## Mon Dec 15 17:16:47 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158518_bin.6.fa -m mmseqs --itype genome -o SRR25158518_bin.6 --output_dir /data/result/bins/wyx/egg/SRR25158518_bin.6 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158518_k127_1001439_0	324602.Caur_0705	1.56e-132	434.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi,37544@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20,fn3
SRR25158518_k127_1001439_2	235985.BBPN01000053_gene7872	6.332e-08	62.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria,2NISQ@228398|Streptacidiphilus	201174|Actinobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
SRR25158518_k127_1001439_1	234267.Acid_1288	9.959e-95	331.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria	57723|Acidobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158518_k127_1005479_0	28042.GU90_17910	6.288e-93	316.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4DX3U@85010|Pseudonocardiales	201174|Actinobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158518_k127_1005479_2	1121428.DESHY_40060___1	7.785e-33	137.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,262G6@186807|Peptococcaceae	186801|Clostridia	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158518_k127_1005479_1	502025.Hoch_4969	1.869e-41	171.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2YYUB@29|Myxococcales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158518_k127_1005479_3	926569.ANT_15290	1.009e-21	102.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1005479_4	1206732.BAGD01000097_gene4230	8.69e-19	99.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4FVKJ@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158518_k127_1034870_1	383372.Rcas_0301	4.278e-72	256.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SRR25158518_k127_1034870_0	1288826.MSNKSG1_14002	1.486e-73	274.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RPCH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	BQ	COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein	aphA	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158518_k127_1034870_3	446465.Bfae_25500	1.738e-09	70.0	COG0596@1|root,COG0596@2|Bacteria,2GIUK@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158518_k127_1034870_2	408672.NBCG_03380	2.551e-18	89.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4DRU8@85009|Propionibacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158518_k127_1045506_6	118173.KB235910_gene4956	7.138e-19	89.0	2DKWS@1|root,30N64@2|Bacteria,1G5E4@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR25158518_k127_1045506_1	1122132.AQYH01000006_gene3471	2.629e-101	340.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,4BC0Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SRR25158518_k127_1045506_3	743718.Isova_0454	2.328e-56	203.0	COG0800@1|root,COG0800@2|Bacteria,2GNC0@201174|Actinobacteria,4F4D6@85017|Promicromonosporaceae	201174|Actinobacteria	G	KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SRR25158518_k127_1045506_5	867903.ThesuDRAFT_01329	2.693e-20	102.0	COG4309@1|root,COG4309@2|Bacteria,1VHYE@1239|Firmicutes,24RCX@186801|Clostridia	186801|Clostridia	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
SRR25158518_k127_1045506_4	1121924.ATWH01000008_gene748	2.491e-31	131.0	COG2345@1|root,COG2345@2|Bacteria,2IAWJ@201174|Actinobacteria,4FQRZ@85023|Microbacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1045506_2	58123.JOFJ01000012_gene5442	1.829e-78	283.0	COG4243@1|root,COG4243@2|Bacteria,2HG56@201174|Actinobacteria,4EQMU@85012|Streptosporangiales	201174|Actinobacteria	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1045506_0	255470.cbdbA856	1.265e-116	425.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,34D1E@301297|Dehalococcoidia	301297|Dehalococcoidia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158518_k127_1061373_9	1308866.J416_10266	5.902e-26	115.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,470R5@74385|Gracilibacillus	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158518_k127_1061373_7	485913.Krac_11249	1.14e-41	168.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158518_k127_1061373_6	1238182.C882_3167	1.031e-53	210.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,2JQHY@204441|Rhodospirillales	204441|Rhodospirillales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
SRR25158518_k127_1061373_8	1382356.JQMP01000003_gene2497	7.898e-32	143.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,27XW5@189775|Thermomicrobia	189775|Thermomicrobia	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158518_k127_1061373_1	579405.Dd703_0078	1.995e-184	595.0	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,1RN5Y@1236|Gammaproteobacteria,2JCTC@204037|Dickeya	1236|Gammaproteobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	iECO26_1355.ECO26_5036,iPC815.YPO4038	-
SRR25158518_k127_1061373_0	926569.ANT_24910	3.182e-199	633.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158518_k127_1061373_3	347834.RHE_CH03174	4.3e-107	353.0	COG1129@1|root,COG1129@2|Bacteria,1P3ZB@1224|Proteobacteria,2VET1@28211|Alphaproteobacteria,4B7BY@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter, ATP-binding protein	xylG	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
SRR25158518_k127_1061373_2	1297569.MESS2_1480011	4.342e-133	438.0	COG4214@1|root,COG4214@2|Bacteria,1MXXS@1224|Proteobacteria,2TR9B@28211|Alphaproteobacteria,43GUA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	xylH	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
SRR25158518_k127_1061373_4	1208323.B30_08953	5.797e-89	314.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,2TQQW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter substrate-binding protein	xylF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
SRR25158518_k127_1061373_5	1122182.KB903814_gene3524	9.877e-88	304.0	COG1940@1|root,COG1940@2|Bacteria,2GPEI@201174|Actinobacteria,4DAH2@85008|Micromonosporales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158518_k127_1072942_3	262316.MAP_0126	1.199e-22	105.0	COG1846@1|root,COG1846@2|Bacteria,2I3KG@201174|Actinobacteria,238P5@1762|Mycobacteriaceae	201174|Actinobacteria	K	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,MarR
SRR25158518_k127_1072942_2	1267535.KB906767_gene4017	2.813e-26	119.0	COG1393@1|root,COG1393@2|Bacteria,3Y7VT@57723|Acidobacteria	57723|Acidobacteria	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
SRR25158518_k127_1072942_0	192875.XP_004343907.1	6.555e-75	273.0	COG0339@1|root,KOG2089@2759|Eukaryota,38SFI@33154|Opisthokonta	33154|Opisthokonta	O	metalloendopeptidase activity	THOP1	GO:0000209,GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005773,GO:0005794,GO:0005829,GO:0005886,GO:0006109,GO:0006111,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009987,GO:0010675,GO:0010830,GO:0010906,GO:0012505,GO:0016020,GO:0016202,GO:0016567,GO:0016787,GO:0019222,GO:0019538,GO:0023052,GO:0031323,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032446,GO:0033218,GO:0034641,GO:0035556,GO:0036211,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0048634,GO:0048641,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051147,GO:0051153,GO:0051239,GO:0051716,GO:0062012,GO:0065007,GO:0070011,GO:0070012,GO:0070013,GO:0070647,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1901861,GO:1902809,GO:2000026,GO:2001014	3.4.24.15,3.4.24.16,3.4.24.37	ko:K01392,ko:K01393,ko:K01405,ko:K13726	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
SRR25158518_k127_1072942_1	435830.HMPREF0045_00805	2.075e-56	207.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4D33Q@85005|Actinomycetales	201174|Actinobacteria	S	Belongs to the LOG family	fmt2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158518_k127_1088108_0	1445613.JALM01000138_gene3345	1.498e-112	372.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4E1GQ@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
SRR25158518_k127_1088108_1	861299.J421_2228	2.258e-76	268.0	COG0702@1|root,COG0702@2|Bacteria,1ZV6Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRR25158518_k127_1088108_2	1380356.JNIK01000014_gene3482	8.68e-35	143.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158518_k127_1108143_6	1123024.AUII01000015_gene3739	4.893e-17	91.0	COG5646@1|root,COG5646@2|Bacteria,2I3RY@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158518_k127_1108143_0	1128421.JAGA01000003_gene3550	3.757e-120	401.0	COG0277@1|root,COG0277@2|Bacteria,2NQTQ@2323|unclassified Bacteria	2|Bacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158518_k127_1108143_2	928724.SacglDRAFT_01205	7.678e-47	185.0	COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4E3MA@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM redox-sensitive transcriptional activator SoxR	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158518_k127_1108143_5	267608.RSp0476	4.674e-18	98.0	COG3209@1|root,COG4105@1|root,COG3209@2|Bacteria,COG4105@2|Bacteria,1MVV1@1224|Proteobacteria,2VMJI@28216|Betaproteobacteria,1K0C1@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Rhs_assc_core RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PAAR_motif,Peptidase_C39,RHS,RHS_repeat
SRR25158518_k127_1108143_1	1380354.JIAN01000009_gene3833	6.078e-51	196.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,4F0G0@85016|Cellulomonadaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158518_k127_1108143_4	525904.Tter_2060	6.378e-24	117.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR25158518_k127_1108143_7	1386089.N865_11030	1.205e-10	74.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria,4FFZJ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
SRR25158518_k127_1108143_3	479433.Caci_8685	1.206e-26	118.0	COG1309@1|root,COG1309@2|Bacteria,2H2H2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158518_k127_1108676_2	1968.JOEV01000003_gene3296	1.956e-49	196.0	COG4821@1|root,COG4821@2|Bacteria,2GY6Q@201174|Actinobacteria	201174|Actinobacteria	S	protein containing SIS (Sugar isomerase) phosphosugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
SRR25158518_k127_1108676_0	1150399.AQYK01000001_gene896	3.014e-107	371.0	COG0673@1|root,COG0673@2|Bacteria,2IH5W@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158518_k127_1108676_1	926560.KE387023_gene1711	1.605e-86	294.0	COG0274@1|root,COG0274@2|Bacteria,1WMRB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	DeoC/LacD family aldolase	-	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158518_k127_1108676_3	1380391.JIAS01000008_gene5576	1.872e-45	165.0	COG1082@1|root,COG1082@2|Bacteria,1PKSR@1224|Proteobacteria,2U1RX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158518_k127_1112031_0	1370121.AUWS01000033_gene4232	5.646e-137	449.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,234CE@1762|Mycobacteriaceae	201174|Actinobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158518_k127_1112031_3	208444.JNYY01000024_gene410	3.832e-05	54.0	29P24@1|root,30A0A@2|Bacteria,2HAU1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1112031_2	73044.JNXP01000031_gene5486	2.135e-06	52.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158518_k127_1114907_1	1380390.JIAT01000010_gene4484	2.97e-77	267.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	84995|Rubrobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158518_k127_1114907_2	1540221.JQNI01000002_gene1957	3.643e-42	168.0	COG0836@1|root,COG0836@2|Bacteria,1WIIC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158518_k127_1114907_0	1128421.JAGA01000004_gene2629	1.09e-108	385.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgm	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158518_k127_1114907_3	861299.J421_3610	2.447e-26	126.0	COG0662@1|root,COG0662@2|Bacteria,1ZTKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158518_k127_1119465_0	1121017.AUFG01000007_gene1332	1.958e-241	756.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,2H7WY@201174|Actinobacteria,4FFX6@85021|Intrasporangiaceae	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158518_k127_1119465_6	110319.CF8_3965	2.766e-21	102.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158518_k127_1119465_4	1410653.JHVC01000001_gene1634	5.644e-62	233.0	COG0686@1|root,COG0686@2|Bacteria,1UHWP@1239|Firmicutes,24FNG@186801|Clostridia,36V5V@31979|Clostridiaceae	186801|Clostridia	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158518_k127_1119465_3	1159870.KB907784_gene3489	2.698e-112	377.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VP3I@28216|Betaproteobacteria,3T1UW@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158518_k127_1119465_2	1071679.BG57_31120	1.875e-119	399.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2VH1R@28216|Betaproteobacteria,1K89F@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	menC	-	4.2.1.113,4.2.1.171,5.1.1.20	ko:K02549,ko:K19802,ko:K21624	ko00130,ko00330,ko01100,ko01110,map00130,map00330,map01100,map01110	M00116	R04031,R10938,R11625	RC01053,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158518_k127_1119465_5	1454010.JEOE01000020_gene2592	2.914e-53	204.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,4F0RM@85016|Cellulomonadaceae	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158518_k127_1119465_7	1048339.KB913029_gene1613	9.911e-15	85.0	COG3266@1|root,COG3266@2|Bacteria,2I6IN@201174|Actinobacteria	201174|Actinobacteria	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SRR25158518_k127_1119465_1	1126627.BAWE01000006_gene6551	6.889e-230	722.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	sardh	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158518_k127_1128919_0	1382306.JNIM01000001_gene1633	6.574e-61	223.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_1128919_1	1160137.KB907307_gene2376	1.202e-27	121.0	COG1309@1|root,COG1309@2|Bacteria,2GUE9@201174|Actinobacteria,4FYMJ@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158518_k127_1128919_3	1172188.KB911820_gene2449	2.576e-09	62.0	2EIY8@1|root,33CPE@2|Bacteria,2GXKK@201174|Actinobacteria,4FI0G@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1128919_2	1286631.X805_07410	5.414e-27	117.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VKE9@28216|Betaproteobacteria,1KPGV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158518_k127_1148587_1	1121946.AUAX01000036_gene1923	3.214e-12	78.0	2DPD0@1|root,331J4@2|Bacteria,2IFZU@201174|Actinobacteria,4DCU1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1148587_0	103733.JNYO01000006_gene1681	2.059e-34	139.0	COG0454@1|root,COG0456@2|Bacteria,2GY1D@201174|Actinobacteria,4E4N2@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_1151517_1	368407.Memar_0638	6.067e-54	207.0	COG0648@1|root,arCOG01894@2157|Archaea,2XV5I@28890|Euryarchaeota	28890|Euryarchaeota	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158518_k127_1151517_3	1380393.JHVP01000002_gene1562	7.797e-19	94.0	COG3860@1|root,COG3860@2|Bacteria,2IQEK@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20
SRR25158518_k127_1151517_2	574087.Acear_0275	2.993e-34	140.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3WAMR@53433|Halanaerobiales	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158518_k127_1151517_4	380358.XALC_0355	1.291e-18	89.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1X691@135614|Xanthomonadales	135614|Xanthomonadales	S	competence protein	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158518_k127_1152059_9	1122622.ATWJ01000001_gene2572	6.939e-11	69.0	COG3187@1|root,COG3187@2|Bacteria,2I9ND@201174|Actinobacteria	201174|Actinobacteria	O	META domain	hslJ	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
SRR25158518_k127_1152059_1	1386089.N865_05445	6.91e-181	583.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,4FF6H@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158518_k127_1152059_8	1869.MB27_29510	4.411e-12	81.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158518_k127_1152059_0	1042326.AZNV01000033_gene5181	1.102e-276	893.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,4BDH6@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
SRR25158518_k127_1152059_4	408672.NBCG_01487	1.88e-64	245.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria,4DPRP@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158518_k127_1152059_6	1157635.KB892017_gene1714	2.105e-40	171.0	COG1670@1|root,COG1670@2|Bacteria,2II7F@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158518_k127_1152059_2	345341.KUTG_09062	1.109e-81	304.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria,4E29D@85010|Pseudonocardiales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158518_k127_1152059_5	309801.trd_1282	2.097e-62	226.0	COG1834@1|root,COG1834@2|Bacteria,2G7QT@200795|Chloroflexi,27YZU@189775|Thermomicrobia	189775|Thermomicrobia	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
SRR25158518_k127_1152059_7	1283299.AUKG01000001_gene3562	3.795e-35	154.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_1152059_3	926569.ANT_12730	2.789e-80	274.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158518_k127_1156738_6	42256.RradSPS_1227	1.26e-21	108.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
SRR25158518_k127_1156738_5	1254432.SCE1572_22950	9.077e-25	120.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1156738_2	1536770.R50345_03110	1.77e-30	142.0	COG5650@1|root,COG5650@2|Bacteria,1UIQG@1239|Firmicutes,4ISQB@91061|Bacilli,2776M@186822|Paenibacillaceae	91061|Bacilli	S	Pfam:DUF2029	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PIG-U
SRR25158518_k127_1156738_3	1128421.JAGA01000001_gene2079	8.296e-29	137.0	COG4346@1|root,COG4346@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT,PMT_2,PMT_4TMC
SRR25158518_k127_1156738_0	1382356.JQMP01000003_gene1892	2.269e-82	300.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi,27XU5@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158518_k127_1156738_1	1382306.JNIM01000001_gene4122	1.015e-37	159.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
SRR25158518_k127_1156738_7	1996.JOFO01000006_gene451	9.943e-18	98.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4EHU2@85012|Streptosporangiales	201174|Actinobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158518_k127_1156738_4	351607.Acel_1354	2.001e-25	119.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4ESDA@85013|Frankiales	201174|Actinobacteria	M	lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
SRR25158518_k127_1223534_0	309801.trd_0331	3.724e-161	516.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,27XUB@189775|Thermomicrobia	189775|Thermomicrobia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158518_k127_1223534_1	471853.Bcav_2953	1.129e-99	329.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria	201174|Actinobacteria	C	Succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
SRR25158518_k127_1223534_3	350058.Mvan_3618	8.755e-27	128.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,234GG@1762|Mycobacteriaceae	201174|Actinobacteria	GL	Ribonuclease	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
SRR25158518_k127_1223534_2	1499967.BAYZ01000073_gene2029	1.796e-51	193.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158518_k127_1250968_1	446466.Cfla_3327	4.04e-53	197.0	COG3315@1|root,COG3315@2|Bacteria,2GM4W@201174|Actinobacteria	201174|Actinobacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
SRR25158518_k127_1250968_0	526225.Gobs_2170	6.346e-73	258.0	COG1357@1|root,COG1357@2|Bacteria,2GM3W@201174|Actinobacteria,4EU52@85013|Frankiales	201174|Actinobacteria	S	Pentapeptide repeats (8 copies)	yybG	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SRR25158518_k127_1250968_4	1121272.KB903250_gene2962	1.114e-23	104.0	2B8BP@1|root,321KE@2|Bacteria,2H5PU@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158518_k127_1250968_2	105420.BBPO01000016_gene5160	6.442e-29	125.0	COG1309@1|root,COG1309@2|Bacteria,2IQ27@201174|Actinobacteria,2NI4M@228398|Streptacidiphilus	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158518_k127_1250968_3	408672.NBCG_04100	2.396e-26	112.0	2DKWS@1|root,30N64@2|Bacteria,2IQR3@201174|Actinobacteria,4DS31@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
SRR25158518_k127_1254140_1	345341.KUTG_03413	1.232e-49	192.0	COG3336@1|root,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4DXS0@85010|Pseudonocardiales	201174|Actinobacteria	P	Copper resistance	copD	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
SRR25158518_k127_1254140_0	1121381.JNIV01000001_gene2804	5.349e-89	309.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158518_k127_1254140_3	1463917.JODC01000005_gene6775	1.579e-12	78.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulator, TraR DksA family	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158518_k127_1254140_2	1048339.KB913029_gene3548	5.079e-22	96.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,4ESYW@85013|Frankiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158518_k127_1262461_0	367299.JOEE01000001_gene1484	3.583e-45	178.0	COG0308@1|root,COG0308@2|Bacteria,2ID1N@201174|Actinobacteria,4FIRF@85021|Intrasporangiaceae	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1262461_1	1094980.Mpsy_0355	1.728e-09	70.0	COG0308@1|root,arCOG02969@2157|Archaea	2157|Archaea	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158518_k127_1272116_1	1254432.SCE1572_38585	1.34e-132	436.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,43DMV@68525|delta/epsilon subdivisions,2X6DD@28221|Deltaproteobacteria,2Z2W1@29|Myxococcales	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,Glyco_trans_1_4,NAD_binding_8
SRR25158518_k127_1272116_5	479434.Sthe_2665	2.199e-49	201.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
SRR25158518_k127_1272116_6	227882.SAV_767	1.594e-07	65.0	COG0642@1|root,COG2208@1|root,COG2205@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,PAS,PAS_4,PAS_9,SpoIIE,sCache_3_2
SRR25158518_k127_1272116_3	479431.Namu_1451	1.632e-109	369.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4ESAP@85013|Frankiales	201174|Actinobacteria	C	cytochrome P-450	cyp20	-	1.14.14.1	ko:K00493	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	-	R03629,R04121,R05259	RC00046,RC01311	ko00000,ko00001,ko01000	-	-	-	p450
SRR25158518_k127_1272116_4	1504319.GM45_0280	8.761e-91	306.0	COG1738@1|root,COG1738@2|Bacteria,2IFDB@201174|Actinobacteria,3UX0S@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR25158518_k127_1272116_0	1121272.KB903252_gene1184	3.128e-140	476.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4D931@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158518_k127_1272116_2	1121861.KB899920_gene2846	2.074e-117	424.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria,2JRNW@204441|Rhodospirillales	204441|Rhodospirillales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1276306_0	926550.CLDAP_24290	1.703e-27	118.0	COG1615@1|root,COG1615@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158518_k127_128262_2	221288.JH992901_gene4170	2.986e-20	95.0	COG0300@1|root,COG0300@2|Bacteria,1G3JI@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158518_k127_128262_1	292459.STH2498	1.264e-36	154.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRR25158518_k127_128262_4	1172179.AUKV01000009_gene4532	1.431e-15	83.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158518_k127_128262_3	1121430.JMLG01000002_gene1116	1.616e-16	86.0	COG1695@1|root,COG1695@2|Bacteria,1V7D3@1239|Firmicutes,24ME9@186801|Clostridia	186801|Clostridia	K	PFAM Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158518_k127_128262_5	1172179.AUKV01000009_gene4532	1.149e-14	80.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158518_k127_128262_0	1296990.H845_1585	2.961e-86	299.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQV0@28211|Alphaproteobacteria,2JSE2@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158518_k127_1285142_1	521011.Mpal_0243	7.037e-07	61.0	arCOG03622@1|root,arCOG03622@2157|Archaea,2Y29P@28890|Euryarchaeota,2NA5X@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1285142_0	1869.MB27_02390	2.943e-11	76.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria,4DJGS@85008|Micromonosporales	201174|Actinobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PD40
SRR25158518_k127_1289280_3	926550.CLDAP_20900	8.396e-38	147.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158518_k127_1289280_1	316274.Haur_3105	1.324e-131	440.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	scpD	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
SRR25158518_k127_1289280_0	1382306.JNIM01000001_gene1836	1.716e-182	581.0	COG2233@1|root,COG2233@2|Bacteria,2G8VZ@200795|Chloroflexi	200795|Chloroflexi	F	Permease family	-	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
SRR25158518_k127_1289280_2	765420.OSCT_1336	5.901e-102	340.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi,375AJ@32061|Chloroflexia	32061|Chloroflexia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158518_k127_1289280_6	1382306.JNIM01000001_gene3008	9.053e-27	113.0	COG0239@1|root,COG0239@2|Bacteria,2G760@200795|Chloroflexi	200795|Chloroflexi	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158518_k127_1289280_4	670487.Ocepr_1535	1.078e-34	137.0	COG1993@1|root,COG1993@2|Bacteria,1WKB2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
SRR25158518_k127_1289280_5	500153.JOEK01000017_gene3213	3.15e-28	124.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158518_k127_1294683_1	1040987.AZUY01000001_gene2418	3.448e-46	169.0	COG1172@1|root,COG1172@2|Bacteria,1MVKQ@1224|Proteobacteria,2TTT3@28211|Alphaproteobacteria,43JSW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158518_k127_1294683_0	1082933.MEA186_20774	4.177e-90	313.0	COG1172@1|root,COG1172@2|Bacteria,1PRXF@1224|Proteobacteria,2TV5I@28211|Alphaproteobacteria,43RE4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158518_k127_1294683_2	258052.JNYV01000002_gene1729	8.238e-05	49.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,2M20E@2063|Kitasatospora	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox_2
SRR25158518_k127_1343970_0	350054.Mflv_2095	9.931e-237	764.0	COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,2GKVH@201174|Actinobacteria,234TQ@1762|Mycobacteriaceae	201174|Actinobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3
SRR25158518_k127_1349069_0	1128421.JAGA01000002_gene1751	2.204e-115	383.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158518_k127_1349069_1	1384056.N787_03590	6.013e-45	180.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1X48D@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
SRR25158518_k127_1349069_3	1120949.KB903357_gene4802	1.907e-25	121.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4D8Q0@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158518_k127_1349069_2	211165.AJLN01000037_gene1958	8.355e-28	115.0	COG1866@1|root,COG1866@2|Bacteria,1G1KI@1117|Cyanobacteria,1JJE3@1189|Stigonemataceae	1117|Cyanobacteria	C	Phosphoenolpyruvate carboxykinase	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
SRR25158518_k127_1351385_0	1380393.JHVP01000005_gene3676	2.453e-103	361.0	COG2909@1|root,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,4ETWF@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158518_k127_1351385_5	469383.Cwoe_0606	1.243e-13	75.0	COG0599@1|root,COG0599@2|Bacteria,2HUBM@201174|Actinobacteria,4CU1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1351385_1	525897.Dbac_1094	5.425e-102	344.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	beta-lactamase domain protein	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158518_k127_1351385_3	251221.35211248	1.1e-27	115.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158518_k127_1351385_2	1382306.JNIM01000001_gene1417	2.099e-98	333.0	COG0395@1|root,COG0395@2|Bacteria,2G82A@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158518_k127_1351385_4	744872.Spica_0828	2.57e-19	89.0	COG1175@1|root,COG1175@2|Bacteria,2J5SW@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10233	ko02010,map02010	M00201,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158518_k127_1352075_0	485913.Krac_6952	3.547e-64	231.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2G88Z@200795|Chloroflexi	200795|Chloroflexi	O	YHS domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158518_k127_1352075_1	1382306.JNIM01000001_gene2450	1.365e-41	157.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158518_k127_1360250_1	1382306.JNIM01000001_gene857	3.776e-76	269.0	COG1131@1|root,COG1131@2|Bacteria,2G7YX@200795|Chloroflexi	200795|Chloroflexi	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158518_k127_1360250_3	479434.Sthe_0909	6.264e-11	76.0	2BHS8@1|root,33DMI@2|Bacteria,2GBGN@200795|Chloroflexi,27YQG@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
SRR25158518_k127_1360250_2	1289387.AUKW01000005_gene1807	3.671e-46	179.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158518_k127_1360250_0	1288494.EBAPG3_26980	7.577e-77	264.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,371QX@32003|Nitrosomonadales	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158518_k127_1361395_0	381666.H16_A0531	1.551e-97	325.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1K3N3@119060|Burkholderiaceae	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158518_k127_1361395_1	1110697.NCAST_34_04800	2.589e-97	327.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria,4FYDM@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158518_k127_1361395_4	235985.BBPN01000031_gene2131	2.147e-32	145.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,2NEP6@228398|Streptacidiphilus	201174|Actinobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158518_k127_1361395_8	1089551.KE386572_gene1863	1.575e-07	63.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,4BQAH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158518_k127_1361395_6	1033740.CAEW01000016_gene2828	5.312e-17	83.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,26F3I@186818|Planococcaceae	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158518_k127_1361395_5	479434.Sthe_1930	4.028e-20	104.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1361395_3	1089548.KI783301_gene2341	5.56e-59	218.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,3WFH6@539002|Bacillales incertae sedis	91061|Bacilli	KT	helix_turn_helix, Lux Regulon	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158518_k127_1361395_7	1120917.AQXM01000060_gene1100	1.107e-11	77.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,1W7GF@1268|Micrococcaceae	201174|Actinobacteria	T	ANTAR	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158518_k127_1361395_2	330214.NIDE1491	5.741e-64	253.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
SRR25158518_k127_1365525_4	1169161.KB897725_gene1837	5.153e-37	151.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158518_k127_1365525_2	477641.MODMU_1906	2.835e-102	350.0	COG3391@1|root,COG3391@2|Bacteria,2GP11@201174|Actinobacteria,4EX11@85013|Frankiales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
SRR25158518_k127_1365525_3	1380346.JNIH01000050_gene6138	8.336e-91	312.0	COG0500@1|root,COG0500@2|Bacteria,2I3K4@201174|Actinobacteria	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158518_k127_1365525_1	1122611.KB903977_gene2806	5.967e-245	766.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4EGXK@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158518_k127_1365525_6	749414.SBI_02725	3.388e-25	109.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdnG	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
SRR25158518_k127_1365525_0	1385519.N801_00585	8.936e-259	812.0	COG0296@1|root,COG0296@2|Bacteria,2IA2H@201174|Actinobacteria,4FEKD@85021|Intrasporangiaceae	201174|Actinobacteria	G	1,4-alpha-glucan branching enzyme	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158518_k127_1365525_5	1120960.ATXG01000011_gene3561	4.877e-27	125.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria,4FQMK@85023|Microbacteriaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158518_k127_1397757_0	1382356.JQMP01000003_gene1503	1.654e-91	309.0	COG0294@1|root,COG0294@2|Bacteria,2G6A6@200795|Chloroflexi,27XJT@189775|Thermomicrobia	189775|Thermomicrobia	H	Pterin binding enzyme	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158518_k127_1397757_2	477974.Daud_0096	1.199e-27	126.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,262W6@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158518_k127_1397757_1	326427.Cagg_2913	2.712e-62	234.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
SRR25158518_k127_1397757_3	266117.Rxyl_0782	0.0004845	45.0	COG5002@1|root,COG5002@2|Bacteria,2I3V4@201174|Actinobacteria,4CR2M@84995|Rubrobacteria	84995|Rubrobacteria	T	PFAM ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold-4	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
SRR25158518_k127_14076_1	196627.cg3086	4.723e-144	466.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,22JJF@1653|Corynebacteriaceae	201174|Actinobacteria	E	Cystathionine beta-lyases cystathionine	metB	-	2.5.1.48	ko:K01739,ko:K21173	ko00270,ko00450,ko00920,ko01059,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01059,map01100,map01110,map01130,map01230	M00017,M00825	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158518_k127_14076_0	35754.JNYJ01000006_gene5227	5.4e-245	762.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DI0A@85008|Micromonosporales	201174|Actinobacteria	L	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158518_k127_1414990_10	1380347.JNII01000009_gene2090	2.056e-35	145.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4ERV6@85013|Frankiales	201174|Actinobacteria	P	Sulfate permease family	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158518_k127_1414990_3	1206101.AZXC01000008_gene3179	3.813e-99	351.0	COG4325@1|root,COG4325@2|Bacteria,2GWFP@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
SRR25158518_k127_1414990_6	1210908.HSB1_39710	6.649e-51	193.0	COG0385@1|root,arCOG02191@2157|Archaea,2XWY8@28890|Euryarchaeota,23WFA@183963|Halobacteria	183963|Halobacteria	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
SRR25158518_k127_1414990_12	118166.JH976537_gene4082	1.455e-22	106.0	29VND@1|root,30H5P@2|Bacteria,1G6HA@1117|Cyanobacteria,1HFCD@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1414990_14	1463820.JOGW01000009_gene883	1.386e-15	84.0	COG4803@1|root,COG4803@2|Bacteria,2IIN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158518_k127_1414990_19	797304.Natgr_3288	0.0006108	48.0	arCOG09752@1|root,arCOG09752@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1414990_18	1150599.MPHLEI_25516	4.194e-05	54.0	COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,238WY@1762|Mycobacteriaceae	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158518_k127_1414990_8	1380370.JIBA01000003_gene2736	2.129e-40	164.0	2F7A3@1|root,33ZRB@2|Bacteria,2IRS4@201174|Actinobacteria,4FIVD@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158518_k127_1414990_1	314230.DSM3645_15810	4.988e-126	421.0	COG1448@1|root,COG1448@2|Bacteria,2IYDZ@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase	-	-	2.6.1.1	ko:K00813	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158518_k127_1414990_5	926554.KI912622_gene1043	4.679e-87	304.0	COG0714@1|root,COG0714@2|Bacteria,1WJ11@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158518_k127_1414990_9	479434.Sthe_3135	2.365e-39	162.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27Y3Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158518_k127_1414990_17	1382306.JNIM01000001_gene1485	4.026e-06	60.0	COG2807@1|root,COG2807@2|Bacteria,2G7JA@200795|Chloroflexi	200795|Chloroflexi	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
