,4CU38@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the HAM1 NTPase family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158512_k127_1295605_1	266117.Rxyl_2325	8.573e-178	563.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4CS4C@84995|Rubrobacteria	84995|Rubrobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158512_k127_1295605_0	266117.Rxyl_2324	1.546e-192	602.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CRUB@84995|Rubrobacteria	84995|Rubrobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158512_k127_1295605_4	42256.RradSPS_0483	1.221e-45	168.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4CPDS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
SRR25158512_k127_1295801_1	42256.RradSPS_0552	1.191e-107	354.0	COG1092@1|root,COG1092@2|Bacteria,2I33B@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158512_k127_1295801_0	1173022.Cri9333_3469	1.353e-198	625.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158512_k127_1306282_2	1382306.JNIM01000001_gene3594	1.914e-144	473.0	COG4987@1|root,COG4987@2|Bacteria,2GA7U@200795|Chloroflexi	200795|Chloroflexi	V	TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	-	-	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158512_k127_1306282_0	42256.RradSPS_3068	1.095e-233	729.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4CPFN@84995|Rubrobacteria	84995|Rubrobacteria	C	ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158512_k127_1306282_1	42256.RradSPS_3067	9.091e-169	535.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4CQE5@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158512_k127_1306282_3	42256.RradSPS_3060	9.201e-26	109.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPG7@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_1314954_0	266117.Rxyl_2808	1.472e-172	546.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPY2@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158512_k127_1314954_1	266117.Rxyl_2807	5.306e-148	473.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CQKB@84995|Rubrobacteria	84995|Rubrobacteria	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158512_k127_1314954_3	266117.Rxyl_2805	1.422e-87	292.0	COG1432@1|root,COG1432@2|Bacteria,2HABB@201174|Actinobacteria	201174|Actinobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158512_k127_1314954_4	266117.Rxyl_2804	1.039e-38	147.0	COG1366@1|root,COG1366@2|Bacteria,2HPDG@201174|Actinobacteria,4CQRG@84995|Rubrobacteria	84995|Rubrobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158512_k127_1314954_2	42256.RradSPS_2445	4.337e-111	363.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CQTJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158512_k127_132107_9	266117.Rxyl_2816	7.575e-11	62.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158512_k127_132107_6	266117.Rxyl_2816	6.885e-63	219.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158512_k127_132107_8	266117.Rxyl_2818	4.23e-54	194.0	COG0597@1|root,COG0597@2|Bacteria,2HP4E@201174|Actinobacteria,4CQFY@84995|Rubrobacteria	84995|Rubrobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158512_k127_132107_5	266117.Rxyl_2828	4.698e-91	304.0	COG1435@1|root,COG1435@2|Bacteria	2|Bacteria	F	thymidine kinase activity	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iLJ478.TM0401	TK
SRR25158512_k127_132107_3	266117.Rxyl_2830	6.506e-124	403.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CQ9A@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158512_k127_132107_1	266117.Rxyl_2831	5.038e-243	758.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria	201174|Actinobacteria	C	Fe-S oxidoreductase	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
SRR25158512_k127_132107_2	266117.Rxyl_2832	2.56e-140	460.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CRXQ@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158512_k127_132107_0	266117.Rxyl_2833	2.924e-271	839.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CPWI@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158512_k127_132107_4	42256.RradSPS_1313	1.686e-99	328.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4CQE1@84995|Rubrobacteria	84995|Rubrobacteria	I	6-phosphogluconate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158512_k127_1327341_0	266117.Rxyl_0368	1.868e-147	471.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4CSTP@84995|Rubrobacteria	84995|Rubrobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158512_k127_1327341_2	266117.Rxyl_2347	2.137e-80	273.0	COG3917@1|root,COG3917@2|Bacteria,2HPCS@201174|Actinobacteria,4CQQS@84995|Rubrobacteria	84995|Rubrobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158512_k127_1327341_1	1122939.ATUD01000007_gene2104	3.81e-96	330.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria,4CR7R@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_1335145_0	266117.Rxyl_0150	1.598e-139	447.0	COG0471@1|root,COG0471@2|Bacteria,2GVHZ@201174|Actinobacteria,4CRW1@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
SRR25158512_k127_1335145_1	266117.Rxyl_1350	4.447e-135	439.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4CPB8@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158512_k127_1335145_3	797209.ZOD2009_21847	7.037e-87	293.0	COG1028@1|root,arCOG01259@2157|Archaea,2XV13@28890|Euryarchaeota,23URP@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_1335145_4	504832.OCAR_6784	2.907e-11	71.0	COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,2U66D@28211|Alphaproteobacteria,3JV68@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
SRR25158512_k127_1335145_2	40571.JOEA01000005_gene4054	5.134e-91	309.0	COG0702@1|root,COG0702@2|Bacteria,2GK1A@201174|Actinobacteria,4E577@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR25158512_k127_1346602_1	118161.KB235922_gene1687	4.314e-91	312.0	COG1028@1|root,COG1028@2|Bacteria,1GCUE@1117|Cyanobacteria,3VM0W@52604|Pleurocapsales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_1346602_3	1206733.BAGC01000071_gene4150	6.919e-27	117.0	COG1309@1|root,COG1309@2|Bacteria,2GSQP@201174|Actinobacteria,4G4SU@85025|Nocardiaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158512_k127_1346602_4	1227739.Hsw_0846	4.247e-15	82.0	2E6DR@1|root,3311A@2|Bacteria,4NWX0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1346602_2	266117.Rxyl_2607	3.988e-72	256.0	COG0697@1|root,COG0697@2|Bacteria,2H1HG@201174|Actinobacteria,4CQ2H@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_1346602_0	485913.Krac_0656	4.546e-255	803.0	COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi	2|Bacteria	G	glycoside hydrolase family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158512_k127_1351792_2	136273.GY22_08120	9.766e-15	79.0	2BG4A@1|root,32A10@2|Bacteria,2HTN7@201174|Actinobacteria,1WBWP@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1351792_1	266117.Rxyl_2592	1.322e-65	233.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158512_k127_1351792_0	266117.Rxyl_2593	1.446e-152	491.0	COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	NIF3
SRR25158512_k127_1353900_3	869210.Marky_1921	1.229e-23	105.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158512_k127_1353900_1	266117.Rxyl_0152	2.333e-102	340.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158512_k127_1353900_2	266117.Rxyl_0153	4.335e-28	114.0	COG1655@1|root,COG1655@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
SRR25158512_k127_1363195_1	266117.Rxyl_0578	1.363e-94	315.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,4CPPK@84995|Rubrobacteria	84995|Rubrobacteria	E	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158512_k127_1363195_2	266117.Rxyl_0579	2.25e-82	279.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria,4CT80@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158512_k127_1363195_0	266117.Rxyl_0982	1.135e-131	428.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4CPP5@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158512_k127_1363195_3	103733.JNYO01000002_gene480	1.063e-38	145.0	COG1476@1|root,COG1476@2|Bacteria,2IRJP@201174|Actinobacteria,4E5BS@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158512_k127_1364180_2	42256.RradSPS_1324	4.561e-60	209.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CPCE@84995|Rubrobacteria	84995|Rubrobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158512_k127_1364180_0	479434.Sthe_0485	2.85e-144	486.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
SRR25158512_k127_1364180_1	42256.RradSPS_2744	4.72e-65	228.0	COG2197@1|root,COG2197@2|Bacteria,2GPKD@201174|Actinobacteria,4CQCW@84995|Rubrobacteria	84995|Rubrobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158512_k127_1364858_3	266117.Rxyl_0174	9.488e-81	274.0	COG0546@1|root,COG0546@2|Bacteria,2GIU8@201174|Actinobacteria,4CPZN@84995|Rubrobacteria	84995|Rubrobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158512_k127_1364858_2	266117.Rxyl_0173	8.076e-81	281.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,4CQCX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158512_k127_1364858_4	234267.Acid_4717	2.323e-29	126.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
SRR25158512_k127_1364858_0	266117.Rxyl_0171	1.608e-136	437.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CPSF@84995|Rubrobacteria	84995|Rubrobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158512_k127_1364858_1	42256.RradSPS_2723	3.869e-93	306.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158512_k127_1368214_1	484770.UFO1_3024	4.006e-160	522.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4H2RI@909932|Negativicutes	909932|Negativicutes	C	permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
SRR25158512_k127_1368214_0	266117.Rxyl_2854	6.415e-169	547.0	COG2379@1|root,COG2379@2|Bacteria,2GXVW@201174|Actinobacteria	201174|Actinobacteria	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158512_k127_1368214_2	266117.Rxyl_2851	1.547e-124	404.0	COG3622@1|root,COG3622@2|Bacteria,2GKPC@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the hyi family	hyi	-	5.3.1.22,5.3.1.35	ko:K01816,ko:K22131	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158512_k127_1368214_3	266117.Rxyl_2852	4.201e-53	190.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4CQE1@84995|Rubrobacteria	84995|Rubrobacteria	I	6-phosphogluconate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158512_k127_1373485_0	42256.RradSPS_2290	6.717e-201	630.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158512_k127_1373485_1	266117.Rxyl_2873	1.324e-134	435.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4CPB0@84995|Rubrobacteria	84995|Rubrobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158512_k127_1373485_2	485913.Krac_6992	1.745e-67	246.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_1385822_3	266117.Rxyl_0225	3.948e-92	306.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158512_k127_1385822_2	266117.Rxyl_0226	1.266e-106	353.0	COG0619@1|root,COG0619@2|Bacteria,2GUVM@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158512_k127_1385822_1	266117.Rxyl_0227	1.369e-127	414.0	COG0697@1|root,COG0697@2|Bacteria,2GZ3P@201174|Actinobacteria	201174|Actinobacteria	EG	spore germination	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	QueT
SRR25158512_k127_1385822_0	42256.RradSPS_2985	5.948e-217	678.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4CS1V@84995|Rubrobacteria	84995|Rubrobacteria	H	S-adenosyl-L-homocysteine hydrolase	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158512_k127_1385822_4	42256.RradSPS_0074	8.292e-37	141.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CP86@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158512_k127_1386543_7	631362.Thi970DRAFT_02178	6.731e-15	79.0	2A6UU@1|root,30VP8@2|Bacteria,1NQ5B@1224|Proteobacteria,1SUYT@1236|Gammaproteobacteria,1X1Y1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1386543_2	266117.Rxyl_0684	1.941e-61	215.0	COG1765@1|root,COG1765@2|Bacteria,2IIUB@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158512_k127_1386543_0	266117.Rxyl_2533	6.623e-153	488.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CQB3@84995|Rubrobacteria	84995|Rubrobacteria	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158512_k127_1386543_4	266117.Rxyl_1617	5.736e-46	177.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158512_k127_1386543_5	266117.Rxyl_1618	6.677e-40	152.0	COG2391@1|root,COG2391@2|Bacteria,2I94E@201174|Actinobacteria,4CQVD@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158512_k127_1386543_3	266117.Rxyl_1661	8.097e-59	208.0	COG1247@1|root,COG1247@2|Bacteria,2H1MI@201174|Actinobacteria,4CQH6@84995|Rubrobacteria	84995|Rubrobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158512_k127_1386543_6	1128421.JAGA01000002_gene910	5.071e-29	119.0	2DQ8Q@1|root,335AV@2|Bacteria,2NQY5@2323|unclassified Bacteria	2|Bacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158512_k127_1386543_9	1230341.MJ3_03762	1.881e-06	57.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli	91061|Bacilli	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	ytcI	GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158512_k127_1386543_8	266117.Rxyl_2531	9.055e-11	70.0	COG0365@1|root,COG0365@2|Bacteria,2GJSQ@201174|Actinobacteria,4CRGY@84995|Rubrobacteria	84995|Rubrobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158512_k127_1386543_1	886293.Sinac_4765	4.264e-76	272.0	COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes	203682|Planctomycetes	U	Pkd domain containing protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	-
SRR25158512_k127_1390565_1	42256.RradSPS_0920	7.206e-147	469.0	COG1984@1|root,COG1984@2|Bacteria,2GITH@201174|Actinobacteria,4CREH@84995|Rubrobacteria	84995|Rubrobacteria	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
SRR25158512_k127_1390565_2	42256.RradSPS_0921	2.98e-115	376.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4CQDG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR25158512_k127_1390565_3	42256.RradSPS_0922	3.4e-28	115.0	COG0511@1|root,COG0511@2|Bacteria	2|Bacteria	I	ligase activity, forming carbon-carbon bonds	accB	-	2.3.1.12,2.3.1.39,4.1.1.3	ko:K00627,ko:K00645,ko:K01572,ko:K02160	ko00010,ko00020,ko00061,ko00333,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00333,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R01626,R02569,R11671	RC00004,RC00039,RC00040,RC00367,RC02727,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko01004,ko02000	3.B.1.1.1	-	-	Acyl_transf_1,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158512_k127_1390565_0	42256.RradSPS_0923	2.24e-266	836.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CS94@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158512_k127_1395394_0	42256.RradSPS_3020	1.277e-242	758.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CPE7@84995|Rubrobacteria	84995|Rubrobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158512_k127_1395394_1	42256.RradSPS_0060	4.618e-100	333.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CSJN@84995|Rubrobacteria	84995|Rubrobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158512_k127_1395801_3	110319.CF8_3973	2.87e-45	168.0	COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria,4DRI0@85009|Propionibacteriales	201174|Actinobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158512_k127_1395801_0	266117.Rxyl_1821	8.047e-96	322.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4CQ2F@84995|Rubrobacteria	84995|Rubrobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158512_k127_1395801_1	266117.Rxyl_0058	1.186e-95	319.0	COG0095@1|root,COG0095@2|Bacteria,2IG61@201174|Actinobacteria,4CTQ7@84995|Rubrobacteria	84995|Rubrobacteria	H	biotin lipoate A B protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1395801_5	386456.JQKN01000004_gene184	4.234e-11	74.0	arCOG02555@1|root,arCOG07611@1|root,arCOG02555@2157|Archaea,arCOG07611@2157|Archaea	2157|Archaea	E	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Chlam_PMP,DUF11
SRR25158512_k127_1395801_2	1246995.AFR_20265	2.68e-57	208.0	COG4424@1|root,COG4424@2|Bacteria,2GNGY@201174|Actinobacteria,4DK92@85008|Micromonosporales	201174|Actinobacteria	S	Stf0 sulphotransferase	stf0	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
SRR25158512_k127_1395801_4	247634.GPB2148_3889	2.686e-40	153.0	COG1309@1|root,COG1309@2|Bacteria,1RG02@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_140232_5	42256.RradSPS_0912	5.437e-22	96.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CPN1@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158512_k127_140232_4	234621.RER_29830	7.671e-29	122.0	2EQV0@1|root,33IET@2|Bacteria,2IM90@201174|Actinobacteria,4G2RH@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_140232_2	1382306.JNIM01000001_gene2347	2.938e-47	175.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158512_k127_140232_1	266117.Rxyl_0998	2.955e-160	514.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CP9S@84995|Rubrobacteria	84995|Rubrobacteria	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158512_k127_140232_3	882086.SacxiDRAFT_1513	2.672e-45	173.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4DY8H@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SRR25158512_k127_140232_0	42256.RradSPS_0916	7.201e-209	661.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CPP3@84995|Rubrobacteria	84995|Rubrobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158512_k127_140232_6	1283299.AUKG01000002_gene4955	1.095e-17	90.0	COG2931@1|root,COG2931@2|Bacteria,2HENU@201174|Actinobacteria,4CRGG@84995|Rubrobacteria	84995|Rubrobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_1404458_0	266117.Rxyl_2946	2.106e-111	380.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158512_k127_1404458_1	1239962.C943_03877	5.552e-29	128.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
SRR25158512_k127_1412151_4	42256.RradSPS_1574	2.084e-23	102.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CPGB@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158512_k127_1412151_3	266117.Rxyl_1632	4.899e-79	266.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CQ8D@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158512_k127_1412151_0	266117.Rxyl_1631	4.545e-213	666.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CP64@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158512_k127_1412151_1	42256.RradSPS_1571	3.546e-170	538.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CQ5K@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158512_k127_1412151_2	266117.Rxyl_1197	4.215e-85	284.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CQRQ@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158512_k127_1421_0	485913.Krac_0986	1.617e-186	594.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
SRR25158512_k127_1421_1	497964.CfE428DRAFT_0631	4.927e-171	570.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158512_k127_1421_6	926554.KI912673_gene2804	1.671e-20	102.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158512_k127_1421_7	1122611.KB903950_gene6347	2.304e-13	77.0	2ARZJ@1|root,31HBP@2|Bacteria,2I24G@201174|Actinobacteria,4EQEV@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1421_5	710685.MycrhN_2535	1.687e-23	113.0	COG2274@1|root,COG2274@2|Bacteria,2GNB5@201174|Actinobacteria,238WK@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158512_k127_1421_4	269797.Mbar_A2413	1.321e-34	139.0	COG3247@1|root,arCOG03582@2157|Archaea,2Y72H@28890|Euryarchaeota,2NB6I@224756|Methanomicrobia	224756|Methanomicrobia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158512_k127_1421_2	1439940.BAY1663_00503	8.92e-54	200.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158512_k127_1421_3	189425.PGRAT_31380	1.549e-48	183.0	COG4760@1|root,COG4760@2|Bacteria,1TQ9Z@1239|Firmicutes,4HEPV@91061|Bacilli,26SQG@186822|Paenibacillaceae	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
SRR25158512_k127_1423760_2	1157637.KB892124_gene577	6.502e-53	198.0	COG0500@1|root,COG0500@2|Bacteria,2I3FS@201174|Actinobacteria	201174|Actinobacteria	Q	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158512_k127_1423760_1	1713.JOFV01000003_gene1640	1.52e-116	389.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4F23K@85016|Cellulomonadaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158512_k127_1423760_0	42256.RradSPS_0731	9.311e-126	413.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4CQ0Z@84995|Rubrobacteria	84995|Rubrobacteria	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158512_k127_1423760_3	266117.Rxyl_0845	1.501e-48	174.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4CSU8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158512_k127_143616_3	1384056.N787_09940	2.186e-49	181.0	COG1247@1|root,COG1247@2|Bacteria,1QUGY@1224|Proteobacteria,1T1YJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yhhY	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158512_k127_143616_0	266117.Rxyl_2760	7.676e-160	509.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4CPGH@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_143616_2	745776.DGo_CA1289	8.861e-58	205.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_143616_1	266117.Rxyl_2759	4.57e-106	355.0	COG2128@1|root,COG2128@2|Bacteria,2GM9D@201174|Actinobacteria,4CTV7@84995|Rubrobacteria	84995|Rubrobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158512_k127_143616_4	861299.J421_4022	1.225e-48	178.0	COG2072@1|root,COG2072@2|Bacteria,1ZV84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1438196_2	266117.Rxyl_1983	9.137e-38	144.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria,4CPAR@84995|Rubrobacteria	84995|Rubrobacteria	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158512_k127_1438196_0	266117.Rxyl_1982	1.526e-243	766.0	COG3276@1|root,COG3276@2|Bacteria,2GKF9@201174|Actinobacteria,4CPDU@84995|Rubrobacteria	84995|Rubrobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_3
SRR25158512_k127_1438196_1	266117.Rxyl_1981	5.447e-60	211.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CSG6@84995|Rubrobacteria	84995|Rubrobacteria	H	MoaC family	-	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158512_k127_1458082_0	266117.Rxyl_0584	7.982e-205	644.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4CPN7@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158512_k127_1458082_1	266117.Rxyl_2933	3.638e-83	285.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria	201174|Actinobacteria	S	CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158512_k127_1458602_4	717605.Theco_3636	4.605e-19	98.0	COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4HF4M@91061|Bacilli,26R95@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158512_k127_1458602_0	525904.Tter_1921	1.966e-36	147.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158512_k127_1458602_1	1041159.AZUW01000017_gene2190	2.596e-34	143.0	2E3VP@1|root,32YSV@2|Bacteria,1RFZF@1224|Proteobacteria,2UFT8@28211|Alphaproteobacteria,4BK77@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1458602_5	251221.35211983	1.043e-06	60.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158512_k127_1458602_2	251221.35212996	4.912e-32	129.0	COG1695@1|root,COG1695@2|Bacteria,1GFIS@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_1458602_3	42256.RradSPS_3040	5.554e-26	108.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158512_k127_1466390_2	1169144.KB910948_gene3637	9.502e-28	116.0	COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,1ZBZP@1386|Bacillus	91061|Bacilli	S	ABC transporter	expZ	-	-	ko:K18231	ko02010,map02010	-	-	-	br01600,ko00000,ko00001,ko01504,ko02000	3.A.1.121.1,3.A.1.121.3	-	-	ABC_tran,ABC_tran_Xtn
SRR25158512_k127_1466390_1	266117.Rxyl_2891	3.007e-161	520.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4CPCU@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158512_k127_1466390_0	1283299.AUKG01000003_gene370	9.431e-183	582.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CP6T@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Malic_M,THF_DHG_CYH_C,malic
SRR25158512_k127_1489270_2	1173026.Glo7428_1727	5.374e-64	234.0	COG4292@1|root,COG4292@2|Bacteria,1G40Y@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158512_k127_1489270_0	266117.Rxyl_2610	3.279e-97	321.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158512_k127_1489270_4	266117.Rxyl_0632	1.347e-07	57.0	2DFSU@1|root,2ZT0P@2|Bacteria	2|Bacteria	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
SRR25158512_k127_1489270_3	1394178.AWOO02000045_gene6382	2.079e-55	203.0	COG5446@1|root,COG5446@2|Bacteria,2H6Y9@201174|Actinobacteria,4EJB8@85012|Streptosporangiales	201174|Actinobacteria	S	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
SRR25158512_k127_1489270_1	266117.Rxyl_0634	2.612e-72	254.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4CPS0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
SRR25158512_k127_1490562_0	42256.RradSPS_0200	7.348e-66	231.0	COG0702@1|root,COG0702@2|Bacteria,2GKNN@201174|Actinobacteria,4CQA3@84995|Rubrobacteria	84995|Rubrobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158512_k127_1490820_2	42256.RradSPS_2898	4.745e-30	127.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CU3Z@84995|Rubrobacteria	84995|Rubrobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158512_k127_1490820_1	42256.RradSPS_2899	2.57e-88	296.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CQ1Q@84995|Rubrobacteria	84995|Rubrobacteria	T	Response regulator receiver	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_1490820_0	266117.Rxyl_0866	1.33e-231	730.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158512_k127_1490820_3	266117.Rxyl_0533	1.789e-23	101.0	COG2159@1|root,COG2159@2|Bacteria,2GNF3@201174|Actinobacteria,4CQMN@84995|Rubrobacteria	84995|Rubrobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158512_k127_1495268_7	1089544.KB912942_gene1411	7.062e-36	153.0	COG2931@1|root,COG2931@2|Bacteria,2GTWD@201174|Actinobacteria	201174|Actinobacteria	Q	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1495268_1	266117.Rxyl_2948	2.973e-205	644.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158512_k127_1495268_4	266117.Rxyl_2949	1.826e-111	363.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158512_k127_1495268_6	42256.RradSPS_0295	5.707e-94	311.0	COG2316@1|root,COG2316@2|Bacteria,2GSXZ@201174|Actinobacteria,4CQ0P@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158512_k127_1495268_2	266117.Rxyl_2952	2.775e-158	506.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CPG5@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158512_k127_1495268_3	266117.Rxyl_2953	5.299e-124	407.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria,4CU11@84995|Rubrobacteria	84995|Rubrobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158512_k127_1495268_5	266117.Rxyl_2954	5.84e-96	319.0	COG2802@1|root,COG2802@2|Bacteria,2HP4R@201174|Actinobacteria,4CQGD@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
SRR25158512_k127_1495268_0	42256.RradSPS_0290	6.849e-237	737.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SRR25158512_k127_1495268_9	266117.Rxyl_2956	1.459e-20	91.0	COG1290@1|root,COG1290@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
SRR25158512_k127_1498702_1	42256.RradSPS_1965	2e-206	647.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CP8Q@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
SRR25158512_k127_1498702_3	266117.Rxyl_2177	3.68e-160	512.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,4CPEN@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA integrity scanning protein DisA	-	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH_2
SRR25158512_k127_1498702_5	266117.Rxyl_2176	1.569e-85	289.0	COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CQE7@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158512_k127_1498702_6	266117.Rxyl_2175	1.978e-80	274.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4CQHT@84995|Rubrobacteria	84995|Rubrobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158512_k127_1498702_2	266117.Rxyl_2174	1.415e-179	575.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158512_k127_1498702_0	266117.Rxyl_2173	1.757e-222	697.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CP99@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158512_k127_1498702_4	266117.Rxyl_2172	1.634e-94	314.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CPWF@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158512_k127_1498702_7	266117.Rxyl_2171	8.924e-61	216.0	COG3688@1|root,COG3688@2|Bacteria	2|Bacteria	D	RNA-binding protein containing a PIN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_IV,GTP_EFTU,NYN_YacP
SRR25158512_k127_1499893_1	485913.Krac_3494	1.705e-73	250.0	COG1486@1|root,COG1486@2|Bacteria,2G5KA@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
SRR25158512_k127_1499893_2	349521.HCH_04790	2.828e-50	184.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,1S5YT@1236|Gammaproteobacteria,1XMGB@135619|Oceanospirillales	135619|Oceanospirillales	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158512_k127_1499893_0	1502852.FG94_00798	2.228e-147	476.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2VP98@28216|Betaproteobacteria,473TB@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Winged helix DNA-binding domain	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158512_k127_1499893_3	1906.SFRA_06100	4.526e-46	169.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158512_k127_1518061_0	266117.Rxyl_2773	7.07e-262	826.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CQFZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158512_k127_1518061_3	266117.Rxyl_2772	2.251e-56	199.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CQFF@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158512_k127_1518061_1	756067.MicvaDRAFT_2833	2.794e-68	243.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria,1HAYJ@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
SRR25158512_k127_1518061_2	266117.Rxyl_2771	2.333e-66	233.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4CTWQ@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158512_k127_1518061_4	42256.RradSPS_2414	1.861e-15	77.0	29ITM@1|root,305QZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1523828_0	266117.Rxyl_1089	3.916e-110	359.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4CPRW@84995|Rubrobacteria	84995|Rubrobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158512_k127_1523828_1	266117.Rxyl_1088	2.32e-76	267.0	COG3103@1|root,COG4991@2|Bacteria,2IA2V@201174|Actinobacteria	201174|Actinobacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1523828_2	266117.Rxyl_1087	1.694e-25	105.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158512_k127_1530701_3	266117.Rxyl_0551	4.438e-28	129.0	COG1028@1|root,COG1028@2|Bacteria,2GNM4@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158512_k127_1530701_0	266117.Rxyl_0552	2.657e-206	652.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,4CT8G@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM Mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158512_k127_1530701_1	266117.Rxyl_0553	2.001e-157	507.0	COG0826@1|root,COG0826@2|Bacteria,2GKAK@201174|Actinobacteria,4CSIM@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
SRR25158512_k127_1530701_2	266117.Rxyl_0554	2.354e-33	131.0	COG2186@1|root,COG2186@2|Bacteria,2GP3H@201174|Actinobacteria,4CQQC@84995|Rubrobacteria	84995|Rubrobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158512_k127_1531961_2	264732.Moth_0623	4.105e-54	217.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,42EXW@68295|Thermoanaerobacterales	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158512_k127_1531961_0	324057.Pjdr2_5636	1.868e-222	721.0	COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,26QIW@186822|Paenibacillaceae	91061|Bacilli	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158512_k127_1531961_1	42256.RradSPS_2744	6.886e-126	414.0	COG2197@1|root,COG2197@2|Bacteria,2GPKD@201174|Actinobacteria,4CQCW@84995|Rubrobacteria	84995|Rubrobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158512_k127_1540123_3	266117.Rxyl_1075	4.017e-110	365.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria	201174|Actinobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158512_k127_1540123_2	266117.Rxyl_1073	1.461e-117	384.0	COG2159@1|root,COG2159@2|Bacteria,2HJ7X@201174|Actinobacteria,4CPK2@84995|Rubrobacteria	84995|Rubrobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158512_k127_1540123_0	266117.Rxyl_1072	1.162e-206	649.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158512_k127_1540123_4	266117.Rxyl_1070	5.412e-78	263.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158512_k127_1540123_6	42256.RradSPS_1027	1.27e-43	167.0	COG3412@1|root,COG3412@2|Bacteria	2|Bacteria	S	phosphoenolpyruvate-glycerone phosphotransferase activity	dhaM	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man,PTS-HPr
SRR25158512_k127_1540123_5	266117.Rxyl_1067	2.989e-76	260.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4CQ9Y@84995|Rubrobacteria	84995|Rubrobacteria	S	Dihydroxyacetone kinase	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158512_k127_1540123_1	66377.JOBH01000012_gene4308	1.089e-131	433.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158512_k127_1542015_2	266117.Rxyl_2574	5.263e-105	347.0	COG0500@1|root,COG0500@2|Bacteria,2I2WB@201174|Actinobacteria,4CSS3@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_1542015_1	266117.Rxyl_2572	2.511e-123	398.0	COG1387@1|root,COG1387@2|Bacteria,2IR14@201174|Actinobacteria,4CQ7N@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidinol phosphate phosphatase, HisJ	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR25158512_k127_1542015_0	266117.Rxyl_2571	6.658e-128	411.0	COG2872@1|root,COG2872@2|Bacteria,2I8P6@201174|Actinobacteria,4CSZI@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM Threonyl alanyl tRNA synthetase, SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_SAD
SRR25158512_k127_1542838_2	1028800.RG540_PA00120	4.563e-43	167.0	COG0006@1|root,COG0006@2|Bacteria,1RENF@1224|Proteobacteria,2U7VA@28211|Alphaproteobacteria,4BC69@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158512_k127_1542838_0	997346.HMPREF9374_2991	8.913e-108	355.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,4HCWD@91061|Bacilli	91061|Bacilli	S	Belongs to the D-glutamate cyclase family	ycsI	-	-	-	-	-	-	-	-	-	-	-	DUF1445
SRR25158512_k127_1542838_1	1150599.MPHLEI_19090	1.395e-69	241.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,233BF@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158512_k127_1556683_1	266117.Rxyl_1257	2.297e-101	338.0	COG0697@1|root,COG0697@2|Bacteria,2I198@201174|Actinobacteria,4CQSW@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_1556683_0	42256.RradSPS_1262	5.468e-160	518.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the LDH MDH superfamily. LDH family	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158512_k127_1556683_2	266117.Rxyl_1291	1.172e-48	178.0	COG0778@1|root,COG0778@2|Bacteria,2HRX2@201174|Actinobacteria,4CU07@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158512_k127_1556683_3	487521.OCU_12010	2.971e-06	55.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,232IW@1762|Mycobacteriaceae	201174|Actinobacteria	L	HhH-GPD family	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158512_k127_1560414_1	42256.RradSPS_0641	2.582e-88	293.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CQ7J@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158512_k127_1560414_4	1463853.JOHW01000009_gene479	2.333e-18	98.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158512_k127_1560414_0	1415780.JPOG01000001_gene1457	1.814e-88	308.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,1RMFE@1236|Gammaproteobacteria,1X43J@135614|Xanthomonadales	135614|Xanthomonadales	I	Alpha beta hydrolase	cpo	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158512_k127_1560414_2	266117.Rxyl_0429	9.65e-45	165.0	COG4319@1|root,COG4319@2|Bacteria,2II14@201174|Actinobacteria,4CTN6@84995|Rubrobacteria	84995|Rubrobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_1560414_3	471852.Tcur_0550	2.652e-44	171.0	COG2227@1|root,COG2227@2|Bacteria,2I3C3@201174|Actinobacteria,4ER5A@85012|Streptosporangiales	201174|Actinobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_1587133_1	1068980.ARVW01000001_gene6674	1.947e-49	186.0	COG2320@1|root,COG2320@2|Bacteria,2ICDV@201174|Actinobacteria,4E3U7@85010|Pseudonocardiales	201174|Actinobacteria	Q	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB,Methyltransf_11
SRR25158512_k127_1587133_2	754252.PFREUD_04230	6.016e-09	66.0	2EKVV@1|root,33EJD@2|Bacteria,2GYGM@201174|Actinobacteria,4DW0T@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1587133_3	405948.SACE_4576	0.0001325	51.0	COG0662@1|root,COG0662@2|Bacteria,2IN75@201174|Actinobacteria,4E72Y@85010|Pseudonocardiales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_1587133_0	42256.RradSPS_0391	2.808e-115	379.0	COG1597@1|root,COG1597@2|Bacteria,2I8DY@201174|Actinobacteria,4CTH7@84995|Rubrobacteria	84995|Rubrobacteria	I	COG COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism General function prediction only	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158512_k127_1597200_1	266117.Rxyl_1018	2.086e-80	288.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4CQAA@84995|Rubrobacteria	84995|Rubrobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158512_k127_1597200_0	42256.RradSPS_0969	3.261e-147	481.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria	201174|Actinobacteria	T	HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158512_k127_1597200_2	266117.Rxyl_1016	2.852e-05	48.0	COG0477@1|root,COG2814@2|Bacteria,2ID9K@201174|Actinobacteria,4CQJG@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_1609106_2	485913.Krac_6991	9.522e-43	168.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158512_k127_1609106_0	485913.Krac_10552	1.264e-51	199.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_1609106_1	266117.Rxyl_2416	2.075e-47	171.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4CPWQ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158512_k127_1618318_0	266117.Rxyl_1606	2.766e-124	401.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CPHA@84995|Rubrobacteria	84995|Rubrobacteria	D	ATPases associated with a variety of cellular activities	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158512_k127_1618318_2	867903.ThesuDRAFT_02365	1.153e-36	150.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3WCIS@538999|Clostridiales incertae sedis	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158512_k127_1618318_1	266117.Rxyl_1604	5.547e-73	249.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CPE0@84995|Rubrobacteria	84995|Rubrobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158512_k127_1626984_0	266117.Rxyl_0055	2.229e-194	610.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria	201174|Actinobacteria	M	3-beta hydroxysteroid dehydrogenase isomerase	-	-	-	ko:K21793	ko00333,ko01130,map00333,map01130	M00838	R11663,R11666	-	ko00000,ko00001,ko00002	-	-	-	Epimerase
SRR25158512_k127_1626984_1	42256.RradSPS_0064	1.098e-86	293.0	COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CQA7@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158512_k127_1626984_2	266117.Rxyl_0052	1.18e-27	116.0	COG3429@1|root,COG3429@2|Bacteria,2HYJH@201174|Actinobacteria,4CPZH@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158512_k127_1627323_3	1077972.ARGLB_064_00320	6.538e-16	79.0	COG3591@1|root,COG3591@2|Bacteria,2I3KX@201174|Actinobacteria	201174|Actinobacteria	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158512_k127_1627323_0	266117.Rxyl_0537	9.301e-123	399.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CSYH@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158512_k127_1627323_1	266117.Rxyl_0538	3.37e-76	258.0	COG1917@1|root,COG1917@2|Bacteria,2IAI4@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
SRR25158512_k127_1627323_2	1297863.APJF01000013_gene4077	3.096e-30	122.0	COG0346@1|root,COG0346@2|Bacteria,1NHW0@1224|Proteobacteria,2U2UX@28211|Alphaproteobacteria,3JXY0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_162789_5	1444309.JAQG01000139_gene1521	2.181e-73	256.0	COG0454@1|root,COG0456@2|Bacteria,1VT74@1239|Firmicutes,4HVC5@91061|Bacilli,273W2@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_162789_7	485913.Krac_6021	3.765e-56	212.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_162789_0	42256.RradSPS_1055	0.0	1877.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CP98@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158512_k127_162789_9	266117.Rxyl_1094	4.475e-26	110.0	COG2331@1|root,COG2331@2|Bacteria,2HGE7@201174|Actinobacteria,4CQV7@84995|Rubrobacteria	84995|Rubrobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158512_k127_162789_6	1207076.ALAT01000204_gene1790	2.006e-60	216.0	COG1247@1|root,COG1247@2|Bacteria,1QU4K@1224|Proteobacteria,1T2Q1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_162789_2	266117.Rxyl_1092	2.74e-155	495.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CQ0I@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158512_k127_162789_1	42256.RradSPS_1049	1.746e-158	511.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CPTX@84995|Rubrobacteria	84995|Rubrobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158512_k127_162789_4	42256.RradSPS_1048	1.122e-100	346.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158512_k127_162789_3	42256.RradSPS_1047	9.26e-132	422.0	COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CRHN@84995|Rubrobacteria	84995|Rubrobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158512_k127_1638814_2	1128427.KB904821_gene1739	1.007e-35	152.0	COG1928@1|root,COG1928@2|Bacteria,1G2A9@1117|Cyanobacteria,1H730@1150|Oscillatoriales	1117|Cyanobacteria	O	Dolichyl-phosphate-mannose--protein O-mannosyl transferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
SRR25158512_k127_1638814_1	42256.RradSPS_0561	2.204e-70	241.0	COG2258@1|root,COG2258@2|Bacteria,2GRBQ@201174|Actinobacteria,4CQID@84995|Rubrobacteria	84995|Rubrobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158512_k127_1638814_0	266117.Rxyl_2411	6.847e-256	794.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158512_k127_1642832_3	864051.BurJ1DRAFT_3700	2.993e-55	215.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
SRR25158512_k127_1642832_0	266117.Rxyl_2946	5.77e-183	600.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158512_k127_1642832_1	266117.Rxyl_0094	1.753e-84	289.0	COG2197@1|root,COG2197@2|Bacteria,2IG2E@201174|Actinobacteria	201174|Actinobacteria	KT	COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_1642832_2	266117.Rxyl_0093	3.332e-77	271.0	COG0784@1|root,COG2202@1|root,COG4585@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CT8E@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HisKA_3,PAS_3,PAS_9,Response_reg
SRR25158512_k127_1647859_2	42256.RradSPS_2255	2.144e-36	144.0	COG1725@1|root,COG1725@2|Bacteria,2GVVP@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158512_k127_1647859_3	1034769.KB910518_gene4452	1.319e-09	68.0	2EIC0@1|root,33C3C@2|Bacteria,1VQBU@1239|Firmicutes,4HRBU@91061|Bacilli,26UTW@186822|Paenibacillaceae	91061|Bacilli	-	-	M1-756	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1647859_0	318424.EU78_07170	4.695e-161	517.0	COG4573@1|root,COG4573@2|Bacteria,2IAVH@201174|Actinobacteria,233B8@1762|Mycobacteriaceae	201174|Actinobacteria	G	Tagatose 6 phosphate kinase	-	-	-	ko:K16371	ko00052,ko01100,map00052,map01100	-	R01069	RC00438,RC00439	ko00000,ko00001	-	-	-	Tagatose_6_P_K
SRR25158512_k127_1647859_1	1394178.AWOO02000017_gene6776	1.338e-135	447.0	COG2222@1|root,COG2222@2|Bacteria,2GSJ8@201174|Actinobacteria	201174|Actinobacteria	M	sugar isomerase, AgaS	agaS	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K02082	-	-	-	-	ko00000,ko01000	-	-	-	SIS
SRR25158512_k127_1649469_5	266117.Rxyl_1796	1.021e-23	101.0	COG2212@1|root,COG2212@2|Bacteria,2GTPK@201174|Actinobacteria,4CTVY@84995|Rubrobacteria	84995|Rubrobacteria	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
SRR25158512_k127_1649469_4	266117.Rxyl_1795	7.589e-38	147.0	COG1320@1|root,COG1320@2|Bacteria,2HRRR@201174|Actinobacteria,4CTUG@84995|Rubrobacteria	84995|Rubrobacteria	P	Na H antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
SRR25158512_k127_1649469_2	266117.Rxyl_3141	5.212e-60	218.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_1649469_3	1173026.Glo7428_1980	9.801e-59	215.0	COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158512_k127_1649469_0	1122927.KB895421_gene3964	5.49e-131	428.0	COG3616@1|root,COG3616@2|Bacteria,1TSES@1239|Firmicutes,4HEN0@91061|Bacilli,26U1V@186822|Paenibacillaceae	91061|Bacilli	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158512_k127_1649469_1	1123023.JIAI01000001_gene7218	1.058e-93	316.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4E029@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158512_k127_1663646_2	1121377.KB906405_gene96	2.691e-57	205.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158512_k127_1663646_1	266117.Rxyl_0512	1.651e-58	214.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158512_k127_1663646_0	266117.Rxyl_0513	1.556e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4CQ62@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_1664080_2	42256.RradSPS_0530	4.437e-146	476.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CQCB@84995|Rubrobacteria	84995|Rubrobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158512_k127_1664080_5	42256.RradSPS_2522	1.595e-79	276.0	COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CQ6I@84995|Rubrobacteria	84995|Rubrobacteria	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158512_k127_1664080_1	42256.RradSPS_2521	4.106e-168	540.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4CS6S@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158512_k127_1664080_3	1385519.N801_15930	1.039e-118	397.0	COG0531@1|root,COG0531@2|Bacteria,2HEX5@201174|Actinobacteria,4FFAE@85021|Intrasporangiaceae	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158512_k127_1664080_7	110319.CF8_3104	1.344e-29	124.0	COG0589@1|root,COG0589@2|Bacteria,2IN58@201174|Actinobacteria,4DUX7@85009|Propionibacteriales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_1664080_4	266117.Rxyl_0503	4.685e-112	364.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158512_k127_1664080_0	42256.RradSPS_2515	2.623e-199	623.0	COG1522@1|root,COG1522@2|Bacteria,2IIXK@201174|Actinobacteria,4CPCF@84995|Rubrobacteria	84995|Rubrobacteria	K	AsnC-type helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
SRR25158512_k127_1664080_6	266117.Rxyl_0506	2.04e-68	240.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158512_k127_1664080_8	1536769.P40081_25605	9.638e-06	51.0	COG0329@1|root,COG0329@2|Bacteria,1V10S@1239|Firmicutes,4HGKS@91061|Bacilli,26R9X@186822|Paenibacillaceae	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	4.1.2.28,4.3.3.7	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01782,R10147	RC00307,RC00572,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158512_k127_1677228_5	42256.RradSPS_0202	9.225e-09	57.0	COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
SRR25158512_k127_1677228_4	266117.Rxyl_3167	8.292e-47	176.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158512_k127_1677228_3	485913.Krac_6021	5.138e-54	205.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_1677228_0	448385.sce6690	6.648e-110	367.0	COG3214@1|root,COG3214@2|Bacteria,1R9AI@1224|Proteobacteria,43400@68525|delta/epsilon subdivisions,2X4C8@28221|Deltaproteobacteria,2YYQU@29|Myxococcales	28221|Deltaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158512_k127_1677228_2	1172188.KB911824_gene3270	4.496e-77	265.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4FIZW@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_1677228_1	266117.Rxyl_3168	2.595e-105	348.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4CPWT@84995|Rubrobacteria	84995|Rubrobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158512_k127_1684296_13	316067.Geob_3326	1.73e-06	57.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Hemolysin-type calcium-binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,HCBP_related,He_PIG,HemolysinCabind,Peptidase_M91,VWA_2
SRR25158512_k127_1684296_1	266117.Rxyl_2639	1.415e-146	469.0	COG0643@1|root,COG0643@2|Bacteria,2GYN8@201174|Actinobacteria	201174|Actinobacteria	NT	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1684296_5	266117.Rxyl_2638	6.154e-83	280.0	2DTEV@1|root,33K20@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1684296_2	266117.Rxyl_2634	2.014e-123	401.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CS51@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158512_k127_1684296_9	1445613.JALM01000081_gene1019	1.635e-57	212.0	COG0596@1|root,COG0596@2|Bacteria,2HBDG@201174|Actinobacteria,4E3A5@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_1684296_7	42256.RradSPS_0375	3.393e-80	297.0	COG1351@1|root,COG1351@2|Bacteria,2HCNJ@201174|Actinobacteria,4CQKC@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR25158512_k127_1684296_0	266117.Rxyl_2630	4.432e-317	978.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CQ79@84995|Rubrobacteria	84995|Rubrobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
SRR25158512_k127_1684296_8	266117.Rxyl_2622	8.573e-61	213.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158512_k127_1684296_6	266117.Rxyl_2560	1.089e-80	273.0	COG1988@1|root,COG1988@2|Bacteria	2|Bacteria	NT	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
SRR25158512_k127_1684296_10	1089553.Tph_c21530	1.778e-35	143.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,42GMQ@68295|Thermoanaerobacterales	186801|Clostridia	H	SMART Metal-dependent phosphohydrolase, HD region	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
SRR25158512_k127_1684296_3	266117.Rxyl_2558	2.175e-115	376.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4CPMK@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158512_k127_1693770_0	861299.J421_4022	4.656e-156	495.0	COG2072@1|root,COG2072@2|Bacteria,1ZV84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1693770_1	1003195.SCAT_0389	4.809e-13	71.0	COG0607@1|root,COG0607@2|Bacteria,2IN5N@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158512_k127_1693770_2	298655.KI912266_gene4328	3.396e-06	49.0	COG0607@1|root,COG0607@2|Bacteria,2IN5N@201174|Actinobacteria,4EW3U@85013|Frankiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158512_k127_1694174_0	266117.Rxyl_1022	4.037e-193	611.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CS0G@84995|Rubrobacteria	84995|Rubrobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
SRR25158512_k127_1694174_2	1227497.C491_06458	8.363e-75	266.0	COG0596@1|root,arCOG01648@2157|Archaea,2XVUY@28890|Euryarchaeota,23TK4@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158512_k127_1694174_3	710421.Mycch_2295	5.45e-29	125.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,235H0@1762|Mycobacteriaceae	201174|Actinobacteria	S	peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158512_k127_1694174_1	997346.HMPREF9374_0774	5.951e-135	441.0	COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4HBJU@91061|Bacilli,27CK4@186824|Thermoactinomycetaceae	91061|Bacilli	S	Protein of unknown function (DUF819)	yjcL	-	-	-	-	-	-	-	-	-	-	-	DUF819
SRR25158512_k127_1717259_2	42256.RradSPS_0938	3.169e-35	136.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4CPQF@84995|Rubrobacteria	84995|Rubrobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_1717259_1	1246995.AFR_09060	1.048e-42	160.0	COG0454@1|root,COG0456@2|Bacteria,2INVM@201174|Actinobacteria,4DF64@85008|Micromonosporales	201174|Actinobacteria	K	FR47-like protein	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158512_k127_1717259_0	266117.Rxyl_0938	3.754e-155	495.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria,4CPG6@84995|Rubrobacteria	84995|Rubrobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_1717259_3	266117.Rxyl_0937	2.078e-21	95.0	COG0517@1|root,COG0517@2|Bacteria,2GSAR@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
SRR25158512_k127_1719040_0	266117.Rxyl_2612	3.233e-158	507.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4CRWF@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158512_k127_1719040_1	485913.Krac_9019	5.812e-70	243.0	COG2197@1|root,COG2197@2|Bacteria,2G6JC@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_1722081_2	266117.Rxyl_2095	5.246e-119	386.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CP6K@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158512_k127_1722081_3	42256.RradSPS_1880	5.977e-94	317.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4CPX3@84995|Rubrobacteria	84995|Rubrobacteria	EH	Glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158512_k127_1722081_0	266117.Rxyl_2097	1.885e-148	475.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CPC0@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158512_k127_1722081_1	42256.RradSPS_1883	9.93e-124	407.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CSXQ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158512_k127_1722081_4	42256.RradSPS_2170	5.246e-13	72.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K03322,ko:K09944	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Usp
SRR25158512_k127_1730389_3	266117.Rxyl_0849	1.872e-46	169.0	COG0360@1|root,COG0360@2|Bacteria,2HPGC@201174|Actinobacteria,4CQUW@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S6	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158512_k127_1730389_4	266117.Rxyl_0850	2.537e-32	126.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4CQW6@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158512_k127_1730389_1	266117.Rxyl_0851	1.207e-71	244.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CQHN@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158512_k127_1730389_0	266117.Rxyl_0852	1.571e-243	757.0	COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CPNU@84995|Rubrobacteria	84995|Rubrobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158512_k127_1730389_2	395961.Cyan7425_3716	5.885e-60	213.0	COG1225@1|root,COG1225@2|Bacteria,1G59X@1117|Cyanobacteria,3KI23@43988|Cyanothece	1117|Cyanobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158512_k127_1730389_5	266117.Rxyl_0853	1.216e-30	120.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4CP6Q@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_1742619_0	266117.Rxyl_1262	2.431e-194	610.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4CRP2@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158512_k127_1742619_2	926550.CLDAP_31470	3.056e-79	274.0	COG3643@1|root,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
SRR25158512_k127_1742619_5	1122962.AULH01000009_gene3872	4.251e-27	118.0	COG3613@1|root,COG3613@2|Bacteria,1NP01@1224|Proteobacteria,2UNIH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
SRR25158512_k127_1742619_1	266117.Rxyl_1263	1.265e-133	436.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria,4CPAW@84995|Rubrobacteria	84995|Rubrobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158512_k127_1742619_4	251221.35213713	1.053e-38	149.0	COG0454@1|root,COG0454@2|Bacteria,1GQ3E@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
SRR25158512_k127_1742619_3	266117.Rxyl_1264	3.769e-45	167.0	COG1620@1|root,COG1620@2|Bacteria,2GIUF@201174|Actinobacteria	201174|Actinobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
SRR25158512_k127_1760970_4	266117.Rxyl_1106	2.569e-16	85.0	COG2931@1|root,COG2931@2|Bacteria,2GXGK@201174|Actinobacteria,4CQN3@84995|Rubrobacteria	84995|Rubrobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_1760970_0	760568.Desku_1684	6.633e-202	649.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,260BN@186807|Peptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158512_k127_1760970_1	1123023.JIAI01000002_gene5036	2.413e-110	364.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_1760970_3	469383.Cwoe_3822	1.384e-59	211.0	COG2128@1|root,COG2128@2|Bacteria,2IFER@201174|Actinobacteria,4CU3Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158512_k127_1760970_2	266117.Rxyl_0325	5.132e-68	236.0	COG0329@1|root,COG0329@2|Bacteria,2GNI3@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158512_k127_176843_0	266117.Rxyl_0837	6.044e-179	565.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CU65@84995|Rubrobacteria	84995|Rubrobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158512_k127_176843_1	42256.RradSPS_0727	8.2e-48	179.0	2BX8M@1|root,31H0R@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
SRR25158512_k127_1768932_6	1341151.ASZU01000006_gene2893	4.063e-19	94.0	COG2755@1|root,COG2755@2|Bacteria,1VAXZ@1239|Firmicutes,4HNDB@91061|Bacilli	91061|Bacilli	E	Lysophospholipase L1 and related esterases	ycsK	GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0044238,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158512_k127_1768932_0	1449063.JMLS01000001_gene4625	4.479e-118	393.0	COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli,26RMY@186822|Paenibacillaceae	91061|Bacilli	P	transporter	yycB	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
SRR25158512_k127_1768932_1	211114.JOEF01000023_gene5794	7.344e-60	217.0	COG0010@1|root,COG0010@2|Bacteria,2HG7A@201174|Actinobacteria,4EC0H@85010|Pseudonocardiales	201174|Actinobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR25158512_k127_1768932_4	485913.Krac_1745	4.205e-55	202.0	COG3340@1|root,COG3340@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158512_k127_1768932_2	525904.Tter_2769	1.08e-57	206.0	COG0262@1|root,COG0262@2|Bacteria,2NRFC@2323|unclassified Bacteria	2|Bacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1768932_3	593750.Metfor_2797	5.613e-56	201.0	COG3832@1|root,arCOG09481@1|root,arCOG05261@2157|Archaea,arCOG09481@2157|Archaea,2XYEH@28890|Euryarchaeota,2NAYB@224756|Methanomicrobia	224756|Methanomicrobia	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158512_k127_1768932_5	876269.ARWA01000001_gene3593	5.58e-45	165.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,3NCZX@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158512_k127_1768932_7	42256.RradSPS_0262	4.361e-09	60.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4CPJF@84995|Rubrobacteria	84995|Rubrobacteria	O	Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158512_k127_1825980_4	211114.JOEF01000037_gene6895	8.292e-18	85.0	2C5ZT@1|root,32RGE@2|Bacteria,2IM6T@201174|Actinobacteria,4E80R@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1825980_2	42256.RradSPS_2834	4.573e-41	159.0	2E5KE@1|root,3220Q@2|Bacteria,2HRSC@201174|Actinobacteria,4CTVE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1825980_0	1382306.JNIM01000001_gene1170	4.895e-147	477.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_1825980_3	42256.RradSPS_0273	6.363e-27	112.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158512_k127_1825980_1	266117.Rxyl_1713	7.701e-124	406.0	COG1597@1|root,COG1597@2|Bacteria,2I8DY@201174|Actinobacteria,4CTH7@84995|Rubrobacteria	84995|Rubrobacteria	I	COG COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism General function prediction only	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158512_k127_1826502_4	42256.RradSPS_1966	1.687e-12	67.0	2BCFA@1|root,3260X@2|Bacteria,2HBC1@201174|Actinobacteria,4CT3V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158512_k127_1826502_2	1274374.CBLK010000066_gene1530	4.075e-32	131.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli,26YI1@186822|Paenibacillaceae	91061|Bacilli	K	(GNAT) family	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_1826502_0	266117.Rxyl_1518	1.011e-123	403.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158512_k127_1826502_1	1283283.ATXA01000008_gene2989	1.667e-99	335.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_1826502_3	314278.NB231_06900	2.051e-29	117.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria,1S1BV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_1827383_0	266117.Rxyl_2048	9.858e-258	803.0	COG0591@1|root,COG0591@2|Bacteria,2GKPW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158512_k127_1827383_1	196162.Noca_0658	9.224e-118	385.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4DPHZ@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_1827383_2	266117.Rxyl_2051	9.566e-102	335.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	2|Bacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158512_k127_1831803_0	266117.Rxyl_1100	5.781e-87	294.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CU43@84995|Rubrobacteria	84995|Rubrobacteria	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
SRR25158512_k127_1831803_2	1380390.JIAT01000009_gene1192	4.304e-17	88.0	2FHCG@1|root,3496S@2|Bacteria,2H7A4@201174|Actinobacteria,4CQPX@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SRR25158512_k127_1831803_1	1429851.X548_16795	3.243e-67	235.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,1S2K3@1236|Gammaproteobacteria,1X9KM@135614|Xanthomonadales	135614|Xanthomonadales	O	glutathione s-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
SRR25158512_k127_1840637_12	663610.JQKO01000001_gene1035	2.958e-26	110.0	COG0151@1|root,COG0151@2|Bacteria,1R88F@1224|Proteobacteria,2U48H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the GarS family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1840637_2	1205680.CAKO01000006_gene3457	1.827e-101	342.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2JPA3@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
SRR25158512_k127_1840637_4	395965.Msil_0649	3.78e-86	293.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U1B8@28211|Alphaproteobacteria,3NBQ4@45404|Beijerinckiaceae	28211|Alphaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
SRR25158512_k127_1840637_0	937777.Deipe_3531	0.0	1022.0	COG1217@1|root,COG1217@2|Bacteria,1WINQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158512_k127_1840637_6	1307436.PBF_14619	2.049e-67	240.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus	91061|Bacilli	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SRR25158512_k127_1840637_11	1120983.KB894570_gene1747	1.122e-46	179.0	2CMKX@1|root,32SF3@2|Bacteria,1R4F1@1224|Proteobacteria,2U3NP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
SRR25158512_k127_1840637_3	443152.MDG893_16782	1.394e-93	313.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,1RMKM@1236|Gammaproteobacteria,464HP@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG4221 Short-chain alcohol dehydrogenase of	VY92_08700	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_1840637_5	570268.ANBB01000008_gene4759	7.536e-81	284.0	COG0477@1|root,COG2814@2|Bacteria,2GMWE@201174|Actinobacteria,4EJ8P@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_1840637_8	626887.J057_16395	3.646e-55	199.0	COG0454@1|root,COG0456@2|Bacteria,1RIAQ@1224|Proteobacteria,1T12P@1236|Gammaproteobacteria,46BCK@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_1840637_10	1183438.GKIL_0131	2.777e-49	179.0	COG3791@1|root,COG3791@2|Bacteria	2|Bacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158512_k127_1840637_1	485913.Krac_9072	4.003e-104	349.0	COG3214@1|root,COG3214@2|Bacteria,2G766@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158512_k127_1840637_7	1246995.AFR_02375	5.86e-56	199.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4DFRP@85008|Micromonosporales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_1840637_9	1206744.BAGL01000055_gene1585	1.834e-54	197.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4FX0D@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	yqjI	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_1846088_6	266117.Rxyl_0861	5.001e-13	74.0	COG3437@1|root,COG3437@2|Bacteria,2I49F@201174|Actinobacteria	201174|Actinobacteria	T	HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
SRR25158512_k127_1846088_4	42256.RradSPS_0688	3.714e-42	162.0	COG0454@1|root,COG0456@2|Bacteria,2HPAC@201174|Actinobacteria,4CQNP@84995|Rubrobacteria	84995|Rubrobacteria	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158512_k127_1846088_1	266117.Rxyl_0810	1.25e-86	293.0	COG1214@1|root,COG1214@2|Bacteria,2HP59@201174|Actinobacteria,4CQH7@84995|Rubrobacteria	84995|Rubrobacteria	O	Glycoprotease family	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SRR25158512_k127_1846088_3	266117.Rxyl_0809	1.144e-53	192.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CQQP@84995|Rubrobacteria	84995|Rubrobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158512_k127_1846088_0	266117.Rxyl_0808	2.583e-104	341.0	COG1573@1|root,COG1573@2|Bacteria,2GMPT@201174|Actinobacteria,4CQC2@84995|Rubrobacteria	84995|Rubrobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158512_k127_1846088_5	266117.Rxyl_0807	1.407e-20	92.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
SRR25158512_k127_1846088_2	266117.Rxyl_0804	8.491e-71	242.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CP9P@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158512_k127_1847218_6	266117.Rxyl_1106	1.425e-05	47.0	COG2931@1|root,COG2931@2|Bacteria,2GXGK@201174|Actinobacteria,4CQN3@84995|Rubrobacteria	84995|Rubrobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_1847218_0	42256.RradSPS_0097	2.106e-100	333.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	Peptidase_M23,PspA_IM30
SRR25158512_k127_1847218_4	266117.Rxyl_0335	3.097e-29	120.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	DnaJ,KTSC
SRR25158512_k127_185211_6	42256.RradSPS_2119	8.684e-31	123.0	COG0438@1|root,COG0500@1|root,COG0438@2|Bacteria,COG0500@2|Bacteria,2I2WB@201174|Actinobacteria,4CSS3@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_185211_1	266117.Rxyl_2575	6.273e-98	331.0	COG0438@1|root,COG0438@2|Bacteria,2GYA2@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158512_k127_185211_4	266117.Rxyl_2576	5.495e-55	195.0	COG0720@1|root,COG0720@2|Bacteria,2II5D@201174|Actinobacteria	201174|Actinobacteria	H	6-pyruvoyl tetrahydropterin synthase	ptpS	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158512_k127_185211_0	266117.Rxyl_2577	3.106e-115	381.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