SRR25158518_k127_1414990_2	926569.ANT_16210	1.305e-119	400.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reversible oxidation of malate to oxaloacetate	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158518_k127_1414990_7	1254432.SCE1572_35640	1.371e-40	174.0	COG1807@1|root,COG1807@2|Bacteria,1QZIN@1224|Proteobacteria,435DV@68525|delta/epsilon subdivisions,2WZRC@28221|Deltaproteobacteria,2Z2K8@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1414990_16	1521187.JPIM01000240_gene3267	6.069e-14	83.0	COG0695@1|root,COG0695@2|Bacteria,2G75B@200795|Chloroflexi	200795|Chloroflexi	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158518_k127_1414990_13	1200792.AKYF01000027_gene420	2.17e-22	111.0	COG0438@1|root,COG0438@2|Bacteria,1TT92@1239|Firmicutes,4HCQ5@91061|Bacilli,26ZTA@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158518_k127_1414990_0	1379270.AUXF01000003_gene3892	1.299e-128	430.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158518_k127_1414990_11	1382306.JNIM01000001_gene1452	1.709e-30	138.0	COG0438@1|root,COG0438@2|Bacteria,2G9FM@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158518_k127_1414990_4	1122622.ATWJ01000002_gene771	7.923e-93	330.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4FEHZ@85021|Intrasporangiaceae	201174|Actinobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158518_k127_1415097_4	882086.SacxiDRAFT_3110	6.878e-18	85.0	COG0431@1|root,COG0431@2|Bacteria,2IHWU@201174|Actinobacteria,4E3M9@85010|Pseudonocardiales	201174|Actinobacteria	S	NADPH-dependent FMN reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158518_k127_1415097_3	246196.MSMEI_6704	1.877e-19	95.0	COG1733@1|root,COG1733@2|Bacteria,2IQWP@201174|Actinobacteria,23ESE@1762|Mycobacteriaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158518_k127_1415097_1	1306174.JODP01000009_gene6464	2.247e-59	214.0	COG3022@1|root,COG3022@2|Bacteria,2GJPM@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0246 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
SRR25158518_k127_1415097_2	710696.Intca_0161	3.763e-20	97.0	COG0607@1|root,COG0607@2|Bacteria,2GR81@201174|Actinobacteria,4FHT9@85021|Intrasporangiaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158518_k127_1415097_0	1265502.KB905964_gene1383	2.216e-94	312.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,4AA0K@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158518_k127_1418002_0	357808.RoseRS_4614	3.388e-257	824.0	COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi,37502@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158518_k127_1418002_8	246197.MXAN_1661	1.11e-17	94.0	COG1595@1|root,COG1595@2|Bacteria,1PD6I@1224|Proteobacteria,435EM@68525|delta/epsilon subdivisions,2X98N@28221|Deltaproteobacteria,2Z2MY@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_1418002_5	479433.Caci_1755	2.898e-37	154.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158518_k127_1418002_2	479434.Sthe_1950	3.753e-95	337.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158518_k127_1418002_3	426117.M446_1663	4.027e-80	297.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria,1JTP6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158518_k127_1418002_4	326424.FRAAL0868	6.943e-38	160.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158518_k127_1418002_1	526225.Gobs_2629	1.942e-112	379.0	COG1807@1|root,COG1807@2|Bacteria,2GK3Q@201174|Actinobacteria,4EU3N@85013|Frankiales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158518_k127_1418002_10	644283.Micau_3993	3.711e-07	57.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4D8SS@85008|Micromonosporales	201174|Actinobacteria	V	resistance ABC transporter ATPase subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_1418002_7	1128421.JAGA01000003_gene3395	1.586e-27	117.0	COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_1418002_12	1128421.JAGA01000003_gene3397	0.0001519	53.0	COG0842@1|root,COG0842@2|Bacteria,2NQYW@2323|unclassified Bacteria	2|Bacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158518_k127_1418002_6	1128421.JAGA01000003_gene3397	5.571e-34	140.0	COG0842@1|root,COG0842@2|Bacteria,2NQYW@2323|unclassified Bacteria	2|Bacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158518_k127_1418002_9	316058.RPB_1325	1.599e-10	72.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2TSWT@28211|Alphaproteobacteria,3JT4H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	MA20_03510	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_1419849_1	765420.OSCT_2254	6.934e-43	161.0	COG0348@1|root,COG0348@2|Bacteria,2G8SY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
SRR25158518_k127_1419849_3	765420.OSCT_2255	6.331e-16	82.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
SRR25158518_k127_1419849_0	401526.TcarDRAFT_2520	1.436e-111	377.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4H2A6@909932|Negativicutes	909932|Negativicutes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158518_k127_1419849_5	234267.Acid_1554	2.002e-14	82.0	COG0546@1|root,COG0546@2|Bacteria,3Y5BW@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158518_k127_1419849_4	326427.Cagg_2739	6.625e-15	79.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi,375YA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1419849_2	871968.DESME_15760	2.072e-30	126.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,26287@186807|Peptococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158518_k127_1419849_6	498761.HM1_2406	3.613e-06	56.0	COG3339@1|root,COG3339@2|Bacteria,1VNZM@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158518_k127_1427262_6	1121423.JONT01000003_gene1119	0.0002323	49.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,262C6@186807|Peptococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158518_k127_1427262_2	635013.TherJR_2810	5.707e-35	150.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,2616F@186807|Peptococcaceae	186801|Clostridia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
SRR25158518_k127_1427262_3	1392838.AWNM01000054_gene2974	3.327e-30	134.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	Drug metabolite transporter (DMT) superfamily	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_1427262_0	479434.Sthe_1967	7.852e-146	479.0	COG3004@1|root,COG3004@2|Bacteria,2G7ZG@200795|Chloroflexi	200795|Chloroflexi	P	) H( ) antiporter that extrudes sodium in exchange for external protons	-	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
SRR25158518_k127_1427262_1	1133850.SHJG_2470	1.131e-142	468.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158518_k127_1427262_4	411477.PARMER_01457	2.014e-06	51.0	2DFVK@1|root,2ZTBH@2|Bacteria,4PIGB@976|Bacteroidetes,2G1SY@200643|Bacteroidia,2318W@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1427262_5	1304875.JAFZ01000004_gene476	2.314e-05	47.0	2DD8T@1|root,2ZH33@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1431588_4	649638.Trad_2090	4.936e-31	138.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158518_k127_1431588_5	228410.NE0622	3.558e-28	116.0	COG0662@1|root,COG0662@2|Bacteria,1RFTK@1224|Proteobacteria,2WG1F@28216|Betaproteobacteria,374QB@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158518_k127_1431588_2	861299.J421_5989	7.813e-41	162.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158518_k127_1431588_3	2074.JNYD01000005_gene3171	4.516e-36	143.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria,4E4U9@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158518_k127_1431588_1	1122622.ATWJ01000009_gene3360	1.298e-51	190.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4FF00@85021|Intrasporangiaceae	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158518_k127_1431588_0	324602.Caur_1802	1.787e-64	231.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi,375CE@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158518_k127_1433033_1	1449353.JQMQ01000005_gene5842	2.831e-93	319.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,2NFSK@228398|Streptacidiphilus	201174|Actinobacteria	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
SRR25158518_k127_1433033_0	35754.JNYJ01000012_gene906	4.948e-114	380.0	COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	Crp,ROK
SRR25158518_k127_1433033_2	697281.Mahau_2725	4.951e-44	167.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,42IQ4@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158518_k127_1434731_3	1028800.RG540_CH22920	6.544e-32	130.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,2TQQW@28211|Alphaproteobacteria,4B88V@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC-type xylose transport system, periplasmic component	chvE	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K02058,ko:K10546	ko02010,map02010	M00216,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.5	-	-	Peripla_BP_4
SRR25158518_k127_1434731_0	1128421.JAGA01000001_gene2416	2.522e-222	712.0	COG2160@1|root,COG2160@2|Bacteria	2|Bacteria	G	L-arabinose isomerase activity	araA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060	Arabinose_Iso_C,Arabinose_Isome
SRR25158518_k127_1434731_2	926550.CLDAP_28240	3.494e-84	310.0	COG0235@1|root,COG0235@2|Bacteria,2G63H@200795|Chloroflexi	200795|Chloroflexi	G	Class II Aldolase and Adducin N-terminal domain	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
SRR25158518_k127_1434731_1	316274.Haur_3665	1.772e-103	347.0	COG1609@1|root,COG1609@2|Bacteria,2G6DT@200795|Chloroflexi,376ZH@32061|Chloroflexia	2|Bacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158518_k127_1434731_5	44251.PDUR_10970	3.801e-17	94.0	COG0584@1|root,COG0584@2|Bacteria,1V1B3@1239|Firmicutes,4HGMK@91061|Bacilli,26T3N@186822|Paenibacillaceae	91061|Bacilli	C	-phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158518_k127_1434731_4	5911.EAR83766	3.367e-25	112.0	2CIA6@1|root,2R2BA@2759|Eukaryota,3ZCG9@5878|Ciliophora	5878|Ciliophora	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.13.4	ko:K18764	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	Exo_endo_phos
SRR25158518_k127_1444293_0	1449126.JQKL01000047_gene2724	3.032e-209	665.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,26A0R@186813|unclassified Clostridiales	186801|Clostridia	S	Glutamine synthetase type III N terminal	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
SRR25158518_k127_1450369_1	356851.JOAN01000033_gene1823	4.413e-61	229.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4DB92@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158518_k127_1450369_0	1121367.AQXC01000008_gene426	1.024e-65	238.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,22K17@1653|Corynebacteriaceae	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_1450369_2	383372.Rcas_0237	1.523e-23	111.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,377H1@32061|Chloroflexia	32061|Chloroflexia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158518_k127_1450369_3	1499968.TCA2_0482	8.102e-11	63.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158518_k127_1458026_0	986075.CathTA2_0642	8.175e-119	388.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	aldHT_1	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158518_k127_1458026_2	1124991.MU9_1450	9.235e-12	74.0	COG0454@1|root,COG0456@2|Bacteria,1RI1R@1224|Proteobacteria,1S8CT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_1458026_1	1502724.FF80_02857	3.094e-24	109.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,3N6MC@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158518_k127_1458644_1	765420.OSCT_0827	5.787e-34	133.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,375GF@32061|Chloroflexia	32061|Chloroflexia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SRR25158518_k127_1458644_2	1232410.KI421424_gene1852	2.67e-29	121.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,43SPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	YbaB/EbfC DNA-binding family	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158518_k127_1458644_0	479434.Sthe_1931	3.198e-87	310.0	COG2812@1|root,COG3266@1|root,COG2812@2|Bacteria,COG3266@2|Bacteria,2G5PK@200795|Chloroflexi,27XHA@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158518_k127_1458748_0	420246.GTNG_2709	7.042e-109	365.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1WEHU@129337|Geobacillus	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158518_k127_1458748_1	1521187.JPIM01000060_gene2908	8.129e-80	301.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,3754V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158518_k127_1458748_2	525904.Tter_1356	7.576e-64	234.0	COG1193@1|root,COG1193@2|Bacteria,2NNS1@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158518_k127_1462732_0	1380390.JIAT01000009_gene1863	1.444e-45	176.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CU2Q@84995|Rubrobacteria	84995|Rubrobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_146452_1	479434.Sthe_3420	1.946e-117	395.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,27XZA@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158518_k127_146452_2	525904.Tter_1226	3.083e-117	414.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158518_k127_146452_4	1463820.JOGW01000019_gene2521	3.966e-39	162.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_146452_5	1288494.EBAPG3_1130	5.053e-37	158.0	COG3540@1|root,COG3540@2|Bacteria,1PI5V@1224|Proteobacteria,2W6S3@28216|Betaproteobacteria,374GH@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
SRR25158518_k127_146452_0	1122182.KB903833_gene5401	2.235e-122	434.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158518_k127_146452_3	1382306.JNIM01000001_gene3578	1.863e-54	196.0	COG2141@1|root,COG2141@2|Bacteria,2G6CZ@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_1481283_13	479434.Sthe_0777	1.681e-16	83.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,27XT6@189775|Thermomicrobia	189775|Thermomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
SRR25158518_k127_1481283_1	525904.Tter_0214	1.072e-136	457.0	COG0624@1|root,COG0624@2|Bacteria,2NQM8@2323|unclassified Bacteria	2|Bacteria	E	Peptidase dimerisation domain	dapE	-	3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158518_k127_1481283_5	525904.Tter_1028	2.21e-72	257.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314,ko:K02316,ko:K17680	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032	-	-	-	DnaB_C,Toprim_2,Toprim_N,zf-CHC2
SRR25158518_k127_1481283_8	221359.RS9916_27124	4.202e-47	174.0	COG0221@1|root,COG0221@2|Bacteria,1G1Q3@1117|Cyanobacteria,1GZGC@1129|Synechococcus	1117|Cyanobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SRR25158518_k127_1481283_12	1307759.JOMJ01000003_gene1460	8.239e-22	107.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2MCME@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158518_k127_1481283_0	1458427.BAWN01000018_gene1140	6.416e-199	637.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria,4ACES@80864|Comamonadaceae	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158518_k127_1481283_9	1122611.KB903946_gene719	4.203e-45	188.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158518_k127_1481283_11	485913.Krac_10292	4.535e-31	133.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158518_k127_1481283_10	1122222.AXWR01000024_gene31	6.157e-34	141.0	COG4112@1|root,COG4112@2|Bacteria,1WMU8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158518_k127_1481283_4	479434.Sthe_1855	1.032e-79	284.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia	189775|Thermomicrobia	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158518_k127_1481283_3	926569.ANT_29010	3.398e-95	321.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158518_k127_1481283_6	326427.Cagg_0842	7.503e-71	256.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
SRR25158518_k127_1481283_2	292459.STH1476	8.754e-121	406.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158518_k127_1481283_7	243233.MCA2841	2.272e-49	193.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1XE4B@135618|Methylococcales	135618|Methylococcales	L	PFAM DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158518_k127_1481283_15	765420.OSCT_2726	1.001e-05	55.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi,375VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1481283_14	935863.AWZR01000002_gene1117	3.298e-11	64.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1X3EQ@135614|Xanthomonadales	135614|Xanthomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SRR25158518_k127_1519936_4	1379270.AUXF01000006_gene105	1.31e-21	105.0	COG0289@1|root,COG0289@2|Bacteria,1ZTHH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SRR25158518_k127_1519936_0	379066.GAU_1792	2.938e-78	276.0	COG0329@1|root,COG0329@2|Bacteria,1ZSM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158518_k127_1519936_3	1089550.ATTH01000001_gene1398	7.271e-62	230.0	COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,1FJ1Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Tetrahydrodipicolinate N-succinyltransferase N-terminal	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
SRR25158518_k127_1519936_2	272630.MexAM1_META1p3654	1.235e-70	262.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TUK2@28211|Alphaproteobacteria,1JS1B@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158518_k127_1519936_1	42256.RradSPS_1697	7.167e-73	256.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158518_k127_1525705_1	1068980.ARVW01000001_gene6633	2.041e-28	131.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4DZ4E@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158518_k127_1525705_2	575540.Isop_1232	1.102e-26	119.0	COG3613@1|root,COG3613@2|Bacteria,2J1JH@203682|Planctomycetes	203682|Planctomycetes	F	Nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
SRR25158518_k127_1525705_0	1095767.CAHD01000025_gene1719	2.553e-33	137.0	COG4702@1|root,COG4702@2|Bacteria,2IFGG@201174|Actinobacteria,4F17G@85016|Cellulomonadaceae	201174|Actinobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158518_k127_1551935_0	316274.Haur_0326	3.182e-111	369.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,374U8@32061|Chloroflexia	32061|Chloroflexia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158518_k127_1551935_2	1122611.KB904007_gene7842	2.101e-44	170.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4EG3J@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420,ko:K10914,ko:K21561,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158518_k127_1551935_1	319795.Dgeo_2136	7.773e-73	260.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1WIX8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM competence damage-inducible protein CinA N-terminal domain	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158518_k127_1563756_0	1120948.KB903245_gene3428	7.086e-07	59.0	COG0500@1|root,COG2226@2|Bacteria,2GQ64@201174|Actinobacteria,4DYD6@85010|Pseudonocardiales	201174|Actinobacteria	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158518_k127_1565908_0	1125863.JAFN01000001_gene559	4.108e-214	698.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158518_k127_1565908_8	1440053.JOEI01000033_gene4814	1.607e-78	284.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_1565908_3	28444.JODQ01000001_gene2598	5.371e-108	369.0	COG1136@1|root,COG1136@2|Bacteria,2GIV7@201174|Actinobacteria,4EGJX@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158518_k127_1565908_11	28444.JODQ01000001_gene2597	2.519e-36	162.0	COG0577@1|root,COG0577@2|Bacteria,2GNEX@201174|Actinobacteria,4EI9Q@85012|Streptosporangiales	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158518_k127_1565908_6	1394178.AWOO02000017_gene6681	5.184e-95	352.0	COG0577@1|root,COG0577@2|Bacteria,2H997@201174|Actinobacteria,4EGB7@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158518_k127_1565908_14	751944.HALDL1_11540	2.999e-09	68.0	COG2068@1|root,arCOG01873@2157|Archaea,2XY84@28890|Euryarchaeota,23WHC@183963|Halobacteria	183963|Halobacteria	S	Molybdopterin-guanine dinucleotide biosynthesis protein A	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158518_k127_1565908_10	316274.Haur_3629	3.078e-50	190.0	COG1073@1|root,COG1073@2|Bacteria,2G690@200795|Chloroflexi	200795|Chloroflexi	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
SRR25158518_k127_1565908_7	1380390.JIAT01000009_gene2069	2.988e-82	286.0	COG0697@1|root,COG0697@2|Bacteria,2I9E0@201174|Actinobacteria,4CPT5@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_1565908_13	1123013.AUIC01000005_gene1464	3.721e-16	90.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4FNI0@85023|Microbacteriaceae	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158518_k127_1565908_2	926550.CLDAP_02330	1.963e-196	630.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158518_k127_1565908_9	1121946.AUAX01000001_gene2373	7.074e-54	197.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria,4DD3B@85008|Micromonosporales	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158518_k127_1565908_4	264732.Moth_1677	1.043e-97	350.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,42FQT@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158518_k127_1565908_15	1123267.JONN01000001_gene2454	6.764e-06	59.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SRR25158518_k127_1565908_12	1382306.JNIM01000001_gene1380	7.129e-23	104.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158518_k127_1565908_5	1382306.JNIM01000001_gene1379	2.087e-95	336.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158518_k127_1565908_1	760568.Desku_2111	1.368e-211	673.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,260Q8@186807|Peptococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158518_k127_157521_0	1380393.JHVP01000005_gene3727	6.617e-56	207.0	COG1319@1|root,COG1319@2|Bacteria,2IGRP@201174|Actinobacteria	201174|Actinobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158518_k127_157521_2	500153.JOEK01000012_gene1319	1.451e-47	185.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158518_k127_157521_1	1968.JOEV01000002_gene6835	2.446e-52	203.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158518_k127_1576085_1	196162.Noca_1624	1.336e-47	172.0	COG3033@1|root,COG3033@2|Bacteria,2GKH3@201174|Actinobacteria,4DT2C@85009|Propionibacteriales	201174|Actinobacteria	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158518_k127_1576085_5	196162.Noca_3735	8.868e-08	62.0	28P5T@1|root,2ZC0N@2|Bacteria,2GP34@201174|Actinobacteria,4DNI7@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1576085_0	1353531.AZNX01000001_gene2563	8.981e-102	355.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_8
SRR25158518_k127_1576085_3	469383.Cwoe_4684	3.588e-24	111.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CSFR@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158518_k127_1576085_4	1380390.JIAT01000010_gene4578	9.177e-19	96.0	COG0797@1|root,COG0797@2|Bacteria,2GUG2@201174|Actinobacteria,4CQFM@84995|Rubrobacteria	84995|Rubrobacteria	M	Lytic transglycolase	-	-	-	-	-	-	-	-	-	-	-	-	DPBB_1
SRR25158518_k127_1576085_2	1003195.SCAT_2045	2.999e-31	139.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1586900_3	1048339.KB913029_gene16	1.038e-13	83.0	COG0823@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2931@2|Bacteria,2I7DQ@201174|Actinobacteria,4EXHP@85013|Frankiales	2|Bacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	lktA	-	-	ko:K03641,ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11,2.C.1.2	-	-	HemolysinCabind,PA,PD40,PDZ_2,Peptidase_M28,RTX,RTX_C
SRR25158518_k127_1586900_1	479434.Sthe_0833	7.973e-68	261.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158518_k127_1586900_0	504728.K649_00370	1.811e-166	538.0	COG1012@1|root,COG1012@2|Bacteria,1WJQN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.19	ko:K00137	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R02549	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158518_k127_1586900_2	266117.Rxyl_0315	2.644e-37	157.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2GIV1@201174|Actinobacteria,4CPAY@84995|Rubrobacteria	84995|Rubrobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR25158518_k127_1589472_0	754476.Q7A_3058	1.979e-71	248.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,45ZZN@72273|Thiotrichales	72273|Thiotrichales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158518_k127_1589472_1	1341151.ASZU01000021_gene1205	1.248e-68	247.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,27B88@186824|Thermoactinomycetaceae	91061|Bacilli	S	Phosphoribosyl-ATP pyrophosphohydrolase	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SRR25158518_k127_1595136_1	1121920.AUAU01000013_gene1697	2.921e-68	242.0	COG1929@1|root,COG1929@2|Bacteria	2|Bacteria	G	organic acid phosphorylation	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158518_k127_1595136_2	316274.Haur_2402	6.035e-51	192.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi,375YQ@32061|Chloroflexia	32061|Chloroflexia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158518_k127_1595136_0	211114.JOEF01000006_gene2610	7.015e-133	439.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4E0HP@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_1602475_2	485913.Krac_6715	2.595e-21	95.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158518_k127_1602475_0	521045.Kole_0242	1.174e-202	654.0	COG0058@1|root,COG0058@2|Bacteria,2GCCY@200918|Thermotogae	200918|Thermotogae	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158518_k127_1602475_1	338963.Pcar_2954	3.639e-87	306.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,43U7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	glgA-2	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Alpha-amylase,Glyco_transf_5,Glycos_transf_1
SRR25158518_k127_1603512_6	1223545.GS4_11_00590	1.126e-05	49.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4GC2H@85026|Gordoniaceae	201174|Actinobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158518_k127_1603512_3	1123322.KB904634_gene2416	7.14e-92	317.0	COG1940@1|root,COG1940@2|Bacteria,2IBV8@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158518_k127_1603512_4	1120950.KB892740_gene2598	9.358e-72	256.0	COG0279@1|root,COG0279@2|Bacteria,2GM2Q@201174|Actinobacteria,4DS8W@85009|Propionibacteriales	201174|Actinobacteria	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158518_k127_1603512_1	472759.Nhal_1480	2.576e-112	390.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria,1X09I@135613|Chromatiales	135613|Chromatiales	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158518_k127_1603512_0	1288826.MSNKSG1_14732	4.398e-138	459.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,465TZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argI	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0273,iECDH10B_1368.ECDH10B_0261,iECS88_1305.ECS88_4841,iJO1366.b0273,iJR904.b0273,iY75_1357.Y75_RS01410	OTCace,OTCace_N
SRR25158518_k127_1603512_5	1120958.AULD01000015_gene1325	2.362e-19	96.0	2BAAG@1|root,323QP@2|Bacteria,2H8F7@201174|Actinobacteria,4FSUW@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1603512_2	324602.Caur_2349	9.167e-93	318.0	COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi,377BT@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158518_k127_1639701_3	1411123.JQNH01000001_gene808	3.203e-27	111.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2U0UY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
SRR25158518_k127_1639701_4	639283.Snov_2166	2.749e-20	96.0	COG1977@1|root,COG1977@2|Bacteria,1N0ZW@1224|Proteobacteria,2UCKF@28211|Alphaproteobacteria,3EZWU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158518_k127_1639701_0	1194972.MVAC_20673	1.221e-97	326.0	COG2141@1|root,COG2141@2|Bacteria,2GPA5@201174|Actinobacteria,236QF@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_1639701_6	1382356.JQMP01000004_gene425	2.07e-07	63.0	2AD6R@1|root,312VM@2|Bacteria,2GA4D@200795|Chloroflexi,27Z79@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1639701_5	906968.Trebr_0859	1.677e-13	85.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
SRR25158518_k127_1639701_1	1499967.BAYZ01000013_gene6452	4.658e-73	256.0	COG2227@1|root,COG2227@2|Bacteria,2NRF7@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158518_k127_1639701_2	313589.JNB_15523	7.429e-73	271.0	COG4242@1|root,COG4242@2|Bacteria,2I9QV@201174|Actinobacteria,4FIU3@85021|Intrasporangiaceae	201174|Actinobacteria	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158518_k127_1650507_1	1464048.JNZS01000004_gene1268	1.945e-11	70.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4DB5X@85008|Micromonosporales	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158518_k127_1650507_2	269796.Rru_A2617	2.121e-05	55.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2JU6S@204441|Rhodospirillales	204441|Rhodospirillales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SRR25158518_k127_1650507_0	644966.Tmar_1167	1.668e-95	323.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WCRP@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158518_k127_16605_7	351607.Acel_1178	1.465e-19	99.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4EXBT@85013|Frankiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158518_k127_16605_2	1906.SFRA_07595	2.051e-42	164.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria	201174|Actinobacteria	S	BioY protein	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158518_k127_16605_3	1382306.JNIM01000001_gene2482	5.216e-40	171.0	COG3662@1|root,COG3662@2|Bacteria,2G8VS@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
SRR25158518_k127_16605_1	1254432.SCE1572_08545	2.007e-45	182.0	COG1247@1|root,COG1247@2|Bacteria,1RGU8@1224|Proteobacteria,43B5R@68525|delta/epsilon subdivisions,2X6JB@28221|Deltaproteobacteria,2YVMN@29|Myxococcales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SRR25158518_k127_16605_5	357808.RoseRS_0293	2.228e-31	139.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158518_k127_16605_8	479434.Sthe_2947	3.197e-18	93.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi	200795|Chloroflexi	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158518_k127_16605_6	358396.C445_17049	2.964e-27	128.0	arCOG12670@1|root,arCOG12670@2157|Archaea,2XXAX@28890|Euryarchaeota,23VWQ@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_16605_0	479432.Sros_3301	1.129e-107	380.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4EFW4@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,P_proprotein,Peptidase_S8
SRR25158518_k127_16605_4	525904.Tter_2060	1.821e-34	153.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR25158518_k127_16605_9	340099.Teth39_0476	7.615e-07	54.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,249R4@186801|Clostridia,42FJA@68295|Thermoanaerobacterales	186801|Clostridia	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158518_k127_1701202_10	751945.Theos_0856	2.334e-15	89.0	COG1225@1|root,COG1225@2|Bacteria,1WI9E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158518_k127_1701202_6	316274.Haur_2676	1.163e-32	140.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi,375VW@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Thiamin pyrophosphokinase, catalytic region	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
SRR25158518_k127_1701202_7	926569.ANT_16160	4.709e-31	129.0	COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158518_k127_1701202_12	1122212.AULO01000012_gene1098	1.227e-05	56.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,1XIXJ@135619|Oceanospirillales	135619|Oceanospirillales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
SRR25158518_k127_1701202_0	570268.ANBB01000053_gene2972	1.11e-147	495.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4EHBJ@85012|Streptosporangiales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158518_k127_1701202_5	867903.ThesuDRAFT_01803	9.204e-36	158.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158518_k127_1701202_8	926550.CLDAP_24350	1.149e-30	134.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
SRR25158518_k127_1701202_1	1380347.JNII01000005_gene3721	2.7e-96	336.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4ES6N@85013|Frankiales	201174|Actinobacteria	E	PFAM ABC transporter	-	-	3.6.3.21	ko:K02028,ko:K02029,ko:K10008	ko02010,map02010	M00233,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.9	-	-	ABC_tran,BPD_transp_1
SRR25158518_k127_1701202_2	479432.Sros_9352	4.688e-85	292.0	COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4EGKS@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,DUF2808,SBP_bac_3
SRR25158518_k127_1701202_3	110319.CF8_2574	9.642e-72	256.0	COG0834@1|root,COG0834@2|Bacteria,2GN3G@201174|Actinobacteria,4DNI8@85009|Propionibacteriales	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	M00234,M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14,3.A.1.3.20	-	-	SBP_bac_3
SRR25158518_k127_1701202_4	525904.Tter_0552	5.698e-70	249.0	COG2378@1|root,COG2378@2|Bacteria,2NPY6@2323|unclassified Bacteria	2|Bacteria	K	WYL domain	-	-	-	ko:K07012,ko:K13572	-	-	-	-	ko00000,ko01000,ko02048,ko03051	-	-	-	DEAD,HD,HTH_11,WYL
SRR25158518_k127_1701202_11	1345695.CLSA_c37380	1.368e-07	63.0	COG2340@1|root,COG5263@1|root,COG2340@2|Bacteria,COG5263@2|Bacteria,1V6GZ@1239|Firmicutes,24I20@186801|Clostridia,36VHI@31979|Clostridiaceae	186801|Clostridia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CW_binding_1
SRR25158518_k127_1701202_9	330214.NIDE3049	1.176e-22	101.0	COG1078@1|root,COG1078@2|Bacteria,3J0YB@40117|Nitrospirae	40117|Nitrospirae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158518_k127_1715104_2	190650.CC_0014	1.044e-12	79.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2KGJZ@204458|Caulobacterales	204458|Caulobacterales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158518_k127_1715104_0	1210045.ALNP01000008_gene4596	1.457e-71	273.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria	201174|Actinobacteria	H	Molybdenum cofactor synthesis domain protein	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158518_k127_1715104_1	1906.SFRA_07890	6.733e-44	182.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158518_k127_1715104_3	1176165.CAJD01000019_gene1620	2.029e-11	73.0	COG4478@1|root,COG4478@2|Bacteria,2IFW4@201174|Actinobacteria,4F8AU@85019|Brevibacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
SRR25158518_k127_1715104_4	1122132.AQYH01000010_gene3770	4.604e-07	56.0	COG3743@1|root,COG3743@2|Bacteria,1RA3K@1224|Proteobacteria,2U7GQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4332)	MA20_15755	-	-	-	-	-	-	-	-	-	-	-	DUF4332
SRR25158518_k127_1740905_2	469383.Cwoe_5289	2.278e-25	108.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CQ0I@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158518_k127_1740905_1	525904.Tter_0795	6.756e-56	209.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158518_k127_1740905_0	1157490.EL26_05255	2.102e-155	501.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,277WB@186823|Alicyclobacillaceae	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