SRR25158512_k127_185211_2	42256.RradSPS_2122	4.442e-86	295.0	COG1985@1|root,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribG	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158512_k127_185211_3	1111479.AXAR01000005_gene575	1.901e-72	250.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,2784U@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
SRR25158512_k127_185211_5	266117.Rxyl_2579	1.503e-48	179.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158512_k127_185700_4	42256.RradSPS_0665	6.176e-92	310.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4CPVH@84995|Rubrobacteria	84995|Rubrobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158512_k127_185700_5	42256.RradSPS_0210	6.243e-62	218.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4CQCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158512_k127_185700_3	1128421.JAGA01000002_gene336	3.63e-100	353.0	COG1807@1|root,COG1807@2|Bacteria,2NS23@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
SRR25158512_k127_185700_0	42256.RradSPS_0154	2.033e-204	650.0	COG0330@1|root,COG0330@2|Bacteria,2I8ZD@201174|Actinobacteria	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158512_k127_185700_1	42256.RradSPS_0155	2.002e-191	608.0	COG0330@1|root,COG0330@2|Bacteria,2GNWU@201174|Actinobacteria	201174|Actinobacteria	O	Membrane protease subunits, stomatin prohibitin	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158512_k127_185700_2	266117.Rxyl_3023	2.111e-151	487.0	COG1171@1|root,COG1171@2|Bacteria,2I8ZW@201174|Actinobacteria,4CQ5T@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
SRR25158512_k127_185700_6	266117.Rxyl_3131	9.809e-31	121.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CPIA@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158512_k127_1860185_0	42256.RradSPS_0839	2.795e-284	886.0	COG0531@1|root,COG0531@2|Bacteria,2GM81@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1860185_1	266117.Rxyl_1273	1.113e-74	258.0	COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria	201174|Actinobacteria	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158512_k127_1860185_2	266117.Rxyl_1272	3.234e-10	61.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CQH1@84995|Rubrobacteria	84995|Rubrobacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158512_k127_1866018_3	754035.Mesau_00142	4.339e-11	70.0	COG4319@1|root,COG4319@2|Bacteria,1NX6E@1224|Proteobacteria,2USZB@28211|Alphaproteobacteria,43PCQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_1866018_0	266117.Rxyl_2946	5.459e-174	572.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158512_k127_1866018_1	263358.VAB18032_24305	2.115e-39	162.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4DGTB@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_1866018_2	485913.Krac_2926	9.343e-24	105.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
SRR25158512_k127_1867569_1	42256.RradSPS_0951	2.055e-150	486.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4CQPJ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRR25158512_k127_1867569_2	266117.Rxyl_1083	1.043e-143	459.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158512_k127_1867569_6	42256.RradSPS_0953	2.005e-31	128.0	294QG@1|root,2ZS3T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1867569_0	266117.Rxyl_1081	2.501e-216	676.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,4CPV9@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158512_k127_1867569_4	56107.Cylst_0137	3.577e-73	255.0	COG1225@1|root,COG1225@2|Bacteria,1GJ4M@1117|Cyanobacteria,1HQDP@1161|Nostocales	1117|Cyanobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRR25158512_k127_1867569_3	266117.Rxyl_1079	2.112e-129	419.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,HAD,HAD_2,Hydrolase_like,NAD_synthase
SRR25158512_k127_1867569_5	42256.RradSPS_1038	2.494e-49	183.0	COG2839@1|root,COG2839@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF456)	yqgC	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
SRR25158512_k127_1874079_4	266117.Rxyl_3178	2.19e-46	171.0	COG1164@1|root,COG1164@2|Bacteria,2HDPQ@201174|Actinobacteria,4CTTS@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
SRR25158512_k127_1874079_2	266117.Rxyl_3177	7.919e-91	306.0	COG0484@1|root,COG0484@2|Bacteria,2I9V9@201174|Actinobacteria	201174|Actinobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,NERD
SRR25158512_k127_1874079_0	266117.Rxyl_3176	2.862e-196	617.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT,HEAT_2
SRR25158512_k127_1874079_1	1121423.JONT01000005_gene2608	4.062e-98	328.0	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,247ZD@186801|Clostridia	186801|Clostridia	S	Phenazine biosynthesis protein, PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SRR25158512_k127_187479_1	42256.RradSPS_2081	4.303e-154	488.0	COG0491@1|root,COG0491@2|Bacteria,2IB2K@201174|Actinobacteria,4CQK5@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158512_k127_187479_0	266117.Rxyl_2381	2.313e-227	709.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CPCX@84995|Rubrobacteria	84995|Rubrobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158512_k127_1875340_1	1132509.C447_09085	1.366e-151	487.0	COG0451@1|root,arCOG03019@2157|Archaea,2XVZH@28890|Euryarchaeota,23U95@183963|Halobacteria	183963|Halobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_1875340_0	266117.Rxyl_0536	4.55e-322	1004.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria	201174|Actinobacteria	G	D-galactarate dehydratase Altronate	-	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
SRR25158512_k127_1887499_0	266117.Rxyl_2590	1.369e-206	651.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria	201174|Actinobacteria	G	D-galactarate dehydratase Altronate	-	-	4.4.1.24	ko:K16846	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	GD_AH_C
SRR25158512_k127_1887499_3	266117.Rxyl_2591	1.059e-43	162.0	COG2721@1|root,COG2721@2|Bacteria,2GVET@201174|Actinobacteria	201174|Actinobacteria	G	SAF	-	-	4.4.1.24	ko:K16845	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	SAF
SRR25158512_k127_1887499_2	138119.DSY1502	2.229e-116	391.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158512_k127_1887499_1	545693.BMQ_3321	5.338e-159	515.0	COG0477@1|root,COG0477@2|Bacteria,1UHPS@1239|Firmicutes,4IS5K@91061|Bacilli,1ZS98@1386|Bacillus	91061|Bacilli	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_1890737_2	485913.Krac_3671	7.086e-68	234.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158512_k127_1890737_0	266117.Rxyl_0402	1.726e-241	759.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4CPEI@84995|Rubrobacteria	84995|Rubrobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_1890737_1	266117.Rxyl_0401	7.237e-184	580.0	COG1082@1|root,COG1082@2|Bacteria,2HRE6@201174|Actinobacteria,4CTCA@84995|Rubrobacteria	84995|Rubrobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158512_k127_1894385_2	266117.Rxyl_2981	8.696e-88	294.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158512_k127_1894385_0	266117.Rxyl_2979	2.036e-116	391.0	COG0628@1|root,COG0628@2|Bacteria,2HGG6@201174|Actinobacteria,4CQ8P@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158512_k127_1894385_3	266117.Rxyl_2978	1.719e-25	108.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158512_k127_1900811_1	1121377.KB906401_gene3526	1.138e-59	208.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158512_k127_1900811_3	1121920.AUAU01000003_gene1166	6.439e-25	107.0	COG0607@1|root,COG0607@2|Bacteria,3Y577@57723|Acidobacteria	57723|Acidobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158512_k127_1900811_2	42256.RradSPS_0965	6.824e-34	132.0	2E3DE@1|root,32YCK@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
SRR25158512_k127_1900811_0	1122915.AUGY01000033_gene925	4.683e-144	461.0	COG0667@1|root,COG0667@2|Bacteria,1TRHN@1239|Firmicutes,4H9ZV@91061|Bacilli,26RRE@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_1908239_3	1089545.KB913037_gene1139	7.614e-42	153.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria,4DY43@85010|Pseudonocardiales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158512_k127_1908239_8	266117.Rxyl_2315	2.965e-28	116.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Nitrile hydratase alpha	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
SRR25158512_k127_1908239_7	1089544.KB912942_gene1760	2.759e-32	132.0	2DMMA@1|root,32SDH@2|Bacteria,2IM8C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158512_k127_1908239_4	251229.Chro_2067	1.629e-34	136.0	2AFDI@1|root,315DC@2|Bacteria,1GKYE@1117|Cyanobacteria,3VNDC@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1908239_2	1333523.L593_08855	1.534e-48	184.0	arCOG12705@1|root,arCOG12705@2157|Archaea,2Y5BC@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1908239_1	266117.Rxyl_2315	5.022e-94	315.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Nitrile hydratase alpha	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
SRR25158512_k127_1908239_6	266117.Rxyl_2314	8.321e-34	134.0	2DBV6@1|root,32TY6@2|Bacteria	2|Bacteria	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
SRR25158512_k127_1908239_5	266117.Rxyl_2313	6.592e-34	132.0	2DSG6@1|root,33G0T@2|Bacteria	2|Bacteria	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
SRR25158512_k127_1908239_0	266117.Rxyl_2312	1.052e-164	523.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,4CQ4N@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase family 2	-	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR25158512_k127_1908239_9	266117.Rxyl_2311	4.887e-26	108.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4CQ4H@84995|Rubrobacteria	84995|Rubrobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158512_k127_1913050_1	266117.Rxyl_0101	3.696e-110	366.0	COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158512_k127_1913050_0	263358.VAB18032_03290	1.233e-138	452.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DEDW@85008|Micromonosporales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158512_k127_1913050_2	1128421.JAGA01000004_gene2687	2.448e-34	137.0	2AW22@1|root,31MWT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
SRR25158512_k127_1913050_3	42256.RradSPS_3059	4.456e-05	48.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CRZN@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_1913642_5	42256.RradSPS_0249	1.31e-18	86.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CU3Z@84995|Rubrobacteria	84995|Rubrobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158512_k127_1913642_4	1380347.JNII01000007_gene185	3.849e-19	91.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158512_k127_1913642_0	1120949.KB903326_gene3159	7.373e-88	298.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1913642_2	1123320.KB889686_gene587	4.223e-27	112.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria	201174|Actinobacteria	H	Dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1913642_3	1380370.JIBA01000010_gene2391	7.973e-25	107.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria,4FGXJ@85021|Intrasporangiaceae	201174|Actinobacteria	H	Dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_1913642_1	105422.BBPM01000060_gene4245	8.775e-32	125.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,2NIPJ@228398|Streptacidiphilus	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_1916344_0	479434.Sthe_2814	2.94e-185	590.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi,27YU8@189775|Thermomicrobia	189775|Thermomicrobia	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158512_k127_1916344_4	266117.Rxyl_2607	4.066e-75	262.0	COG0697@1|root,COG0697@2|Bacteria,2H1HG@201174|Actinobacteria,4CQ2H@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_1916344_2	243230.DR_1533	4.398e-106	353.0	COG3440@1|root,COG3440@2|Bacteria	2|Bacteria	V	regulation of methylation-dependent chromatin silencing	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH,HNH_2,SAD_SRA
SRR25158512_k127_1916344_5	1185876.BN8_02127	2.059e-46	172.0	2DMMQ@1|root,32SHK@2|Bacteria,4NSZY@976|Bacteroidetes,47RDZ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158512_k127_1916344_6	28042.GU90_10220	0.0001277	49.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4E13H@85010|Pseudonocardiales	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158512_k127_1916344_3	266117.Rxyl_0279	3.689e-89	297.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CQ8R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158512_k127_1916344_1	266117.Rxyl_0278	2.095e-111	361.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CPQW@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158512_k127_1920246_4	42256.RradSPS_1839	4.76e-46	168.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2IBPW@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158512_k127_1920246_1	42256.RradSPS_1838	1.206e-205	644.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CRJ5@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158512_k127_1920246_2	42256.RradSPS_2614	3.42e-150	479.0	COG2267@1|root,COG2267@2|Bacteria,2I4BW@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158512_k127_1920246_3	266117.Rxyl_1745	3.468e-113	377.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4CPAG@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158512_k127_1920246_0	42256.RradSPS_0358	1.464e-267	836.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158512_k127_1920520_0	266117.Rxyl_1168	8.264e-112	368.0	COG2309@1|root,COG2309@2|Bacteria,2INAN@201174|Actinobacteria,4CPAD@84995|Rubrobacteria	84995|Rubrobacteria	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158512_k127_1920520_1	42256.RradSPS_1157	1.445e-82	283.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158512_k127_1920520_2	266117.Rxyl_1153	1.394e-77	262.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158512_k127_1923650_0	1077972.ARGLB_058_00170	7e-259	806.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,1W860@1268|Micrococcaceae	201174|Actinobacteria	L	ABC transporter	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158512_k127_1923650_2	358823.DF19_13205	2.458e-72	245.0	COG0346@1|root,COG0346@2|Bacteria,2IHYP@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_1923650_1	1298880.AUEV01000020_gene533	2.161e-74	256.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158512_k127_1923650_4	42254.XP_004613832.1	1.595e-25	112.0	COG2453@1|root,KOG1720@2759|Eukaryota,3A0SJ@33154|Opisthokonta,3BQPQ@33208|Metazoa,3D771@33213|Bilateria,47ZA4@7711|Chordata,491DH@7742|Vertebrata,3J8HQ@40674|Mammalia	33208|Metazoa	V	protein tyrosine/serine/threonine phosphatase activity	DUSP23	GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031974,GO:0031981,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0140096,GO:1901564	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc
SRR25158512_k127_1923650_5	42256.RradSPS_2816	1.056e-24	116.0	2FCGD@1|root,344JU@2|Bacteria,2IRV1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_1923650_3	485913.Krac_10552	1.416e-42	165.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_193364_1	266117.Rxyl_1326	2.757e-138	456.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CPCE@84995|Rubrobacteria	84995|Rubrobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158512_k127_193364_2	266117.Rxyl_1327	2.41e-77	277.0	COG2514@1|root,COG2514@2|Bacteria,2HNS6@201174|Actinobacteria,4CPZV@84995|Rubrobacteria	84995|Rubrobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158512_k127_193364_0	1122138.AQUZ01000026_gene2950	5.194e-203	645.0	COG2234@1|root,COG2234@2|Bacteria,2GIT0@201174|Actinobacteria,4DUTG@85009|Propionibacteriales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
SRR25158512_k127_193661_1	402777.KB235903_gene1332	8.953e-63	220.0	COG1279@1|root,COG1279@2|Bacteria,1GQJ3@1117|Cyanobacteria,1HHX6@1150|Oscillatoriales	1117|Cyanobacteria	S	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158512_k127_193661_2	160799.PBOR_12675	2.704e-54	194.0	COG1522@1|root,COG1522@2|Bacteria,1V88V@1239|Firmicutes,4HJ89@91061|Bacilli,26YD7@186822|Paenibacillaceae	91061|Bacilli	K	AsnC family transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158512_k127_193661_0	266117.Rxyl_0176	9.449e-161	516.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158512_k127_1955071_0	266117.Rxyl_0005	3.762e-167	529.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CP8I@84995|Rubrobacteria	84995|Rubrobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158512_k127_1955071_1	266117.Rxyl_0004	1.003e-165	528.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CQ4U@84995|Rubrobacteria	84995|Rubrobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
SRR25158512_k127_1955071_3	42256.RradSPS_0003	5.042e-21	94.0	COG2501@1|root,COG2501@2|Bacteria	2|Bacteria	S	S4 domain	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
SRR25158512_k127_1955071_2	42256.RradSPS_0002	5.23e-157	500.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CP8Y@84995|Rubrobacteria	84995|Rubrobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158512_k127_1957819_4	266117.Rxyl_0021	1.07e-11	76.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158512_k127_1957819_2	42256.RradSPS_0842	4.794e-139	452.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone reductase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_1957819_1	42256.RradSPS_0841	9.365e-162	514.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria,4CSI0@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_1957819_0	266117.Rxyl_0720	5.968e-204	647.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4CPTK@84995|Rubrobacteria	84995|Rubrobacteria	E	Alcohol dehydrogenase GroES-associated	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158512_k127_1957819_3	42256.RradSPS_0938	4.802e-100	330.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4CPQF@84995|Rubrobacteria	84995|Rubrobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_1967879_0	1192034.CAP_1032	9.471e-62	226.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria	1224|Proteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158512_k127_1972613_3	266117.Rxyl_0601	3.259e-68	237.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	201174|Actinobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158512_k127_1972613_1	266117.Rxyl_0739	6.017e-107	354.0	COG0697@1|root,COG0697@2|Bacteria,2H1HG@201174|Actinobacteria,4CQ2H@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_1972613_0	266117.Rxyl_0738	3e-176	558.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158512_k127_1972613_2	266117.Rxyl_0737	3.046e-74	257.0	arCOG12117@1|root,2Z9N1@2|Bacteria,2GTM3@201174|Actinobacteria,4CU0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
SRR25158512_k127_1980883_10	266117.Rxyl_2856	7.452e-07	50.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158512_k127_1980883_7	309801.trd_1490	6.022e-19	93.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_1980883_1	266117.Rxyl_0484	1.685e-162	515.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4CPA4@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_1980883_3	42256.RradSPS_0474	7.314e-74	262.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria,4CQ7G@84995|Rubrobacteria	84995|Rubrobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158512_k127_1980883_0	42256.RradSPS_0473	2.989e-237	745.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4CPII@84995|Rubrobacteria	84995|Rubrobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158512_k127_1980883_2	42256.RradSPS_0472	1.786e-126	407.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4CPUB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158512_k127_1980883_8	266117.Rxyl_2733	9.066e-14	75.0	COG3448@1|root,COG3448@2|Bacteria,2IJXV@201174|Actinobacteria	201174|Actinobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
SRR25158512_k127_1980883_5	42256.RradSPS_2812	5.676e-51	183.0	COG4828@1|root,COG4828@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
SRR25158512_k127_1980883_4	289377.HL41_07305	6.766e-58	205.0	COG1620@1|root,COG1620@2|Bacteria,2GH8V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
SRR25158512_k127_198507_22	42256.RradSPS_1940	9.251e-45	162.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CPEQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158512_k127_198507_19	42256.RradSPS_1939	1.263e-51	183.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CQEC@84995|Rubrobacteria	84995|Rubrobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158512_k127_198507_20	266117.Rxyl_2150	1.669e-47	175.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4CQP9@84995|Rubrobacteria	84995|Rubrobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158512_k127_198507_2	42256.RradSPS_1937	1.362e-125	403.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CPWK@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158512_k127_198507_11	266117.Rxyl_2148	6.05e-78	261.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4CQ15@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158512_k127_198507_26	42256.RradSPS_1935	7.97e-24	102.0	COG0255@1|root,COG0255@2|Bacteria,2HPC6@201174|Actinobacteria,4CQQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158512_k127_198507_21	42256.RradSPS_1934	1.005e-45	171.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4CQJP@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158512_k127_198507_15	42256.RradSPS_1933	1.823e-64	221.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CQ56@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SRR25158512_k127_198507_24	883112.HMPREF9707_00198	6.072e-30	121.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,27E31@186827|Aerococcaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158512_k127_198507_7	266117.Rxyl_2143	1.47e-93	310.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158512_k127_198507_25	42256.RradSPS_1930	2.72e-29	117.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CQKA@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158512_k127_198507_14	266117.Rxyl_2141	1.253e-64	222.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4CQGZ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158512_k127_198507_10	266117.Rxyl_2140	2.612e-87	290.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CQ44@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158512_k127_198507_12	42256.RradSPS_1926	1.462e-71	252.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CPMN@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158512_k127_198507_27	42256.RradSPS_1925	6.169e-19	96.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4CQVX@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158512_k127_198507_16	42256.RradSPS_1924	2.669e-63	223.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CQD8@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158512_k127_198507_0	266117.Rxyl_2135	6.764e-208	654.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CPTT@84995|Rubrobacteria	84995|Rubrobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158512_k127_198507_9	266117.Rxyl_2134	2.512e-89	318.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CP9X@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158512_k127_198507_3	266117.Rxyl_2133	2.138e-122	399.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CPA2@84995|Rubrobacteria	84995|Rubrobacteria	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158512_k127_198507_23	266117.Rxyl_2132	1.419e-38	144.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4CQCQ@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158512_k127_198507_28	411474.COPEUT_02181	1.125e-13	70.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158512_k127_198507_17	42256.RradSPS_1918	7.04e-60	209.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4CQ8S@84995|Rubrobacteria	84995|Rubrobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158512_k127_198507_13	42256.RradSPS_1917	4.73e-69	235.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4CPZ7@84995|Rubrobacteria	84995|Rubrobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158512_k127_198507_4	42256.RradSPS_1916	1.577e-117	379.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CQ5S@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158512_k127_198507_1	266117.Rxyl_2128	3.79e-163	520.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CPU6@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158512_k127_198507_18	266117.Rxyl_2127	1.974e-58	205.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CQ5Q@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158512_k127_198507_6	266117.Rxyl_2126	2.938e-105	349.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria	201174|Actinobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158512_k127_198507_5	42256.RradSPS_1912	7.166e-107	363.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria	201174|Actinobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158512_k127_198507_8	266117.Rxyl_2124	5.655e-91	308.0	COG0619@1|root,COG0619@2|Bacteria,2INV1@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16783,ko:K16785	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158512_k127_2010518_1	1120950.KB892756_gene6642	2.739e-125	408.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4DPUK@85009|Propionibacteriales	201174|Actinobacteria	Q	Multicopper oxidase	cotA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158512_k127_2010518_4	1183438.GKIL_3443	0.0002418	49.0	2B3TF@1|root,31WH5@2|Bacteria,1G6YX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2010518_2	266117.Rxyl_0882	2.297e-43	172.0	COG2197@1|root,COG2197@2|Bacteria,2HEP2@201174|Actinobacteria,4CTV2@84995|Rubrobacteria	84995|Rubrobacteria	KT	regulatory protein, LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158512_k127_2010518_3	316274.Haur_1850	2.996e-32	141.0	COG3881@1|root,COG3881@2|Bacteria	2|Bacteria	S	PRC-barrel domain	yrrD	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158512_k127_2010518_0	266117.Rxyl_0436	7e-201	632.0	COG0589@1|root,COG1592@1|root,COG1773@1|root,COG0589@2|Bacteria,COG1592@2|Bacteria,COG1773@2|Bacteria	2|Bacteria	C	rubredoxin	hrb	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavin_Reduct,Lactamase_B,Rubredoxin,Rubrerythrin,Usp
SRR25158512_k127_2015829_4	272123.Anacy_5220	2.069e-27	128.0	COG2931@1|root,COG4625@1|root,COG2931@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.2.1.4	ko:K01179,ko:K07004	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Laminin_G_3,PATR
SRR25158512_k127_2015829_2	360910.BAV0730	3.059e-37	144.0	COG1917@1|root,COG1917@2|Bacteria,1RJBF@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
SRR25158512_k127_2015829_0	1380394.JADL01000011_gene3816	3.973e-83	283.0	COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,2TTKS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158512_k127_2015829_1	546414.Deide_02070	6.578e-51	182.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_2031598_2	266117.Rxyl_2697	1.208e-74	259.0	COG0457@1|root,COG0457@2|Bacteria	266117.Rxyl_2697|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2031598_5	266117.Rxyl_2696	8.293e-39	156.0	COG3944@1|root,COG3944@2|Bacteria	2|Bacteria	M	capsule polysaccharide biosynthetic process	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	GNVR,Wzz
SRR25158512_k127_2031598_4	266117.Rxyl_2695	1.803e-67	236.0	COG0489@1|root,COG0489@2|Bacteria	2|Bacteria	D	protein tyrosine kinase activity	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CBP_BcsQ
SRR25158512_k127_2031598_0	266117.Rxyl_2694	6.797e-187	598.0	COG3307@1|root,COG3307@2|Bacteria,2HQUG@201174|Actinobacteria,4CSM1@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158512_k127_2031598_1	1173026.Glo7428_0892	2.813e-95	323.0	28IVI@1|root,2Z8TY@2|Bacteria,1G87H@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
SRR25158512_k127_2031598_3	266117.Rxyl_2692	3.199e-72	261.0	COG0438@1|root,COG0438@2|Bacteria,2HUAV@201174|Actinobacteria,4CTZU@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158512_k127_2034800_5	82654.Pse7367_0932	6.665e-58	203.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1HB1V@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158512_k127_2034800_2	42256.RradSPS_0196	4.3e-320	1007.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria,4CPMZ@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158512_k127_2034800_3	266117.Rxyl_0318	4.789e-257	803.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4CPTF@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha amylase, catalytic domain	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158512_k127_2034800_1	519989.ECTPHS_06707	0.0	1053.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158512_k127_2034800_0	42256.RradSPS_0193	0.0	1086.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158512_k127_2034800_4	266117.Rxyl_0315	1.743e-96	322.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2GIV1@201174|Actinobacteria,4CPAY@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR25158512_k127_2041907_1	42256.RradSPS_1197	2.938e-24	104.0	COG2197@1|root,COG2197@2|Bacteria,2IG2E@201174|Actinobacteria	201174|Actinobacteria	KT	COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_2041907_0	266117.Rxyl_0303	8.489e-81	276.0	2EP7K@1|root,33GUA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_205106_1	266117.Rxyl_1482	9.5e-89	295.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158512_k127_205106_3	266117.Rxyl_1483	7.287e-78	274.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	divIVA	-	-	ko:K04074,ko:K06997	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
SRR25158512_k127_205106_4	42256.RradSPS_1491	2.374e-49	178.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158512_k127_205106_0	266117.Rxyl_1485	3.02e-112	368.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CQQG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158512_k127_205106_2	42256.RradSPS_1493	3.914e-83	279.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158512_k127_205106_5	1415780.JPOG01000001_gene981	3.505e-13	70.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,1S0IW@1236|Gammaproteobacteria,1X4SA@135614|Xanthomonadales	135614|Xanthomonadales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158512_k127_2058228_1	266117.Rxyl_1658	4.249e-126	408.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158512_k127_2058228_0	42256.RradSPS_2370	8.31e-159	520.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4CTMV@84995|Rubrobacteria	84995|Rubrobacteria	M	Capsule synthesis protein, CapA	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158512_k127_2058228_2	266117.Rxyl_1312	3.909e-46	172.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158512_k127_2062175_6	1869.MB27_35070	6.103e-09	63.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4DFMD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2062175_0	247156.NFA_32860	4.622e-54	194.0	COG4803@1|root,COG4803@2|Bacteria,2IHYU@201174|Actinobacteria,4G0I5@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158512_k127_2062175_7	426716.JOAJ01000001_gene198	8.94e-08	63.0	COG1280@1|root,COG1280@2|Bacteria,2HRC6@201174|Actinobacteria,4FYBP@85025|Nocardiaceae	201174|Actinobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158512_k127_2062175_2	338963.Pcar_3090	1.23e-50	195.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,43T6F@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158512_k127_2062175_1	1218352.B597_012185	7.33e-52	195.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria,1Z0RX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158512_k127_2062175_5	1437882.AZRU01000078_gene4012	6.198e-30	126.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria,1YIKM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158512_k127_2062175_4	1120949.KB903295_gene2534	9.139e-34	133.0	29JYD@1|root,306VN@2|Bacteria,2GWXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2062175_3	1156844.KB891831_gene4702	1.952e-43	164.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2065140_2	1246448.ANAZ01000019_gene967	1.936e-26	110.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_2065140_0	1169161.KB897721_gene4186	2.244e-179	575.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158512_k127_2065356_5	266117.Rxyl_3198	5.832e-55	196.0	COG2188@1|root,COG2188@2|Bacteria,2HPE1@201174|Actinobacteria,4CQS3@84995|Rubrobacteria	84995|Rubrobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158512_k127_2065356_2	42256.RradSPS_2752	1.033e-225	708.0	COG0833@1|root,COG0833@2|Bacteria,2GM7U@201174|Actinobacteria,4CRRR@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
SRR25158512_k127_2065356_0	266117.Rxyl_3196	2.666e-247	768.0	COG0174@1|root,COG0174@2|Bacteria,2GM3K@201174|Actinobacteria,4CPBS@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
SRR25158512_k127_2065356_1	42256.RradSPS_2749	8.892e-236	734.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPFP@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158512_k127_2065356_3	42256.RradSPS_2748	2.97e-132	426.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CPC2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_2065356_4	42256.RradSPS_2747	3.066e-72	245.0	COG0031@1|root,COG0031@2|Bacteria,2IEPQ@201174|Actinobacteria,4CT28@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent enzyme, beta subunit	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158512_k127_2069215_1	33876.JNXY01000012_gene4186	2.579e-52	186.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DAT6@85008|Micromonosporales	201174|Actinobacteria	E	ABC transporter, ATP-binding protein	-	-	3.6.3.21	ko:K02028,ko:K02029	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158512_k127_2069215_2	266117.Rxyl_0698	1.646e-40	159.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria,4CQE8@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158512_k127_2069215_0	1147.D082_25660	1.047e-82	302.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
SRR25158512_k127_2069215_3	1459636.NTE_00481	3.984e-25	115.0	arCOG03383@1|root,arCOG03383@2157|Archaea	2157|Archaea	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158512_k127_2070684_1	266117.Rxyl_0221	6.661e-68	233.0	COG0624@1|root,COG0624@2|Bacteria,2H2XC@201174|Actinobacteria,4CPHZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
SRR25158512_k127_2070684_0	266117.Rxyl_0220	1.077e-196	622.0	COG0160@1|root,COG0160@2|Bacteria,2GKVH@201174|Actinobacteria,4CRRI@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3
SRR25158512_k127_2070684_2	266117.Rxyl_0219	9.162e-64	220.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4CPS2@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158512_k127_2077899_1	1146883.BLASA_1057	6.502e-75	262.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EVZ3@85013|Frankiales	201174|Actinobacteria	T	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_2077899_0	1254432.SCE1572_02095	6.002e-195	623.0	COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales	28221|Deltaproteobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
SRR25158512_k127_2081038_0	42256.RradSPS_1781	1.068e-122	398.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CQ0V@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158512_k127_2081038_2	42256.RradSPS_1780	7.88e-29	116.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158512_k127_2081038_1	266117.Rxyl_1999	6.966e-32	128.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4CQHH@84995|Rubrobacteria	84995|Rubrobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158512_k127_2085402_6	1122915.AUGY01000016_gene2422	1.142e-06	56.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,4I26M@91061|Bacilli,2705Y@186822|Paenibacillaceae	91061|Bacilli	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_2085402_3	1121377.KB906421_gene3703	4.075e-44	168.0	2DM1Q@1|root,31BVP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2085402_4	266117.Rxyl_2611	9.626e-34	135.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_2085402_2	1122611.KB904007_gene7940	6.969e-55	196.0	COG0599@1|root,COG2021@1|root,COG0599@2|Bacteria,COG2021@2|Bacteria,2GITB@201174|Actinobacteria,4EIFT@85012|Streptosporangiales	201174|Actinobacteria	E	Carboxymuconolactone decarboxylase family	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,CMD
SRR25158512_k127_2085402_1	266117.Rxyl_1578	4.848e-98	329.0	COG2021@1|root,COG2021@2|Bacteria,2I36C@201174|Actinobacteria,4CQ4Y@84995|Rubrobacteria	84995|Rubrobacteria	E	Serine aminopeptidase, S33	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158512_k127_2085402_0	266117.Rxyl_1579	1.701e-180	577.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4CQ2M@84995|Rubrobacteria	84995|Rubrobacteria	F	Lyase	-	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158512_k127_2085402_5	1530186.JQEY01000017_gene248	2.971e-08	55.0	COG3485@1|root,COG3485@2|Bacteria,1MV3B@1224|Proteobacteria,2TTZJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protocatechuate 3,4-dioxygenase	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158512_k127_2088859_4	298654.FraEuI1c_3352	5.276e-15	80.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158512_k127_2088859_0	266117.Rxyl_0230	4.332e-264	824.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158512_k127_2088859_2	266117.Rxyl_0231	1.112e-97	324.0	COG0671@1|root,COG0671@2|Bacteria,2HRR1@201174|Actinobacteria,4CTTM@84995|Rubrobacteria	84995|Rubrobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158512_k127_2088859_1	266117.Rxyl_0232	5.864e-161	526.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2IE8G@201174|Actinobacteria,4CPJ4@84995|Rubrobacteria	84995|Rubrobacteria	I	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,SNARE_assoc
SRR25158512_k127_2088859_3	1121468.AUBR01000058_gene884	6.631e-57	204.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,24HX6@186801|Clostridia,42GCF@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158512_k127_2089753_4	266117.Rxyl_1363	1.584e-110	360.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158512_k127_2089753_3	266117.Rxyl_1364	4.153e-144	466.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,4CQ5P@84995|Rubrobacteria	84995|Rubrobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158512_k127_2089753_9	1464048.JNZS01000019_gene2327	1.776e-50	186.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4D8J2@85008|Micromonosporales	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158512_k127_2089753_1	266117.Rxyl_1366	3.001e-217	678.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,4CPH5@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158512_k127_2089753_7	266117.Rxyl_1367	1.313e-73	251.0	COG0054@1|root,COG0054@2|Bacteria,2II1Z@201174|Actinobacteria,4CQNG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158512_k127_2089753_12	42256.RradSPS_1374	3.01e-26	108.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4CQUE@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158512_k127_2089753_2	266117.Rxyl_1369	1.328e-204	649.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CPUZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158512_k127_2089753_11	743719.PaelaDRAFT_2490	2.204e-43	169.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158512_k127_2089753_0	266117.Rxyl_1371	0.0	1088.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CPM1@84995|Rubrobacteria	84995|Rubrobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158512_k127_2089753_8	266117.Rxyl_1372	2.035e-56	210.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CQ9U@84995|Rubrobacteria	84995|Rubrobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158512_k127_2089753_6	266117.Rxyl_1373	2.684e-74	262.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CQ3G@84995|Rubrobacteria	84995|Rubrobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158512_k127_2089753_5	42256.RradSPS_1380	2.012e-77	260.0	COG0711@1|root,COG0711@2|Bacteria,2HNZ4@201174|Actinobacteria,4CQ8B@84995|Rubrobacteria	84995|Rubrobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2089753_10	266117.Rxyl_1375	3.027e-49	184.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158512_k127_2099893_0	42256.RradSPS_3033	2.649e-100	330.0	COG0240@1|root,COG0240@2|Bacteria,2HYHZ@201174|Actinobacteria,4CQSG@84995|Rubrobacteria	84995|Rubrobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158512_k127_2099893_1	42256.RradSPS_1464	4.908e-98	323.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CPH7@84995|Rubrobacteria	84995|Rubrobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158512_k127_2099893_2	266117.Rxyl_1457	1.784e-33	131.0	COG0781@1|root,COG0781@2|Bacteria,2HP01@201174|Actinobacteria,4CQ9N@84995|Rubrobacteria	84995|Rubrobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158512_k127_2101013_1	42256.RradSPS_1010	1.299e-122	400.0	COG0346@1|root,COG0346@2|Bacteria,2IAYN@201174|Actinobacteria,4CQ41@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158512_k127_2101013_3	42256.RradSPS_1009	3.181e-78	279.0	COG0400@1|root,COG0400@2|Bacteria,2INMY@201174|Actinobacteria,4CTAJ@84995|Rubrobacteria	84995|Rubrobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	DLH
SRR25158512_k127_2101013_0	221288.JH992901_gene1078	3.701e-247	773.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1JHD5@1189|Stigonemataceae	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
SRR25158512_k127_2101013_2	251229.Chro_2182	1.309e-120	406.0	COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria,1G3MW@1117|Cyanobacteria,3VJ7X@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
SRR25158512_k127_2104490_7	266117.Rxyl_2651	7.748e-39	145.0	COG0555@1|root,COG0555@2|Bacteria,2I4C5@201174|Actinobacteria,4CQ7S@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158512_k127_2104490_9	266117.Rxyl_3207	4.885e-26	109.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4CQRP@84995|Rubrobacteria	84995|Rubrobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR,TOBE
SRR25158512_k127_2104490_8	42256.RradSPS_2627	1.446e-26	111.0	COG3835@1|root,COG3835@2|Bacteria	2|Bacteria	KT	positive regulation of transcription, DNA-templated	pucR_3	-	-	ko:K02647,ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,HTH_30,PucR,V4R,XylR_N
SRR25158512_k127_2104490_5	266117.Rxyl_0111	2.927e-74	252.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4CT01@84995|Rubrobacteria	84995|Rubrobacteria	C	2Fe-2S -binding	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158512_k127_2104490_0	266117.Rxyl_0112	0.0	1249.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CS94@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158512_k127_2104490_4	266117.Rxyl_0113	1.461e-122	398.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CSQX@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158512_k127_2104490_2	266117.Rxyl_0114	3.279e-155	495.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CQYG@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158512_k127_2104490_1	266117.Rxyl_0115	2.165e-161	517.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CRRF@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158512_k127_2104490_6	42256.RradSPS_2621	2.935e-52	188.0	COG1975@1|root,COG1975@2|Bacteria,2IJ4H@201174|Actinobacteria,4CTVX@84995|Rubrobacteria	84995|Rubrobacteria	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
SRR25158512_k127_2104490_3	266117.Rxyl_0117	1.104e-132	427.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4CQ5H@84995|Rubrobacteria	84995|Rubrobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158512_k127_2107130_0	266117.Rxyl_3186	1.031e-183	578.0	COG0403@1|root,COG0403@2|Bacteria,2IBH2@201174|Actinobacteria,4CP8Z@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158512_k127_2107130_2	1089553.Tph_c17190	7.981e-156	505.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,42FHX@68295|Thermoanaerobacterales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	GDC-P
SRR25158512_k127_2107130_1	42256.RradSPS_2741	8.649e-166	532.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CP79@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158512_k127_2107130_5	266117.Rxyl_3183	3.071e-52	188.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158512_k127_2107130_4	42256.RradSPS_2739	2.325e-101	336.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,4CPXC@84995|Rubrobacteria	84995|Rubrobacteria	K	TipAS antibiotic-recognition domain	-	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TipAS
SRR25158512_k127_2107130_3	266117.Rxyl_1794	6.32e-148	474.0	COG2514@1|root,COG2514@2|Bacteria,2GN1X@201174|Actinobacteria,4CPNZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158512_k127_2107130_6	1254432.SCE1572_04915	1.34e-12	71.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,4340C@68525|delta/epsilon subdivisions,2X4EB@28221|Deltaproteobacteria,2YYUY@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158512_k127_2107203_5	42256.RradSPS_0714	3.747e-86	287.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158512_k127_2107203_6	266117.Rxyl_0824	6.64e-67	236.0	COG3897@1|root,COG3897@2|Bacteria,2GTAU@201174|Actinobacteria,4CQPT@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
SRR25158512_k127_2107203_7	266117.Rxyl_0823	9.473e-67	229.0	COG1959@1|root,COG1959@2|Bacteria,2HNE1@201174|Actinobacteria,4CQQM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158512_k127_2107203_2	42256.RradSPS_0705	1.114e-97	323.0	COG0704@1|root,COG0704@2|Bacteria,2HGEG@201174|Actinobacteria,4CPTJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158512_k127_2107203_0	926550.CLDAP_00810	8.359e-108	356.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158512_k127_2107203_3	489825.LYNGBM3L_13010	1.185e-94	328.0	COG0581@1|root,COG0581@2|Bacteria,1G2GA@1117|Cyanobacteria,1H9A2@1150|Oscillatoriales	1117|Cyanobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158512_k127_2107203_1	251229.Chro_0130	4.848e-98	329.0	COG0573@1|root,COG0573@2|Bacteria,1G1JR@1117|Cyanobacteria,3VM00@52604|Pleurocapsales	1117|Cyanobacteria	U	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158512_k127_2107203_4	329726.AM1_0177	5.228e-87	299.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
SRR25158512_k127_210892_0	42256.RradSPS_1112	2.082e-193	606.0	COG0191@1|root,COG0191@2|Bacteria,2H640@201174|Actinobacteria,4CSJD@84995|Rubrobacteria	84995|Rubrobacteria	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158512_k127_210892_1	1123368.AUIS01000009_gene2443	1.013e-73	254.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158512_k127_210892_3	42256.RradSPS_1116	3.018e-42	161.0	COG3238@1|root,COG3238@2|Bacteria,2HQYP@201174|Actinobacteria,4CSRF@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
SRR25158512_k127_210892_2	266117.Rxyl_1122	9.887e-44	160.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CR10@84995|Rubrobacteria	84995|Rubrobacteria	H	May be involved in the biosynthesis of molybdopterin	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR25158512_k127_2109644_1	742727.HMPREF9447_02951	8.034e-84	283.0	COG3408@1|root,COG3408@2|Bacteria,4NI03@976|Bacteroidetes,2FQYR@200643|Bacteroidia,4AMVT@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
SRR25158512_k127_2109644_0	1128421.JAGA01000001_gene2184	2.282e-84	286.0	COG1082@1|root,COG1082@2|Bacteria,2NQSY@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	iolE	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158512_k127_2109644_2	1128421.JAGA01000001_gene2226	1.3e-33	132.0	COG0673@1|root,COG0673@2|Bacteria,2NQDT@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_2138802_1	479434.Sthe_2538	4.03e-77	274.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158512_k127_2138802_2	575540.Isop_1081	4.061e-05	51.0	COG0236@1|root,COG0236@2|Bacteria,2J1MP@203682|Planctomycetes	203682|Planctomycetes	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SRR25158512_k127_2138802_0	479434.Sthe_2541	1.031e-174	563.0	COG0318@1|root,COG0318@2|Bacteria,2G5XY@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158512_k127_2143592_0	42256.RradSPS_2571	3.997e-223	696.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,4CPFZ@84995|Rubrobacteria	84995|Rubrobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158512_k127_2143592_1	42256.RradSPS_2569	8.574e-155	491.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4CPKU@84995|Rubrobacteria	84995|Rubrobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11
SRR25158512_k127_2143592_3	42256.RradSPS_2568	8.757e-24	102.0	COG3301@1|root,COG3301@2|Bacteria,2GJ4S@201174|Actinobacteria	201174|Actinobacteria	P	reductase	nrfD	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158512_k127_2150376_0	266117.Rxyl_0944	5.305e-121	396.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,4CPAV@84995|Rubrobacteria	84995|Rubrobacteria	EH	PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate enzyme, central region thiamine pyrophosphate enzyme-like TPP binding region	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158512_k127_2150376_1	266117.Rxyl_0949	1.188e-117	385.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CQ0G@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158512_k127_215172_4	1283299.AUKG01000006_gene829	2.748e-11	72.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158512_k127_215172_1	266117.Rxyl_0980	6.301e-143	456.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158512_k127_215172_2	1089551.KE386572_gene1056	6.591e-118	399.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2TT27@28211|Alphaproteobacteria,4BS8X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_215172_0	266117.Rxyl_0585	5.789e-192	607.0	COG1228@1|root,COG1228@2|Bacteria,2GJH4@201174|Actinobacteria,4CQ30@84995|Rubrobacteria	84995|Rubrobacteria	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	-	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158512_k127_215172_5	926560.KE387025_gene4006	4.287e-07	53.0	COG0454@1|root,COG0456@2|Bacteria,1WMGT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_2155834_2	1157708.KB907450_gene5778	6.064e-32	128.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2VNYR@28216|Betaproteobacteria,4AJ6B@80864|Comamonadaceae	28216|Betaproteobacteria	P	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_2155834_4	1380390.JIAT01000010_gene4313	1.823e-08	63.0	COG5663@1|root,COG5663@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
SRR25158512_k127_2155834_0	266117.Rxyl_2210	9.114e-227	711.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4CSG9@84995|Rubrobacteria	84995|Rubrobacteria	P	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_2180976_0	42256.RradSPS_0812	0.0	1184.0	COG1429@1|root,COG1429@2|Bacteria,2GK0U@201174|Actinobacteria,4CPSC@84995|Rubrobacteria	84995|Rubrobacteria	H	CobN/Magnesium Chelatase	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
SRR25158512_k127_2190783_3	266117.Rxyl_2692	1.129e-56	203.0	COG0438@1|root,COG0438@2|Bacteria,2HUAV@201174|Actinobacteria,4CTZU@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158512_k127_2190783_2	266117.Rxyl_2691	2.286e-99	340.0	COG1922@1|root,COG1922@2|Bacteria,2ICDG@201174|Actinobacteria,4CSRD@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
SRR25158512_k127_2190783_0	42256.RradSPS_2335	1.306e-130	429.0	COG3271@1|root,COG3271@2|Bacteria,2GM3Z@201174|Actinobacteria	201174|Actinobacteria	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
SRR25158512_k127_2190783_4	65093.PCC7418_1860	7.645e-32	138.0	2E3N5@1|root,32YKB@2|Bacteria,1G9J7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2190783_1	42256.RradSPS_0459	1.391e-109	371.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CP93@84995|Rubrobacteria	84995|Rubrobacteria	GM	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158512_k127_2193730_2	42256.RradSPS_2439	7.217e-42	156.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4CQEK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158512_k127_2193730_1	266117.Rxyl_2794	1.872e-73	252.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4CQAK@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158512_k127_2193730_0	42256.RradSPS_2437	1.157e-75	258.0	COG3859@1|root,COG3859@2|Bacteria	2|Bacteria	S	thiamine transport	thiT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
SRR25158512_k127_2204351_2	42256.RradSPS_1889	9.04e-99	333.0	COG0477@1|root,COG2814@2|Bacteria,2HQMP@201174|Actinobacteria,4CS79@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_2204351_5	266117.Rxyl_0694	1.232e-23	100.0	COG0401@1|root,COG0401@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
SRR25158512_k127_2204351_1	266117.Rxyl_0300	6.767e-117	379.0	COG0625@1|root,COG0625@2|Bacteria,2HBBW@201174|Actinobacteria,4CT8I@84995|Rubrobacteria	84995|Rubrobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N,GST_N_3
SRR25158512_k127_2204351_0	42256.RradSPS_2086	1.185e-138	459.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
SRR25158512_k127_2204351_4	760568.Desku_3214	3.892e-44	170.0	COG5483@1|root,COG5483@2|Bacteria,1V4SJ@1239|Firmicutes,24A6M@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158512_k127_2204351_3	760568.Desku_3213	1.062e-52	191.0	COG5483@1|root,COG5483@2|Bacteria,1VA74@1239|Firmicutes,24PPB@186801|Clostridia,26608@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158512_k127_2208069_3	266117.Rxyl_0218	4.944e-61	213.0	COG0697@1|root,COG0697@2|Bacteria,2I9T9@201174|Actinobacteria	201174|Actinobacteria	EG	transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_2208069_0	42256.RradSPS_2686	1.79e-198	620.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4CQ61@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-dependent oxidoreductase, G6PDH family	-	-	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
SRR25158512_k127_2208069_1	266117.Rxyl_0216	1.758e-138	450.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4CTUU@84995|Rubrobacteria	84995|Rubrobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158512_k127_2208069_2	42256.RradSPS_2688	5.81e-69	239.0	COG1695@1|root,COG1695@2|Bacteria,2ISJ2@201174|Actinobacteria,4CST7@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158512_k127_2208069_6	42256.RradSPS_2349	5.049e-18	91.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
SRR25158512_k127_2208069_4	479432.Sros_5880	1.013e-26	117.0	2E5J0@1|root,330AB@2|Bacteria,2I805@201174|Actinobacteria,4ERAW@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2208069_5	1173026.Glo7428_2805	6.379e-24	103.0	2DKWS@1|root,30N64@2|Bacteria,1G5E4@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR25158512_k127_2214222_3	882082.SaccyDRAFT_4002	8.956e-38	143.0	2BVHN@1|root,332R2@2|Bacteria,2IPM7@201174|Actinobacteria,4EBJ7@85010|Pseudonocardiales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158512_k127_2214222_1	644283.Micau_4404	2.298e-108	357.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4DBPI@85008|Micromonosporales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158512_k127_2214222_0	42256.RradSPS_1836	4.696e-139	454.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4CSCW@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158512_k127_2214222_2	42256.RradSPS_0677	6.71e-68	239.0	28JXC@1|root,2Z9MV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
SRR25158512_k127_2232219_2	266117.Rxyl_3085	3.736e-52	195.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_2232219_1	266117.Rxyl_3141	6.561e-53	199.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_2232219_4	1120949.KB903295_gene2584	1.754e-24	111.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4DJCH@85008|Micromonosporales	201174|Actinobacteria	C	FMN binding	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158512_k127_2232219_3	266117.Rxyl_3072	2.645e-38	162.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_2232219_0	266117.Rxyl_3073	0.0	1280.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4CQHI@84995|Rubrobacteria	84995|Rubrobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158512_k127_2238276_1	272560.BPSS2072	4.042e-135	437.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2VPUK@28216|Betaproteobacteria,1K03P@119060|Burkholderiaceae	28216|Betaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158512_k127_2238276_0	1123321.KB905819_gene5962	3.414e-159	513.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158512_k127_2238276_2	1120950.KB892731_gene3826	3.992e-60	217.0	COG2186@1|root,COG2186@2|Bacteria,2IBVY@201174|Actinobacteria,4DUAK@85009|Propionibacteriales	201174|Actinobacteria	K	FCD	dgoR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158512_k127_2238276_3	1030157.AFMP01000031_gene3010	2.622e-50	192.0	COG1028@1|root,COG1028@2|Bacteria,1MWIJ@1224|Proteobacteria,2U290@28211|Alphaproteobacteria,2K35G@204457|Sphingomonadales	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378	ko:K00059,ko:K18337	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R03942,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10788,R10995,R11671	RC00029,RC00066,RC00117,RC00161	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_2238276_4	1122611.KB903943_gene1510	2.64e-47	173.0	COG2017@1|root,COG2017@2|Bacteria,2GU0M@201174|Actinobacteria,4EME4@85012|Streptosporangiales	201174|Actinobacteria	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim,DUF4432
SRR25158512_k127_2244224_5	102129.Lepto7375DRAFT_5776	1.776e-15	86.0	COG5094@1|root,COG5094@2|Bacteria,1G59D@1117|Cyanobacteria,1HANY@1150|Oscillatoriales	1117|Cyanobacteria	K	RNA polymerase II transcriptional preinitiation complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2244224_2	378806.STAUR_3208	6.689e-111	372.0	COG4715@1|root,COG4715@2|Bacteria,1R5NS@1224|Proteobacteria,42W30@68525|delta/epsilon subdivisions,2WRQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
SRR25158512_k127_2244224_1	266117.Rxyl_0631	5.527e-120	393.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100,1.1.1.69	ko:K00046,ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_2244224_0	42256.RradSPS_2227	9.89e-143	461.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158512_k127_2244224_4	1117108.PAALTS15_14461	4.101e-45	169.0	COG0457@1|root,COG0457@2|Bacteria,1V3U6@1239|Firmicutes,4HFWW@91061|Bacilli,26YEI@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_5,TPR_6,TPR_8
SRR25158512_k127_2244224_3	266117.Rxyl_0618	5.12e-99	325.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CPJQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158512_k127_2251193_1	42256.RradSPS_2007	1.567e-134	436.0	COG1233@1|root,COG1233@2|Bacteria,2I8A6@201174|Actinobacteria	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158512_k127_2251193_0	1242864.D187_005040	1.012e-142	472.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,42YS3@68525|delta/epsilon subdivisions,2WU59@28221|Deltaproteobacteria,2YTT1@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158512_k127_2251193_2	765420.OSCT_1132	2.831e-25	110.0	COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_2254825_0	324602.Caur_2809	5.094e-160	511.0	COG1064@1|root,COG1064@2|Bacteria,2G7SY@200795|Chloroflexi,376P5@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_2254825_1	266117.Rxyl_0447	1.013e-95	322.0	COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4CTIU@84995|Rubrobacteria	84995|Rubrobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Metallophos
SRR25158512_k127_2254825_3	1121946.AUAX01000002_gene40	8.817e-25	109.0	COG5485@1|root,COG5485@2|Bacteria,2HPCG@201174|Actinobacteria,4DGE1@85008|Micromonosporales	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158512_k127_2254825_5	1283299.AUKG01000001_gene3201	0.0009701	50.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158512_k127_2254825_2	268407.PWYN_22775	7.424e-60	211.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26TF8@186822|Paenibacillaceae	91061|Bacilli	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158512_k127_227447_2	266117.Rxyl_1150	2e-52	187.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	-
SRR25158512_k127_227447_3	42256.RradSPS_1152	1.176e-48	177.0	2B5Y2@1|root,31YU2@2|Bacteria,2H193@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_227447_0	42256.RradSPS_1153	2.266e-114	381.0	COG3380@1|root,COG3380@2|Bacteria,2IA89@201174|Actinobacteria	201174|Actinobacteria	S	NAD FAD-dependent oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158512_k127_227447_1	266117.Rxyl_1152	8.599e-93	309.0	COG0123@1|root,COG0123@2|Bacteria,2IDFT@201174|Actinobacteria,4CSQY@84995|Rubrobacteria	84995|Rubrobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158512_k127_227484_1	42256.RradSPS_2472	2.22e-130	428.0	COG0371@1|root,COG0371@2|Bacteria,2HRTP@201174|Actinobacteria,4CTX5@84995|Rubrobacteria	2|Bacteria	C	COG COG0371 Glycerol dehydrogenase and related enzymes Energy production and conversion	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
SRR25158512_k127_227484_2	266117.Rxyl_3007	3.44e-94	315.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CT7G@84995|Rubrobacteria	84995|Rubrobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_227484_0	42256.RradSPS_2473	3.385e-139	449.0	COG2390@1|root,COG2390@2|Bacteria,2GMIM@201174|Actinobacteria,4CTRB@84995|Rubrobacteria	84995|Rubrobacteria	K	COG COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain Transcription	-	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	MarR_2,Sugar-bind
SRR25158512_k127_227484_3	42256.RradSPS_2477	2.565e-80	271.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158512_k127_2277244_3	675635.Psed_6439	5.22e-15	78.0	COG0596@1|root,COG0596@2|Bacteria,2I320@201174|Actinobacteria,4EFEM@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_2277244_1	266117.Rxyl_1792	1.194e-75	259.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
SRR25158512_k127_2277244_0	266117.Rxyl_1793	6.436e-90	300.0	COG2085@1|root,COG2085@2|Bacteria,2I8W4@201174|Actinobacteria,4CQDF@84995|Rubrobacteria	84995|Rubrobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158512_k127_2277244_2	408672.NBCG_05438	5.78e-73	250.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4DREM@85009|Propionibacteriales	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
SRR25158512_k127_2297448_4	1382356.JQMP01000001_gene810	3.942e-10	60.0	COG0665@1|root,COG0665@2|Bacteria,2GBER@200795|Chloroflexi,27Z6Q@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158512_k127_2297448_1	1120950.KB892740_gene2579	7.813e-58	207.0	COG0702@1|root,COG0702@2|Bacteria,2I234@201174|Actinobacteria,4DUWN@85009|Propionibacteriales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158512_k127_2297448_3	1463934.JOCF01000003_gene2885	7.485e-25	116.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158512_k127_2297448_2	1120950.KB892740_gene2578	8.775e-54	196.0	COG1309@1|root,COG1309@2|Bacteria,2GKW3@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_2297448_0	266117.Rxyl_0219	1.055e-185	586.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4CPS2@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158512_k127_2300849_2	32057.KB217483_gene8843	5.807e-14	86.0	COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,1GPXH@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158512_k127_2300849_0	266117.Rxyl_2510	3.653e-118	407.0	COG0784@1|root,COG2202@1|root,COG4585@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158512_k127_2300849_1	42256.RradSPS_2103	1.128e-64	228.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CSY6@84995|Rubrobacteria	84995|Rubrobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_2303032_1	1120949.KB903317_gene1675	4.98e-12	76.0	COG2931@1|root,COG2931@2|Bacteria,2ISRZ@201174|Actinobacteria,4DGA8@85008|Micromonosporales	201174|Actinobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_2303032_0	266117.Rxyl_2946	2.275e-159	530.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158512_k127_2303100_1	42256.RradSPS_0340	2.884e-71	242.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4CPUF@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158512_k127_2303100_0	266117.Rxyl_2946	9.819e-231	739.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158512_k127_2303100_2	266117.Rxyl_2944	1.501e-30	123.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,4CQKV@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158512_k127_2311_5	1121385.AQXW01000004_gene2537	8.448e-31	123.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,1ZVCT@145357|Dermacoccaceae	201174|Actinobacteria	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2158c	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158512_k127_2311_6	266117.Rxyl_2304	2.692e-28	120.0	COG1937@1|root,COG1937@2|Bacteria	2|Bacteria	S	negative regulation of transcription, DNA-templated	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158512_k127_2311_2	266117.Rxyl_2302	1.639e-64	227.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4CPYW@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158512_k127_2311_4	266117.Rxyl_2301	2.601e-36	139.0	COG0776@1|root,COG0776@2|Bacteria,2HN5N@201174|Actinobacteria,4CQJV@84995|Rubrobacteria	84995|Rubrobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158512_k127_2311_0	266117.Rxyl_2300	4.69e-103	343.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CQ00@84995|Rubrobacteria	84995|Rubrobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158512_k127_2311_3	266117.Rxyl_2299	6.48e-56	201.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	MA20_37405	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF836,Redoxin,Thioredoxin
SRR25158512_k127_2311_1	266117.Rxyl_2298	4.035e-100	339.0	COG1686@1|root,COG1686@2|Bacteria,2GJ7C@201174|Actinobacteria,4CP6F@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158512_k127_2312689_7	42256.RradSPS_1211	9.552e-40	162.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4CPJ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
SRR25158512_k127_2312689_9	644283.Micau_1557	3.858e-12	78.0	2E3GE@1|root,32YF6@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2188
SRR25158512_k127_2312689_0	35754.JNYJ01000041_gene1303	1.451e-165	526.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DB1Z@85008|Micromonosporales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_2312689_5	1121346.KB899816_gene3329	2.481e-80	277.0	COG4977@1|root,COG4977@2|Bacteria,1UJ51@1239|Firmicutes,4HV1F@91061|Bacilli,274DZ@186822|Paenibacillaceae	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158512_k127_2312689_2	390989.JOEG01000001_gene5016	4.188e-116	389.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4DMMY@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
SRR25158512_k127_2312689_3	1284679.HMPREF1626_07810	1.656e-108	362.0	COG1175@1|root,COG1175@2|Bacteria,2GJZD@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter (Permease)	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158512_k127_2312689_4	1284679.HMPREF1626_07805	5.848e-98	329.0	COG0395@1|root,COG0395@2|Bacteria,2IGVD@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158512_k127_2312689_6	290340.AAur_1890	3.345e-74	259.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158512_k127_2312689_1	1295642.H839_06074	2.313e-130	425.0	COG1063@1|root,COG1063@2|Bacteria,1TQKZ@1239|Firmicutes,4HEUN@91061|Bacilli	91061|Bacilli	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158512_k127_2319572_2	926560.KE387027_gene952	9.4e-10	62.0	28IZQ@1|root,2Z8X1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158512_k127_2319572_0	266117.Rxyl_3076	0.0	1320.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SRR25158512_k127_2319572_1	266117.Rxyl_3073	1.447e-64	228.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4CQHI@84995|Rubrobacteria	84995|Rubrobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158512_k127_2324422_1	266117.Rxyl_1975	3.509e-223	697.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CPG9@84995|Rubrobacteria	84995|Rubrobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158512_k127_2324422_5	56110.Oscil6304_0245	2.099e-17	81.0	COG0113@1|root,COG0113@2|Bacteria,1G0YH@1117|Cyanobacteria,1H7CK@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158512_k127_2324422_3	266117.Rxyl_1976	5.999e-149	474.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4CPCJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158512_k127_2324422_0	266117.Rxyl_1977	8.09e-239	750.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158512_k127_2324422_4	266117.Rxyl_1978	5.281e-119	390.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4CQ8E@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158512_k127_2324422_2	266117.Rxyl_1979	7.892e-153	489.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CPKE@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158512_k127_2325520_3	926550.CLDAP_12780	9.078e-09	57.0	COG0577@1|root,COG0577@2|Bacteria,2G6CK@200795|Chloroflexi	200795|Chloroflexi	V	COGs COG4591 ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158512_k127_2325520_0	266117.Rxyl_2810	8.532e-195	620.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158512_k127_2325520_1	266117.Rxyl_2809	5.434e-118	385.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CRNI@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_2325520_2	266117.Rxyl_0591	1.37e-68	238.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158512_k127_233108_4	700015.Corgl_0067	3.099e-69	246.0	COG1619@1|root,COG1619@2|Bacteria,2HFBV@201174|Actinobacteria,4CYCM@84998|Coriobacteriia	84998|Coriobacteriia	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158512_k127_233108_0	1122609.AUGT01000009_gene3347	3.709e-129	434.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4DPH8@85009|Propionibacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158512_k127_233108_2	1068980.ARVW01000001_gene7386	1.85e-90	320.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,4DZ95@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158512_k127_233108_1	1298863.AUEP01000008_gene1251	2.449e-98	332.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4DPB4@85009|Propionibacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158512_k127_233108_3	1120950.KB892709_gene4169	1.18e-87	301.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4DPJA@85009|Propionibacteriales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158512_k127_2333695_2	1173028.ANKO01000022_gene5432	4.069e-38	154.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158512_k127_2333695_0	266117.Rxyl_2510	1.609e-108	364.0	COG0784@1|root,COG2202@1|root,COG4585@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158512_k127_2333695_1	266117.Rxyl_2511	2.098e-72	251.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CSY6@84995|Rubrobacteria	84995|Rubrobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_2357868_0	42256.RradSPS_0812	7.95e-322	991.0	COG1429@1|root,COG1429@2|Bacteria,2GK0U@201174|Actinobacteria,4CPSC@84995|Rubrobacteria	84995|Rubrobacteria	H	CobN/Magnesium Chelatase	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
SRR25158512_k127_235857_3	266117.Rxyl_0149	2.326e-30	122.0	COG3540@1|root,COG3540@2|Bacteria,2GNZ5@201174|Actinobacteria,4CRFP@84995|Rubrobacteria	84995|Rubrobacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158512_k127_235857_2	42256.RradSPS_2559	1.752e-46	170.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4CQ50@84995|Rubrobacteria	84995|Rubrobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_235857_1	426117.M446_4604	3.81e-54	197.0	COG1514@1|root,COG1514@2|Bacteria,1RIHA@1224|Proteobacteria,2UAUZ@28211|Alphaproteobacteria,1JRQN@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158512_k127_235857_0	42256.RradSPS_2568	2.151e-123	405.0	COG3301@1|root,COG3301@2|Bacteria,2GJ4S@201174|Actinobacteria	201174|Actinobacteria	P	reductase	nrfD	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158512_k127_2367927_4	266117.Rxyl_0548	1.75e-54	193.0	COG1129@1|root,COG1129@2|Bacteria,2IC7X@201174|Actinobacteria,4CPP9@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158512_k127_2367927_3	42256.RradSPS_0039	3.058e-100	340.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CT9W@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158512_k127_2367927_2	525904.Tter_2021	7.011e-101	338.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158512_k127_2367927_1	1121377.KB906400_gene1311	5.155e-107	357.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	ulaG	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158512_k127_2367927_0	797209.ZOD2009_05012	2.68e-117	384.0	COG0604@1|root,arCOG01458@2157|Archaea,2Y39B@28890|Euryarchaeota,23Z1Y@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_2373526_0	42256.RradSPS_0484	1.597e-201	633.0	COG2837@1|root,COG2837@2|Bacteria,2GIUB@201174|Actinobacteria,4CP9V@84995|Rubrobacteria	84995|Rubrobacteria	P	Dyp-type peroxidase family	-	-	-	ko:K16301	-	-	-	-	ko00000,ko01000,ko02000	2.A.108.2.3	-	-	Dyp_perox
SRR25158512_k127_2373526_2	42256.RradSPS_0485	6.192e-129	421.0	COG2822@1|root,COG2822@2|Bacteria,2GJPY@201174|Actinobacteria,4CU3J@84995|Rubrobacteria	84995|Rubrobacteria	P	Imelysin	-	-	-	ko:K07224	-	-	-	-	ko00000,ko02000	2.A.108.2.3	-	-	Cupredoxin_1,Peptidase_M75
SRR25158512_k127_2373526_1	42256.RradSPS_0486	4.734e-134	432.0	COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,4CPU7@84995|Rubrobacteria	84995|Rubrobacteria	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
SRR25158512_k127_2373526_5	485913.Krac_4003	4.56e-20	93.0	2E4G6@1|root,335WF@2|Bacteria,2G9R2@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2373526_3	479434.Sthe_0342	1.003e-109	361.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRR25158512_k127_2373526_4	479434.Sthe_0341	1.15e-108	353.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158512_k127_2388109_1	1227487.C474_02695	2.256e-40	159.0	COG0596@1|root,arCOG01648@2157|Archaea,2XX6N@28890|Euryarchaeota,23VPX@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158512_k127_2388109_0	234267.Acid_3617	3.169e-52	193.0	COG4758@1|root,COG4758@2|Bacteria,3Y7Z2@57723|Acidobacteria	57723|Acidobacteria	S	N-terminal domain of toast_rack, DUF2154	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
SRR25158512_k127_2390138_1	1306174.JODP01000012_gene6090	6.088e-171	544.0	COG2271@1|root,COG2271@2|Bacteria,2GK3N@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
SRR25158512_k127_2390138_2	42256.RradSPS_2580	1.623e-63	222.0	COG3383@1|root,COG3383@2|Bacteria,2GWFF@201174|Actinobacteria	201174|Actinobacteria	C	Molybdopterin oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin
SRR25158512_k127_2390138_0	42256.RradSPS_2581	1.984e-207	653.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	fdhF	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704	1.17.1.10,1.17.1.9,1.17.99.7	ko:K00123,ko:K05299,ko:K22015	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	iECBD_1354.ECBD_3953,iHN637.CLJU_RS04405,iHN637.CLJU_c06990	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158512_k127_239182_2	317936.Nos7107_4306	8.715e-89	296.0	COG2267@1|root,COG2267@2|Bacteria,1G000@1117|Cyanobacteria,1HQSB@1161|Nostocales	1117|Cyanobacteria	I	Prolyl oligopeptidase family	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158512_k127_239182_1	1380390.JIAT01000013_gene206	2.514e-91	309.0	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria,4CSC7@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_239182_3	1114959.SZMC14600_20679	1.033e-84	291.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria,4E6AG@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158512_k127_239182_7	42256.RradSPS_2313	2.257e-07	62.0	COG3791@1|root,COG3791@2|Bacteria	2|Bacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158512_k127_239182_0	266117.Rxyl_1912	7.841e-147	471.0	COG1525@1|root,COG1988@1|root,COG1525@2|Bacteria,COG1988@2|Bacteria,2GRK1@201174|Actinobacteria,4CQVE@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174,ko:K07038	-	-	-	-	ko00000,ko01000	-	-	-	SNase,YdjM
SRR25158512_k127_239182_4	42256.RradSPS_2256	3.357e-83	286.0	COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_239182_6	42256.RradSPS_2255	3.166e-09	59.0	COG1725@1|root,COG1725@2|Bacteria,2GVVP@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
SRR25158512_k127_2393051_2	1192034.CAP_8821	8.419e-121	398.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_2393051_1	37919.EP51_12385	4.609e-136	445.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria,4FVXT@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158512_k127_2393051_7	266117.Rxyl_2706	2.94e-64	224.0	COG4319@1|root,COG4319@2|Bacteria,2HRVA@201174|Actinobacteria,4CTYP@84995|Rubrobacteria	84995|Rubrobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158512_k127_2393051_5	42256.RradSPS_2879	1.429e-87	293.0	COG1695@1|root,COG1695@2|Bacteria,2IG8U@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_2393051_3	266117.Rxyl_0343	8.41e-106	355.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.301	ko:K21459	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
SRR25158512_k127_2393051_9	67275.JOAP01000001_gene2678	2.514e-20	99.0	COG0346@1|root,COG0346@2|Bacteria,2II17@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_2393051_4	42256.RradSPS_0123	2.393e-95	314.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CQJT@84995|Rubrobacteria	84995|Rubrobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158512_k127_2393051_0	266117.Rxyl_0345	1.047e-153	491.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158512_k127_2393051_6	118161.KB235922_gene1131	1.611e-64	226.0	COG3837@1|root,COG3837@2|Bacteria,1G4Z5@1117|Cyanobacteria	1117|Cyanobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_2393051_8	1144275.COCOR_01842	1.018e-59	209.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_06780	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_2397239_2	266117.Rxyl_0249	1.238e-95	320.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158512_k127_2397239_4	266117.Rxyl_0250	1.09e-72	249.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158512_k127_2397239_7	483219.LILAB_09490	3.666e-27	114.0	COG3631@1|root,COG3631@2|Bacteria,1NNCV@1224|Proteobacteria,43512@68525|delta/epsilon subdivisions,2WZC0@28221|Deltaproteobacteria,2YZZX@29|Myxococcales	28221|Deltaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_2397239_3	1128421.JAGA01000002_gene981	3.896e-83	279.0	COG0652@1|root,COG0652@2|Bacteria,2NPSW@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158512_k127_2397239_5	1336243.JAEA01000011_gene3180	4.126e-38	156.0	COG1309@1|root,COG1309@2|Bacteria,1RKMF@1224|Proteobacteria,2UAP3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WHG
SRR25158512_k127_2397239_6	649638.Trad_0278	6.047e-38	146.0	2CWCM@1|root,32SZF@2|Bacteria,1WN77@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4260)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4260
SRR25158512_k127_2397239_0	512565.AMIS_51330	2.699e-185	601.0	2EZGX@1|root,2ZBAK@2|Bacteria,2IEK8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2397239_1	266117.Rxyl_0252	4.872e-160	511.0	COG1363@1|root,COG1363@2|Bacteria,2ID5X@201174|Actinobacteria,4CP5U@84995|Rubrobacteria	84995|Rubrobacteria	G	peptidase M42	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
SRR25158512_k127_2413359_5	266117.Rxyl_1585	1.856e-106	349.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4CRCX@84995|Rubrobacteria	84995|Rubrobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158512_k127_2413359_3	266117.Rxyl_0464	3.396e-124	412.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	proP	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158512_k127_2413359_6	1245471.PCA10_38700	1.253e-105	351.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,1RR3X@1236|Gammaproteobacteria,1YCT9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_2413359_0	266117.Rxyl_1589	3.181e-162	516.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4CTBJ@84995|Rubrobacteria	84995|Rubrobacteria	C	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_2413359_1	266117.Rxyl_1584	3.441e-152	484.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4CPUV@84995|Rubrobacteria	84995|Rubrobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158512_k127_2413359_2	42256.RradSPS_1068	2.139e-124	417.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4CPVM@84995|Rubrobacteria	84995|Rubrobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158512_k127_2413359_4	266117.Rxyl_1582	8.074e-118	381.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPIQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158512_k127_2413652_4	485913.Krac_10552	5.501e-71	256.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_2413652_3	485913.Krac_6992	1.921e-78	280.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_2413652_5	1380393.JHVP01000003_gene967	2.384e-19	93.0	COG0789@1|root,COG0789@2|Bacteria,2IQGQ@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158512_k127_2413652_0	390989.JOEG01000012_gene3240	1.874e-163	523.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,4DEF2@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08221	-	-	-	-	ko00000,ko02000	2.A.1.32	-	-	MFS_1,Usp
SRR25158512_k127_2413652_1	266117.Rxyl_2909	1.565e-125	407.0	COG0789@1|root,COG1396@1|root,COG1917@1|root,COG0789@2|Bacteria,COG1396@2|Bacteria,COG1917@2|Bacteria,2GNKQ@201174|Actinobacteria,4CTMB@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,MerR_1
SRR25158512_k127_2413652_2	266117.Rxyl_2910	6.943e-92	308.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
SRR25158512_k127_2418965_3	266117.Rxyl_2428	1.257e-59	211.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158512_k127_2418965_0	42256.RradSPS_0540	1.744e-133	430.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CPMX@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158512_k127_2418965_1	266117.Rxyl_2434	1.424e-116	382.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	supH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158512_k127_2418965_2	1382304.JNIL01000001_gene1670	1.889e-64	236.0	COG3180@1|root,COG3180@2|Bacteria,1UVXN@1239|Firmicutes,4HDRW@91061|Bacilli,27ABC@186823|Alicyclobacillaceae	91061|Bacilli	S	Pfam:AmoA	yhjN	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
SRR25158512_k127_2418965_7	565045.NOR51B_899	8.603e-13	70.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,1S08S@1236|Gammaproteobacteria,1J842@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158512_k127_2419702_0	266117.Rxyl_0275	4.406e-169	535.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CPN5@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158512_k127_2419702_1	266117.Rxyl_0682	8.619e-100	330.0	COG3540@1|root,COG3540@2|Bacteria,2GNZ5@201174|Actinobacteria,4CRFP@84995|Rubrobacteria	84995|Rubrobacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158512_k127_2422813_0	42256.RradSPS_2413	3.611e-226	713.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CRBA@84995|Rubrobacteria	84995|Rubrobacteria	V	COG COG1132 ABC-type multidrug transport system ATPase and permease components Defense mechanisms	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158512_k127_2422813_1	42256.RradSPS_2414	2.082e-42	159.0	29ITM@1|root,305QZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2422813_2	42256.RradSPS_2415	1.185e-06	54.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,4CTWQ@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158512_k127_2433664_2	42256.RradSPS_1468	2.472e-114	373.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CPJG@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158512_k127_2433664_8	266117.Rxyl_1460	1.642e-45	169.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SRR25158512_k127_2433664_1	266117.Rxyl_1459	6.161e-127	419.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4CPMA@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158512_k127_2433664_7	42256.RradSPS_1465	1.184e-50	183.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CQJK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158512_k127_2433664_3	525904.Tter_2050	2.404e-89	304.0	COG2390@1|root,COG2390@2|Bacteria,2NQXC@2323|unclassified Bacteria	2|Bacteria	K	Putative sugar-binding domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_28,Sigma70_r4,Sugar-bind
SRR25158512_k127_2433664_0	526227.Mesil_0158	1.907e-143	469.0	COG1653@1|root,COG1653@2|Bacteria,1WJE6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10227	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	SBP_bac_1
SRR25158512_k127_2433664_4	1380763.BG53_08580	2.622e-80	278.0	COG1175@1|root,COG1175@2|Bacteria,1VUDJ@1239|Firmicutes,4I6RZ@91061|Bacilli,26UKB@186822|Paenibacillaceae	91061|Bacilli	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158512_k127_2433664_6	1121382.JQKG01000004_gene4081	2.047e-75	262.0	COG0395@1|root,COG0395@2|Bacteria,1WJEN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10229	ko02010,map02010	M00200	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.5	-	-	BPD_transp_1
SRR25158512_k127_2433664_5	42256.RradSPS_3033	2.231e-79	269.0	COG0240@1|root,COG0240@2|Bacteria,2HYHZ@201174|Actinobacteria,4CQSG@84995|Rubrobacteria	84995|Rubrobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158512_k127_2440850_1	266117.Rxyl_1034	1.913e-80	280.0	COG4689@1|root,COG4689@2|Bacteria,2I55Y@201174|Actinobacteria,4CRVH@84995|Rubrobacteria	84995|Rubrobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
SRR25158512_k127_2440850_0	266117.Rxyl_1033	1.173e-172	548.0	COG2514@1|root,COG2514@2|Bacteria,2I5Q1@201174|Actinobacteria,4CQIX@84995|Rubrobacteria	84995|Rubrobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_2440850_2	1283299.AUKG01000006_gene841	2.786e-61	213.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4CRV0@84995|Rubrobacteria	84995|Rubrobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158512_k127_2449726_2	1123023.JIAI01000001_gene6297	4.242e-67	236.0	COG1172@1|root,COG1172@2|Bacteria,2HB45@201174|Actinobacteria,4E0PI@85010|Pseudonocardiales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158512_k127_2449726_0	862751.SACTE_0376	1.133e-208	663.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158512_k127_2449726_1	287986.DV20_35400	1.798e-73	252.0	COG1879@1|root,COG1879@2|Bacteria,2GJ0Z@201174|Actinobacteria,4E23N@85010|Pseudonocardiales	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158512_k127_2463884_0	1298860.AUEM01000001_gene1693	1.588e-162	522.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FRI2@85023|Microbacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.21,1.2.1.22	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	-	R00203,R01333,R01446	RC00080,RC00104,RC00242	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158512_k127_2463884_1	290399.Arth_1858	3.313e-84	289.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3,NAD_binding_8
SRR25158512_k127_2465728_3	266117.Rxyl_2991	2.312e-48	177.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4CTXT@84995|Rubrobacteria	84995|Rubrobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158512_k127_2465728_0	479431.Namu_0278	5.89e-128	422.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4EU45@85013|Frankiales	201174|Actinobacteria	M	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158512_k127_2465728_2	1173024.KI912153_gene37	2.488e-50	191.0	COG4977@1|root,COG4977@2|Bacteria,1G1HG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158512_k127_2465728_1	42256.RradSPS_0172	5.456e-66	233.0	COG1216@1|root,COG1216@2|Bacteria,2IIII@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2465728_4	383372.Rcas_0599	3.215e-23	100.0	COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,376JH@32061|Chloroflexia	32061|Chloroflexia	S	HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like)	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158512_k127_2472507_4	42256.RradSPS_2477	3.554e-55	196.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158512_k127_2472507_2	42256.RradSPS_3027	2.219e-131	428.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4CR4J@84995|Rubrobacteria	84995|Rubrobacteria	E	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism General function prediction only	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_2472507_1	42256.RradSPS_2474	6.496e-161	518.0	COG4091@1|root,COG4091@2|Bacteria,2I8GM@201174|Actinobacteria	201174|Actinobacteria	-	-	strU	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,NAD_binding_3,SAF
SRR25158512_k127_2472507_7	1158607.UAU_01265	3.201e-14	76.0	COG3571@1|root,COG3571@2|Bacteria,1UIJS@1239|Firmicutes,4ISKJ@91061|Bacilli	91061|Bacilli	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
SRR25158512_k127_2472507_5	1397696.KK211189_gene229	4.851e-23	108.0	COG2267@1|root,COG2267@2|Bacteria,1V3S1@1239|Firmicutes,4HHI0@91061|Bacilli,3WFPN@539002|Bacillales incertae sedis	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
SRR25158512_k127_2472507_3	42256.RradSPS_0765	2.163e-96	322.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	M1-693	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
SRR25158512_k127_2472507_0	525904.Tter_2280	8.397e-183	589.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158512_k127_2538525_3	266117.Rxyl_2373	2.338e-35	137.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4CR8Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
SRR25158512_k127_2538525_1	266117.Rxyl_2374	1.143e-55	197.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4CQQ5@84995|Rubrobacteria	84995|Rubrobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158512_k127_2538525_0	266117.Rxyl_2586	4.58e-287	901.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4CT44@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_31
SRR25158512_k127_2538525_4	1122138.AQUZ01000002_gene1963	5.522e-07	59.0	COG5662@1|root,COG5662@2|Bacteria,2INVC@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158512_k127_2538525_2	266117.Rxyl_0940	8.905e-50	184.0	COG1595@1|root,COG1595@2|Bacteria,2HG2Y@201174|Actinobacteria,4CTJS@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRR25158512_k127_2567032_0	266117.Rxyl_2535	8.317e-137	440.0	COG0567@1|root,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CPG1@84995|Rubrobacteria	84995|Rubrobacteria	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,Biotin_lipoyl,E1_dh,E3_binding,OxoGdeHyase_C,Transket_pyr
SRR25158512_k127_2567032_3	42256.RradSPS_0416	4.53e-29	124.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158512_k127_2567032_2	485913.Krac_6021	3.135e-46	182.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_2567032_1	266117.Rxyl_2537	1.618e-49	180.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CPHX@84995|Rubrobacteria	84995|Rubrobacteria	E	Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158512_k127_2569169_1	266117.Rxyl_3057	2.204e-117	383.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CQ16@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158512_k127_2569169_0	266117.Rxyl_3058	1.264e-132	428.0	COG0331@1|root,COG0331@2|Bacteria	2|Bacteria	I	[acyl-carrier-protein] S-malonyltransferase activity	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645,ko:K13935,ko:K15327,ko:K15329,ko:K15355,ko:K15469	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
SRR25158512_k127_2569169_2	266117.Rxyl_2934	1.749e-59	212.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158512_k127_2570318_1	1336243.JAEA01000003_gene2292	1.643e-18	85.0	COG1670@1|root,COG1670@2|Bacteria,1RH19@1224|Proteobacteria,2U93R@28211|Alphaproteobacteria,1JZ5W@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158512_k127_2570318_0	42256.RradSPS_2574	8.316e-156	505.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4CPX2@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_2570318_2	33876.JNXY01000035_gene742	3.496e-05	56.0	COG5001@1|root,COG5001@2|Bacteria,2H24S@201174|Actinobacteria,4DGSV@85008|Micromonosporales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158512_k127_2594896_1	42256.RradSPS_2531	4.221e-65	227.0	COG0841@1|root,COG0841@2|Bacteria,2GMQX@201174|Actinobacteria	201174|Actinobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158512_k127_2594896_2	42256.RradSPS_2532	4.486e-35	139.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03712	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
SRR25158512_k127_2594896_0	266117.Rxyl_0495	7.237e-118	387.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158512_k127_259647_3	1463885.KL578354_gene8827	1.748e-15	81.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	AIDA,Calx-beta,DUF4347,HemolysinCabind,VCBS
SRR25158512_k127_259647_2	869210.Marky_1956	1.747e-76	265.0	COG1073@1|root,COG1073@2|Bacteria,1WKS0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
SRR25158512_k127_259647_0	1283300.ATXB01000001_gene1721	0.0	1135.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,1RMJ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 31 family	yicI	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SRR25158512_k127_259647_1	266117.Rxyl_2098	5.105e-103	343.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4CQ65@84995|Rubrobacteria	84995|Rubrobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_26228_1	42256.RradSPS_0963	1.917e-135	437.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158512_k127_26228_3	42256.RradSPS_2072	1.317e-81	281.0	COG0388@1|root,COG0388@2|Bacteria,2GM49@201174|Actinobacteria,4CSUE@84995|Rubrobacteria	84995|Rubrobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158512_k127_26228_0	42256.RradSPS_2071	1.374e-235	737.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4CQ78@84995|Rubrobacteria	84995|Rubrobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158512_k127_26228_5	1183438.GKIL_3111	4.834e-22	105.0	COG4291@1|root,COG4291@2|Bacteria,1G4ZQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SRR25158512_k127_26228_4	266117.Rxyl_2895	1.158e-63	225.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria,4CTPZ@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158512_k127_26228_2	1380390.JIAT01000010_gene3361	1.153e-121	400.0	COG3246@1|root,COG3246@2|Bacteria,2I9EQ@201174|Actinobacteria,4CT4T@84995|Rubrobacteria	84995|Rubrobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
SRR25158512_k127_2623854_0	266117.Rxyl_1523	1.27e-198	627.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CPMW@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158512_k127_2623854_9	42256.RradSPS_1531	5.806e-41	152.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CQPP@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158512_k127_2623854_10	266117.Rxyl_1525	8.188e-35	135.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4CQJ4@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158512_k127_2623854_2	266117.Rxyl_1526	5.566e-123	407.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4CPV0@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158512_k127_2623854_3	266117.Rxyl_1528	2.006e-120	395.0	COG1792@1|root,COG1792@2|Bacteria	2|Bacteria	M	regulation of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158512_k127_2623854_1	266117.Rxyl_1529	1.207e-193	606.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CP7J@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158512_k127_2623854_4	266117.Rxyl_1530	5.712e-106	347.0	COG2003@1|root,COG2003@2|Bacteria,2IJG2@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158512_k127_2623854_7	266117.Rxyl_1531	1.681e-62	220.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria,4CQME@84995|Rubrobacteria	84995|Rubrobacteria	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SRR25158512_k127_2623854_6	266117.Rxyl_1532	1.32e-62	217.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4CQFJ@84995|Rubrobacteria	84995|Rubrobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158512_k127_2623854_5	42256.RradSPS_1542	7.899e-74	251.0	COG1933@1|root,COG1933@2|Bacteria,2GU4W@201174|Actinobacteria,4CQ2Q@84995|Rubrobacteria	84995|Rubrobacteria	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
SRR25158512_k127_262903_2	903814.ELI_1846	6.677e-12	70.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes	1239|Firmicutes	C	3-dehydroquinate synthase	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
SRR25158512_k127_262903_0	266117.Rxyl_0833	1.974e-215	679.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4CS1W@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_262903_1	42256.RradSPS_2470	4.959e-176	554.0	COG0596@1|root,COG0596@2|Bacteria,2HBHC@201174|Actinobacteria,4CQDT@84995|Rubrobacteria	84995|Rubrobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_26429_1	675635.Psed_6626	3.236e-07	58.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria,4DZUX@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158512_k127_26429_0	266117.Rxyl_2580	4.401e-84	290.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158512_k127_2643442_0	266117.Rxyl_0011	2.028e-246	766.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CP7M@84995|Rubrobacteria	84995|Rubrobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158512_k127_2643442_1	42256.RradSPS_0012	2.566e-97	320.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2644002_5	266117.Rxyl_1346	1.405e-118	387.0	COG1960@1|root,COG1960@2|Bacteria,2HQT6@201174|Actinobacteria,4CSI2@84995|Rubrobacteria	84995|Rubrobacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_N
SRR25158512_k127_2644002_9	266117.Rxyl_1345	5.002e-76	268.0	COG0500@1|root,COG0500@2|Bacteria,2I2TM@201174|Actinobacteria,4CTQ4@84995|Rubrobacteria	84995|Rubrobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	NodS
SRR25158512_k127_2644002_4	42256.RradSPS_2062	8.571e-125	413.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
SRR25158512_k127_2644002_8	42256.RradSPS_2061	5.66e-82	281.0	COG1215@1|root,COG1215@2|Bacteria,2IHNF@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158512_k127_2644002_3	351607.Acel_1611	5.739e-126	419.0	COG2017@1|root,COG2017@2|Bacteria,2GME9@201174|Actinobacteria,4ETYE@85013|Frankiales	201174|Actinobacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158512_k127_2644002_6	266117.Rxyl_1717	2.471e-115	377.0	COG3718@1|root,COG3718@2|Bacteria,2GM8S@201174|Actinobacteria,4CPJB@84995|Rubrobacteria	84995|Rubrobacteria	G	KduI/IolB family	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
SRR25158512_k127_2644002_0	266117.Rxyl_1718	2.37e-322	995.0	COG3962@1|root,COG3962@2|Bacteria,2GMCJ@201174|Actinobacteria,4CPQQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158512_k127_2644002_7	266117.Rxyl_1722	7.561e-115	385.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4CPZ1@84995|Rubrobacteria	84995|Rubrobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158512_k127_2644002_2	266117.Rxyl_1723	5.877e-147	478.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4CPNT@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
SRR25158512_k127_2644002_1	266117.Rxyl_1728	5.136e-304	943.0	COG0524@1|root,COG3892@1|root,COG0524@2|Bacteria,COG3892@2|Bacteria,2GM3N@201174|Actinobacteria,4CPNV@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158512_k127_2644002_10	1415779.JOMH01000001_gene2561	1.113e-15	76.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,1S4X5@1236|Gammaproteobacteria,1XBVG@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_2655926_2	1121019.AUMN01000010_gene2061	7.532e-19	89.0	2EK1R@1|root,33DS7@2|Bacteria,2GWKM@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
SRR25158512_k127_2655926_0	42256.RradSPS_1270	1.418e-48	183.0	COG2881@1|root,COG2881@2|Bacteria	2|Bacteria	M	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158512_k127_2655926_1	42256.RradSPS_2500	2.5e-43	161.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1611,DUF1611_N,Peptidase_S8
SRR25158512_k127_2659516_2	398767.Glov_0556	4.724e-46	170.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158512_k127_2659516_0	755178.Cyan10605_2068	4.238e-146	477.0	COG0015@1|root,COG0015@2|Bacteria,1G07M@1117|Cyanobacteria	1117|Cyanobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158512_k127_2659516_1	42256.RradSPS_0907	8.154e-127	407.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CPBJ@84995|Rubrobacteria	84995|Rubrobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158512_k127_2659516_3	42256.RradSPS_0908	5.394e-32	125.0	COG1828@1|root,COG1828@2|Bacteria,2HP8J@201174|Actinobacteria,4CQKK@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158512_k127_2671070_7	266117.Rxyl_0117	1.043e-09	59.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4CQ5H@84995|Rubrobacteria	84995|Rubrobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158512_k127_2671070_4	290315.Clim_1874	5.851e-21	104.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
SRR25158512_k127_2671070_1	1230476.C207_00154	4.988e-68	242.0	COG0500@1|root,COG2226@2|Bacteria,1N4AC@1224|Proteobacteria,2VFE9@28211|Alphaproteobacteria,3JZG2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_2671070_0	101510.RHA1_ro02716	1.763e-140	475.0	COG0515@1|root,COG2197@1|root,COG3903@1|root,COG0515@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12,TPR_7
SRR25158512_k127_2671070_2	266117.Rxyl_0118	1.303e-65	231.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4CQMI@84995|Rubrobacteria	84995|Rubrobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158512_k127_2671070_3	42256.RradSPS_2618	5.089e-56	198.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4CT27@84995|Rubrobacteria	84995|Rubrobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158512_k127_2671070_6	266117.Rxyl_0119	4.199e-10	61.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4CT27@84995|Rubrobacteria	84995|Rubrobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	-	-	-	-	-	-	-	-	-	COXG
SRR25158512_k127_267185_2	42256.RradSPS_1159	7.052e-71	242.0	COG2309@1|root,COG2309@2|Bacteria,2INAN@201174|Actinobacteria,4CPAD@84995|Rubrobacteria	84995|Rubrobacteria	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158512_k127_267185_1	266117.Rxyl_1170	1.851e-84	292.0	COG1011@1|root,COG1011@2|Bacteria,2HPG7@201174|Actinobacteria,4CQUS@84995|Rubrobacteria	84995|Rubrobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158512_k127_267185_0	42256.RradSPS_1162	9.033e-107	351.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria	201174|Actinobacteria	GK	polyphosphate glucokinase	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158512_k127_267185_3	525904.Tter_0451	9.908e-34	141.0	COG0300@1|root,COG0300@2|Bacteria,2NQSH@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_267185_6	350054.Mflv_5151	1.302e-08	66.0	COG0398@1|root,COG0398@2|Bacteria,2HPG9@201174|Actinobacteria,2333K@1762|Mycobacteriaceae	201174|Actinobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158512_k127_267185_5	795797.C497_06249	1.167e-11	74.0	COG1238@1|root,arCOG03118@2157|Archaea,2XU8S@28890|Euryarchaeota,23TQV@183963|Halobacteria	183963|Halobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158512_k127_2682025_0	266117.Rxyl_3010	1.713e-98	328.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4CSY8@84995|Rubrobacteria	84995|Rubrobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_2682025_1	266117.Rxyl_0047	9.672e-64	229.0	COG0789@1|root,COG0789@2|Bacteria,2GNID@201174|Actinobacteria,4CTUN@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158512_k127_2682025_2	479434.Sthe_1181	1.554e-51	195.0	2CDJQ@1|root,3304W@2|Bacteria,2G933@200795|Chloroflexi,27Z4Q@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2697091_1	266117.Rxyl_1500	1.386e-74	252.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CPWG@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158512_k127_2697091_2	266117.Rxyl_1499	1.13e-18	95.0	COG4839@1|root,COG4839@2|Bacteria	2|Bacteria	D	cell division protein FtsL	ftsL	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158512_k127_2697091_0	266117.Rxyl_1498	1.418e-157	515.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CPGN@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158512_k127_2707220_3	266117.Rxyl_0748	2.015e-119	386.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_2707220_2	266117.Rxyl_0747	1.828e-132	424.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4CQB7@84995|Rubrobacteria	84995|Rubrobacteria	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158512_k127_2707220_1	266117.Rxyl_0746	4.869e-171	540.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CPXX@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158512_k127_2707220_4	266117.Rxyl_0745	1.586e-66	231.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
SRR25158512_k127_2707220_5	42256.RradSPS_2143	2.531e-44	162.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CQC7@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158512_k127_2707220_0	266117.Rxyl_0743	6.82e-183	576.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158512_k127_2734702_4	266117.Rxyl_1407	6.3e-50	185.0	COG5637@1|root,COG5637@2|Bacteria,2GP5P@201174|Actinobacteria	201174|Actinobacteria	S	cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158512_k127_2734702_2	266117.Rxyl_0877	4.025e-159	512.0	COG0793@1|root,COG0793@2|Bacteria,2GKRP@201174|Actinobacteria,4CPMI@84995|Rubrobacteria	84995|Rubrobacteria	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158512_k127_2734702_1	266117.Rxyl_0876	9.67e-171	550.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4CPAQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158512_k127_2734702_0	266117.Rxyl_0875	2.961e-181	571.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CPQJ@84995|Rubrobacteria	84995|Rubrobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158512_k127_2734702_5	1146883.BLASA_0288	1.236e-36	140.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4ESQD@85013|Frankiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158512_k127_2734702_3	1120950.KB892754_gene6026	3.127e-51	183.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4DPIW@85009|Propionibacteriales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158512_k127_2738505_3	278957.ABEA03000157_gene632	4.113e-49	177.0	COG0667@1|root,COG0667@2|Bacteria,46SC2@74201|Verrucomicrobia,3K7X7@414999|Opitutae	414999|Opitutae	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_2738505_2	443906.CMM_2663	1.039e-57	214.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4FN8S@85023|Microbacteriaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_2738505_0	525904.Tter_0155	7.501e-183	578.0	COG1082@1|root,COG1082@2|Bacteria,2NQCG@2323|unclassified Bacteria	2|Bacteria	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158512_k127_2738505_1	266117.Rxyl_1725	2.299e-171	546.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4CPZ5@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_2738505_4	44251.PDUR_08690	8.156e-22	97.0	COG4813@1|root,COG4813@2|Bacteria,1TPZ1@1239|Firmicutes,4HARS@91061|Bacilli,26S59@186822|Paenibacillaceae	91061|Bacilli	G	Trehalose utilization protein	thuA	-	-	-	-	-	-	-	-	-	-	-	ThuA
SRR25158512_k127_2741202_2	649638.Trad_2940	2.79e-62	217.0	COG0656@1|root,COG0656@2|Bacteria,1WMHW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_2741202_1	937777.Deipe_2663	6.58e-131	427.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158512_k127_2741202_0	1444309.JAQG01000012_gene2010	1.279e-160	537.0	COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli,26TUN@186822|Paenibacillaceae	91061|Bacilli	E	Allantoate amidohydrolase	amaB	-	3.5.3.9	ko:K02083	ko00230,ko01120,map00230,map01120	-	R02423	RC00064	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158512_k127_2744671_2	405948.SACE_7046	3.783e-31	131.0	COG3118@1|root,COG3118@2|Bacteria,2I35R@201174|Actinobacteria	201174|Actinobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
SRR25158512_k127_2744671_0	66869.JNXG01000006_gene1625	3.345e-167	542.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4193H@629295|Streptomyces griseus group	201174|Actinobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158512_k127_2744671_1	1210884.HG799471_gene14698	9.135e-69	241.0	COG0500@1|root,COG0500@2|Bacteria,2J54N@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158512_k127_2744671_3	452652.KSE_27740	1.827e-10	63.0	29SM0@1|root,30DSB@2|Bacteria,2GN13@201174|Actinobacteria,2M16J@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158512_k127_2756731_0	266117.Rxyl_1251	9.339e-128	425.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4CTHM@84995|Rubrobacteria	84995|Rubrobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158512_k127_2756731_1	525904.Tter_1611	1.639e-123	405.0	COG2348@1|root,COG2348@2|Bacteria	2|Bacteria	V	transferase activity, transferring amino-acyl groups	murM	-	2.3.2.10,2.3.2.16,2.3.2.17,2.3.2.18	ko:K05363,ko:K11693,ko:K11694,ko:K11695,ko:K12554,ko:K18354	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	R08776,R08777,R08778,R08779,R08780	RC00055,RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	FemAB
SRR25158512_k127_2756731_2	479434.Sthe_2542	1.641e-26	109.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi,27XZ6@189775|Thermomicrobia	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158512_k127_2760094_1	479434.Sthe_0485	3.019e-69	244.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi,27ZD0@189775|Thermomicrobia	200795|Chloroflexi	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_12
SRR25158512_k127_2760094_3	570268.ANBB01000047_gene3998	1.663e-53	196.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158512_k127_2760094_2	926554.KI912633_gene3971	1.324e-63	224.0	COG1917@1|root,COG1917@2|Bacteria,1WN52@1297|Deinococcus-Thermus	2|Bacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_2760094_4	99598.Cal7507_5639	4.648e-15	83.0	COG0662@1|root,COG0662@2|Bacteria,1G6EN@1117|Cyanobacteria,1HQB6@1161|Nostocales	1117|Cyanobacteria	G	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_2760094_0	266940.Krad_0096	9.72e-84	282.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158512_k127_2763103_1	266117.Rxyl_0311	6.194e-288	896.0	COG3408@1|root,COG3408@2|Bacteria,2ICEJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2763103_0	266117.Rxyl_0312	6.34e-299	925.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4CQV5@84995|Rubrobacteria	84995|Rubrobacteria	EU	Peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158512_k127_2763103_4	266117.Rxyl_0313	4.173e-33	132.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CSFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158512_k127_2763103_3	42256.RradSPS_0189	3.03e-43	164.0	COG1027@1|root,COG1027@2|Bacteria	2|Bacteria	E	Aspartate ammonia-lyase	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158512_k127_2763103_2	42256.RradSPS_0190	7.559e-54	194.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	2.7.11.1	ko:K10914,ko:K12132,ko:K21561	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03000	-	-	-	HTH_Crp_2,Pkinase,cNMP_binding
SRR25158512_k127_2763103_6	42256.RradSPS_0605	1.949e-27	115.0	2EM4J@1|root,33ETZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2773608_2	266117.Rxyl_2162	5.187e-77	259.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CPMH@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158512_k127_2773608_4	266117.Rxyl_2163	2.632e-49	178.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4CQ9X@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158512_k127_2773608_3	42256.RradSPS_1952	2.693e-75	258.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CQ0J@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158512_k127_2773608_0	266117.Rxyl_2165	9.796e-118	382.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CPV5@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158512_k127_2773608_1	42256.RradSPS_1954	2.759e-77	260.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4CQ3Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158512_k127_2773925_2	266117.Rxyl_0225	2.537e-32	126.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPZK@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SRR25158512_k127_2773925_1	266117.Rxyl_0223	1.636e-174	554.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4CPAN@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_2773925_0	266117.Rxyl_0222	6.783e-264	819.0	COG1953@1|root,COG1953@2|Bacteria,2GJXN@201174|Actinobacteria	201174|Actinobacteria	FH	permease for cytosine purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR25158512_k127_2774786_0	886293.Sinac_1023	4.34e-109	361.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
SRR25158512_k127_2774786_2	324057.Pjdr2_0990	5.706e-10	65.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,4I26M@91061|Bacilli,2705Y@186822|Paenibacillaceae	91061|Bacilli	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_2774786_1	443218.AS9A_4259	5.25e-12	70.0	2EFXV@1|root,339Q3@2|Bacteria	2|Bacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_2774786_3	631362.Thi970DRAFT_03011	1.109e-05	55.0	2AGKH@1|root,316TP@2|Bacteria,1NIDF@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Nitrile hydratase, alpha chain	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_2778188_0	43354.JOIJ01000011_gene2664	1.935e-180	582.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4DYJ7@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Glyco_hydro_16
SRR25158512_k127_2798109_1	266117.Rxyl_0834	3.533e-95	315.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CP9F@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158512_k127_2798109_0	266117.Rxyl_0835	6.182e-103	352.0	COG0129@1|root,COG0129@2|Bacteria	2|Bacteria	EG	dihydroxy-acid dehydratase activity	-	-	4.2.1.25,4.2.1.9	ko:K01687,ko:K13875	ko00053,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00053,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02522,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158512_k127_2798158_1	316274.Haur_3795	1.429e-53	194.0	COG1528@1|root,COG1528@2|Bacteria,2G8JG@200795|Chloroflexi,37728@32061|Chloroflexia	32061|Chloroflexia	C	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
SRR25158512_k127_2798158_2	266117.Rxyl_1184	2.941e-53	190.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158512_k127_2798158_0	266117.Rxyl_1211	6.142e-74	255.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,4CQAZ@84995|Rubrobacteria	84995|Rubrobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158512_k127_2798158_4	211114.JOEF01000009_gene1680	2.553e-09	63.0	2DS6C@1|root,33ERP@2|Bacteria,2GU4V@201174|Actinobacteria,4E6NP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2798158_3	42256.RradSPS_1368	1.184e-50	183.0	COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524
SRR25158512_k127_2805295_11	1210884.HG799467_gene13373	2.446e-39	154.0	COG3590@1|root,COG3590@2|Bacteria,2J4HC@203682|Planctomycetes	203682|Planctomycetes	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2805295_4	1122138.AQUZ01000004_gene897	6.434e-66	244.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4DPWR@85009|Propionibacteriales	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
SRR25158512_k127_2805295_17	266117.Rxyl_2515	1.311e-10	63.0	COG3328@1|root,COG3328@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158512_k127_2805295_16	1158165.KB898871_gene2438	9.891e-13	71.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,1S08N@1236|Gammaproteobacteria,1WZ2T@135613|Chromatiales	135613|Chromatiales	L	Helix-turn-helix domain of resolvase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase,TetR_N
SRR25158512_k127_2805295_8	266117.Rxyl_1209	9.301e-44	167.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
SRR25158512_k127_2805295_3	42256.RradSPS_0576	2.476e-117	385.0	COG2181@1|root,COG2181@2|Bacteria,2GJVI@201174|Actinobacteria,4CT0W@84995|Rubrobacteria	84995|Rubrobacteria	C	nitrate reductase, gamma subunit	-	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
SRR25158512_k127_2805295_5	266117.Rxyl_1207	6.216e-58	209.0	COG2180@1|root,COG2180@2|Bacteria,2IAQV@201174|Actinobacteria,4CTJQ@84995|Rubrobacteria	84995|Rubrobacteria	C	nitrate reductase molybdenum cofactor assembly chaperone	-	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
SRR25158512_k127_2805295_1	42256.RradSPS_0574	2.045e-304	943.0	COG1140@1|root,COG1140@2|Bacteria,2GJ8P@201174|Actinobacteria,4CRN0@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
SRR25158512_k127_2805295_0	42256.RradSPS_0573	0.0	2303.0	COG5013@1|root,COG5013@2|Bacteria,2GKZU@201174|Actinobacteria,4CRPX@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
SRR25158512_k127_2805295_2	42256.RradSPS_0572	1.299e-183	583.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4CQM5@84995|Rubrobacteria	84995|Rubrobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
SRR25158512_k127_2805295_6	42256.RradSPS_0570	4.969e-52	188.0	COG1959@1|root,COG1959@2|Bacteria,2GS0E@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158512_k127_2805295_10	42256.RradSPS_0568	2.274e-41	156.0	COG1917@1|root,COG1917@2|Bacteria,2GWWK@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_2805295_13	42256.RradSPS_0564	3.685e-20	103.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	Cupin_2,UPF0054
SRR25158512_k127_2805295_9	266117.Rxyl_1186	2.173e-41	167.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158512_k127_2805295_14	1120972.AUMH01000011_gene133	4.354e-20	94.0	COG0582@1|root,COG0582@2|Bacteria,1W09X@1239|Firmicutes	1239|Firmicutes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158512_k127_2805295_15	1122221.JHVI01000004_gene161	2.036e-14	74.0	2DCT2@1|root,32U08@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
SRR25158512_k127_2806564_2	266117.Rxyl_1153	1.977e-39	149.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4CQ1B@84995|Rubrobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158512_k127_2806564_1	1385510.N781_09495	3.329e-85	295.0	COG5502@1|root,COG5502@2|Bacteria,1TSZP@1239|Firmicutes,4HCBP@91061|Bacilli,2Y8MY@289201|Pontibacillus	91061|Bacilli	S	conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2806564_0	42256.RradSPS_0399	0.0	1350.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CU4U@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM UvrB UvrC protein AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158512_k127_2806564_3	1380390.JIAT01000016_gene5488	1.1e-33	138.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CT9W@84995|Rubrobacteria	84995|Rubrobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158512_k127_2807678_4	436229.JOEH01000021_gene7641	2.46e-07	59.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,2NIPJ@228398|Streptacidiphilus	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_2807678_1	485913.Krac_9544	4.044e-79	270.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158512_k127_2807678_3	1157638.KB892164_gene3496	1.604e-19	92.0	COG1359@1|root,COG1359@2|Bacteria,2IRF2@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158512_k127_2807678_0	469383.Cwoe_0514	5.531e-89	299.0	28SI0@1|root,2ZEUB@2|Bacteria,2GNT0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR25158512_k127_2807678_2	525909.Afer_0695	2.371e-41	155.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4CNCN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_2811717_1	1108045.GORHZ_053_00570	1.81e-56	201.0	COG0300@1|root,COG0300@2|Bacteria,2IIVW@201174|Actinobacteria,4GE8H@85026|Gordoniaceae	201174|Actinobacteria	S	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_2811717_0	1033736.CAHK01000029_gene1370	1.014e-97	324.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4F8DH@85019|Brevibacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_2811717_3	1185876.BN8_03931	2.117e-43	166.0	COG1917@1|root,COG1917@2|Bacteria,4NUTA@976|Bacteroidetes,47RVA@768503|Cytophagia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_2811717_5	1306990.BARG01000033_gene3884	2.749e-20	96.0	COG0748@1|root,COG0748@2|Bacteria,2IBET@201174|Actinobacteria	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_2811717_4	479431.Namu_0784	8.126e-39	151.0	COG0748@1|root,COG0748@2|Bacteria,2IBET@201174|Actinobacteria	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_2811717_2	570268.ANBB01000047_gene3998	7.147e-52	190.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158512_k127_2820636_0	266117.Rxyl_0843	3.483e-153	496.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2IB2S@201174|Actinobacteria,4CU33@84995|Rubrobacteria	84995|Rubrobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
SRR25158512_k127_2820636_2	66874.JOFS01000055_gene1724	7.803e-63	228.0	COG0500@1|root,COG0500@2|Bacteria,2I3FS@201174|Actinobacteria	201174|Actinobacteria	Q	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158512_k127_2820636_1	1713.JOFV01000003_gene1640	4.52e-91	308.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4F23K@85016|Cellulomonadaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158512_k127_2838095_1	266117.Rxyl_0490	6.635e-88	295.0	COG2313@1|root,COG2313@2|Bacteria,2GK19@201174|Actinobacteria,4CPET@84995|Rubrobacteria	84995|Rubrobacteria	Q	Indigoidine synthase A like protein	-	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158512_k127_2838095_0	266117.Rxyl_0491	1.782e-106	352.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4CQ1P@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158512_k127_2838095_4	479432.Sros_4201	1.473e-28	123.0	COG4319@1|root,COG4319@2|Bacteria,2IRHC@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_2838095_3	1380391.JIAS01000014_gene2301	1.285e-29	122.0	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,2UAPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158512_k127_2838095_2	42256.RradSPS_2537	2.126e-66	234.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158512_k127_2841686_2	42256.RradSPS_1751	6.185e-104	342.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158512_k127_2841686_1	42256.RradSPS_1750	2.495e-133	433.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CQGP@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
SRR25158512_k127_2841686_0	266117.Rxyl_1971	5.844e-182	581.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria	201174|Actinobacteria	F	Pfam Amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158512_k127_284216_0	266117.Rxyl_1604	7.454e-222	694.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4CPE0@84995|Rubrobacteria	84995|Rubrobacteria	K	RNB	-	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
SRR25158512_k127_284216_2	42256.RradSPS_1555	9.433e-71	243.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CQII@84995|Rubrobacteria	84995|Rubrobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158512_k127_284216_1	266117.Rxyl_2686	1.954e-76	265.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158512_k127_2842981_5	42256.RradSPS_2911	1.729e-11	66.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ydgJ	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
SRR25158512_k127_2842981_6	1048339.KB913029_gene3669	7.463e-05	45.0	COG0607@1|root,COG0607@2|Bacteria,2IN5N@201174|Actinobacteria,4EW3U@85013|Frankiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158512_k127_2842981_4	42256.RradSPS_2110	3.099e-16	80.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF4344,Rhodanese
SRR25158512_k127_2842981_3	1078020.KEK_14373	2.015e-32	132.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,239MD@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	ddn	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158512_k127_2842981_1	42256.RradSPS_2112	9.037e-97	324.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158512_k127_2842981_2	42256.RradSPS_2113	3.458e-91	310.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158512_k127_2842981_0	42256.RradSPS_2114	3.133e-97	321.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158512_k127_284599_0	1382306.JNIM01000001_gene1355	1.763e-48	185.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08224	-	-	-	-	ko00000,ko02000	2.A.1.36	-	-	MFS_1,Sugar_tr
SRR25158512_k127_284599_1	1122603.ATVI01000005_gene3515	5.715e-21	105.0	COG2911@1|root,COG2911@2|Bacteria,1MZD7@1224|Proteobacteria,1T439@1236|Gammaproteobacteria,1X8XQ@135614|Xanthomonadales	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2856348_1	266117.Rxyl_3157	6.233e-60	211.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	dpnA	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158512_k127_2856348_0	1068980.ARVW01000001_gene4474	1.649e-94	322.0	COG2267@1|root,COG2267@2|Bacteria,2I5HD@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158512_k127_2856348_3	420324.KI912020_gene7593	1.546e-17	84.0	COG3554@1|root,COG3554@2|Bacteria,1MZEY@1224|Proteobacteria,2VGHP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158512_k127_2856348_2	62928.azo1319	9.594e-23	99.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria,2KUB0@206389|Rhodocyclales	206389|Rhodocyclales	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158512_k127_2857353_0	525904.Tter_2254	1.48e-200	636.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2NQGA@2323|unclassified Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	rhaD	-	1.1.1.1,4.1.2.19	ko:K00001,ko:K01629	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R01785,R02124,R02263,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00438,RC00599,RC00603,RC00604,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,adh_short_C2
SRR25158512_k127_2857353_1	1122132.AQYH01000006_gene3654	2.478e-40	153.0	COG3254@1|root,COG3254@2|Bacteria	2|Bacteria	S	rhamnose metabolic process	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
SRR25158512_k127_2857353_4	1150469.RSPPHO_02148	0.0001609	47.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TQWG@28211|Alphaproteobacteria,2JPYF@204441|Rhodospirillales	204441|Rhodospirillales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158512_k127_2857353_2	266117.Rxyl_2614	1.275e-26	113.0	2DNMG@1|root,32Y46@2|Bacteria,2HN7D@201174|Actinobacteria,4CQM1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2857353_3	450851.PHZ_p0296	7.691e-12	73.0	COG0491@1|root,COG0491@2|Bacteria,1RJMQ@1224|Proteobacteria,2UII5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158512_k127_2870388_1	266117.Rxyl_1800	6.391e-176	562.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4CPXB@84995|Rubrobacteria	84995|Rubrobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
SRR25158512_k127_2870388_3	266117.Rxyl_1799	1.446e-42	160.0	COG1006@1|root,COG1006@2|Bacteria,2ISBC@201174|Actinobacteria,4CQW3@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM NADH-ubiquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
SRR25158512_k127_2870388_0	266117.Rxyl_1798	4.937e-209	668.0	COG0651@1|root,COG0651@2|Bacteria,2HAC7@201174|Actinobacteria,4CQ74@84995|Rubrobacteria	84995|Rubrobacteria	CP	NADH ubiquinone plastoquinone	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SRR25158512_k127_2870388_2	266117.Rxyl_1797	1.474e-66	237.0	COG1863@1|root,COG1863@2|Bacteria,2IT9T@201174|Actinobacteria,4CTPK@84995|Rubrobacteria	84995|Rubrobacteria	P	Cation antiporter	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
SRR25158512_k127_2873206_1	266117.Rxyl_2735	2.611e-105	344.0	COG1960@1|root,COG1960@2|Bacteria,2GNFB@201174|Actinobacteria,4CPM4@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_2873206_0	42256.RradSPS_1692	8.852e-164	526.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CPIW@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158512_k127_2873206_2	196162.Noca_2658	3.696e-87	295.0	COG2072@1|root,COG2072@2|Bacteria,2GJWE@201174|Actinobacteria,4DRR6@85009|Propionibacteriales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	K_oxygenase,Pyr_redox_2,Pyr_redox_3
SRR25158512_k127_2882744_6	266117.Rxyl_0697	5.156e-91	304.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,4CTN9@84995|Rubrobacteria	84995|Rubrobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158512_k127_2882744_10	266117.Rxyl_0696	3.034e-33	143.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158512_k127_2882744_3	266117.Rxyl_1716	9.054e-266	824.0	COG1012@1|root,COG1012@2|Bacteria,2HEP1@201174|Actinobacteria,4CPS4@84995|Rubrobacteria	84995|Rubrobacteria	C	COG COG1012 NAD-dependent aldehyde dehydrogenases Energy production and conversion	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158512_k127_2882744_13	525904.Tter_1970	2.142e-12	68.0	COG1063@1|root,COG1063@2|Bacteria,2NP68@2323|unclassified Bacteria	2|Bacteria	E	Zinc-binding dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_2882744_14	438753.AZC_3271	5.053e-09	57.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,2TSUK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_2882744_8	42256.RradSPS_0690	1.047e-64	225.0	2FC0J@1|root,3444Q@2|Bacteria,2H606@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2882744_4	42256.RradSPS_2184	1.295e-135	436.0	COG3546@1|root,COG3546@2|Bacteria,2GKIM@201174|Actinobacteria,4CPK5@84995|Rubrobacteria	84995|Rubrobacteria	P	Manganese containing catalase	-	-	-	-	-	-	-	-	-	-	-	-	Mn_catalase
SRR25158512_k127_2882744_1	266117.Rxyl_0680	5.689e-283	876.0	COG1866@1|root,COG1866@2|Bacteria,2H3DE@201174|Actinobacteria	201174|Actinobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158512_k127_2882744_0	42256.RradSPS_0058	3.817e-286	895.0	COG0021@1|root,COG0021@2|Bacteria,2I36F@201174|Actinobacteria,4CU3Y@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the transketolase family	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158512_k127_2882744_2	485913.Krac_2635	4.477e-267	852.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
SRR25158512_k127_2882744_12	1306990.BARG01000033_gene3884	1.54e-18	91.0	COG0748@1|root,COG0748@2|Bacteria,2IBET@201174|Actinobacteria	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_2882744_9	318424.EU78_20540	1.514e-38	150.0	COG0748@1|root,COG0748@2|Bacteria,2IBET@201174|Actinobacteria,23914@1762|Mycobacteriaceae	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_2882744_5	82654.Pse7367_0547	1.528e-104	350.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1H7PH@1150|Oscillatoriales	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
SRR25158512_k127_2890104_1	42256.RradSPS_1238	7.35e-91	302.0	COG2220@1|root,COG2220@2|Bacteria,2HP2V@201174|Actinobacteria,4CQDX@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158512_k127_2890104_0	266117.Rxyl_1262	1.16e-117	386.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4CRP2@84995|Rubrobacteria	84995|Rubrobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158512_k127_2913286_0	42256.RradSPS_1093	4.125e-102	334.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CPW7@84995|Rubrobacteria	84995|Rubrobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158512_k127_2913286_1	266117.Rxyl_1104	5.675e-100	329.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CQ9Q@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158512_k127_2913286_3	756499.Desde_2261	5.042e-26	116.0	COG1670@1|root,COG1670@2|Bacteria,1VATK@1239|Firmicutes,24Q0Z@186801|Clostridia,266TX@186807|Peptococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158512_k127_2913286_2	266117.Rxyl_1105	5.786e-96	319.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CPKT@84995|Rubrobacteria	84995|Rubrobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158512_k127_2922680_4	266117.Rxyl_0939	1.92e-32	135.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158512_k127_2922680_1	266117.Rxyl_0940	8.332e-61	219.0	COG1595@1|root,COG1595@2|Bacteria,2HG2Y@201174|Actinobacteria,4CTJS@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRR25158512_k127_2922680_0	42256.RradSPS_2136	3.489e-120	395.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,4CRQX@84995|Rubrobacteria	84995|Rubrobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158512_k127_2922680_3	42256.RradSPS_1337	6.59e-40	161.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158512_k127_2922680_2	266117.Rxyl_0750	1.075e-48	177.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158512_k127_292437_1	1173027.Mic7113_2950	3.721e-154	492.0	COG0435@1|root,COG0435@2|Bacteria,1G0WI@1117|Cyanobacteria,1H7YP@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Glutathione S-transferase, C-terminal domain	-	-	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
SRR25158512_k127_292437_2	266117.Rxyl_2009	1.972e-137	442.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CS0B@84995|Rubrobacteria	84995|Rubrobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158512_k127_292437_0	266117.Rxyl_2010	1.003e-321	992.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CPMP@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SRR25158512_k127_292437_3	756067.MicvaDRAFT_5451	2.668e-35	142.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
SRR25158512_k127_2934468_4	1944.JOAZ01000002_gene5600	0.0002091	52.0	COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria,419VC@629295|Streptomyces griseus group	201174|Actinobacteria	KLT	Protein tyrosine kinase	pkaE	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_19
SRR25158512_k127_2934468_2	110319.CF8_0881	2.207e-13	79.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4DS73@85009|Propionibacteriales	201174|Actinobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_2934468_3	1280952.HJA_02165	3.924e-12	76.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,44032@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_2934468_1	1077972.ARGLB_092_00810	1.032e-28	120.0	2DTAF@1|root,33JFA@2|Bacteria,2I5U4@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_2934468_0	266117.Rxyl_1029	1.597e-122	398.0	COG0179@1|root,COG0179@2|Bacteria,2GN1K@201174|Actinobacteria,4CPUK@84995|Rubrobacteria	84995|Rubrobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158512_k127_2937763_0	266117.Rxyl_2115	7.26e-169	536.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CPNJ@84995|Rubrobacteria	84995|Rubrobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158512_k127_2937763_2	1356854.N007_12800	4.85e-51	188.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,279NY@186823|Alicyclobacillaceae	91061|Bacilli	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