SRR25158518_k127_1742405_0	709986.Deima_1751	4.49e-321	1007.0	COG0178@1|root,COG0178@2|Bacteria,1WI7J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158518_k127_1742405_3	926550.CLDAP_25850	4.739e-15	80.0	2ERYI@1|root,33JHP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1742405_1	357808.RoseRS_3707	9.384e-30	128.0	COG2020@1|root,COG2020@2|Bacteria,2G9T5@200795|Chloroflexi,3761T@32061|Chloroflexia	32061|Chloroflexia	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158518_k127_1742405_2	1122622.ATWJ01000008_gene2806	1.106e-20	95.0	COG1670@1|root,COG1670@2|Bacteria,2IKXU@201174|Actinobacteria,4FH6G@85021|Intrasporangiaceae	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158518_k127_1743925_12	235985.BBPN01000038_gene466	1.072e-24	108.0	COG3832@1|root,COG3832@2|Bacteria,2GSCI@201174|Actinobacteria,2NIR2@228398|Streptacidiphilus	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158518_k127_1743925_10	479434.Sthe_1805	6.184e-28	127.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi,27YJB@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158518_k127_1743925_13	644282.Deba_2400	1.883e-24	104.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158518_k127_1743925_14	867845.KI911784_gene427	3.629e-22	100.0	COG0254@1|root,COG0254@2|Bacteria,2G75A@200795|Chloroflexi,375Y4@32061|Chloroflexia	32061|Chloroflexia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158518_k127_1743925_16	333138.LQ50_25110	4.518e-12	76.0	COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HEAP@91061|Bacilli,1ZCZZ@1386|Bacillus	91061|Bacilli	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_5
SRR25158518_k127_1743925_5	311424.DhcVS_1501	7.075e-60	232.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,34CZ8@301297|Dehalococcoidia	301297|Dehalococcoidia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_1743925_8	552811.Dehly_1707	6.9e-35	143.0	COG5658@1|root,COG5658@2|Bacteria,2G714@200795|Chloroflexi,34CN7@301297|Dehalococcoidia	301297|Dehalococcoidia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
SRR25158518_k127_1743925_11	1502851.FG93_02665	1.669e-26	115.0	COG0640@1|root,COG0640@2|Bacteria,1ND8B@1224|Proteobacteria,2UI6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158518_k127_1743925_2	671143.DAMO_2491	7.063e-74	258.0	COG1028@1|root,COG1028@2|Bacteria,2NQBD@2323|unclassified Bacteria	2|Bacteria	IQ	NAD(P)H binding domain of trans-2-enoyl-CoA reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158518_k127_1743925_4	1122939.ATUD01000001_gene51	1.248e-60	232.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CQ0G@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158518_k127_1743925_6	1051632.TPY_3740	2.076e-37	154.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158518_k127_1743925_7	562970.Btus_2659	6.993e-36	146.0	COG4097@1|root,COG4097@2|Bacteria,1VAMR@1239|Firmicutes,4HKN3@91061|Bacilli,278P1@186823|Alicyclobacillaceae	91061|Bacilli	P	Ferric reductase like transmembrane component	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
SRR25158518_k127_1743925_3	479434.Sthe_2977	5.713e-63	229.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,27XHP@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158518_k127_1743925_15	309801.trd_A0182	9.467e-22	111.0	COG0735@1|root,COG0735@2|Bacteria,2G74Y@200795|Chloroflexi,27YIH@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158518_k127_1743925_0	479434.Sthe_2975	2.569e-75	271.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,27XKB@189775|Thermomicrobia	189775|Thermomicrobia	P	ABC 3 transport family	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158518_k127_1743925_1	479434.Sthe_2976	4.97e-74	260.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi,27XH6@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR25158518_k127_1743925_9	1382356.JQMP01000003_gene1647	5.963e-30	131.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158518_k127_1747988_0	1158182.KB905021_gene731	0.0	1033.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158518_k127_1747988_2	1040989.AWZU01000014_gene4548	2.926e-81	307.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,3JSVF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158518_k127_1747988_5	671143.DAMO_0414	2.102e-30	134.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SRR25158518_k127_1747988_4	479434.Sthe_0419	1.842e-71	258.0	COG0842@1|root,COG0842@2|Bacteria,2G8I5@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_1747988_3	479434.Sthe_0418	1.015e-80	285.0	COG1131@1|root,COG1131@2|Bacteria,2G7S9@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158518_k127_1747988_1	648885.KB316283_gene3192	9.116e-123	408.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,1JR9D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
SRR25158518_k127_1747988_6	926569.ANT_14000	1.71e-16	93.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
SRR25158518_k127_1750795_2	42565.FP66_12455	3.093e-48	189.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBD@135619|Oceanospirillales	135619|Oceanospirillales	EH	COG0147 Anthranilate para-aminobenzoate synthases component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158518_k127_1750795_1	1283299.AUKG01000001_gene2098	2.725e-126	416.0	COG3191@1|root,COG3191@2|Bacteria,2H89D@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM peptidase S58, DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158518_k127_1750795_4	479432.Sros_8224	2.011e-34	147.0	COG0454@1|root,COG0454@2|Bacteria,2I5F6@201174|Actinobacteria	201174|Actinobacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1750795_5	298654.FraEuI1c_5729	5.166e-24	109.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4ESTA@85013|Frankiales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_1750795_6	1214242.B446_08255	4.215e-15	88.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158518_k127_1750795_3	41431.PCC8801_2475	2.797e-35	145.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,3KGMC@43988|Cyanothece	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
SRR25158518_k127_1750795_0	926569.ANT_25010	7.544e-143	460.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
SRR25158518_k127_1764598_1	1035308.AQYY01000001_gene3255	1.947e-46	186.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META,YscW
SRR25158518_k127_1764598_0	1341151.ASZU01000004_gene349	1.186e-49	184.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,27B2I@186824|Thermoactinomycetaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158518_k127_1775337_3	1380347.JNII01000011_gene909	1.284e-63	224.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4ESDU@85013|Frankiales	201174|Actinobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158518_k127_1775337_1	1038858.AXBA01000001_gene3229	6.45e-80	288.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,3EYYC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158518_k127_1775337_0	59538.XP_005980494.1	6.94e-141	484.0	COG0133@1|root,COG0135@1|root,KOG1395@2759|Eukaryota,KOG4202@2759|Eukaryota,38GS5@33154|Opisthokonta,3BXKZ@33208|Metazoa,3DED1@33213|Bilateria	33208|Metazoa	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP,PRAI
SRR25158518_k127_1775337_4	1382306.JNIM01000001_gene2652	3.952e-54	203.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158518_k127_1775337_5	35754.JNYJ01000043_gene4416	4.652e-53	195.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4DK0U@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1775337_2	1379270.AUXF01000003_gene3787	7.257e-70	253.0	COG0008@1|root,COG0008@2|Bacteria,1ZURR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
SRR25158518_k127_1775337_8	1121440.AUMA01000007_gene1065	2.459e-09	68.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2M8FM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158518_k127_1775337_6	1123367.C666_09785	1.174e-39	160.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,2KWH7@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158518_k127_1775337_7	864563.HMPREF9166_2213	1.875e-26	115.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4H2Y4@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
SRR25158518_k127_1783102_2	765420.OSCT_1634	2.196e-14	87.0	COG1969@1|root,COG1969@2|Bacteria,2GAHC@200795|Chloroflexi,37655@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158518_k127_1783102_0	383372.Rcas_3147	2.252e-260	812.0	COG0374@1|root,COG0374@2|Bacteria,2G6SF@200795|Chloroflexi,376Y8@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SRR25158518_k127_1783102_1	765420.OSCT_1632	3.686e-123	410.0	COG1740@1|root,COG1740@2|Bacteria,2G8F0@200795|Chloroflexi,376S5@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM hydrogenase (NiFe) small subunit HydA	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
SRR25158518_k127_1783102_3	511051.CSE_14860	5.57e-08	56.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158518_k127_1787050_0	1343739.PAP_07605	1.063e-173	556.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR25158518_k127_1787050_1	391625.PPSIR1_39870	7.595e-116	396.0	COG0479@1|root,COG0543@1|root,COG0479@2|Bacteria,COG0543@2|Bacteria,1QVWG@1224|Proteobacteria,43BWA@68525|delta/epsilon subdivisions,2X771@28221|Deltaproteobacteria,2YUJP@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SRR25158518_k127_1789233_0	497964.CfE428DRAFT_6224	7.65e-125	419.0	COG1384@1|root,COG1384@2|Bacteria	2|Bacteria	J	tRNA binding	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
SRR25158518_k127_1789233_3	357808.RoseRS_0077	7.044e-39	162.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi,375ID@32061|Chloroflexia	32061|Chloroflexia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158518_k127_1789233_4	477974.Daud_1030	1.305e-28	125.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,2625T@186807|Peptococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158518_k127_1789233_2	477974.Daud_0835	5.644e-56	205.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,260XY@186807|Peptococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158518_k127_1789233_1	3649.evm.model.supercontig_176.21	5.047e-112	371.0	COG3808@1|root,2QPJC@2759|Eukaryota,37IY7@33090|Viridiplantae,3GCJM@35493|Streptophyta,3HYTV@3699|Brassicales	35493|Streptophyta	C	Pyrophosphate-energized membrane proton pump	-	GO:0000139,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005773,GO:0005794,GO:0005802,GO:0006810,GO:0008150,GO:0009678,GO:0012505,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0022804,GO:0022857,GO:0031090,GO:0031410,GO:0031982,GO:0031984,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0097708,GO:0098588,GO:0098791	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	H_PPase
SRR25158518_k127_182301_0	981369.JQMJ01000003_gene7428	5.648e-21	102.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,2NHED@228398|Streptacidiphilus	201174|Actinobacteria	K	ECF sigma factor	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_182301_1	1463825.JNXC01000017_gene7024	4.27e-13	82.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria,4DY93@85010|Pseudonocardiales	201174|Actinobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,PD40
SRR25158518_k127_1829157_1	1120934.KB894436_gene4372	9.587e-103	348.0	COG0182@1|root,COG0182@2|Bacteria,2GJJA@201174|Actinobacteria,4DZKT@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,IF-2B
SRR25158518_k127_1829157_0	521098.Aaci_0705	2.921e-129	450.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,4HB28@91061|Bacilli	91061|Bacilli	IQ	dehydrogenase	yuxG	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
SRR25158518_k127_1875176_2	1297569.MESS2_960003	3.096e-54	197.0	COG4608@1|root,COG4608@2|Bacteria,1NU61@1224|Proteobacteria,2UR5X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158518_k127_1875176_0	526225.Gobs_1485	6.712e-92	312.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4ESB1@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_1875176_4	526225.Gobs_1484	1.616e-45	188.0	COG1277@1|root,COG1277@2|Bacteria,2GKW6@201174|Actinobacteria,4ERMU@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158518_k127_1875176_5	1283299.AUKG01000001_gene1932	1.173e-35	154.0	COG2385@1|root,COG2385@2|Bacteria,2ID9T@201174|Actinobacteria,4CPMQ@84995|Rubrobacteria	84995|Rubrobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
SRR25158518_k127_1875176_6	1151061.CAJY01000022_gene3954	5.166e-15	83.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
SRR25158518_k127_1875176_7	1121116.KB894783_gene58	3.378e-13	79.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2VHMU@28216|Betaproteobacteria,4ABA8@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM heat shock protein DnaJ domain protein	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158518_k127_1875176_1	1121456.ATVA01000019_gene1273	8.768e-69	241.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MB6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158518_k127_1875176_3	1380356.JNIK01000011_gene1706	9.125e-48	185.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4ETC8@85013|Frankiales	201174|Actinobacteria	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_1885986_3	1206737.BAGF01000051_gene3180	8.232e-20	91.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4FX5P@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158518_k127_1885986_1	292459.STH1159	1.397e-45	176.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158518_k127_1885986_2	1128421.JAGA01000002_gene404	1.792e-34	143.0	COG0632@1|root,COG0632@2|Bacteria,2NPR6@2323|unclassified Bacteria	2|Bacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158518_k127_1885986_0	1449976.KALB_4354	6.524e-62	228.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4E9EG@85010|Pseudonocardiales	201174|Actinobacteria	CG	Glycosyltransferase family 28 C-terminal domain	-	-	-	ko:K16039	ko01051,ko01130,map01051,map01130	-	R09857	RC00005,RC02843	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158518_k127_1888947_1	1122182.KB903834_gene5856	1.741e-12	77.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4DM51@85008|Micromonosporales	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158518_k127_1888947_2	1380390.JIAT01000011_gene2781	6.078e-07	61.0	COG0346@1|root,COG0346@2|Bacteria,2HQUH@201174|Actinobacteria,4CSM4@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158518_k127_1888947_0	1121272.KB903261_gene6265	1.538e-18	96.0	2BWWR@1|root,2ZG0F@2|Bacteria,2IJ2X@201174|Actinobacteria,4DDGM@85008|Micromonosporales	201174|Actinobacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158518_k127_1890461_0	1423816.BACQ01000010_gene351	5.039e-276	891.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae	91061|Bacilli	F	Carbamoyl-phosphate synthase	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158518_k127_1890461_1	479434.Sthe_0935	3.189e-100	339.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,27XJV@189775|Thermomicrobia	189775|Thermomicrobia	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158518_k127_1890461_3	1382304.JNIL01000001_gene1305	7.7e-47	187.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,4ISRX@91061|Bacilli,278GK@186823|Alicyclobacillaceae	91061|Bacilli	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158518_k127_1890461_2	935866.JAER01000043_gene2462	1.574e-52	196.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DNTF@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_1894118_2	926550.CLDAP_01170	2.253e-25	116.0	COG0747@1|root,COG0747@2|Bacteria,2G6MN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158518_k127_1894118_1	266117.Rxyl_0136	1.898e-98	342.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4CQ4C@84995|Rubrobacteria	84995|Rubrobacteria	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158518_k127_1894118_4	105425.BBPL01000022_gene916	1.553e-09	68.0	COG3291@1|root,COG3291@2|Bacteria,2GKNE@201174|Actinobacteria	201174|Actinobacteria	NU	Collagenase	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,PPC,Peptidase_M9,Peptidase_M9_N
SRR25158518_k127_1894118_0	644966.Tmar_0682	4.002e-153	508.0	COG2355@1|root,COG2355@2|Bacteria,1TRNQ@1239|Firmicutes,24M4R@186801|Clostridia	186801|Clostridia	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158518_k127_1894118_3	1284679.HMPREF1626_02800	2.157e-11	64.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4D4UY@85005|Actinomycetales	201174|Actinobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158518_k127_1903464_0	1040986.ATYO01000012_gene5293	5.296e-214	703.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYI3@28211|Alphaproteobacteria,43RTK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_9,Response_reg
SRR25158518_k127_1903464_5	926569.ANT_09060	0.0005803	54.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg
SRR25158518_k127_1903464_1	420324.KI911972_gene3032	8.687e-81	290.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,1JYYS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
SRR25158518_k127_1903464_4	1284680.HMPREF1627_03805	5.601e-05	54.0	2EGCD@1|root,33A46@2|Bacteria,2I66V@201174|Actinobacteria,4D5QZ@85005|Actinomycetales	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
SRR25158518_k127_1903464_2	494419.ALPM01000010_gene705	4.404e-74	264.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,1W7Q6@1268|Micrococcaceae	201174|Actinobacteria	GK	Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158518_k127_1903464_3	1035308.AQYY01000001_gene2445	1.711e-27	115.0	COG1226@1|root,COG1226@2|Bacteria,1V2CY@1239|Firmicutes,24DT6@186801|Clostridia,260Z7@186807|Peptococcaceae	186801|Clostridia	P	PFAM TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158518_k127_1908204_0	861299.J421_0915	4.165e-88	306.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158518_k127_1908204_1	264732.Moth_1000	6.534e-14	82.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158518_k127_1911091_0	1285583.CCASEI_06060	8.218e-75	261.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,22KFY@1653|Corynebacteriaceae	201174|Actinobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158518_k127_1911091_1	428125.CLOLEP_01183	7.246e-47	188.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158518_k127_1911091_2	1382306.JNIM01000001_gene3883	1.453e-45	169.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158518_k127_1911091_3	1382356.JQMP01000004_gene452	0.0006157	48.0	COG0227@1|root,COG0227@2|Bacteria,2G9W5@200795|Chloroflexi,27Z9I@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal L28 family	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158518_k127_1912692_1	926569.ANT_12940	4.279e-76	274.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SRR25158518_k127_1912692_3	1121866.AUGK01000013_gene1906	6.527e-36	147.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CU8U@84998|Coriobacteriia	84998|Coriobacteriia	D	Part of the ABC transporter FtsEX involved in cellular division	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158518_k127_1912692_0	1123311.KB904470_gene1233	1.224e-77	278.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli	91061|Bacilli	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158518_k127_1912692_4	1121106.JQKB01000059_gene4749	4.548e-22	110.0	COG0454@1|root,COG0456@2|Bacteria,1R418@1224|Proteobacteria,2U1QH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_1912692_2	266117.Rxyl_1620	4.295e-45	166.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CPCP@84995|Rubrobacteria	84995|Rubrobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158518_k127_1913446_0	85643.Tmz1t_0420	6.85e-119	396.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	206389|Rhodocyclales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158518_k127_1913446_3	1123065.ATWL01000020_gene3569	5.568e-38	149.0	COG2606@1|root,COG2606@2|Bacteria,2IIIW@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158518_k127_1913446_4	519442.Huta_1286	1.326e-22	106.0	arCOG02399@1|root,arCOG02399@2157|Archaea,2XVVI@28890|Euryarchaeota,23UYC@183963|Halobacteria	183963|Halobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158518_k127_1913446_5	519442.Huta_1285	3.683e-19	97.0	arCOG06181@1|root,arCOG06181@2157|Archaea,2Y06C@28890|Euryarchaeota,23XFD@183963|Halobacteria	183963|Halobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1913446_1	1128421.JAGA01000002_gene35	9.653e-69	245.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158518_k127_1913446_2	42256.RradSPS_2370	2.584e-53	196.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4CTMV@84995|Rubrobacteria	84995|Rubrobacteria	M	Capsule synthesis protein, CapA	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158518_k127_1914136_2	1150864.MILUP08_45108	5.558e-29	126.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4DBBD@85008|Micromonosporales	201174|Actinobacteria	S	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158518_k127_1914136_3	1097668.BYI23_C012830	4.765e-07	59.0	COG1309@1|root,COG1309@2|Bacteria,1RFAP@1224|Proteobacteria,2WECK@28216|Betaproteobacteria,1K74U@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158518_k127_1914136_0	404589.Anae109_0855	2.327e-218	687.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJZJ@28221|Deltaproteobacteria,2Z2XA@29|Myxococcales	28221|Deltaproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158518_k127_1914136_1	404589.Anae109_0854	9.518e-192	606.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158518_k127_1915420_2	1131462.DCF50_p1855	2.435e-19	103.0	COG2373@1|root,COG2373@2|Bacteria,1TRBD@1239|Firmicutes,24CW4@186801|Clostridia,264R2@186807|Peptococcaceae	186801|Clostridia	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N_2,Big_5,Dockerin_1,zf-HC2
SRR25158518_k127_1915420_1	292564.Cyagr_2062	1.906e-45	176.0	COG0193@1|root,COG0193@2|Bacteria,1G0D0@1117|Cyanobacteria,22S7C@167375|Cyanobium	1117|Cyanobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158518_k127_1915420_0	383372.Rcas_1478	5.425e-269	874.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi,375DR@32061|Chloroflexia	32061|Chloroflexia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158518_k127_1921510_1	326427.Cagg_3437	4.153e-53	200.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi,376R0@32061|Chloroflexia	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158518_k127_1921510_5	273075.Ta1414	9.808e-23	108.0	COG0425@1|root,arCOG02062@2157|Archaea,2XZUG@28890|Euryarchaeota	28890|Euryarchaeota	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
SRR25158518_k127_1921510_2	1240349.ANGC01000014_gene642	4.655e-46	173.0	COG2210@1|root,COG2210@2|Bacteria,2HGHZ@201174|Actinobacteria,4FXJI@85025|Nocardiaceae	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158518_k127_1921510_6	319225.Plut_0033	1.987e-17	94.0	COG0425@1|root,COG0425@2|Bacteria,1FE4M@1090|Chlorobi	1090|Chlorobi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158518_k127_1921510_4	351607.Acel_0525	3.807e-24	107.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EWZZ@85013|Frankiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158518_k127_1921510_7	926560.KE387023_gene1421	3.74e-16	82.0	COG0640@1|root,COG0640@2|Bacteria,1WK64@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158518_k127_1921510_3	357808.RoseRS_2070	1.79e-26	117.0	COG2606@1|root,COG2606@2|Bacteria,2G8TA@200795|Chloroflexi,377ER@32061|Chloroflexia	32061|Chloroflexia	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158518_k127_1921510_8	1131812.JQMS01000001_gene765	1.431e-05	55.0	2BK9M@1|root,32EPT@2|Bacteria,4NQGA@976|Bacteroidetes,1I2SP@117743|Flavobacteriia,2NWJ8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1923262_1	314230.DSM3645_04355	3.22e-34	134.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158518_k127_1923262_2	530564.Psta_0808	9.418e-22	105.0	COG0517@1|root,COG0517@2|Bacteria,2J0MQ@203682|Planctomycetes	203682|Planctomycetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158518_k127_1923262_0	1306990.BARG01000102_gene9631	6.648e-102	351.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158518_k127_1946373_1	1298863.AUEP01000007_gene351	1.081e-136	444.0	COG1226@1|root,COG1226@2|Bacteria,2HZRR@201174|Actinobacteria,4DTS4@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_N
SRR25158518_k127_1946373_3	2002.JOEQ01000037_gene4325	4.238e-61	236.0	COG5637@1|root,COG5637@2|Bacteria,2GP5P@201174|Actinobacteria,4EJVD@85012|Streptosporangiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158518_k127_1946373_0	2002.JOEQ01000037_gene4324	1.561e-183	599.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4EFZC@85012|Streptosporangiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158518_k127_1946373_5	483219.LILAB_00920	3.769e-27	124.0	28PTG@1|root,2ZCEQ@2|Bacteria,1PCZF@1224|Proteobacteria,433WM@68525|delta/epsilon subdivisions,2X292@28221|Deltaproteobacteria,2YXC4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_1946373_2	536227.CcarbDRAFT_4777	1.977e-74	259.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
SRR25158518_k127_1946373_6	1150398.JIBJ01000004_gene2968	6.06e-05	52.0	COG3794@1|root,COG3794@2|Bacteria,2GS7W@201174|Actinobacteria	201174|Actinobacteria	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158518_k127_1946373_4	1380390.JIAT01000009_gene1628	1.216e-37	159.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158518_k127_1948310_1	446462.Amir_3077	5.539e-151	488.0	COG1012@1|root,COG1012@2|Bacteria,2HF1C@201174|Actinobacteria,4EA29@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158518_k127_1948310_6	452637.Oter_3300	6.18e-41	172.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR25158518_k127_1948310_0	1123251.ATWM01000004_gene1975	2.012e-153	517.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4FFF5@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22,4.1.1.64	ko:K00596,ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158518_k127_1948310_5	861299.J421_0074	7.577e-43	166.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158518_k127_1948310_2	1206744.BAGL01000033_gene220	9.662e-120	393.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4FZB8@85025|Nocardiaceae	201174|Actinobacteria	I	Coenzyme A transferase	catI	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158518_k127_1948310_3	926569.ANT_02010	2.675e-79	286.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158518_k127_1948310_8	4565.Traes_2DL_60E7852F7.2	8.03e-17	92.0	COG0589@1|root,2RZF9@2759|Eukaryota,37V17@33090|Viridiplantae,3GISS@35493|Streptophyta,3M009@4447|Liliopsida,3IHI6@38820|Poales	35493|Streptophyta	T	Universal stress protein family	-	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158518_k127_1948310_4	1128421.JAGA01000001_gene2386	3.962e-50	183.0	COG2132@1|root,COG2132@2|Bacteria,2NPD2@2323|unclassified Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,DUF4396
SRR25158518_k127_1950154_1	1382306.JNIM01000001_gene38	1.358e-59	227.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158518_k127_1950154_2	309801.trd_1507	7.584e-34	151.0	COG1546@1|root,COG1546@2|Bacteria,2G6U8@200795|Chloroflexi,27YG1@189775|Thermomicrobia	189775|Thermomicrobia	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
SRR25158518_k127_1950154_3	635013.TherJR_1418	1.569e-15	89.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,261QR@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158518_k127_1950154_0	717606.PaecuDRAFT_0633	5.454e-63	222.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,26QH8@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158518_k127_1950350_5	390989.JOEG01000004_gene3969	3.188e-23	111.0	COG1247@1|root,COG1247@2|Bacteria,2GJ8T@201174|Actinobacteria,4DMS3@85008|Micromonosporales	201174|Actinobacteria	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_1950350_0	1050202.KB913024_gene1080	9.191e-135	439.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,408UP@622450|Actinopolysporales	201174|Actinobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158518_k127_1950350_3	1123023.JIAI01000001_gene6559	1.773e-85	308.0	COG0252@1|root,COG0252@2|Bacteria,2HUB2@201174|Actinobacteria,4E3K5@85010|Pseudonocardiales	201174|Actinobacteria	EJ	Asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
SRR25158518_k127_1950350_2	1128421.JAGA01000002_gene1381	5.036e-90	318.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
SRR25158518_k127_1950350_6	570268.ANBB01000056_gene37	0.0002764	51.0	COG1846@1|root,COG1846@2|Bacteria,2GT6K@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158518_k127_1950350_4	479434.Sthe_2651	1.443e-77	270.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,27XR5@189775|Thermomicrobia	189775|Thermomicrobia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158518_k127_1950350_1	1382306.JNIM01000001_gene105	4.549e-113	380.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158518_k127_1958523_1	1121468.AUBR01000010_gene2426	1.021e-58	225.0	COG0702@1|root,COG0702@2|Bacteria,1TWZS@1239|Firmicutes,24EGR@186801|Clostridia,42H7V@68295|Thermoanaerobacterales	186801|Clostridia	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
SRR25158518_k127_1958523_0	1123075.AUDP01000015_gene3335	7.18e-62	226.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia,3WJ1S@541000|Ruminococcaceae	186801|Clostridia	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
SRR25158518_k127_1958523_2	1151117.AJLF01000002_gene561	3.562e-30	130.0	COG0647@1|root,arCOG04221@2157|Archaea,2XTCH@28890|Euryarchaeota,24345@183968|Thermococci	183968|Thermococci	G	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158518_k127_1976037_0	1122933.JNIY01000003_gene251	3.529e-69	244.0	COG0702@1|root,COG0702@2|Bacteria,2GKXI@201174|Actinobacteria,4F2I0@85016|Cellulomonadaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA,SnoaL_2
SRR25158518_k127_1976037_1	1380346.JNIH01000006_gene3460	1.055e-63	231.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
SRR25158518_k127_1976037_2	926560.KE387027_gene419	3.44e-45	171.0	COG0477@1|root,COG0477@2|Bacteria,1WMC1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_199143_0	1382306.JNIM01000001_gene977	5.229e-55	209.0	COG0477@1|root,COG2814@2|Bacteria	1382306.JNIM01000001_gene977|-	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_199143_1	1007103.AFHW01000092_gene3618	1.719e-49	188.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158518_k127_199523_6	697281.Mahau_1544	3.056e-29	136.0	COG1668@1|root,COG1668@2|Bacteria,1UIA3@1239|Firmicutes,25EF1@186801|Clostridia	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158518_k127_199523_1	886293.Sinac_6012	1.136e-96	327.0	COG1131@1|root,COG1131@2|Bacteria,2IXVN@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_199523_3	1128421.JAGA01000003_gene3523	2.886e-67	258.0	COG0318@1|root,COG0318@2|Bacteria,2NR5F@2323|unclassified Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	MA20_41400	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158518_k127_199523_2	1382306.JNIM01000001_gene1141	1.066e-79	284.0	COG4198@1|root,COG4198@2|Bacteria,2G6FC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158518_k127_199523_7	33898.JRHJ01000010_gene5001	8.637e-21	103.0	COG2267@1|root,COG2267@2|Bacteria,2I8UI@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
SRR25158518_k127_199523_5	926560.KE387027_gene705	4.525e-42	163.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
SRR25158518_k127_199523_8	926560.KE387027_gene706	2.418e-10	75.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	2.1.1.14	ko:K00549,ko:K04085	ko00270,ko00450,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map01100,map01110,map01230,map04122	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Meth_synt_2,OsmC,SnoaL_2,TusA
SRR25158518_k127_199523_0	1380390.JIAT01000014_gene6115	1.938e-135	468.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4CSK4@84995|Rubrobacteria	84995|Rubrobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158518_k127_1998368_2	926569.ANT_14000	4.423e-28	122.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
SRR25158518_k127_1998368_6	871963.Desdi_1270	3.218e-05	57.0	COG1266@1|root,COG1266@2|Bacteria,1V4WD@1239|Firmicutes,24P4C@186801|Clostridia,261SJ@186807|Peptococcaceae	186801|Clostridia	S	PFAM CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158518_k127_1998368_1	926550.CLDAP_08060	2.193e-65	233.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158518_k127_1998368_5	1132509.C447_07078	1.584e-05	57.0	arCOG02498@1|root,arCOG02498@2157|Archaea,2Y82I@28890|Euryarchaeota,2413G@183963|Halobacteria	183963|Halobacteria	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158518_k127_1998368_0	1382356.JQMP01000003_gene1688	1.837e-67	245.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_1998368_3	1382306.JNIM01000001_gene2710	1.938e-24	118.0	COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi	200795|Chloroflexi	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
SRR25158518_k127_1998368_4	1206744.BAGL01000042_gene1249	2.344e-20	99.0	COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,2HEI2@201174|Actinobacteria,4FV0Z@85025|Nocardiaceae	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158518_k127_2007380_1	479434.Sthe_3187	2.428e-21	100.0	COG3871@1|root,COG3871@2|Bacteria,2G9DN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158518_k127_2007380_0	926569.ANT_05580	6.866e-74	263.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158518_k127_2007380_2	1175629.AJTG01000007_gene1133	8.372e-09	63.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,27DR0@186827|Aerococcaceae	91061|Bacilli	S	AI-2E family transporter	XK27_05220	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_2011067_1	1297742.A176_04485	1.674e-85	291.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780	A_deaminase
SRR25158518_k127_2011067_2	1246459.KB898357_gene1721	1.173e-32	137.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,2UM46@28211|Alphaproteobacteria,4BB5E@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158518_k127_2011067_0	1128421.JAGA01000003_gene3234	8.729e-116	394.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
SRR25158518_k127_2037346_3	886293.Sinac_4483	2.929e-65	231.0	COG1526@1|root,COG1526@2|Bacteria,2IZ61@203682|Planctomycetes	203682|Planctomycetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158518_k127_2037346_6	406552.NJ7G_2578	1.022e-30	127.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XYD4@28890|Euryarchaeota,23W3F@183963|Halobacteria	183963|Halobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158518_k127_2037346_4	316274.Haur_4401	3.499e-61	227.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158518_k127_2037346_0	1223523.H340_16456	3.801e-97	336.0	COG0019@1|root,COG0019@2|Bacteria,2HHG9@201174|Actinobacteria	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158518_k127_2037346_8	1229781.C272_08637	6.488e-14	84.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4FAI1@85019|Brevibacteriaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SRR25158518_k127_2037346_2	1122611.KB903964_gene4908	3.886e-68	239.0	COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4EI87@85012|Streptosporangiales	201174|Actinobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158518_k127_2037346_1	1047013.AQSP01000017_gene1088	9.742e-88	308.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158518_k127_2037346_5	391625.PPSIR1_27718	2.457e-33	145.0	COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,42R4X@68525|delta/epsilon subdivisions,2WN1E@28221|Deltaproteobacteria,2YU8W@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10110,ko:K15772	ko02010,map02010	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	BPD_transp_1
SRR25158518_k127_2037346_7	593907.Celgi_2435	5.131e-28	132.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4F0M5@85016|Cellulomonadaceae	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,TM_PBP2_N
SRR25158518_k127_204257_3	219305.MCAG_01070	1.656e-29	126.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4DDIB@85008|Micromonosporales	201174|Actinobacteria	L	U mismatch-specific DNA glycosylase	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158518_k127_204257_0	1125863.JAFN01000001_gene1858	7.557e-102	349.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158518_k127_204257_2	1112204.GPOL_c31560	3.05e-33	145.0	COG0628@1|root,COG0628@2|Bacteria,2GM01@201174|Actinobacteria,4GD0S@85026|Gordoniaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_204257_1	926560.KE387023_gene2055	2.059e-54	195.0	COG0446@1|root,COG0446@2|Bacteria,1WI8N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	FAD-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158518_k127_2042676_2	869209.Tresu_0908	4.308e-17	95.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
SRR25158518_k127_2042676_0	290397.Adeh_2624	1.205e-74	267.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158518_k127_2042676_3	357808.RoseRS_2150	1.441e-14	87.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158518_k127_2042676_1	1286171.EAL2_c07660	1.589e-45	182.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,25VD7@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158518_k127_2051604_3	1047013.AQSP01000144_gene790	6.053e-98	332.0	COG2089@1|root,COG2089@2|Bacteria,2NPHD@2323|unclassified Bacteria	2|Bacteria	M	SAF	neuB	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
SRR25158518_k127_2051604_0	1123392.AQWL01000009_gene1057	2.593e-185	585.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria,1KSMX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
SRR25158518_k127_2051604_1	479434.Sthe_3300	1.998e-183	589.0	COG0665@1|root,COG0665@2|Bacteria,2G86Q@200795|Chloroflexi,27Y37@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_2051604_7	1172185.KB911517_gene1784	2.347e-25	112.0	COG3450@1|root,COG3450@2|Bacteria,2HT6E@201174|Actinobacteria,4G55Y@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
SRR25158518_k127_2051604_4	861299.J421_1051	3.477e-73	260.0	COG3910@1|root,COG3910@2|Bacteria,1ZV0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
SRR25158518_k127_2051604_5	367299.JOEE01000002_gene2222	4.414e-59	211.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4FGDH@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRR25158518_k127_2051604_8	469383.Cwoe_3115	2.625e-11	72.0	COG2199@1|root,COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3706@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5
SRR25158518_k127_2051604_9	43354.JOIJ01000001_gene396	9.471e-11	76.0	COG3147@1|root,COG3147@2|Bacteria,2GYC2@201174|Actinobacteria,4ECZ4@85010|Pseudonocardiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2051604_6	1121946.AUAX01000023_gene4167	3.994e-38	145.0	COG2114@1|root,COG2114@2|Bacteria,2IQEQ@201174|Actinobacteria,4DFDP@85008|Micromonosporales	201174|Actinobacteria	T	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158518_k127_2051604_2	543632.JOJL01000001_gene7876	1.368e-158	523.0	COG2909@1|root,COG2909@2|Bacteria,2IBVA@201174|Actinobacteria,4DM2F@85008|Micromonosporales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158518_k127_2059163_0	1382356.JQMP01000003_gene1359	7.647e-87	311.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158518_k127_2059163_2	406124.ACPC01000019_gene2979	4.901e-10	72.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8
SRR25158518_k127_2059163_1	649638.Trad_1462	3.635e-69	254.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158518_k127_2060787_1	1385518.N798_13245	5.197e-15	88.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158518_k127_2060787_2	420324.KI911943_gene5274	1.068e-10	69.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria,1JV56@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2060787_0	1120934.KB894404_gene718	6.965e-76	263.0	COG1878@1|root,COG1878@2|Bacteria,2I66K@201174|Actinobacteria,4E76K@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158518_k127_2063190_5	1382306.JNIM01000001_gene42	1.11e-06	51.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158518_k127_2063190_1	1120936.KB907211_gene142	2.566e-54	193.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,4EJ01@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158518_k127_2063190_0	1382306.JNIM01000001_gene41	1.26e-122	412.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158518_k127_2063190_2	1392502.JNIO01000008_gene2910	3.128e-26	114.0	COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,4H4TQ@909932|Negativicutes	909932|Negativicutes	S	Protein of unknown function (DUF1290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1290
SRR25158518_k127_2063190_4	1033730.CAHG01000016_gene438	7.156e-07	60.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4DRPK@85009|Propionibacteriales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158518_k127_2063190_3	324602.Caur_0751	5.201e-07	52.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,3750N@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158518_k127_2065202_0	525904.Tter_1815	1.899e-75	259.0	COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158518_k127_2065202_1	1111479.AXAR01000016_gene3061	3.518e-53	195.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,27845@186823|Alicyclobacillaceae	91061|Bacilli	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158518_k127_2074879_5	1382306.JNIM01000001_gene2395	1.878e-37	148.0	COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DoxX family protein	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158518_k127_2074879_0	1128421.JAGA01000001_gene2088	2.206e-198	628.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2NPCW@2323|unclassified Bacteria	2|Bacteria	PQ	Multicopper oxidase	nirK	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,Cytochrom_C,Cytochrome_CBB3
SRR25158518_k127_2074879_9	1906.SFRA_23625	1.946e-14	86.0	COG2132@1|root,COG2132@2|Bacteria,2GPUP@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158518_k127_2074879_8	1090320.KB900605_gene3264	6.133e-17	87.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2UAVK@28211|Alphaproteobacteria,2K421@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158518_k127_2074879_3	246194.CHY_2564	2.971e-70	252.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,42F2N@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
SRR25158518_k127_2074879_2	1382306.JNIM01000001_gene530	2.151e-111	371.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158518_k127_2074879_1	1120973.AQXL01000111_gene924	1.556e-169	559.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,4HDVV@91061|Bacilli,2799W@186823|Alicyclobacillaceae	91061|Bacilli	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158518_k127_2074879_4	1121472.AQWN01000008_gene1985	5.67e-57	211.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,261MH@186807|Peptococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158518_k127_2074879_6	768706.Desor_5481	9.236e-33	140.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,260Y7@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158518_k127_2074879_10	392500.Swoo_1209	2.706e-06	60.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1PPHF@1224|Proteobacteria,1RYDI@1236|Gammaproteobacteria,2QAYG@267890|Shewanellaceae	1236|Gammaproteobacteria	KU	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
SRR25158518_k127_2074879_7	379066.GAU_0527	9.953e-24	108.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2080332_1	498761.HM1_2746	1.597e-93	316.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia	186801|Clostridia	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158518_k127_2080332_0	684949.ATTJ01000001_gene2189	3.965e-243	760.0	COG4799@1|root,COG4799@2|Bacteria,1WI9K@1297|Deinococcus-Thermus	2|Bacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158518_k127_2080332_2	324602.Caur_3434	1.968e-18	101.0	COG3630@1|root,COG3630@2|Bacteria	2|Bacteria	C	sodium ion export across plasma membrane	oadG	GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234	4.1.1.3	ko:K01573	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_gamma
SRR25158518_k127_2091329_0	404589.Anae109_0501	3.944e-203	648.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QJP@68525|delta/epsilon subdivisions,2WMET@28221|Deltaproteobacteria,2YVF6@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM multicopper oxidase type 2	ompC	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_2
SRR25158518_k127_2091329_3	292415.Tbd_1767	2.191e-118	393.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,1KRST@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158518_k127_2091329_10	1255043.TVNIR_3137	6.293e-33	139.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,1S61K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD)	lsrG	GO:0002952,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016853,GO:0044424,GO:0044444,GO:0044464,GO:0055114	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
SRR25158518_k127_2091329_13	1048339.KB913029_gene1934	2.731e-11	70.0	COG4747@1|root,COG4747@2|Bacteria,2GZWK@201174|Actinobacteria	201174|Actinobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2091329_1	1463887.KL589953_gene107	2.372e-185	594.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria	201174|Actinobacteria	F	Dihydropyrimidinase	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158518_k127_2091329_12	643648.Slip_1472	1.521e-16	91.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,42K31@68298|Syntrophomonadaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158518_k127_2091329_9	929712.KI912613_gene3645	1.023e-39	159.0	COG3217@1|root,COG3217@2|Bacteria,2GND9@201174|Actinobacteria,4CS20@84995|Rubrobacteria	84995|Rubrobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MOSC_N
SRR25158518_k127_2091329_6	1122939.ATUD01000001_gene196	7.788e-67	259.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria	201174|Actinobacteria	I	phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158518_k127_2091329_2	1122939.ATUD01000001_gene197	4.524e-159	546.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4CSU8@84995|Rubrobacteria	84995|Rubrobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
SRR25158518_k127_2091329_11	648885.KB316283_gene4526	5.665e-30	138.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,2U30S@28211|Alphaproteobacteria,1JQS5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158518_k127_2091329_7	443906.CMM_2884	1.274e-64	248.0	COG0382@1|root,COG0382@2|Bacteria,2GKJ2@201174|Actinobacteria,4FKV3@85023|Microbacteriaceae	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	-	-	ko:K20616	-	-	-	-	ko00000	-	-	-	UbiA
SRR25158518_k127_2091329_15	710111.FraQA3DRAFT_6449	0.0005938	46.0	2E9MI@1|root,333U6@2|Bacteria,2IMX9@201174|Actinobacteria,4ETA1@85013|Frankiales	201174|Actinobacteria	S	lycopene cyclase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2091329_14	1151122.AQYD01000005_gene3671	3.362e-07	56.0	COG3266@1|root,COG3266@2|Bacteria,2GQFT@201174|Actinobacteria,4FQ7G@85023|Microbacteriaceae	201174|Actinobacteria	S	lycopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2091329_4	485913.Krac_11396	2.526e-115	384.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2091329_8	33876.JNXY01000014_gene3929	4.879e-54	207.0	COG0438@1|root,COG0438@2|Bacteria,2IN8Y@201174|Actinobacteria,4D9G5@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
SRR25158518_k127_2091329_5	935839.JAGJ01000010_gene395	4.326e-92	304.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158518_k127_2092933_2	103690.17129740	1.208e-51	203.0	COG0076@1|root,COG0076@2|Bacteria,1G3F8@1117|Cyanobacteria,1HP30@1161|Nostocales	1117|Cyanobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86	ko:K01580,ko:K01593,ko:K13745	ko00250,ko00260,ko00350,ko00360,ko00380,ko00410,ko00430,ko00650,ko00901,ko00950,ko00965,ko01100,ko01110,ko01120,ko02024,ko04726,ko04727,ko04728,ko04940,ko05030,ko05031,ko05034,map00250,map00260,map00350,map00360,map00380,map00410,map00430,map00650,map00901,map00950,map00965,map01100,map01110,map01120,map02024,map04726,map04727,map04728,map04940,map05030,map05031,map05034	M00027,M00037,M00042	R00261,R00489,R00685,R00699,R00736,R01682,R02080,R02466,R02701,R04909,R07650	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158518_k127_2092933_5	1382306.JNIM01000001_gene4133	3.697e-21	109.0	COG0543@1|root,COG0543@2|Bacteria,2G75X@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
SRR25158518_k127_2092933_1	1382306.JNIM01000001_gene1565	2.32e-69	264.0	COG0167@1|root,COG0167@2|Bacteria,2G6RH@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158518_k127_2092933_8	1121085.AUCI01000010_gene461	2.694e-05	57.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,4HNXQ@91061|Bacilli,1ZIYS@1386|Bacillus	91061|Bacilli	S	Membrane	ysdA	-	-	-	-	-	-	-	-	-	-	-	DUF1294
SRR25158518_k127_2092933_0	391613.RTM1035_00965	2.672e-113	385.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria,46RHH@74030|Roseovarius	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158518_k127_2092933_3	479434.Sthe_0937	2.215e-44	170.0	COG0461@1|root,COG0461@2|Bacteria,2G6RG@200795|Chloroflexi,27YBT@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158518_k127_2092933_4	1128421.JAGA01000001_gene2460	2.601e-31	136.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158518_k127_2092933_7	880071.Fleli_1326	6.032e-10	72.0	COG1612@1|root,COG1612@2|Bacteria,4NEBR@976|Bacteroidetes,47JI1@768503|Cytophagia	976|Bacteroidetes	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
SRR25158518_k127_2094533_1	485913.Krac_8721	6.505e-102	346.0	COG0372@1|root,COG0372@2|Bacteria,2G7NR@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158518_k127_2094533_10	1121943.KB899990_gene3594	5.943e-11	69.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,1XMJZ@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158518_k127_2094533_6	1122138.AQUZ01000019_gene8185	1.046e-33	141.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4DQUJ@85009|Propionibacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158518_k127_2094533_5	936572.HMPREF1148_2057	4.739e-38	164.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,4H1V5@909932|Negativicutes	909932|Negativicutes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158518_k127_2094533_4	1370125.AUWT01000016_gene2511	4.219e-59	212.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,237WW@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_2094533_8	479433.Caci_1031	3.822e-16	87.0	2EBG5@1|root,335GQ@2|Bacteria,2GRUT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2094533_3	67267.JNXT01000036_gene3213	1.924e-68	248.0	COG3409@1|root,COG3409@2|Bacteria,2I9HW@201174|Actinobacteria	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,PG_binding_1
SRR25158518_k127_2094533_2	443255.SCLAV_0367	4.181e-80	292.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_2094533_0	1120936.KB907208_gene1227	1.142e-107	365.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4EI41@85012|Streptosporangiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158518_k127_2094533_7	1968.JOEV01000021_gene5853	3.567e-29	126.0	COG1357@1|root,COG1357@2|Bacteria,2GK0E@201174|Actinobacteria	201174|Actinobacteria	E	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158518_k127_2094533_9	1304872.JAGC01000003_gene2641	1.326e-15	81.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2MAEX@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIGRFAM 6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158518_k127_2095588_2	521011.Mpal_1285	7.03e-16	83.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,GSDH
SRR25158518_k127_2095588_0	1134445.AJJM01000105_gene3896	5.602e-127	440.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158518_k127_2095588_1	483219.LILAB_24905	6.154e-44	172.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,FR47
SRR25158518_k127_2095588_3	1382356.JQMP01000003_gene1723	2.943e-14	76.0	COG1853@1|root,COG1853@2|Bacteria,2G9BM@200795|Chloroflexi,27Z20@189775|Thermomicrobia	189775|Thermomicrobia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158518_k127_2100385_0	1128421.JAGA01000002_gene1560	1.057e-189	606.0	COG0119@1|root,COG0119@2|Bacteria,2NNVW@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158518_k127_2101833_6	1122994.AUFR01000020_gene269	1.277e-48	176.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158518_k127_2101833_3	1035308.AQYY01000001_gene3069	9.07e-102	349.0	COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,24IHQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158518_k127_2101833_5	543632.JOJL01000004_gene4116	1.88e-52	203.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2101833_0	1123322.KB904634_gene2428	4.377e-231	731.0	COG0491@1|root,COG0491@2|Bacteria,2IBAX@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158518_k127_2101833_2	749927.AMED_3244	5.22e-112	378.0	COG1653@1|root,COG1653@2|Bacteria,2I6SJ@201174|Actinobacteria,4DYE6@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158518_k127_2101833_1	1150864.MILUP08_45150	2.932e-118	387.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4DBFS@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158518_k127_2101833_4	1150864.MILUP08_45148	9.191e-98	342.0	COG0395@1|root,COG0395@2|Bacteria,2GJNJ@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158518_k127_2103401_3	106370.Francci3_3984	2.177e-31	128.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4ET46@85013|Frankiales	201174|Actinobacteria	H	DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR25158518_k127_2103401_4	1123322.KB904726_gene2119	1.927e-29	128.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158518_k127_2103401_1	479434.Sthe_3084	8.275e-65	234.0	COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,27YA5@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
SRR25158518_k127_2103401_0	1131814.JAFO01000001_gene1156	0.0	1508.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3EXXE@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158518_k127_2103401_5	42256.RradSPS_0338	5.673e-26	114.0	COG0531@1|root,COG0531@2|Bacteria,2GMTD@201174|Actinobacteria,4CQQ1@84995|Rubrobacteria	84995|Rubrobacteria	E	COG COG0531 Amino acid transporters Amino acid transport and metabolism	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158518_k127_2141025_0	379066.GAU_2878	2.817e-126	417.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria	2|Bacteria	P	solute:proton antiporter activity	ybaL	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR25158518_k127_2141025_1	526225.Gobs_2285	1.615e-95	349.0	COG1204@1|root,COG1204@2|Bacteria	2|Bacteria	L	response to ionizing radiation	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	DEAD,HIRAN,Helicase_C,SUV3_C
SRR25158518_k127_2141025_5	504728.K649_04355	2.212e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,1WND2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158518_k127_2141025_12	1179773.BN6_29050	3.532e-06	55.0	COG5637@1|root,COG5637@2|Bacteria,2IKRQ@201174|Actinobacteria,4E5NM@85010|Pseudonocardiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158518_k127_2141025_6	309800.C498_13539	1.143e-39	154.0	COG3358@1|root,arCOG04570@2157|Archaea,2XX3J@28890|Euryarchaeota,23VM5@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158518_k127_2141025_11	1028307.EAE_22060	3.461e-06	59.0	COG0477@1|root,COG2814@2|Bacteria,1N1R8@1224|Proteobacteria,1RQPQ@1236|Gammaproteobacteria,3X315@547|Enterobacter	1236|Gammaproteobacteria	EGP	Sugar (and other) transporter	ydhC_1	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_2141025_2	369723.Strop_0502	1.199e-47	187.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,4DF4Z@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158518_k127_2141025_10	1265310.CCBD010000059_gene1326	1.742e-08	63.0	2B8K4@1|root,321VD@2|Bacteria,2H619@201174|Actinobacteria,23E0B@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2141025_4	675635.Psed_0313	2.154e-44	167.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4E4PD@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158518_k127_2141025_3	469371.Tbis_1015	2.332e-46	178.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4E53R@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158518_k127_2141025_8	1120934.KB894423_gene2695	4.34e-36	143.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4E4JT@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158518_k127_2141025_9	1356854.N007_15750	8.172e-13	81.0	COG3409@1|root,COG3858@1|root,COG3409@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4IQ9G@91061|Bacilli,27A01@186823|Alicyclobacillaceae	91061|Bacilli	M	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM
SRR25158518_k127_2141025_7	1331060.RLDS_22310	2.482e-39	149.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2K0VT@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158518_k127_214814_2	1463825.JNXC01000031_gene1589	2.509e-54	200.0	COG0673@1|root,COG0673@2|Bacteria,2IFZE@201174|Actinobacteria,4ECGC@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,ox_reductase_C
SRR25158518_k127_214814_0	1254432.SCE1572_36930	1.806e-233	745.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2YX9E@29|Myxococcales	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
SRR25158518_k127_214814_6	515635.Dtur_0211	1.067e-17	96.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019,ko:K13292	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158518_k127_214814_3	765420.OSCT_1961	1.226e-41	164.0	COG1279@1|root,COG1279@2|Bacteria	2|Bacteria	S	arginine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158518_k127_214814_1	1131813.AQVT01000001_gene504	3.148e-184	605.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,1JQVU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158518_k127_214814_4	1122609.AUGT01000022_gene731	6.588e-34	150.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4DN8K@85009|Propionibacteriales	201174|Actinobacteria	V	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158518_k127_214814_5	926550.CLDAP_04280	1.03e-27	125.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158518_k127_2166883_1	264732.Moth_1943	5.239e-123	410.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,42EUH@68295|Thermoanaerobacterales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158518_k127_2166883_2	292459.STH1921	4.939e-46	170.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158518_k127_2166883_0	446462.Amir_5660	9.206e-125	411.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4DXZ6@85010|Pseudonocardiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158518_k127_2166883_3	468556.AQYG01000045_gene1941	8.507e-15	76.0	COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,4GAV8@85026|Gordoniaceae	201174|Actinobacteria	L	NUDIX domain	mutT4	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158518_k127_2181968_0	1382306.JNIM01000001_gene426	6.47e-116	385.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158518_k127_2181968_1	861360.AARI_14080	1.184e-66	250.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Beta_helix,Hepar_II_III,Hepar_II_III_N,Pectate_lyase_3
SRR25158518_k127_2181968_2	626887.J057_15510	3.135e-33	140.0	COG0543@1|root,COG0543@2|Bacteria,1QTSK@1224|Proteobacteria	1224|Proteobacteria	CH	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRR25158518_k127_218455_2	743525.TSC_c01640	4.271e-31	129.0	COG1387@1|root,COG1387@2|Bacteria,1WIU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	TIGRFAM histidinol phosphate phosphatase HisJ family	-	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP,PHP_C
SRR25158518_k127_218455_1	357808.RoseRS_3810	2.458e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,375U2@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SRR25158518_k127_218455_0	2074.JNYD01000022_gene1502	8.239e-39	155.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria,4DYEQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Beta-lactamase	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158518_k127_218455_3	1278073.MYSTI_02484	6.63e-29	134.0	COG4346@1|root,COG4346@2|Bacteria,1QHX0@1224|Proteobacteria	1224|Proteobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
SRR25158518_k127_2189556_0	537013.CLOSTMETH_00057	3.154e-85	295.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
SRR25158518_k127_2189556_1	889378.Spiaf_1752	8.495e-05	50.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158518_k127_2200556_6	1173020.Cha6605_4223	9.113e-42	170.0	COG3881@1|root,COG3881@2|Bacteria,1G23A@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SRR25158518_k127_2200556_2	1380390.JIAT01000001_gene5080	2.614e-96	339.0	COG0665@1|root,COG0665@2|Bacteria,2IEZA@201174|Actinobacteria,4CRMC@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_2200556_8	1246995.AFR_34195	3.754e-28	123.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DD9T@85008|Micromonosporales	201174|Actinobacteria	K	a CheY-like receiver domain and	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158518_k127_2200556_0	1095769.CAHF01000006_gene1863	5.635e-225	731.0	COG0463@1|root,COG0463@2|Bacteria,1QV5U@1224|Proteobacteria,2W2UZ@28216|Betaproteobacteria,4795X@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158518_k127_2200556_1	1335760.ASTG01000019_gene2731	5.916e-164	524.0	COG0438@1|root,COG0562@1|root,COG0438@2|Bacteria,COG0562@2|Bacteria,1MV4H@1224|Proteobacteria,2TTP4@28211|Alphaproteobacteria,2K2QF@204457|Sphingomonadales	204457|Sphingomonadales	M	UDP-galactopyranose mutase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,Glyco_trans_1_4,NAD_binding_8
SRR25158518_k127_2200556_3	1121106.JQKB01000047_gene3993	5.419e-82	297.0	COG2723@1|root,COG2723@2|Bacteria,1MWU7@1224|Proteobacteria,2TT4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
SRR25158518_k127_2200556_5	593750.Metfor_0988	1.568e-51	194.0	COG1226@1|root,arCOG01964@2157|Archaea,2Y19J@28890|Euryarchaeota,2NADN@224756|Methanomicrobia	224756|Methanomicrobia	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158518_k127_2200556_9	693746.OBV_10370	1.135e-05	57.0	COG1141@1|root,COG1141@2|Bacteria,1UQ9Z@1239|Firmicutes,2580A@186801|Clostridia,2N8NF@216572|Oscillospiraceae	186801|Clostridia	C	Divergent 4Fe-4S mono-cluster	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
SRR25158518_k127_2200556_4	529884.Rhola_00013670	1.22e-67	250.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4FPIW@85023|Microbacteriaceae	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158518_k127_2200556_7	1499967.BAYZ01000010_gene5201	1.402e-39	153.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158518_k127_2203412_3	1336208.JADY01000009_gene2593	1.257e-21	107.0	COG2267@1|root,COG2267@2|Bacteria,1MYEX@1224|Proteobacteria,2UDZD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158518_k127_2203412_0	383372.Rcas_0007	3.26e-151	501.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi,376BY@32061|Chloroflexia	32061|Chloroflexia	L	Helix-hairpin-helix DNA-binding, class 1	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158518_k127_2203412_4	28444.JODQ01000013_gene2921	9.907e-16	87.0	2E9BC@1|root,333J8@2|Bacteria,2GQX9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2203412_1	1266909.AUAG01000038_gene1598	7.334e-32	144.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE4,GGDEF,PAS_9
SRR25158518_k127_2203412_2	649747.HMPREF0083_04990	1.57e-30	127.0	COG2199@1|root,COG3706@2|Bacteria,1UMJJ@1239|Firmicutes,4ITX3@91061|Bacilli,277FC@186822|Paenibacillaceae	91061|Bacilli	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SRR25158518_k127_2203991_2	869210.Marky_0686	7.894e-55	201.0	COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158518_k127_2203991_0	661478.OP10G_0129	1.159e-138	445.0	COG0005@1|root,COG0005@2|Bacteria	2|Bacteria	F	purine-nucleoside phosphorylase activity	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158518_k127_2203991_5	70448.Q018C9	2.155e-29	132.0	COG0483@1|root,KOG2951@2759|Eukaryota,37M8T@33090|Viridiplantae,34HQD@3041|Chlorophyta	3041|Chlorophyta	G	Inositol-1-monophosphatase	-	-	3.1.3.25,3.1.3.93	ko:K10047	ko00053,ko00562,ko01100,ko01110,ko04070,map00053,map00562,map01100,map01110,map04070	M00114,M00131	R01185,R01186,R01187,R07674	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iRC1080.CRv4_Au5_s13_g5028_t1	Inositol_P
SRR25158518_k127_2203991_1	391625.PPSIR1_15265	9.052e-89	312.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158518_k127_2203991_3	1229780.BN381_60027	2.5e-54	204.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,3UWWF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158518_k127_2203991_4	479434.Sthe_1941	3.682e-53	196.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_2204982_13	1449976.KALB_6922	8.686e-16	80.0	COG2197@1|root,COG2197@2|Bacteria,2GNAU@201174|Actinobacteria,4DYJ4@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158518_k127_2204982_0	1348663.KCH_12260	0.0	1716.0	COG2132@1|root,COG2132@2|Bacteria,2ICI4@201174|Actinobacteria	201174|Actinobacteria	Q	Fibronectin type iii domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
SRR25158518_k127_2204982_1	1172188.KB911820_gene2633	0.0	1026.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FG4H@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158518_k127_2204982_2	269799.Gmet_2154	1.988e-164	534.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42MPR@68525|delta/epsilon subdivisions,2WNM3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158518_k127_2204982_5	512565.AMIS_17330	5.23e-70	269.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria,4DD8N@85008|Micromonosporales	201174|Actinobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158518_k127_2204982_8	1110697.NCAST_33_00880	9.812e-53	197.0	COG0463@1|root,COG0463@2|Bacteria,2HHC5@201174|Actinobacteria,4FXC4@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158518_k127_2204982_7	561175.KB894094_gene2037	9.506e-66	242.0	COG2124@1|root,COG2124@2|Bacteria,2IAJ4@201174|Actinobacteria,4ENBE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158518_k127_2204982_4	471852.Tcur_2088	5.985e-71	270.0	COG0318@1|root,COG1215@1|root,COG0318@2|Bacteria,COG1215@2|Bacteria,2IB3B@201174|Actinobacteria,4EMTB@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158518_k127_2204982_9	471852.Tcur_3650	4.26e-46	182.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4EJYH@85012|Streptosporangiales	201174|Actinobacteria	GM	Male sterility protein	-	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SRR25158518_k127_2204982_19	452652.KSE_01660	4.21e-05	53.0	2CFSP@1|root,31CCI@2|Bacteria,2IFDM@201174|Actinobacteria,2M3XS@2063|Kitasatospora	201174|Actinobacteria	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
SRR25158518_k127_2204982_3	1121033.AUCF01000005_gene5165	6.972e-89	298.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,2JQN7@204441|Rhodospirillales	204441|Rhodospirillales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158518_k127_2204982_11	552531.BIF_02222	2.443e-38	150.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158518_k127_2204982_15	765910.MARPU_02840	1.441e-11	76.0	COG1704@1|root,COG1704@2|Bacteria,1RDUH@1224|Proteobacteria,1S2KR@1236|Gammaproteobacteria,1WY4K@135613|Chromatiales	135613|Chromatiales	S	E3 Ubiquitin ligase	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
SRR25158518_k127_2204982_16	1517682.HW49_05715	3.82e-11	71.0	COG1983@1|root,COG3595@1|root,COG1983@2|Bacteria,COG3595@2|Bacteria,4NG3T@976|Bacteroidetes,2FPZX@200643|Bacteroidia,22XZS@171551|Porphyromonadaceae	976|Bacteroidetes	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
SRR25158518_k127_2204982_17	138119.DSY4125	7.704e-06	57.0	2DPQR@1|root,3330J@2|Bacteria,1VF83@1239|Firmicutes,25EKT@186801|Clostridia,2645C@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2204982_18	1128421.JAGA01000002_gene1097	2.268e-05	54.0	COG0762@1|root,COG0762@2|Bacteria,2NRP0@2323|unclassified Bacteria	2|Bacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
SRR25158518_k127_2204982_12	65393.PCC7424_1172	3.472e-26	118.0	COG0204@1|root,COG0204@2|Bacteria,1G1AK@1117|Cyanobacteria,3KH6W@43988|Cyanothece	1117|Cyanobacteria	I	phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158518_k127_2204982_14	1440053.JOEI01000011_gene4767	4.205e-15	86.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria	201174|Actinobacteria	H	Pfam UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158518_k127_2204982_10	690585.JNNU01000017_gene323	1.998e-43	171.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,4B7NP@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158518_k127_2204982_6	585531.HMPREF0063_10664	7.857e-69	242.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DP0V@85009|Propionibacteriales	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158518_k127_2205522_2	264732.Moth_0971	5.271e-39	151.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,42GJ8@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158518_k127_2205522_0	1122611.KB903949_gene6599	1.678e-103	344.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4EIXN@85012|Streptosporangiales	201174|Actinobacteria	S	Phenazine biosynthesis-like protein	phzF	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158518_k127_2205522_1	395961.Cyan7425_1166	7.267e-59	213.0	COG0164@1|root,COG0164@2|Bacteria,1G507@1117|Cyanobacteria,3KHNX@43988|Cyanothece	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158518_k127_2205522_3	1074488.AGBX01000005_gene2689	4.488e-11	68.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4FD67@85020|Dermabacteraceae	201174|Actinobacteria	L	Uncharacterised protein family UPF0102	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158518_k127_2206138_2	697281.Mahau_2191	5.683e-85	285.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F44@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158518_k127_2206138_5	1122201.AUAZ01000001_gene2338	2.126e-74	279.0	COG2304@1|root,COG2304@2|Bacteria,1QU09@1224|Proteobacteria,1T39R@1236|Gammaproteobacteria,46DBS@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
SRR25158518_k127_2206138_4	298654.FraEuI1c_4033	2.188e-76	269.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_2206138_9	1324957.K933_02381	3.294e-11	76.0	arCOG08617@1|root,arCOG08617@2157|Archaea,2XW39@28890|Euryarchaeota,23SYN@183963|Halobacteria	183963|Halobacteria	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158518_k127_2206138_0	656024.FsymDg_0919	1.241e-146	487.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4ES82@85013|Frankiales	201174|Actinobacteria	L	PFAM UvrD REP helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
SRR25158518_k127_2206138_1	1254432.SCE1572_05170	3.736e-133	451.0	COG2334@1|root,COG2334@2|Bacteria,1R27Y@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158518_k127_2206138_7	28444.JODQ01000010_gene3137	1.444e-31	142.0	COG0454@1|root,COG0454@2|Bacteria,2II6H@201174|Actinobacteria,4EQZX@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
SRR25158518_k127_2206138_6	2002.JOEQ01000074_gene6426	5.06e-56	216.0	COG1917@1|root,COG1917@2|Bacteria,2IIQD@201174|Actinobacteria,4EJQH@85012|Streptosporangiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158518_k127_2206138_3	298655.KI912267_gene6923	1.645e-79	275.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4EU63@85013|Frankiales	201174|Actinobacteria	C	aldo keto reductase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158518_k127_2206907_0	292459.STH3193	1.285e-251	784.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158518_k127_2206907_2	479435.Kfla_7070	3.322e-05	54.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria,4DQNZ@85009|Propionibacteriales	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_2206907_1	1121472.AQWN01000007_gene1143	1.828e-59	213.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,260ZG@186807|Peptococcaceae	186801|Clostridia	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158518_k127_2209230_0	635013.TherJR_2422	3.429e-84	295.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,2610I@186807|Peptococcaceae	186801|Clostridia	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158518_k127_2209230_1	1313172.YM304_23950	7.057e-20	99.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CN8G@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