SRR25158512_k127_2937763_1	266117.Rxyl_2117	4.433e-51	183.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CPI7@84995|Rubrobacteria	84995|Rubrobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158512_k127_2946383_2	266117.Rxyl_0425	1.081e-69	247.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4CPYY@84995|Rubrobacteria	84995|Rubrobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158512_k127_2946383_1	266117.Rxyl_0424	8.34e-141	454.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,BTAD
SRR25158512_k127_2946383_0	266117.Rxyl_0422	0.0	1111.0	COG1966@1|root,COG1966@2|Bacteria,2GIYX@201174|Actinobacteria	201174|Actinobacteria	T	Carbon starvation protein	cstA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158512_k127_2955771_7	1380356.JNIK01000014_gene3372	2.295e-32	136.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EUW7@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,Trans_reg_C
SRR25158512_k127_2955771_9	1288298.rosmuc_00250	7.915e-12	72.0	COG2931@1|root,COG2931@2|Bacteria,1N161@1224|Proteobacteria,2U5GB@28211|Alphaproteobacteria,46N9X@74030|Roseovarius	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_2955771_8	266117.Rxyl_3189	7.278e-32	130.0	COG1917@1|root,COG1917@2|Bacteria,2I3J0@201174|Actinobacteria,4CQVJ@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_2955771_1	1380386.JIAW01000005_gene1435	5.596e-146	469.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,237Y2@1762|Mycobacteriaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158512_k127_2955771_6	1121946.AUAX01000010_gene3729	1.103e-41	157.0	COG0748@1|root,COG0748@2|Bacteria,2I2TX@201174|Actinobacteria,4DF7H@85008|Micromonosporales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Hemerythrin
SRR25158512_k127_2955771_2	485913.Krac_4879	1.049e-104	347.0	COG1028@1|root,COG1028@2|Bacteria	485913.Krac_4879|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2955771_4	42256.RradSPS_2313	9.257e-58	204.0	COG3791@1|root,COG3791@2|Bacteria	2|Bacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158512_k127_2955771_0	1040989.AWZU01000125_gene3972	3.83e-252	786.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3JTRW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	pcpB	-	1.14.13.127,1.14.13.50	ko:K03391,ko:K05712	ko00360,ko00361,ko00364,ko01100,ko01120,ko01220,map00360,map00361,map00364,map01100,map01120,map01220	M00545	R03982,R06786,R06787,R07779	RC00236,RC01932	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158512_k127_2955771_3	526227.Mesil_1129	4.779e-89	303.0	COG0697@1|root,COG0697@2|Bacteria,1WKUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2955771_5	350058.Mvan_2288	1.811e-44	170.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,2364E@1762|Mycobacteriaceae	201174|Actinobacteria	K	GntR family	-	-	-	ko:K03489,ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158512_k127_297939_1	649747.HMPREF0083_02048	9.785e-54	196.0	COG0154@1|root,COG0154@2|Bacteria,1TR9X@1239|Firmicutes,4HAYP@91061|Bacilli,26WNA@186822|Paenibacillaceae	91061|Bacilli	J	amidotransferase, A subunit	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158512_k127_297939_0	1218075.BAYA01000040_gene6455	1.991e-189	603.0	COG1457@1|root,COG1457@2|Bacteria,1QYVS@1224|Proteobacteria,2VN4H@28216|Betaproteobacteria,1K1JN@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the purine-cytosine permease (2.A.39) family	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR25158512_k127_297939_2	216594.MMAR_3620	9.006e-19	88.0	COG0589@1|root,COG0589@2|Bacteria,2I8XM@201174|Actinobacteria,2345H@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	uspA4	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_2980535_1	266117.Rxyl_0062	1.403e-72	250.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4CQB2@84995|Rubrobacteria	84995|Rubrobacteria	G	COG COG1653 ABC-type sugar transport system periplasmic component Carbohydrate transport and metabolism	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
SRR25158512_k127_2980535_0	743719.PaelaDRAFT_5004	6.492e-89	304.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC6I@91061|Bacilli,26TJS@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_2980535_2	358681.BBR47_17150	3.459e-67	238.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HBTY@91061|Bacilli,26SY9@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_2980981_0	1229172.JQFA01000004_gene1535	5.802e-62	235.0	COG1305@1|root,COG1305@2|Bacteria,1FZW2@1117|Cyanobacteria,1H7X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
SRR25158512_k127_2980981_3	443218.AS9A_3167	4.905e-37	147.0	2BAPR@1|root,3244M@2|Bacteria,2H8Y8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2980981_2	1120972.AUMH01000007_gene1618	9.684e-47	175.0	COG1695@1|root,COG1695@2|Bacteria,1VBBY@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_2980981_1	219305.MCAG_03369	9.846e-57	205.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria,4DAFJ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2982921_1	266117.Rxyl_0215	1.365e-72	248.0	COG1222@1|root,COG1222@2|Bacteria,2GJNW@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA
SRR25158512_k127_2982921_0	479432.Sros_7119	1.103e-75	260.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4EJDM@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_2982921_2	1283283.ATXA01000031_gene4211	6.033e-54	192.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4ET6N@85013|Frankiales	201174|Actinobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_2985357_2	266117.Rxyl_1273	3.674e-30	121.0	COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria	201174|Actinobacteria	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158512_k127_2985357_0	266117.Rxyl_1272	3.698e-201	634.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4CQH1@84995|Rubrobacteria	84995|Rubrobacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158512_k127_2985357_1	42256.RradSPS_1246	1.603e-104	344.0	COG0010@1|root,COG0010@2|Bacteria,2IJJX@201174|Actinobacteria,4CS3V@84995|Rubrobacteria	84995|Rubrobacteria	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158512_k127_2986070_4	756067.MicvaDRAFT_3142	8.912e-30	139.0	COG0642@1|root,COG2202@1|root,COG3322@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3322@2|Bacteria,1G4DT@1117|Cyanobacteria,1HH4G@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_9
SRR25158512_k127_2986070_0	1123023.JIAI01000002_gene5619	4.575e-107	385.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4DZGK@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PAS_4
SRR25158512_k127_2986070_3	266117.Rxyl_2366	2.794e-38	147.0	2BXAG@1|root,32RI7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2986070_5	1235803.C825_04548	1.254e-12	76.0	2DR81@1|root,33AM9@2|Bacteria,4P4HR@976|Bacteroidetes,2FTPU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2986070_1	1048339.KB913029_gene1773	6.801e-60	213.0	COG3576@1|root,COG3576@2|Bacteria,2GKCF@201174|Actinobacteria,4ESVI@85013|Frankiales	201174|Actinobacteria	S	PFAM Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_2986070_2	1463934.JOCF01000123_gene7312	4.78e-44	166.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_2986109_6	485913.Krac_5377	3.868e-82	278.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi	2|Bacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07693	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158512_k127_2986109_3	358396.C445_09598	4.186e-152	494.0	arCOG02685@1|root,arCOG02685@2157|Archaea,2XV10@28890|Euryarchaeota,23SHT@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158512_k127_2986109_0	266117.Rxyl_2386	2.626e-268	840.0	COG3243@1|root,COG3243@2|Bacteria,2GNYP@201174|Actinobacteria	201174|Actinobacteria	I	Poly-beta-hydroxybutyrate polymerase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
SRR25158512_k127_2986109_2	42256.RradSPS_2089	4.507e-197	621.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CP66@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_2986109_4	485913.Krac_4934	3.386e-118	391.0	COG2041@1|root,COG2041@2|Bacteria,2G6QP@200795|Chloroflexi	2|Bacteria	C	PFAM Mo-co oxidoreductase dimerisation domain	-	-	1.8.3.1	ko:K00387	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00533	RC00168	ko00000,ko00001,ko01000	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158512_k127_2986109_8	42256.RradSPS_0606	4.137e-51	186.0	COG1670@1|root,COG1670@2|Bacteria,2HP6J@201174|Actinobacteria,4CQIP@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158512_k127_2986109_1	266117.Rxyl_2389	4.358e-213	666.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPCN@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158512_k127_2986109_7	266117.Rxyl_2392	3.311e-66	228.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	phaQ	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_2986109_5	266117.Rxyl_2393	9.096e-89	298.0	COG1028@1|root,COG1028@2|Bacteria,2GMWG@201174|Actinobacteria	201174|Actinobacteria	IQ	reductase	fabG	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_2986379_3	765910.MARPU_08395	5.869e-13	78.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RZ20@1236|Gammaproteobacteria,1WY9D@135613|Chromatiales	135613|Chromatiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
SRR25158512_k127_2986379_2	243231.GSU0010	1.051e-38	154.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	fgrL	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158512_k127_2986379_1	383372.Rcas_4227	4.665e-83	282.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_2987837_0	266117.Rxyl_2871	4.355e-116	381.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
SRR25158512_k127_2987837_2	42256.RradSPS_2286	2.3e-76	264.0	COG0457@1|root,COG0457@2|Bacteria	42256.RradSPS_2286|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	-
SRR25158512_k127_2987837_3	42256.RradSPS_2285	5.165e-62	222.0	COG0457@1|root,COG0457@2|Bacteria	42256.RradSPS_2285|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_2987837_4	266117.Rxyl_2867	6.489e-54	191.0	COG4293@1|root,COG4293@2|Bacteria,2IG98@201174|Actinobacteria,4CQEX@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158512_k127_3002468_0	266117.Rxyl_0315	0.0	1296.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2GIV1@201174|Actinobacteria,4CPAY@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR25158512_k127_300711_5	266117.Rxyl_0817	3.835e-75	261.0	COG3568@1|root,COG3568@2|Bacteria,2H3ST@201174|Actinobacteria	201174|Actinobacteria	G	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158512_k127_300711_4	1123024.AUII01000025_gene2112	1.062e-78	268.0	COG1174@1|root,COG1174@2|Bacteria,2GMQT@201174|Actinobacteria,4DXYP@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system, permease component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158512_k127_300711_1	42256.RradSPS_2078	1.308e-175	557.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4CR1Y@84995|Rubrobacteria	84995|Rubrobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158512_k127_300711_3	1123024.AUII01000025_gene2110	6.862e-81	276.0	COG1174@1|root,COG1174@2|Bacteria,2H9I7@201174|Actinobacteria,4EAPC@85010|Pseudonocardiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158512_k127_300711_2	42256.RradSPS_2076	3.172e-112	371.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4CS26@84995|Rubrobacteria	84995|Rubrobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158512_k127_300711_0	266117.Rxyl_2375	0.0	1274.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria,4CU1R@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
SRR25158512_k127_3022032_1	266117.Rxyl_0273	2.752e-68	236.0	COG3044@1|root,COG3044@2|Bacteria,2GN91@201174|Actinobacteria	201174|Actinobacteria	T	ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
SRR25158512_k127_3022032_0	266117.Rxyl_0272	2.138e-107	353.0	COG1183@1|root,COG1183@2|Bacteria,2IC3M@201174|Actinobacteria	201174|Actinobacteria	I	phosphatidylcholine synthase	pcs	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158512_k127_3022032_2	1297742.A176_04256	4.625e-40	153.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158512_k127_3030672_1	285535.JOEY01000018_gene7511	1.875e-78	276.0	COG2986@1|root,COG2986@2|Bacteria,2I9PJ@201174|Actinobacteria	201174|Actinobacteria	E	Aromatic amino acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Lyase_aromatic
SRR25158512_k127_3030672_0	266117.Rxyl_0583	9.693e-315	976.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4CRM0@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158512_k127_3030672_2	266117.Rxyl_0584	3.008e-38	145.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4CPN7@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158512_k127_3056540_0	1382306.JNIM01000001_gene2674	1.158e-107	355.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158512_k127_3056540_1	1122182.KB903813_gene2181	7.778e-50	182.0	COG1765@1|root,COG1765@2|Bacteria,2IMBV@201174|Actinobacteria,4DKMC@85008|Micromonosporales	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158512_k127_3056540_2	298654.FraEuI1c_3352	5.165e-22	98.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158512_k127_3059445_0	42256.RradSPS_1967	0.0	1178.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CPPI@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158512_k127_3059445_1	485913.Krac_4425	5.355e-72	257.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_3059445_3	42256.RradSPS_1985	1.129e-29	122.0	COG3654@1|root,COG3654@2|Bacteria,2IR34@201174|Actinobacteria	201174|Actinobacteria	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158512_k127_3059445_4	1336249.JADW01000023_gene2727	0.0003638	46.0	COG2336@1|root,COG2336@2|Bacteria,1NNYF@1224|Proteobacteria,2UM8P@28211|Alphaproteobacteria,4BGYE@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158512_k127_3059445_2	266117.Rxyl_2178	1.299e-51	186.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CP8Q@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
SRR25158512_k127_3062448_7	266117.Rxyl_1509	1.596e-18	89.0	COG0319@1|root,COG0319@2|Bacteria,2HN3K@201174|Actinobacteria,4CQHV@84995|Rubrobacteria	84995|Rubrobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158512_k127_3062448_0	266117.Rxyl_1805	9.756e-210	664.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158512_k127_3062448_1	266117.Rxyl_1511	2.624e-166	527.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CPBK@84995|Rubrobacteria	84995|Rubrobacteria	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158512_k127_3062448_5	266117.Rxyl_1512	1.692e-45	173.0	COG1610@1|root,COG1610@2|Bacteria,2IFFJ@201174|Actinobacteria,4CQJX@84995|Rubrobacteria	84995|Rubrobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158512_k127_3062448_6	292459.STH513	1.222e-32	136.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158512_k127_3062448_4	266117.Rxyl_1513	7.624e-70	246.0	COG1385@1|root,COG1385@2|Bacteria	2|Bacteria	J	rRNA (uridine-N3-)-methyltransferase activity	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SRR25158512_k127_3062448_2	266117.Rxyl_1514	1.831e-158	507.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CP6R@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158512_k127_3062448_3	42256.RradSPS_1522	5.453e-140	452.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CP6H@84995|Rubrobacteria	84995|Rubrobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SRR25158512_k127_308950_6	266117.Rxyl_1636	1.535e-48	176.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CPCY@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158512_k127_308950_5	266117.Rxyl_1637	5.734e-50	181.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158512_k127_308950_1	266117.Rxyl_1638	4.778e-254	793.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CP9Y@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158512_k127_308950_2	42256.RradSPS_1580	2.77e-118	386.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CPD1@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158512_k127_308950_0	42256.RradSPS_1581	1.519e-267	839.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CP6C@84995|Rubrobacteria	84995|Rubrobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158512_k127_308950_3	42256.RradSPS_1582	4.187e-70	243.0	COG0712@1|root,COG0712@2|Bacteria,2HNXP@201174|Actinobacteria,4CQ6B@84995|Rubrobacteria	84995|Rubrobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158512_k127_308950_4	266117.Rxyl_1642	1.121e-66	234.0	COG0711@1|root,COG0711@2|Bacteria,2HGFF@201174|Actinobacteria,4CQKE@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158512_k127_308950_8	266117.Rxyl_1643	9.948e-30	120.0	COG0636@1|root,COG0636@2|Bacteria,2HPGR@201174|Actinobacteria,4CQV2@84995|Rubrobacteria	84995|Rubrobacteria	C	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158512_k127_308950_7	266117.Rxyl_1644	5.564e-46	168.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CQG3@84995|Rubrobacteria	84995|Rubrobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158512_k127_3099791_4	42256.RradSPS_2356	4.723e-79	276.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N,SbcCD_C
SRR25158512_k127_3099791_1	42256.RradSPS_2355	1.131e-139	454.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
SRR25158512_k127_3099791_7	649638.Trad_0710	8.109e-28	117.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3099791_8	671143.DAMO_0711	1.3e-27	113.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
SRR25158512_k127_3099791_6	42256.RradSPS_2354	3.327e-61	214.0	COG4405@1|root,COG4405@2|Bacteria,2IKQP@201174|Actinobacteria	201174|Actinobacteria	I	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158512_k127_3099791_0	42256.RradSPS_2353	6.403e-321	993.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
SRR25158512_k127_3099791_2	266117.Rxyl_0453	1.413e-127	418.0	COG2380@1|root,COG2380@2|Bacteria	2|Bacteria	NU	COGs COG2380 conserved	-	-	-	ko:K09785	-	-	-	-	ko00000	-	-	-	NurA
SRR25158512_k127_3099791_3	266117.Rxyl_0455	2.881e-92	306.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CQCU@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158512_k127_3106208_0	266117.Rxyl_2358	4.559e-225	708.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CPQT@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-dependent synthetase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158512_k127_3106208_3	266117.Rxyl_2970	1.362e-62	231.0	COG1876@1|root,COG1876@2|Bacteria,2IN2C@201174|Actinobacteria,4CTKG@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
SRR25158512_k127_3106208_2	42256.RradSPS_2049	3.93e-72	245.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158512_k127_3106208_5	504728.K649_06950	1.263e-45	176.0	COG0454@1|root,COG0456@2|Bacteria,1WMYB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_3106208_1	42256.RradSPS_2577	3.495e-169	542.0	COG2059@1|root,COG2059@2|Bacteria,2IB69@201174|Actinobacteria	201174|Actinobacteria	P	chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158512_k127_3106208_8	512565.AMIS_46940	1.043e-26	123.0	COG4275@1|root,COG4275@2|Bacteria,2IPJU@201174|Actinobacteria,4DJAJ@85008|Micromonosporales	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3106208_6	1206739.BAGJ01000088_gene276	3.468e-38	147.0	COG4275@1|root,COG4275@2|Bacteria,2IK0B@201174|Actinobacteria,4G3EW@85025|Nocardiaceae	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158512_k127_3106208_4	871968.DESME_07100	4.664e-56	205.0	COG1117@1|root,COG1117@2|Bacteria,1V2UH@1239|Firmicutes,24BYG@186801|Clostridia,265B1@186807|Peptococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.55	ko:K02068,ko:K06857	ko02010,map02010	M00186,M00211	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
SRR25158512_k127_3106208_7	1183438.GKIL_2541	2.86e-27	116.0	COG0390@1|root,COG0390@2|Bacteria,1G1TY@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0014)	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158512_k127_3117896_2	266117.Rxyl_0551	3.725e-98	323.0	COG1028@1|root,COG1028@2|Bacteria,2GNM4@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158512_k127_3117896_0	266117.Rxyl_0550	9.001e-173	547.0	COG1879@1|root,COG1879@2|Bacteria,2ICHZ@201174|Actinobacteria,4CPBZ@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
SRR25158512_k127_3117896_1	266117.Rxyl_0549	6.896e-106	354.0	COG1172@1|root,COG1172@2|Bacteria,2IAN6@201174|Actinobacteria,4CQ68@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158512_k127_3117896_3	266117.Rxyl_0548	5.543e-68	239.0	COG1129@1|root,COG1129@2|Bacteria,2IC7X@201174|Actinobacteria,4CPP9@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158512_k127_3120134_0	266117.Rxyl_0698	2.337e-142	455.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria,4CQE8@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158512_k127_3120134_1	266117.Rxyl_0697	5.928e-75	261.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,4CTN9@84995|Rubrobacteria	84995|Rubrobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158512_k127_3124487_1	3075.A0A087SEE8	1.524e-19	87.0	COG0605@1|root,KOG0876@2759|Eukaryota	2759|Eukaryota	P	oxidoreductase activity, acting on superoxide radicals as acceptor	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158512_k127_3124487_0	42256.RradSPS_2758	3.229e-50	186.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158512_k127_3124831_0	42256.RradSPS_2498	5.978e-201	661.0	COG2197@1|root,COG2202@1|root,COG4585@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CT8E@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158512_k127_3124831_1	266117.Rxyl_3060	4.641e-147	473.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	crtL	-	5.5.1.18,5.5.1.19	ko:K06443,ko:K06444	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06960,R06962,R06963,R07840,R07856	RC01004,RC01612,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
SRR25158512_k127_3124831_2	67267.JNXT01000014_gene260	5.497e-82	278.0	28SI0@1|root,2ZEUB@2|Bacteria,2GNT0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
SRR25158512_k127_3124831_6	1463854.JOHT01000019_gene4850	1.03e-12	73.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SRR25158512_k127_3124831_4	266117.Rxyl_2114	1.91e-58	215.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4CS0X@84995|Rubrobacteria	201174|Actinobacteria	P	PFAM sulfatase	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
SRR25158512_k127_3124831_3	266117.Rxyl_1540	1.082e-81	285.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CPSE@84995|Rubrobacteria	84995|Rubrobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158512_k127_3124831_5	266117.Rxyl_1538	2.05e-25	107.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CPX5@84995|Rubrobacteria	84995|Rubrobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158512_k127_3124859_0	266117.Rxyl_1602	5.149e-134	430.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CQ0N@84995|Rubrobacteria	84995|Rubrobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158512_k127_3124859_2	1121355.KB903379_gene745	4.378e-08	56.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158512_k127_3124859_1	485913.Krac_0013	3.171e-110	368.0	COG4805@1|root,COG4805@2|Bacteria,2G8D3@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3135757_3	483218.BACPEC_00082	9.783e-20	91.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,269RA@186813|unclassified Clostridiales	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158512_k127_3135757_0	42256.RradSPS_1462	3.002e-137	444.0	COG0142@1|root,COG0142@2|Bacteria,2GN1P@201174|Actinobacteria,4CP7H@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158512_k127_3135757_1	266117.Rxyl_1455	8.039e-95	317.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CQ7R@84995|Rubrobacteria	84995|Rubrobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158512_k127_3135757_2	42256.RradSPS_1460	2.39e-44	166.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CPFG@84995|Rubrobacteria	84995|Rubrobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158512_k127_3162569_0	1077972.ARGLB_083_00800	9.097e-55	201.0	COG1266@1|root,COG1266@2|Bacteria,2HVFD@201174|Actinobacteria,1WBSF@1268|Micrococcaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158512_k127_3162569_2	512565.AMIS_41530	5.186e-13	74.0	2DQPU@1|root,337ZH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3162569_1	234267.Acid_3617	4.297e-40	163.0	COG4758@1|root,COG4758@2|Bacteria,3Y7Z2@57723|Acidobacteria	57723|Acidobacteria	S	N-terminal domain of toast_rack, DUF2154	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
SRR25158512_k127_3164951_2	266117.Rxyl_1487	1.082e-92	315.0	COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CQAV@84995|Rubrobacteria	84995|Rubrobacteria	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158512_k127_3164951_3	266117.Rxyl_1488	2.204e-88	301.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CQFG@84995|Rubrobacteria	84995|Rubrobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158512_k127_3164951_0	266117.Rxyl_1489	2.394e-198	621.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CP7W@84995|Rubrobacteria	84995|Rubrobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158512_k127_3164951_1	266117.Rxyl_1490	2.513e-128	415.0	COG0849@1|root,COG0849@2|Bacteria	2|Bacteria	D	cell division	ftsA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	DUF3484,FtsA,SHS2_FTSA
SRR25158512_k127_3168649_2	42256.RradSPS_1484	5.52e-169	537.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CPEA@84995|Rubrobacteria	84995|Rubrobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158512_k127_3168649_1	42256.RradSPS_1485	3.188e-193	608.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CP5S@84995|Rubrobacteria	84995|Rubrobacteria	EF	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158512_k127_3168649_0	266117.Rxyl_1479	4.865e-209	672.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CPDG@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158512_k127_3168649_4	266117.Rxyl_1480	1.547e-135	437.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CPT1@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158512_k127_3168649_5	42256.RradSPS_1488	7.131e-85	285.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4CQBB@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158512_k127_3168649_3	234621.RER_26210	1.604e-148	482.0	COG0477@1|root,COG2814@2|Bacteria,2GM2G@201174|Actinobacteria,4FXUX@85025|Nocardiaceae	201174|Actinobacteria	EGP	Protein involved in sugar porter activity, transport and response to antibiotic	pcaK	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4,Sugar_tr
SRR25158512_k127_3176997_2	234267.Acid_7807	0.0004135	46.0	COG0726@1|root,COG0726@2|Bacteria,3Y95Z@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158512_k127_3176997_0	1536774.H70357_09545	5.451e-218	692.0	COG3250@1|root,COG3250@2|Bacteria,1TQAM@1239|Firmicutes,4HB7S@91061|Bacilli,26SR5@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158512_k127_3176997_1	485913.Krac_5013	4.012e-124	409.0	COG1653@1|root,COG1653@2|Bacteria,2G8P0@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
SRR25158512_k127_3177719_0	42256.RradSPS_0448	2.628e-307	945.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CPHH@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158512_k127_3177719_1	42256.RradSPS_0454	4.581e-276	858.0	COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria,4CP7I@84995|Rubrobacteria	84995|Rubrobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158512_k127_3177719_5	42256.RradSPS_0458	5.709e-84	280.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CQ04@84995|Rubrobacteria	84995|Rubrobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158512_k127_3177719_3	42256.RradSPS_2830	1.037e-132	438.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07506,ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC,Response_reg
SRR25158512_k127_3177719_8	1459636.NTE_00024	5.491e-13	74.0	COG5485@1|root,arCOG06513@2157|Archaea	2157|Archaea	S	ester cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
SRR25158512_k127_3177719_2	479432.Sros_0756	2.445e-196	625.0	COG0477@1|root,COG0477@2|Bacteria,2I3G4@201174|Actinobacteria,4EGQ0@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_3177719_6	1122919.KB905629_gene39	4.374e-76	271.0	COG1748@1|root,COG1748@2|Bacteria,1V1T1@1239|Firmicutes,4HG5Q@91061|Bacilli,26SRA@186822|Paenibacillaceae	91061|Bacilli	E	Saccharopine dehydrogenase	lyS1	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158512_k127_3177719_11	13035.Dacsa_0329	8.172e-05	47.0	COG3415@1|root,COG3415@2|Bacteria,1G8B4@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_Tnp_IS630
SRR25158512_k127_3187984_1	1245475.ANAE01000140_gene4497	3.067e-104	355.0	COG2141@1|root,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_3187984_0	266117.Rxyl_1058	3.536e-136	449.0	COG0477@1|root,COG0477@2|Bacteria,2I2QX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08168,ko:K18926	-	M00704,M00715	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.16,2.A.1.3.22,2.A.1.3.30,2.A.1.3.6	-	-	MFS_1
SRR25158512_k127_3190045_1	266117.Rxyl_0036	3.159e-236	737.0	COG0439@1|root,COG0439@2|Bacteria,2I2S0@201174|Actinobacteria,4CP7I@84995|Rubrobacteria	201174|Actinobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
SRR25158512_k127_3190045_5	266117.Rxyl_0035	2.894e-50	193.0	COG0511@1|root,COG0511@2|Bacteria,2IR3V@201174|Actinobacteria	201174|Actinobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	4.1.1.3	ko:K01571,ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00217,R00742	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158512_k127_3190045_0	266117.Rxyl_0034	1.798e-272	857.0	COG0323@1|root,COG0323@2|Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c,HATPase_c_3,MutL_C
SRR25158512_k127_3190045_3	42256.RradSPS_0035	3.979e-77	269.0	COG0697@1|root,COG0697@2|Bacteria,2ID9Z@201174|Actinobacteria,4CSCH@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_3190045_2	266117.Rxyl_0030	3.15e-187	591.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4CPB8@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158512_k127_3190045_6	266117.Rxyl_0029	1.357e-43	160.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4CQQR@84995|Rubrobacteria	84995|Rubrobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158512_k127_3190045_4	266117.Rxyl_0028	4.097e-64	225.0	2AVPF@1|root,31MGI@2|Bacteria,2HE2U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3192162_2	266117.Rxyl_2373	4.584e-26	111.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4CR8Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
SRR25158512_k127_3192162_0	266117.Rxyl_3119	6.641e-108	358.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4CQMB@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158512_k127_3192162_1	266117.Rxyl_3118	4.105e-83	280.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4CQ6N@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158512_k127_3194097_4	42256.RradSPS_2318	9.578e-08	55.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4CQTM@84995|Rubrobacteria	84995|Rubrobacteria	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158512_k127_3194097_5	1463858.JOHR01000024_gene4129	0.0001945	46.0	28RR8@1|root,2ZE3T@2|Bacteria	2|Bacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SRR25158512_k127_3194097_3	266117.Rxyl_2899	1.933e-58	211.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158512_k127_3194097_1	266117.Rxyl_2898	1.823e-194	617.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4CU2J@84995|Rubrobacteria	84995|Rubrobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_3194097_2	518766.Rmar_0581	5.401e-117	392.0	COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,1FIXW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the conversion of chorismate to isochorismate	entC	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158512_k127_3194097_0	266117.Rxyl_2896	2.836e-211	672.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4CPYA@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRR25158512_k127_3203107_1	266117.Rxyl_1625	4.706e-189	599.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CPJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158512_k127_3203107_2	266117.Rxyl_1624	1.529e-176	559.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4CPFB@84995|Rubrobacteria	84995|Rubrobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158512_k127_3203107_4	266117.Rxyl_1623	2.108e-78	269.0	COG1040@1|root,COG1040@2|Bacteria,2HP3J@201174|Actinobacteria,4CQES@84995|Rubrobacteria	84995|Rubrobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158512_k127_3203107_3	266117.Rxyl_1622	1.488e-87	292.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CQU6@84995|Rubrobacteria	84995|Rubrobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158512_k127_3203107_0	266117.Rxyl_1621	0.0	1056.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CPGC@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158512_k127_3205363_4	1218352.B597_012185	8.024e-19	97.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria,1Z0RX@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158512_k127_3205363_0	42256.RradSPS_2067	4.569e-79	267.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CT6D@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158512_k127_3205363_2	42256.RradSPS_2066	7.016e-66	228.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4CQ9H@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158512_k127_3205363_3	266117.Rxyl_2372	1.647e-20	91.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4CQ9H@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158512_k127_3205363_1	42256.RradSPS_2508	1.372e-73	252.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4CSZP@84995|Rubrobacteria	84995|Rubrobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158512_k127_3205363_5	1380370.JIBA01000015_gene125	2.312e-13	73.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4FEA5@85021|Intrasporangiaceae	201174|Actinobacteria	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
SRR25158512_k127_3205478_2	266117.Rxyl_0421	1.414e-16	79.0	COG2879@1|root,COG2879@2|Bacteria	2|Bacteria	S	small protein	ybdD	-	-	-	-	-	-	-	-	-	-	-	Sel_put
SRR25158512_k127_3205478_0	266117.Rxyl_0416	1.498e-129	423.0	COG1120@1|root,COG1120@2|Bacteria,2GJ49@201174|Actinobacteria,4CP89@84995|Rubrobacteria	84995|Rubrobacteria	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158512_k127_3205478_1	1128421.JAGA01000002_gene1784	1.055e-20	100.0	COG4114@1|root,COG4114@2|Bacteria,2NRDP@2323|unclassified Bacteria	2|Bacteria	S	FhuF 2Fe-2S C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FhuF,FhuF_C
SRR25158512_k127_3209835_3	1502851.FG93_03307	4.325e-32	130.0	COG1028@1|root,COG1028@2|Bacteria,1QKCK@1224|Proteobacteria,2UAID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_3209835_0	266117.Rxyl_3020	2.259e-123	404.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4CSYJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158512_k127_3209835_4	266117.Rxyl_3021	1.785e-12	70.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA,TonB_dep_Rec
SRR25158512_k127_3209835_2	266117.Rxyl_3022	8.834e-61	217.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TerC
SRR25158512_k127_3209835_1	266117.Rxyl_3053	1.714e-92	311.0	COG0530@1|root,COG0530@2|Bacteria,2IA02@201174|Actinobacteria	201174|Actinobacteria	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158512_k127_3216346_5	1121472.AQWN01000001_gene131	0.0002695	49.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia,2612Z@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyltransferase family 28 C-terminal domain	ugtP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
SRR25158512_k127_3216346_2	266117.Rxyl_1313	1.653e-39	150.0	COG1734@1|root,COG1734@2|Bacteria,2HRXB@201174|Actinobacteria,4CU0F@84995|Rubrobacteria	84995|Rubrobacteria	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158512_k127_3216346_1	469383.Cwoe_4579	2.779e-52	196.0	COG1994@1|root,COG1994@2|Bacteria,2H6BD@201174|Actinobacteria,4CS7E@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3216346_0	266117.Rxyl_1314	1.065e-186	589.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4CPDY@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158512_k127_3216346_4	266117.Rxyl_1316	5.972e-13	70.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CPM6@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158512_k127_3234052_3	266117.Rxyl_1222	8.078e-13	72.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	CP_0762	-	-	-	-	-	-	-	-	-	-	-	Apolipoprotein,DUF1978
SRR25158512_k127_3234052_2	266117.Rxyl_1224	4.655e-65	226.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158512_k127_3234052_0	42256.RradSPS_1189	1.022e-184	594.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria	201174|Actinobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158512_k127_3234052_1	266117.Rxyl_1226	1.215e-104	345.0	COG2271@1|root,COG2271@2|Bacteria,2I4BI@201174|Actinobacteria,4CPZW@84995|Rubrobacteria	84995|Rubrobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRR25158512_k127_3238779_0	266117.Rxyl_2663	3.333e-61	229.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2I2Y1@201174|Actinobacteria,4CU6E@84995|Rubrobacteria	201174|Actinobacteria	T	PFAM response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like Hpt PAS fold-3 PAS fold-4 PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
SRR25158512_k127_3238779_1	1235457.C404_03565	4.351e-27	119.0	28WUQ@1|root,2ZIU4@2|Bacteria,1P7TM@1224|Proteobacteria,2W7CR@28216|Betaproteobacteria,1KEBR@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3254865_1	266117.Rxyl_2888	2.999e-140	452.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CPWH@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158512_k127_3254865_3	266117.Rxyl_2887	1.366e-104	346.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CPHD@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158512_k127_3254865_2	292459.STH2890	1.917e-119	396.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158512_k127_3254865_0	266117.Rxyl_2885	1.061e-165	526.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CPXE@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158512_k127_3254865_4	266117.Rxyl_2884	1.947e-75	255.0	COG1438@1|root,COG1438@2|Bacteria	2|Bacteria	K	arginine binding	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158512_k127_3286144_5	266117.Rxyl_1970	2.949e-38	148.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	nrfG	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0065003,GO:0071704,GO:0071840,GO:1901564	-	ko:K02200,ko:K04018	-	-	-	-	ko00000	-	-	-	CcmH,TPR_16,TPR_2,Trypsin_2
SRR25158512_k127_3286144_7	518766.Rmar_2500	1.615e-10	65.0	COG1826@1|root,COG1826@2|Bacteria,4PETH@976|Bacteroidetes,1FJKH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158512_k127_3286144_3	266117.Rxyl_1968	8.585e-110	362.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CP82@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158512_k127_3286144_9	1132509.C447_07073	4.044e-06	55.0	arCOG02899@1|root,arCOG02899@2157|Archaea,2XX38@28890|Euryarchaeota,23VPR@183963|Halobacteria	183963|Halobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158512_k127_3286144_1	266117.Rxyl_1967	1.935e-121	396.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CQ7T@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158512_k127_3286144_0	266117.Rxyl_1966	6.814e-135	435.0	COG0382@1|root,COG0382@2|Bacteria,2GJ6P@201174|Actinobacteria,4CTED@84995|Rubrobacteria	84995|Rubrobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158512_k127_3286144_2	266117.Rxyl_1965	2.376e-121	402.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158512_k127_3286144_6	42256.RradSPS_0310	2.958e-26	119.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158512_k127_3286144_4	42256.RradSPS_2232	2.216e-92	318.0	COG2271@1|root,COG2271@2|Bacteria,2I39P@201174|Actinobacteria	201174|Actinobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158512_k127_3286144_8	591158.SSMG_05146	2.732e-06	59.0	COG1476@1|root,COG1476@2|Bacteria,2IFSD@201174|Actinobacteria	2|Bacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158512_k127_3288950_3	42256.RradSPS_1275	5.95e-92	306.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CPK9@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158512_k127_3288950_5	266117.Rxyl_1299	3.417e-52	196.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158512_k127_3288950_1	266117.Rxyl_1298	4.56e-157	504.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4CPGZ@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,PHP_C
SRR25158512_k127_3288950_0	42256.RradSPS_1271	5.105e-194	607.0	COG0473@1|root,COG0473@2|Bacteria,2IAD3@201174|Actinobacteria,4CU2H@84995|Rubrobacteria	84995|Rubrobacteria	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158512_k127_3288950_4	42256.RradSPS_1270	1.991e-55	203.0	COG2881@1|root,COG2881@2|Bacteria	2|Bacteria	M	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
SRR25158512_k127_3294451_18	266117.Rxyl_0887	7.192e-22	95.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4CQUG@84995|Rubrobacteria	84995|Rubrobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2,PLDc_N
SRR25158512_k127_3294451_20	1336243.JAEA01000001_gene1813	6.735e-06	53.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HCBP_related,HemolysinCabind,VWA_2
SRR25158512_k127_3294451_0	42256.RradSPS_0780	1.119e-258	807.0	COG0608@1|root,COG0608@2|Bacteria,2IK2U@201174|Actinobacteria,4CPI9@84995|Rubrobacteria	84995|Rubrobacteria	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158512_k127_3294451_2	266117.Rxyl_0889	3.065e-137	443.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158512_k127_3294451_7	266117.Rxyl_0890	6.534e-112	366.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CQ57@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158512_k127_3294451_6	266117.Rxyl_0891	2.903e-113	371.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CPR6@84995|Rubrobacteria	84995|Rubrobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158512_k127_3294451_8	266117.Rxyl_0892	4.812e-107	352.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CPN8@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158512_k127_3294451_11	42256.RradSPS_0785	6.48e-82	282.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CQ1I@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158512_k127_3294451_4	1464048.JNZS01000004_gene1388	1.401e-122	408.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4D8CT@85008|Micromonosporales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158512_k127_3294451_1	42256.RradSPS_0787	2.601e-161	515.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CPAI@84995|Rubrobacteria	84995|Rubrobacteria	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158512_k127_3294451_10	266117.Rxyl_0896	8.982e-83	281.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CQ60@84995|Rubrobacteria	84995|Rubrobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158512_k127_3294451_12	266117.Rxyl_0897	1.705e-72	252.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CQJ6@84995|Rubrobacteria	84995|Rubrobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158512_k127_3294451_13	35754.JNYJ01000062_gene1479	4.878e-39	158.0	COG4122@1|root,COG4122@2|Bacteria,2GJCJ@201174|Actinobacteria,4DF5B@85008|Micromonosporales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158512_k127_3294451_5	479431.Namu_0278	2.719e-116	387.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4EU45@85013|Frankiales	201174|Actinobacteria	M	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158512_k127_3294451_3	42256.RradSPS_0790	1.348e-127	415.0	COG1725@1|root,COG1725@2|Bacteria,2I4BB@201174|Actinobacteria,4CTS5@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein, gntR	-	-	-	-	-	-	-	-	-	-	-	-	GntR
SRR25158512_k127_3294451_9	42256.RradSPS_0792	1.953e-94	314.0	COG1296@1|root,COG1296@2|Bacteria,2HQM2@201174|Actinobacteria,4CS6P@84995|Rubrobacteria	84995|Rubrobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158512_k127_3294451_17	42256.RradSPS_0793	1.261e-22	102.0	COG4541@1|root,COG4541@2|Bacteria	2|Bacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158512_k127_3294451_16	396513.SCA_0337	4.081e-34	140.0	COG0586@1|root,COG0586@2|Bacteria,1V1D4@1239|Firmicutes,4HFSU@91061|Bacilli	91061|Bacilli	S	membrane-associated protein	yngC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158512_k127_3294451_15	873449.STRCR_1211	2.552e-36	151.0	COG0726@1|root,COG0726@2|Bacteria,1V4PK@1239|Firmicutes,4HHZI@91061|Bacilli	91061|Bacilli	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158512_k127_3294451_19	1123037.AUDE01000039_gene2697	2.006e-10	66.0	COG0076@1|root,COG0076@2|Bacteria,4NGZB@976|Bacteroidetes,1HZDC@117743|Flavobacteriia	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158512_k127_3296512_1	266117.Rxyl_0186	3.874e-135	443.0	COG0642@1|root,COG2205@2|Bacteria,2H8CD@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158512_k127_3296512_2	266117.Rxyl_0187	1.185e-100	333.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CQ94@84995|Rubrobacteria	84995|Rubrobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_3296512_4	42256.RradSPS_2302	4.924e-57	204.0	29WF5@1|root,30I10@2|Bacteria,2HRPZ@201174|Actinobacteria,4CTS7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3296512_5	266117.Rxyl_0142	3.956e-52	189.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4CQIW@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158512_k127_3296512_6	1304275.C41B8_04066	3.419e-21	99.0	COG1403@1|root,COG1403@2|Bacteria,1N1B4@1224|Proteobacteria,1SF8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3296512_3	42256.RradSPS_2584	3.757e-60	213.0	COG1247@1|root,COG1247@2|Bacteria,2HU9F@201174|Actinobacteria,4CTVS@84995|Rubrobacteria	84995|Rubrobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158512_k127_3296512_0	266117.Rxyl_0143	1.068e-221	697.0	COG4147@1|root,COG4147@2|Bacteria,2GJ56@201174|Actinobacteria,4CPD8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158512_k127_3298910_2	1382306.JNIM01000001_gene1704	5.622e-08	57.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158512_k127_3298910_0	1089546.AQUI01000002_gene1424	5.903e-201	640.0	COG1292@1|root,COG1292@2|Bacteria,2GJX0@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
SRR25158512_k127_3298910_1	42256.RradSPS_2076	4.908e-90	308.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4CS26@84995|Rubrobacteria	84995|Rubrobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158512_k127_3305301_3	42256.RradSPS_3049	5.85e-14	72.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CST2@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_3305301_0	42256.RradSPS_3048	2.6e-129	428.0	COG5002@1|root,COG5002@2|Bacteria,2I4C4@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase- DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158512_k127_3305301_5	1121346.KB899822_gene2943	2.514e-07	55.0	2DT9X@1|root,33JCU@2|Bacteria,1W170@1239|Firmicutes,4HYRK@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF5049)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5049
SRR25158512_k127_3305301_2	479434.Sthe_0398	4.719e-59	213.0	COG0730@1|root,COG0730@2|Bacteria,2G6RC@200795|Chloroflexi	200795|Chloroflexi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158512_k127_3305301_4	266117.Rxyl_0100	9.533e-12	74.0	COG3883@1|root,COG3883@2|Bacteria,2I4Y8@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3305301_1	42256.RradSPS_1061	3.046e-119	386.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,4CP96@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
SRR25158512_k127_3310998_1	471852.Tcur_2255	8.541e-129	416.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4EGS8@85012|Streptosporangiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-associated	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158512_k127_3310998_0	463191.SSEG_09935	4.934e-137	445.0	COG2159@1|root,COG2159@2|Bacteria,2GNF3@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158512_k127_3310998_4	463191.SSEG_09936	1.169e-29	124.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	MA20_19305	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158512_k127_3310998_3	266117.Rxyl_0509	7.691e-44	164.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,4CQFN@84995|Rubrobacteria	84995|Rubrobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158512_k127_3310998_2	266117.Rxyl_0510	1.294e-86	287.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CQ0D@84995|Rubrobacteria	84995|Rubrobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158512_k127_3313967_1	1118054.CAGW01000005_gene3791	5.165e-90	312.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158512_k127_3313967_0	266117.Rxyl_1582	9.472e-174	549.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPIQ@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158512_k127_3320616_2	266117.Rxyl_0039	1.646e-65	227.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4CPXG@84995|Rubrobacteria	84995|Rubrobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158512_k127_3320616_3	1246995.AFR_11315	1.643e-59	213.0	COG2085@1|root,COG2085@2|Bacteria,2GP3E@201174|Actinobacteria	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	-
SRR25158512_k127_3320616_1	316274.Haur_1523	2.064e-81	282.0	2F63Z@1|root,33YN9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3320616_6	1079986.JH164837_gene5938	6.34e-25	108.0	COG4274@1|root,COG4274@2|Bacteria,2IN0N@201174|Actinobacteria	201174|Actinobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
SRR25158512_k127_3320616_0	266117.Rxyl_0679	7.514e-170	548.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4CQUG@84995|Rubrobacteria	84995|Rubrobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRR25158512_k127_3320616_5	266117.Rxyl_0165	2.478e-40	153.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria	201174|Actinobacteria	C	Suf system fes assembly protein, nifu family	sufU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158512_k127_3320616_4	515635.Dtur_0361	2.741e-56	216.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158512_k127_3325343_0	42256.RradSPS_3020	1.612e-95	319.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CPE7@84995|Rubrobacteria	84995|Rubrobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158512_k127_3325343_2	42256.RradSPS_1296	1.301e-16	83.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4CTQS@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158512_k127_3326340_0	42256.RradSPS_3045	2.584e-247	778.0	COG0823@1|root,COG0823@2|Bacteria,2I4C3@201174|Actinobacteria,4CQSU@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3326340_2	562970.Btus_0614	1.415e-173	555.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,278QI@186823|Alicyclobacillaceae	91061|Bacilli	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158512_k127_3326340_3	266117.Rxyl_2370	9.327e-129	417.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4CQ58@84995|Rubrobacteria	84995|Rubrobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158512_k127_3326340_1	1151118.KB895809_gene2124	4.904e-221	699.0	COG0366@1|root,COG0366@2|Bacteria,2GKK1@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
SRR25158512_k127_333047_1	266117.Rxyl_0039	7.452e-92	310.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4CPXG@84995|Rubrobacteria	84995|Rubrobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158512_k127_333047_0	525904.Tter_0452	2.242e-103	342.0	COG1028@1|root,COG1028@2|Bacteria	525904.Tter_0452|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR25158512_k127_333047_3	2045.KR76_22095	2.513e-65	242.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,2HQ9W@201174|Actinobacteria,4DRST@85009|Propionibacteriales	201174|Actinobacteria	MO	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_333047_2	266117.Rxyl_3171	6.4e-78	268.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4CR8Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
SRR25158512_k127_3344296_1	1032480.MLP_40150	1.133e-67	242.0	COG0596@1|root,COG0596@2|Bacteria,2IAVM@201174|Actinobacteria,4DTDH@85009|Propionibacteriales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158512_k127_3344296_4	146922.JOFU01000090_gene6194	7.543e-05	51.0	COG1476@1|root,COG1476@2|Bacteria,2IFSD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158512_k127_3344296_0	1193181.BN10_140060	4.762e-88	296.0	COG1247@1|root,COG1247@2|Bacteria,2II0A@201174|Actinobacteria,4FGIY@85021|Intrasporangiaceae	201174|Actinobacteria	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_3344296_3	1089551.KE386572_gene3899	4.421e-12	75.0	COG1787@1|root,COG1787@2|Bacteria,1MZWS@1224|Proteobacteria,2UE03@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
SRR25158512_k127_3349048_0	266117.Rxyl_2944	5.604e-160	512.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,4CQKV@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158512_k127_3349048_2	1230476.C207_00154	2.562e-73	261.0	COG0500@1|root,COG2226@2|Bacteria,1N4AC@1224|Proteobacteria,2VFE9@28211|Alphaproteobacteria,3JZG2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_3349048_1	266117.Rxyl_2910	7.053e-84	281.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
SRR25158512_k127_3350108_4	696281.Desru_3837	3.312e-98	337.0	COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,24ZI2@186801|Clostridia,26447@186807|Peptococcaceae	186801|Clostridia	C	CoA-ligase	-	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	Ligase_CoA
SRR25158512_k127_3350108_3	696281.Desru_3836	1.024e-130	426.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,249ED@186801|Clostridia,264U3@186807|Peptococcaceae	186801|Clostridia	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158512_k127_3350108_1	138119.DSY0244	4.532e-199	630.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia,2640E@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	-	-	1.2.1.10,1.2.1.81	ko:K00132,ko:K15515	ko00620,ko00650,ko01100,ko01120,map00620,map00650,map01100,map01120	-	R00228,R01172	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158512_k127_3350108_0	1211814.CAPG01000056_gene2778	8.597e-274	853.0	COG0028@1|root,COG0028@2|Bacteria,1TSBQ@1239|Firmicutes,4HDM6@91061|Bacilli,1ZEW0@1386|Bacillus	91061|Bacilli	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158512_k127_3350108_2	266117.Rxyl_2381	5.198e-179	571.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CPCX@84995|Rubrobacteria	84995|Rubrobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158512_k127_3350108_5	485913.Krac_2585	3.682e-74	254.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158512_k127_3377077_4	42256.RradSPS_2285	8.338e-50	185.0	COG0457@1|root,COG0457@2|Bacteria	42256.RradSPS_2285|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3377077_1	266117.Rxyl_2867	3.398e-89	297.0	COG4293@1|root,COG4293@2|Bacteria,2IG98@201174|Actinobacteria,4CQEX@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
SRR25158512_k127_3377077_0	266117.Rxyl_2866	1.13e-227	712.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CPK3@84995|Rubrobacteria	84995|Rubrobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158512_k127_3377077_2	2074.JNYD01000034_gene6451	8.067e-60	216.0	COG0500@1|root,COG2226@2|Bacteria,2I3SP@201174|Actinobacteria,4EB4F@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158512_k127_3377077_5	234621.RER_56990	7.935e-35	138.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4FWFN@85025|Nocardiaceae	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158512_k127_3377077_6	356851.JOAN01000021_gene2372	4.141e-15	81.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4DBU7@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158512_k127_3377077_3	1389489.O159_04790	6.093e-57	205.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4FKF3@85023|Microbacteriaceae	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158512_k127_3377077_7	446469.Sked_00550	8.536e-10	63.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	yqjI	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_3385_0	42256.RradSPS_2422	2.527e-117	381.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CU2Q@84995|Rubrobacteria	201174|Actinobacteria	K	Response regulator receiver	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_3385_1	266117.Rxyl_2782	7.598e-114	371.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CU1T@84995|Rubrobacteria	84995|Rubrobacteria	F	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
SRR25158512_k127_3385_2	395961.Cyan7425_3017	3.362e-22	103.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,3KH7P@43988|Cyanothece	1117|Cyanobacteria	T	Multi-sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4
SRR25158512_k127_3387723_5	1122609.AUGT01000002_gene3998	1.884e-32	129.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4DNUK@85009|Propionibacteriales	201174|Actinobacteria	E	Polar amino acid transport system	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
SRR25158512_k127_3387723_4	1265505.ATUG01000001_gene4315	2.031e-69	243.0	COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,42NEI@68525|delta/epsilon subdivisions,2WJP9@28221|Deltaproteobacteria,2MJ3S@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
SRR25158512_k127_3387723_2	1122609.AUGT01000002_gene3996	1.455e-92	312.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158512_k127_3387723_0	234267.Acid_7336	3.113e-169	549.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158512_k127_3387723_3	1121272.KB903249_gene2330	6.618e-89	303.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria,4DB1Y@85008|Micromonosporales	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158512_k127_3387723_1	42256.RradSPS_0483	2.188e-122	400.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria,4CPDS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
SRR25158512_k127_3403243_11	1380391.JIAS01000013_gene3519	1.182e-34	138.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JQQC@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158512_k127_3403243_9	266117.Rxyl_0698	2.696e-41	158.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria,4CQE8@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158512_k127_3403243_6	1380391.JIAS01000013_gene3518	4.406e-104	347.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,2JQ7X@204441|Rhodospirillales	204441|Rhodospirillales	E	COG1177 ABC-type spermidine putrescine transport system, permease component II	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158512_k127_3403243_7	1380391.JIAS01000013_gene3517	3.101e-102	342.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,2JQTE@204441|Rhodospirillales	204441|Rhodospirillales	E	Putrescine transport system permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158512_k127_3403243_8	318424.EU78_02890	1.932e-100	342.0	COG0687@1|root,COG0687@2|Bacteria,2IBEC@201174|Actinobacteria,234YK@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
SRR25158512_k127_3403243_10	931627.MycrhDRAFT_3646	3.415e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,2GNDM@201174|Actinobacteria,234I6@1762|Mycobacteriaceae	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158512_k127_3403243_0	246196.MSMEI_0647	6.837e-226	711.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,234PD@1762|Mycobacteriaceae	201174|Actinobacteria	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158512_k127_3403243_2	1380391.JIAS01000003_gene1909	2.819e-167	549.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2JV15@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158512_k127_3403243_3	246196.MSMEI_0640	4.717e-129	424.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria,236RV@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158512_k127_3403243_1	42256.RradSPS_2927	1.456e-196	619.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	FOXRED	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158512_k127_3403243_5	1380391.JIAS01000011_gene5426	2.146e-104	353.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_3403243_4	1380390.JIAT01000002_gene5962	6.219e-120	392.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPDT@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.19	ko:K00137	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R02549	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158512_k127_340492_1	3075.A0A087SEE8	1.695e-19	87.0	COG0605@1|root,KOG0876@2759|Eukaryota	2759|Eukaryota	P	oxidoreductase activity, acting on superoxide radicals as acceptor	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SRR25158512_k127_340492_0	266117.Rxyl_2921	1.167e-176	564.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4CU2M@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158512_k127_340492_2	42256.RradSPS_0321	2.588e-17	81.0	COG1012@1|root,COG1012@2|Bacteria,2GM5R@201174|Actinobacteria,4CPBR@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh
SRR25158512_k127_3408937_1	1459636.NTE_02825	2.2e-12	75.0	arCOG03383@1|root,arCOG03383@2157|Archaea	2157|Archaea	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158512_k127_3408937_0	477641.MODMU_1166	1.187e-50	190.0	COG1813@1|root,COG3903@1|root,COG1813@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EUW7@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,Trans_reg_C
SRR25158512_k127_3413405_0	1150399.AQYK01000001_gene1563	1.906e-205	648.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4FR96@85023|Microbacteriaceae	201174|Actinobacteria	P	Sulfatase	atsD	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158512_k127_3413405_2	266117.Rxyl_0679	1.675e-25	113.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4CQUG@84995|Rubrobacteria	84995|Rubrobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRR25158512_k127_3413405_3	710686.Mycsm_03589	1.45e-10	64.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3413405_1	47839.CCAU010000005_gene481	5.356e-122	419.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,2366A@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158512_k127_3414532_4	42256.RradSPS_2412	1.261e-27	115.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158512_k127_3414532_1	266117.Rxyl_2766	2.981e-128	419.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4CQ2X@84995|Rubrobacteria	84995|Rubrobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
SRR25158512_k127_3414532_3	266117.Rxyl_2765	2.288e-66	245.0	COG1443@1|root,COG1443@2|Bacteria,2HN6K@201174|Actinobacteria,4CQKF@84995|Rubrobacteria	84995|Rubrobacteria	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158512_k127_3414532_2	266117.Rxyl_0683	1.138e-67	241.0	2DBB1@1|root,2Z854@2|Bacteria,2GNBN@201174|Actinobacteria	201174|Actinobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
SRR25158512_k127_3414532_0	266117.Rxyl_2763	4.618e-285	884.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CQ32@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158512_k127_3414532_5	546414.Deide_15390	3.318e-17	92.0	COG4585@1|root,COG4585@2|Bacteria,1WM3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Sensor
SRR25158512_k127_3416381_7	304371.MCP_1902	5.403e-05	47.0	COG0589@1|root,arCOG02053@2157|Archaea,2XZV8@28890|Euryarchaeota	28890|Euryarchaeota	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_3416381_3	266117.Rxyl_3070	3.998e-77	269.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_3416381_0	42256.RradSPS_2794	5.882e-216	677.0	COG0446@1|root,COG0446@2|Bacteria,2HQQT@201174|Actinobacteria,4CSDR@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158512_k127_3416381_4	42256.RradSPS_2494	1.111e-64	234.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_3416381_6	1380393.JHVP01000004_gene579	3.997e-51	190.0	COG3371@1|root,COG3371@2|Bacteria,2H4EC@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158512_k127_3416381_5	266117.Rxyl_3085	1.478e-58	214.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_3416381_2	42256.RradSPS_2490	3.909e-91	313.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158512_k127_3416381_1	42256.RradSPS_3070	1.196e-100	341.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4CPT3@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158512_k127_3424222_0	266117.Rxyl_1340	8.411e-116	378.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CPRI@84995|Rubrobacteria	84995|Rubrobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158512_k127_3424222_1	266117.Rxyl_1341	5.566e-96	319.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CU5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158512_k127_3424222_2	1173026.Glo7428_3020	1.176e-48	177.0	COG2219@1|root,COG2219@2|Bacteria,1G7G7@1117|Cyanobacteria	1117|Cyanobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3424222_3	1341151.ASZU01000015_gene2046	1.467e-39	149.0	COG0346@1|root,COG0346@2|Bacteria,1V6FU@1239|Firmicutes,4HIRR@91061|Bacilli	91061|Bacilli	E	glyoxalase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158512_k127_3449507_0	266117.Rxyl_1235	8.174e-186	595.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158512_k127_3449507_1	266117.Rxyl_1236	2.882e-142	458.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,4CRA0@84995|Rubrobacteria	84995|Rubrobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158512_k127_3449507_3	1506583.JQJY01000005_gene2205	3.384e-12	70.0	COG4291@1|root,COG4291@2|Bacteria,4NNE5@976|Bacteroidetes,1I4N7@117743|Flavobacteriia,2NX0T@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SRR25158512_k127_3460380_4	266117.Rxyl_2472	0.0001133	44.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria	2|Bacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	ecfA	-	-	ko:K16784,ko:K16786,ko:K16787	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF87
SRR25158512_k127_3460380_2	266117.Rxyl_2473	1.297e-68	239.0	COG4684@1|root,COG4684@2|Bacteria	2|Bacteria	S	ECF transporter, substrate-specific component	panT	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