SRR25158518_k127_2209230_2	509191.AEDB02000099_gene4048	0.0002154	52.0	COG2373@1|root,COG2373@2|Bacteria,1TRBD@1239|Firmicutes,24CW4@186801|Clostridia,3WP0X@541000|Ruminococcaceae	186801|Clostridia	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N_2,Big_5,zf-HC2
SRR25158518_k127_2218789_5	1125699.HMPREF9194_01562	2.283e-15	78.0	COG0443@1|root,COG0443@2|Bacteria,2J5I0@203691|Spirochaetes	203691|Spirochaetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158518_k127_2218789_3	479434.Sthe_0715	6.212e-28	120.0	COG0576@1|root,COG0576@2|Bacteria,2G6WR@200795|Chloroflexi,27YDX@189775|Thermomicrobia	189775|Thermomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158518_k127_2218789_1	383372.Rcas_4390	4.76e-74	261.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
SRR25158518_k127_2218789_4	709986.Deima_1142	1.791e-22	108.0	2C4JB@1|root,337ZU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2218789_0	292459.STH3279	3.582e-110	378.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158518_k127_2218789_2	67373.JOBF01000003_gene404	6.292e-67	250.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158518_k127_2218789_7	525904.Tter_1477	8.408e-05	53.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158518_k127_2218789_6	1033740.CAEW01000016_gene2809	2.573e-12	66.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,26DW4@186818|Planococcaceae	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158518_k127_2232847_1	326424.FRAAL4104	1.925e-21	96.0	COG1304@1|root,COG1304@2|Bacteria,2IHII@201174|Actinobacteria,4EX24@85013|Frankiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158518_k127_2232847_0	1121430.JMLG01000005_gene768	3.41e-182	596.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,260BN@186807|Peptococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158518_k127_2232847_2	1381123.AYOD01000063_gene1566	2.606e-05	52.0	COG0834@1|root,COG0834@2|Bacteria,1N6H5@1224|Proteobacteria,2U5FP@28211|Alphaproteobacteria,43I69@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158518_k127_2239981_1	1108045.GORHZ_125_00130	6.184e-36	143.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4GCIC@85026|Gordoniaceae	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SRR25158518_k127_2239981_0	1345697.M493_11945	5.218e-40	155.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,1WFXX@129337|Geobacillus	91061|Bacilli	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
SRR25158518_k127_2239981_2	351607.Acel_2026	2.24e-23	113.0	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4ESJ5@85013|Frankiales	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158518_k127_2239981_3	345341.KUTG_04395	1.978e-17	90.0	COG0457@1|root,COG0457@2|Bacteria,2I3MN@201174|Actinobacteria,4E4BA@85010|Pseudonocardiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158518_k127_2239981_4	1215092.PA6_028_01060	4.319e-06	59.0	COG0477@1|root,COG2814@2|Bacteria,1R8UR@1224|Proteobacteria,1T1TJ@1236|Gammaproteobacteria,1YIDI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	EGP	Sugar (and other) transporter	ycaD_1	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158518_k127_2240787_1	479435.Kfla_4142	1.042e-112	372.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4DPGH@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158518_k127_2240787_2	1042376.AFPK01000068_gene476	3.934e-05	46.0	2EHBZ@1|root,33B3U@2|Bacteria,4NZK3@976|Bacteroidetes,1I71Q@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2240787_0	357808.RoseRS_0219	6.983e-115	397.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi,374WV@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158518_k127_2246518_0	383372.Rcas_0866	2.997e-187	589.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi,376SB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158518_k127_2246518_3	1047013.AQSP01000134_gene1338	1.18e-99	365.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
SRR25158518_k127_2246518_2	1304874.JAFY01000002_gene574	9.537e-101	347.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
SRR25158518_k127_2246518_4	1089553.Tph_c27670	5.097e-53	211.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
SRR25158518_k127_2246518_1	96561.Dole_1111	6.993e-153	497.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
SRR25158518_k127_2247699_1	1382306.JNIM01000001_gene4155	2.886e-70	241.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158518_k127_2247699_3	255470.cbdbA944	5.479e-12	70.0	29WVC@1|root,30IH0@2|Bacteria,2G9KW@200795|Chloroflexi,34DPM@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2247699_2	1227457.C451_15468	4.699e-66	238.0	COG2820@1|root,arCOG01324@2157|Archaea,2XSWN@28890|Euryarchaeota,23SKE@183963|Halobacteria	183963|Halobacteria	F	Uridine phosphorylase	udp2	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158518_k127_2247699_4	309807.SRU_0873	1.164e-07	66.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1FJWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SRR25158518_k127_2247699_0	1380354.JIAN01000010_gene3061	2.542e-195	662.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4F0IU@85016|Cellulomonadaceae	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158518_k127_2248136_3	313624.NSP_33190	4.387e-10	72.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
SRR25158518_k127_2248136_2	525904.Tter_0442	2.531e-32	142.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,PilZ,Response_reg
SRR25158518_k127_2248136_0	1242864.D187_009388	3.975e-45	170.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,42P3W@68525|delta/epsilon subdivisions,2WNCT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158518_k127_2248136_1	1280390.CBQR020000018_gene391	5.219e-36	138.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,26QK6@186822|Paenibacillaceae	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
SRR25158518_k127_225287_2	1156937.MFUM_550025	4.43e-13	79.0	COG0589@1|root,COG0589@2|Bacteria,46WHB@74201|Verrucomicrobia,37GYA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158518_k127_225287_1	1957.JODX01000008_gene2321	6.885e-17	91.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158518_k127_225287_0	1128421.JAGA01000001_gene2186	8.972e-28	122.0	COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria	2|Bacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158518_k127_2263996_2	1177594.MIC448_2190008	1.15e-27	117.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K03090,ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158518_k127_2263996_0	298654.FraEuI1c_4940	2.842e-153	499.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4EU9R@85013|Frankiales	201174|Actinobacteria	Q	NAD(P)-binding Rossmann-like domain	p	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158518_k127_2263996_3	743718.Isova_1708	4.751e-06	59.0	COG4585@1|root,COG4585@2|Bacteria,2IS2Y@201174|Actinobacteria,4F5RX@85017|Promicromonosporaceae	201174|Actinobacteria	T	dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158518_k127_2271207_3	266117.Rxyl_1831	2.155e-15	78.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria	201174|Actinobacteria	O	belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158518_k127_2271207_2	644283.Micau_5051	2.8e-17	91.0	COG5012@1|root,COG5012@2|Bacteria,2GKAY@201174|Actinobacteria,4DBNU@85008|Micromonosporales	201174|Actinobacteria	S	Cobalamin B12-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158518_k127_2271207_0	1521187.JPIM01000120_gene287	1.255e-217	696.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158518_k127_2271207_1	1385520.N802_11095	3.437e-27	128.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158518_k127_2274684_2	926550.CLDAP_22740	5.561e-16	78.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158518_k127_2274684_3	1032480.MLP_00120	3.487e-07	63.0	COG0515@1|root,COG0823@1|root,COG3170@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,COG3170@2|Bacteria,2GIW5@201174|Actinobacteria,4DUI1@85009|Propionibacteriales	201174|Actinobacteria	KLTU	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SRR25158518_k127_2274684_0	1380347.JNII01000011_gene830	4.398e-243	764.0	COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4ERTX@85013|Frankiales	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158518_k127_2274684_1	526227.Mesil_0382	8.488e-226	719.0	COG1505@1|root,COG1505@2|Bacteria,1WMDW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158518_k127_2298258_4	1122933.JNIY01000003_gene92	4.862e-79	279.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4F24H@85016|Cellulomonadaceae	201174|Actinobacteria	P	Sulfate permease family	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158518_k127_2298258_7	368407.Memar_2102	3.528e-50	195.0	COG0038@1|root,arCOG02569@2157|Archaea,2Y26D@28890|Euryarchaeota	28890|Euryarchaeota	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR25158518_k127_2298258_8	1151118.KB895784_gene3014	4.089e-38	156.0	COG3591@1|root,COG3591@2|Bacteria,2GJVS@201174|Actinobacteria,1WA3M@1268|Micrococcaceae	201174|Actinobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2298258_5	479435.Kfla_0277	1.412e-74	262.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DQZN@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2298258_3	1298863.AUEP01000019_gene3529	2.676e-91	326.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria,4DT5X@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158518_k127_2298258_9	420324.KI911970_gene1590	8.797e-12	77.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,1JTF9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	CAP,HemolysinCabind
SRR25158518_k127_2298258_2	42256.RradSPS_0763	8.967e-94	316.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria,4CT8V@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158518_k127_2298258_1	1122933.JNIY01000012_gene1317	3.704e-111	374.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4F31P@85016|Cellulomonadaceae	201174|Actinobacteria	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_2298258_0	1125971.ASJB01000099_gene2288	7.313e-112	372.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4E1YQ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_2298258_6	1121272.KB903290_gene4687	1.864e-71	258.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158518_k127_2298258_10	981369.JQMJ01000004_gene449	3.581e-07	63.0	COG0842@1|root,COG0842@2|Bacteria,2HNB6@201174|Actinobacteria,2NHZ8@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR25158518_k127_2303078_0	383372.Rcas_1849	7.843e-61	221.0	COG1609@1|root,COG1609@2|Bacteria,2GAIK@200795|Chloroflexi,377B5@32061|Chloroflexia	32061|Chloroflexia	K	periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
SRR25158518_k127_2305727_3	1380393.JHVP01000005_gene3743	8.067e-59	221.0	COG1802@1|root,COG1802@2|Bacteria,2GJRM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158518_k127_2305727_0	1382306.JNIM01000001_gene3234	2.913e-220	704.0	COG3848@1|root,COG3848@2|Bacteria,2G8N4@200795|Chloroflexi	200795|Chloroflexi	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
SRR25158518_k127_2305727_1	477641.MODMU_2359	1.151e-70	248.0	COG1802@1|root,COG1802@2|Bacteria,2GJRM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158518_k127_2305727_2	1380393.JHVP01000005_gene3733	6.265e-68	239.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	idnO	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158518_k127_2307193_3	357808.RoseRS_1305	7.735e-14	72.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158518_k127_2307193_0	326427.Cagg_1324	1.524e-69	266.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,3754V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
SRR25158518_k127_2307193_2	404589.Anae109_2948	1.126e-18	97.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.64	ko:K00852,ko:K19517	ko00030,ko00562,ko01100,map00030,map00562,map01100	-	R01051,R02750,R07279	RC00002,RC00017,RC00078	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158518_k127_2307193_1	1242864.D187_010392	6.828e-40	165.0	COG3359@1|root,COG3359@2|Bacteria,1R5KG@1224|Proteobacteria,437YC@68525|delta/epsilon subdivisions,2X388@28221|Deltaproteobacteria,2YUT6@29|Myxococcales	28221|Deltaproteobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
SRR25158518_k127_2311557_0	999547.KI421500_gene3387	2.493e-23	109.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2TU8X@28211|Alphaproteobacteria,2827Q@191028|Leisingera	28211|Alphaproteobacteria	T	Crp-like helix-turn-helix domain	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158518_k127_2311557_1	713587.THITH_05010	1.181e-10	75.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
SRR25158518_k127_2312078_2	1040986.ATYO01000017_gene890	3.371e-39	152.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TR6X@28211|Alphaproteobacteria,43J54@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158518_k127_2312078_0	316274.Haur_2762	7.509e-150	503.0	COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi,3766I@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158518_k127_2312078_1	1111479.AXAR01000001_gene331	9.897e-68	245.0	COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,2788Y@186823|Alicyclobacillaceae	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
SRR25158518_k127_2312078_3	211165.AJLN01000040_gene6449	8.515e-20	88.0	COG3185@1|root,COG3185@2|Bacteria,1G307@1117|Cyanobacteria,1JKH1@1189|Stigonemataceae	1117|Cyanobacteria	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_4,Glyoxalase_5
SRR25158518_k127_2320843_2	397278.JOJN01000002_gene85	1.418e-85	291.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4DNFH@85009|Propionibacteriales	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158518_k127_2320843_0	1194165.CAJF01000004_gene2794	9.316e-169	542.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4FKJ1@85023|Microbacteriaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
SRR25158518_k127_2320843_1	211114.JOEF01000001_gene7037	2.016e-95	329.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4E020@85010|Pseudonocardiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158518_k127_2320843_3	103733.JNYO01000002_gene600	3.216e-47	177.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4DZQG@85010|Pseudonocardiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SRR25158518_k127_232566_0	710696.Intca_1871	6.184e-102	357.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569,ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrome_C7
SRR25158518_k127_232566_1	1121017.AUFG01000010_gene1639	4.359e-34	139.0	COG0526@1|root,COG0526@2|Bacteria,2IS1E@201174|Actinobacteria,4FJ5Y@85021|Intrasporangiaceae	201174|Actinobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158518_k127_2335684_1	40571.JOEA01000014_gene1674	7.868e-102	337.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158518_k127_2335684_0	1123023.JIAI01000020_gene2107	4.085e-131	439.0	COG3383@1|root,COG3383@2|Bacteria,2GKBP@201174|Actinobacteria,4DXFK@85010|Pseudonocardiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
SRR25158518_k127_2335684_3	1396141.BATP01000003_gene5035	3.838e-08	65.0	COG3021@1|root,COG3021@2|Bacteria	2|Bacteria	S	interspecies interaction between organisms	VPA0486	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158518_k127_2335684_2	710696.Intca_1881	5.957e-77	287.0	COG3850@1|root,COG3850@2|Bacteria,2HY2J@201174|Actinobacteria,4FJI8@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
SRR25158518_k127_233954_4	1382306.JNIM01000001_gene4120	1.729e-17	93.0	COG0558@1|root,COG0558@2|Bacteria,2G6RT@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158518_k127_233954_6	1203568.HMPREF1484_02083	1.873e-11	69.0	COG0640@1|root,COG0640@2|Bacteria,2IM0G@201174|Actinobacteria,4FD1A@85020|Dermabacteraceae	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	kmtR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SRR25158518_k127_233954_5	1380356.JNIK01000014_gene3267	3.762e-14	77.0	COG3809@1|root,COG3809@2|Bacteria,2IKNG@201174|Actinobacteria,4ET9R@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
SRR25158518_k127_233954_1	479434.Sthe_1684	4.966e-48	195.0	COG0477@1|root,COG2814@2|Bacteria,2G7PR@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_233954_2	909663.KI867149_gene3382	8.113e-45	181.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2MQ5E@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158518_k127_233954_3	309801.trd_A0739	7.343e-28	129.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158518_k127_233954_0	316067.Geob_0475	2.976e-84	291.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158518_k127_2350463_1	1521187.JPIM01000054_gene3095	0.0001668	44.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,3778H@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158518_k127_2350463_0	1408254.T458_12325	1.42e-34	145.0	COG0697@1|root,COG0697@2|Bacteria,1V3QH@1239|Firmicutes,4HDBZ@91061|Bacilli	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_2350463_2	644282.Deba_0415	0.0003208	52.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_circ_N,DUF928,LysM
SRR25158518_k127_2370508_5	189425.PGRAT_11095	1.378e-17	95.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158518_k127_2370508_3	1463845.JOIG01000008_gene3764	1.083e-41	169.0	COG0454@1|root,COG0456@2|Bacteria,2IAC7@201174|Actinobacteria	201174|Actinobacteria	K	Aminoglycoside 2'-N-acetyltransferase	aac	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_9
SRR25158518_k127_2370508_2	316274.Haur_1630	9.405e-50	183.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	yuaD	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158518_k127_2370508_4	644283.Micau_3022	2.204e-41	164.0	COG4405@1|root,COG4405@2|Bacteria,2IKQP@201174|Actinobacteria,4DEHX@85008|Micromonosporales	201174|Actinobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
SRR25158518_k127_2370508_0	500153.JOEK01000001_gene3675	9.087e-114	383.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2370508_1	365528.KB891241_gene6214	3.538e-89	312.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4EUMC@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_2370508_6	667015.Bacsa_2404	3.97e-06	49.0	COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,2FPJ4@200643|Bacteroidia,4AMQE@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158518_k127_2378070_1	479434.Sthe_2174	2.468e-17	90.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2378070_2	596154.Alide2_0660	0.0003758	51.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,4AF8Z@80864|Comamonadaceae	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SRR25158518_k127_2378070_0	526227.Mesil_1879	7.766e-70	241.0	COG2065@1|root,COG2065@2|Bacteria,1WJWR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158518_k127_2381206_2	994479.GL877880_gene3818	1.652e-74	264.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4E0QI@85010|Pseudonocardiales	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH2	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158518_k127_2381206_1	479435.Kfla_1281	9.503e-157	504.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4DPBM@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158518_k127_2381206_0	1907.SGLAU_15155	4.368e-282	904.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158518_k127_2381206_3	1502724.FF80_02580	3.889e-36	156.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,3N7V0@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR25158518_k127_2385802_0	477641.MODMU_2393	1.611e-216	685.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EUBU@85013|Frankiales	201174|Actinobacteria	C	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158518_k127_2385802_1	1415166.NONO_c58960	4.243e-133	463.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4FVX8@85025|Nocardiaceae	201174|Actinobacteria	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
SRR25158518_k127_2385802_5	279238.Saro_3040	3.706e-18	95.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,2K1WW@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
SRR25158518_k127_2385802_2	357808.RoseRS_2512	8.936e-69	246.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi,375NG@32061|Chloroflexia	32061|Chloroflexia	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158518_k127_2385802_4	512565.AMIS_5070	1.575e-61	222.0	COG2188@1|root,COG2188@2|Bacteria,2IK3E@201174|Actinobacteria,4DDPG@85008|Micromonosporales	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158518_k127_2385802_3	997346.HMPREF9374_1840	3.871e-63	231.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,27BC5@186824|Thermoactinomycetaceae	91061|Bacilli	G	Amidohydrolase family	-	-	3.5.1.25	ko:K01443,ko:K16786,ko:K16787	ko00520,ko01130,ko02010,map00520,map01130,map02010	M00582	R02059	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	Amidohydro_1
SRR25158518_k127_2399471_2	1463855.JOHV01000020_gene3024	3.749e-29	121.0	COG0600@1|root,COG0600@2|Bacteria,2HDX7@201174|Actinobacteria	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158518_k127_2399471_0	1122223.KB890688_gene1629	7.757e-93	320.0	COG1116@1|root,COG1116@2|Bacteria,1WM71@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158518_k127_2399471_1	1122175.ATXU01000011_gene1641	2.457e-46	188.0	COG0600@1|root,COG0600@2|Bacteria,2IFIB@201174|Actinobacteria,4FNJP@85023|Microbacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158518_k127_2414903_2	1150864.MILUP08_45148	4.657e-74	252.0	COG0395@1|root,COG0395@2|Bacteria,2GJNJ@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158518_k127_2414903_0	211114.JOEF01000025_gene191	2.644e-294	926.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4DYF8@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158518_k127_2414903_1	1449353.JQMQ01000005_gene5318	2.58e-233	746.0	COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria,2NI08@228398|Streptacidiphilus	201174|Actinobacteria	G	Glycosyl hydrolases family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_N
SRR25158518_k127_2430006_7	1237500.ANBA01000011_gene3645	6.045e-05	46.0	COG0842@1|root,COG0842@2|Bacteria,2I0XU@201174|Actinobacteria,4EGKP@85012|Streptosporangiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_2430006_2	1128421.JAGA01000002_gene425	1.578e-116	389.0	COG1840@1|root,COG1840@2|Bacteria,2NPYA@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158518_k127_2430006_1	266117.Rxyl_1174	1.447e-130	434.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158518_k127_2430006_3	649638.Trad_1533	8.882e-83	306.0	COG3842@1|root,COG3842@2|Bacteria,1WIBV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type spermidine putrescine transport systems, ATPase components	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158518_k127_2430006_0	1283299.AUKG01000001_gene1412	0.0	1168.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158518_k127_2430006_5	1150398.JIBJ01000014_gene2460	4.253e-19	95.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158518_k127_2430006_6	591157.SSLG_01585	1.365e-11	75.0	COG1846@1|root,COG1846@2|Bacteria,2IHYF@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158518_k127_2430006_4	697281.Mahau_2190	1.082e-50	185.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,42FRT@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158518_k127_2436636_2	621372.ACIH01000184_gene3145	7.883e-86	292.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26TPG@186822|Paenibacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158518_k127_2436636_9	1163408.UU9_09212	0.0009216	50.0	COG0662@1|root,COG0662@2|Bacteria,1N3N8@1224|Proteobacteria,1SA89@1236|Gammaproteobacteria,1XCWN@135614|Xanthomonadales	135614|Xanthomonadales	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158518_k127_2436636_1	525904.Tter_0028	3.229e-97	325.0	COG1351@1|root,COG1351@2|Bacteria,2NQ7P@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
SRR25158518_k127_2436636_3	937777.Deipe_0311	1.74e-52	206.0	COG0477@1|root,COG2814@2|Bacteria,1WIWD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_2436636_7	1133850.SHJG_5515	8.707e-08	60.0	COG3832@1|root,COG3832@2|Bacteria,2IIF0@201174|Actinobacteria	201174|Actinobacteria	J	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158518_k127_2436636_0	1403819.BATR01000022_gene806	5.354e-134	466.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158518_k127_2436636_4	926569.ANT_10990	4.705e-23	104.0	COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi	200795|Chloroflexi	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158518_k127_2436636_6	880073.Calab_0980	4.963e-09	68.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158518_k127_2436636_5	446466.Cfla_2127	4.61e-16	84.0	COG2072@1|root,COG2072@2|Bacteria,2GNGX@201174|Actinobacteria	201174|Actinobacteria	P	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
SRR25158518_k127_2444821_4	357808.RoseRS_2752	1.253e-75	260.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi,376K4@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158518_k127_2444821_2	742159.HMPREF0004_1186	3.027e-88	319.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria,3T24G@506|Alcaligenaceae	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158518_k127_2444821_0	1449080.JQMV01000003_gene1597	1.609e-149	500.0	COG1874@1|root,COG1874@2|Bacteria,1WJAT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SRR25158518_k127_2444821_8	926569.ANT_28890	5.345e-54	202.0	COG0697@1|root,COG0697@2|Bacteria,2G6ZR@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_2444821_6	479434.Sthe_3365	2.079e-65	231.0	COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi,27YZ8@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_2444821_7	479434.Sthe_3364	4.056e-57	221.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,27Z1H@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_2444821_9	479433.Caci_5561	3.593e-43	178.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158518_k127_2444821_3	204669.Acid345_1701	1.353e-87	303.0	COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria,2JI7E@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158518_k127_2444821_1	1463917.JODC01000009_gene8631	2.229e-116	390.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria	201174|Actinobacteria	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
SRR25158518_k127_2444821_5	1123320.KB889629_gene7830	2.875e-74	271.0	COG1349@1|root,COG1349@2|Bacteria,2GP4S@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators of sugar metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
SRR25158518_k127_2444821_10	1150474.JQJI01000008_gene1328	2.945e-38	161.0	COG1085@1|root,COG1085@2|Bacteria,2GBX8@200918|Thermotogae	200918|Thermotogae	H	PFAM galactose-1-phosphate uridyl transferase domain protein	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SRR25158518_k127_246074_6	1382356.JQMP01000003_gene1417	3.243e-74	259.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi,27Y7R@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_246074_1	405948.SACE_4181	4.958e-167	559.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4E23I@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158518_k127_246074_2	316274.Haur_2141	4.188e-123	413.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158518_k127_246074_3	1146883.BLASA_4010	1.185e-107	389.0	COG4262@1|root,COG4262@2|Bacteria,2I372@201174|Actinobacteria,4EUU4@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158518_k127_246074_9	1540221.JQNI01000002_gene751	9.528e-42	160.0	COG4329@1|root,COG4329@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2243
SRR25158518_k127_246074_8	106370.Francci3_0100	3.35e-43	168.0	COG1928@1|root,COG1928@2|Bacteria,2GQQV@201174|Actinobacteria	201174|Actinobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_246074_5	298654.FraEuI1c_6514	1.181e-78	275.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yunF	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158518_k127_246074_7	682795.AciX8_0326	1.242e-73	262.0	COG0438@1|root,COG0438@2|Bacteria,3Y6NY@57723|Acidobacteria,2JMG8@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158518_k127_246074_0	926550.CLDAP_17420	5.098e-196	651.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158518_k127_246074_10	1137269.AZWL01000010_gene5046	4.698e-36	143.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_246074_11	1122611.KB903952_gene6034	1.013e-32	145.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4EFJ2@85012|Streptosporangiales	201174|Actinobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158518_k127_246074_4	246194.CHY_0174	9.665e-97	334.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,24AAC@186801|Clostridia,42ENU@68295|Thermoanaerobacterales	186801|Clostridia	BQ	PFAM histone deacetylase superfamily	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158518_k127_247790_10	926550.CLDAP_38540	3.428e-05	49.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158518_k127_247790_0	1123253.AUBD01000002_gene1143	3.564e-153	500.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1X44Q@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158518_k127_247790_3	926550.CLDAP_03710	1.195e-62	226.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158518_k127_247790_7	742738.HMPREF9460_01062	1.276e-16	92.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,268FN@186813|unclassified Clostridiales	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158518_k127_247790_1	264732.Moth_0259	1.007e-90	315.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,42EVZ@68295|Thermoanaerobacterales	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158518_k127_247790_2	1009370.ALO_07683	6.68e-75	263.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H1X8@909932|Negativicutes	909932|Negativicutes	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158518_k127_247790_5	1382306.JNIM01000001_gene3747	1.037e-40	161.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158518_k127_247790_8	335541.Swol_1443	1.942e-09	69.0	COG1826@1|root,COG1826@2|Bacteria,1U4IP@1239|Firmicutes,259BB@186801|Clostridia,42K90@68298|Syntrophomonadaceae	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158518_k127_247790_4	309801.trd_0010	8.932e-51	205.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi,27XX0@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158518_k127_247790_6	383372.Rcas_2260	5.177e-17	94.0	COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,376BX@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158518_k127_247790_9	1236976.JCM16418_740	3.167e-05	49.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26QNN@186822|Paenibacillaceae	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
SRR25158518_k127_2482910_1	1120985.AUMI01000015_gene1473	1.547e-36	144.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4H4D6@909932|Negativicutes	909932|Negativicutes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158518_k127_2482910_0	717605.Theco_2184	3.785e-62	232.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,26RTF@186822|Paenibacillaceae	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
SRR25158518_k127_248706_10	1033739.CAEU01000054_gene387	6.946e-18	84.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,26D6R@186818|Planococcaceae	91061|Bacilli	P	Phosphate transporter family	pit	GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158518_k127_248706_5	671143.DAMO_1095	5.843e-42	163.0	COG1392@1|root,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	MA20_27875	-	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158518_k127_248706_9	479435.Kfla_1126	1.875e-28	130.0	2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_248706_1	240292.Ava_1652	1.667e-81	289.0	COG4122@1|root,COG4122@2|Bacteria,1G2Y6@1117|Cyanobacteria,1HK98@1161|Nostocales	1117|Cyanobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
SRR25158518_k127_248706_2	552811.Dehly_1189	7.094e-74	258.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,34D9D@301297|Dehalococcoidia	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_248706_6	40571.JOEA01000014_gene1776	1.309e-40	154.0	COG0454@1|root,COG0454@2|Bacteria,2IM52@201174|Actinobacteria,4E7W0@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_248706_0	429009.Adeg_0526	9.819e-131	435.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158518_k127_248706_8	1122939.ATUD01000001_gene395	2.696e-33	130.0	COG1476@1|root,COG1476@2|Bacteria,2IRJP@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158518_k127_248706_13	1032480.MLP_52800	4.683e-05	51.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158518_k127_248706_7	521098.Aaci_2086	1.306e-34	141.0	COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HG88@91061|Bacilli	91061|Bacilli	K	domain protein	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158518_k127_248706_11	478741.JAFS01000001_gene1271	1.485e-09	71.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,37G0Q@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	DnaJ molecular chaperone homology domain	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158518_k127_248706_3	373903.Hore_01750	4.656e-53	201.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,24CUE@186801|Clostridia,3WBDN@53433|Halanaerobiales	186801|Clostridia	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158518_k127_248706_4	926569.ANT_19840	1.548e-50	186.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158518_k127_250165_0	1120936.KB907221_gene2176	3.15e-16	88.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria	201174|Actinobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158518_k127_250165_1	1297742.A176_00544	3.191e-05	53.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,4320V@68525|delta/epsilon subdivisions,2WW8U@28221|Deltaproteobacteria,2YW2I@29|Myxococcales	28221|Deltaproteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C
SRR25158518_k127_2510411_1	383372.Rcas_0866	1.381e-73	261.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi,376SB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158518_k127_2510411_4	1380370.JIBA01000014_gene1693	1.262e-20	104.0	COG0681@1|root,COG0681@2|Bacteria,2IQMY@201174|Actinobacteria,4FHKK@85021|Intrasporangiaceae	201174|Actinobacteria	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158518_k127_2510411_0	484770.UFO1_1183	7.916e-177	592.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158518_k127_2510411_3	765420.OSCT_2140	3.559e-25	120.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8X1@200795|Chloroflexi,376YI@32061|Chloroflexia	32061|Chloroflexia	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
SRR25158518_k127_2510411_2	768704.Desmer_2846	3.165e-26	116.0	arCOG05253@1|root,30YM0@2|Bacteria,1U8SS@1239|Firmicutes,25HXR@186801|Clostridia,265WF@186807|Peptococcaceae	186801|Clostridia	S	YmaF family	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