SRR25158512_k127_3460380_1	266117.Rxyl_2474	2.709e-121	397.0	COG1028@1|root,COG1028@2|Bacteria,2GP5U@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_3460380_0	266117.Rxyl_2475	1.947e-203	639.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4CRDS@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158512_k127_3460380_3	266117.Rxyl_2271	7.255e-56	198.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4CPP0@84995|Rubrobacteria	84995|Rubrobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158512_k127_3463137_2	266117.Rxyl_0756	5.488e-36	143.0	COG5542@1|root,COG5542@2|Bacteria,2HNS4@201174|Actinobacteria,4CPZM@84995|Rubrobacteria	84995|Rubrobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158512_k127_3463137_0	266117.Rxyl_1239	2.221e-164	546.0	COG4743@1|root,COG4743@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1616
SRR25158512_k127_3463137_1	266117.Rxyl_2114	2.072e-70	247.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4CS0X@84995|Rubrobacteria	201174|Actinobacteria	P	PFAM sulfatase	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
SRR25158512_k127_34714_2	266117.Rxyl_0695	1.238e-106	351.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria	201174|Actinobacteria	G	inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158512_k127_34714_0	266117.Rxyl_1125	3.474e-251	780.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CP7E@84995|Rubrobacteria	84995|Rubrobacteria	E	glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158512_k127_34714_4	266117.Rxyl_1126	7.079e-68	239.0	2BYAG@1|root,2ZC13@2|Bacteria,2IGUZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_34714_3	1492922.GY26_13025	1.427e-85	304.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,1RQ4S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	topoisomerase	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158512_k127_34714_1	266117.Rxyl_1127	1.86e-164	524.0	COG2170@1|root,COG2170@2|Bacteria,2H5B4@201174|Actinobacteria,4CQ42@84995|Rubrobacteria	84995|Rubrobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158512_k127_34714_6	1121380.JNIW01000058_gene11	2.655e-07	59.0	COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158512_k127_34714_5	42256.RradSPS_1125	6.764e-08	59.0	COG1767@1|root,COG1767@2|Bacteria,2H80Q@201174|Actinobacteria,4CTM7@84995|Rubrobacteria	84995|Rubrobacteria	H	ATP:dephospho-CoA triphosphoribosyl transferase	-	-	2.4.2.52	ko:K05966	ko02020,map02020	-	R09675	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG
SRR25158512_k127_3482961_2	1068980.ARVW01000001_gene3663	7.884e-12	68.0	COG3629@1|root,COG3629@2|Bacteria,2GTRT@201174|Actinobacteria	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158512_k127_3482961_0	1132509.C447_09085	4.164e-133	434.0	COG0451@1|root,arCOG03019@2157|Archaea,2XVZH@28890|Euryarchaeota,23U95@183963|Halobacteria	183963|Halobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_3485011_3	1289387.AUKW01000011_gene846	4.861e-30	122.0	arCOG06277@1|root,330C9@2|Bacteria,2IJX3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3485011_2	485913.Krac_6021	1.408e-50	203.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_3485011_0	1089545.KB913037_gene1342	1.889e-157	499.0	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria,4DZS4@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	cpo	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
SRR25158512_k127_3485011_1	42256.RradSPS_2536	4.07e-139	452.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_3486853_0	479434.Sthe_1841	1.633e-132	429.0	COG0346@1|root,COG0346@2|Bacteria,2G5Y9@200795|Chloroflexi,27XVR@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158512_k127_3486853_1	469383.Cwoe_4177	5.639e-71	259.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_3487154_0	266117.Rxyl_0016	1.857e-105	350.0	COG4221@1|root,COG4221@2|Bacteria,2I3DT@201174|Actinobacteria	201174|Actinobacteria	S	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_3487154_1	266117.Rxyl_1953	3.189e-48	178.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
SRR25158512_k127_3494778_2	1089551.KE386572_gene3214	3.538e-52	196.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TQZY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1175 ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158512_k127_3494778_1	66377.JOBH01000012_gene4310	8.346e-104	358.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria	201174|Actinobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158512_k127_3494778_0	525904.Tter_2056	9.987e-147	484.0	COG1063@1|root,COG1063@2|Bacteria,2NPFX@2323|unclassified Bacteria	2|Bacteria	E	Glucose dehydrogenase C-terminus	gutB_1	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_3506951_4	266117.Rxyl_2583	3.467e-09	63.0	COG2113@1|root,COG2113@2|Bacteria,2I2IV@201174|Actinobacteria	201174|Actinobacteria	E	glycine betaine	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158512_k127_3506951_2	1120972.AUMH01000011_gene133	3.366e-12	69.0	COG0582@1|root,COG0582@2|Bacteria,1W09X@1239|Firmicutes	1239|Firmicutes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158512_k127_3506951_1	103690.17131118	1.007e-12	73.0	2EFXV@1|root,339Q3@2|Bacteria,1GA81@1117|Cyanobacteria,1HT9V@1161|Nostocales	1117|Cyanobacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_3506951_0	365528.KB891126_gene3213	2.08e-112	369.0	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria,4ERM0@85013|Frankiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_3506951_3	1123296.JQKE01000032_gene1688	4.698e-10	64.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,2KPPX@206351|Neisseriales	206351|Neisseriales	Q	Type I secretion target GGXGXDXXX repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind,LysM
SRR25158512_k127_350820_11	987059.RBXJA2T_08930	1.191e-09	58.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,1KM43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158512_k127_350820_0	42256.RradSPS_2196	2.499e-215	678.0	COG0415@1|root,COG0415@2|Bacteria	2|Bacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158512_k127_350820_5	266117.Rxyl_2749	2.406e-88	297.0	COG1838@1|root,COG1838@2|Bacteria,2GK6D@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
SRR25158512_k127_350820_3	42256.RradSPS_2192	1.415e-138	469.0	COG1951@1|root,COG1951@2|Bacteria,2IGDQ@201174|Actinobacteria	201174|Actinobacteria	C	Tartrate dehydratase alpha subunit Fumarate hydratase class I N-terminal domain	ttdA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
SRR25158512_k127_350820_2	485913.Krac_2637	1.332e-141	459.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158512_k127_350820_7	485913.Krac_2637	8.746e-38	158.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158512_k127_350820_9	485913.Krac_2638	3.547e-31	125.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158512_k127_350820_8	485913.Krac_2639	9.432e-37	144.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158512_k127_350820_1	42256.RradSPS_0558	1.843e-177	562.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4CPWQ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158512_k127_3519117_2	42256.RradSPS_2657	8.509e-05	44.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158512_k127_3519117_0	485913.Krac_3042	3.372e-272	849.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
SRR25158512_k127_3527547_0	266117.Rxyl_0973	3.018e-162	517.0	COG0778@1|root,COG3576@1|root,COG0778@2|Bacteria,COG3576@2|Bacteria,2I2U7@201174|Actinobacteria,4CU67@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158512_k127_3527547_1	103690.17131118	1.482e-12	79.0	2EFXV@1|root,339Q3@2|Bacteria,1GA81@1117|Cyanobacteria,1HT9V@1161|Nostocales	1117|Cyanobacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_3527547_5	1172188.KB911822_gene702	1.13e-08	59.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,4FFCK@85021|Intrasporangiaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158512_k127_3527547_7	1166016.W5S_1125	2.471e-05	55.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,1MTZY@122277|Pectobacterium	1236|Gammaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	lapA	-	-	ko:K12549	-	-	-	-	ko00000	-	-	-	Big_3_2,Cadherin_3,Calx-beta,HemolysinCabind,VWA,VWA_2
SRR25158512_k127_3527547_4	652103.Rpdx1_2120	2.861e-10	71.0	2EB14@1|root,3351Z@2|Bacteria,1NG2T@1224|Proteobacteria,2UU2T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3527547_3	1173024.KI912149_gene6521	1.172e-10	68.0	2EFXV@1|root,339Q3@2|Bacteria,1GA81@1117|Cyanobacteria	1117|Cyanobacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_3527547_6	1122939.ATUD01000007_gene2023	1.117e-06	52.0	COG0662@1|root,COG0662@2|Bacteria,2GZ5U@201174|Actinobacteria,4CSXN@84995|Rubrobacteria	84995|Rubrobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_3527547_2	479434.Sthe_1552	5.285e-11	63.0	COG2197@1|root,COG2197@2|Bacteria,2G8M7@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_3538220_1	1131814.JAFO01000001_gene3317	1.497e-109	364.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,2TUS5@28211|Alphaproteobacteria,3F1WC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
SRR25158512_k127_3538220_0	266117.Rxyl_0702	7.419e-143	463.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CPG3@84995|Rubrobacteria	84995|Rubrobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158512_k127_3538220_2	266117.Rxyl_0701	1.646e-44	166.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	nfeD	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158512_k127_3538976_1	485913.Krac_6031	3.998e-77	269.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_3538976_0	485913.Krac_9650	2.889e-155	509.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158512_k127_3539019_1	266117.Rxyl_1131	1.245e-126	408.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
SRR25158512_k127_3539019_2	266117.Rxyl_1132	2.792e-113	371.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
SRR25158512_k127_3539019_4	214092.YPO2202	0.0005953	46.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,1S926@1236|Gammaproteobacteria,41G8R@629|Yersinia	1236|Gammaproteobacteria	S	bacterial OsmY and nodulation domain	osmY_1	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
SRR25158512_k127_3539019_3	266117.Rxyl_1133	2.397e-49	183.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
SRR25158512_k127_3539019_0	266117.Rxyl_1134	9.539e-180	567.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CPEU@84995|Rubrobacteria	84995|Rubrobacteria	G	alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158512_k127_3555483_0	266117.Rxyl_2535	0.0	1033.0	COG0567@1|root,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CPG1@84995|Rubrobacteria	84995|Rubrobacteria	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,Biotin_lipoyl,E1_dh,E3_binding,OxoGdeHyase_C,Transket_pyr
SRR25158512_k127_3555483_1	479434.Sthe_2057	2.724e-147	477.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,27XXQ@189775|Thermomicrobia	189775|Thermomicrobia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158512_k127_3555483_3	4155.Migut.K00158.1.p	0.0002819	51.0	COG0545@1|root,KOG0543@2759|Eukaryota,37PGW@33090|Viridiplantae,3GDE3@35493|Streptophyta,44DHI@71274|asterids	35493|Streptophyta	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005527,GO:0005528,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010286,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0033554,GO:0034605,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0061077,GO:0070370,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564	5.2.1.8	ko:K09571	ko04915,map04915	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	FKBP_C,TPR_1,TPR_2
SRR25158512_k127_3555483_2	649638.Trad_2819	6.734e-25	107.0	COG4113@1|root,COG4113@2|Bacteria,1WKRQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158512_k127_3556754_1	266117.Rxyl_2343	3.348e-62	218.0	COG1028@1|root,COG1028@2|Bacteria,2GJIH@201174|Actinobacteria,4CPS7@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158512_k127_3556754_0	266117.Rxyl_0355	4.134e-185	589.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4CQY0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD dependent oxidoreductase	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
SRR25158512_k127_3556754_2	266117.Rxyl_0358	1.609e-43	159.0	COG0044@1|root,COG0044@2|Bacteria,2GKEC@201174|Actinobacteria,4CRXW@84995|Rubrobacteria	84995|Rubrobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2,3.5.2.3	ko:K01464,ko:K01465	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046,M00051	R01993,R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158512_k127_3580014_2	266117.Rxyl_0679	5.387e-48	178.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4CQUG@84995|Rubrobacteria	84995|Rubrobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRR25158512_k127_3580014_0	1907.SGLAU_10050	2.242e-168	541.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158512_k127_3580014_1	266117.Rxyl_0232	8.299e-56	202.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2IE8G@201174|Actinobacteria,4CPJ4@84995|Rubrobacteria	84995|Rubrobacteria	I	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,SNARE_assoc
SRR25158512_k127_3580014_3	525904.Tter_1132	0.0001777	46.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158512_k127_358713_0	266117.Rxyl_2052	1.363e-254	807.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CPZQ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158512_k127_358713_1	266117.Rxyl_2051	2.266e-82	281.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	2|Bacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158512_k127_3606739_2	485913.Krac_3424	1.525e-43	160.0	COG3239@1|root,COG3239@2|Bacteria,2G80Y@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158512_k127_3606739_0	266117.Rxyl_2373	1.222e-84	293.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4CR8Q@84995|Rubrobacteria	84995|Rubrobacteria	S	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
SRR25158512_k127_3606739_4	266117.Rxyl_2967	3.049e-11	67.0	2FCRK@1|root,344US@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3606739_1	266117.Rxyl_2964	8.268e-46	170.0	COG1302@1|root,COG1302@2|Bacteria,2IMA3@201174|Actinobacteria,4CTN4@84995|Rubrobacteria	84995|Rubrobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158512_k127_3613707_0	266117.Rxyl_0358	3.346e-248	775.0	COG0044@1|root,COG0044@2|Bacteria,2GKEC@201174|Actinobacteria,4CRXW@84995|Rubrobacteria	84995|Rubrobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2,3.5.2.3	ko:K01464,ko:K01465	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046,M00051	R01993,R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158512_k127_3613707_1	266117.Rxyl_0365	1.155e-215	701.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158512_k127_3613707_2	1068980.ARVW01000001_gene118	4.571e-68	244.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4E3XV@85010|Pseudonocardiales	201174|Actinobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158512_k127_3619891_4	1122604.JONR01000018_gene1044	7.635e-12	68.0	2BISX@1|root,32D0N@2|Bacteria,1N7XS@1224|Proteobacteria,1SD95@1236|Gammaproteobacteria,1XBH6@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3619891_1	1038859.AXAU01000028_gene30	2.245e-98	340.0	COG0348@1|root,COG3889@1|root,COG0348@2|Bacteria,COG3889@2|Bacteria,1R9JQ@1224|Proteobacteria,2U3WR@28211|Alphaproteobacteria,3K36U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3619891_0	266117.Rxyl_2940	3.232e-199	630.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4CPKR@84995|Rubrobacteria	84995|Rubrobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158512_k127_3619891_2	266117.Rxyl_2939	3.09e-37	143.0	COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4CQD9@84995|Rubrobacteria	84995|Rubrobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SRR25158512_k127_3619891_3	266117.Rxyl_2938	6.785e-37	141.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CPAE@84995|Rubrobacteria	84995|Rubrobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158512_k127_3641899_1	266117.Rxyl_0342	2.586e-159	508.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4CPKY@84995|Rubrobacteria	84995|Rubrobacteria	E	NADH NADPH, small subunit	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158512_k127_3641899_0	525904.Tter_0474	0.0	1813.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158512_k127_3641899_3	1133850.SHJG_1792	3.746e-23	106.0	2EDR5@1|root,32UKZ@2|Bacteria,2ID1D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3642115_1	266117.Rxyl_0911	2.857e-108	361.0	COG0760@1|root,COG0760@2|Bacteria,2IGXV@201174|Actinobacteria,4CU3I@84995|Rubrobacteria	84995|Rubrobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	SurA_N_3
SRR25158512_k127_3642115_0	469383.Cwoe_5241	6.284e-242	783.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CP78@84995|Rubrobacteria	84995|Rubrobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158512_k127_3642115_4	266117.Rxyl_0908	2.284e-57	203.0	COG2050@1|root,COG2050@2|Bacteria,2IR9T@201174|Actinobacteria,4CTI0@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158512_k127_3642115_2	266117.Rxyl_0902	1.23e-84	290.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4CQ0Q@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_3642115_5	1183438.GKIL_3406	1.814e-38	149.0	COG0350@1|root,COG0350@2|Bacteria,1G0MX@1117|Cyanobacteria	1117|Cyanobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SRR25158512_k127_3642115_3	469383.Cwoe_1072	3.702e-77	264.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4CRKJ@84995|Rubrobacteria	84995|Rubrobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18
SRR25158512_k127_3643564_2	1297865.APJD01000003_gene6183	3.711e-14	76.0	2EKBW@1|root,33E29@2|Bacteria,1NEBH@1224|Proteobacteria,2UJN8@28211|Alphaproteobacteria,3K1Y5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3643564_1	266117.Rxyl_2006	3.64e-94	317.0	COG1481@1|root,COG1481@2|Bacteria	2|Bacteria	K	regulation of sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158512_k127_3643564_0	266117.Rxyl_2007	5.663e-146	469.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158512_k127_3644836_0	42256.RradSPS_1697	0.0	1163.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158512_k127_3644836_2	42256.RradSPS_1696	1.858e-38	149.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4CQM8@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158512_k127_3644836_3	266117.Rxyl_0131	1.318e-11	67.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07089,ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	ArsP_1,HMA
SRR25158512_k127_3644836_1	266117.Rxyl_2551	2.192e-122	396.0	COG5424@1|root,COG5424@2|Bacteria,2GYDT@201174|Actinobacteria	201174|Actinobacteria	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158512_k127_3650362_0	266117.Rxyl_2185	1.527e-206	647.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CPFJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158512_k127_3650362_2	266117.Rxyl_2186	5.828e-89	297.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158512_k127_3650362_1	266117.Rxyl_2187	1.797e-166	534.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CQ9P@84995|Rubrobacteria	84995|Rubrobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
SRR25158512_k127_3650362_4	525904.Tter_2628	4.11e-29	122.0	COG1302@1|root,COG1302@2|Bacteria,2NRH1@2323|unclassified Bacteria	2|Bacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158512_k127_3650362_3	266117.Rxyl_0458	7.104e-50	185.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4CQKG@84995|Rubrobacteria	84995|Rubrobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158512_k127_3650362_5	1463900.JOIX01000001_gene6610	7.201e-19	91.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
SRR25158512_k127_3653978_2	266117.Rxyl_1698	7.414e-212	662.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CRFS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.20	ko:K07749,ko:K18313	-	-	R10640,R10641	RC00014	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158512_k127_3653978_3	42256.RradSPS_1623	2.114e-93	312.0	COG1802@1|root,COG1802@2|Bacteria,2GMJX@201174|Actinobacteria,4CT3Z@84995|Rubrobacteria	84995|Rubrobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158512_k127_3653978_6	266117.Rxyl_0250	1.177e-57	209.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158512_k127_3653978_1	266117.Rxyl_1702	6.428e-279	872.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CPMC@84995|Rubrobacteria	84995|Rubrobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158512_k127_3653978_4	1128421.JAGA01000002_gene1141	8.278e-76	262.0	COG1024@1|root,COG1024@2|Bacteria,2NR3A@2323|unclassified Bacteria	2|Bacteria	I	Enoyl-CoA hydratase/isomerase	atuE	-	4.2.1.18,4.2.1.57	ko:K13766,ko:K13779	ko00280,ko00281,ko01100,map00280,map00281,map01100	M00036	R02085,R03493	RC00941,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158512_k127_3653978_0	266117.Rxyl_1703	1.554e-298	921.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CP83@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158512_k127_3653978_5	886293.Sinac_4135	2.669e-63	223.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_3659315_2	266117.Rxyl_2385	7.013e-74	249.0	COG3243@1|root,COG3243@2|Bacteria,2GP7I@201174|Actinobacteria,4CQCE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha beta hydrolase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Abhydrolase_1
SRR25158512_k127_3659315_1	42256.RradSPS_2801	2.793e-101	344.0	COG0477@1|root,COG2814@2|Bacteria,2GN6N@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4
SRR25158512_k127_3659315_5	1298880.AUEV01000015_gene33	5.255e-28	120.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158512_k127_3659315_4	1123024.AUII01000033_gene1403	1.121e-28	119.0	COG4994@1|root,COG4994@2|Bacteria,2ISVE@201174|Actinobacteria,4E603@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158512_k127_3659315_3	485913.Krac_0922	4.195e-32	129.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_3659315_0	479434.Sthe_3252	1.69e-115	381.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158512_k127_3659315_7	1122611.KB903940_gene1746	0.0001392	50.0	COG4585@1|root,COG4585@2|Bacteria,2GKRM@201174|Actinobacteria,4ENHV@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HisKA_3
SRR25158512_k127_366283_1	266117.Rxyl_2993	1.171e-91	305.0	COG1556@1|root,COG1556@2|Bacteria,2GY0B@201174|Actinobacteria	201174|Actinobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158512_k127_366283_0	266117.Rxyl_2994	3.073e-252	785.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4CPII@84995|Rubrobacteria	84995|Rubrobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158512_k127_366283_2	266117.Rxyl_2995	1.311e-44	163.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4CPUB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158512_k127_3664151_2	489825.LYNGBM3L_03790	3.368e-49	181.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
SRR25158512_k127_3664151_1	1121033.AUCF01000004_gene5038	7.711e-83	279.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,2JRYS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
SRR25158512_k127_3664151_4	1380394.JADL01000010_gene4101	4.698e-36	143.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2UFSH@28211|Alphaproteobacteria,2JUW5@204441|Rhodospirillales	204441|Rhodospirillales	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_3664151_3	1242864.D187_002003	1.164e-47	178.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,433GE@68525|delta/epsilon subdivisions,2WYHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Acetyltransferases including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158512_k127_3664151_0	1122223.KB890687_gene2687	8.634e-131	426.0	COG1167@1|root,COG1167@2|Bacteria,1WM9Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158512_k127_3670034_5	1336249.JADW01000017_gene596	2.375e-17	89.0	COG0006@1|root,COG0006@2|Bacteria,1RENF@1224|Proteobacteria,2U7VA@28211|Alphaproteobacteria,4BC69@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158512_k127_3670034_2	266117.Rxyl_2407	5.559e-114	376.0	COG1878@1|root,COG1878@2|Bacteria,2GUSA@201174|Actinobacteria,4CSW4@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158512_k127_3670034_3	42256.RradSPS_2498	5.274e-108	382.0	COG2197@1|root,COG2202@1|root,COG4585@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CT8E@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158512_k127_3670034_4	457570.Nther_2110	2.868e-35	156.0	COG2199@1|root,COG3437@1|root,COG4936@1|root,COG5002@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,COG4936@2|Bacteria,COG5002@2|Bacteria,1TQ0S@1239|Firmicutes	1239|Firmicutes	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,HisKA_7TM,PAS,PAS_3,PAS_4,PAS_9,PocR
SRR25158512_k127_3670034_1	365528.KB891126_gene3213	1.163e-116	381.0	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria,4ERM0@85013|Frankiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_3670034_0	266117.Rxyl_2399	1.132e-178	566.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CPIW@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158512_k127_3672965_1	42256.RradSPS_0281	5.157e-124	404.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158512_k127_3672965_0	42256.RradSPS_0282	3.495e-138	451.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4CQ7M@84995|Rubrobacteria	84995|Rubrobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_3672965_2	498761.HM1_1750	6.889e-71	257.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158512_k127_3676658_9	639030.JHVA01000001_gene2114	2.986e-38	155.0	COG2188@1|root,COG2188@2|Bacteria,3Y53X@57723|Acidobacteria,2JJQ1@204432|Acidobacteriia	204432|Acidobacteriia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158512_k127_3676658_0	42256.RradSPS_2629	3.529e-140	458.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CQA4@84995|Rubrobacteria	201174|Actinobacteria	C	COG COG1454 Alcohol dehydrogenase class IV Energy production and conversion	fucO	-	1.1.1.77,1.1.99.37,1.2.98.1	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	-	R00614,R01781,R02257	RC00034,RC00087,RC00099,RC00188	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158512_k127_3676658_3	318424.EU78_24910	1.088e-115	381.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,235SB@1762|Mycobacteriaceae	201174|Actinobacteria	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158512_k127_3676658_4	42256.RradSPS_2631	5.971e-112	380.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CPGF@84995|Rubrobacteria	84995|Rubrobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158512_k127_3676658_8	42256.RradSPS_2640	1.373e-55	207.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	ndx1	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
SRR25158512_k127_3676658_5	266117.Rxyl_0110	4.783e-106	349.0	COG2215@1|root,COG2215@2|Bacteria,2HRK4@201174|Actinobacteria,4CTM5@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3676658_6	926550.CLDAP_13630	2.873e-105	347.0	COG1830@1|root,COG1830@2|Bacteria,2G949@200795|Chloroflexi	200795|Chloroflexi	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SRR25158512_k127_3676658_2	266117.Rxyl_3110	1.74e-117	395.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4CS0X@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158512_k127_3676658_7	266117.Rxyl_0057	1.282e-104	349.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CRPW@84995|Rubrobacteria	84995|Rubrobacteria	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158512_k127_3676658_1	926550.CLDAP_13670	3.437e-138	449.0	COG1070@1|root,COG1070@2|Bacteria,2G7KS@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_3681426_4	1410665.JNKR01000007_gene667	0.0007563	44.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4H3ET@909932|Negativicutes	909932|Negativicutes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
SRR25158512_k127_3681426_3	266117.Rxyl_0088	1.12e-46	175.0	COG1510@1|root,COG1510@2|Bacteria,2GSV5@201174|Actinobacteria,4CTT2@84995|Rubrobacteria	84995|Rubrobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158512_k127_3681426_0	42256.RradSPS_2666	2.426e-141	457.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4CS0Z@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_3681426_2	42256.RradSPS_2665	1.126e-94	319.0	COG1277@1|root,COG1277@2|Bacteria,2ID14@201174|Actinobacteria,4CTMT@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158512_k127_3681426_1	266117.Rxyl_0091	2.575e-114	380.0	COG2607@1|root,COG2607@2|Bacteria,2H4JH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
SRR25158512_k127_3683560_1	266117.Rxyl_0170	2.385e-223	693.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158512_k127_3683560_0	266117.Rxyl_0168	2.621e-240	748.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158512_k127_3683560_3	266117.Rxyl_0167	7.587e-51	182.0	COG2146@1|root,COG2146@2|Bacteria,2HPIQ@201174|Actinobacteria,4CQW9@84995|Rubrobacteria	84995|Rubrobacteria	P	Rieske 2Fe-2S iron-sulphur domain	-	-	-	ko:K05710,ko:K14750	ko00360,ko00642,ko01100,ko01120,ko01220,map00360,map00642,map01100,map01120,map01220	M00545	R05440,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158512_k127_3683560_2	42256.RradSPS_2726	7.732e-81	271.0	COG3791@1|root,COG3791@2|Bacteria	2|Bacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158512_k127_3684194_0	266117.Rxyl_1227	2.506e-250	786.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CR8Y@84995|Rubrobacteria	84995|Rubrobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158512_k127_3684194_2	266117.Rxyl_1228	8.896e-69	235.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4CQQE@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158512_k127_3684194_3	42256.RradSPS_1102	6.949e-65	225.0	COG0454@1|root,COG0456@2|Bacteria,2IPBA@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_3684194_1	266117.Rxyl_1229	4.38e-96	320.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria	201174|Actinobacteria	S	Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158512_k127_3684194_4	42256.RradSPS_1217	3.873e-08	55.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158512_k127_370144_0	42256.RradSPS_1149	1.325e-92	314.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158512_k127_370144_3	350688.Clos_1000	9.091e-36	143.0	COG1670@1|root,COG1670@2|Bacteria,1V7SS@1239|Firmicutes,24JVH@186801|Clostridia,36JT6@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158512_k127_370144_2	266117.Rxyl_1148	1.263e-40	151.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158512_k127_370144_1	266117.Rxyl_1147	6.874e-63	220.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CP9J@84995|Rubrobacteria	84995|Rubrobacteria	L	AP endonuclease family 2	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158512_k127_3701799_2	1312954.KI914847_gene1620	8.665e-71	248.0	COG1233@1|root,COG1233@2|Bacteria,2I8A6@201174|Actinobacteria,1WAWR@1268|Micrococcaceae	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158512_k127_3701799_0	266117.Rxyl_2205	2.839e-132	426.0	COG0382@1|root,COG0382@2|Bacteria,2ICVY@201174|Actinobacteria	201174|Actinobacteria	H	UbiA prenyltransferase family	crtE	-	-	ko:K20616	-	-	-	-	ko00000	-	-	-	UbiA
SRR25158512_k127_3701799_1	1312954.KI914847_gene1613	2.771e-71	248.0	COG2324@1|root,COG2324@2|Bacteria	2|Bacteria	S	Carotenoid biosynthesis protein	cruF	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
SRR25158512_k127_3701799_4	1283299.AUKG01000004_gene950	8.687e-11	68.0	COG2165@1|root,COG2165@2|Bacteria,2GTN8@201174|Actinobacteria,4CQSF@84995|Rubrobacteria	84995|Rubrobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158512_k127_3721779_1	485913.Krac_4425	9.437e-114	383.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158512_k127_3721779_2	42256.RradSPS_1547	8.217e-93	308.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CPZA@84995|Rubrobacteria	84995|Rubrobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158512_k127_3721779_6	266117.Rxyl_0162	4.145e-21	95.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3,TPR_7,TPR_8
SRR25158512_k127_3721779_3	266117.Rxyl_2026	2.118e-65	233.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
SRR25158512_k127_3721779_0	42256.RradSPS_1733	1.777e-178	565.0	COG0371@1|root,COG0371@2|Bacteria,2GKWA@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158512_k127_3721779_8	42256.RradSPS_1213	0.0003445	50.0	COG0668@1|root,COG0668@2|Bacteria,2HRMR@201174|Actinobacteria,4CTPR@84995|Rubrobacteria	84995|Rubrobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
SRR25158512_k127_3727537_1	266117.Rxyl_1265	1.517e-75	258.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,2I4MX@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158512_k127_3727537_0	266117.Rxyl_1267	7.557e-199	624.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRR25158512_k127_3727537_3	266117.Rxyl_1269	4.46e-26	108.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CPY9@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158512_k127_3740525_2	1220582.RRU01S_23_00090	7.76e-64	226.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2U7KU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158512_k127_3740525_0	517433.PanABDRAFT_0482	1.879e-139	457.0	COG2271@1|root,COG2271@2|Bacteria,1QR12@1224|Proteobacteria,1SMAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_3740525_1	1126627.BAWE01000004_gene2372	6.201e-73	258.0	COG3386@1|root,COG3386@2|Bacteria,1R4XR@1224|Proteobacteria,2U1G5@28211|Alphaproteobacteria,3JXF8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SRR25158512_k127_3740525_3	1120950.KB892757_gene6417	1.129e-46	173.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4DPA7@85009|Propionibacteriales	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158512_k127_3745378_0	266117.Rxyl_1408	6.137e-133	432.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria	201174|Actinobacteria	D	Ribonuclease bn	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158512_k127_3745378_1	768671.ThimaDRAFT_1444	1.355e-55	205.0	2DBFU@1|root,2Z90B@2|Bacteria,1PI0M@1224|Proteobacteria,1RZW0@1236|Gammaproteobacteria,1X0BA@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
SRR25158512_k127_3750514_9	1337936.IJ00_01385	1.446e-11	66.0	COG1595@1|root,COG1595@2|Bacteria,1G6A9@1117|Cyanobacteria,1HU8U@1161|Nostocales	1117|Cyanobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_3750514_6	42256.RradSPS_2524	3.889e-47	179.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158512_k127_3750514_5	266117.Rxyl_1678	4.039e-88	295.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4CQN6@84995|Rubrobacteria	84995|Rubrobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158512_k127_3750514_0	42256.RradSPS_2471	1.736e-206	653.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_3750514_3	1278073.MYSTI_06040	9.313e-95	319.0	COG2227@1|root,COG2227@2|Bacteria,1QX77@1224|Proteobacteria,43C00@68525|delta/epsilon subdivisions,2X7AS@28221|Deltaproteobacteria,2YYR5@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158512_k127_3750514_1	986075.CathTA2_2770	6.802e-158	509.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli	91061|Bacilli	E	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158512_k127_3750514_4	266117.Rxyl_0774	9.468e-90	301.0	2C3PP@1|root,2Z954@2|Bacteria,2IB93@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_3750514_10	331869.BAL199_22942	4.792e-10	65.0	COG0702@1|root,COG0702@2|Bacteria,1RDKF@1224|Proteobacteria,2U7MU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158512_k127_3750514_7	485918.Cpin_3281	1.508e-25	111.0	COG0702@1|root,COG0702@2|Bacteria,4NMI5@976|Bacteroidetes,1ISKB@117747|Sphingobacteriia	976|Bacteroidetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158512_k127_3750514_2	266117.Rxyl_1058	2.135e-122	408.0	COG0477@1|root,COG0477@2|Bacteria,2I2QX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08168,ko:K18926	-	M00704,M00715	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3.16,2.A.1.3.22,2.A.1.3.30,2.A.1.3.6	-	-	MFS_1
SRR25158512_k127_3750514_8	1205910.B005_3530	1.578e-24	105.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EFHS@85012|Streptosporangiales	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158512_k127_3754668_2	266117.Rxyl_0770	1.573e-35	138.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158512_k127_3754668_1	42256.RradSPS_0636	1.15e-205	644.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CQA4@84995|Rubrobacteria	201174|Actinobacteria	C	COG COG1454 Alcohol dehydrogenase class IV Energy production and conversion	-	-	1.1.1.1,1.1.1.202	ko:K00086,ko:K11440	ko00260,ko00561,ko00640,ko01100,map00260,map00561,map00640,map01100	M00555	R02377,R03119,R08557,R08558	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
SRR25158512_k127_3754668_0	42256.RradSPS_0635	2.059e-240	752.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CQYS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158512_k127_3754668_3	1051985.l11_17970	6.818e-13	69.0	COG2189@1|root,COG2189@2|Bacteria,1R0UJ@1224|Proteobacteria,2WHX6@28216|Betaproteobacteria,2KTF7@206351|Neisseriales	206351|Neisseriales	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR25158512_k127_3768382_0	42256.RradSPS_1839	0.0	1165.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2IBPW@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158512_k127_3768382_3	266117.Rxyl_2059	1.462e-48	178.0	COG1695@1|root,COG1695@2|Bacteria,2HP67@201174|Actinobacteria,4CQHX@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_3768382_1	1312959.KI914622_gene2258	4.289e-183	580.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,1W7H7@1268|Micrococcaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_3768382_2	42256.RradSPS_1847	1.261e-145	468.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4CQBQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_3779964_0	266117.Rxyl_1519	8.181e-126	412.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4CPP2@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158512_k127_3779964_5	42256.RradSPS_1527	7.114e-35	138.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4CQW7@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158512_k127_3779964_3	1449347.JQLN01000005_gene5197	9.224e-55	201.0	29SM0@1|root,30DSB@2|Bacteria,2GN13@201174|Actinobacteria,2M16J@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158512_k127_3779964_4	42256.RradSPS_1528	1.359e-51	186.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CQDN@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158512_k127_3779964_1	266117.Rxyl_1522	3.255e-103	339.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CQ75@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158512_k127_3779964_2	42256.RradSPS_1530	7.115e-69	237.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CPMW@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158512_k127_3786564_4	42256.RradSPS_1248	2.523e-31	127.0	COG0168@1|root,COG0168@2|Bacteria,2HNZI@201174|Actinobacteria,4CQ92@84995|Rubrobacteria	84995|Rubrobacteria	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158512_k127_3786564_2	42256.RradSPS_1253	2.251e-95	317.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria,4CQAW@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
SRR25158512_k127_3786564_3	266117.Rxyl_1282	3.138e-60	211.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158512_k127_3786564_0	266117.Rxyl_1283	6.166e-275	855.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158512_k127_3786564_1	266117.Rxyl_1287	1.982e-200	630.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2GJUZ@201174|Actinobacteria,4CPSM@84995|Rubrobacteria	84995|Rubrobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158512_k127_3804454_3	42256.RradSPS_2494	1.646e-14	75.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_3804454_0	42256.RradSPS_2491	8.819e-110	360.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
SRR25158512_k127_3804454_2	1041930.Mtc_1483	2.986e-36	143.0	COG0589@1|root,arCOG02053@2157|Archaea,2XZV8@28890|Euryarchaeota	28890|Euryarchaeota	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_3804454_1	266117.Rxyl_3070	6.914e-67	236.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_3809320_0	266117.Rxyl_2856	7.306e-253	786.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CPJH@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158512_k127_381986_0	42256.RradSPS_2692	1.899e-160	509.0	COG1222@1|root,COG1222@2|Bacteria,2GJNW@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA
SRR25158512_k127_381986_2	1096546.WYO_3417	0.0009133	46.0	COG0596@1|root,COG0596@2|Bacteria,1R4N4@1224|Proteobacteria,2TYMB@28211|Alphaproteobacteria,1JWZR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158512_k127_381986_1	1348663.KCH_28900	5.586e-39	154.0	29SM0@1|root,30DSB@2|Bacteria,2GN13@201174|Actinobacteria,2M16J@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158512_k127_3830374_1	266117.Rxyl_1441	2.127e-121	398.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CPPD@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158512_k127_3830374_3	266117.Rxyl_1440	1.714e-81	285.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CQCH@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158512_k127_3830374_6	42256.RradSPS_1445	5.379e-57	206.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,4CU30@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158512_k127_3830374_0	266117.Rxyl_1438	4.357e-205	648.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CPBT@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158512_k127_3830374_5	266117.Rxyl_1434	2.251e-64	224.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4CQ8I@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158512_k127_3830374_2	42256.RradSPS_1440	1.601e-107	355.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CPZY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158512_k127_3830374_4	42256.RradSPS_1439	2.002e-70	243.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CQ53@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158512_k127_3832087_0	525904.Tter_1501	0.0	1035.0	COG0383@1|root,COG0383@2|Bacteria,2NNPD@2323|unclassified Bacteria	2|Bacteria	G	Glycoside hydrolase family 38 central region	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158512_k127_3832425_1	266117.Rxyl_0933	5.361e-160	509.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria	84995|Rubrobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158512_k127_3832425_0	266117.Rxyl_2674	2.763e-192	606.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CTDV@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158512_k127_3832425_3	42256.RradSPS_0018	1.656e-46	172.0	COG1714@1|root,COG1714@2|Bacteria,2HP4S@201174|Actinobacteria,4CQGE@84995|Rubrobacteria	84995|Rubrobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158512_k127_3832425_2	745776.DGo_CA2326	2.706e-86	297.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	dMI1	-	3.1.4.46	ko:K01126,ko:K10716	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Castor_Poll_mid,TrkA_N
SRR25158512_k127_3847433_1	266117.Rxyl_0698	3.445e-38	149.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria,4CQE8@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158512_k127_3847433_0	42256.RradSPS_0358	4.992e-193	635.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158512_k127_3855147_4	161528.ED21_22019	6.228e-08	54.0	29CWT@1|root,2ZZUX@2|Bacteria,1REF2@1224|Proteobacteria,2U7K7@28211|Alphaproteobacteria,2K4SS@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2585)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2585
SRR25158512_k127_3855147_2	639030.JHVA01000001_gene2630	5.455e-32	130.0	COG5552@1|root,COG5552@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158512_k127_3855147_1	411476.BACOVA_01092	2.436e-33	134.0	2BY2M@1|root,3422H@2|Bacteria,4P4QU@976|Bacteroidetes,2FTGG@200643|Bacteroidia,4ASFG@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
SRR25158512_k127_3855147_0	2002.JOEQ01000004_gene2975	1.486e-49	193.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EHIY@85012|Streptosporangiales	201174|Actinobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_3855147_3	525909.Afer_0695	1.315e-12	69.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4CNCN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_3857420_0	42256.RradSPS_0254	1.289e-202	642.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,4CQ82@84995|Rubrobacteria	84995|Rubrobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158512_k127_3857420_1	266117.Rxyl_2983	9.624e-133	424.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CU2Q@84995|Rubrobacteria	84995|Rubrobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_3857420_2	266117.Rxyl_2982	2.246e-103	346.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158512_k127_385782_2	266117.Rxyl_3071	3.123e-50	183.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_385782_1	42256.RradSPS_2497	3.702e-64	229.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	ahyR	-	-	ko:K07782,ko:K15852	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Autoind_bind,GerE
SRR25158512_k127_385782_0	266117.Rxyl_3085	5.869e-83	284.0	COG0589@1|root,COG0589@2|Bacteria,2HR8H@201174|Actinobacteria,4CT4U@84995|Rubrobacteria	84995|Rubrobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_385782_3	313624.NSP_48390	3.349e-06	51.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HKMC@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4
SRR25158512_k127_3862779_3	42256.RradSPS_1217	1.648e-27	119.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158512_k127_3862779_0	266117.Rxyl_1231	1.097e-148	475.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158512_k127_3862779_1	266117.Rxyl_1232	8.14e-109	360.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
SRR25158512_k127_3862779_2	266117.Rxyl_1233	6.946e-37	141.0	COG2329@1|root,COG2329@2|Bacteria,2HRPP@201174|Actinobacteria,4CTS2@84995|Rubrobacteria	84995|Rubrobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	1.14.99.48	ko:K07145	ko00860,ko01110,map00860,map01110	-	R10468,R10510	RC03185	ko00000,ko00001,ko01000	-	-	-	ABM
SRR25158512_k127_387577_6	266117.Rxyl_2421	4.889e-51	187.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158512_k127_387577_3	266117.Rxyl_2422	4.05e-137	441.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CSSZ@84995|Rubrobacteria	84995|Rubrobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158512_k127_387577_4	266117.Rxyl_2423	9.149e-136	439.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CSUV@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158512_k127_387577_1	266117.Rxyl_2424	8.375e-239	751.0	COG0747@1|root,COG0747@2|Bacteria,2HEVF@201174|Actinobacteria,4CSTE@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158512_k127_387577_5	266117.Rxyl_2425	2.798e-100	331.0	COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158512_k127_387577_2	42256.RradSPS_0549	1.579e-192	617.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria	201174|Actinobacteria	M	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158512_k127_387577_0	266117.Rxyl_2428	0.0	1480.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158512_k127_3880202_1	266117.Rxyl_1503	7.165e-134	434.0	COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CPM8@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
SRR25158512_k127_3880202_6	1206737.BAGF01000027_gene1446	1.806e-29	127.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4FXP4@85025|Nocardiaceae	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158512_k127_3880202_2	42256.RradSPS_1512	3.186e-112	366.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4CQRI@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158512_k127_3880202_0	266117.Rxyl_1506	5.29e-148	474.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CPY3@84995|Rubrobacteria	84995|Rubrobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158512_k127_3880202_4	266117.Rxyl_1507	1.298e-45	179.0	COG0295@1|root,COG0295@2|Bacteria,2IHP7@201174|Actinobacteria	201174|Actinobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	CYTH,dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158512_k127_3880202_3	266117.Rxyl_1508	5.403e-93	311.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,2H9K9@201174|Actinobacteria	201174|Actinobacteria	M	Prokaryotic diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
SRR25158512_k127_3880202_5	266117.Rxyl_1509	1.008e-44	166.0	COG0319@1|root,COG0319@2|Bacteria,2HN3K@201174|Actinobacteria,4CQHV@84995|Rubrobacteria	84995|Rubrobacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158512_k127_3880202_7	42256.RradSPS_1517	2.68e-24	103.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158512_k127_3890543_2	266117.Rxyl_0136	1.364e-87	293.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4CQ4C@84995|Rubrobacteria	84995|Rubrobacteria	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158512_k127_3890543_1	266117.Rxyl_0135	6.947e-104	344.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158512_k127_3890543_0	42256.RradSPS_2595	5.501e-131	424.0	COG1409@1|root,COG1409@2|Bacteria,2GU3Z@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158512_k127_3902674_0	266117.Rxyl_0682	1.799e-140	453.0	COG3540@1|root,COG3540@2|Bacteria,2GNZ5@201174|Actinobacteria,4CRFP@84995|Rubrobacteria	84995|Rubrobacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158512_k127_3902674_5	1122921.KB898189_gene456	2.92e-07	59.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,4I26M@91061|Bacilli,2705Y@186822|Paenibacillaceae	91061|Bacilli	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_3902674_3	42256.RradSPS_2498	3.631e-17	88.0	COG2197@1|root,COG2202@1|root,COG4585@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CT8E@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158512_k127_3902674_2	631454.N177_1901	3.467e-18	88.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR25158512_k127_3902674_4	67332.FM21_17305	1.01e-07	61.0	COG3293@1|root,COG3293@2|Bacteria,2GMT0@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR25158512_k127_3902674_1	420324.KI912045_gene4200	4.017e-40	153.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,1JTPR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
SRR25158512_k127_3903585_0	266117.Rxyl_1310	5.993e-259	812.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158512_k127_3903585_1	266117.Rxyl_1311	4.158e-188	594.0	COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CPR4@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158512_k127_3906924_0	485913.Krac_6991	4.084e-153	509.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158512_k127_3906924_2	485913.Krac_6031	4.714e-82	280.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_3906924_5	266117.Rxyl_2075	7.955e-54	196.0	COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CQF3@84995|Rubrobacteria	84995|Rubrobacteria	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158512_k127_3906924_1	266117.Rxyl_2074	1.515e-126	412.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4CQEA@84995|Rubrobacteria	84995|Rubrobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
SRR25158512_k127_3906924_4	1449355.JQNR01000005_gene5026	6.989e-63	225.0	COG0500@1|root,COG0500@2|Bacteria,2I3FS@201174|Actinobacteria	201174|Actinobacteria	Q	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158512_k127_3906924_6	649638.Trad_0093	1.125e-17	89.0	COG3918@1|root,COG3918@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRR25158512_k127_3906924_3	266117.Rxyl_2072	1.301e-74	252.0	COG0473@1|root,COG0473@2|Bacteria,2I4BP@201174|Actinobacteria,4CPAZ@84995|Rubrobacteria	84995|Rubrobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
SRR25158512_k127_3908833_5	42256.RradSPS_1911	1.048e-60	211.0	COG0619@1|root,COG0619@2|Bacteria,2INV1@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16783,ko:K16785	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158512_k127_3908833_1	266117.Rxyl_2123	1.268e-88	301.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CQ1A@84995|Rubrobacteria	84995|Rubrobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158512_k127_3908833_2	266117.Rxyl_2122	5.072e-77	263.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4CQMJ@84995|Rubrobacteria	84995|Rubrobacteria	S	O-methyltransferase family 3	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRR25158512_k127_3908833_7	118161.KB235923_gene6583	2.341e-43	164.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	hit-1	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158512_k127_3908833_3	266117.Rxyl_2121	1.781e-66	229.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CQAX@84995|Rubrobacteria	84995|Rubrobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158512_k127_3908833_4	266117.Rxyl_2120	5.742e-62	214.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CQGC@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158512_k127_3908833_0	42256.RradSPS_1906	1.21e-190	607.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CP8E@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158512_k127_3908833_6	266117.Rxyl_2118	4.664e-56	202.0	COG4328@1|root,COG4328@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,RelA_SpoT
SRR25158512_k127_391906_1	266117.Rxyl_2678	4.222e-91	307.0	COG4122@1|root,COG4122@2|Bacteria,2IR7F@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158512_k127_391906_2	479434.Sthe_2580	7.799e-63	223.0	COG0702@1|root,COG0702@2|Bacteria,2G78J@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR25158512_k127_3921106_0	266117.Rxyl_2529	4.123e-258	809.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158512_k127_3921106_1	1122138.AQUZ01000006_gene1315	5.418e-127	419.0	COG1572@1|root,COG3227@1|root,COG1572@2|Bacteria,COG3227@2|Bacteria,2IDQA@201174|Actinobacteria,4DP0D@85009|Propionibacteriales	201174|Actinobacteria	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
SRR25158512_k127_3932474_0	266117.Rxyl_2376	8.594e-194	614.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4CQPE@84995|Rubrobacteria	84995|Rubrobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
SRR25158512_k127_3932474_1	525904.Tter_2119	1.531e-105	348.0	COG1028@1|root,COG1028@2|Bacteria,2NRAR@2323|unclassified Bacteria	525904.Tter_2119|-	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	-
SRR25158512_k127_3985239_1	471857.Svir_06850	6.697e-08	63.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,4E186@85010|Pseudonocardiales	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158512_k127_3985239_0	42256.RradSPS_1613	5.831e-175	560.0	COG3408@1|root,COG3408@2|Bacteria,2I3UW@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100,Glyco_hydro_63,Trehalase
SRR25158512_k127_3994457_1	1120959.ATXF01000005_gene995	1.07e-80	280.0	COG1808@1|root,COG1808@2|Bacteria,2HT7X@201174|Actinobacteria,4FSDX@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158512_k127_3994457_3	443218.AS9A_4259	8.035e-14	75.0	2EFXV@1|root,339Q3@2|Bacteria	2|Bacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_3994457_2	1394178.AWOO02000001_gene1396	3.576e-42	158.0	COG3795@1|root,COG3795@2|Bacteria,2IQMR@201174|Actinobacteria,4EQ6M@85012|Streptosporangiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158512_k127_3994457_0	1463879.JOHP01000015_gene4597	7.135e-137	445.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_3997512_0	266117.Rxyl_0098	1.569e-204	642.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CPEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158512_k127_3997512_1	509190.Cseg_2686	3.444e-86	294.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,2KF17@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158512_k127_3997512_2	266117.Rxyl_0096	3.597e-58	206.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CQJH@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158512_k127_3999187_2	42256.RradSPS_2813	1.161e-44	162.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4CR3N@84995|Rubrobacteria	84995|Rubrobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_3999187_1	1386089.N865_09660	5.808e-96	329.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
SRR25158512_k127_3999187_0	405948.SACE_7076	4.705e-146	480.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4E11F@85010|Pseudonocardiales	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158512_k127_4004903_2	266117.Rxyl_3069	7.446e-78	265.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	1.8.5.2	ko:K15977,ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158512_k127_4004903_4	266117.Rxyl_0906	2.838e-39	149.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,4CQQK@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158512_k127_4004903_3	266117.Rxyl_0907	4.183e-50	182.0	COG2259@1|root,COG2259@2|Bacteria,2HP7E@201174|Actinobacteria,4CQJN@84995|Rubrobacteria	84995|Rubrobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158512_k127_4004903_5	1122925.KB895378_gene2466	2.249e-07	60.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,4I26M@91061|Bacilli,2705Y@186822|Paenibacillaceae	91061|Bacilli	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4004903_1	1056816.JAFQ01000004_gene794	4.221e-157	503.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4FY54@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_4004903_0	1056816.JAFQ01000004_gene795	1.117e-158	503.0	COG1396@1|root,COG1396@2|Bacteria,2GKRR@201174|Actinobacteria,4FZEW@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158512_k127_4008361_0	266117.Rxyl_1983	1.974e-179	576.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria,4CPAR@84995|Rubrobacteria	84995|Rubrobacteria	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158512_k127_4008361_1	266117.Rxyl_1986	8.568e-160	515.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CT3X@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158512_k127_4008361_6	266117.Rxyl_1987	5.184e-19	88.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158512_k127_4008361_2	266117.Rxyl_1988	2.048e-137	443.0	COG3481@1|root,COG3481@2|Bacteria,2IRFS@201174|Actinobacteria,4CPMU@84995|Rubrobacteria	84995|Rubrobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD
SRR25158512_k127_4008361_3	42256.RradSPS_1767	2.258e-120	391.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4CPZI@84995|Rubrobacteria	84995|Rubrobacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158512_k127_4015638_2	886293.Sinac_3591	4.414e-53	191.0	COG3153@1|root,COG3153@2|Bacteria,2IZPX@203682|Planctomycetes	203682|Planctomycetes	S	Acetyltransferase (GNAT) family	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
SRR25158512_k127_4015638_0	266117.Rxyl_2927	1.436e-109	364.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CQZ4@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158512_k127_4015638_3	266117.Rxyl_2928	8.161e-48	174.0	COG0640@1|root,COG0640@2|Bacteria,2IJHT@201174|Actinobacteria,4CTWE@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158512_k127_4015638_1	1173027.Mic7113_3214	3.767e-78	268.0	COG1011@1|root,COG1011@2|Bacteria,1G4JI@1117|Cyanobacteria,1H8VT@1150|Oscillatoriales	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158512_k127_4015638_4	1125973.JNLC01000014_gene2478	2.006e-47	180.0	COG0500@1|root,COG2226@2|Bacteria,1N5QH@1224|Proteobacteria,2UM5M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SRR25158512_k127_4016903_1	42256.RradSPS_0395	3.07e-174	553.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CPRJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158512_k127_4016903_2	266117.Rxyl_2550	3.175e-129	417.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CPMX@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158512_k127_4016903_3	211165.AJLN01000047_gene6155	8.939e-88	295.0	COG4976@1|root,COG4976@2|Bacteria,1G290@1117|Cyanobacteria,1JJRS@1189|Stigonemataceae	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158512_k127_4016903_4	266117.Rxyl_2551	4.356e-10	64.0	COG5424@1|root,COG5424@2|Bacteria,2GYDT@201174|Actinobacteria	201174|Actinobacteria	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158512_k127_4016903_0	42256.RradSPS_2597	4.726e-316	980.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158512_k127_4019248_0	266117.Rxyl_1539	5.92e-272	852.0	COG1226@1|root,COG3273@1|root,COG4651@1|root,COG1226@2|Bacteria,COG3273@2|Bacteria,COG4651@2|Bacteria,2I4BK@201174|Actinobacteria,4CQQT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR25158512_k127_4019248_1	1122182.KB903837_gene3800	8.336e-80	281.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4DM5Z@85008|Micromonosporales	201174|Actinobacteria	I	Carboxylesterase family	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
SRR25158512_k127_4026954_2	266117.Rxyl_1687	9.894e-52	187.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4CPZR@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM regulatory protein DeoR	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
SRR25158512_k127_4026954_1	1068978.AMETH_6744	2.498e-153	496.0	COG0477@1|root,COG0477@2|Bacteria,2GNCX@201174|Actinobacteria,4DY06@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K06610	-	-	-	-	ko00000,ko02000	2.A.1.1.27	-	-	MFS_1,Sugar_tr
SRR25158512_k127_4026954_0	1394178.AWOO02000036_gene8934	3.194e-209	668.0	COG3408@1|root,COG3408@2|Bacteria,2H2QX@201174|Actinobacteria,4EMPK@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
SRR25158512_k127_4031615_1	42256.RradSPS_2114	8.457e-110	373.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158512_k127_4031615_2	926560.KE387025_gene4131	1.113e-90	307.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_4031615_4	1382356.JQMP01000003_gene1363	1.492e-52	197.0	COG0491@1|root,COG0491@2|Bacteria,2GBAB@200795|Chloroflexi,27YH3@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158512_k127_4031615_6	330214.NIDE2963	8.583e-27	115.0	COG1846@1|root,COG1846@2|Bacteria,3J13N@40117|Nitrospirae	40117|Nitrospirae	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158512_k127_4031615_3	926569.ANT_10500	4.743e-87	297.0	COG0524@1|root,COG0524@2|Bacteria,2G73H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	2.7.1.15,2.7.1.4	ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158512_k127_4031615_0	63737.Npun_F4709	5.375e-161	537.0	COG0297@1|root,COG0297@2|Bacteria,1G3UW@1117|Cyanobacteria,1HQ2G@1161|Nostocales	1117|Cyanobacteria	G	Sucrose synthase	-	-	2.4.1.14	ko:K00696	ko00500,ko01100,map00500,map01100	-	R00766	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_trans_4_4,Glycos_transf_1
SRR25158512_k127_4031615_5	1185876.BN8_04506	8.638e-51	206.0	COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,47JV1@768503|Cytophagia	976|Bacteroidetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.4,2.7.1.92	ko:K00847,ko:K03338	ko00051,ko00500,ko00520,ko00562,ko01100,ko01120,map00051,map00500,map00520,map00562,map01100,map01120	-	R00760,R00867,R03920,R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158512_k127_4040332_0	42256.RradSPS_2712	1.164e-166	533.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4CQ6J@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase family M20/M25/M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158512_k127_4040332_1	266117.Rxyl_2188	2.514e-98	338.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria,4CTB9@84995|Rubrobacteria	84995|Rubrobacteria	M	COG COG1404 Subtilisin-like serine proteases Posttranslational modification protein turnover chaperones	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158512_k127_4040332_2	42256.RradSPS_0537	1.254e-56	200.0	COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,4CP7F@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158512_k127_404139_2	266117.Rxyl_2411	4.594e-34	136.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158512_k127_404139_0	266117.Rxyl_2410	0.0	1021.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158512_k127_404139_1	1194972.MVAC_00965	3.161e-101	336.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,233BF@1762|Mycobacteriaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158512_k127_4041543_2	266117.Rxyl_2368	2.643e-41	154.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4CS43@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158512_k127_4041543_1	42256.RradSPS_2058	2.65e-44	168.0	COG0824@1|root,COG0824@2|Bacteria,2IINH@201174|Actinobacteria,4CQTD@84995|Rubrobacteria	84995|Rubrobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158512_k127_4041543_3	351607.Acel_0245	1.383e-31	134.0	2EBHZ@1|root,335IE@2|Bacteria,2GNMR@201174|Actinobacteria,4EV8Z@85013|Frankiales	201174|Actinobacteria	S	Phosphatase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	-	-	-	-	-	-	-	-	-	-	Phosphatase
SRR25158512_k127_4041543_0	927677.ALVU02000004_gene4738	5.451e-64	236.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,DUF4062,NB-ARC,TPR_12
SRR25158512_k127_4047352_0	42256.RradSPS_2228	9.767e-315	975.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CPJQ@84995|Rubrobacteria	84995|Rubrobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158512_k127_4047352_1	266117.Rxyl_1241	1.016e-116	394.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
SRR25158512_k127_4047352_4	42256.RradSPS_2238	7.66e-47	176.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158512_k127_4047352_2	28042.GU90_02065	3.721e-83	279.0	COG1972@1|root,COG1972@2|Bacteria,2IB7W@201174|Actinobacteria	201174|Actinobacteria	F	Nucleoside transporter	yutK	-	-	ko:K03317,ko:K11535,ko:K16323	-	-	-	-	ko00000,ko02000	2.A.41,2.A.41.1	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
SRR25158512_k127_4048489_11	1120950.KB892727_gene1941	2.629e-48	177.0	COG2072@1|root,COG2072@2|Bacteria,2GJWE@201174|Actinobacteria,4DRR6@85009|Propionibacteriales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	K_oxygenase,Pyr_redox_2,Pyr_redox_3
SRR25158512_k127_4048489_10	266117.Rxyl_0659	1.86e-60	226.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4CQQD@84995|Rubrobacteria	84995|Rubrobacteria	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158512_k127_4048489_6	266117.Rxyl_0658	3.882e-161	522.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CSM9@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158512_k127_4048489_13	1146883.BLASA_3996	8.239e-22	104.0	COG1917@1|root,COG1917@2|Bacteria,2I3J0@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_4048489_7	266117.Rxyl_0655	3.923e-133	429.0	COG0428@1|root,COG0428@2|Bacteria,2HEM8@201174|Actinobacteria	201174|Actinobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158512_k127_4048489_3	1405.DJ92_4429	1.493e-172	551.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,1ZCHH@1386|Bacillus	91061|Bacilli	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	iYO844.BSU04360	Nramp