SRR25158518_k127_2510613_1	717785.HYPMC_3549	5.31e-18	85.0	COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria,2TUUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LPPG Fo 2-phospho-L-lactate transferase	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158518_k127_2510613_0	1120950.KB892763_gene5533	5.363e-54	201.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DQPN@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2510613_2	1306174.JODP01000010_gene6968	1.88e-11	70.0	COG3467@1|root,COG3467@2|Bacteria,2IIWQ@201174|Actinobacteria	201174|Actinobacteria	S	F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158518_k127_2511459_8	365528.KB891233_gene1762	1.534e-19	94.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4EUWY@85013|Frankiales	201174|Actinobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158518_k127_2511459_4	494419.ALPM01000123_gene1421	2.345e-79	284.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria,1W8HX@1268|Micrococcaceae	201174|Actinobacteria	S	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158518_k127_2511459_10	1286631.X805_39930	7.939e-12	78.0	COG1011@1|root,COG1011@2|Bacteria,1N0I6@1224|Proteobacteria,2VR50@28216|Betaproteobacteria,1KKTK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	3.1.3.102,3.1.3.104	ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158518_k127_2511459_3	383372.Rcas_1080	4.975e-88	302.0	COG2189@1|root,COG2189@2|Bacteria,2G5WR@200795|Chloroflexi,376Z9@32061|Chloroflexia	32061|Chloroflexia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158518_k127_2511459_0	671143.DAMO_2896	3.219e-270	875.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158518_k127_2511459_7	316274.Haur_2692	5.305e-20	100.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158518_k127_2511459_1	518766.Rmar_0323	4.78e-132	439.0	COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1FIYS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158518_k127_2511459_2	1211115.ALIQ01000245_gene3667	2.624e-119	417.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,3NA3F@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Alpha-amylase domain	MA20_23410	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
SRR25158518_k127_2511459_6	1169152.AXVD01000009_gene158	1.439e-20	109.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4FUN6@85025|Nocardiaceae	201174|Actinobacteria	V	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158518_k127_2511459_5	479434.Sthe_1218	8.446e-39	162.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia	189775|Thermomicrobia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158518_k127_2511459_11	1075090.GOAMR_76_00560	6.711e-05	46.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria,4GGRX@85026|Gordoniaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158518_k127_2524642_0	329726.AM1_2520	8.953e-19	96.0	COG0705@1|root,COG0705@2|Bacteria,1FZY1@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158518_k127_2531487_0	926569.ANT_25740	1.884e-23	117.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
SRR25158518_k127_2531487_1	1205753.A989_05108	7.465e-06	55.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1X39Z@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_2547082_2	1146883.BLASA_1733	2.057e-116	387.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4ERKK@85013|Frankiales	201174|Actinobacteria	S	PFAM oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158518_k127_2547082_4	100226.SCO1665	6.75e-55	201.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158518_k127_2547082_3	469371.Tbis_1934	4.339e-79	276.0	COG5032@1|root,COG5032@2|Bacteria,2GME7@201174|Actinobacteria,4E044@85010|Pseudonocardiales	201174|Actinobacteria	BDLTU	PFAM Phosphatidylinositol 3- and 4-kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2547082_1	709986.Deima_3129	6.385e-153	514.0	COG0277@1|root,COG0277@2|Bacteria,1WI90@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	FAD linked oxidases, C-terminal domain	-	-	1.1.2.4,2.5.1.26	ko:K00102,ko:K00803	ko00565,ko00620,ko01100,ko04146,map00565,map00620,map01100,map04146	-	R00197,R04311	RC00020,RC00044,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158518_k127_2547082_0	926569.ANT_09270	3.022e-214	681.0	COG1070@1|root,COG1070@2|Bacteria,2G7TQ@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
SRR25158518_k127_2547082_5	1122622.ATWJ01000001_gene2572	1.187e-38	150.0	COG3187@1|root,COG3187@2|Bacteria,2I9ND@201174|Actinobacteria	201174|Actinobacteria	O	META domain	hslJ	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
SRR25158518_k127_2547383_0	1128421.JAGA01000003_gene2724	1.334e-37	146.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158518_k127_2547383_1	188626.HMPREF0321_1715	0.0003237	50.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,1ZVYJ@145357|Dermacoccaceae	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158518_k127_2547973_0	1192034.CAP_5178	7.008e-178	576.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158518_k127_2547973_4	765420.OSCT_0224	1.498e-35	155.0	COG0642@1|root,COG2205@2|Bacteria,2G8TQ@200795|Chloroflexi,377EU@32061|Chloroflexia	32061|Chloroflexia	T	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
SRR25158518_k127_2547973_5	118166.JH976537_gene827	6.533e-14	86.0	COG1196@1|root,COG1196@2|Bacteria,1G2AM@1117|Cyanobacteria,1HI0V@1150|Oscillatoriales	1117|Cyanobacteria	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158518_k127_2547973_1	404589.Anae109_4038	7.65e-175	554.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,438FV@68525|delta/epsilon subdivisions,2X3QT@28221|Deltaproteobacteria,2YWVJ@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158518_k127_2547973_3	42256.RradSPS_0124	4.35e-57	223.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158518_k127_2547973_6	287986.DV20_17035	2.439e-13	77.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E3X3@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158518_k127_2547973_7	59538.XP_005973742.1	3.216e-06	60.0	COG1506@1|root,KOG2100@2759|Eukaryota,39CYF@33154|Opisthokonta,3CNPF@33208|Metazoa,3E4V9@33213|Bilateria	33154|Opisthokonta	O	WD40-like Beta Propeller Repeat	dpp5	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158518_k127_2547973_2	390989.JOEG01000013_gene2562	1.965e-75	262.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158518_k127_2550652_5	1283299.AUKG01000001_gene1996	1.711e-10	62.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4CPP8@84995|Rubrobacteria	84995|Rubrobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158518_k127_2550652_6	1961.JOAK01000012_gene6236	4.345e-08	61.0	2EFF7@1|root,33981@2|Bacteria,2IFB2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2550652_1	469383.Cwoe_3190	3.19e-125	409.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CR9X@84995|Rubrobacteria	84995|Rubrobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158518_k127_2550652_0	867845.KI911784_gene3021	1.937e-132	437.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158518_k127_2550652_3	1223523.H340_19273	2.387e-37	155.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,2GMB5@201174|Actinobacteria	201174|Actinobacteria	T	PFAM Metallophosphoesterase	prpA	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
SRR25158518_k127_2550652_7	1173025.GEI7407_0591	7.1e-06	58.0	COG2350@1|root,COG2350@2|Bacteria,1G7RR@1117|Cyanobacteria,1HC4Z@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SRR25158518_k127_2550652_2	404589.Anae109_2816	5.381e-54	201.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_2550652_4	401526.TcarDRAFT_1987	2.877e-16	91.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4H37A@909932|Negativicutes	909932|Negativicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
SRR25158518_k127_2557751_0	1283287.KB822580_gene1798	1.727e-31	136.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DP9N@85009|Propionibacteriales	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158518_k127_2557751_2	335543.Sfum_4103	7.089e-07	60.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5H@1224|Proteobacteria,42SFF@68525|delta/epsilon subdivisions,2WP85@28221|Deltaproteobacteria,2MS8G@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158518_k127_2557751_1	42256.RradSPS_1525	2.621e-15	88.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158518_k127_2563370_1	1304875.JAFZ01000001_gene1406	6.36e-67	252.0	COG1200@1|root,COG1200@2|Bacteria,3TA8X@508458|Synergistetes	508458|Synergistetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158518_k127_2563370_0	1128421.JAGA01000002_gene200	2.522e-112	385.0	COG1461@1|root,COG1461@2|Bacteria,2NPHY@2323|unclassified Bacteria	2|Bacteria	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
SRR25158518_k127_2563370_2	445972.ANACOL_02744	0.0003245	49.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24NQK@186801|Clostridia,3WKX6@541000|Ruminococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
SRR25158518_k127_2569950_0	1192034.CAP_4250	6.126e-82	284.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales	28221|Deltaproteobacteria	G	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SRR25158518_k127_2569950_7	1384054.N790_08730	5.645e-28	118.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1X701@135614|Xanthomonadales	135614|Xanthomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158518_k127_2569950_1	1121468.AUBR01000007_gene240	4.161e-80	274.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,42FNG@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
SRR25158518_k127_2569950_6	292459.STH379	2.298e-45	178.0	COG1984@1|root,COG2049@1|root,COG1984@2|Bacteria,COG2049@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia	186801|Clostridia	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
SRR25158518_k127_2569950_5	1122963.AUHB01000012_gene1146	2.82e-52	204.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2TS7P@28211|Alphaproteobacteria,36XA6@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Allophanate hydrolase subunit 2	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	CT_A_B
SRR25158518_k127_2569950_2	1128421.JAGA01000002_gene1247	1.877e-78	295.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158518_k127_2569950_3	525904.Tter_1857	8.828e-71	250.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2569950_8	497965.Cyan7822_0545	3.865e-26	117.0	COG4106@1|root,COG4106@2|Bacteria,1GQ61@1117|Cyanobacteria,3KKTU@43988|Cyanothece	1117|Cyanobacteria	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158518_k127_2569950_4	292459.STH2211	2.943e-62	231.0	COG1470@1|root,COG1470@2|Bacteria,1TZ9A@1239|Firmicutes,24C4A@186801|Clostridia	186801|Clostridia	S	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
SRR25158518_k127_2577661_1	649638.Trad_2634	4.387e-95	320.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
SRR25158518_k127_2577661_4	1094980.Mpsy_2468	2.049e-08	64.0	arCOG05230@1|root,arCOG05230@2157|Archaea,2Y36Z@28890|Euryarchaeota,2NAJ8@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2577661_3	37919.EP51_25605	1.299e-24	121.0	COG1309@1|root,COG1309@2|Bacteria,2GQRD@201174|Actinobacteria,4FXP0@85025|Nocardiaceae	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158518_k127_2577661_0	1123320.KB889730_gene6070	3.019e-146	482.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158518_k127_2577661_2	390989.JOEG01000006_gene854	2.117e-61	220.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4DA0K@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158518_k127_2582437_3	1110502.TMO_1680	3.208e-21	100.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,2JR2C@204441|Rhodospirillales	204441|Rhodospirillales	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158518_k127_2582437_0	1206744.BAGL01000015_gene5854	1.268e-45	180.0	COG2017@1|root,COG2017@2|Bacteria,2HHH7@201174|Actinobacteria,4FYQA@85025|Nocardiaceae	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
SRR25158518_k127_2582437_2	13035.Dacsa_2593	7.172e-23	115.0	COG3210@1|root,COG3210@2|Bacteria,1GPZ7@1117|Cyanobacteria	2|Bacteria	U	Parallel beta-helix repeats	mshQ	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Laminin_G_3
SRR25158518_k127_2582437_1	525904.Tter_2060	4.873e-25	123.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR25158518_k127_2582437_4	309801.trd_1301	8.581e-06	51.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi,27YJ2@189775|Thermomicrobia	189775|Thermomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158518_k127_2591195_1	485913.Krac_6715	1.463e-99	343.0	COG1449@1|root,COG1449@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
SRR25158518_k127_2591195_0	926569.ANT_17340	7.641e-102	350.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SRR25158518_k127_2591195_2	1380390.JIAT01000009_gene1881	1.523e-09	70.0	COG3835@1|root,COG3835@2|Bacteria	2|Bacteria	KT	positive regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HTH_30
SRR25158518_k127_2640882_1	867845.KI911784_gene1387	4.126e-168	537.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,376WB@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158518_k127_2640882_4	68194.JNXR01000004_gene4442	3.662e-08	64.0	2DXF7@1|root,32V3D@2|Bacteria,2IKHE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2640882_2	1122176.KB903536_gene1836	1.14e-75	273.0	COG1680@1|root,COG1680@2|Bacteria,4NHA7@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158518_k127_2640882_3	1120934.KB894407_gene5092	7.908e-57	205.0	COG1695@1|root,COG1695@2|Bacteria,2I997@201174|Actinobacteria,4E5D8@85010|Pseudonocardiales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158518_k127_2640882_0	479434.Sthe_1003	5.422e-185	588.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158518_k127_2649113_0	1894.JOER01000017_gene4761	8.634e-36	140.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_2649113_1	266117.Rxyl_0847	1.462e-27	130.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CPJ5@84995|Rubrobacteria	84995|Rubrobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158518_k127_2658187_1	1123321.KB905813_gene808	2.526e-39	166.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158518_k127_2658187_0	1223544.GSI01S_47_00040	2.667e-48	183.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4GC4I@85026|Gordoniaceae	201174|Actinobacteria	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158518_k127_2658187_2	383372.Rcas_4453	1.06e-38	152.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi,375NU@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158518_k127_2665349_1	469382.Hbor_21080	2.938e-52	195.0	arCOG10176@1|root,arCOG10176@2157|Archaea,2XUE8@28890|Euryarchaeota,23S4Q@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
SRR25158518_k127_2665349_0	219305.MCAG_01458	1.737e-76	282.0	COG2273@1|root,COG2273@2|Bacteria,2GTJC@201174|Actinobacteria,4DJ0I@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SRR25158518_k127_2665349_2	670487.Ocepr_0734	3.265e-35	149.0	COG0560@1|root,COG0560@2|Bacteria,1WKQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
SRR25158518_k127_2665349_3	1158050.KB895452_gene661	2.015e-12	77.0	2AFVV@1|root,33H4H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2667647_0	1380370.JIBA01000013_gene1499	9.836e-270	844.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,4FESF@85021|Intrasporangiaceae	201174|Actinobacteria	HJM	Belongs to the MurCDEF family	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158518_k127_2682247_2	179408.Osc7112_3986	4.468e-69	252.0	COG2114@1|root,COG2202@1|root,COG2203@1|root,COG3447@1|root,COG2114@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3447@2|Bacteria,1FZXP@1117|Cyanobacteria,1H71W@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Guanylate_cyc,HAMP,MASE1,PAS_9,dCache_1
SRR25158518_k127_2682247_5	452637.Oter_1309	3.05e-13	77.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158518_k127_2682247_3	926550.CLDAP_34820	1.577e-31	143.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,HemolysinCabind,PPC,Peptidase_M8,Peptidase_S8,SLH
SRR25158518_k127_2682247_6	562970.Btus_1228	1.31e-09	65.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,2792X@186823|Alicyclobacillaceae	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158518_k127_2682247_0	469383.Cwoe_5782	1.864e-136	469.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I3CX@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158518_k127_2682247_1	404589.Anae109_2198	4.5e-80	279.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158518_k127_2682555_5	794903.OPIT5_15295	5.619e-18	94.0	COG0210@1|root,COG0210@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,AAA_32,DUF2075,Lon_C,NERD,PhoH,UvrD_C_2
SRR25158518_k127_2682555_3	1280948.HY36_11600	1.32e-21	107.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,43XS7@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158518_k127_2682555_6	1123242.JH636435_gene1123	4.29e-13	77.0	COG1595@1|root,COG1595@2|Bacteria,2IZJQ@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2682555_2	477641.MODMU_5190	9.62e-112	378.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4EUP4@85013|Frankiales	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158518_k127_2682555_4	324602.Caur_0298	2.491e-18	100.0	COG0823@1|root,COG3210@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2682555_7	1198114.AciX9_2275	6.492e-12	76.0	COG1917@1|root,COG1917@2|Bacteria,3Y596@57723|Acidobacteria,2JJRV@204432|Acidobacteriia	204432|Acidobacteriia	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158518_k127_2682555_1	1380391.JIAS01000019_gene1210	1.633e-144	465.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158518_k127_2682555_0	1297570.MESS4_720032	2.16e-169	541.0	COG1529@1|root,COG1529@2|Bacteria,1NNFR@1224|Proteobacteria,2TVHX@28211|Alphaproteobacteria,43R41@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	MA20_13965	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158518_k127_2683751_1	309801.trd_1386	5.208e-17	94.0	2DPD0@1|root,331J4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2683751_0	1382306.JNIM01000001_gene3725	1.213e-31	128.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi	200795|Chloroflexi	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158518_k127_2698846_1	290315.Clim_1144	7.043e-09	57.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
SRR25158518_k127_2698846_0	351160.RCIX51	2.189e-51	192.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT0T@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_2706120_0	525904.Tter_0430	1.25e-154	511.0	COG3250@1|root,COG3250@2|Bacteria,2NPI4@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SRR25158518_k127_2706120_2	1121378.KB899703_gene2317	5.439e-96	333.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SRR25158518_k127_2706120_1	926554.KI912637_gene3392	1.982e-122	400.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SRR25158518_k127_2709028_5	1713.JOFV01000001_gene1928	1.122e-07	54.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4F18R@85016|Cellulomonadaceae	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158518_k127_2709028_0	196162.Noca_3615	1.189e-86	297.0	COG0451@1|root,COG0451@2|Bacteria,2I1PI@201174|Actinobacteria,4DUKC@85009|Propionibacteriales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158518_k127_2709028_4	292459.STH961	3.548e-16	86.0	COG1309@1|root,COG1309@2|Bacteria,1V2VM@1239|Firmicutes,24RUF@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158518_k127_2709028_3	309801.trd_A0802	2.006e-28	123.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi,27YIQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
SRR25158518_k127_2709028_1	1128421.JAGA01000001_gene2348	3.261e-80	280.0	COG1478@1|root,COG1478@2|Bacteria,2NQRM@2323|unclassified Bacteria	2|Bacteria	S	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158518_k127_2709028_2	1394178.AWOO02000048_gene6370	5.114e-58	218.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4EIGV@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2710164_1	42256.RradSPS_0432	4.404e-64	236.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4CQ6X@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2710164_5	867903.ThesuDRAFT_01409	9.037e-22	108.0	COG2847@1|root,COG2847@2|Bacteria	2|Bacteria	P	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
SRR25158518_k127_2710164_4	309801.trd_0409	6.531e-29	133.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,27Z5W@189775|Thermomicrobia	189775|Thermomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158518_k127_2710164_0	1380370.JIBA01000015_gene171	7.273e-105	350.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FIR9@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_2710164_2	298655.KI912266_gene2031	1.047e-49	184.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4ESI6@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158518_k127_2710164_3	1278073.MYSTI_03456	5.045e-33	144.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SRR25158518_k127_2712730_2	1254432.SCE1572_20150	3.389e-23	106.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,4344K@68525|delta/epsilon subdivisions,2X57D@28221|Deltaproteobacteria,2Z07Z@29|Myxococcales	28221|Deltaproteobacteria	P	phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	1.14.15.7	ko:K00479,ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158518_k127_2712730_0	370438.PTH_1833	2.575e-105	366.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,260CQ@186807|Peptococcaceae	186801|Clostridia	J	exonuclease of the beta-lactamase fold involved in RNA	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
SRR25158518_k127_2712730_1	1449058.JQKT01000007_gene1235	5e-57	207.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,4FNSN@85023|Microbacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
SRR25158518_k127_2713166_2	1122182.KB903813_gene2815	2.537e-31	135.0	COG4529@1|root,COG4529@2|Bacteria,2GNX3@201174|Actinobacteria,4DAEP@85008|Micromonosporales	201174|Actinobacteria	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
SRR25158518_k127_2713166_1	696369.KI912183_gene2390	1.161e-46	187.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158518_k127_2713166_0	269799.Gmet_2673	9.919e-87	314.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,43U1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158518_k127_2721901_2	311424.DhcVS_1131	3.85e-11	65.0	COG0789@1|root,COG0789@2|Bacteria,2G9W3@200795|Chloroflexi,34DHG@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158518_k127_2721901_0	930169.B5T_03670	4.055e-112	379.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1XHDJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158518_k127_2721901_1	1382356.JQMP01000003_gene2113	3.818e-56	198.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl- CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158518_k127_2726593_0	861299.J421_1359	2e-13	83.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SRR25158518_k127_2729514_4	357808.RoseRS_3212	5.317e-12	68.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
SRR25158518_k127_2729514_2	1122622.ATWJ01000009_gene3108	6.254e-50	194.0	COG0726@1|root,COG2247@1|root,COG0726@2|Bacteria,COG2247@2|Bacteria,2HX9Q@201174|Actinobacteria,4FFZ3@85021|Intrasporangiaceae	201174|Actinobacteria	GM	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Polysacc_deac_1
SRR25158518_k127_2729514_1	67275.JOAP01000049_gene834	6.788e-62	225.0	COG0454@1|root,COG0456@2|Bacteria,2GK76@201174|Actinobacteria	201174|Actinobacteria	K	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_2729514_3	255470.cbdbA1315	1.581e-18	93.0	COG1714@1|root,COG1714@2|Bacteria,2GAT1@200795|Chloroflexi,34DA7@301297|Dehalococcoidia	301297|Dehalococcoidia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158518_k127_2729514_0	861299.J421_3175	5.092e-144	469.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158518_k127_2746743_5	1128421.JAGA01000003_gene2759	3.268e-64	242.0	COG1653@1|root,COG1653@2|Bacteria,2NQZ1@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158518_k127_2746743_1	1121378.KB899709_gene1054	3.157e-182	600.0	COG3507@1|root,COG3507@2|Bacteria,1WMKC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
SRR25158518_k127_2746743_9	1437608.BBIA_2383	9.419e-09	67.0	COG0454@1|root,COG0454@2|Bacteria,2I2G2@201174|Actinobacteria,4D0RY@85004|Bifidobacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
SRR25158518_k127_2746743_0	1382356.JQMP01000003_gene2339	3.489e-287	902.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158518_k127_2746743_10	1121324.CLIT_23c00460	4.107e-06	61.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia	186801|Clostridia	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158518_k127_2746743_8	1128421.JAGA01000002_gene1848	7.172e-25	121.0	COG4655@1|root,COG4655@2|Bacteria	2|Bacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
SRR25158518_k127_2746743_11	309801.trd_1013	1.015e-05	59.0	COG3745@1|root,COG3745@2|Bacteria,2G7H3@200795|Chloroflexi,27XF4@189775|Thermomicrobia	189775|Thermomicrobia	U	SAF	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
SRR25158518_k127_2746743_7	1382356.JQMP01000004_gene609	5.14e-36	156.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi,27Y6K@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158518_k127_2746743_3	326427.Cagg_1642	7.221e-112	397.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158518_k127_2746743_6	1128421.JAGA01000003_gene3265	1.271e-62	231.0	COG0266@1|root,COG0266@2|Bacteria,2NPGY@2323|unclassified Bacteria	2|Bacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158518_k127_2746743_4	570268.ANBB01000070_gene1567	1.228e-66	246.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4EGA1@85012|Streptosporangiales	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_2746743_2	292459.STH848	9.892e-162	541.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158518_k127_2757676_0	555088.DealDRAFT_0234	4.005e-190	612.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,42JRY@68298|Syntrophomonadaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158518_k127_2758289_1	1123075.AUDP01000010_gene1345	8.975e-66	237.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24IZV@186801|Clostridia,3WP8J@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
SRR25158518_k127_2758289_0	1385518.N798_12125	9.921e-68	232.0	2AKGE@1|root,30DHP@2|Bacteria,2I885@201174|Actinobacteria,4FH35@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2758289_2	1172188.KB911820_gene3085	7.327e-17	87.0	28RB9@1|root,2ZDQU@2|Bacteria,2GZQK@201174|Actinobacteria,4FIZG@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2758289_3	485913.Krac_11359	7.225e-06	49.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_2828743_0	479434.Sthe_0743	8.852e-91	325.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158518_k127_2828743_1	1157635.KB892004_gene4599	1.054e-22	109.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria	201174|Actinobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158518_k127_2828743_2	586413.CCDL010000003_gene3064	3.369e-12	68.0	COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,23IK3@182709|Oceanobacillus	91061|Bacilli	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_2834128_4	880073.Calab_0629	6.07e-97	330.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158518_k127_2834128_2	1128421.JAGA01000003_gene3002	4.755e-119	395.0	COG0074@1|root,COG0074@2|Bacteria,2NNZD@2323|unclassified Bacteria	2|Bacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158518_k127_2834128_6	926550.CLDAP_05380	2.709e-21	104.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
SRR25158518_k127_2834128_5	926569.ANT_02700	6.742e-34	136.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158518_k127_2834128_1	555079.Toce_1834	4.247e-214	680.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158518_k127_2834128_7	240015.ACP_2133	2.531e-15	84.0	COG4770@1|root,COG4770@2|Bacteria,3Y5TC@57723|Acidobacteria,2JNZR@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158518_k127_2834128_3	1269813.ATUL01000006_gene1760	1.36e-117	401.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1T1GN@1236|Gammaproteobacteria,1WVX4@135613|Chromatiales	135613|Chromatiales	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158518_k127_2834128_0	485913.Krac_12092	4.19e-239	754.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158518_k127_2834128_8	1437605.BACT_1486	2.544e-07	57.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CZ2D@85004|Bifidobacteriales	201174|Actinobacteria	D	CobQ CobB MinD ParA nucleotide binding domain protein	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158518_k127_2845726_0	1382356.JQMP01000003_gene2395	1.26e-79	279.0	COG5621@1|root,COG5621@2|Bacteria,2G6EI@200795|Chloroflexi,27YRR@189775|Thermomicrobia	189775|Thermomicrobia	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158518_k127_2845726_1	479434.Sthe_2035	1.255e-11	69.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158518_k127_2851515_0	1403819.BATR01000022_gene806	7.055e-133	448.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158518_k127_2851515_4	926569.ANT_10990	1.62e-22	106.0	COG0664@1|root,COG0664@2|Bacteria,2G92E@200795|Chloroflexi	200795|Chloroflexi	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158518_k127_2851515_5	880073.Calab_0980	1.53e-10	69.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158518_k127_2851515_2	446466.Cfla_2127	1.387e-46	187.0	COG2072@1|root,COG2072@2|Bacteria,2GNGX@201174|Actinobacteria	201174|Actinobacteria	P	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
SRR25158518_k127_2851515_6	1009370.ALO_05198	0.0007723	51.0	COG5061@1|root,COG5061@2|Bacteria,1VF12@1239|Firmicutes	1239|Firmicutes	OU	Protein of unknown function (DUF3307)	satE	-	-	-	-	-	-	-	-	-	-	-	DUF3307
SRR25158518_k127_2851515_1	1335757.SPICUR_04250	4.958e-120	413.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase S15	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158518_k127_2851515_3	504472.Slin_1662	2.28e-43	169.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158518_k127_2860164_2	1408473.JHXO01000001_gene2357	1.129e-11	73.0	COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,2FMXH@200643|Bacteroidia	976|Bacteroidetes	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
SRR25158518_k127_2860164_1	1287276.X752_10060	6.206e-100	334.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TRDT@28211|Alphaproteobacteria,43HF3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158518_k127_2860164_0	1298863.AUEP01000008_gene1247	1.32e-126	417.0	COG0404@1|root,COG0404@2|Bacteria,2I8C4@201174|Actinobacteria,4DTFF@85009|Propionibacteriales	201174|Actinobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1989,GCV_T,GCV_T_C
SRR25158518_k127_2871185_1	1121013.P873_04900	1.378e-21	102.0	COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2871185_0	1229172.JQFA01000002_gene2146	1.104e-76	273.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158518_k127_2871185_3	1121123.AUAO01000002_gene479	8.764e-11	71.0	COG1595@1|root,COG1595@2|Bacteria,1PBHM@1224|Proteobacteria,2UB0K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2871185_2	298654.FraEuI1c_4452	2.648e-18	96.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
SRR25158518_k127_2872204_0	1463857.JOFZ01000004_gene2674	7.502e-178	575.0	COG4992@1|root,COG4992@2|Bacteria,2GK0J@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158518_k127_2876580_1	653045.Strvi_1858	7.761e-16	78.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR25158518_k127_2876580_0	1382306.JNIM01000001_gene2829	8.038e-90	309.0	COG3367@1|root,COG3367@2|Bacteria	2|Bacteria	M	COGs COG3367 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N,Peptidase_S8
SRR25158518_k127_2876580_2	926690.KE386573_gene2587	0.0001912	50.0	COG4948@1|root,arCOG01168@2157|Archaea,2XUAK@28890|Euryarchaeota,23S9R@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158518_k127_2885759_1	1500894.JQNN01000001_gene723	9.48e-06	50.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
SRR25158518_k127_2885759_0	1035308.AQYY01000001_gene3255	7.197e-29	123.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META,YscW
SRR25158518_k127_2886562_0	1121468.AUBR01000058_gene877	4.846e-110	364.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,42F8P@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SRR25158518_k127_2886562_1	1235835.C814_03193	1.777e-90	313.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,3WGN9@541000|Ruminococcaceae	186801|Clostridia	C	thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158518_k127_2886562_2	1449126.JQKL01000002_gene1564	8.097e-47	174.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,26BJB@186813|unclassified Clostridiales	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SRR25158518_k127_2886562_3	1173027.Mic7113_4081	1.125e-18	91.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1HB2G@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
SRR25158518_k127_2886562_4	391625.PPSIR1_39885	0.0009972	48.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hoxW	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158518_k127_2892691_2	1266909.AUAG01000010_gene2665	2.013e-20	95.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Competence protein	gntX	GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158518_k127_2892691_1	574087.Acear_0275	1.044e-33	138.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3WAMR@53433|Halanaerobiales	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158518_k127_2892691_3	1380393.JHVP01000002_gene1562	4.963e-17	89.0	COG3860@1|root,COG3860@2|Bacteria,2IQEK@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20
SRR25158518_k127_2892691_0	485913.Krac_8850	1.005e-35	145.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158518_k127_2904355_2	479432.Sros_1653	6.924e-64	233.0	COG2197@1|root,COG2197@2|Bacteria,2GM61@201174|Actinobacteria,4EI7I@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158518_k127_2904355_1	1380390.JIAT01000010_gene4195	1.868e-85	304.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4CSC0@84995|Rubrobacteria	84995|Rubrobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158518_k127_2904355_3	1120949.KB903358_gene5088	5.878e-26	116.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GerE,HATPase_c_2,Response_reg
SRR25158518_k127_2904355_0	706587.Desti_0549	1.072e-181	586.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2MQ6H@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
SRR25158518_k127_2904454_3	450851.PHZ_c2115	1.253e-10	68.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSQN@28211|Alphaproteobacteria,2KEYU@204458|Caulobacterales	204458|Caulobacterales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_2904454_1	710696.Intca_0482	2.871e-50	194.0	COG0265@1|root,COG1286@1|root,COG0265@2|Bacteria,COG1286@2|Bacteria,2GJ92@201174|Actinobacteria,4FG7I@85021|Intrasporangiaceae	201174|Actinobacteria	O	Colicin V production protein	cvpA	-	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158518_k127_2904454_0	1128421.JAGA01000002_gene1557	1.639e-64	227.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
SRR25158518_k127_2904454_2	1340493.JNIF01000003_gene4562	1.446e-32	127.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SRR25158518_k127_2910849_2	317619.ANKN01000135_gene3382	1.14e-25	112.0	COG0764@1|root,COG0764@2|Bacteria,1G50G@1117|Cyanobacteria,1MM2G@1212|Prochloraceae	1117|Cyanobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcDH1_1363.fabZ,iJN678.fabZ	FabA
SRR25158518_k127_2910849_0	1382306.JNIM01000001_gene106	5.124e-142	477.0	COG0439@1|root,COG0439@2|Bacteria,2G5YA@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158518_k127_2910849_3	13690.CP98_00222	2.901e-10	68.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,2K5JX@204457|Sphingomonadales	204457|Sphingomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158518_k127_2910849_1	575540.Isop_1187	3.809e-31	128.0	COG0825@1|root,COG0825@2|Bacteria,2IX7N@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SRR25158518_k127_2911973_0	1472716.KBK24_0129010	4.83e-164	520.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VKE9@28216|Betaproteobacteria,1K07I@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158518_k127_2911973_1	1463853.JOHW01000015_gene109	1.326e-161	531.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria	201174|Actinobacteria	E	1-aminocyclopropane-1-carboxylate deaminase	acdS	-	3.5.99.7,4.4.1.15	ko:K01505,ko:K05396	ko00270,map00270	-	R00997,R01874	RC00382,RC00419	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158518_k127_2911973_8	405948.SACE_3482	5.147e-44	171.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria,4E1XR@85010|Pseudonocardiales	201174|Actinobacteria	Q	Chitin-binding domain type 3	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158518_k127_2911973_2	584708.Apau_0448	1.431e-125	423.0	COG0436@1|root,COG0436@2|Bacteria,3TARZ@508458|Synergistetes	508458|Synergistetes	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158518_k127_2911973_4	987059.RBXJA2T_07290	3.482e-89	308.0	COG2040@1|root,COG2040@2|Bacteria,1QTE6@1224|Proteobacteria,2VNST@28216|Betaproteobacteria,1KN00@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Homocysteine S-methyltransferase	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