SRR25158512_k127_4048489_2	266117.Rxyl_0084	2.364e-180	571.0	COG0428@1|root,COG0428@2|Bacteria,2ICIQ@201174|Actinobacteria,4CSVK@84995|Rubrobacteria	84995|Rubrobacteria	P	Mediates zinc uptake. May also transport other divalent cations	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4048489_5	266117.Rxyl_0083	1.122e-164	531.0	COG2132@1|root,COG2132@2|Bacteria,2HPY5@201174|Actinobacteria,4CRDC@84995|Rubrobacteria	84995|Rubrobacteria	Q	PFAM multicopper oxidase type	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158512_k127_4048489_14	42256.RradSPS_1206	4.313e-14	85.0	COG2132@1|root,COG3485@1|root,COG2132@2|Bacteria,COG3485@2|Bacteria,2IDP7@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3
SRR25158512_k127_4048489_9	42256.RradSPS_2226	1.476e-86	291.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158512_k127_4048489_8	1173022.Cri9333_0829	1.045e-129	421.0	COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,1H88F@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158512_k127_4048489_4	485913.Krac_10865	7.163e-165	528.0	COG2425@1|root,COG2425@2|Bacteria	2|Bacteria	S	positive regulation of ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
SRR25158512_k127_4048489_0	485913.Krac_10864	8.112e-239	758.0	COG1916@1|root,COG1916@2|Bacteria,2G7ZE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4048489_1	1382306.JNIM01000001_gene1693	1.748e-181	573.0	COG0714@1|root,COG0714@2|Bacteria,2G82X@200795|Chloroflexi	200795|Chloroflexi	L	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158512_k127_4048489_12	1246995.AFR_32205	2.8e-36	152.0	COG4715@1|root,COG5094@1|root,COG4715@2|Bacteria,COG5094@2|Bacteria,2GKC8@201174|Actinobacteria,4D9VB@85008|Micromonosporales	201174|Actinobacteria	K	PFAM zinc finger SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
SRR25158512_k127_4051930_6	1123023.JIAI01000011_gene8918	3.123e-16	88.0	COG1971@1|root,COG1971@2|Bacteria,2IFUP@201174|Actinobacteria,4EAUX@85010|Pseudonocardiales	201174|Actinobacteria	P	Putative manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
SRR25158512_k127_4051930_1	526225.Gobs_2456	6.447e-180	572.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158512_k127_4051930_5	2074.JNYD01000005_gene3075	5.535e-20	100.0	2E4CK@1|root,339II@2|Bacteria,2GSHC@201174|Actinobacteria,4E7C1@85010|Pseudonocardiales	201174|Actinobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	ko:K06138	-	-	-	-	ko00000	-	-	-	PqqD
SRR25158512_k127_4051930_3	526225.Gobs_2454	2.903e-113	371.0	COG5424@1|root,COG5424@2|Bacteria,2I9SS@201174|Actinobacteria	201174|Actinobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
SRR25158512_k127_4051930_2	2074.JNYD01000005_gene3073	2.318e-135	436.0	COG1235@1|root,COG1235@2|Bacteria,2HBMA@201174|Actinobacteria,4DZUU@85010|Pseudonocardiales	201174|Actinobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
SRR25158512_k127_4051930_0	526225.Gobs_2451	3.814e-311	959.0	COG4993@1|root,COG4993@2|Bacteria,2I3R4@201174|Actinobacteria	201174|Actinobacteria	G	PQQ enzyme repeat	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
SRR25158512_k127_4051930_4	526225.Gobs_2450	6.211e-68	238.0	COG3794@1|root,COG3794@2|Bacteria,2IGTP@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4054114_6	266117.Rxyl_1248	1.492e-72	251.0	COG0406@1|root,COG0406@2|Bacteria,2HGEQ@201174|Actinobacteria,4CSEQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158512_k127_4054114_4	266117.Rxyl_1247	1.338e-91	306.0	COG1278@1|root,COG1278@2|Bacteria,2HR26@201174|Actinobacteria,4CSWY@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SRR25158512_k127_4054114_7	42256.RradSPS_1224	2.886e-29	118.0	COG1715@1|root,COG1715@2|Bacteria	2|Bacteria	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	HARE-HTH,Mrr_cat
SRR25158512_k127_4054114_0	266117.Rxyl_1244	4.474e-175	557.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,2GJQ5@201174|Actinobacteria,4CQFQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158512_k127_4054114_1	266117.Rxyl_1243	9.99e-115	375.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria	84995|Rubrobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158512_k127_4054114_2	266117.Rxyl_1234	1.132e-113	370.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	ntcA	GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009416,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019216,GO:0019219,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043565,GO:0045828,GO:0045834,GO:0045893,GO:0045935,GO:0046889,GO:0046890,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071214,GO:0071478,GO:0071482,GO:0080090,GO:0097159,GO:0104004,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1904143,GO:2000112,GO:2001141	-	ko:K01420,ko:K10914,ko:K21561,ko:K22490	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158512_k127_4066588_1	357808.RoseRS_2528	1.201e-150	487.0	COG0665@1|root,COG0665@2|Bacteria,2G80C@200795|Chloroflexi,376QJ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158512_k127_4066588_0	266117.Rxyl_2925	1.393e-277	859.0	COG1012@1|root,COG1012@2|Bacteria,2GT45@201174|Actinobacteria,4CPPU@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158512_k127_4066588_2	42256.RradSPS_0320	5.21e-41	162.0	COG0506@1|root,COG0506@2|Bacteria,2GJTK@201174|Actinobacteria,4CQPH@84995|Rubrobacteria	84995|Rubrobacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158512_k127_4080365_3	266117.Rxyl_1482	2.03e-40	151.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158512_k127_4080365_1	1464048.JNZS01000012_gene3501	1.263e-110	363.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria,4DB65@85008|Micromonosporales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158512_k127_4080365_0	105422.BBPM01000009_gene6774	4.172e-139	451.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,2NEGH@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158512_k127_4080365_2	378806.STAUR_5280	1.081e-78	276.0	COG1846@1|root,COG1846@2|Bacteria,1N6YD@1224|Proteobacteria,433TH@68525|delta/epsilon subdivisions,2X3E9@28221|Deltaproteobacteria,2YVPE@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158512_k127_4080365_4	101510.RHA1_ro02542	1.629e-34	136.0	COG0477@1|root,COG2814@2|Bacteria,2GM2G@201174|Actinobacteria,4FXUX@85025|Nocardiaceae	201174|Actinobacteria	EGP	Protein involved in sugar porter activity, transport and response to antibiotic	pcaK	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_4,Sugar_tr
SRR25158512_k127_4080707_0	42256.RradSPS_2290	8.251e-262	815.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CP7K@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
SRR25158512_k127_4080707_2	266117.Rxyl_2875	1.536e-79	268.0	COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria	201174|Actinobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158512_k127_4080707_3	266117.Rxyl_2876	4.537e-67	236.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4CQ59@84995|Rubrobacteria	84995|Rubrobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SRR25158512_k127_4080707_4	1452535.JARD01000018_gene2522	2.46e-16	89.0	COG0454@1|root,COG0456@2|Bacteria,2IEMU@201174|Actinobacteria	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4080707_1	266117.Rxyl_2882	6.804e-130	418.0	COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CPRP@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158512_k127_4091027_3	266117.Rxyl_0016	9.109e-49	176.0	COG4221@1|root,COG4221@2|Bacteria,2I3DT@201174|Actinobacteria	201174|Actinobacteria	S	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158512_k127_4091027_5	469383.Cwoe_3402	8.81e-08	62.0	2B412@1|root,31WRB@2|Bacteria,2HY97@201174|Actinobacteria,4CQGQ@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4091027_1	1111479.AXAR01000006_gene748	1.588e-131	427.0	COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli	91061|Bacilli	F	Pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158512_k127_4091027_0	266117.Rxyl_0019	0.0	1122.0	COG1236@1|root,COG1236@2|Bacteria,2HEXB@201174|Actinobacteria	201174|Actinobacteria	J	Beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
SRR25158512_k127_409171_6	42256.RradSPS_1179	4.111e-23	101.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158512_k127_409171_5	266117.Rxyl_1216	3.516e-53	190.0	COG0432@1|root,COG0432@2|Bacteria,2HNZT@201174|Actinobacteria,4CQ99@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158512_k127_409171_1	266117.Rxyl_1217	3.065e-216	680.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4CPW0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158512_k127_409171_3	266117.Rxyl_1218	3.399e-82	276.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CQIK@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158512_k127_409171_0	42256.RradSPS_1184	6.09e-278	872.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CPUN@84995|Rubrobacteria	84995|Rubrobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C
SRR25158512_k127_409171_4	266117.Rxyl_1220	1.538e-71	244.0	COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria	201174|Actinobacteria	V	Intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158512_k127_4097270_1	266117.Rxyl_1695	1.45e-158	502.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158512_k127_4097270_4	266117.Rxyl_1694	1.077e-93	312.0	COG1335@1|root,COG1335@2|Bacteria,2HEVD@201174|Actinobacteria,4CT0H@84995|Rubrobacteria	84995|Rubrobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158512_k127_4097270_0	42256.RradSPS_1982	1.205e-212	663.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CPTW@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_4097270_3	1278073.MYSTI_03744	7.042e-121	395.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,42TGB@68525|delta/epsilon subdivisions,2WQYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Serine hydrolase involved in the detoxification of formaldehyde	fghA	-	3.1.2.12	ko:K01070,ko:K09795	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	DUF459,Esterase
SRR25158512_k127_4097270_2	479434.Sthe_0784	1.307e-134	441.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi,27Y4R@189775|Thermomicrobia	189775|Thermomicrobia	E	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158512_k127_4097270_6	266117.Rxyl_1677	7.857e-34	138.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158512_k127_4097270_5	266117.Rxyl_1676	2.331e-66	228.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158512_k127_4114560_1	591158.SSMG_01980	3.922e-40	169.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,2H42P@201174|Actinobacteria	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158512_k127_4114560_0	266117.Rxyl_2345	1.285e-200	633.0	COG2267@1|root,COG2267@2|Bacteria,2GNE3@201174|Actinobacteria	201174|Actinobacteria	I	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	3HBOH,Tannase
SRR25158512_k127_4118567_1	266117.Rxyl_1251	8.097e-138	456.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4CTHM@84995|Rubrobacteria	84995|Rubrobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158512_k127_4118567_4	42256.RradSPS_3078	1.959e-34	138.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158512_k127_4118567_2	266117.Rxyl_1618	5.564e-44	164.0	COG2391@1|root,COG2391@2|Bacteria,2I94E@201174|Actinobacteria,4CQVD@84995|Rubrobacteria	84995|Rubrobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158512_k127_4118567_3	266117.Rxyl_1617	2.358e-43	169.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158512_k127_4118567_0	266117.Rxyl_1826	1.309e-199	627.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria,4CQ9I@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158512_k127_412986_4	1122182.KB903813_gene2317	3.235e-20	95.0	COG2020@1|root,COG2020@2|Bacteria,2GTDR@201174|Actinobacteria,4DM6V@85008|Micromonosporales	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158512_k127_412986_5	56780.SYN_02900	4.478e-14	81.0	COG5553@1|root,COG5553@2|Bacteria,1NI0U@1224|Proteobacteria,43160@68525|delta/epsilon subdivisions,2WWEA@28221|Deltaproteobacteria,2MS6U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_412986_1	290399.Arth_2883	4.07e-136	445.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria	201174|Actinobacteria	P	oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158512_k127_412986_0	457429.ABJI02000385_gene4491	3.483e-194	620.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158512_k127_412986_7	1128421.JAGA01000002_gene336	4.166e-06	56.0	COG1807@1|root,COG1807@2|Bacteria,2NS23@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
SRR25158512_k127_412986_2	66897.DJ64_10315	7.651e-98	331.0	COG2230@1|root,COG2230@2|Bacteria,2GKD3@201174|Actinobacteria	201174|Actinobacteria	M	SAM dependent carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_7
SRR25158512_k127_412986_3	42256.RradSPS_2212	1.78e-78	271.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
SRR25158512_k127_412986_6	266117.Rxyl_2219	2.273e-07	58.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4CQMR@84995|Rubrobacteria	84995|Rubrobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158512_k127_4138743_4	485913.Krac_7437	4.153e-81	278.0	COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi	2|Bacteria	G	glycoside hydrolase family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158512_k127_4138743_5	525904.Tter_0582	4.279e-42	158.0	COG0346@1|root,COG0346@2|Bacteria,2NS36@2323|unclassified Bacteria	2|Bacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759,ko:K08234	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158512_k127_4138743_1	405948.SACE_6077	7.206e-142	464.0	COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4EFAI@85010|Pseudonocardiales	201174|Actinobacteria	U	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158512_k127_4138743_6	571166.KI421509_gene4123	9.166e-07	57.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_4138743_3	405948.SACE_3876	2.423e-90	317.0	COG2017@1|root,COG2017@2|Bacteria,2IDCU@201174|Actinobacteria	201174|Actinobacteria	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
SRR25158512_k127_4138743_0	266117.Rxyl_2595	1.489e-173	550.0	COG1482@1|root,COG1482@2|Bacteria,2I8X4@201174|Actinobacteria,4CTUF@84995|Rubrobacteria	84995|Rubrobacteria	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158512_k127_4138743_2	266117.Rxyl_2594	1.401e-124	405.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4CSDU@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158512_k127_4144631_0	1297863.APJF01000020_gene2949	1.161e-103	341.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2TTHB@28211|Alphaproteobacteria,3JSA2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	MA20_01595	-	-	-	-	-	-	-	-	-	-	-	DUF899
SRR25158512_k127_4144631_1	33035.JPJF01000014_gene4755	1.011e-23	112.0	COG1402@1|root,COG1402@2|Bacteria,1TUPT@1239|Firmicutes,259JU@186801|Clostridia,3Y23Z@572511|Blautia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
SRR25158512_k127_4144631_2	765420.OSCT_1961	1.833e-14	75.0	COG1279@1|root,COG1279@2|Bacteria	2|Bacteria	S	arginine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158512_k127_4148957_1	42256.RradSPS_0464	1.278e-20	98.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158512_k127_4148957_0	266117.Rxyl_0458	1.125e-42	167.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4CQKG@84995|Rubrobacteria	84995|Rubrobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158512_k127_4168131_1	266117.Rxyl_2311	3.198e-62	217.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4CQ4H@84995|Rubrobacteria	84995|Rubrobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158512_k127_4168131_0	266117.Rxyl_2310	1.448e-76	261.0	COG0546@1|root,COG0546@2|Bacteria,2I9FC@201174|Actinobacteria,4CTYC@84995|Rubrobacteria	84995|Rubrobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158512_k127_4168131_2	42256.RradSPS_0503	2.262e-28	117.0	COG0520@1|root,COG0520@2|Bacteria,2HP42@201174|Actinobacteria,4CQF7@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
SRR25158512_k127_4179003_6	357808.RoseRS_3883	5.473e-08	53.0	COG2355@1|root,COG2355@2|Bacteria,2G5Y0@200795|Chloroflexi,375WA@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M19 renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158512_k127_4179003_3	1183438.GKIL_4096	4.594e-34	136.0	COG2207@1|root,COG2207@2|Bacteria,1G4YH@1117|Cyanobacteria	1117|Cyanobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SRR25158512_k127_4179003_5	211114.JOEF01000004_gene6689	9.57e-11	67.0	2BHI3@1|root,32BKG@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
SRR25158512_k127_4179003_0	42256.RradSPS_3048	1.24e-100	351.0	COG5002@1|root,COG5002@2|Bacteria,2I4C4@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase- DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158512_k127_4179003_1	42256.RradSPS_3049	1.824e-98	329.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CST2@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_4179003_2	266117.Rxyl_1231	3.5e-86	298.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158512_k127_4179003_4	42256.RradSPS_2247	1.395e-25	119.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158512_k127_4191662_0	635013.TherJR_0948	2.148e-94	323.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,24CJP@186801|Clostridia,260KE@186807|Peptococcaceae	186801|Clostridia	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158512_k127_4191662_1	985762.SAGN_07368	4.048e-37	142.0	COG1742@1|root,COG1742@2|Bacteria,1V6YJ@1239|Firmicutes,4HIIY@91061|Bacilli,4GZDV@90964|Staphylococcaceae	91061|Bacilli	S	UPF0060 membrane protein	yfjF	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
SRR25158512_k127_4191662_2	485913.Krac_6370	6.938e-10	64.0	arCOG13956@1|root,33BWW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_421148_3	266117.Rxyl_1987	3.276e-15	79.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158512_k127_421148_4	42256.RradSPS_1978	3.17e-10	64.0	COG1826@1|root,COG1826@2|Bacteria,2HRTJ@201174|Actinobacteria,4CTX0@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158512_k127_421148_1	266117.Rxyl_1668	1.056e-62	226.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	rskA	GO:0000988,GO:0000989,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010608,GO:0016020,GO:0016989,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158512_k127_421148_0	266117.Rxyl_1667	3.059e-79	268.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4CQ93@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_421148_2	751944.HALDL1_04220	2.553e-58	211.0	arCOG08948@1|root,arCOG08948@2157|Archaea,2XVN3@28890|Euryarchaeota,23URV@183963|Halobacteria	183963|Halobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2,LTD
SRR25158512_k127_4224739_1	1380390.JIAT01000016_gene5600	5.306e-88	294.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CPPE@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158512_k127_4224739_2	109760.SPPG_07972T0	1.474e-28	119.0	2CCRJ@1|root,2S1N8@2759|Eukaryota,3A4FB@33154|Opisthokonta,3P43Z@4751|Fungi	4751|Fungi	S	upf0643 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4224739_0	266117.Rxyl_2025	2.249e-223	702.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
SRR25158512_k127_4226671_7	266117.Rxyl_0094	1.944e-14	79.0	COG2197@1|root,COG2197@2|Bacteria,2IG2E@201174|Actinobacteria	201174|Actinobacteria	KT	COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_4226671_5	1122247.C731_2012	1.626e-28	124.0	2AW9K@1|root,31N50@2|Bacteria,2IP39@201174|Actinobacteria,23AHF@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4226671_4	1336208.JADY01000002_gene560	8.164e-93	312.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,2JV11@204441|Rhodospirillales	204441|Rhodospirillales	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158512_k127_4226671_6	42256.RradSPS_1652	2.156e-16	85.0	COG1925@1|root,COG1925@2|Bacteria,2H0K7@201174|Actinobacteria	201174|Actinobacteria	G	phosphocarrier, HPr family	-	-	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	-	PTS-HPr
SRR25158512_k127_4226671_0	42256.RradSPS_1651	2.118e-215	681.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CPDV@84995|Rubrobacteria	84995|Rubrobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
SRR25158512_k127_4226671_3	266117.Rxyl_1731	2.796e-95	319.0	COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
SRR25158512_k127_4226671_2	1246448.ANAZ01000037_gene81	2.97e-101	340.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4EFK8@85012|Streptosporangiales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_4226671_1	266117.Rxyl_0062	1.016e-133	435.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4CQB2@84995|Rubrobacteria	84995|Rubrobacteria	G	COG COG1653 ABC-type sugar transport system periplasmic component Carbohydrate transport and metabolism	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
SRR25158512_k127_4229546_2	266117.Rxyl_1271	2.567e-132	430.0	COG0168@1|root,COG0168@2|Bacteria,2HNZI@201174|Actinobacteria,4CQ92@84995|Rubrobacteria	84995|Rubrobacteria	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158512_k127_4229546_0	42256.RradSPS_1252	3.134e-191	602.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CPVD@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158512_k127_4229546_1	42256.RradSPS_1251	4.665e-150	478.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158512_k127_4229546_3	266117.Rxyl_0609	6.441e-57	202.0	COG0531@1|root,COG0531@2|Bacteria,2GM81@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4232416_1	1032480.MLP_03070	3.765e-53	200.0	COG1270@1|root,COG1270@2|Bacteria,2GMB8@201174|Actinobacteria,4DNIT@85009|Propionibacteriales	201174|Actinobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
SRR25158512_k127_4232416_0	706587.Desti_5591	2.365e-60	222.0	COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2WJ22@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Aminotran_1_2,CbiA,GATase_3,TP_methylase
SRR25158512_k127_4232416_2	935565.JAEM01000021_gene799	4.426e-26	120.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,2U98X@28211|Alphaproteobacteria,2PUSQ@265|Paracoccus	28211|Alphaproteobacteria	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobP	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
SRR25158512_k127_4232416_3	456442.Mboo_0701	2.914e-12	74.0	COG0368@1|root,arCOG04338@2157|Archaea,2XU3T@28890|Euryarchaeota,2N9QS@224756|Methanomicrobia	224756|Methanomicrobia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158512_k127_4234095_1	266117.Rxyl_1385	1.48e-196	643.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CPIP@84995|Rubrobacteria	84995|Rubrobacteria	D	RecF/RecN/SMC N terminal domain	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158512_k127_4234095_2	42256.RradSPS_1392	2.442e-164	526.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CPF9@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158512_k127_4234095_0	42256.RradSPS_1393	6.122e-240	746.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CP5Y@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158512_k127_4234095_5	266117.Rxyl_1388	2.294e-39	147.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CQNJ@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158512_k127_4234095_6	42256.RradSPS_1395	1.634e-24	104.0	COG1837@1|root,COG1837@2|Bacteria,2HNEK@201174|Actinobacteria,4CQQV@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158512_k127_4234095_4	266117.Rxyl_1390	2.551e-55	199.0	COG0806@1|root,COG0806@2|Bacteria,2HRA2@201174|Actinobacteria,4CT6W@84995|Rubrobacteria	84995|Rubrobacteria	J	RimM N-terminal domain	-	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	RimM
SRR25158512_k127_4234095_3	266117.Rxyl_1391	1.34e-73	250.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CPQ4@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158512_k127_4237103_1	266117.Rxyl_1270	7.623e-38	149.0	COG0010@1|root,COG0010@2|Bacteria,2IJJX@201174|Actinobacteria,4CS3V@84995|Rubrobacteria	84995|Rubrobacteria	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158512_k127_4237103_0	266117.Rxyl_1269	5.557e-240	750.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4CPY9@84995|Rubrobacteria	84995|Rubrobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158512_k127_4238919_3	479434.Sthe_1551	4.731e-35	146.0	COG4585@1|root,COG4585@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
SRR25158512_k127_4238919_2	309807.SRU_0751	1.432e-55	205.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158512_k127_4238919_4	882083.SacmaDRAFT_2354	1.095e-21	101.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DXBN@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_4238919_1	479432.Sros_0274	2.627e-64	226.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4EHWZ@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_4238919_0	42256.RradSPS_0885	2.874e-163	516.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4CRTQ@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese-like domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158512_k127_4238919_5	42256.RradSPS_0886	2.228e-13	70.0	COG0822@1|root,COG0822@2|Bacteria,2HNZE@201174|Actinobacteria,4CQ8X@84995|Rubrobacteria	84995|Rubrobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158512_k127_424567_1	485913.Krac_0986	1.213e-103	342.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
SRR25158512_k127_424567_0	926560.KE387023_gene2289	2.901e-113	379.0	COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158512_k127_4258106_0	266117.Rxyl_2182	9.502e-102	336.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CQ5C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158512_k127_4258106_2	751945.Theos_2027	7.12e-28	121.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SRR25158512_k127_4258106_1	42256.RradSPS_1971	1.676e-59	209.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CPWZ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158512_k127_4258979_2	42256.RradSPS_1820	7.588e-108	353.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CRCP@84995|Rubrobacteria	84995|Rubrobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
SRR25158512_k127_4258979_0	485913.Krac_5427	9.03e-137	445.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158512_k127_4258979_1	42256.RradSPS_1818	3.017e-134	437.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4CQY6@84995|Rubrobacteria	84995|Rubrobacteria	G	Galactokinase galactose-binding signature	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158512_k127_425917_4	525904.Tter_2306	4.697e-26	111.0	COG1785@1|root,COG1785@2|Bacteria,2NPNF@2323|unclassified Bacteria	2|Bacteria	P	Alkaline phosphatase homologues	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
SRR25158512_k127_425917_1	304371.MCP_0108	1.389e-86	297.0	COG0306@1|root,arCOG02267@2157|Archaea,2XSUU@28890|Euryarchaeota,2N9TT@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158512_k127_425917_0	266117.Rxyl_1086	4.244e-205	645.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CPM3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158512_k127_425917_2	266117.Rxyl_1085	7.529e-66	235.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
SRR25158512_k127_425917_3	42256.RradSPS_0951	6.055e-42	156.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4CQPJ@84995|Rubrobacteria	84995|Rubrobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRR25158512_k127_4259453_3	42256.RradSPS_0231	5.743e-85	292.0	COG1898@1|root,COG1898@2|Bacteria,2GMW4@201174|Actinobacteria,4CQ10@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158512_k127_4259453_2	266117.Rxyl_3121	1.82e-160	510.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CPTQ@84995|Rubrobacteria	84995|Rubrobacteria	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158512_k127_4259453_0	266117.Rxyl_3122	1.897e-175	556.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CPRY@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158512_k127_4259453_1	266117.Rxyl_3123	1.105e-170	542.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4CPKK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158512_k127_4283240_2	266117.Rxyl_1644	3.056e-62	217.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CQG3@84995|Rubrobacteria	84995|Rubrobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158512_k127_4283240_4	1449048.JQKU01000022_gene2768	5.523e-44	168.0	COG1309@1|root,COG1309@2|Bacteria,2GNMP@201174|Actinobacteria,232XT@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_4283240_3	886293.Sinac_4765	4.122e-54	211.0	COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes	203682|Planctomycetes	U	Pkd domain containing protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	-
SRR25158512_k127_4283240_1	266117.Rxyl_1647	6.912e-80	270.0	COG2131@1|root,COG2131@2|Bacteria,2IJ94@201174|Actinobacteria	201174|Actinobacteria	F	Deoxycytidylate deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SRR25158512_k127_4283240_0	266117.Rxyl_1648	1.025e-106	349.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CQ1T@84995|Rubrobacteria	84995|Rubrobacteria	F	Uracil phosphoribosyltransferase	-	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158512_k127_4283240_7	266117.Rxyl_1649	1.069e-13	71.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4CPC6@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158512_k127_4301625_1	42256.RradSPS_1990	9.301e-77	261.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpd_1	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158512_k127_4301625_0	266117.Rxyl_2190	3.553e-102	336.0	28NSZ@1|root,2ZBRT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4308964_13	266117.Rxyl_0964	5.184e-53	192.0	COG1035@1|root,COG2878@1|root,COG1035@2|Bacteria,COG2878@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158512_k127_4308964_0	266117.Rxyl_0963	1.863e-285	895.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158512_k127_4308964_7	266117.Rxyl_0962	3.349e-84	286.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,4CQ9K@84995|Rubrobacteria	84995|Rubrobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158512_k127_4308964_3	479434.Sthe_2033	1.042e-102	348.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_4308964_2	266117.Rxyl_0961	4.985e-106	349.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
SRR25158512_k127_4308964_10	266117.Rxyl_0959	6.068e-69	239.0	COG1920@1|root,COG1920@2|Bacteria,2HNVD@201174|Actinobacteria,4CQ43@84995|Rubrobacteria	84995|Rubrobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158512_k127_4308964_1	266117.Rxyl_0958	3.612e-140	451.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4CPHB@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158512_k127_4308964_12	761193.Runsl_2339	1.312e-59	211.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158512_k127_4308964_14	1218076.BAYB01000038_gene5513	2.192e-37	148.0	COG1670@1|root,COG1670@2|Bacteria,1NNQ8@1224|Proteobacteria,2W60F@28216|Betaproteobacteria,1KF0Y@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158512_k127_4308964_11	748727.CLJU_c26770	3.238e-61	221.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,36EQV@31979|Clostridiaceae	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158512_k127_4308964_5	266117.Rxyl_0957	6.66e-93	311.0	COG0095@1|root,COG0095@2|Bacteria,2IG61@201174|Actinobacteria,4CR33@84995|Rubrobacteria	84995|Rubrobacteria	H	Lipoate-protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4308964_9	266117.Rxyl_0955	3.586e-76	260.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria	201174|Actinobacteria	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SRR25158512_k127_4308964_8	266117.Rxyl_0954	2.123e-83	285.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
SRR25158512_k127_4308964_6	266117.Rxyl_0953	4.046e-90	304.0	COG1853@1|root,COG1853@2|Bacteria,2GMPH@201174|Actinobacteria,4CTMQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Flavin reductase like domain	-	-	-	ko:K21185	ko01059,ko01130,map01059,map01130	M00827,M00828,M00832	R11368,R11393	RC00949,RC03431	ko00000,ko00001,ko00002	-	-	-	Flavin_Reduct
SRR25158512_k127_4308964_4	42256.RradSPS_0846	3.043e-93	313.0	COG0500@1|root,COG2226@2|Bacteria,2HENT@201174|Actinobacteria,4CQIJ@84995|Rubrobacteria	84995|Rubrobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158512_k127_4308964_15	266117.Rxyl_0949	3.2e-28	115.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CQ0G@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158512_k127_4311214_3	1298864.AUEQ01000012_gene1031	7.643e-16	78.0	COG2021@1|root,COG2909@1|root,COG2021@2|Bacteria,COG2909@2|Bacteria,2I4HI@201174|Actinobacteria,23F7W@1762|Mycobacteriaceae	201174|Actinobacteria	EK	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
SRR25158512_k127_4311214_1	497964.CfE428DRAFT_0631	8.218e-119	433.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158512_k127_4311214_0	266117.Rxyl_2946	2.291e-139	499.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158512_k127_4311214_2	479434.Sthe_2141	5.675e-95	355.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi	200795|Chloroflexi	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158512_k127_4372615_1	266117.Rxyl_0985	1.444e-134	431.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4CP6Z@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158512_k127_4372615_5	266117.Rxyl_0988	4.742e-45	168.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase,Zn_ribbon_recom
SRR25158512_k127_4372615_4	266117.Rxyl_0989	1.141e-73	255.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc
SRR25158512_k127_4372615_0	42256.RradSPS_0045	7.543e-191	604.0	COG4175@1|root,COG4175@2|Bacteria,2GJC0@201174|Actinobacteria	201174|Actinobacteria	E	glycine betaine	opuAA	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158512_k127_4372615_3	42256.RradSPS_0044	3.122e-88	299.0	COG4176@1|root,COG4176@2|Bacteria,2GKRF@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system permease component	opuAB	-	-	ko:K02001,ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158512_k127_4372615_2	266117.Rxyl_2583	9.819e-101	336.0	COG2113@1|root,COG2113@2|Bacteria,2I2IV@201174|Actinobacteria	201174|Actinobacteria	E	glycine betaine	-	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158512_k127_4372615_6	266117.Rxyl_0669	1.501e-32	130.0	COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4CQB2@84995|Rubrobacteria	84995|Rubrobacteria	G	COG COG1653 ABC-type sugar transport system periplasmic component Carbohydrate transport and metabolism	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
SRR25158512_k127_4380373_0	266117.Rxyl_0187	3.831e-79	268.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CQ94@84995|Rubrobacteria	84995|Rubrobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_4380373_1	179408.Osc7112_4364	7.532e-67	255.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158512_k127_4405666_2	1313172.YM304_02810	1.355e-88	310.0	COG1073@1|root,COG1073@2|Bacteria,2I8SP@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4405666_0	266117.Rxyl_0847	0.0	1122.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	84995|Rubrobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158512_k127_4405666_1	266117.Rxyl_0848	5.281e-111	365.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_4405666_3	266117.Rxyl_0849	1.744e-10	63.0	COG0360@1|root,COG0360@2|Bacteria,2HPGC@201174|Actinobacteria,4CQUW@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein S6	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158512_k127_4410451_8	266117.Rxyl_1466	3.406e-10	62.0	COG1044@1|root,COG1044@2|Bacteria	2|Bacteria	M	lipid A biosynthetic process	neuD	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158512_k127_4410451_3	266117.Rxyl_1467	2.885e-107	356.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CQ89@84995|Rubrobacteria	84995|Rubrobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158512_k127_4410451_5	266117.Rxyl_1468	5.984e-60	214.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CQ1V@84995|Rubrobacteria	84995|Rubrobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158512_k127_4410451_1	266117.Rxyl_1469	1.2e-195	634.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4CPGM@84995|Rubrobacteria	84995|Rubrobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158512_k127_4410451_0	266117.Rxyl_1470	1.455e-219	698.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CPIK@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158512_k127_4410451_2	266117.Rxyl_1471	4.99e-111	370.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CQAJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158512_k127_4410451_7	266117.Rxyl_1472	1.439e-36	141.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4CQGS@84995|Rubrobacteria	84995|Rubrobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158512_k127_4410451_4	266117.Rxyl_1473	8.411e-82	281.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158512_k127_4410451_6	266117.Rxyl_1474	4.692e-48	174.0	2AU98@1|root,31JWM@2|Bacteria,2HNY8@201174|Actinobacteria,4CQ7F@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4419948_1	344747.PM8797T_13620	1.322e-58	214.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158512_k127_4419948_2	1030157.AFMP01000014_gene3410	3.45e-47	172.0	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,2UAPG@28211|Alphaproteobacteria,2K5QA@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158512_k127_4419948_0	309807.SRU_2444	1.915e-222	704.0	COG1053@1|root,COG1053@2|Bacteria,4NHXK@976|Bacteroidetes,1FJ4E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158512_k127_4419965_1	266117.Rxyl_3178	9.637e-193	609.0	COG1164@1|root,COG1164@2|Bacteria,2HDPQ@201174|Actinobacteria,4CTTS@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
SRR25158512_k127_4419965_2	204669.Acid345_2084	1.62e-116	384.0	COG1171@1|root,COG1171@2|Bacteria,3Y2UN@57723|Acidobacteria,2JI1Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158512_k127_4419965_4	118168.MC7420_1742	1.686e-91	313.0	COG3217@1|root,COG3217@2|Bacteria,1G41J@1117|Cyanobacteria,1HA5C@1150|Oscillatoriales	1117|Cyanobacteria	S	Fe-S protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
SRR25158512_k127_4419965_7	1476876.JOJO01000030_gene3184	9.017e-37	145.0	COG0454@1|root,COG0456@2|Bacteria,2INHM@201174|Actinobacteria	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4419965_0	390989.JOEG01000014_gene3103	2.843e-206	656.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4DAC0@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158512_k127_4419965_3	266117.Rxyl_3180	1.046e-99	334.0	COG0454@1|root,COG0456@2|Bacteria,2HPI4@201174|Actinobacteria,4CQVU@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4419965_5	266117.Rxyl_3181	1.349e-71	244.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CU2F@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_4438541_2	266117.Rxyl_0826	1.187e-13	70.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,2IG04@201174|Actinobacteria,4CPK0@84995|Rubrobacteria	84995|Rubrobacteria	CK	DHHA2	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
SRR25158512_k127_4438541_1	1005048.CFU_1955	1.583e-103	358.0	COG4292@1|root,COG4292@2|Bacteria,1MW5F@1224|Proteobacteria,2VMW0@28216|Betaproteobacteria,4731I@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Bacterial low temperature requirement A protein (LtrA)	ltrA	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158512_k127_4438541_0	266117.Rxyl_0825	0.0	1073.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158512_k127_4441961_0	266117.Rxyl_1652	1.539e-177	561.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CP8A@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158512_k127_4441961_2	266117.Rxyl_1651	9.232e-118	387.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CQFI@84995|Rubrobacteria	84995|Rubrobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158512_k127_4441961_3	266117.Rxyl_1650	3.243e-67	235.0	COG0009@1|root,COG0009@2|Bacteria,2HPE4@201174|Actinobacteria,4CQS7@84995|Rubrobacteria	84995|Rubrobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158512_k127_4441961_1	485913.Krac_2227	1.178e-126	412.0	COG0454@1|root,COG1846@1|root,COG0454@2|Bacteria,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ybfA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,MarR_2
SRR25158512_k127_4441961_4	2045.KR76_07600	7.42e-55	205.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4DP8M@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158512_k127_4441961_5	1487921.DP68_14070	0.0002758	45.0	29QV6@1|root,30BVB@2|Bacteria,1U8PC@1239|Firmicutes,252MJ@186801|Clostridia,36SRQ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4446944_2	42256.RradSPS_0051	3.644e-23	100.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2,HTH_36
SRR25158512_k127_4446944_0	266117.Rxyl_0041	5.738e-119	388.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria,4CQKR@84995|Rubrobacteria	84995|Rubrobacteria	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
SRR25158512_k127_4446944_1	42256.RradSPS_0053	7.262e-82	277.0	2AS5P@1|root,31HIK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4446944_3	266117.Rxyl_2376	3.57e-21	98.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4CQPE@84995|Rubrobacteria	84995|Rubrobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
SRR25158512_k127_4454529_6	118163.Ple7327_3871	4.134e-34	132.0	COG3609@1|root,COG3609@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
SRR25158512_k127_4454529_3	42256.RradSPS_2166	1.887e-111	369.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158512_k127_4454529_4	1380370.JIBA01000015_gene298	2.876e-82	286.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_4454529_1	42256.RradSPS_2160	2.713e-152	489.0	COG0287@1|root,COG4747@1|root,COG0287@2|Bacteria,COG4747@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158512_k127_4454529_0	42256.RradSPS_2159	1.722e-164	523.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,4CPIS@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158512_k127_4454529_7	266117.Rxyl_0727	2.458e-32	128.0	COG1605@1|root,COG1605@2|Bacteria,2HDDB@201174|Actinobacteria	201174|Actinobacteria	E	Chorismate mutase type II	-	-	-	-	-	-	-	-	-	-	-	-	CM_2
SRR25158512_k127_4454529_2	266117.Rxyl_0728	1.826e-133	430.0	COG2876@1|root,COG2876@2|Bacteria,2I3UA@201174|Actinobacteria,4CPFQ@84995|Rubrobacteria	84995|Rubrobacteria	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158512_k127_4454529_5	266117.Rxyl_0729	9.286e-68	234.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CU1S@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158512_k127_4456987_6	266117.Rxyl_1491	5.898e-35	139.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	ko:K01921,ko:K03589	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158512_k127_4456987_0	266117.Rxyl_1492	9.139e-211	662.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CPYN@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158512_k127_4456987_5	1396141.BATP01000041_gene2221	5.368e-42	169.0	COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia,2ITPN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	-	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158512_k127_4456987_3	266117.Rxyl_1494	2.282e-145	470.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CSTK@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158512_k127_4456987_1	266117.Rxyl_1495	8.151e-164	530.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CQ2K@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158512_k127_4456987_4	235909.GK1117	5.081e-81	280.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,1WEB0@129337|Geobacillus	91061|Bacilli	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
SRR25158512_k127_4456987_2	266117.Rxyl_1497	1.221e-163	522.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CPND@84995|Rubrobacteria	84995|Rubrobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158512_k127_4469077_4	266117.Rxyl_2115	8.054e-120	387.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CPNJ@84995|Rubrobacteria	84995|Rubrobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158512_k127_4469077_5	266117.Rxyl_1997	7.188e-90	304.0	COG0454@1|root,COG0456@2|Bacteria,2I4BM@201174|Actinobacteria,4CQBU@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4469077_6	266117.Rxyl_2113	1.372e-83	288.0	COG0344@1|root,COG0344@2|Bacteria,2IF8Y@201174|Actinobacteria,4CTSY@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158512_k127_4469077_0	266117.Rxyl_2112	0.0	1144.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CRTI@84995|Rubrobacteria	84995|Rubrobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,HAD,NAD_binding_4
SRR25158512_k127_4469077_2	266117.Rxyl_2111	3.478e-189	598.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_4469077_1	266117.Rxyl_2107	2.184e-277	859.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158512_k127_4469077_3	266117.Rxyl_0507	2.864e-133	436.0	COG0477@1|root,COG2814@2|Bacteria,2I4BU@201174|Actinobacteria,4CTFA@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_4469077_8	760568.Desku_3213	4.365e-12	66.0	COG5483@1|root,COG5483@2|Bacteria,1VA74@1239|Firmicutes,24PPB@186801|Clostridia,26608@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158512_k127_4500857_0	266117.Rxyl_0799	6.596e-263	825.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CPJN@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158512_k127_4500857_6	42256.RradSPS_0673	2.119e-74	264.0	COG3503@1|root,COG3503@2|Bacteria,2IJR9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
SRR25158512_k127_4500857_8	266117.Rxyl_0798	2.063e-66	229.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4500857_13	42256.RradSPS_0671	1.183e-32	134.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
SRR25158512_k127_4500857_2	266117.Rxyl_0796	1.279e-166	528.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4CPJX@84995|Rubrobacteria	84995|Rubrobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158512_k127_4500857_5	266117.Rxyl_0795	1.947e-88	303.0	COG1039@1|root,COG1039@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhC	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF3378,RNase_HII
SRR25158512_k127_4500857_14	266117.Rxyl_0794	7.657e-29	118.0	COG1254@1|root,COG1254@2|Bacteria,2IT6J@201174|Actinobacteria,4CTJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158512_k127_4500857_1	266117.Rxyl_0793	1.93e-234	734.0	COG0463@1|root,COG2203@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2203@2|Bacteria,COG2246@2|Bacteria,2I4BA@201174|Actinobacteria,4CU4V@84995|Rubrobacteria	84995|Rubrobacteria	MT	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
SRR25158512_k127_4500857_3	266117.Rxyl_0791	3.775e-110	367.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4CPVH@84995|Rubrobacteria	84995|Rubrobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158512_k127_4500857_7	266117.Rxyl_0789	5.429e-69	238.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4500857_11	266117.Rxyl_0788	2.086e-57	205.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,Peptidase_C39_2,TPR_16,TPR_2,TPR_4,TPR_8
SRR25158512_k127_4500857_12	266117.Rxyl_0787	1.623e-53	194.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CQCY@84995|Rubrobacteria	84995|Rubrobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158512_k127_4500857_4	471852.Tcur_0236	1.255e-89	307.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4EHSG@85012|Streptosporangiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158512_k127_4500857_9	266117.Rxyl_0785	4.763e-63	219.0	COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CQBV@84995|Rubrobacteria	84995|Rubrobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158512_k127_4502610_3	266117.Rxyl_0524	1.623e-50	183.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158512_k127_4502610_0	882082.SaccyDRAFT_4653	3.094e-183	588.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4E6EC@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158512_k127_4502610_1	266117.Rxyl_0283	7.023e-135	438.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158512_k127_4502610_2	192952.MM_0529	1.028e-71	252.0	COG0596@1|root,arCOG01648@2157|Archaea,2XUZM@28890|Euryarchaeota,2NB9P@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158512_k127_4502610_4	441620.Mpop_3009	7.583e-32	126.0	COG1285@1|root,COG1285@2|Bacteria,1RAEY@1224|Proteobacteria,2U6IN@28211|Alphaproteobacteria,1JQPY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158512_k127_4514092_1	266117.Rxyl_1069	5.192e-237	746.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4CSAD@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
SRR25158512_k127_4514092_4	405948.SACE_2599	9.683e-168	539.0	COG2270@1|root,COG2270@2|Bacteria,2I65Y@201174|Actinobacteria,4EE3W@85010|Pseudonocardiales	201174|Actinobacteria	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_4514092_2	42256.RradSPS_3023	2.567e-228	721.0	COG1069@1|root,COG1069@2|Bacteria,2I41D@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the FGGY kinase family	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_4514092_3	42256.RradSPS_3030	3.173e-189	601.0	COG0371@1|root,COG0371@2|Bacteria,2HRTP@201174|Actinobacteria,4CTX5@84995|Rubrobacteria	84995|Rubrobacteria	C	COG COG0371 Glycerol dehydrogenase and related enzymes Energy production and conversion	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
SRR25158512_k127_4514092_0	42256.RradSPS_3032	4.438e-250	788.0	COG1069@1|root,COG1069@2|Bacteria,2I41D@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the FGGY kinase family	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_4514092_5	42256.RradSPS_3029	2.287e-134	434.0	COG0647@1|root,COG0647@2|Bacteria,2HG8I@201174|Actinobacteria,4CTX4@84995|Rubrobacteria	84995|Rubrobacteria	G	HAD-superfamily hydrolase, subfamily IIA	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158512_k127_4514092_6	42256.RradSPS_3031	4.85e-66	228.0	COG0698@1|root,COG0698@2|Bacteria,2IIDQ@201174|Actinobacteria,4CU5Q@84995|Rubrobacteria	84995|Rubrobacteria	G	Sugar-phosphate isomerase, RpiB LacA LacB family	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158512_k127_4525356_13	402777.KB235903_gene1642	1.393e-13	74.0	2EFXV@1|root,339Q3@2|Bacteria,1GA81@1117|Cyanobacteria	1117|Cyanobacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4525356_14	768706.Desor_3767	2.846e-12	72.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,254A7@186801|Clostridia,266ED@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM TOMM propeptide domain	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4525356_12	102129.Lepto7375DRAFT_1972	1.442e-14	85.0	2EB14@1|root,3351Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4525356_8	1120998.AUFC01000012_gene477	9.286e-49	184.0	COG0845@1|root,COG0845@2|Bacteria,1V0EP@1239|Firmicutes,24DYZ@186801|Clostridia	186801|Clostridia	M	TIGRFAM NHLM bacteriocin system secretion protein	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158512_k127_4525356_0	485916.Dtox_0939	1.299e-280	881.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,261EJ@186807|Peptococcaceae	186801|Clostridia	V	NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
SRR25158512_k127_4525356_2	767817.Desgi_2846	6.574e-232	752.0	COG2274@1|root,COG2274@2|Bacteria,1TRMR@1239|Firmicutes,248Z2@186801|Clostridia,261E8@186807|Peptococcaceae	186801|Clostridia	P	NHLM bacteriocin system ABC transporter, ATP-binding protein	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
SRR25158512_k127_4525356_7	1173020.Cha6605_4114	4.272e-69	248.0	COG3751@1|root,COG3751@2|Bacteria,1G31S@1117|Cyanobacteria	1117|Cyanobacteria	O	SMART Prolyl 4-hydroxylase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
SRR25158512_k127_4525356_15	1173024.KI912149_gene6521	4.162e-11	69.0	2EFXV@1|root,339Q3@2|Bacteria,1GA81@1117|Cyanobacteria	1117|Cyanobacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4525356_5	1173024.KI912149_gene6516	5.479e-134	437.0	28JGA@1|root,2Z9A3@2|Bacteria,1G1Q6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4525356_16	1048983.EL17_14465	2.923e-10	72.0	COG1216@1|root,COG1216@2|Bacteria,4NKMR@976|Bacteroidetes,47TGR@768503|Cytophagia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
SRR25158512_k127_4525356_11	1173024.KI912149_gene6521	2.226e-17	86.0	2EFXV@1|root,339Q3@2|Bacteria,1GA81@1117|Cyanobacteria	1117|Cyanobacteria	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4525356_4	1173020.Cha6605_4115	3.114e-142	469.0	2CB6F@1|root,2ZAB0@2|Bacteria,1G4XW@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4525356_1	1173024.KI912149_gene6520	7.249e-276	884.0	COG4403@1|root,COG4403@2|Bacteria,1G04S@1117|Cyanobacteria,1JH1I@1189|Stigonemataceae	1117|Cyanobacteria	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
SRR25158512_k127_4525356_17	1284352.AOIG01000004_gene1220	6.251e-06	51.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,4I26M@91061|Bacilli,2705Y@186822|Paenibacillaceae	91061|Bacilli	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4525356_6	755178.Cyan10605_1048	1.518e-88	305.0	2CB6F@1|root,2ZAB0@2|Bacteria,1G4XW@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4525356_3	485913.Krac_4298	5.898e-185	587.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	xyoA	-	1.1.3.41,1.1.3.8	ko:K00103,ko:K00594	ko00040,ko00051,ko00053,ko01100,map00040,map00051,map00053,map01100	M00129	R00647,R03184,R07152,R10053,R11620	RC00108,RC00133,RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
SRR25158512_k127_4525356_9	266117.Rxyl_1776	1.726e-34	137.0	COG1707@1|root,COG1707@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
SRR25158512_k127_4527262_4	1217718.ALOU01000032_gene1374	8.862e-20	89.0	COG0824@1|root,COG0824@2|Bacteria,1RGZN@1224|Proteobacteria,2VREZ@28216|Betaproteobacteria,1K703@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158512_k127_4527262_0	1156844.KB891831_gene4702	1.574e-39	155.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4527262_3	1120949.KB903295_gene2534	1.148e-30	124.0	29JYD@1|root,306VN@2|Bacteria,2GWXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4527262_2	1437882.AZRU01000078_gene4012	2.686e-36	147.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,1SAIB@1236|Gammaproteobacteria,1YIKM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158512_k127_4527262_1	322710.Avin_32910	3.791e-38	148.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158512_k127_4550181_3	266117.Rxyl_1453	1.915e-29	118.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CPSV@84995|Rubrobacteria	84995|Rubrobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158512_k127_4550181_5	42256.RradSPS_0946	8.313e-18	88.0	COG2197@1|root,COG2197@2|Bacteria,2IHF7@201174|Actinobacteria,4CRGW@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_4550181_4	42256.RradSPS_0946	3.131e-24	105.0	COG2197@1|root,COG2197@2|Bacteria,2IHF7@201174|Actinobacteria,4CRGW@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_4550181_0	266117.Rxyl_1448	4.587e-303	934.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CPN2@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158512_k127_4550181_1	266117.Rxyl_1445	3.745e-162	518.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4CRZC@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158512_k127_4550181_2	266117.Rxyl_1444	4.972e-37	151.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4CQNN@84995|Rubrobacteria	84995|Rubrobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158512_k127_4556441_2	937777.Deipe_0616	2.242e-38	164.0	COG0028@1|root,COG3055@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4,4.1.3.1	ko:K01179,ko:K01637	ko00500,ko00630,ko01100,ko01110,ko01120,ko01200,map00500,map00630,map01100,map01110,map01120,map01200	M00012	R00479,R06200,R11307,R11308	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin,PKD,TIG
SRR25158512_k127_4556441_1	1192124.LIG30_0882	1.088e-46	190.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VWW5@28216|Betaproteobacteria,1K6BN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SRR25158512_k127_4556441_0	420324.KI911956_gene3390	1.309e-159	509.0	COG2141@1|root,COG2141@2|Bacteria,1MUTJ@1224|Proteobacteria,2TTZI@28211|Alphaproteobacteria,1JU1Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_4560444_1	266117.Rxyl_0997	2.836e-121	392.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CPN1@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158512_k127_4560444_3	1210884.HG799465_gene12237	6.576e-50	183.0	COG0662@1|root,COG0662@2|Bacteria,2J42S@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_4560444_0	266117.Rxyl_0996	0.0	1095.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4CP9W@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158512_k127_4560444_2	266117.Rxyl_0995	4.213e-121	391.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4CPW1@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158512_k127_4560444_4	42256.RradSPS_0908	4.961e-13	68.0	COG1828@1|root,COG1828@2|Bacteria,2HP8J@201174|Actinobacteria,4CQKK@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158512_k127_4561606_0	42256.RradSPS_1800	1.798e-267	828.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CPEX@84995|Rubrobacteria	84995|Rubrobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158512_k127_4561606_6	266117.Rxyl_2020	5.464e-53	199.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158512_k127_4561606_5	42256.RradSPS_1799	1.69e-74	256.0	COG1309@1|root,COG1309@2|Bacteria,2HH4Q@201174|Actinobacteria,4CTMY@84995|Rubrobacteria	84995|Rubrobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158512_k127_4561606_4	1121440.AUMA01000010_gene328	2.288e-119	398.0	28HAQ@1|root,2Z7N0@2|Bacteria,1N5R2@1224|Proteobacteria,42YEC@68525|delta/epsilon subdivisions,2WTJ4@28221|Deltaproteobacteria,2MB66@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
SRR25158512_k127_4561606_1	266117.Rxyl_2018	1.621e-246	767.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CP60@84995|Rubrobacteria	84995|Rubrobacteria	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158512_k127_4561606_2	266117.Rxyl_2017	2.598e-226	719.0	COG2508@1|root,COG2508@2|Bacteria,2HJJI@201174|Actinobacteria,4CPT6@84995|Rubrobacteria	84995|Rubrobacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158512_k127_4561606_3	42256.RradSPS_1794	2.111e-172	545.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158512_k127_4562465_0	266117.Rxyl_2294	1.597e-181	573.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4CU40@84995|Rubrobacteria	84995|Rubrobacteria	M	Cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
SRR25158512_k127_4562465_3	266117.Rxyl_2295	1.292e-38	145.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CQN4@84995|Rubrobacteria	84995|Rubrobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158512_k127_4562465_2	42256.RradSPS_0519	3.272e-47	172.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4CQED@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158512_k127_4562465_1	266117.Rxyl_2297	1.937e-141	455.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4CQ17@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158512_k127_4562465_4	266117.Rxyl_2298	3.988e-10	61.0	COG1686@1|root,COG1686@2|Bacteria,2GJ7C@201174|Actinobacteria,4CP6F@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158512_k127_4567260_1	42256.RradSPS_1546	7.974e-247	764.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CPB5@84995|Rubrobacteria	84995|Rubrobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158512_k127_4567260_0	266117.Rxyl_1535	0.0	1402.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CPR8@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158512_k127_4567260_2	266117.Rxyl_1534	2.296e-114	392.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CQ90@84995|Rubrobacteria	84995|Rubrobacteria	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158512_k127_4570425_4	326424.FRAAL1424	2.126e-63	228.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158512_k127_4570425_1	266117.Rxyl_3089	8.937e-150	490.0	COG2141@1|root,COG2141@2|Bacteria,2GJ66@201174|Actinobacteria,4CPW3@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_4570425_3	266117.Rxyl_1071	1.067e-130	424.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4CPX4@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_4570425_2	42256.RradSPS_2521	4.145e-145	471.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4CS6S@84995|Rubrobacteria	84995|Rubrobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
SRR25158512_k127_4570425_0	42256.RradSPS_0340	4.423e-202	632.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4CPUF@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158512_k127_457176_0	266117.Rxyl_2444	1.644e-190	604.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CP73@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158512_k127_457176_2	118173.KB235914_gene2745	7.752e-21	101.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
SRR25158512_k127_457176_1	525904.Tter_2859	5.151e-174	584.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,NB-ARC,Pkinase,TPR_10,TPR_12,Trans_reg_C
SRR25158512_k127_4574265_0	266117.Rxyl_0775	1.42e-262	812.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CP9U@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158512_k127_4574265_1	266117.Rxyl_0773	3.022e-260	810.0	COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158512_k127_4574265_2	266117.Rxyl_0772	6.778e-161	512.0	COG2129@1|root,COG2129@2|Bacteria,2IJW1@201174|Actinobacteria,4CQ37@84995|Rubrobacteria	84995|Rubrobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4579980_5	266117.Rxyl_2989	8.675e-73	258.0	COG3395@1|root,COG3395@2|Bacteria,2HRX3@201174|Actinobacteria,4CU08@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
SRR25158512_k127_4579980_3	266117.Rxyl_2988	1.649e-149	486.0	COG1995@1|root,COG1995@2|Bacteria,2GRPG@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158512_k127_4579980_2	266117.Rxyl_2987	2.782e-157	506.0	COG2768@1|root,COG2768@2|Bacteria,2I5Q6@201174|Actinobacteria	201174|Actinobacteria	C	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158512_k127_4579980_4	1499967.BAYZ01000159_gene491	1.517e-102	340.0	COG1878@1|root,COG1878@2|Bacteria,2NQ0H@2323|unclassified Bacteria	2|Bacteria	S	Putative cyclase	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.1.1.363,1.1.1.49,3.5.1.9	ko:K00036,ko:K07130	ko00030,ko00380,ko00480,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00380,map00480,map00630,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008,M00038	R00835,R00988,R01959,R02736,R04911,R10907	RC00001,RC00066,RC00263,RC00323	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cyclase
SRR25158512_k127_4579980_7	345341.KUTG_02072	4.603e-29	120.0	COG0251@1|root,COG0251@2|Bacteria,2IHP3@201174|Actinobacteria,4E5PH@85010|Pseudonocardiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158512_k127_4579980_0	266117.Rxyl_2986	1.585e-179	571.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CQ5A@84995|Rubrobacteria	84995|Rubrobacteria	H	molybdopterin binding domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158512_k127_4579980_6	42256.RradSPS_0254	5.851e-42	159.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,4CQ82@84995|Rubrobacteria	84995|Rubrobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
SRR25158512_k127_4587242_3	324602.Caur_3138	1.308e-07	59.0	2A5RH@1|root,30UGG@2|Bacteria,2GAGV@200795|Chloroflexi,3762W@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
SRR25158512_k127_4587242_1	1229172.JQFA01000002_gene3797	1.3e-53	193.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158512_k127_4587242_2	1380347.JNII01000008_gene4406	7.76e-20	96.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4EWV7@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4587242_0	1123023.JIAI01000001_gene7712	1.661e-120	402.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,4E0ET@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158512_k127_4588765_13	42256.RradSPS_0227	3.964e-17	81.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4CPKK@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158512_k127_4588765_6	266117.Rxyl_3124	8.896e-136	439.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CQEJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158512_k127_4588765_11	485913.Krac_10524	1.557e-51	186.0	2CRSQ@1|root,30IRU@2|Bacteria,2G9M6@200795|Chloroflexi	200795|Chloroflexi	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158512_k127_4588765_15	1209989.TepiRe1_0588	2.957e-16	80.0	COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,24AKC@186801|Clostridia,42FPX@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acetamidase Formamidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR25158512_k127_4588765_16	1380394.JADL01000008_gene3603	4.095e-08	58.0	COG2421@1|root,COG2421@2|Bacteria,1MXKY@1224|Proteobacteria,2TSVA@28211|Alphaproteobacteria,2JR7H@204441|Rhodospirillales	204441|Rhodospirillales	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
SRR25158512_k127_4588765_9	1173024.KI912153_gene37	6.909e-55	203.0	COG4977@1|root,COG4977@2|Bacteria,1G1HG@1117|Cyanobacteria	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SRR25158512_k127_4588765_7	13035.Dacsa_2593	1.468e-91	339.0	COG3210@1|root,COG3210@2|Bacteria,1GPZ7@1117|Cyanobacteria	2|Bacteria	U	Parallel beta-helix repeats	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Laminin_G_3
SRR25158512_k127_4588765_14	1380390.JIAT01000009_gene822	2.519e-16	94.0	2DP3A@1|root,330CA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Gly_rich,Mfa_like_1
SRR25158512_k127_4588765_10	929556.Solca_0050	2.04e-52	210.0	COG1470@1|root,COG3209@1|root,COG4932@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia	976|Bacteroidetes	M	conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
SRR25158512_k127_4588765_0	266117.Rxyl_3125	1.782e-307	948.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CPN4@84995|Rubrobacteria	84995|Rubrobacteria	E	Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158512_k127_4588765_3	266117.Rxyl_3127	3.41e-176	556.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CPA6@84995|Rubrobacteria	84995|Rubrobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158512_k127_4588765_4	266117.Rxyl_3128	4.78e-163	517.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CPCQ@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158512_k127_4588765_1	266117.Rxyl_3129	1.311e-280	869.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CP5R@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158512_k127_4588765_8	42256.RradSPS_0214	6.22e-67	242.0	290GX@1|root,2ZN5X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4588765_5	266117.Rxyl_3130	1.955e-154	503.0	COG0473@1|root,COG0473@2|Bacteria,2HABY@201174|Actinobacteria,4CPBV@84995|Rubrobacteria	84995|Rubrobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158512_k127_4588765_2	266117.Rxyl_3131	2.571e-271	842.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,4CPIA@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158512_k127_4601317_1	469383.Cwoe_1072	3.019e-128	417.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4CRKJ@84995|Rubrobacteria	84995|Rubrobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18
SRR25158512_k127_4601317_0	1237149.C900_02066	2.274e-145	480.0	COG0076@1|root,COG0076@2|Bacteria,4NGZB@976|Bacteroidetes	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
SRR25158512_k127_4601317_2	1121017.AUFG01000006_gene1094	3.356e-06	51.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria,4FHJZ@85021|Intrasporangiaceae	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158512_k127_4603259_1	42256.RradSPS_1671	1.668e-128	424.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CR9E@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158512_k127_4603259_2	1121124.JNIX01000016_gene2096	2.157e-13	74.0	2EBHU@1|root,335I9@2|Bacteria,1N2MU@1224|Proteobacteria,2UDTV@28211|Alphaproteobacteria,2KJ32@204458|Caulobacterales	204458|Caulobacterales	S	REDY-like protein HapK	-	-	-	-	-	-	-	-	-	-	-	-	HapK
SRR25158512_k127_4603259_0	1183438.GKIL_0560	7.309e-138	453.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158512_k127_4611025_0	765420.OSCT_1132	4.118e-128	415.0	COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_4611025_3	44060.JODL01000002_gene2173	1.723e-48	178.0	294UC@1|root,2ZS7I@2|Bacteria,2III4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SRR25158512_k127_4611025_2	909613.UO65_5046	1.313e-58	208.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria,4E380@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158512_k127_4611025_4	1380390.JIAT01000013_gene308	1.918e-48	177.0	COG0640@1|root,COG0640@2|Bacteria,2HFRM@201174|Actinobacteria,4CT8Z@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158512_k127_4611025_1	42256.RradSPS_1684	1.022e-117	390.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CPQ3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_4613034_1	266117.Rxyl_1117	1.165e-130	424.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CQ2R@84995|Rubrobacteria	84995|Rubrobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SRR25158512_k127_4613034_2	266117.Rxyl_1116	1.959e-122	399.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4CPJK@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158512_k127_4613034_3	42256.RradSPS_1107	1.374e-88	296.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	ags	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158512_k127_4613034_0	266117.Rxyl_1114	1.228e-149	484.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	mhpC	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016822,GO:0016823,GO:0030312,GO:0034820,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	3.7.1.13,3.7.1.14,3.7.1.17,3.7.1.9	ko:K05714,ko:K10216,ko:K10702,ko:K15756,ko:K16050,ko:K18092	ko00360,ko00362,ko00621,ko00622,ko00642,ko00643,ko00984,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map00642,map00643,map00984,map01100,map01120,map01220	M00544,M00545,M00569	R02603,R02604,R05138,R05362,R05365,R05366,R05865,R06789,R09883	RC00272,RC00752,RC00753,RC00754,RC00755,RC00757,RC01277,RC01337,RC01485,RC02018,RC02740	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158512_k127_4621214_4	1121377.KB906398_gene2593	1.743e-35	136.0	COG1028@1|root,COG1028@2|Bacteria,1WJW2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_4621214_0	479434.Sthe_2955	1.242e-181	576.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_4621214_5	404589.Anae109_0580	9.459e-35	137.0	COG3795@1|root,COG3795@2|Bacteria,1Q42B@1224|Proteobacteria,439VS@68525|delta/epsilon subdivisions,2X59V@28221|Deltaproteobacteria,2Z0B4@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158512_k127_4621214_2	479432.Sros_6982	1.389e-63	233.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4EJS4@85012|Streptosporangiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158512_k127_4621214_1	479432.Sros_4134	8.847e-98	329.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4EJ5F@85012|Streptosporangiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_4621214_3	485913.Krac_0922	5.434e-40	153.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_4622577_0	42256.RradSPS_1332	1.315e-262	814.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CPMB@84995|Rubrobacteria	84995|Rubrobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158512_k127_4622577_1	266117.Rxyl_1337	5.642e-261	813.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CR6S@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
SRR25158512_k127_4622577_2	266117.Rxyl_1336	2.161e-46	173.0	COG3937@1|root,COG3937@2|Bacteria	2|Bacteria	-	-	phaI	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRR25158512_k127_4622577_3	266117.Rxyl_1335	1.536e-07	53.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4CU2V@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
SRR25158512_k127_462789_1	266117.Rxyl_0636	1.5e-98	330.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,2GN3S@201174|Actinobacteria,4CPDF@84995|Rubrobacteria	84995|Rubrobacteria	H	Magnesium chelatase, subunit ChlI	-	-	6.6.1.1	ko:K03404	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase,VWA_2
SRR25158512_k127_462789_0	266117.Rxyl_0638	2.466e-194	615.0	COG1797@1|root,COG1797@2|Bacteria,2GJ3R@201174|Actinobacteria,4CPJ6@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	-	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
SRR25158512_k127_462789_2	266117.Rxyl_0639	4.485e-95	320.0	COG2243@1|root,COG2243@2|Bacteria,2GUI0@201174|Actinobacteria,4CPYP@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
SRR25158512_k127_4636149_4	42256.RradSPS_1430	2.82e-32	125.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4CS83@84995|Rubrobacteria	84995|Rubrobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158512_k127_4636149_2	266117.Rxyl_1426	1.227e-93	316.0	COG0323@1|root,COG0323@2|Bacteria,2H8CS@201174|Actinobacteria	201174|Actinobacteria	L	histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_3
SRR25158512_k127_4636149_0	266117.Rxyl_1427	3.581e-235	734.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CPXU@84995|Rubrobacteria	84995|Rubrobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158512_k127_4636149_3	266117.Rxyl_1428	1.109e-85	295.0	COG0324@1|root,COG0324@2|Bacteria	2|Bacteria	J	tRNA dimethylallyltransferase activity	-	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	DUF222,IPPT
SRR25158512_k127_4636149_1	266117.Rxyl_1429	1.06e-160	516.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CPXQ@84995|Rubrobacteria	84995|Rubrobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158512_k127_4641481_7	357808.RoseRS_2735	4.43e-28	117.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi,376HX@32061|Chloroflexia	32061|Chloroflexia	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
SRR25158512_k127_4641481_2	266117.Rxyl_1685	3.14e-193	616.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4CPQB@84995|Rubrobacteria	84995|Rubrobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158512_k127_4641481_0	266117.Rxyl_1684	6.785e-229	720.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4CP7R@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
SRR25158512_k127_4641481_5	266117.Rxyl_1683	1.81e-131	427.0	COG1172@1|root,COG1172@2|Bacteria,2GM6S@201174|Actinobacteria,4CS8A@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10560	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
SRR25158512_k127_4641481_4	266117.Rxyl_1682	1.035e-135	453.0	COG1172@1|root,COG1172@2|Bacteria,2GM2F@201174|Actinobacteria,4CU4A@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
SRR25158512_k127_4641481_3	266117.Rxyl_1681	2.318e-167	531.0	COG1879@1|root,COG1879@2|Bacteria,2I43Z@201174|Actinobacteria,4CPWY@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10559	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	Peripla_BP_4
SRR25158512_k127_4641481_1	266117.Rxyl_1680	9.92e-204	640.0	COG4952@1|root,COG4952@2|Bacteria,2GK1Z@201174|Actinobacteria,4CPHU@84995|Rubrobacteria	84995|Rubrobacteria	M	L-rhamnose isomerase (RhaA)	-	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	RhaA
SRR25158512_k127_4641481_6	266117.Rxyl_1679	6.459e-35	135.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria,4CPA5@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158512_k127_4652925_2	1120973.AQXL01000103_gene2508	6.666e-84	285.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,278R9@186823|Alicyclobacillaceae	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158512_k127_4652925_0	1380347.JNII01000005_gene3392	4.183e-242	762.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158512_k127_4652925_1	266117.Rxyl_0871	1.657e-117	384.0	COG3342@1|root,COG3342@2|Bacteria,2HWBG@201174|Actinobacteria,4CP6I@84995|Rubrobacteria	84995|Rubrobacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
SRR25158512_k127_4652925_3	479434.Sthe_1882	7.709e-70	244.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4671469_3	136273.GY22_06775	7.296e-112	378.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,1WA48@1268|Micrococcaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158512_k127_4671469_2	526225.Gobs_1853	8.33e-121	400.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4ESDF@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_4671469_1	1463900.JOIX01000010_gene5929	2.548e-161	528.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SRR25158512_k127_4671469_4	105420.BBPO01000062_gene3373	1.111e-41	169.0	2DP3A@1|root,330CA@2|Bacteria,2GPHQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Gly_rich
SRR25158512_k127_4671469_7	370438.PTH_2323	3.758e-09	65.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,254A7@186801|Clostridia,265XF@186807|Peptococcaceae	186801|Clostridia	S	Nitrile hydratase, alpha chain	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4671469_6	1499967.BAYZ01000170_gene5507	3.367e-26	109.0	2BWMX@1|root,2ZIUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4671469_5	266117.Rxyl_0169	6.802e-38	147.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CSRN@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_4671469_0	42256.RradSPS_2412	3.619e-162	522.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CQ0A@84995|Rubrobacteria	84995|Rubrobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158512_k127_4675475_2	266117.Rxyl_2912	4.938e-69	237.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158512_k127_4675475_1	196162.Noca_0389	5.917e-114	386.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4DP12@85009|Propionibacteriales	201174|Actinobacteria	E	amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158512_k127_4675475_0	479434.Sthe_3300	3.881e-204	644.0	COG0665@1|root,COG0665@2|Bacteria,2G86Q@200795|Chloroflexi,27Y37@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158512_k127_4679909_0	2002.JOEQ01000013_gene5376	1.06e-46	168.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EFUP@85012|Streptosporangiales	201174|Actinobacteria	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158512_k127_4679909_2	266117.Rxyl_2609	2.196e-18	86.0	COG0340@1|root,COG0340@2|Bacteria,2HGFP@201174|Actinobacteria,4CQNA@84995|Rubrobacteria	84995|Rubrobacteria	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
SRR25158512_k127_468440_5	42256.RradSPS_2239	7.689e-152	489.0	COG1972@1|root,COG1972@2|Bacteria,2IB7W@201174|Actinobacteria	201174|Actinobacteria	F	Nucleoside transporter	yutK	-	-	ko:K03317,ko:K11535,ko:K16323	-	-	-	-	ko00000,ko02000	2.A.41,2.A.41.1	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
SRR25158512_k127_468440_0	266117.Rxyl_0610	1.857e-198	623.0	COG1015@1|root,COG1015@2|Bacteria,2H5G8@201174|Actinobacteria,4CPW6@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158512_k127_468440_4	266117.Rxyl_0868	5.609e-155	493.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158512_k127_468440_1	266117.Rxyl_0607	2.821e-179	570.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,4CPZB@84995|Rubrobacteria	84995|Rubrobacteria	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158512_k127_468440_6	266117.Rxyl_0606	2.257e-121	392.0	COG0813@1|root,COG0813@2|Bacteria,2GNT6@201174|Actinobacteria,4CU45@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylase superfamily	-	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03784	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158512_k127_468440_3	266117.Rxyl_0605	1.149e-155	502.0	COG2710@1|root,COG2710@2|Bacteria	2|Bacteria	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein	chlN	-	1.3.7.7	ko:K02587,ko:K04038	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro
SRR25158512_k127_468440_2	42256.RradSPS_2245	1.895e-168	541.0	COG2710@1|root,COG2710@2|Bacteria	2|Bacteria	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein	chlB	-	1.3.7.7	ko:K02587,ko:K04038,ko:K04039	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
SRR25158512_k127_4685833_2	279714.FuraDRAFT_3926	9.024e-14	72.0	COG1113@1|root,COG1113@2|Bacteria,1MUPS@1224|Proteobacteria,2VKBM@28216|Betaproteobacteria,2KTUE@206351|Neisseriales	206351|Neisseriales	E	Amino acid permease-associated region	-	-	-	ko:K11735	-	-	-	-	ko00000,ko02000	2.A.3.1.4,2.A.3.1.5	-	-	AA_permease
SRR25158512_k127_4685833_0	42256.RradSPS_2821	4.697e-204	644.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4CPUF@84995|Rubrobacteria	2|Bacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	yhxA	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158512_k127_4685833_1	795666.MW7_1790	1.141e-53	192.0	COG1786@1|root,COG1786@2|Bacteria,1RFUH@1224|Proteobacteria,2VSAS@28216|Betaproteobacteria,1KBB8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
SRR25158512_k127_4695229_0	426355.Mrad2831_3594	2.376e-121	406.0	COG1944@1|root,COG1944@2|Bacteria,1Q7WU@1224|Proteobacteria,2UP1H@28211|Alphaproteobacteria,1JS7M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
SRR25158512_k127_4695229_3	333138.LQ50_14140	1.925e-97	326.0	COG0395@1|root,COG0395@2|Bacteria,1TQG0@1239|Firmicutes,4HD6Q@91061|Bacilli,1ZAVF@1386|Bacillus	91061|Bacilli	P	PFAM binding-protein-dependent transport systems inner membrane component	araQ	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
SRR25158512_k127_4695229_1	333138.LQ50_14135	3.207e-107	355.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,4HB1J@91061|Bacilli,1ZQ7R@1386|Bacillus	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10189	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
SRR25158512_k127_4695229_2	333138.LQ50_14130	1.138e-102	351.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,4HA7Z@91061|Bacilli,1ZF6A@1386|Bacillus	91061|Bacilli	G	ABC transporter substrate-binding protein	lacE	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
SRR25158512_k127_4695229_5	1128421.JAGA01000003_gene3136	2.968e-33	130.0	COG0667@1|root,COG0667@2|Bacteria,2NPI2@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_4701799_0	309801.trd_0273	1.761e-96	340.0	COG0577@1|root,COG0577@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158512_k127_4701799_1	479434.Sthe_1775	5.781e-87	294.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_4701799_2	1121091.AUMP01000033_gene1570	4.837e-18	86.0	28NEU@1|root,2ZBH9@2|Bacteria,1UYBS@1239|Firmicutes,4HFII@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4714107_2	266117.Rxyl_2336	3.946e-69	239.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4CQ21@84995|Rubrobacteria	84995|Rubrobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
SRR25158512_k127_4714107_0	266117.Rxyl_2337	1.805e-162	529.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4CPZU@84995|Rubrobacteria	84995|Rubrobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158512_k127_4714107_1	266117.Rxyl_2338	1.437e-88	300.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
SRR25158512_k127_4714107_3	42256.RradSPS_0622	1.068e-35	143.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
SRR25158512_k127_473253_2	266117.Rxyl_2470	5.74e-29	117.0	COG0619@1|root,COG0619@2|Bacteria,2INV1@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16783,ko:K16785	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
SRR25158512_k127_473253_0	266117.Rxyl_1746	3.428e-201	632.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CP66@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_473253_1	42256.RradSPS_0595	1.291e-131	428.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4CPSU@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_473253_3	266117.Rxyl_2394	8.526e-18	83.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4CPZS@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_4733329_2	479434.Sthe_0007	1.692e-59	207.0	COG0119@1|root,COG0119@2|Bacteria,2G7M0@200795|Chloroflexi,27YV0@189775|Thermomicrobia	189775|Thermomicrobia	E	HMGL-like	-	-	4.1.3.46	ko:K18314	-	-	R10674	RC00502,RC01205	ko00000,ko01000	-	-	-	HMGL-like
SRR25158512_k127_4733329_0	266117.Rxyl_1696	0.0	1128.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CRRW@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158512_k127_4733329_1	266117.Rxyl_1695	1.973e-307	945.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158512_k127_4734544_1	266117.Rxyl_0311	2.404e-77	262.0	COG3408@1|root,COG3408@2|Bacteria,2ICEJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4734544_0	266117.Rxyl_0307	2.964e-118	389.0	COG0584@1|root,COG0584@2|Bacteria,2GM8K@201174|Actinobacteria,4CRQK@84995|Rubrobacteria	84995|Rubrobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158512_k127_4734544_2	1347086.CCBA010000010_gene1761	1.256e-54	198.0	COG3211@1|root,COG3211@2|Bacteria,1V0W5@1239|Firmicutes,4HCDD@91061|Bacilli,1ZDV8@1386|Bacillus	91061|Bacilli	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839,TAT_signal
SRR25158512_k127_4737923_2	42256.RradSPS_2992	5.73e-20	92.0	COG1073@1|root,COG1073@2|Bacteria,2H7CB@201174|Actinobacteria	201174|Actinobacteria	S	COG COG0412 Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis transport and catabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4737923_1	42256.RradSPS_0947	1.995e-69	254.0	COG0642@1|root,COG2202@1|root,COG2461@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	ETR1	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02660,ko:K03406,ko:K07716,ko:K13924	ko02020,ko02025,ko02030,ko04112,map02020,map02025,map02030,map04112	M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SRR25158512_k127_4737923_0	211114.JOEF01000001_gene7349	4.821e-89	314.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4E1GE@85010|Pseudonocardiales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	ybeK	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158512_k127_4737923_3	374847.Kcr_0870	1.948e-05	55.0	COG2324@1|root,arCOG02835@2157|Archaea	2157|Archaea	S	Carotene biosynthesis associated membrane protein	cruF	-	4.2.1.161	ko:K08977	-	-	-	-	ko00000,ko01000	-	-	-	Caroten_synth
SRR25158512_k127_4739635_0	266117.Rxyl_2201	7.091e-192	612.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
SRR25158512_k127_4741212_3	42256.RradSPS_2999	5.145e-43	160.0	COG0071@1|root,COG0071@2|Bacteria,2GVDR@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158512_k127_4741212_2	266117.Rxyl_1171	6.842e-78	264.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4CTBA@84995|Rubrobacteria	84995|Rubrobacteria	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158512_k127_4741212_0	42256.RradSPS_0628	0.0	1227.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4CPSG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158512_k127_4741212_1	266117.Rxyl_0764	8.985e-229	712.0	COG0404@1|root,COG0404@2|Bacteria,2I8C4@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1989,GCV_T,GCV_T_C
SRR25158512_k127_4742918_2	266117.Rxyl_0642	3.609e-70	240.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,2GM8G@201174|Actinobacteria,4CPF4@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,PrmA,TP_methylase
SRR25158512_k127_4742918_0	266117.Rxyl_0643	3.249e-247	777.0	COG1010@1|root,COG2073@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,2GMIR@201174|Actinobacteria,4CQ4T@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.131,3.7.1.12	ko:K13541	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R07772	RC00003,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid,TP_methylase
SRR25158512_k127_4742918_3	266117.Rxyl_0644	5.958e-26	108.0	COG4231@1|root,COG4231@2|Bacteria,2I4BC@201174|Actinobacteria,4CU0K@84995|Rubrobacteria	84995|Rubrobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158512_k127_4742918_1	266117.Rxyl_0645	5.542e-77	265.0	COG2082@1|root,COG2082@2|Bacteria,2GK0B@201174|Actinobacteria,4CQ19@84995|Rubrobacteria	84995|Rubrobacteria	H	Precorrin-8X methylmutase	-	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
SRR25158512_k127_4742918_4	266117.Rxyl_0646	4.566e-09	59.0	COG2138@1|root,COG2138@2|Bacteria,2GS51@201174|Actinobacteria,4CU1K@84995|Rubrobacteria	84995|Rubrobacteria	S	cobalamin (vitamin B12) biosynthesis CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
SRR25158512_k127_4746610_3	266117.Rxyl_0094	1.769e-58	211.0	COG2197@1|root,COG2197@2|Bacteria,2IG2E@201174|Actinobacteria	201174|Actinobacteria	KT	COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_4746610_1	266117.Rxyl_0093	1.008e-147	505.0	COG0784@1|root,COG2202@1|root,COG4585@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CT8E@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HisKA_3,PAS_3,PAS_9,Response_reg
SRR25158512_k127_4746610_0	42256.RradSPS_0174	2.916e-173	564.0	COG3614@1|root,COG4251@1|root,COG3614@2|Bacteria,COG4251@2|Bacteria,2GK25@201174|Actinobacteria,4CQ6R@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase A-like	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA
SRR25158512_k127_4746610_4	266117.Rxyl_1918	8.184e-54	196.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CQK7@84995|Rubrobacteria	84995|Rubrobacteria	K	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158512_k127_4746610_2	479434.Sthe_1008	1.225e-106	355.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4746610_5	1394178.AWOO02000003_gene2627	1.287e-36	145.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4EKDM@85012|Streptosporangiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
SRR25158512_k127_474679_5	266117.Rxyl_2518	9.883e-41	156.0	COG3404@1|root,COG3404@2|Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	-	-	2.1.2.5,4.3.1.4	ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD_C
SRR25158512_k127_474679_1	42256.RradSPS_0632	4.216e-200	638.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
SRR25158512_k127_474679_0	42256.RradSPS_0633	2.001e-213	673.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4CR0T@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158512_k127_474679_3	266117.Rxyl_0769	5.608e-111	364.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4CQZQ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SRR25158512_k127_474679_2	266117.Rxyl_2998	2.43e-198	627.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
SRR25158512_k127_474679_6	1282360.ABAC460_03775	2.444e-36	141.0	COG3791@1|root,COG3791@2|Bacteria,1RH2A@1224|Proteobacteria,2UDAZ@28211|Alphaproteobacteria,2KJ8N@204458|Caulobacterales	204458|Caulobacterales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158512_k127_474679_4	266117.Rxyl_2997	1.573e-54	194.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
SRR25158512_k127_4753239_1	266117.Rxyl_2651	1.208e-92	310.0	COG0555@1|root,COG0555@2|Bacteria,2I4C5@201174|Actinobacteria,4CQ7S@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158512_k127_4753239_0	266117.Rxyl_2650	1.785e-94	317.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria,4CQIG@84995|Rubrobacteria	84995|Rubrobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158512_k127_4753239_2	661478.OP10G_3830	3.285e-31	130.0	COG1956@1|root,COG1956@2|Bacteria	2|Bacteria	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
SRR25158512_k127_4756759_2	266117.Rxyl_1122	3.79e-51	186.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CR10@84995|Rubrobacteria	84995|Rubrobacteria	H	May be involved in the biosynthesis of molybdopterin	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR25158512_k127_4756759_1	266117.Rxyl_1123	4.937e-99	331.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4CQ06@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158512_k127_4756759_0	266117.Rxyl_1124	3.796e-167	531.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CPVK@84995|Rubrobacteria	84995|Rubrobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158512_k127_4764829_0	42256.RradSPS_1415	1.404e-197	620.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CPEF@84995|Rubrobacteria	84995|Rubrobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158512_k127_4764829_1	266117.Rxyl_1411	7.677e-15	79.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158512_k127_4765513_9	435908.IDSA_05150	1.39e-16	83.0	COG1028@1|root,COG1028@2|Bacteria,1QKCK@1224|Proteobacteria,1SJN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_4765513_0	266117.Rxyl_3016	2.239e-205	650.0	COG0769@1|root,COG0769@2|Bacteria,2I2TV@201174|Actinobacteria,4CU6A@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
SRR25158512_k127_4765513_1	266117.Rxyl_3015	5.521e-126	406.0	COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CPRV@84995|Rubrobacteria	84995|Rubrobacteria	S	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
SRR25158512_k127_4765513_3	266117.Rxyl_3013	9.127e-106	357.0	COG1028@1|root,COG1028@2|Bacteria	266117.Rxyl_3013|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4765513_6	235909.GK2920	1.784e-59	213.0	COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,1WE8Z@129337|Geobacillus	91061|Bacilli	M	Acetyltransferase (GNAT) domain	ywnH	GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
SRR25158512_k127_4765513_7	67332.FM21_16340	3.44e-42	168.0	COG0500@1|root,COG2226@2|Bacteria,2GKPQ@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158512_k127_4765513_2	266117.Rxyl_3011	1.33e-108	362.0	COG1028@1|root,COG1028@2|Bacteria,2GK78@201174|Actinobacteria,4CSWM@84995|Rubrobacteria	84995|Rubrobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_4765513_8	1125863.JAFN01000001_gene1708	2.564e-26	115.0	COG1917@1|root,COG1917@2|Bacteria,1MZD8@1224|Proteobacteria,42W0P@68525|delta/epsilon subdivisions,2WRDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_4765513_5	1123242.JH636435_gene2176	9.518e-85	288.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	-	-	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158512_k127_4765513_4	1123242.JH636437_gene6034	3.718e-100	333.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158512_k127_4765924_4	1246995.AFR_15225	1.536e-47	174.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4DCVE@85008|Micromonosporales	201174|Actinobacteria	S	Low temperature requirement A	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158512_k127_4765924_1	266117.Rxyl_0394	5.136e-201	632.0	COG0673@1|root,COG0673@2|Bacteria,2IH5W@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_4765924_2	266117.Rxyl_0395	1.654e-135	451.0	COG1172@1|root,COG1172@2|Bacteria,2GQDN@201174|Actinobacteria,4CT45@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158512_k127_4765924_3	266117.Rxyl_0396	1.092e-133	434.0	COG1172@1|root,COG1172@2|Bacteria,2GQDN@201174|Actinobacteria,4CQEQ@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158512_k127_4765924_0	266117.Rxyl_0397	3.385e-213	671.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4CRYI@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM ABC transporter related	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158512_k127_4770445_5	926550.CLDAP_09410	2.353e-33	144.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2G80F@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158512_k127_4770445_0	391037.Sare_4534	3.476e-178	569.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DDV9@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158512_k127_4770445_1	266117.Rxyl_0387	3.033e-98	338.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria	201174|Actinobacteria	S	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158512_k127_4770445_8	258533.BN977_06088	7.233e-05	49.0	COG2329@1|root,COG2329@2|Bacteria,2I4P2@201174|Actinobacteria,23FCE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158512_k127_4770445_7	324057.Pjdr2_0990	8.463e-07	58.0	2EFXV@1|root,339Q3@2|Bacteria,1VNHT@1239|Firmicutes,4I26M@91061|Bacilli,2705Y@186822|Paenibacillaceae	91061|Bacilli	S	Nitrile hydratase	-	-	-	-	-	-	-	-	-	-	-	-	NHase_alpha
SRR25158512_k127_4770445_3	521011.Mpal_1108	1.66e-66	230.0	arCOG09456@1|root,arCOG09456@2157|Archaea,2XZTI@28890|Euryarchaeota,2NA58@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4770445_2	1120983.KB894571_gene2061	2.646e-77	272.0	COG0510@1|root,COG0510@2|Bacteria,1N77Z@1224|Proteobacteria,2TRW6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Choline kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
SRR25158512_k127_4770445_4	489825.LYNGBM3L_72940	1.896e-60	220.0	COG0500@1|root,COG2226@2|Bacteria,1GHTB@1117|Cyanobacteria,1HGJA@1150|Oscillatoriales	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158512_k127_4770445_6	266117.Rxyl_2461	3.634e-16	82.0	COG1082@1|root,COG1082@2|Bacteria,2HRXW@201174|Actinobacteria,4CU16@84995|Rubrobacteria	84995|Rubrobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158512_k127_4781684_3	42256.RradSPS_0304	1.908e-13	70.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR25158512_k127_4781684_1	42256.RradSPS_0302	2.457e-54	197.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158512_k127_4781684_2	266117.Rxyl_2937	2.109e-52	194.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158512_k127_4781684_0	266117.Rxyl_2938	6.299e-181	574.0	COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CPAE@84995|Rubrobacteria	84995|Rubrobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158512_k127_4783574_1	1144275.COCOR_01842	2.201e-115	380.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_06780	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_4783574_3	37919.EP51_38665	3.349e-104	340.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,4FZ82@85025|Nocardiaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158512_k127_4783574_0	42256.RradSPS_2105	1.228e-179	570.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CPTB@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158512_k127_4783574_6	485913.Krac_10499	4.61e-69	263.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158512_k127_4783574_9	479434.Sthe_1270	2.618e-19	93.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	2|Bacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158512_k127_4783574_10	1384057.CD33_06545	7.753e-19	93.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HF1C@91061|Bacilli,3IWY1@400634|Lysinibacillus	91061|Bacilli	M	peptidase	iap	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3,SLH
SRR25158512_k127_4783574_11	42256.RradSPS_1427	8.303e-19	93.0	COG1426@1|root,COG1426@2|Bacteria,2HNYG@201174|Actinobacteria,4CQ7X@84995|Rubrobacteria	84995|Rubrobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
SRR25158512_k127_4783574_7	644966.Tmar_0739	9.37e-30	133.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
SRR25158512_k127_4783574_2	266117.Rxyl_0478	6.361e-111	368.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CPNM@84995|Rubrobacteria	84995|Rubrobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158512_k127_4783574_5	42256.RradSPS_2260	1.709e-75	259.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4CQ98@84995|Rubrobacteria	84995|Rubrobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158512_k127_4783574_4	266117.Rxyl_0489	2.703e-95	316.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CQI8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158512_k127_4783574_8	266117.Rxyl_0490	1.16e-27	116.0	COG2313@1|root,COG2313@2|Bacteria,2GK19@201174|Actinobacteria,4CPET@84995|Rubrobacteria	84995|Rubrobacteria	Q	Indigoidine synthase A like protein	-	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158512_k127_4791108_2	42256.RradSPS_2509	1.341e-106	353.0	COG0596@1|root,COG0596@2|Bacteria,2I4BT@201174|Actinobacteria,4CR93@84995|Rubrobacteria	84995|Rubrobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158512_k127_4791108_1	1121272.KB903250_gene2802	9.082e-130	422.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DAXK@85008|Micromonosporales	201174|Actinobacteria	EK	Cystathionine beta-synthase	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158512_k127_4791108_0	1382306.JNIM01000001_gene3756	3.653e-151	487.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158512_k127_4791108_3	66897.DJ64_17465	1.092e-05	58.0	COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria	201174|Actinobacteria	H	biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158512_k127_4802417_1	1380356.JNIK01000016_gene3647	1.084e-05	52.0	COG2197@1|root,COG2197@2|Bacteria,2ICWH@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_4802417_0	485913.Krac_6991	3.253e-159	522.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
SRR25158512_k127_4810576_0	266117.Rxyl_2308	3.111e-271	855.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158512_k127_4810576_1	42256.RradSPS_0503	9.398e-65	249.0	COG0520@1|root,COG0520@2|Bacteria,2HP42@201174|Actinobacteria,4CQF7@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
SRR25158512_k127_4823629_5	266117.Rxyl_1250	2.338e-35	137.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676,ko:K06191,ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
SRR25158512_k127_4823629_2	266117.Rxyl_1252	1.58e-55	198.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4CQJU@84995|Rubrobacteria	84995|Rubrobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158512_k127_4823629_1	266117.Rxyl_1253	1.4e-79	268.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	dfa1	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_1,Lactamase_B
SRR25158512_k127_4823629_0	266117.Rxyl_1254	2.683e-113	376.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4CU00@84995|Rubrobacteria	84995|Rubrobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158512_k127_4823629_4	266117.Rxyl_1255	3.499e-50	189.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_N,NTP_transf_3
SRR25158512_k127_4823629_3	266117.Rxyl_1256	2.998e-55	199.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4CU44@84995|Rubrobacteria	84995|Rubrobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158512_k127_4830163_5	266117.Rxyl_1322	1.39e-38	145.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CQCR@84995|Rubrobacteria	84995|Rubrobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158512_k127_4830163_2	266117.Rxyl_1323	2.282e-83	280.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CQA9@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158512_k127_4830163_0	42256.RradSPS_1318	3.944e-177	561.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CP8G@84995|Rubrobacteria	84995|Rubrobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158512_k127_4830163_1	42256.RradSPS_1323	5.553e-112	373.0	COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SRR25158512_k127_4830163_8	1209984.BN978_06648	4.769e-19	94.0	COG0662@1|root,COG0662@2|Bacteria,2IEY0@201174|Actinobacteria,237AC@1762|Mycobacteriaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_4830163_3	926554.KI912633_gene3971	4.509e-57	209.0	COG1917@1|root,COG1917@2|Bacteria,1WN52@1297|Deinococcus-Thermus	2|Bacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_4830163_10	1458357.BG58_15575	1.536e-13	76.0	COG4319@1|root,COG4319@2|Bacteria,1QWVM@1224|Proteobacteria,2WH1S@28216|Betaproteobacteria,1K7YU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_4830163_9	56780.SYN_02900	2.185e-14	81.0	COG5553@1|root,COG5553@2|Bacteria,1NI0U@1224|Proteobacteria,43160@68525|delta/epsilon subdivisions,2WWEA@28221|Deltaproteobacteria,2MS6U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4830163_4	452637.Oter_2282	2.361e-53	193.0	COG2514@1|root,COG2514@2|Bacteria,46SQP@74201|Verrucomicrobia,3K9FN@414999|Opitutae	414999|Opitutae	S	Glyoxalase-like domain	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158512_k127_4832089_1	266117.Rxyl_2482	2.605e-187	593.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CPUT@84995|Rubrobacteria	84995|Rubrobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_4832089_8	649638.Trad_2493	2.546e-95	326.0	COG1215@1|root,COG1215@2|Bacteria,1WIG8@1297|Deinococcus-Thermus	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158512_k127_4832089_0	42256.RradSPS_0427	2.716e-295	912.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4CPEB@84995|Rubrobacteria	84995|Rubrobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158512_k127_4832089_6	1123392.AQWL01000003_gene468	1.402e-111	379.0	COG0625@1|root,COG0625@2|Bacteria,1Q5XX@1224|Proteobacteria,2WBJT@28216|Betaproteobacteria,1KS33@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
SRR25158512_k127_4832089_2	266117.Rxyl_2480	3.306e-172	546.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4CT3Y@84995|Rubrobacteria	84995|Rubrobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158512_k127_4832089_3	42256.RradSPS_0430	1.774e-158	506.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CPUE@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158512_k127_4832089_7	1242864.D187_007090	1.074e-100	334.0	COG0500@1|root,COG0500@2|Bacteria,1QX9N@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158512_k127_4832089_5	1444309.JAQG01000100_gene4691	3.589e-115	389.0	COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,26SPG@186822|Paenibacillaceae	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdB	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158512_k127_4832089_9	1123024.AUII01000013_gene333	6.436e-66	226.0	COG3631@1|root,COG3631@2|Bacteria,2GR1G@201174|Actinobacteria,4EDKX@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_4832089_4	266117.Rxyl_2272	7.339e-120	387.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4CPMD@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158512_k127_4836301_4	1323663.AROI01000023_gene1467	3.594e-45	166.0	COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,1SA1N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	yhaH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF805
SRR25158512_k127_4836301_2	1382306.JNIM01000001_gene1641	4.214e-108	362.0	COG2159@1|root,COG2159@2|Bacteria,2G6EZ@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158512_k127_4836301_3	1382306.JNIM01000001_gene1634	2.65e-102	348.0	COG0174@1|root,COG0174@2|Bacteria,2G62E@200795|Chloroflexi	200795|Chloroflexi	E	Glutamine synthetase N-terminal domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
SRR25158512_k127_4836301_0	2074.JNYD01000015_gene4569	2.612e-203	647.0	COG1113@1|root,COG1113@2|Bacteria,2I3QK@201174|Actinobacteria,4EF67@85010|Pseudonocardiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158512_k127_4836301_1	1032480.MLP_44980	2.959e-127	422.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DTS7@85009|Propionibacteriales	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158512_k127_4839196_4	42256.RradSPS_1989	8.815e-42	156.0	2DMJ8@1|root,32RY9@2|Bacteria,2INPI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4839196_2	1120949.KB903339_gene8032	9.943e-104	343.0	COG1082@1|root,COG1082@2|Bacteria,2HSTT@201174|Actinobacteria,4DFTB@85008|Micromonosporales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158512_k127_4839196_1	1128421.JAGA01000002_gene1466	7.593e-120	398.0	COG0673@1|root,COG0673@2|Bacteria,2NQRC@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158512_k127_4839196_5	1089545.KB913037_gene2428	6.26e-15	83.0	2AYAC@1|root,31QCW@2|Bacteria,2HSG0@201174|Actinobacteria,4EDKN@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4839196_0	66377.JOBH01000008_gene6629	3.7e-147	479.0	COG0141@1|root,COG0141@2|Bacteria,2GNCN@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	-	-	1.1.1.308	ko:K15509	-	-	-	-	ko00000,ko01000	-	-	-	Histidinol_dh
SRR25158512_k127_4839196_3	1304275.C41B8_10675	9.803e-66	235.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158512_k127_4844504_2	246196.MSMEI_4321	2.374e-123	423.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,2366A@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158512_k127_4844504_4	1209984.BN978_02143	6.944e-10	63.0	2BFCX@1|root,32969@2|Bacteria,2HSWS@201174|Actinobacteria,23EBQ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4844504_3	1394178.AWOO02000022_gene7140	2.147e-63	226.0	arCOG11916@1|root,2ZC20@2|Bacteria	2|Bacteria	S	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158512_k127_4844504_0	1157634.KB912988_gene4521	4.313e-226	707.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
SRR25158512_k127_4844504_1	266117.Rxyl_0679	2.767e-125	409.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria,4CQUG@84995|Rubrobacteria	84995|Rubrobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRR25158512_k127_4845307_1	266117.Rxyl_0011	4.053e-120	390.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CP7M@84995|Rubrobacteria	84995|Rubrobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158512_k127_4845307_0	266117.Rxyl_0012	2.896e-153	487.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CPGQ@84995|Rubrobacteria	84995|Rubrobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158512_k127_4845307_6	1121129.KB903374_gene542	0.0008146	43.0	2DD50@1|root,2ZGIJ@2|Bacteria,4P8A2@976|Bacteroidetes,2FZIU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4845307_3	266117.Rxyl_0013	1.396e-76	260.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	nudC_1	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
SRR25158512_k127_4845307_2	42256.RradSPS_0017	5.542e-88	294.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158512_k127_4845307_4	195250.CM001776_gene1740	1.915e-40	166.0	COG1928@1|root,COG1928@2|Bacteria,1G2A9@1117|Cyanobacteria,1GZ3C@1129|Synechococcus	1117|Cyanobacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
SRR25158512_k127_4845307_5	525904.Tter_1860	8.618e-06	52.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158512_k127_4863996_1	1114970.PSF113_1026	4.688e-10	68.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1YNQM@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
SRR25158512_k127_4867522_0	378806.STAUR_3127	4.373e-168	534.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2WJXI@28221|Deltaproteobacteria,2YY6G@29|Myxococcales	28221|Deltaproteobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158512_k127_4867522_5	1394178.AWOO02000024_gene5650	4.935e-09	59.0	COG3227@1|root,COG3227@2|Bacteria,2GMQS@201174|Actinobacteria,4EN3Y@85012|Streptosporangiales	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PepSY,Peptidase_M36
SRR25158512_k127_4867522_1	266117.Rxyl_1097	1.249e-163	527.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CP94@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158512_k127_4867522_2	42256.RradSPS_0773	2.525e-132	436.0	COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4CPXG@84995|Rubrobacteria	84995|Rubrobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158512_k127_4867522_3	66869.JNXG01000003_gene3095	2.676e-74	266.0	COG2746@1|root,COG2746@2|Bacteria,2GNV9@201174|Actinobacteria,41C8C@629295|Streptomyces griseus group	201174|Actinobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
SRR25158512_k127_4867522_4	316274.Haur_2911	5.807e-30	120.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi,37518@32061|Chloroflexia	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
SRR25158512_k127_48727_2	102232.GLO73106DRAFT_00041410	7.14e-30	128.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	FAD_oxidored,FTP,PPC,Peptidase_M4,Peptidase_M4_C,Peptidase_S8,SLH,VCBS
SRR25158512_k127_48727_3	1244869.H261_13728	0.000776	48.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2JUYE@204441|Rhodospirillales	204441|Rhodospirillales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
SRR25158512_k127_48727_0	266117.Rxyl_2329	9.665e-161	510.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4CPJD@84995|Rubrobacteria	84995|Rubrobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158512_k127_48727_1	42256.RradSPS_0479	5.342e-140	447.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CPBA@84995|Rubrobacteria	84995|Rubrobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158512_k127_4878537_5	649638.Trad_0396	2.032e-35	137.0	2C3PP@1|root,2Z954@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4878537_2	649638.Trad_0395	1.005e-148	475.0	COG0115@1|root,COG0115@2|Bacteria,1WIHP@1297|Deinococcus-Thermus	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE_1	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158512_k127_4878537_4	345341.KUTG_08588	1.714e-45	174.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158512_k127_4878537_3	1118054.CAGW01000048_gene1617	2.535e-71	249.0	COG0454@1|root,COG0456@2|Bacteria,1V40T@1239|Firmicutes,4HI2H@91061|Bacilli,26YNM@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4878537_0	266117.Rxyl_0075	6.386e-216	678.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CQ2U@84995|Rubrobacteria	84995|Rubrobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158512_k127_4878537_1	266117.Rxyl_0074	6.266e-160	516.0	COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CP8N@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158512_k127_4893420_0	266117.Rxyl_3111	2.526e-91	310.0	2B8WW@1|root,32276@2|Bacteria,2H6HP@201174|Actinobacteria	201174|Actinobacteria	M	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158512_k127_4893420_1	42256.RradSPS_2992	1.686e-85	309.0	COG1073@1|root,COG1073@2|Bacteria,2H7CB@201174|Actinobacteria	201174|Actinobacteria	S	COG COG0412 Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis transport and catabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4896426_2	42256.RradSPS_1424	3.174e-12	66.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4CPQG@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158512_k127_4896426_0	266117.Rxyl_1420	3.5e-284	880.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CPQX@84995|Rubrobacteria	84995|Rubrobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158512_k127_4896426_1	266117.Rxyl_1421	4.243e-24	110.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158512_k127_4910141_4	313606.M23134_01964	0.0008989	42.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47MCG@768503|Cytophagia	976|Bacteroidetes	IQ	AMP-dependent synthetase and ligase	-	-	6.2.1.44	ko:K00666,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158512_k127_4910141_1	42256.RradSPS_0172	7.279e-77	265.0	COG1216@1|root,COG1216@2|Bacteria,2IIII@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4910141_2	42256.RradSPS_0626	7.921e-73	250.0	COG1309@1|root,COG1309@2|Bacteria,2GJPK@201174|Actinobacteria,4CU34@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158512_k127_4910141_0	42256.RradSPS_0627	4.44e-207	652.0	COG0477@1|root,COG2814@2|Bacteria,2GMBQ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_4910141_3	266117.Rxyl_2359	2.485e-44	165.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4CQZX@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158512_k127_4923044_2	138119.DSY0246	7.752e-30	120.0	COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,24ZI2@186801|Clostridia,26447@186807|Peptococcaceae	186801|Clostridia	C	CoA-ligase	-	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	Ligase_CoA
SRR25158512_k127_4923044_1	43354.JOIJ01000024_gene612	3.49e-120	400.0	COG1055@1|root,COG1055@2|Bacteria,2I46T@201174|Actinobacteria,4EDN9@85010|Pseudonocardiales	201174|Actinobacteria	P	Dicarboxylate carrier protein MatC N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,MatC_N,Na_sulph_symp
SRR25158512_k127_4923044_0	795666.MW7_1789	2.833e-169	540.0	COG1679@1|root,COG1679@2|Bacteria,1NFH4@1224|Proteobacteria,2VISW@28216|Betaproteobacteria,1KHHY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
SRR25158512_k127_4929286_2	266117.Rxyl_1166	9.947e-200	637.0	COG2804@1|root,COG2804@2|Bacteria,2I8C2@201174|Actinobacteria,4CPMS@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158512_k127_4929286_5	42256.RradSPS_1365	1.466e-118	393.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CQ8A@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158512_k127_4929286_8	266117.Rxyl_1360	5.113e-41	155.0	COG0816@1|root,COG0816@2|Bacteria,2HPE8@201174|Actinobacteria,4CQSC@84995|Rubrobacteria	84995|Rubrobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158512_k127_4929286_3	266117.Rxyl_1359	7.299e-143	458.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158512_k127_4929286_0	266117.Rxyl_1359	3.828e-277	862.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CPQA@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158512_k127_4929286_4	42256.RradSPS_1362	4.181e-124	402.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4CQ1F@84995|Rubrobacteria	84995|Rubrobacteria	K	sigma-70 region 3 sigma-70 region 2 sigma-70 region 4 Sigma-70, region 4 type 2	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158512_k127_4929286_1	266117.Rxyl_1354	2.566e-228	717.0	COG0482@1|root,COG0822@1|root,COG0482@2|Bacteria,COG0822@2|Bacteria,2GIUQ@201174|Actinobacteria,4CPQ6@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	NifU_N,tRNA_Me_trans
SRR25158512_k127_4929286_6	266117.Rxyl_1353	6.91e-63	219.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria	201174|Actinobacteria	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158512_k127_4932937_2	306281.AJLK01000201_gene544	1.004e-128	418.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1JK00@1189|Stigonemataceae	1117|Cyanobacteria	M	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158512_k127_4932937_4	329726.AM1_4924	2.652e-66	228.0	COG0295@1|root,COG0295@2|Bacteria,1GDSV@1117|Cyanobacteria	1117|Cyanobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
SRR25158512_k127_4932937_5	526225.Gobs_2273	3.499e-20	96.0	COG1247@1|root,COG1247@2|Bacteria,2IMVR@201174|Actinobacteria,4EWXB@85013|Frankiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4932937_0	1380393.JHVP01000003_gene1104	3.144e-188	609.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	2|Bacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158512_k127_4932937_1	42256.RradSPS_0771	4.839e-159	507.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158512_k127_4932937_3	266117.Rxyl_0869	9.23e-67	229.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CPQJ@84995|Rubrobacteria	84995|Rubrobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158512_k127_4944062_6	266117.Rxyl_0027	2.79e-60	219.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CR9T@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158512_k127_4944062_3	266117.Rxyl_0026	7.151e-142	453.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CQB6@84995|Rubrobacteria	84995|Rubrobacteria	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SRR25158512_k127_4944062_5	266117.Rxyl_0025	4.624e-65	225.0	COG1716@1|root,COG1716@2|Bacteria,2HM1E@201174|Actinobacteria,4CQ7B@84995|Rubrobacteria	84995|Rubrobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SRR25158512_k127_4944062_4	266117.Rxyl_0024	2.038e-141	460.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158512_k127_4944062_0	266117.Rxyl_0023	1.693e-222	695.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CPCV@84995|Rubrobacteria	84995|Rubrobacteria	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
SRR25158512_k127_4944062_2	266117.Rxyl_0022	2.068e-177	573.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CP9M@84995|Rubrobacteria	84995|Rubrobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158512_k127_4944062_1	266117.Rxyl_0021	1.034e-206	664.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158512_k127_4944302_0	266117.Rxyl_0782	2.784e-211	668.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
SRR25158512_k127_4944302_2	266117.Rxyl_0781	3.671e-80	281.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CHAT,PD40
SRR25158512_k127_4944302_1	266117.Rxyl_0777	2.087e-160	510.0	COG2074@1|root,COG2074@2|Bacteria,2H6N5@201174|Actinobacteria	201174|Actinobacteria	G	phosphotransferase activity, carboxyl group as acceptor	-	-	-	ko:K05715	-	-	R02664	RC00002,RC00017	ko00000,ko01000	-	-	-	-
SRR25158512_k127_4955599_0	378806.STAUR_5354	5.13e-279	878.0	COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,42YST@68525|delta/epsilon subdivisions,2WURK@28221|Deltaproteobacteria,2YUH2@29|Myxococcales	28221|Deltaproteobacteria	G	Glucodextranase, domain N	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	CBM_20,Glucodextran_N,Glyco_hydro_15
SRR25158512_k127_4955599_2	266117.Rxyl_3157	1.24e-14	77.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	dpnA	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158512_k127_4955599_1	1120950.KB892746_gene3466	2.471e-62	225.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria,4DVQA@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158512_k127_4956253_3	1267535.KB906767_gene2627	2.377e-67	247.0	COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia	2|Bacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158512_k127_4956253_4	1340493.JNIF01000003_gene4557	0.0007058	43.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y4AC@57723|Acidobacteria	57723|Acidobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
SRR25158512_k127_4956253_1	1052684.PPM_3781	3.977e-119	391.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HB1P@91061|Bacilli,26TV5@186822|Paenibacillaceae	91061|Bacilli	V	LD-carboxypeptidase	yocD	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158512_k127_4956253_0	266117.Rxyl_1051	5.604e-150	481.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CSII@84995|Rubrobacteria	84995|Rubrobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158512_k127_4956253_2	251221.35212847	1.961e-90	306.0	COG0702@1|root,COG0702@2|Bacteria,1G7JG@1117|Cyanobacteria	1117|Cyanobacteria	GM	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SRR25158512_k127_4958255_1	42256.RradSPS_2531	3.719e-55	196.0	COG0841@1|root,COG0841@2|Bacteria,2GMQX@201174|Actinobacteria	201174|Actinobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SRR25158512_k127_4958255_2	42256.RradSPS_2530	1.028e-38	152.0	2C76H@1|root,345XG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4958255_0	1521187.JPIM01000008_gene2112	1.224e-151	494.0	COG2866@1|root,COG2866@2|Bacteria,2G7PS@200795|Chloroflexi,376WU@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158512_k127_4966340_1	42256.RradSPS_2258	1.889e-56	205.0	2CH0A@1|root,30UHJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4966340_4	928724.SacglDRAFT_02945	3.347e-23	105.0	COG1309@1|root,COG1309@2|Bacteria,2I0Y2@201174|Actinobacteria,4E2PJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_4966340_6	358823.DF19_21320	1.102e-05	49.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_4966340_3	483219.LILAB_32145	9.682e-40	162.0	COG1748@1|root,COG1748@2|Bacteria,1PSX2@1224|Proteobacteria,4309H@68525|delta/epsilon subdivisions,2WVCY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
SRR25158512_k127_4966340_2	882086.SacxiDRAFT_3796	5.956e-52	192.0	COG4977@1|root,COG4977@2|Bacteria,2I2KX@201174|Actinobacteria,4E346@85010|Pseudonocardiales	201174|Actinobacteria	K	DJ-1/PfpI family	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158512_k127_4966340_0	1380393.JHVP01000004_gene608	6.85e-76	261.0	COG4977@1|root,COG4977@2|Bacteria,2I2KX@201174|Actinobacteria,4ESZP@85013|Frankiales	201174|Actinobacteria	K	DJ-1/PfpI family	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SRR25158512_k127_4971129_3	68223.JNZY01000002_gene5012	7.271e-09	63.0	2B343@1|root,31VRS@2|Bacteria,2GW49@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4971129_0	266117.Rxyl_2946	1.329e-139	483.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158512_k127_4971129_2	266117.Rxyl_2554	2.764e-61	216.0	COG1051@1|root,COG1051@2|Bacteria,2GZ4B@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158512_k127_4971129_1	266117.Rxyl_2555	4.605e-67	236.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K01992,ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane_2,Abi
SRR25158512_k127_4980144_1	1120973.AQXL01000129_gene2479	2.673e-138	442.0	COG0473@1|root,COG0473@2|Bacteria,1UJAS@1239|Firmicutes,4HCZN@91061|Bacilli,2787J@186823|Alicyclobacillaceae	91061|Bacilli	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
SRR25158512_k127_4980144_3	266117.Rxyl_2652	1.558e-30	121.0	2EAYI@1|root,334ZG@2|Bacteria,2GUJQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_4980144_0	266117.Rxyl_2065	6.495e-156	497.0	COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158512_k127_4980144_2	266117.Rxyl_2064	3.679e-80	271.0	COG2225@1|root,COG2225@2|Bacteria,2GJGP@201174|Actinobacteria,4CQWY@84995|Rubrobacteria	84995|Rubrobacteria	H	malate synthase A	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158512_k127_4995149_6	266117.Rxyl_2912	6.606e-160	511.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158512_k127_4995149_7	266117.Rxyl_2913	4.269e-158	509.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4CQXF@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
SRR25158512_k127_4995149_8	266117.Rxyl_2914	4.697e-145	463.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4CRMW@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158512_k127_4995149_9	266117.Rxyl_2915	5.72e-118	384.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4CQ2P@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158512_k127_4995149_11	469383.Cwoe_2583	1.374e-47	175.0	COG0454@1|root,COG0456@2|Bacteria,2IIPS@201174|Actinobacteria,4CT2B@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158512_k127_4995149_2	42256.RradSPS_0338	4.542e-234	733.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,4CQQ1@84995|Rubrobacteria	84995|Rubrobacteria	E	COG COG0531 Amino acid transporters Amino acid transport and metabolism	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158512_k127_4995149_12	1120958.AULD01000006_gene390	2.36e-39	150.0	COG0589@1|root,COG0589@2|Bacteria,2IIPE@201174|Actinobacteria	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_4995149_3	526225.Gobs_1744	2.872e-212	671.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,4EU7V@85013|Frankiales	201174|Actinobacteria	E	PFAM amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158512_k127_4995149_0	42256.RradSPS_0331	0.0	1011.0	COG3733@1|root,COG3733@2|Bacteria,2GIVJ@201174|Actinobacteria,4CP88@84995|Rubrobacteria	84995|Rubrobacteria	Q	COG COG3733 Cu2 -containing amine oxidase Secondary metabolites biosynthesis transport and catabolism	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
SRR25158512_k127_4995149_5	42256.RradSPS_2967	1.361e-166	538.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4CR27@84995|Rubrobacteria	84995|Rubrobacteria	E	Arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158512_k127_4995149_1	266117.Rxyl_2917	4.231e-257	799.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CPEC@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158512_k127_4995149_4	1123400.KB904802_gene3242	1.824e-202	644.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158512_k127_4995149_10	266117.Rxyl_2906	3.092e-88	295.0	COG0591@1|root,COG0591@2|Bacteria,2GKPW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
SRR25158512_k127_4996801_8	710686.Mycsm_01474	1.636e-15	79.0	COG2151@1|root,COG2151@2|Bacteria,2IAEQ@201174|Actinobacteria,235V1@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158512_k127_4996801_1	42256.RradSPS_1736	1.939e-188	595.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4CPMG@84995|Rubrobacteria	84995|Rubrobacteria	S	Zinc-binding dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_4996801_4	266117.Rxyl_1959	3.417e-126	411.0	COG3191@1|root,COG3191@2|Bacteria,2GJKQ@201174|Actinobacteria	201174|Actinobacteria	EQ	peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
SRR25158512_k127_4996801_3	266117.Rxyl_1960	2.702e-127	413.0	COG1774@1|root,COG1774@2|Bacteria,2HYDT@201174|Actinobacteria	201174|Actinobacteria	S	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
SRR25158512_k127_4996801_2	266117.Rxyl_1961	9.425e-135	442.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CQDV@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
SRR25158512_k127_4996801_6	42256.RradSPS_1741	1.58e-71	247.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CQ6G@84995|Rubrobacteria	84995|Rubrobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158512_k127_4996801_5	266117.Rxyl_1963	2.26e-108	355.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4CQH3@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158512_k127_4996801_0	42256.RradSPS_1743	0.0	1114.0	COG0550@1|root,COG0550@2|Bacteria,2GJU7@201174|Actinobacteria,4CPD0@84995|Rubrobacteria	84995|Rubrobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158512_k127_4996801_7	66692.ABC3557	2.413e-45	171.0	COG0452@1|root,COG0452@2|Bacteria,1VH2Z@1239|Firmicutes,4HQQS@91061|Bacilli,1ZP5W@1386|Bacillus	91061|Bacilli	H	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
SRR25158512_k127_500320_3	404589.Anae109_0703	2.373e-08	60.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158512_k127_500320_0	525904.Tter_2859	5.649e-191	634.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,NB-ARC,Pkinase,TPR_10,TPR_12,Trans_reg_C
SRR25158512_k127_500320_2	882083.SacmaDRAFT_4668	1.057e-71	248.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria,4E6SY@85010|Pseudonocardiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158512_k127_5007742_2	526226.Gbro_4532	5.639e-21	94.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4GAV6@85026|Gordoniaceae	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158512_k127_5007742_3	324602.Caur_3839	2.233e-09	64.0	COG4334@1|root,COG4334@2|Bacteria,2G8RW@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158512_k127_5007742_1	525904.Tter_0218	2.959e-61	219.0	COG0778@1|root,COG0778@2|Bacteria,2NPZS@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158512_k127_5007742_0	1144275.COCOR_01293	2.385e-207	656.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2X3RK@28221|Deltaproteobacteria,2YWXU@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	msbA7	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158512_k127_5013457_0	42256.RradSPS_1211	1.721e-96	323.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4CPJ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
SRR25158512_k127_5013457_1	266117.Rxyl_0704	6.396e-91	311.0	COG4585@1|root,COG4585@2|Bacteria,2IJ1G@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
SRR25158512_k127_5013457_3	266117.Rxyl_0703	1.69e-55	206.0	COG2197@1|root,COG2197@2|Bacteria,2IHF7@201174|Actinobacteria,4CRGW@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_5013457_2	266117.Rxyl_0703	5.045e-56	203.0	COG2197@1|root,COG2197@2|Bacteria,2IHF7@201174|Actinobacteria,4CRGW@84995|Rubrobacteria	84995|Rubrobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158512_k127_5013457_4	1134413.ANNK01000072_gene2892	5.042e-20	98.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus	91061|Bacilli	M	Belongs to the BCCT transporter (TC 2.A.15) family	opuD	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
SRR25158512_k127_5015953_0	1469607.KK073768_gene3377	1.056e-62	228.0	COG1266@1|root,COG1266@2|Bacteria,1G38Y@1117|Cyanobacteria,1HK7G@1161|Nostocales	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158512_k127_5015953_2	266117.Rxyl_0429	1.196e-26	113.0	COG4319@1|root,COG4319@2|Bacteria,2II14@201174|Actinobacteria,4CTN6@84995|Rubrobacteria	84995|Rubrobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158512_k127_5015953_1	1077972.ARGLB_083_00800	2.086e-54	202.0	COG1266@1|root,COG1266@2|Bacteria,2HVFD@201174|Actinobacteria,1WBSF@1268|Micrococcaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158512_k127_5021374_1	42256.RradSPS_0746	5.646e-131	420.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CP6D@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158512_k127_5021374_3	42256.RradSPS_0749	4.539e-105	345.0	COG2738@1|root,COG2738@2|Bacteria,2H5MB@201174|Actinobacteria,4CQEU@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
SRR25158512_k127_5021374_2	42256.RradSPS_0751	8.024e-115	374.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K10914,ko:K21561	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158512_k127_5021374_5	266117.Rxyl_0863	4.375e-93	309.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_5021374_7	266117.Rxyl_0865	2.378e-59	223.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158512_k127_5021374_6	479434.Sthe_3020	3.745e-68	236.0	COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158512_k127_5021374_0	266117.Rxyl_0866	3.859e-136	447.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158512_k127_5040602_1	525904.Tter_2306	5.096e-29	119.0	COG1785@1|root,COG1785@2|Bacteria,2NPNF@2323|unclassified Bacteria	2|Bacteria	P	Alkaline phosphatase homologues	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
SRR25158512_k127_5040602_0	266117.Rxyl_1087	6.052e-269	831.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CS9W@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SRR25158512_k127_5042789_3	266117.Rxyl_0544	6.163e-97	321.0	COG1012@1|root,COG1012@2|Bacteria,2GMNB@201174|Actinobacteria,4CPME@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM aldehyde dehydrogenase	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158512_k127_5042789_1	266117.Rxyl_0545	3.846e-114	374.0	COG3970@1|root,COG3970@2|Bacteria,2GN7V@201174|Actinobacteria	201174|Actinobacteria	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR25158512_k127_5042789_4	44251.PDUR_03060	5.882e-73	256.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,4H9T5@91061|Bacilli,26S96@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158512_k127_5042789_2	1385520.N802_04155	1.123e-109	368.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_5042789_0	1445613.JALM01000074_gene6658	1.03e-172	547.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4DZTN@85010|Pseudonocardiales	201174|Actinobacteria	CE	Tartrate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