SRR25158518_k127_2911973_6	926569.ANT_27040	2.191e-75	259.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	ycdQ	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
SRR25158518_k127_2911973_10	469371.Tbis_0130	9.301e-13	78.0	COG3226@1|root,COG3226@2|Bacteria,2I3XB@201174|Actinobacteria,4EEZ2@85010|Pseudonocardiales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158518_k127_2911973_7	983917.RGE_12730	3.671e-69	244.0	COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_8
SRR25158518_k127_2911973_3	479434.Sthe_1273	2.36e-119	407.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158518_k127_2911973_5	1382356.JQMP01000004_gene534	5.218e-79	284.0	COG0793@1|root,COG0793@2|Bacteria,2G6A8@200795|Chloroflexi,27Y0X@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
SRR25158518_k127_2915319_2	479434.Sthe_0254	3.383e-65	233.0	COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi,27XTA@189775|Thermomicrobia	189775|Thermomicrobia	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158518_k127_2915319_3	1894.JOER01000062_gene101	4.417e-52	194.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675,ko:K15466	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001,ko01000,ko01008	-	-	-	Acetyltransf_2
SRR25158518_k127_2915319_5	1120950.KB892739_gene3990	5.415e-24	115.0	COG0346@1|root,COG0346@2|Bacteria,2IPGW@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
SRR25158518_k127_2915319_0	105420.BBPO01000025_gene7106	1.266e-133	451.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,2NEFM@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2915319_4	543632.JOJL01000001_gene7751	2.242e-33	132.0	COG3795@1|root,COG3795@2|Bacteria,2IMHE@201174|Actinobacteria,4DGK5@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158518_k127_2915319_1	1120960.ATXG01000006_gene2345	2.338e-73	250.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4FKM8@85023|Microbacteriaceae	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158518_k127_2929847_4	1382306.JNIM01000001_gene592	1.975e-30	141.0	COG0248@1|root,COG0248@2|Bacteria,2G776@200795|Chloroflexi	200795|Chloroflexi	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	CHAD,HD,Ppx-GppA
SRR25158518_k127_2929847_2	383372.Rcas_3586	1.933e-40	175.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2G7FA@200795|Chloroflexi,375SS@32061|Chloroflexia	32061|Chloroflexia	FP	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH,HD
SRR25158518_k127_2929847_0	402777.KB235904_gene4017	9.815e-232	749.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1H9DA@1150|Oscillatoriales	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158518_k127_2929847_7	685778.AORL01000006_gene3441	1.995e-07	58.0	2EGVF@1|root,31AZQ@2|Bacteria,1Q6M5@1224|Proteobacteria,2V645@28211|Alphaproteobacteria,2KBZ3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2929847_3	646529.Desaci_2612	3.254e-35	155.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,26338@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SRR25158518_k127_2929847_5	485913.Krac_1345	2.164e-26	115.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
SRR25158518_k127_2929847_1	1382305.AZUC01000009_gene1906	4.722e-81	286.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,26DWU@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4162)	yhaQ	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_2929847_6	240015.ACP_1741	4.699e-18	100.0	COG1668@1|root,COG1668@2|Bacteria,3Y2XV@57723|Acidobacteria,2JIQK@204432|Acidobacteriia	204432|Acidobacteriia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_2938522_3	1121440.AUMA01000008_gene813	6.274e-52	186.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MBR8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158518_k127_2938522_4	936375.HMPREF1152_0550	3.408e-40	152.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WD8E@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158518_k127_2938522_0	671143.DAMO_0075	2.821e-96	324.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158518_k127_2938522_2	1401067.HMPREF0872_06655	4.801e-53	201.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H1Y8@909932|Negativicutes	909932|Negativicutes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158518_k127_2938522_5	926550.CLDAP_17130	3.102e-35	154.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158518_k127_2938522_1	264732.Moth_2246	1.426e-92	319.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,42EV8@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158518_k127_2948248_4	1121123.AUAO01000002_gene479	4.559e-22	107.0	COG1595@1|root,COG1595@2|Bacteria,1PBHM@1224|Proteobacteria,2UB0K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2948248_3	591157.SSLG_03223	4.301e-22	106.0	COG3404@1|root,COG3404@2|Bacteria,2IIRF@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
SRR25158518_k127_2948248_2	426114.THI_0794	4.942e-24	118.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2VRKE@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158518_k127_2948248_1	903818.KI912268_gene2220	9.747e-44	165.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
SRR25158518_k127_2948248_0	926550.CLDAP_24970	9.826e-125	412.0	COG3303@1|root,COG3303@2|Bacteria,2G5UX@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SRR25158518_k127_2958346_2	867903.ThesuDRAFT_00086	5.041e-60	233.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WCFS@538999|Clostridiales incertae sedis	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158518_k127_2958346_3	574087.Acear_1731	1.731e-47	184.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3WAKX@53433|Halanaerobiales	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
SRR25158518_k127_2958346_1	867903.ThesuDRAFT_00081	2.162e-67	239.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WCJM@538999|Clostridiales incertae sedis	186801|Clostridia	J	FtsJ-like methyltransferase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158518_k127_2958346_0	648996.Theam_0011	6.88e-92	316.0	COG1154@1|root,COG1154@2|Bacteria,2G3R7@200783|Aquificae	200783|Aquificae	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158518_k127_2963085_0	1121346.KB899811_gene1638	3.491e-90	318.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26QNN@186822|Paenibacillaceae	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
SRR25158518_k127_2963085_2	1382356.JQMP01000003_gene2165	6.919e-59	220.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,27Y1D@189775|Thermomicrobia	189775|Thermomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158518_k127_2963085_1	525904.Tter_0079	1.567e-84	302.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	6.3.2.2	ko:K01919,ko:K03072,ko:K12257	ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070	M00118,M00335	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	GshA,SecD_SecF,Sec_GG
SRR25158518_k127_2963085_4	1283299.AUKG01000001_gene2427	1.661e-27	131.0	COG5373@1|root,COG5373@2|Bacteria,2HRD8@201174|Actinobacteria,4CTAX@84995|Rubrobacteria	84995|Rubrobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158518_k127_2963085_3	525268.HMPREF0308_0665	7.191e-45	168.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,22JNI@1653|Corynebacteriaceae	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158518_k127_2974486_3	1121123.AUAO01000002_gene479	9.755e-19	93.0	COG1595@1|root,COG1595@2|Bacteria,1PBHM@1224|Proteobacteria,2UB0K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_2974486_2	1227739.Hsw_3983	6.878e-25	119.0	2E4YY@1|root,32ZSQ@2|Bacteria,4P5XB@976|Bacteroidetes,47W1A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2974486_0	1283299.AUKG01000001_gene3268	4.532e-178	567.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4CQX3@84995|Rubrobacteria	84995|Rubrobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
SRR25158518_k127_2974486_1	365528.KB891209_gene2164	3.526e-31	130.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4ESHX@85013|Frankiales	201174|Actinobacteria	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_2976141_2	926569.ANT_16170	1.291e-164	525.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158518_k127_2976141_0	485913.Krac_8971	3.435e-175	588.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158518_k127_2976141_4	1183438.GKIL_0560	1.05e-113	385.0	COG0025@1|root,COG0025@2|Bacteria,1G1WP@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM Na H antiporter, bacterial form	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158518_k127_2976141_3	526225.Gobs_1542	6.029e-130	428.0	COG3844@1|root,COG3844@2|Bacteria,2GMJQ@201174|Actinobacteria,4ERDH@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158518_k127_2976141_1	1131462.DCF50_p1447	2.034e-169	546.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,2608H@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158518_k127_2976141_5	1416759.AYMR01000018_gene2186	4.421e-99	347.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,MFS_3
SRR25158518_k127_2976141_8	1416759.AYMR01000018_gene2185	2.38e-49	183.0	COG0640@1|root,COG0640@2|Bacteria,2II9U@201174|Actinobacteria,4FQSN@85023|Microbacteriaceae	201174|Actinobacteria	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158518_k127_2976141_7	1380391.JIAS01000019_gene1295	3.083e-75	263.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,2JQ7X@204441|Rhodospirillales	204441|Rhodospirillales	E	COG1177 ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158518_k127_2976141_6	1245471.PCA10_08520	1.182e-87	299.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,1RNNZ@1236|Gammaproteobacteria,1YF36@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158518_k127_2976141_9	1304880.JAGB01000003_gene995	0.0001727	45.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia	186801|Clostridia	P	ABC transporter, solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
SRR25158518_k127_2976167_1	324602.Caur_3411	3.372e-24	108.0	COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158518_k127_2976167_0	1128421.JAGA01000003_gene3247	1.584e-84	301.0	COG2304@1|root,COG2304@2|Bacteria,2NQHG@2323|unclassified Bacteria	2|Bacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158518_k127_2976950_18	56107.Cylst_3965	4.466e-27	121.0	COG2271@1|root,COG2271@2|Bacteria,1GJ1Q@1117|Cyanobacteria,1HSWX@1161|Nostocales	1117|Cyanobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158518_k127_2976950_0	479435.Kfla_2107	1.639e-198	666.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2IAS1@201174|Actinobacteria,4DWMF@85009|Propionibacteriales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
SRR25158518_k127_2976950_20	221109.22778910	1.954e-17	98.0	COG0346@1|root,COG0346@2|Bacteria,1V5HJ@1239|Firmicutes,4HHR8@91061|Bacilli,23KYX@182709|Oceanobacillus	91061|Bacilli	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
SRR25158518_k127_2976950_3	190650.CC_3125	3.116e-112	381.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U0BD@28211|Alphaproteobacteria,2KK0G@204458|Caulobacterales	204458|Caulobacterales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158518_k127_2976950_12	106370.Francci3_2526	1.046e-42	173.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria,4ESU7@85013|Frankiales	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158518_k127_2976950_22	1121019.AUMN01000028_gene1790	4.655e-11	76.0	COG4095@1|root,COG4095@2|Bacteria,2H7V7@201174|Actinobacteria	201174|Actinobacteria	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
SRR25158518_k127_2976950_11	1110697.NCAST_11_01110	1.058e-47	177.0	COG5646@1|root,COG5646@2|Bacteria,2IINN@201174|Actinobacteria,4G0JA@85025|Nocardiaceae	201174|Actinobacteria	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158518_k127_2976950_8	316274.Haur_0572	2.329e-67	238.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2G975@200795|Chloroflexi	200795|Chloroflexi	K	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
SRR25158518_k127_2976950_9	1386089.N865_15870	2.262e-65	234.0	COG1708@1|root,COG1708@2|Bacteria,2I1CC@201174|Actinobacteria	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158518_k127_2976950_10	1501230.ET33_31970	3.274e-56	217.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
SRR25158518_k127_2976950_4	1289387.AUKW01000006_gene3905	9.95e-108	393.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158518_k127_2976950_16	469383.Cwoe_1809	4.202e-36	145.0	2CP0Z@1|root,32SI8@2|Bacteria,2IHXV@201174|Actinobacteria,4CQJ0@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
SRR25158518_k127_2976950_6	324602.Caur_0518	8.288e-95	317.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2976950_17	1380370.JIBA01000018_gene537	1.456e-34	137.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158518_k127_2976950_19	1500894.JQNN01000001_gene4480	1.228e-18	95.0	COG4244@1|root,COG4244@2|Bacteria	2|Bacteria	E	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158518_k127_2976950_24	1370120.AUWR01000106_gene1732	0.0006898	50.0	COG3427@1|root,COG3427@2|Bacteria,2IJF7@201174|Actinobacteria,238SI@1762|Mycobacteriaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158518_k127_2976950_13	195105.CN97_16705	2.619e-40	163.0	COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,2U0KA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Protein tyrosine serine phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
SRR25158518_k127_2976950_2	251221.35213035	1.069e-121	407.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
SRR25158518_k127_2976950_15	272943.RSP_1268	3.657e-36	158.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,1FBIP@1060|Rhodobacter	28211|Alphaproteobacteria	T	Osmosensitive K channel His kinase sensor	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR25158518_k127_2976950_23	118163.Ple7327_4530	9.146e-07	61.0	COG0784@1|root,COG2202@1|root,COG3852@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,3VHZD@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
SRR25158518_k127_2976950_14	500153.JOEK01000011_gene1877	4.281e-38	166.0	COG0699@1|root,COG0699@2|Bacteria,2GM68@201174|Actinobacteria	201174|Actinobacteria	K	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
SRR25158518_k127_2976950_7	1122994.AUFR01000037_gene1163	1.603e-89	326.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria,4DPB6@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158518_k127_2976950_5	1463825.JNXC01000023_gene4897	1.234e-96	326.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria,4DYI7@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158518_k127_2976950_1	653045.Strvi_1813	7.294e-185	598.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158518_k127_2976950_21	1122239.AULS01000001_gene1728	1e-13	74.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4FKGP@85023|Microbacteriaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158518_k127_2979255_0	1283287.KB822580_gene1798	4.117e-50	201.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DP9N@85009|Propionibacteriales	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158518_k127_2979255_1	335543.Sfum_4103	7.987e-12	75.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5H@1224|Proteobacteria,42SFF@68525|delta/epsilon subdivisions,2WP85@28221|Deltaproteobacteria,2MS8G@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
SRR25158518_k127_2979828_4	512565.AMIS_31020	3.927e-61	226.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158518_k127_2979828_6	1280692.AUJL01000001_gene167	3.412e-31	134.0	2C5N5@1|root,32Y15@2|Bacteria,1VEIC@1239|Firmicutes,24I2X@186801|Clostridia,36VBS@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2979828_3	1205680.CAKO01000006_gene3331	5.767e-79	278.0	COG5482@1|root,COG5482@2|Bacteria,1MWIN@1224|Proteobacteria,2TS4R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative PD-(D/E)XK phosphodiesterase (DUF2161)	MA20_28540	-	-	-	-	-	-	-	-	-	-	-	DUF2161
SRR25158518_k127_2979828_5	234267.Acid_3868	3.881e-52	197.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158518_k127_2979828_0	1121377.KB906428_gene1172	7.07e-136	456.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158518_k127_2979828_8	871968.DESME_03760	9.158e-08	59.0	COG0640@1|root,COG0640@2|Bacteria,1VCKP@1239|Firmicutes,24K7R@186801|Clostridia,265ZS@186807|Peptococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158518_k127_2979828_2	324602.Caur_0015	2.063e-117	392.0	COG0701@1|root,COG0701@2|Bacteria,2G6DW@200795|Chloroflexi,376WA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SRR25158518_k127_2979828_7	640081.Dsui_0925	2.752e-20	92.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VU78@28216|Betaproteobacteria,2KX1D@206389|Rhodocyclales	206389|Rhodocyclales	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
SRR25158518_k127_2979828_1	760568.Desku_1299	2.313e-122	438.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25ZY7@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158518_k127_2989773_8	351607.Acel_0571	6.805e-58	219.0	COG1028@1|root,COG1028@2|Bacteria,2GQBK@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158518_k127_2989773_2	1380390.JIAT01000010_gene4692	6.97e-140	458.0	COG1053@1|root,COG1053@2|Bacteria,2HD4N@201174|Actinobacteria	201174|Actinobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
SRR25158518_k127_2989773_6	1968.JOEV01000003_gene3298	9.835e-85	293.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
SRR25158518_k127_2989773_0	35754.JNYJ01000042_gene1381	1.488e-281	893.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria,4DID7@85008|Micromonosporales	201174|Actinobacteria	O	Acylphosphatase	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SRR25158518_k127_2989773_9	1449353.JQMQ01000004_gene6184	4.222e-26	112.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria,2NJ7C@228398|Streptacidiphilus	201174|Actinobacteria	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158518_k127_2989773_1	298653.Franean1_3401	2.436e-172	553.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria	201174|Actinobacteria	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SRR25158518_k127_2989773_3	1079986.JH164861_gene7309	1.639e-113	394.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria	201174|Actinobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SRR25158518_k127_2989773_4	591158.SSMG_03965	2.45e-104	352.0	COG0009@1|root,COG0009@2|Bacteria,2GN4J@201174|Actinobacteria	201174|Actinobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SRR25158518_k127_2989773_7	1128421.JAGA01000002_gene1190	5.672e-58	207.0	COG3059@1|root,COG3059@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
SRR25158518_k127_2989773_5	1123065.ATWL01000002_gene1464	1.203e-102	373.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria	201174|Actinobacteria	L	type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
SRR25158518_k127_2991609_3	314230.DSM3645_15875	8.944e-61	220.0	COG1092@1|root,COG1092@2|Bacteria,2J2ZW@203682|Planctomycetes	203682|Planctomycetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRR25158518_k127_2991609_2	314230.DSM3645_15870	1.135e-72	254.0	COG0566@1|root,COG0566@2|Bacteria,2IZJR@203682|Planctomycetes	203682|Planctomycetes	H	SpoU rRNA Methylase family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
SRR25158518_k127_2991609_1	266117.Rxyl_1765	3.089e-80	285.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CP8C@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158518_k127_2991609_0	1521187.JPIM01000060_gene2905	1.146e-82	298.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158518_k127_2991609_5	479434.Sthe_0413	2.003e-60	229.0	COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi,27XS0@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_2991609_15	326427.Cagg_1012	1.489e-14	82.0	COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi,37629@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
SRR25158518_k127_2991609_16	1304865.JAGF01000001_gene3136	2.057e-12	80.0	COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4F1WE@85016|Cellulomonadaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158518_k127_2991609_12	644283.Micau_3222	4.925e-21	104.0	COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4D8IR@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF881)	-	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF881
SRR25158518_k127_2991609_8	479434.Sthe_0719	7.221e-43	181.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,27XPY@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
SRR25158518_k127_2991609_6	243164.DET0573	1.53e-58	224.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
SRR25158518_k127_2991609_17	525904.Tter_2592	1.252e-10	73.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158518_k127_2991609_11	357808.RoseRS_3747	1.694e-27	122.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158518_k127_2991609_13	795797.C497_13091	3.932e-18	92.0	COG2259@1|root,arCOG02861@2157|Archaea,2XUDF@28890|Euryarchaeota,23U3B@183963|Halobacteria	183963|Halobacteria	S	DoxX family	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158518_k127_2991609_18	1101191.KI912577_gene4280	1.842e-05	57.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,1JQTV@119045|Methylobacteriaceae	28211|Alphaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
SRR25158518_k127_2991609_9	1394178.AWOO02000015_gene7095	6.718e-36	147.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria,4EKDT@85012|Streptosporangiales	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158518_k127_2991609_4	1121377.KB906432_gene905	1.347e-60	227.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
SRR25158518_k127_2991609_14	1160137.KB907308_gene7888	1.859e-15	89.0	COG1917@1|root,COG1917@2|Bacteria,2IRRU@201174|Actinobacteria,4G2WB@85025|Nocardiaceae	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_2991609_7	290317.Cpha266_0507	2.67e-43	165.0	COG2010@1|root,COG2010@2|Bacteria,1FEAI@1090|Chlorobi	1090|Chlorobi	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
SRR25158518_k127_2991609_10	398525.KB900701_gene5785	2.821e-33	139.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,3JW0V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
SRR25158518_k127_2995051_3	1089551.KE386572_gene269	6.958e-60	222.0	COG3467@1|root,COG3467@2|Bacteria,1MWQE@1224|Proteobacteria,2TR7J@28211|Alphaproteobacteria,4BSE6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	MA20_28490	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
SRR25158518_k127_2995051_4	635013.TherJR_2113	2.598e-48	198.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
SRR25158518_k127_2995051_0	1128421.JAGA01000003_gene2970	1.369e-132	436.0	COG0498@1|root,COG0498@2|Bacteria,2NP4T@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0546,iSB619.SA_RS06615,iYO844.BSU32250	PALP
SRR25158518_k127_2995051_2	1223542.GM1_039_00310	5.961e-72	261.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4GBVN@85026|Gordoniaceae	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158518_k127_2995051_1	255470.cbdbA1293	6.341e-97	329.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi,34CX6@301297|Dehalococcoidia	301297|Dehalococcoidia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158518_k127_300007_2	316274.Haur_0377	9.011e-48	173.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi,3754Q@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158518_k127_300007_1	743525.TSC_c11660	2.985e-53	216.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1WKSF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
SRR25158518_k127_300007_5	1266908.AQPB01000017_gene26	8.66e-17	87.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158518_k127_300007_6	118173.KB235914_gene2926	6.5e-10	72.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NACHT,NB-ARC,Pentapeptide,WD40
SRR25158518_k127_300007_0	1121272.KB903290_gene4616	5.213e-91	314.0	COG0025@1|root,COG0025@2|Bacteria,2I37Q@201174|Actinobacteria,4DM5R@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158518_k127_300007_4	195250.CM001776_gene467	2.61e-20	107.0	COG1653@1|root,COG1653@2|Bacteria,1G3MQ@1117|Cyanobacteria,1GZIG@1129|Synechococcus	1117|Cyanobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158518_k127_300007_3	1134445.AJJM01000219_gene2410	6.346e-28	132.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
SRR25158518_k127_3006184_1	994479.GL877882_gene6847	1.751e-124	425.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.21	ko:K07749,ko:K08298	-	-	R10643,R10644	RC00014,RC00131	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158518_k127_3006184_4	1463854.JOHT01000025_gene1152	0.0005814	51.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	eis	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158518_k127_3006184_3	643648.Slip_2315	2.1e-16	91.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,24AU8@186801|Clostridia,42KEU@68298|Syntrophomonadaceae	186801|Clostridia	V	Acetyltransferase (GNAT) domain	femX	-	2.3.2.10,2.3.2.16	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	-	R08776,R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
SRR25158518_k127_3006184_2	234621.RER_37010	1.903e-38	168.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4FUNH@85025|Nocardiaceae	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158518_k127_3006184_0	357808.RoseRS_0823	1.554e-288	916.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi,374YG@32061|Chloroflexia	32061|Chloroflexia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158518_k127_3035628_0	926560.KE387023_gene1701	4.324e-118	391.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158518_k127_3035628_1	945713.IALB_3093	1.561e-25	123.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,HisKA_2,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158518_k127_3044932_1	634177.GLX_25530	3.086e-64	235.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2JP8I@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158518_k127_3044932_0	1382306.JNIM01000001_gene404	5.66e-119	410.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SRR25158518_k127_3044932_2	1128421.JAGA01000002_gene514	3.145e-55	205.0	COG0169@1|root,COG0169@2|Bacteria,2NPR3@2323|unclassified Bacteria	2|Bacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158518_k127_3049555_5	313606.M23134_00969	4.898e-32	138.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158518_k127_3049555_3	525904.Tter_2554	2.918e-39	163.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158518_k127_3049555_8	931627.MycrhDRAFT_0222	7.474e-10	70.0	2DMMA@1|root,32SDH@2|Bacteria,2IM8C@201174|Actinobacteria,23AE5@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158518_k127_3049555_6	1173028.ANKO01000041_gene3226	8.536e-30	130.0	COG2085@1|root,COG2085@2|Bacteria,1G8DX@1117|Cyanobacteria,1HHG6@1150|Oscillatoriales	1117|Cyanobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SRR25158518_k127_3049555_0	1157638.KB892189_gene5632	3.882e-108	377.0	COG0249@1|root,COG0249@2|Bacteria,2IBYM@201174|Actinobacteria	201174|Actinobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
SRR25158518_k127_3049555_1	351607.Acel_0734	1.066e-96	337.0	COG0249@1|root,COG0249@2|Bacteria,2GNA7@201174|Actinobacteria	201174|Actinobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
SRR25158518_k127_3049555_4	485913.Krac_8826	4.824e-36	153.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158518_k127_3049555_2	472759.Nhal_0689	2.405e-80	277.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158518_k127_3049555_7	1128421.JAGA01000002_gene1806	1.132e-12	72.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158518_k127_305239_1	867903.ThesuDRAFT_01205	7.359e-45	184.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,24GE9@186801|Clostridia	186801|Clostridia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158518_k127_305239_0	221288.JH992901_gene4170	1.994e-80	292.0	COG0300@1|root,COG0300@2|Bacteria,1G3JI@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158518_k127_3063086_4	1370120.AUWR01000076_gene2674	6.696e-14	77.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,234RA@1762|Mycobacteriaceae	201174|Actinobacteria	C	F420-dependent oxidoreductase, Rv1855c family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3063086_1	1240349.ANGC01000052_gene4132	8.815e-95	323.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4FU05@85025|Nocardiaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158518_k127_3063086_2	411471.SUBVAR_05690	6.602e-83	288.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WGHP@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158518_k127_3063086_0	382464.ABSI01000009_gene3973	2.714e-115	395.0	COG0685@1|root,COG0685@2|Bacteria,46TD1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Methylene-tetrahydrofolate reductase C terminal	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
SRR25158518_k127_3063086_3	1122997.AUDD01000001_gene2466	1.752e-41	154.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4DPF3@85009|Propionibacteriales	201174|Actinobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158518_k127_3089751_9	1121272.KB903256_gene5661	4.235e-07	57.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,4DG1X@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3089751_2	1496688.ER33_12665	1.73e-114	400.0	COG0516@1|root,COG0516@2|Bacteria,1G1MX@1117|Cyanobacteria,22S1T@167375|Cyanobium	1117|Cyanobacteria	F	IMP dehydrogenase / GMP reductase domain	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158518_k127_3089751_1	1049564.TevJSym_ac01750	1.12e-122	425.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J5NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158518_k127_3089751_8	765952.PUV_25150	6.536e-11	71.0	COG0494@1|root,COG0494@2|Bacteria,2JG9I@204428|Chlamydiae	204428|Chlamydiae	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
SRR25158518_k127_3089751_0	1123320.KB889698_gene9323	5.475e-188	629.0	COG2133@1|root,COG3055@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,GSDH,Laminin_G_3,Malectin,PKD
SRR25158518_k127_3089751_4	309801.trd_0200	1.249e-32	134.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YHY@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
SRR25158518_k127_3089751_7	1206777.B195_11976	1.818e-14	86.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1SYS8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_9
SRR25158518_k127_3089751_3	35754.JNYJ01000038_gene4992	2.734e-53	199.0	COG0125@1|root,COG2211@1|root,COG0125@2|Bacteria,COG2211@2|Bacteria,2GNTI@201174|Actinobacteria,4DA19@85008|Micromonosporales	201174|Actinobacteria	FG	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_3,Thymidylate_kin
SRR25158518_k127_3089751_6	383372.Rcas_3145	6.241e-25	115.0	COG0680@1|root,COG0680@2|Bacteria,2G7BV@200795|Chloroflexi,3778G@32061|Chloroflexia	32061|Chloroflexia	C	PFAM peptidase M52 hydrogen uptake protein	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158518_k127_3089751_5	1382359.JIAL01000001_gene339	1.835e-29	126.0	COG1969@1|root,COG1969@2|Bacteria	2|Bacteria	C	respiratory electron transport chain	cybH	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158518_k127_3096858_1	745310.G432_15070	8.576e-23	106.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K04I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	2.3.1.174	ko:K07823	ko00362,ko01120,map00362,map01120	-	R00829	RC00004,RC00326	ko00000,ko00001,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158518_k127_3096858_2	1869.MB27_42030	1.757e-07	63.0	2DPD0@1|root,331J4@2|Bacteria,2IFZU@201174|Actinobacteria,4DCU1@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3096858_0	935565.JAEM01000035_gene2968	1.771e-67	240.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2PVD5@265|Paracoccus	28211|Alphaproteobacteria	I	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158518_k127_3105383_1	266117.Rxyl_1558	1.198e-98	345.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4CSWG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_3105383_0	247639.MGP2080_02481	6.656e-121	401.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,1RYN7@1236|Gammaproteobacteria,1JBXZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158518_k127_3105383_3	1043205.AFYF01000023_gene771	1.505e-11	67.0	COG2411@1|root,COG2411@2|Bacteria,2IN3A@201174|Actinobacteria,4FF1K@85021|Intrasporangiaceae	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3105383_2	394221.Mmar10_1066	7.408e-51	187.0	COG0494@1|root,COG0494@2|Bacteria,1Q4Q2@1224|Proteobacteria,2U785@28211|Alphaproteobacteria,440R1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158518_k127_31226_1	1077972.ARGLB_030_00040	1.368e-11	75.0	COG2508@1|root,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria	201174|Actinobacteria	QT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
SRR25158518_k127_31226_0	1382356.JQMP01000003_gene1524	4.175e-188	598.0	COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi,27XSZ@189775|Thermomicrobia	189775|Thermomicrobia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158518_k127_3132425_0	546414.Deide_15560	1.035e-71	256.0	COG1304@1|root,COG1304@2|Bacteria,1WJ7T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158518_k127_3134402_1	1370125.AUWT01000032_gene1634	1.881e-66	244.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
SRR25158518_k127_3134402_4	862751.SACTE_2228	9.487e-23	116.0	COG2203@1|root,COG2203@2|Bacteria,2I97I@201174|Actinobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
SRR25158518_k127_3134402_2	1278073.MYSTI_04304	2.084e-41	161.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158518_k127_3134402_3	479434.Sthe_0161	1.311e-38	166.0	COG2211@1|root,COG2211@2|Bacteria,2G6UD@200795|Chloroflexi,27XXJ@189775|Thermomicrobia	189775|Thermomicrobia	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158518_k127_3134402_0	106370.Francci3_0048	4.693e-165	567.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158518_k127_3145579_0	309801.trd_0391	6.292e-79	283.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
SRR25158518_k127_3145579_1	1382306.JNIM01000001_gene1871	1.229e-54	202.0	COG2897@1|root,COG2897@2|Bacteria,2G8GM@200795|Chloroflexi	200795|Chloroflexi	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158518_k127_3145579_4	1432050.IE4771_CH03553	1.039e-09	59.0	COG2141@1|root,COG2141@2|Bacteria,1MXQU@1224|Proteobacteria,2U1X1@28211|Alphaproteobacteria,4BC21@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3145579_3	1173022.Cri9333_4069	3.633e-24	110.0	COG2141@1|root,COG2141@2|Bacteria,1G3QW@1117|Cyanobacteria,1H9JG@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM Luciferase-like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3145579_2	222534.KB893728_gene5558	1.235e-36	145.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4ERMY@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3147557_2	1380356.JNIK01000018_gene800	2.807e-89	311.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4EREF@85013|Frankiales	201174|Actinobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158518_k127_3147557_3	266940.Krad_3620	1.968e-81	283.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_3147557_1	1120973.AQXL01000122_gene131	1.325e-102	344.0	COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,2794H@186823|Alicyclobacillaceae	91061|Bacilli	C	Zinc-binding dehydrogenase	yhfP	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158518_k127_3147557_7	1122611.KB903952_gene5823	6.427e-55	205.0	COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria,4EJGQ@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	blaB3	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158518_k127_3147557_6	1313172.YM304_33770	5.7e-56	213.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158518_k127_3147557_0	479431.Namu_1669	1.604e-103	349.0	COG0715@1|root,COG0715@2|Bacteria,2HU25@201174|Actinobacteria,4EWJ0@85013|Frankiales	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	ko:K15598	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	NMT1