SRR25158512_k127_5042789_5	485913.Krac_2309	7.821e-42	161.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158512_k127_5042789_6	797209.ZOD2009_05012	1.22e-22	100.0	COG0604@1|root,arCOG01458@2157|Archaea,2Y39B@28890|Euryarchaeota,23Z1Y@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_5090575_5	266117.Rxyl_0802	1.109e-19	96.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158512_k127_5090575_2	266117.Rxyl_0801	2.008e-63	220.0	COG0736@1|root,COG0736@2|Bacteria,2HPF3@201174|Actinobacteria,4CQTC@84995|Rubrobacteria	84995|Rubrobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158512_k127_5090575_1	266117.Rxyl_0800	5.851e-95	321.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CR9C@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158512_k127_5090575_0	266117.Rxyl_0056	9.136e-154	491.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria,4CPC1@84995|Rubrobacteria	84995|Rubrobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SRR25158512_k127_5090575_4	1123251.ATWM01000003_gene1111	4.311e-26	118.0	2DY8M@1|root,348MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_5090575_3	935848.JAEN01000004_gene1350	1.533e-29	123.0	COG1051@1|root,COG1051@2|Bacteria,1RH1H@1224|Proteobacteria,2U6J2@28211|Alphaproteobacteria,2PX0W@265|Paracoccus	28211|Alphaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158512_k127_513065_0	266117.Rxyl_2959	5.862e-211	662.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SRR25158512_k127_513065_2	42256.RradSPS_0287	2.536e-93	311.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria,4CQW0@84995|Rubrobacteria	84995|Rubrobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158512_k127_513065_1	266117.Rxyl_2957	5.858e-139	445.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CQ40@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
SRR25158512_k127_513065_5	266117.Rxyl_2956	1.696e-06	50.0	COG1290@1|root,COG1290@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
SRR25158512_k127_514404_3	266117.Rxyl_0911	3.955e-31	124.0	COG0760@1|root,COG0760@2|Bacteria,2IGXV@201174|Actinobacteria,4CU3I@84995|Rubrobacteria	84995|Rubrobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	SurA_N_3
SRR25158512_k127_514404_5	252305.OB2597_02987	2.31e-10	64.0	2C2XI@1|root,30D1S@2|Bacteria,1RAWV@1224|Proteobacteria,2U5X3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_514404_6	313589.JNB_17183	4.285e-10	65.0	2C2XI@1|root,30D1S@2|Bacteria,2H3IF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_514404_1	266117.Rxyl_0912	1.734e-118	383.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CPAA@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158512_k127_514404_0	42256.RradSPS_0800	3.569e-236	744.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CPJ2@84995|Rubrobacteria	84995|Rubrobacteria	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158512_k127_514404_4	42256.RradSPS_0801	8.93e-22	97.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
SRR25158512_k127_514404_2	266117.Rxyl_0915	2.204e-62	217.0	COG1507@1|root,COG1507@2|Bacteria	2|Bacteria	FP	Septum formation initiator family protein	ppx2	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K09009	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	DUF501
SRR25158512_k127_515982_1	266117.Rxyl_1383	1.507e-138	444.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria,4CPV9@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158512_k127_515982_6	266117.Rxyl_1382	5.008e-35	136.0	COG0236@1|root,COG0236@2|Bacteria,2HNF1@201174|Actinobacteria,4CQR2@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158512_k127_515982_2	266117.Rxyl_1381	1.211e-121	394.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4CQ36@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158512_k127_515982_5	266117.Rxyl_1380	2.765e-73	249.0	COG0764@1|root,COG0764@2|Bacteria,2GQWT@201174|Actinobacteria	201174|Actinobacteria	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158512_k127_515982_4	42256.RradSPS_1385	4.207e-103	341.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CQ3P@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158512_k127_515982_0	266117.Rxyl_1378	1.169e-150	481.0	COG0332@1|root,COG0332@2|Bacteria,2GJP8@201174|Actinobacteria,4CQ6W@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158512_k127_515982_3	42256.RradSPS_1383	3.057e-120	392.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CQB5@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158512_k127_5208_1	42256.RradSPS_1275	3.469e-260	807.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CPK9@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158512_k127_5208_4	266117.Rxyl_1301	1.925e-85	286.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CQ6T@84995|Rubrobacteria	84995|Rubrobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158512_k127_5208_8	42256.RradSPS_1278	2.306e-20	93.0	COG0291@1|root,COG0291@2|Bacteria,2HPDV@201174|Actinobacteria,4CQRX@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158512_k127_5208_7	266117.Rxyl_1303	1.776e-59	211.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4CQE4@84995|Rubrobacteria	84995|Rubrobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158512_k127_5208_5	266117.Rxyl_1304	2.465e-82	281.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CPWM@84995|Rubrobacteria	84995|Rubrobacteria	J	tRNA rRNA methyltransferase, SpoU	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158512_k127_5208_2	266117.Rxyl_1305	4.103e-182	573.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CPUG@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158512_k127_5208_0	266117.Rxyl_1306	0.0	1105.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CP7V@84995|Rubrobacteria	84995|Rubrobacteria	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158512_k127_5208_6	266117.Rxyl_1307	4.645e-66	231.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
SRR25158512_k127_5208_3	645127.ckrop_1749	2.54e-135	455.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,22JW6@1653|Corynebacteriaceae	201174|Actinobacteria	I	acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3,Lipase_GDSL_2
SRR25158512_k127_534003_0	266117.Rxyl_2544	0.0	1025.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4CRR1@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-binding	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158512_k127_561087_3	266117.Rxyl_1335	4.262e-57	205.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4CU2V@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
SRR25158512_k127_561087_1	266117.Rxyl_1334	6.946e-176	564.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CPTZ@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158512_k127_561087_0	42256.RradSPS_1327	2.224e-179	571.0	COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CPB3@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158512_k127_561087_2	42256.RradSPS_1326	5.324e-96	319.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria	201174|Actinobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158512_k127_563312_6	1440053.JOEI01000001_gene1721	3.737e-17	93.0	28I5U@1|root,2Z890@2|Bacteria,2GKEB@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1996
SRR25158512_k127_563312_3	266117.Rxyl_2213	4.221e-114	373.0	COG1718@1|root,COG1718@2|Bacteria,2GKX1@201174|Actinobacteria,4CQ0B@84995|Rubrobacteria	84995|Rubrobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_563312_5	298655.KI912266_gene5685	2.613e-40	154.0	2CP0Z@1|root,32SI8@2|Bacteria,2IHXV@201174|Actinobacteria,4ET3D@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158512_k127_563312_2	266117.Rxyl_2600	3.859e-123	406.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria,4CSS4@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158512_k127_563312_0	266940.Krad_1014	2.194e-173	557.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria	201174|Actinobacteria	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158512_k127_563312_4	936053.I1CPI0	5.439e-82	284.0	COG1063@1|root,KOG0024@2759|Eukaryota,38I3Q@33154|Opisthokonta,3NZVH@4751|Fungi,1GV4M@112252|Fungi incertae sedis	4751|Fungi	Q	Glucose dehydrogenase C-terminus	-	-	1.1.1.287	ko:K17818	ko00040,ko01100,map00040,map01100	-	R07143,R07144	RC00102	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158512_k127_563312_1	1313172.YM304_41880	2.542e-130	434.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CNHT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158512_k127_564305_0	266117.Rxyl_1024	2.164e-97	325.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3084
SRR25158512_k127_564305_4	266117.Rxyl_1025	4.621e-05	50.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158512_k127_564305_1	266117.Rxyl_1027	1.531e-56	199.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4CQ0S@84995|Rubrobacteria	84995|Rubrobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158512_k127_574265_0	1157943.KB892705_gene2248	2.161e-143	473.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,234WQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
SRR25158512_k127_574265_1	266117.Rxyl_0405	1.738e-127	411.0	COG1131@1|root,COG1131@2|Bacteria,2GJ84@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_574265_2	266117.Rxyl_0406	3.214e-15	79.0	COG0842@1|root,COG0842@2|Bacteria,2GSKI@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158512_k127_574691_0	266117.Rxyl_1411	1e-323	999.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CP7T@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
SRR25158512_k127_574691_4	266117.Rxyl_1412	1.098e-37	143.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158512_k127_574691_3	266117.Rxyl_1413	1.979e-43	161.0	COG0858@1|root,COG0858@2|Bacteria,2HPFC@201174|Actinobacteria,4CQTS@84995|Rubrobacteria	84995|Rubrobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158512_k127_574691_1	266117.Rxyl_1414	1.108e-144	464.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4CPFM@84995|Rubrobacteria	84995|Rubrobacteria	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158512_k127_574691_2	266117.Rxyl_1415	3.056e-44	166.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CPY4@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_N
SRR25158512_k127_575577_2	266117.Rxyl_1579	3.005e-76	259.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4CQ2M@84995|Rubrobacteria	84995|Rubrobacteria	F	Lyase	-	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158512_k127_575577_3	266117.Rxyl_1577	1.217e-48	178.0	COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4CQDS@84995|Rubrobacteria	84995|Rubrobacteria	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158512_k127_575577_0	42256.RradSPS_1066	2.092e-201	632.0	COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria,4CPTA@84995|Rubrobacteria	84995|Rubrobacteria	CH	FAD binding domain	-	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
SRR25158512_k127_575577_1	42256.RradSPS_3073	3.05e-147	476.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CPR9@84995|Rubrobacteria	84995|Rubrobacteria	S	Aldo/keto reductase family	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158512_k127_575577_5	298386.PBPRB1578	7.448e-07	53.0	2DRWY@1|root,33DG4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_575577_4	266117.Rxyl_1003	1.004e-47	173.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria	201174|Actinobacteria	O	belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158512_k127_58391_0	42256.RradSPS_2529	4.213e-156	505.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158512_k127_58391_1	1128421.JAGA01000002_gene557	7.357e-26	109.0	COG2866@1|root,COG2866@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
SRR25158512_k127_588483_3	266117.Rxyl_2087	6.693e-121	398.0	COG0825@1|root,COG0825@2|Bacteria,2I4BQ@201174|Actinobacteria	201174|Actinobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA,Carboxyl_trans
SRR25158512_k127_588483_2	266117.Rxyl_2088	8.02e-129	422.0	COG0777@1|root,COG0777@2|Bacteria,2GNP7@201174|Actinobacteria	201174|Actinobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA,Carboxyl_trans
SRR25158512_k127_588483_4	266117.Rxyl_2089	1.374e-116	381.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4CPX0@84995|Rubrobacteria	84995|Rubrobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158512_k127_588483_0	266117.Rxyl_2090	7.685e-230	718.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CP72@84995|Rubrobacteria	84995|Rubrobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158512_k127_588483_6	748449.Halha_0393	1.219e-40	159.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3WBXQ@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158512_k127_588483_1	42256.RradSPS_1613	1.84e-176	564.0	COG3408@1|root,COG3408@2|Bacteria,2I3UW@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_100,Glyco_hydro_63,Trehalase
SRR25158512_k127_588483_5	221288.JH992901_gene5641	1.485e-86	290.0	COG1225@1|root,COG1278@1|root,COG1225@2|Bacteria,COG1278@2|Bacteria,1GB7U@1117|Cyanobacteria,1JK51@1189|Stigonemataceae	1117|Cyanobacteria	KO	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	AhpC-TSA,CSD
SRR25158512_k127_596014_2	1304275.C41B8_10675	1.504e-96	324.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158512_k127_596014_3	1304275.C41B8_06872	2.502e-64	229.0	COG0388@1|root,COG0388@2|Bacteria,1RA15@1224|Proteobacteria,1S30A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	ramA	-	3.5.1.100	ko:K18540	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158512_k127_596014_1	246196.MSMEI_0500	1.916e-130	423.0	COG0697@1|root,COG0697@2|Bacteria,2HHVP@201174|Actinobacteria,236UP@1762|Mycobacteriaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_596014_0	1449353.JQMQ01000005_gene2463	1.637e-130	424.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria	201174|Actinobacteria	G	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
SRR25158512_k127_611712_2	42256.RradSPS_0438	6.398e-57	209.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	3.4.21.66	ko:K08651,ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158512_k127_611712_3	42256.RradSPS_0435	1.689e-55	199.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158512_k127_611712_0	42256.RradSPS_0437	4.545e-232	750.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158512_k127_611712_1	1120949.KB903295_gene2218	2.862e-116	379.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158512_k127_612495_3	1227360.C176_14057	1.866e-05	48.0	COG0697@1|root,COG0697@2|Bacteria,1TRJZ@1239|Firmicutes,4HDJI@91061|Bacilli,26E98@186818|Planococcaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158512_k127_612495_0	266117.Rxyl_1077	1.029e-129	419.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4CU42@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158512_k127_612495_1	266117.Rxyl_1076	1.175e-78	267.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4CQQI@84995|Rubrobacteria	84995|Rubrobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158512_k127_612495_2	42256.RradSPS_1034	2.116e-13	70.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_23,Methyltransf_25
SRR25158512_k127_616761_3	1283299.AUKG01000001_gene1327	6.385e-10	63.0	COG1651@1|root,COG1651@2|Bacteria,2HP5M@201174|Actinobacteria,4CQHM@84995|Rubrobacteria	84995|Rubrobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158512_k127_616761_2	525904.Tter_1734	3.312e-23	104.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
SRR25158512_k127_616761_0	266117.Rxyl_0979	1.015e-230	721.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CP8S@84995|Rubrobacteria	84995|Rubrobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158512_k127_616761_1	42256.RradSPS_0886	4.674e-40	152.0	COG0822@1|root,COG0822@2|Bacteria,2HNZE@201174|Actinobacteria,4CQ8X@84995|Rubrobacteria	84995|Rubrobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158512_k127_617387_4	525904.Tter_2050	4.982e-20	93.0	COG2390@1|root,COG2390@2|Bacteria,2NQXC@2323|unclassified Bacteria	2|Bacteria	K	Putative sugar-binding domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_28,Sigma70_r4,Sugar-bind
SRR25158512_k127_617387_3	525904.Tter_2482	4.17e-53	192.0	COG0698@1|root,COG0698@2|Bacteria,2NPF4@2323|unclassified Bacteria	2|Bacteria	G	ribose 5-phosphate isomerase B	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158512_k127_617387_2	42256.RradSPS_0057	1.898e-64	229.0	COG4297@1|root,COG4297@2|Bacteria,2H7KC@201174|Actinobacteria,4CTNE@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_617387_0	405948.SACE_3093	6.702e-305	948.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DYDJ@85010|Pseudonocardiales	201174|Actinobacteria	C	Carbon monoxide	xdhA	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158512_k127_617387_1	1050202.KB913024_gene562	1.431e-64	224.0	COG1319@1|root,COG1319@2|Bacteria,2GJF8@201174|Actinobacteria,407Z3@622450|Actinopolysporales	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	xdhB	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158512_k127_619825_7	469383.Cwoe_5741	4.514e-06	51.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
SRR25158512_k127_619825_1	477641.MODMU_0152	1.159e-75	265.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4EV93@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_619825_2	469383.Cwoe_5743	1.529e-57	218.0	COG1277@1|root,COG1277@2|Bacteria,2GR00@201174|Actinobacteria,4CQ7Z@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
SRR25158512_k127_619825_3	266117.Rxyl_2863	1.175e-39	149.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SRR25158512_k127_619825_0	42256.RradSPS_2279	1.074e-87	295.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4CQJ5@84995|Rubrobacteria	84995|Rubrobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158512_k127_619825_6	266117.Rxyl_2865	8.951e-17	87.0	290MR@1|root,2ZNA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SRR25158512_k127_619825_4	649638.Trad_0672	9.142e-37	140.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,GARS_A,Glu_cys_ligase
SRR25158512_k127_626442_1	266117.Rxyl_0676	1.38e-222	711.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CU4U@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM UvrB UvrC protein AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158512_k127_626442_2	42256.RradSPS_2898	9.579e-149	484.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CU3Z@84995|Rubrobacteria	84995|Rubrobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158512_k127_626442_3	42256.RradSPS_2899	4.619e-95	316.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CQ1Q@84995|Rubrobacteria	84995|Rubrobacteria	T	Response regulator receiver	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158512_k127_626442_5	1569209.BBPH01000097_gene1305	1.068e-12	74.0	COG2931@1|root,COG2931@2|Bacteria,1RD83@1224|Proteobacteria,2U93A@28211|Alphaproteobacteria,2PU37@265|Paracoccus	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_626442_0	42256.RradSPS_0611	0.0	1027.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,2GISR@201174|Actinobacteria,4CRMR@84995|Rubrobacteria	84995|Rubrobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR25158512_k127_627166_1	324602.Caur_3034	3.028e-89	300.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi,374W1@32061|Chloroflexia	32061|Chloroflexia	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158512_k127_627166_0	42256.RradSPS_2806	1.552e-102	342.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria	201174|Actinobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158512_k127_634410_8	290399.Arth_1858	9.309e-15	74.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3,NAD_binding_8
SRR25158512_k127_634410_0	404589.Anae109_3618	6.26e-183	581.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
SRR25158512_k127_634410_1	927677.ALVU02000001_gene2236	3.107e-143	472.0	COG0477@1|root,COG0477@2|Bacteria,1G155@1117|Cyanobacteria	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_634410_9	357808.RoseRS_1504	1.483e-12	76.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SRR25158512_k127_634410_11	266117.Rxyl_1922	8.539e-07	55.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158512_k127_634410_3	526225.Gobs_4221	3.261e-70	246.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria,4EV4D@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158512_k127_634410_5	1123261.AXDW01000011_gene587	1.361e-32	133.0	2E083@1|root,32VVX@2|Bacteria,1N26N@1224|Proteobacteria,1T14P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_634410_4	1121377.KB906417_gene3859	2.865e-66	235.0	2950P@1|root,2ZSDF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_634410_2	1454010.JEOE01000034_gene1809	3.261e-70	246.0	2DBV7@1|root,2ZB9P@2|Bacteria,2IGRZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158512_k127_634410_7	1121017.AUFG01000015_gene2677	1.847e-20	100.0	2C5FD@1|root,31C27@2|Bacteria,2IMQG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_634410_10	33876.JNXY01000024_gene4851	7.425e-10	68.0	COG1266@1|root,COG1266@2|Bacteria,2IID1@201174|Actinobacteria,4DID8@85008|Micromonosporales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158512_k127_634410_6	1077972.ARGLB_008_00330	8.989e-27	116.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158512_k127_638041_1	1242864.D187_007328	2.322e-06	53.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158512_k127_638041_0	266117.Rxyl_0576	3.147e-215	679.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4CPAC@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM phenylalanine histidine ammonia-lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158512_k127_64131_0	266117.Rxyl_2012	1.618e-202	640.0	COG1524@1|root,COG1524@2|Bacteria,2HNGC@201174|Actinobacteria,4CPCH@84995|Rubrobacteria	84995|Rubrobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158512_k127_64131_1	1122138.AQUZ01000010_gene5138	1.17e-172	571.0	COG1813@1|root,COG3903@1|root,COG1813@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DTPK@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,HTH_31,TPR_12,Trans_reg_C
SRR25158512_k127_64131_3	1313172.YM304_30910	4.258e-28	123.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
SRR25158512_k127_649471_9	485913.Krac_4976	1.799e-18	98.0	COG4521@1|root,COG4521@2|Bacteria	2|Bacteria	P	taurine ABC transporter	-	-	-	ko:K02051,ko:K15551	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	NMT1,NMT1_2
SRR25158512_k127_649471_5	1394178.AWOO02000006_gene3398	2.734e-95	322.0	COG0600@1|root,COG0600@2|Bacteria,2H2G8@201174|Actinobacteria	201174|Actinobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158512_k127_649471_4	1394178.AWOO02000006_gene3399	1.3e-96	324.0	COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EGTJ@85012|Streptosporangiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158512_k127_649471_8	710696.Intca_0901	2.136e-47	181.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	XK27_00825	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158512_k127_649471_0	266117.Rxyl_1778	1.52e-195	619.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158512_k127_649471_2	266117.Rxyl_2351	2.503e-162	518.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4CQB1@84995|Rubrobacteria	84995|Rubrobacteria	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158512_k127_649471_1	420662.Mpe_A0919	2.518e-172	550.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VM92@28216|Betaproteobacteria,1KJMX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	1.14.13.111	ko:K16968	ko00920,map00920	-	R09513	RC02556	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158512_k127_649471_7	795666.MW7_2344	9.625e-49	183.0	COG5517@1|root,COG5517@2|Bacteria,1RM3X@1224|Proteobacteria,2VTU9@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Aromatic-ring-hydroxylating dioxygenase beta subunit	-	-	1.14.13.111	ko:K16969	ko00920,map00920	-	R09513	RC02556	ko00000,ko00001,ko01000	-	-	-	Ring_hydroxyl_B
SRR25158512_k127_649471_3	266117.Rxyl_2066	3.589e-100	339.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4CQDA@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158512_k127_649471_6	138119.DSY1105	1.215e-73	259.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,1TPTG@1239|Firmicutes,24AMG@186801|Clostridia,26036@186807|Peptococcaceae	186801|Clostridia	EI	PFAM Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158512_k127_650502_1	266117.Rxyl_1406	1.041e-206	646.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CP63@84995|Rubrobacteria	84995|Rubrobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158512_k127_650502_3	42256.RradSPS_1411	2.288e-133	433.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CPEE@84995|Rubrobacteria	84995|Rubrobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158512_k127_650502_2	266117.Rxyl_1404	4.587e-157	505.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CPQ0@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158512_k127_650502_8	42256.RradSPS_1409	5.468e-106	349.0	COG4589@1|root,COG4589@2|Bacteria,2GNWK@201174|Actinobacteria,4CQ05@84995|Rubrobacteria	84995|Rubrobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158512_k127_650502_7	266117.Rxyl_1402	4.441e-108	354.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CPUS@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158512_k127_650502_10	266117.Rxyl_1401	7.687e-84	281.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CQ2J@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158512_k127_650502_6	266117.Rxyl_1400	1.69e-112	368.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CPH9@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158512_k127_650502_9	42256.RradSPS_1405	2.125e-88	299.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CQ46@84995|Rubrobacteria	84995|Rubrobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158512_k127_650502_4	42256.RradSPS_1404	2.345e-129	426.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CQ0Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158512_k127_650502_11	42256.RradSPS_1403	9.962e-74	259.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,4CQ8F@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158512_k127_650502_5	266117.Rxyl_1396	7.961e-118	394.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CQDE@84995|Rubrobacteria	84995|Rubrobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158512_k127_650502_0	266117.Rxyl_1395	4.756e-221	695.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4CPKF@84995|Rubrobacteria	84995|Rubrobacteria	O	magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158512_k127_660455_4	2074.JNYD01000020_gene2704	5.392e-43	165.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_660455_0	525904.Tter_2752	4.691e-129	419.0	COG2423@1|root,COG2423@2|Bacteria,2NPI5@2323|unclassified Bacteria	2|Bacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,1.5.1.25,4.3.1.12	ko:K01750,ko:K18258,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000,ko04147	-	-	-	OCD_Mu_crystall
SRR25158512_k127_660455_2	469383.Cwoe_3466	2.734e-88	305.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_660455_5	266117.Rxyl_0698	9.731e-38	146.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria,4CQE8@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
SRR25158512_k127_660455_1	196162.Noca_4524	1.875e-117	401.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4DSSN@85009|Propionibacteriales	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_660455_3	63737.Npun_F4740	8.577e-72	247.0	2DKWS@1|root,30N64@2|Bacteria,1G5E4@1117|Cyanobacteria,1HS6Q@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR25158512_k127_660455_6	649349.Lbys_0416	0.0004981	44.0	2CMJR@1|root,32SF0@2|Bacteria,4P2TE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_662530_2	1499967.BAYZ01000170_gene5507	6.85e-28	114.0	2BWMX@1|root,2ZIUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_662530_1	266117.Rxyl_0009	9.814e-46	170.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	-
SRR25158512_k127_662530_0	42256.RradSPS_0008	1.679e-183	581.0	COG1432@1|root,COG1432@2|Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158512_k127_669791_7	929712.KI912613_gene2969	1.408e-08	66.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CBM_3,Cadherin-like,Laminin_G_3,SLH
SRR25158512_k127_669791_3	696281.Desru_1186	3.205e-37	148.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,26219@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
SRR25158512_k127_669791_5	56780.SYN_02742	1.601e-33	141.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1R9H3@1224|Proteobacteria,42XHN@68525|delta/epsilon subdivisions,2WT8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_669791_6	500153.JOEK01000001_gene4120	2.787e-12	71.0	COG0662@1|root,COG0662@2|Bacteria,2INXJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_669791_4	1122939.ATUD01000001_gene52	8.808e-36	142.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRR25158512_k127_669791_0	29540.C481_01687	6.209e-89	304.0	COG1874@1|root,arCOG04085@2157|Archaea,2XSU6@28890|Euryarchaeota,23UX4@183963|Halobacteria	183963|Halobacteria	G	COG1874 Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_669791_1	266117.Rxyl_0658	9.677e-82	286.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CSM9@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158512_k127_669791_2	1382304.JNIL01000001_gene2428	4.858e-44	166.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158512_k127_695403_2	266117.Rxyl_3161	6.912e-94	312.0	COG0457@1|root,COG0457@2|Bacteria	266117.Rxyl_3161|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_695403_3	266117.Rxyl_3163	2.046e-66	231.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SRR25158512_k127_695403_4	266117.Rxyl_2715	3.389e-30	123.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4CPDX@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158512_k127_695403_1	266117.Rxyl_3165	3.459e-165	527.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4CPHM@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158512_k127_695403_0	42256.RradSPS_0202	4.217e-244	762.0	COG0749@1|root,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CP7C@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A,DNA_pol_A_exo1
SRR25158512_k127_701302_4	1183438.GKIL_2541	8.648e-57	206.0	COG0390@1|root,COG0390@2|Bacteria,1G1TY@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0014)	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158512_k127_701302_5	266117.Rxyl_0104	4.025e-43	162.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CSRN@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM UspA	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158512_k127_701302_2	5465.ENH82703	4.687e-98	327.0	COG1020@1|root,COG1028@1|root,KOG1178@2759|Eukaryota,KOG1205@2759|Eukaryota,38FV5@33154|Opisthokonta,3NWC5@4751|Fungi,3QNS7@4890|Ascomycota,215P0@147550|Sordariomycetes,1EU3Z@1028384|Glomerellales	4751|Fungi	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,NAD_binding_4,PP-binding,adh_short
SRR25158512_k127_701302_3	266117.Rxyl_2355	5.93e-92	305.0	COG0529@1|root,COG0529@2|Bacteria,2GMUK@201174|Actinobacteria,4CTDY@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158512_k127_701302_0	266117.Rxyl_2349	3.942e-241	749.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	atsG	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158512_k127_701302_1	266117.Rxyl_2350	7.357e-109	359.0	COG4424@1|root,COG4424@2|Bacteria,2GNGY@201174|Actinobacteria	201174|Actinobacteria	S	carbohydrate metabolic process	stf0	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
SRR25158512_k127_709297_0	266117.Rxyl_2016	0.0	1313.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CPHN@84995|Rubrobacteria	84995|Rubrobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158512_k127_714693_1	861299.J421_2982	5.788e-13	69.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Cu_amine_oxidN1,DUF4214
SRR25158512_k127_714693_0	42256.RradSPS_0159	1.525e-180	574.0	COG0323@1|root,COG0323@2|Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c,HATPase_c_3,MutL_C
SRR25158512_k127_717436_0	42256.RradSPS_0506	1.236e-145	463.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CPPG@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158512_k127_717436_1	42256.RradSPS_0505	7.035e-111	364.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4CTRC@84995|Rubrobacteria	84995|Rubrobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158512_k127_717436_2	1173026.Glo7428_0139	4.337e-46	177.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158512_k127_726416_3	1429046.RR21198_4148	1.395e-37	143.0	COG1877@1|root,COG1877@2|Bacteria,2HHMV@201174|Actinobacteria,4FZ8S@85025|Nocardiaceae	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158512_k127_726416_0	471852.Tcur_4794	0.0	1100.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4EGH8@85012|Streptosporangiales	201174|Actinobacteria	G	PFAM glycoside hydrolase family 65 central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158512_k127_726416_1	266117.Rxyl_0733	3.938e-76	261.0	COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CQAP@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158512_k127_726416_2	42256.RradSPS_3040	2.925e-71	244.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CQD2@84995|Rubrobacteria	84995|Rubrobacteria	G	Ribulose-phosphate 3-epimerase	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158512_k127_729575_1	42256.RradSPS_1426	1.377e-249	779.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CPHQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158512_k127_729575_4	266117.Rxyl_1422	4.023e-58	217.0	COG1426@1|root,COG1426@2|Bacteria,2HNYG@201174|Actinobacteria,4CQ7X@84995|Rubrobacteria	84995|Rubrobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
SRR25158512_k127_729575_2	266117.Rxyl_1423	3.752e-181	572.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CPF2@84995|Rubrobacteria	84995|Rubrobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158512_k127_729575_3	266117.Rxyl_1424	1.478e-72	250.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0006282,GO:0008150,GO:0016020,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0044464,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158512_k127_729575_0	266117.Rxyl_1425	2.197e-251	784.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4CS83@84995|Rubrobacteria	84995|Rubrobacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158512_k127_729575_5	266117.Rxyl_1426	1.026e-38	146.0	COG0323@1|root,COG0323@2|Bacteria,2H8CS@201174|Actinobacteria	201174|Actinobacteria	L	histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_3
SRR25158512_k127_729734_2	266117.Rxyl_0802	3.145e-71	243.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CPXV@84995|Rubrobacteria	84995|Rubrobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158512_k127_729734_1	266117.Rxyl_0516	6.733e-80	275.0	COG1692@1|root,COG1692@2|Bacteria,2IG59@201174|Actinobacteria,4CQ4Z@84995|Rubrobacteria	84995|Rubrobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158512_k127_729734_3	266117.Rxyl_0803	7.264e-64	223.0	COG0517@1|root,COG0517@2|Bacteria,2HPZ3@201174|Actinobacteria,4CREF@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158512_k127_729734_0	42256.RradSPS_1835	3.468e-82	291.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRIR@84995|Rubrobacteria	84995|Rubrobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
SRR25158512_k127_737997_13	266117.Rxyl_1653	1.795e-53	188.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158512_k127_737997_9	266117.Rxyl_1653	3.443e-75	259.0	COG3872@1|root,COG3872@2|Bacteria,2IIWY@201174|Actinobacteria,4CPJY@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158512_k127_737997_18	1265490.JHVY01000018_gene293	2.618e-24	103.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	50S ribosomal protein L31	rpmE	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158512_k127_737997_1	266117.Rxyl_1655	2.681e-241	755.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4CQBF@84995|Rubrobacteria	84995|Rubrobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158512_k127_737997_20	42256.RradSPS_1598	7.73e-09	60.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4CP7Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158512_k127_737997_2	266117.Rxyl_1657	2.209e-215	677.0	COG2403@1|root,COG2403@2|Bacteria,2H3G5@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	-
SRR25158512_k127_737997_3	266117.Rxyl_1658	5.768e-149	474.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158512_k127_737997_15	7739.XP_002605796.1	1.002e-41	165.0	2AJ3K@1|root,2RZ64@2759|Eukaryota,3A23K@33154|Opisthokonta,3BQTG@33208|Metazoa,3D7QY@33213|Bilateria	33208|Metazoa	S	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
SRR25158512_k127_737997_0	266117.Rxyl_1659	5.111e-267	833.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CP8V@84995|Rubrobacteria	84995|Rubrobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158512_k127_737997_11	266117.Rxyl_1662	3.99e-59	213.0	COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,4CQFP@84995|Rubrobacteria	84995|Rubrobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SRR25158512_k127_737997_6	42256.RradSPS_1607	2.621e-91	308.0	COG1235@1|root,COG1235@2|Bacteria	2|Bacteria	P	May be involved in the transport of PQQ or its precursor to the periplasm	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158512_k127_737997_10	266117.Rxyl_1664	8.551e-73	263.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	srtA	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158512_k127_737997_16	1521187.JPIM01000188_gene1947	2.184e-37	158.0	29YB7@1|root,30K5H@2|Bacteria,2G83K@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_737997_7	266117.Rxyl_1665	3.564e-84	284.0	COG1633@1|root,COG1633@2|Bacteria,2GQ6Z@201174|Actinobacteria,4CU3W@84995|Rubrobacteria	84995|Rubrobacteria	S	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
SRR25158512_k127_737997_8	42256.RradSPS_1610	1.022e-81	278.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin_2
SRR25158512_k127_737997_5	266117.Rxyl_1667	4.109e-92	305.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4CQ93@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158512_k127_737997_14	266117.Rxyl_1668	7.327e-49	190.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	rskA	GO:0000988,GO:0000989,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010608,GO:0016020,GO:0016989,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158512_k127_737997_4	266117.Rxyl_1671	1.906e-115	380.0	COG4294@1|root,COG4294@2|Bacteria,2GQBS@201174|Actinobacteria,4CTKA@84995|Rubrobacteria	84995|Rubrobacteria	L	UV-endonuclease UvdE	-	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
SRR25158512_k127_737997_12	997346.HMPREF9374_1849	1.641e-53	192.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,27BXC@186824|Thermoactinomycetaceae	91061|Bacilli	S	CoA binding domain	yneT	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158512_k127_737997_17	266117.Rxyl_1674	2.661e-35	139.0	COG2105@1|root,COG2105@2|Bacteria	2|Bacteria	F	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SRR25158512_k127_750849_1	266117.Rxyl_2929	2.327e-131	429.0	COG1503@1|root,COG1503@2|Bacteria,2HQYC@201174|Actinobacteria,4CSQV@84995|Rubrobacteria	84995|Rubrobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_750849_3	266117.Rxyl_2931	3.473e-80	273.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	2_5_RNA_ligase2
SRR25158512_k127_750849_4	42256.RradSPS_0308	9.487e-54	193.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SRR25158512_k127_750849_0	321327.CYA_2477	9.362e-203	657.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1GYE0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158512_k127_750849_2	42256.RradSPS_0305	2.521e-112	371.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CU5T@84995|Rubrobacteria	84995|Rubrobacteria	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158512_k127_750849_5	266117.Rxyl_2936	2.251e-37	144.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR25158512_k127_763776_3	485913.Krac_5994	2.336e-43	163.0	COG5207@1|root,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
SRR25158512_k127_763776_0	42256.RradSPS_1684	3.016e-203	646.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CPQ3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_763776_2	756067.MicvaDRAFT_4968	1.467e-69	240.0	COG3803@1|root,COG3803@2|Bacteria,1G55K@1117|Cyanobacteria,1HAXI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
SRR25158512_k127_763776_1	266117.Rxyl_1053	3.62e-79	269.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	CP_0674	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158512_k127_763776_4	1121377.KB906400_gene1348	3.925e-43	161.0	COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158512_k127_768083_2	266117.Rxyl_2896	2.532e-62	217.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4CPYA@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRR25158512_k127_768083_3	1403819.BATR01000191_gene6582	3.098e-37	145.0	COG2867@1|root,COG2867@2|Bacteria,46WZY@74201|Verrucomicrobia,2IW55@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158512_k127_768083_1	42256.RradSPS_2312	1.495e-77	274.0	COG2267@1|root,COG2267@2|Bacteria,2GYP0@201174|Actinobacteria,4CQF4@84995|Rubrobacteria	84995|Rubrobacteria	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SRR25158512_k127_768083_0	266117.Rxyl_1829	1.032e-95	319.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4CQRB@84995|Rubrobacteria	84995|Rubrobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158512_k127_768083_4	266117.Rxyl_1826	1.436e-16	80.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria,4CQ9I@84995|Rubrobacteria	84995|Rubrobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158512_k127_779452_0	266117.Rxyl_0291	3.56e-136	441.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4CQ3R@84995|Rubrobacteria	84995|Rubrobacteria	P	Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158512_k127_779452_2	374847.Kcr_0870	1.081e-05	55.0	COG2324@1|root,arCOG02835@2157|Archaea	2157|Archaea	S	Carotene biosynthesis associated membrane protein	cruF	-	4.2.1.161	ko:K08977	-	-	-	-	ko00000,ko01000	-	-	-	Caroten_synth
SRR25158512_k127_779452_1	888439.HMPREF9240_01113	6.691e-25	110.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4D40U@85005|Actinomycetales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihB	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158512_k127_7898_2	42256.RradSPS_1999	6.187e-69	235.0	COG0346@1|root,COG0346@2|Bacteria,2IIM8@201174|Actinobacteria,4CQQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158512_k127_7898_5	266117.Rxyl_1162	2.922e-34	139.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K08084,ko:K10926	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	3.A.15.2	-	-	N_methyl
SRR25158512_k127_7898_7	266117.Rxyl_1160	5.428e-27	122.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
SRR25158512_k127_7898_9	42256.RradSPS_0103	1.564e-17	84.0	2E3V5@1|root,32JJK@2|Bacteria,2HPIX@201174|Actinobacteria,4CQWE@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_7898_6	1203568.HMPREF1484_01430	4.49e-27	119.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4FBWD@85020|Dermabacteraceae	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158512_k127_7898_1	266117.Rxyl_2194	6.335e-79	265.0	COG0822@1|root,COG0822@2|Bacteria,2HNZE@201174|Actinobacteria,4CQ8X@84995|Rubrobacteria	84995|Rubrobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158512_k127_7898_0	42256.RradSPS_1993	1.074e-182	576.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CP8W@84995|Rubrobacteria	84995|Rubrobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158512_k127_7898_3	266117.Rxyl_2192	6.75e-55	201.0	2DQBG@1|root,335T7@2|Bacteria	2|Bacteria	S	Selenoprotein B glycine betaine sarcosine D-proline reductase	prdB	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
SRR25158512_k127_792036_4	756499.Desde_2261	4.158e-22	100.0	COG1670@1|root,COG1670@2|Bacteria,1VATK@1239|Firmicutes,24Q0Z@186801|Clostridia,266TX@186807|Peptococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158512_k127_792036_1	266117.Rxyl_1105	1.872e-93	318.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CPKT@84995|Rubrobacteria	84995|Rubrobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158512_k127_792036_0	266117.Rxyl_1108	1.384e-237	754.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CPUU@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158512_k127_792036_5	266117.Rxyl_1110	5.96e-14	72.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
SRR25158512_k127_798531_2	1122611.KB903943_gene1510	3.113e-66	232.0	COG2017@1|root,COG2017@2|Bacteria,2GU0M@201174|Actinobacteria,4EME4@85012|Streptosporangiales	201174|Actinobacteria	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim,DUF4432
SRR25158512_k127_798531_1	1394178.AWOO02000027_gene5271	4.169e-90	305.0	COG1028@1|root,COG1028@2|Bacteria,2GK78@201174|Actinobacteria,4EMRU@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158512_k127_798531_0	1445613.JALM01000003_gene4933	1.121e-217	683.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4E1SG@85010|Pseudonocardiales	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158512_k127_798531_3	1463821.JOGR01000001_gene1569	2.215e-20	93.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4F082@85014|Glycomycetales	201174|Actinobacteria	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,DUF234
SRR25158512_k127_799658_1	1211035.CD30_13980	1.274e-171	551.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HBQK@91061|Bacilli,3J03T@400634|Lysinibacillus	91061|Bacilli	E	Catalyzes the formation of	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158512_k127_799658_8	926550.CLDAP_03750	1.442e-06	59.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_799658_4	1283299.AUKG01000001_gene1392	5.986e-34	138.0	COG0640@1|root,COG0640@2|Bacteria,2IKY0@201174|Actinobacteria,4CQGT@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SRR25158512_k127_799658_0	266117.Rxyl_0593	2.435e-281	883.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPGJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Heavy-metal-associated domain	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158512_k127_799658_3	266117.Rxyl_0590	5.326e-61	218.0	COG3544@1|root,COG3544@2|Bacteria,2GMGR@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
SRR25158512_k127_799658_7	1521187.JPIM01000052_gene3533	1.603e-20	93.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
SRR25158512_k127_799658_2	861299.J421_2256	3.987e-75	269.0	COG0500@1|root,COG2226@2|Bacteria,1ZSM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158512_k127_799658_5	266117.Rxyl_2879	2.986e-26	120.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4CQTZ@84995|Rubrobacteria	84995|Rubrobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158512_k127_799658_6	525904.Tter_2667	1.325e-23	103.0	COG0394@1|root,COG0394@2|Bacteria,2NPGV@2323|unclassified Bacteria	2|Bacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158512_k127_823077_1	485913.Krac_3424	4.811e-31	127.0	COG3239@1|root,COG3239@2|Bacteria,2G80Y@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158512_k127_823077_0	316055.RPE_3904	3.079e-95	330.0	COG2172@1|root,COG2172@2|Bacteria,1RF4I@1224|Proteobacteria,2TY01@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158512_k127_823077_2	1123277.KB893243_gene361	3.028e-15	81.0	COG2133@1|root,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
SRR25158512_k127_827610_3	1341151.ASZU01000016_gene773	2.912e-31	126.0	COG1309@1|root,COG1309@2|Bacteria,1VFYS@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158512_k127_827610_1	1298880.AUEV01000010_gene2812	1.441e-98	343.0	COG0654@1|root,COG0654@2|Bacteria,2GN2W@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158512_k127_827610_0	266117.Rxyl_3202	0.0	1377.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CPVB@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158512_k127_827610_2	882082.SaccyDRAFT_3131	6.356e-57	207.0	2CE4Q@1|root,2Z7WX@2|Bacteria,2H0P6@201174|Actinobacteria,4E993@85010|Pseudonocardiales	201174|Actinobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
SRR25158512_k127_829178_0	1237500.ANBA01000009_gene1223	3.541e-106	352.0	COG0028@1|root,COG0028@2|Bacteria,2GNP2@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158512_k127_829178_3	266117.Rxyl_1009	2.408e-46	173.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
SRR25158512_k127_829178_2	266117.Rxyl_2320	7.537e-59	209.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria,4CQKQ@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158512_k127_829178_1	525904.Tter_0632	4.495e-100	334.0	COG0699@1|root,COG0699@2|Bacteria,2NQN2@2323|unclassified Bacteria	2|Bacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158512_k127_832232_0	266117.Rxyl_0446	1.721e-128	423.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4CQ5Y@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158512_k127_840700_3	266117.Rxyl_0440	2.699e-96	318.0	COG1309@1|root,COG1309@2|Bacteria,2HFWT@201174|Actinobacteria,4CTT8@84995|Rubrobacteria	84995|Rubrobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158512_k127_840700_1	266117.Rxyl_0439	2.233e-116	386.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_840700_2	266117.Rxyl_0438	3.762e-110	360.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158512_k127_840700_0	479432.Sros_1894	1.319e-168	550.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4EFTG@85012|Streptosporangiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158512_k127_852158_3	266117.Rxyl_2552	4.289e-27	111.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	ThiS
SRR25158512_k127_852158_1	266117.Rxyl_2553	9.459e-69	235.0	COG0314@1|root,COG0314@2|Bacteria,2IQ9F@201174|Actinobacteria,4CQW8@84995|Rubrobacteria	84995|Rubrobacteria	H	molybdopterin biosynthesis MoaE	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158512_k127_852158_2	42256.RradSPS_2191	2.994e-27	120.0	COG2149@1|root,COG2149@2|Bacteria,2GX59@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158512_k127_852158_0	1173024.KI912148_gene3290	7.453e-76	261.0	COG2170@1|root,COG2170@2|Bacteria,1G1YE@1117|Cyanobacteria,1JJAH@1189|Stigonemataceae	1117|Cyanobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158512_k127_855385_0	266117.Rxyl_2418	3.469e-177	557.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4CPEP@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158512_k127_855385_1	42256.RradSPS_0555	3.117e-110	365.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	nlhH_1	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,COesterase
SRR25158512_k127_871258_1	42256.RradSPS_2911	3.798e-40	153.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ydgJ	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
SRR25158512_k127_871258_0	42256.RradSPS_2910	2.286e-253	796.0	COG0477@1|root,COG2814@2|Bacteria,2H32P@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_871258_2	266117.Rxyl_0615	8.456e-32	132.0	2942G@1|root,2ZRH8@2|Bacteria,2HDZ5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_871258_3	266117.Rxyl_0616	1.337e-14	79.0	292MX@1|root,2ZQ5T@2|Bacteria,2HCU0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_8803_6	266117.Rxyl_1764	1.49e-23	104.0	COG0477@1|root,COG2814@2|Bacteria,2HRV9@201174|Actinobacteria,4CTZ5@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158512_k127_8803_4	266117.Rxyl_1918	2.032e-58	210.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CQK7@84995|Rubrobacteria	84995|Rubrobacteria	K	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158512_k127_8803_0	266117.Rxyl_1922	0.0	1482.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CPV2@84995|Rubrobacteria	84995|Rubrobacteria	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
SRR25158512_k127_8803_7	694429.Pyrfu_0657	8.317e-12	72.0	COG2405@1|root,arCOG00717@2157|Archaea,2XRYW@28889|Crenarchaeota	28889|Crenarchaeota	V	Domain of unknown function (DUF3368)	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
SRR25158512_k127_8803_3	1219084.AP014508_gene1417	6.699e-76	278.0	COG0405@1|root,COG0405@2|Bacteria,2GCYN@200918|Thermotogae	200918|Thermotogae	M	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158512_k127_8803_2	42256.RradSPS_0364	7.339e-97	326.0	COG3440@1|root,COG3440@2|Bacteria	2|Bacteria	V	regulation of methylation-dependent chromatin silencing	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
SRR25158512_k127_8803_1	485916.Dtox_3104	2.493e-107	361.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,2600W@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158512_k127_881913_2	99598.Cal7507_0562	4.388e-79	274.0	COG0604@1|root,COG0604@2|Bacteria,1G3UU@1117|Cyanobacteria,1HK08@1161|Nostocales	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158512_k127_881913_4	316274.Haur_4037	1.92e-52	206.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia	32061|Chloroflexia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158512_k127_881913_1	266117.Rxyl_1045	5.819e-174	560.0	COG1824@1|root,COG1824@2|Bacteria,2H441@201174|Actinobacteria	201174|Actinobacteria	P	Integral membrane	-	-	-	-	-	-	-	-	-	-	-	-	MgtE
SRR25158512_k127_881913_0	266117.Rxyl_1044	9.904e-204	639.0	COG3273@1|root,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PhoU,TrkA_C
SRR25158512_k127_881913_3	266117.Rxyl_1043	8.736e-72	253.0	COG5650@1|root,COG5650@2|Bacteria,2HYCN@201174|Actinobacteria,4CQKH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158512_k127_887604_0	266117.Rxyl_1316	1.043e-160	509.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CPM6@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158512_k127_887604_3	266117.Rxyl_1317	6.264e-93	310.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CQEG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158512_k127_887604_1	42256.RradSPS_1294	1.791e-116	385.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CPAM@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158512_k127_887604_4	1380347.JNII01000009_gene2274	1.58e-25	108.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158512_k127_887604_2	710421.Mycch_2625	8.258e-105	349.0	COG0657@1|root,COG0657@2|Bacteria,2ICQD@201174|Actinobacteria,237GN@1762|Mycobacteriaceae	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158512_k127_909600_2	479431.Namu_4926	1.335e-58	207.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4EUXK@85013|Frankiales	201174|Actinobacteria	G	Alpha-amylase domain	malL	-	3.2.1.10	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R01718,R01791,R06199	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
SRR25158512_k127_909600_3	42256.RradSPS_2349	1.477e-14	81.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Autoind_bind,GerE
SRR25158512_k127_909600_1	266117.Rxyl_0525	3.233e-59	210.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4CQDC@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158512_k127_909600_0	42256.RradSPS_1075	1.471e-106	351.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CQ8W@84995|Rubrobacteria	84995|Rubrobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158512_k127_911856_2	1121441.AUCX01000001_gene2670	1.23e-72	254.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42SPM@68525|delta/epsilon subdivisions,2WMYY@28221|Deltaproteobacteria,2MAFZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158512_k127_911856_1	266117.Rxyl_2676	2.931e-94	312.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CTQB@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158512_k127_911856_0	656519.Halsa_2143	7.428e-104	352.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WA5V@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158512_k127_914451_2	266117.Rxyl_3111	7.728e-44	169.0	2B8WW@1|root,32276@2|Bacteria,2H6HP@201174|Actinobacteria	201174|Actinobacteria	M	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158512_k127_914451_0	266117.Rxyl_3112	8.035e-178	571.0	COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria	201174|Actinobacteria	V	Negative regulator of	amiA1	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158512_k127_914451_1	266117.Rxyl_3112	5.145e-97	327.0	COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria	201174|Actinobacteria	V	Negative regulator of	amiA1	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
SRR25158512_k127_929812_3	266117.Rxyl_1792	4.602e-25	106.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
SRR25158512_k127_929812_2	675635.Psed_6439	2.643e-51	190.0	COG0596@1|root,COG0596@2|Bacteria,2I320@201174|Actinobacteria,4EFEM@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_929812_4	675635.Psed_6439	1.611e-16	83.0	COG0596@1|root,COG0596@2|Bacteria,2I320@201174|Actinobacteria,4EFEM@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_929812_1	266117.Rxyl_3182	2.536e-118	384.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,4CPVR@84995|Rubrobacteria	84995|Rubrobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,DUF836,Put_DNA-bind_N
SRR25158512_k127_929812_0	266117.Rxyl_3181	5.631e-166	526.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CU2F@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158512_k127_935434_2	1303692.SFUL_534	2.323e-51	184.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria	201174|Actinobacteria	J	elongation factor G	tetM	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158512_k127_935434_1	1297569.MESS2_190022	5.58e-138	444.0	COG3173@1|root,COG3173@2|Bacteria,1R5XN@1224|Proteobacteria,2U3K7@28211|Alphaproteobacteria,43NYC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phosphotransferase enzyme family	kka	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158512_k127_935434_4	266117.Rxyl_0432	9.66e-43	159.0	COG1504@1|root,COG1504@2|Bacteria,2IRTB@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
SRR25158512_k127_935434_0	926550.CLDAP_25170	1.782e-158	506.0	COG0596@1|root,COG0596@2|Bacteria,2GA9B@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158512_k127_935434_5	743719.PaelaDRAFT_3696	7.972e-22	98.0	COG3663@1|root,COG3663@2|Bacteria,1V3X9@1239|Firmicutes,4HHMZ@91061|Bacilli,275TQ@186822|Paenibacillaceae	91061|Bacilli	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158512_k127_935434_3	743719.PaelaDRAFT_3696	3.323e-51	186.0	COG3663@1|root,COG3663@2|Bacteria,1V3X9@1239|Firmicutes,4HHMZ@91061|Bacilli,275TQ@186822|Paenibacillaceae	91061|Bacilli	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158512_k127_938536_0	1445613.JALM01000076_gene128	1.462e-69	250.0	COG0596@1|root,COG0596@2|Bacteria,2GMYM@201174|Actinobacteria,4E938@85010|Pseudonocardiales	201174|Actinobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158512_k127_938536_1	405948.SACE_4576	1.661e-23	104.0	COG0662@1|root,COG0662@2|Bacteria,2IN75@201174|Actinobacteria,4E72Y@85010|Pseudonocardiales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158512_k127_942917_0	266117.Rxyl_0282	1.899e-103	340.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CRGJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158512_k127_942917_1	105420.BBPO01000006_gene2906	9.619e-42	162.0	29SM0@1|root,30DSB@2|Bacteria,2GN13@201174|Actinobacteria,2NEYG@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF4239)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158512_k127_945460_1	266117.Rxyl_2684	5.346e-58	207.0	COG2244@1|root,COG2244@2|Bacteria,2I4II@201174|Actinobacteria,4CTZ7@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158512_k127_945460_0	266117.Rxyl_2686	4.789e-175	559.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158512_k127_945460_2	1463855.JOHV01000086_gene1307	9.853e-07	51.0	COG0451@1|root,COG0451@2|Bacteria,2I2EG@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase dehydratase	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158512_k127_946536_0	266117.Rxyl_1620	7.136e-184	582.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CPCP@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158512_k127_946536_1	266117.Rxyl_1621	1.413e-135	436.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CPGC@84995|Rubrobacteria	84995|Rubrobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158512_k127_949618_2	42256.RradSPS_1969	2.891e-08	54.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4CQG1@84995|Rubrobacteria	84995|Rubrobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158512_k127_949618_0	266117.Rxyl_2180	6.662e-238	745.0	COG1384@1|root,COG1384@2|Bacteria,2GJP1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
SRR25158512_k127_949618_1	42256.RradSPS_1967	2.307e-167	530.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CPPI@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158512_k127_953170_4	1157637.KB892120_gene386	6.234e-17	81.0	COG2334@1|root,COG2334@2|Bacteria,2I2JR@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158512_k127_953170_1	469383.Cwoe_0326	1.807e-144	472.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria	201174|Actinobacteria	S	Low temperature requirement	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158512_k127_953170_0	266117.Rxyl_0753	1.139e-172	550.0	COG1232@1|root,COG1232@2|Bacteria,2HRR6@201174|Actinobacteria,4CTTU@84995|Rubrobacteria	84995|Rubrobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158512_k127_953170_3	42256.RradSPS_2130	1.46e-116	385.0	COG1131@1|root,COG1131@2|Bacteria,2IBZE@201174|Actinobacteria,4CPJZ@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158512_k127_953170_2	266117.Rxyl_0755	1.115e-116	379.0	COG0842@1|root,COG0842@2|Bacteria,2ICWC@201174|Actinobacteria,4CQA1@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158512_k127_959533_1	709986.Deima_1811	1.503e-71	250.0	COG0024@1|root,COG0024@2|Bacteria,1WI2V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158512_k127_959533_2	266117.Rxyl_0700	1.079e-61	216.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	1.1.1.169,3.1.3.25,3.6.1.55	ko:K00077,ko:K01092,ko:K03574	ko00521,ko00562,ko00770,ko01100,ko01110,ko04070,map00521,map00562,map00770,map01100,map01110,map04070	M00119,M00131	R01185,R01186,R01187,R02472	RC00078,RC00726	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	NUDIX
SRR25158512_k127_959533_0	266117.Rxyl_0699	1.834e-85	288.0	COG2129@1|root,COG2129@2|Bacteria,2ICBG@201174|Actinobacteria,4CTTB@84995|Rubrobacteria	84995|Rubrobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158512_k127_959533_3	42256.RradSPS_2170	3.324e-14	72.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K03322,ko:K09944	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Usp
SRR25158512_k127_966409_3	42256.RradSPS_0494	6.196e-124	409.0	COG2244@1|root,COG2244@2|Bacteria,2HRC7@201174|Actinobacteria,4CT9N@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
SRR25158512_k127_966409_2	266117.Rxyl_1238	1.394e-125	410.0	COG0463@1|root,COG0463@2|Bacteria,2GM44@201174|Actinobacteria,4CU1H@84995|Rubrobacteria	84995|Rubrobacteria	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158512_k127_966409_0	1304275.C41B8_01672	1.302e-219	685.0	COG0451@1|root,COG0451@2|Bacteria,1MW8N@1224|Proteobacteria,1RSIY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158512_k127_966409_1	266117.Rxyl_1241	3.467e-185	593.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
SRR25158512_k127_969452_1	266117.Rxyl_3057	1.018e-69	241.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CQ16@84995|Rubrobacteria	84995|Rubrobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158512_k127_969452_3	266117.Rxyl_3055	3.867e-37	149.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158512_k127_969452_0	266117.Rxyl_3054	2.361e-103	348.0	COG1691@1|root,COG1691@2|Bacteria,2IAKU@201174|Actinobacteria	201174|Actinobacteria	C	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158512_k127_969452_4	266117.Rxyl_3053	1.8e-32	129.0	COG0530@1|root,COG0530@2|Bacteria,2IA02@201174|Actinobacteria	201174|Actinobacteria	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158512_k127_970426_0	266117.Rxyl_1998	9.087e-219	685.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4CS1V@84995|Rubrobacteria	84995|Rubrobacteria	H	S-adenosyl-L-homocysteine hydrolase	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158512_k127_970426_1	266117.Rxyl_1999	9.673e-85	287.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria,4CQHH@84995|Rubrobacteria	84995|Rubrobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158512_k127_98451_2	1203554.HMPREF1476_01009	1.107e-10	67.0	COG1403@1|root,COG1403@2|Bacteria,1QE4E@1224|Proteobacteria,2VY9R@28216|Betaproteobacteria,4PR4P@995019|Sutterellaceae	28216|Betaproteobacteria	V	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5,RRXRR
SRR25158512_k127_98451_1	266117.Rxyl_1028	5.297e-95	316.0	COG1802@1|root,COG1802@2|Bacteria,2GKH7@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158512_k127_98451_0	266117.Rxyl_2350	5.993e-108	358.0	COG4424@1|root,COG4424@2|Bacteria,2GNGY@201174|Actinobacteria	201174|Actinobacteria	S	carbohydrate metabolic process	stf0	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681	2.8.2.37	ko:K21014	-	-	-	-	ko00000,ko01000	-	-	-	Sulphotransf
SRR25158512_k127_98451_3	1121372.AULK01000001_gene2554	0.0004742	44.0	COG1887@1|root,COG1887@2|Bacteria,2GYAG@201174|Actinobacteria,4FTBV@85023|Microbacteriaceae	201174|Actinobacteria	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
SRR25158512_k127_993858_1	43759.JNWK01000045_gene3342	6.766e-111	364.0	COG0596@1|root,COG0596@2|Bacteria,2IFCI@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158512_k127_993858_6	882083.SacmaDRAFT_2574	4.49e-10	68.0	2E4RI@1|root,32ZK2@2|Bacteria,2GTNG@201174|Actinobacteria,4E6M9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158512_k127_993858_7	512565.AMIS_78440	2.008e-06	57.0	COG2931@1|root,COG2931@2|Bacteria,2IPR5@201174|Actinobacteria,4DE54@85008|Micromonosporales	201174|Actinobacteria	Q	Hemolysin-type calcium-binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SRR25158512_k127_993858_2	266117.Rxyl_1013	5.441e-80	279.0	COG0517@1|root,COG4747@1|root,COG0517@2|Bacteria,COG4747@2|Bacteria,2GSAR@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
SRR25158512_k127_993858_0	266117.Rxyl_1014	1.894e-190	600.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CPPZ@84995|Rubrobacteria	84995|Rubrobacteria	BQ	histone deacetylase	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158512_k127_993858_3	266117.Rxyl_1015	2.67e-31	126.0	COG2127@1|root,COG2127@2|Bacteria	2|Bacteria	T	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158512_k127_993858_5	42256.RradSPS_0971	2.815e-16	78.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4CQBI@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
## 3249 queries scanned
## Total time (seconds): 5.861004829406738
## Rate: 554.34 q/s