SRR25158518_k127_3147557_4	1435356.Y013_21740	1.944e-73	261.0	COG0600@1|root,COG0600@2|Bacteria,2HMR9@201174|Actinobacteria,4FU97@85025|Nocardiaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15599	ko02010,map02010	M00442	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.3,3.A.1.17.6	-	-	BPD_transp_1
SRR25158518_k127_3147557_8	1536770.R50345_02580	4.228e-35	154.0	COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,26RPG@186822|Paenibacillaceae	91061|Bacilli	CP	Potassium ABC transporter permease	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_3147557_5	1273538.G159_12960	2.063e-59	214.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,26DWU@186818|Planococcaceae	91061|Bacilli	S	Domain of unknown function (DUF4162)	yhaQ	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_3156875_2	1463901.JOIY01000005_gene1846	1.076e-54	199.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158518_k127_3156875_3	1121946.AUAX01000046_gene7496	2.697e-36	140.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4DF48@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158518_k127_3156875_4	204669.Acid345_2214	2.252e-05	55.0	COG2217@1|root,COG2217@2|Bacteria,3Y39H@57723|Acidobacteria,2JHMU@204432|Acidobacteriia	204432|Acidobacteriia	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158518_k127_3156875_1	1166018.FAES_4781	2.574e-77	268.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,47JAY@768503|Cytophagia	976|Bacteroidetes	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SRR25158518_k127_3156875_0	614083.AWQR01000021_gene242	5.353e-139	448.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,4ABKH@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158518_k127_3185560_3	1121334.KB911078_gene1176	2.396e-16	85.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158518_k127_3185560_1	684949.ATTJ01000001_gene2186	6.086e-175	555.0	COG1883@1|root,COG1883@2|Bacteria	2|Bacteria	C	oxaloacetate decarboxylase activity	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
SRR25158518_k127_3185560_0	926550.CLDAP_15630	2.328e-183	609.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158518_k127_3185560_4	590998.Celf_2350	1.232e-10	73.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4F0P8@85016|Cellulomonadaceae	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158518_k127_3185560_2	292459.STH749	3.641e-64	238.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
SRR25158518_k127_3185560_5	1192034.CAP_1262	3.676e-05	55.0	COG3568@1|root,COG3568@2|Bacteria,1NJUY@1224|Proteobacteria,432E7@68525|delta/epsilon subdivisions,2WXI5@28221|Deltaproteobacteria,2YVNS@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158518_k127_3203454_2	1120950.KB892785_gene251	1.545e-83	305.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4DNA7@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158518_k127_3203454_0	391037.Sare_0771	3.361e-223	702.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4D9YX@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158518_k127_3203454_6	290397.Adeh_2673	2.647e-33	134.0	COG5478@1|root,COG5478@2|Bacteria,1MZMZ@1224|Proteobacteria,42VS8@68525|delta/epsilon subdivisions,2WWX7@28221|Deltaproteobacteria,2Z2GI@29|Myxococcales	28221|Deltaproteobacteria	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SRR25158518_k127_3203454_4	479434.Sthe_1007	9.068e-49	184.0	COG0500@1|root,COG2226@2|Bacteria,2G99K@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3203454_5	479434.Sthe_1006	5.979e-45	186.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	fixC	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRR25158518_k127_3203454_7	446466.Cfla_0514	7.667e-27	117.0	COG1051@1|root,COG1051@2|Bacteria,2IQZT@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158518_k127_3203454_8	479434.Sthe_1005	2.732e-18	96.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	ko:K05554,ko:K15885	ko01056,ko01130,map01056,map01130	M00778	R09265,R09268	RC02546,RC02547	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158518_k127_3203454_1	240016.ABIZ01000001_gene2166	7.889e-97	334.0	COG0304@1|root,COG0304@2|Bacteria,46U2G@74201|Verrucomicrobia,2IWM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158518_k127_3203454_3	561175.KB894095_gene2595	4.683e-72	245.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4EIC0@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158518_k127_3208093_1	56107.Cylst_3965	1.527e-27	117.0	COG2271@1|root,COG2271@2|Bacteria,1GJ1Q@1117|Cyanobacteria,1HSWX@1161|Nostocales	1117|Cyanobacteria	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158518_k127_3208093_3	1370121.AUWS01000070_gene362	1.228e-12	81.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria,23889@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158518_k127_3208093_2	292459.STH174	4.926e-25	110.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
SRR25158518_k127_3208093_0	263358.VAB18032_14305	1.763e-41	159.0	COG4572@1|root,COG4572@2|Bacteria,2IMHQ@201174|Actinobacteria,4DDJT@85008|Micromonosporales	201174|Actinobacteria	S	ChaB	-	-	-	-	-	-	-	-	-	-	-	-	ChaB,Rho_N
SRR25158518_k127_3208576_8	1150474.JQJI01000024_gene1595	0.0001352	52.0	COG0268@1|root,COG0268@2|Bacteria,2GDFA@200918|Thermotogae	200918|Thermotogae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158518_k127_3208576_2	263358.VAB18032_27071	5.351e-103	375.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158518_k127_3208576_0	926550.CLDAP_37960	1.779e-236	746.0	COG0166@1|root,COG0166@2|Bacteria,2G5ZM@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158518_k127_3208576_3	324602.Caur_1784	8.447e-100	339.0	COG3329@1|root,COG3329@2|Bacteria,2GAMM@200795|Chloroflexi,376S1@32061|Chloroflexia	32061|Chloroflexia	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
SRR25158518_k127_3208576_6	546414.Deide_17130	5.247e-33	143.0	COG0347@1|root,COG0347@2|Bacteria,1WK66@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3208576_7	1536774.H70357_34400	4.248e-20	103.0	2A6JV@1|root,30VDG@2|Bacteria,1VB09@1239|Firmicutes,4IRI3@91061|Bacilli,26QKN@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SRR25158518_k127_3208576_5	1122963.AUHB01000004_gene3057	2.57e-63	224.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2TRPD@28211|Alphaproteobacteria,36YCZ@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Carbonic anhydrase	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158518_k127_3208576_4	1121124.JNIX01000008_gene2577	8.869e-66	233.0	COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,2TV6N@28211|Alphaproteobacteria,2KFN9@204458|Caulobacterales	204458|Caulobacterales	S	L11 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PrmA
SRR25158518_k127_3208576_1	479434.Sthe_1219	1.283e-213	674.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi,27XM4@189775|Thermomicrobia	189775|Thermomicrobia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158518_k127_3215822_3	326427.Cagg_3618	4.604e-12	74.0	COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,3764Y@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158518_k127_3215822_0	1304865.JAGF01000001_gene77	7.788e-59	217.0	COG1595@1|root,COG1595@2|Bacteria,2GTCV@201174|Actinobacteria	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SRR25158518_k127_3215822_1	1095772.CAHH01000005_gene2326	2.869e-56	212.0	COG1876@1|root,COG1876@2|Bacteria,2IN2C@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M15B and M15C DD-carboxypeptidase VanY	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
SRR25158518_k127_3215822_2	42256.RradSPS_0432	9.012e-39	149.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4CQ6X@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3224273_0	1380394.JADL01000008_gene3474	6.312e-228	720.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158518_k127_3224273_1	449447.MAE_49220	1.828e-05	57.0	COG1595@1|root,COG1595@2|Bacteria,1G5PA@1117|Cyanobacteria	1117|Cyanobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158518_k127_3239349_1	926564.KI911756_gene6070	1.233e-56	207.0	COG1011@1|root,COG1011@2|Bacteria,2GPJ4@201174|Actinobacteria,4F35C@85017|Promicromonosporaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase,Hydrolase_like
SRR25158518_k127_3239349_2	1306174.JODP01000009_gene6556	9.047e-25	120.0	COG4963@1|root,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria	201174|Actinobacteria	D	Pilus assembly protein	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
SRR25158518_k127_3239349_0	1101188.KI912155_gene1728	1.336e-127	420.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,1W7G0@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158518_k127_3240550_1	671143.DAMO_2064	1.028e-52	190.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158518_k127_3240550_2	765420.OSCT_1025	6.956e-36	144.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,3772Y@32061|Chloroflexia	32061|Chloroflexia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158518_k127_3240550_0	309801.trd_0619	1.248e-63	228.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158518_k127_3240550_3	1358423.N180_02035	0.0005002	48.0	COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,1IRS0@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
SRR25158518_k127_3273438_1	626418.bglu_1g30340	4.155e-41	163.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1K3N3@119060|Burkholderiaceae	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158518_k127_3273438_0	298654.FraEuI1c_6811	1.193e-104	359.0	COG0208@1|root,COG0208@2|Bacteria,2GKGZ@201174|Actinobacteria,4ERZN@85013|Frankiales	201174|Actinobacteria	F	Fatty acid desaturase	-	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
SRR25158518_k127_3273438_2	1027371.GOALK_099_00900	1.378e-33	138.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4GBAX@85026|Gordoniaceae	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158518_k127_3296972_1	443255.SCLAV_0140	6.003e-70	250.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria	201174|Actinobacteria	F	nucleoside hydrolase	ybeK	-	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158518_k127_3296972_5	1463887.KL589954_gene7191	0.0003818	52.0	COG2318@1|root,COG2318@2|Bacteria,2GXK3@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158518_k127_3296972_0	911008.GLAD_03585	2.274e-98	334.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,1RSCY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the IUNH family	rihA	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0047405,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_0645,iECSE_1348.ECSE_0721,iEcE24377_1341.EcE24377A_0679,iSbBS512_1146.SbBS512_E0598	IU_nuc_hydro
SRR25158518_k127_3296972_3	1442599.JAAN01000041_gene3103	1.285e-30	130.0	COG2755@1|root,COG2755@2|Bacteria,1RE1B@1224|Proteobacteria,1S3DM@1236|Gammaproteobacteria,1X613@135614|Xanthomonadales	135614|Xanthomonadales	E	Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158518_k127_3296972_2	479434.Sthe_0621	1.608e-57	218.0	COG5401@1|root,COG5401@2|Bacteria,2GA61@200795|Chloroflexi,27Y9M@189775|Thermomicrobia	189775|Thermomicrobia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158518_k127_3296972_4	100226.SCO7534	5.684e-24	105.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158518_k127_330519_15	1121472.AQWN01000006_gene1665	1.299e-20	99.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158518_k127_330519_10	509190.Cseg_1212	5.953e-42	161.0	COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,2U59M@28211|Alphaproteobacteria,2KIPE@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
SRR25158518_k127_330519_12	1172180.KB911778_gene4695	5.416e-40	155.0	COG0346@1|root,COG0346@2|Bacteria,2IHX4@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158518_k127_330519_9	930171.Asphe3_21050	1.121e-48	186.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158518_k127_330519_18	298654.FraEuI1c_0068	3.042e-05	50.0	COG2905@1|root,COG2905@2|Bacteria,2GQMA@201174|Actinobacteria,4EX04@85013|Frankiales	201174|Actinobacteria	T	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
SRR25158518_k127_330519_11	1122611.KB903963_gene4728	2.084e-40	172.0	29QD5@1|root,30BCD@2|Bacteria,2IG1I@201174|Actinobacteria,4EGQ5@85012|Streptosporangiales	201174|Actinobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695
SRR25158518_k127_330519_19	561175.KB894098_gene5178	0.000308	49.0	COG0346@1|root,COG0346@2|Bacteria,2IHZH@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158518_k127_330519_1	397278.JOJN01000008_gene2467	6.089e-168	545.0	COG0154@1|root,COG0154@2|Bacteria,2GSDB@201174|Actinobacteria,4DPCU@85009|Propionibacteriales	201174|Actinobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158518_k127_330519_3	1380354.JIAN01000005_gene1924	1.329e-137	464.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,YkuD
SRR25158518_k127_330519_13	1001240.GY21_06265	2.842e-39	168.0	COG1520@1|root,COG1520@2|Bacteria,2IJK1@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
SRR25158518_k127_330519_7	1713.JOFV01000014_gene881	3.364e-94	316.0	COG1573@1|root,COG1573@2|Bacteria,2IE93@201174|Actinobacteria,4F2MC@85016|Cellulomonadaceae	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158518_k127_330519_6	477184.KYC_22286	3.156e-94	339.0	COG2267@1|root,COG4870@1|root,COG2267@2|Bacteria,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
SRR25158518_k127_330519_4	710696.Intca_0200	2.946e-130	433.0	COG0402@1|root,COG0402@2|Bacteria,2IB7M@201174|Actinobacteria,4FICR@85021|Intrasporangiaceae	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158518_k127_330519_2	596153.Alide_4107	1.415e-138	456.0	COG3170@1|root,COG3170@2|Bacteria,1R3TU@1224|Proteobacteria,2W0Y1@28216|Betaproteobacteria,4AGWU@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Belongs to the peptidase M12A family	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
SRR25158518_k127_330519_5	67356.KL575624_gene2081	5.09e-103	345.0	COG0189@1|root,COG0189@2|Bacteria,2I8TP@201174|Actinobacteria	201174|Actinobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
SRR25158518_k127_330519_16	47763.JNZA01000002_gene3336	7.269e-13	76.0	28VG6@1|root,2ZHIQ@2|Bacteria,2ITBN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	YscW
SRR25158518_k127_330519_14	998674.ATTE01000001_gene3077	2.913e-32	145.0	296JA@1|root,2ZTUV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_330519_0	1150399.AQYK01000001_gene597	4.763e-178	570.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4FNF7@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21,3.2.1.86	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
SRR25158518_k127_330519_8	1352941.M877_08730	7.611e-84	289.0	COG1073@1|root,COG1073@2|Bacteria,2I44C@201174|Actinobacteria	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158518_k127_3306320_2	1077972.ARGLB_080_00250	3.576e-47	181.0	COG1670@1|root,COG1670@2|Bacteria,2IHXG@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferases including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158518_k127_3306320_3	1385515.N791_12180	3.052e-15	79.0	COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,1SG29@1236|Gammaproteobacteria,1X727@135614|Xanthomonadales	135614|Xanthomonadales	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158518_k127_3306320_1	383372.Rcas_0305	5.238e-49	198.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,375CG@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158518_k127_3306320_0	1459636.NTE_02649	3.349e-107	351.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158518_k127_3308962_0	670307.HYPDE_26218	9.283e-201	653.0	COG3408@1|root,COG3408@2|Bacteria,1QQ0U@1224|Proteobacteria,2U25D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Trehalase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158518_k127_3308962_1	635013.TherJR_0702	2.671e-147	480.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,2603A@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM Ammonium transporter	nrgA	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158518_k127_3308962_5	525904.Tter_0667	1.49e-44	186.0	COG2259@1|root,COG2259@2|Bacteria,2NQ22@2323|unclassified Bacteria	2|Bacteria	S	DoxX	doxD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158518_k127_3308962_3	1306174.JODP01000010_gene7021	3.121e-60	223.0	COG2021@1|root,COG2021@2|Bacteria,2I5C3@201174|Actinobacteria	201174|Actinobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158518_k127_3308962_2	997346.HMPREF9374_1742	9.651e-62	221.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,27C40@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	KR domain	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158518_k127_3308962_9	1157640.AQWO01000001_gene6355	3.374e-05	57.0	COG4585@1|root,COG4585@2|Bacteria,2GMZS@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158518_k127_3308962_6	1245475.ANAE01000169_gene1817	4.557e-27	118.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EIZZ@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158518_k127_3308962_4	1380391.JIAS01000004_gene2970	1.223e-50	201.0	COG3386@1|root,COG3386@2|Bacteria,1RJY7@1224|Proteobacteria	1224|Proteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158518_k127_3308962_8	1048339.KB913029_gene3876	1.187e-05	56.0	2EN76@1|root,33FV1@2|Bacteria,2GYKJ@201174|Actinobacteria,4ETHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3308962_7	927677.ALVU02000001_gene2370	9.48e-19	88.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158518_k127_3317221_3	477641.MODMU_4784	1.936e-81	291.0	COG2319@1|root,COG3391@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3391@2|Bacteria,COG3629@2|Bacteria,2GJN3@201174|Actinobacteria,4ES8H@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,PD40,Trans_reg_C,WD40
SRR25158518_k127_3317221_6	1304878.AUGD01000012_gene4110	3.621e-16	87.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,2UIDR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3317221_2	926554.KI912653_gene4146	1.397e-95	334.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158518_k127_3317221_4	1713.JOFV01000004_gene3310	2.637e-37	154.0	COG1808@1|root,COG1808@2|Bacteria,2HXWI@201174|Actinobacteria,4F1B5@85016|Cellulomonadaceae	201174|Actinobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158518_k127_3317221_5	1463901.JOIY01000005_gene1762	1.246e-30	135.0	29VND@1|root,30H5P@2|Bacteria,2ICBQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3317221_0	1035308.AQYY01000001_gene3249	6.326e-262	821.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,260W7@186807|Peptococcaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
SRR25158518_k127_3317221_1	512565.AMIS_31020	3.57e-118	392.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
SRR25158518_k127_3317249_0	1379270.AUXF01000007_gene919	8.272e-47	178.0	COG5587@1|root,COG5587@2|Bacteria,1ZTH8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158518_k127_3317249_1	446470.Snas_5909	1.746e-19	99.0	2EB78@1|root,3357V@2|Bacteria,2H0NN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3321877_2	525909.Afer_1825	2.421e-145	491.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CN9T@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome b/b6/petB	-	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158518_k127_3321877_11	525909.Afer_1826	3.618e-59	229.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4CNF9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158518_k127_3321877_14	222534.KB893711_gene4996	3.078e-48	184.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,4ESET@85013|Frankiales	201174|Actinobacteria	C	cytochrome C	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158518_k127_3321877_12	926554.KI912633_gene3763	1.392e-52	197.0	COG0514@1|root,COG0514@2|Bacteria,1WJC6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
SRR25158518_k127_3321877_15	937777.Deipe_2143	7.88e-28	126.0	COG0514@1|root,COG0514@2|Bacteria,1WJC6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM ATP-dependent DNA helicase, RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
SRR25158518_k127_3321877_7	62928.azo1719	7.08e-89	320.0	COG0463@1|root,COG0463@2|Bacteria,1R3WX@1224|Proteobacteria,2VRNM@28216|Betaproteobacteria,2KWS8@206389|Rhodocyclales	206389|Rhodocyclales	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254,Glycos_transf_2
SRR25158518_k127_3321877_3	1183438.GKIL_0947	1.023e-114	396.0	COG0859@1|root,COG2870@1|root,COG0859@2|Bacteria,COG2870@2|Bacteria,1G4H4@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR25158518_k127_3321877_1	1540221.JQNI01000004_gene325	1.043e-157	523.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SRR25158518_k127_3321877_13	247490.KSU1_D0500	9.278e-50	200.0	COG0241@1|root,COG0241@2|Bacteria,2J080@203682|Planctomycetes	203682|Planctomycetes	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR25158518_k127_3321877_8	1095769.CAHF01000008_gene3617	1.877e-79	279.0	COG4221@1|root,COG4221@2|Bacteria,1QMNH@1224|Proteobacteria,2VKU7@28216|Betaproteobacteria,475EX@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158518_k127_3321877_0	1540221.JQNI01000004_gene328	5.182e-191	631.0	COG0279@1|root,COG0438@1|root,COG0279@2|Bacteria,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gmhA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008968,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016866,GO:0016868,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_4,Glycos_transf_1,SIS_2
SRR25158518_k127_3321877_5	1476583.DEIPH_ctg011orf0137	5.913e-102	357.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
SRR25158518_k127_3321877_6	479434.Sthe_0044	1.202e-90	315.0	COG0859@1|root,COG0859@2|Bacteria,2GA3H@200795|Chloroflexi,27Z0G@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR25158518_k127_3321877_9	1095769.CAHF01000008_gene3632	5.934e-79	281.0	COG0859@1|root,COG0859@2|Bacteria,1R57H@1224|Proteobacteria,2VHFC@28216|Betaproteobacteria,476YY@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR25158518_k127_3321877_4	861299.J421_2962	2.555e-106	365.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
SRR25158518_k127_3321877_16	1137269.AZWL01000006_gene6565	2.819e-13	74.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158518_k127_3321877_10	525904.Tter_2639	2.477e-61	220.0	COG5637@1|root,COG5637@2|Bacteria,2NRUC@2323|unclassified Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158518_k127_3337840_5	1229780.BN381_810009	3.262e-45	177.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3337840_6	309801.trd_1336	6.077e-39	166.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158518_k127_3337840_0	1382356.JQMP01000004_gene261	5.159e-317	994.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,27XYD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158518_k127_3337840_1	479434.Sthe_0519	1.255e-167	548.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158518_k127_3337840_3	685727.REQ_04900	2.63e-107	367.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4FVHF@85025|Nocardiaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
SRR25158518_k127_3337840_7	744979.R2A130_2801	5.96e-38	161.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Metal-dependent hydrolase	MA20_23375	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158518_k127_3337840_2	1463887.KL589986_gene2992	1.14e-107	366.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
SRR25158518_k127_3337840_4	744872.Spica_0828	3.74e-91	308.0	COG1175@1|root,COG1175@2|Bacteria,2J5SW@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10233	ko02010,map02010	M00201,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158518_k127_3344249_3	278957.ABEA03000151_gene4127	1.175e-55	201.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,3K7TR@414999|Opitutae	414999|Opitutae	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
SRR25158518_k127_3344249_2	1122939.ATUD01000004_gene3844	6.288e-98	337.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158518_k127_3344249_0	1122138.AQUZ01000030_gene4632	4.457e-154	499.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4DPK2@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158518_k127_3344249_1	1173264.KI913949_gene362	1.361e-147	479.0	COG1252@1|root,COG1252@2|Bacteria,1G20T@1117|Cyanobacteria,1H80B@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase, FAD-containing subunit	ndbA	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158518_k127_3344249_4	96561.Dole_2657	2.832e-35	136.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158518_k127_3347986_0	926560.KE387023_gene2049	8.032e-122	437.0	COG5001@1|root,COG5001@2|Bacteria,1WK20@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4
SRR25158518_k127_3347986_1	1121403.AUCV01000001_gene944	1.405e-45	174.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,2MJCA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
SRR25158518_k127_3347986_2	1123065.ATWL01000016_gene1988	3.024e-29	126.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria	201174|Actinobacteria	S	adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SRR25158518_k127_3352723_0	1313172.YM304_14090	2.797e-102	346.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	thiY	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158518_k127_3352723_1	1123389.ATXJ01000004_gene1278	2.481e-56	202.0	COG0473@1|root,COG0473@2|Bacteria,1WIRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158518_k127_3353267_1	58123.JOFJ01000004_gene1747	8.173e-41	151.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4EGX0@85012|Streptosporangiales	201174|Actinobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158518_k127_3353267_0	1120936.KB907211_gene535	3.941e-112	377.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4EG2B@85012|Streptosporangiales	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SRR25158518_k127_3353267_3	595460.RRSWK_02799	2.29e-15	87.0	COG0589@1|root,COG0589@2|Bacteria,2J48V@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158518_k127_3353267_2	65497.JODV01000008_gene132	1.513e-26	111.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4E0HP@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_3354258_1	1089544.KB912942_gene3327	1.167e-87	303.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DZQU@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_3354258_0	469383.Cwoe_3861	8.381e-126	413.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,4CRKG@84995|Rubrobacteria	2|Bacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_3364164_5	926550.CLDAP_19240	7.372e-14	71.0	COG0543@1|root,COG0543@2|Bacteria,2G7HU@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.3	ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158518_k127_3364164_2	747365.Thena_0401	2.624e-116	384.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia	186801|Clostridia	M	epimerase dehydratase	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158518_k127_3364164_4	211114.JOEF01000007_gene879	4.342e-17	87.0	COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria,4E4YD@85010|Pseudonocardiales	201174|Actinobacteria	T	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158518_k127_3364164_0	391625.PPSIR1_39870	3.033e-156	523.0	COG0479@1|root,COG0543@1|root,COG0479@2|Bacteria,COG0543@2|Bacteria,1QVWG@1224|Proteobacteria,43BWA@68525|delta/epsilon subdivisions,2X771@28221|Deltaproteobacteria,2YUJP@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
SRR25158518_k127_3364164_3	391625.PPSIR1_39875	5.121e-83	309.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42U69@68525|delta/epsilon subdivisions,2WQJZ@28221|Deltaproteobacteria,2YU5S@29|Myxococcales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
SRR25158518_k127_3364164_1	622637.KE124774_gene1614	2.051e-119	408.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2TYKR@28211|Alphaproteobacteria,36Z9G@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Nickel-dependent hydrogenase	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SRR25158518_k127_3368248_2	1313172.YM304_04030	2.171e-23	109.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
SRR25158518_k127_3368248_6	644966.Tmar_0321	2.984e-08	65.0	COG2010@1|root,COG2010@2|Bacteria,1VX6C@1239|Firmicutes,251IR@186801|Clostridia	186801|Clostridia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
SRR25158518_k127_3368248_7	309807.SRU_2694	1.607e-07	64.0	COG3055@1|root,COG3055@2|Bacteria,4PFB2@976|Bacteroidetes,1FKE3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3368248_3	926550.CLDAP_39730	2.871e-20	95.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	pspE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158518_k127_3368248_8	926560.KE387023_gene2074	2.082e-06	56.0	COG1547@1|root,COG1547@2|Bacteria,1WKCC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158518_k127_3368248_5	1348663.KCH_20650	5.745e-09	69.0	2BNAC@1|root,32GXY@2|Bacteria,2I1HN@201174|Actinobacteria,2M3WM@2063|Kitasatospora	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3368248_4	1111069.TCCBUS3UF1_20390	6.9e-14	79.0	COG4911@1|root,COG4911@2|Bacteria,1WJWB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158518_k127_3368248_0	1267535.KB906767_gene1544	5.539e-139	451.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria,2JMAM@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158518_k127_3368248_1	1125863.JAFN01000001_gene401	2.025e-125	415.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158518_k127_338662_4	1242864.D187_008994	3.679e-05	52.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158518_k127_338662_0	1445613.JALM01000076_gene184	5.282e-74	258.0	2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria,4E354@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_338662_1	1078083.HMPREF1208_01282	9.857e-40	164.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,4GX76@90964|Staphylococcaceae	91061|Bacilli	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158518_k127_338662_3	1280390.CBQR020000049_gene960	3.088e-38	150.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,4HJ56@91061|Bacilli,26SDF@186822|Paenibacillaceae	91061|Bacilli	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SRR25158518_k127_338662_2	644284.Arch_1470	2.372e-39	149.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4D53E@85005|Actinomycetales	201174|Actinobacteria	O	Cytochrome C assembly protein	resC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158518_k127_3387640_7	1304875.JAFZ01000001_gene1109	7.963e-18	83.0	COG1173@1|root,COG1173@2|Bacteria,3T9UM@508458|Synergistetes	508458|Synergistetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158518_k127_3387640_0	644966.Tmar_1797	3.567e-118	391.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WCYH@538999|Clostridiales incertae sedis	186801|Clostridia	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158518_k127_3387640_1	511051.CSE_11670	4.733e-118	400.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppF	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678	3.6.3.24	ko:K02031,ko:K02032,ko:K10823,ko:K10824,ko:K12372,ko:K13892	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00324,M00348,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.11,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iAPECO1_1312.APECO1_362,iEC042_1314.EC042_1615,iEC042_1314.EC042_3846,iECABU_c1320.ECABU_c39820,iECED1_1282.ECED1_4219,iECH74115_1262.ECH74115_2095,iECOK1_1307.ECOK1_1402,iECS88_1305.ECS88_1315,iECSP_1301.ECSP_1968,iECUMN_1333.ECUMN_1737,iECW_1372.ECW_m1611,iECs_1301.ECs2087,iEKO11_1354.EKO11_2337,iPC815.YPO3999,iSF_1195.SF3575,iSFxv_1172.SFxv_3897,iS_1188.S4195,iUMN146_1321.UM146_10835,iUTI89_1310.UTI89_C1445,iWFL_1372.ECW_m1611,iZ_1308.Z2227,ic_1306.c4355	ABC_tran,oligo_HPY
SRR25158518_k127_3387640_6	765420.OSCT_0207	1.045e-79	290.0	COG0747@1|root,COG0747@2|Bacteria,2G85H@200795|Chloroflexi,3773I@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158518_k127_3387640_4	621372.ACIH01000143_gene211	1.102e-102	356.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158518_k127_3387640_3	709986.Deima_2413	6.255e-106	355.0	COG0601@1|root,COG0601@2|Bacteria,1WIGY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158518_k127_3387640_5	1293054.HSACCH_01410	9.016e-86	294.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WB1B@53433|Halanaerobiales	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
SRR25158518_k127_3387640_2	1128421.JAGA01000002_gene833	2.746e-112	388.0	COG0444@1|root,COG0444@2|Bacteria,2NQAA@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158518_k127_3394694_2	383372.Rcas_3433	9.845e-25	118.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,375B1@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
SRR25158518_k127_3394694_1	471853.Bcav_1737	7.921e-29	126.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158518_k127_3394694_4	246194.CHY_0109	1.191e-18	94.0	COG3339@1|root,COG3339@2|Bacteria,1VQH0@1239|Firmicutes,24X4Z@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158518_k127_3394694_0	446462.Amir_4030	1.273e-45	169.0	COG4870@1|root,COG4870@2|Bacteria,2I4QS@201174|Actinobacteria,4E2KS@85010|Pseudonocardiales	201174|Actinobacteria	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SRR25158518_k127_3394694_5	1394178.AWOO02000010_gene4163	1.634e-17	96.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria,4EJZA@85012|Streptosporangiales	201174|Actinobacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158518_k127_3394694_3	485913.Krac_4159	1.184e-23	106.0	COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi	2|Bacteria	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3406582_8	1380346.JNIH01000031_gene1032	5.872e-61	215.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158518_k127_3406582_3	290397.Adeh_2467	5.066e-104	356.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2YU6X@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
SRR25158518_k127_3406582_2	1121468.AUBR01000026_gene2957	3.292e-134	447.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,42FJ7@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158518_k127_3406582_5	526225.Gobs_4770	2.94e-91	316.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4ERID@85013|Frankiales	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158518_k127_3406582_9	585531.HMPREF0063_12825	5.214e-12	78.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4DS4C@85009|Propionibacteriales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158518_k127_3406582_6	518766.Rmar_2306	1.016e-72	261.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158518_k127_3406582_0	1122611.KB903964_gene4915	2.555e-200	662.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,4EG13@85012|Streptosporangiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158518_k127_3406582_1	1123023.JIAI01000008_gene1621	1.825e-149	520.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DZFC@85010|Pseudonocardiales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158518_k127_3406582_4	1173028.ANKO01000106_gene363	1.47e-99	337.0	COG0150@1|root,COG0150@2|Bacteria,1G1WY@1117|Cyanobacteria,1H8GW@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158518_k127_3406582_7	1050202.KB913024_gene336	1.334e-63	245.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,407HV@622450|Actinopolysporales	201174|Actinobacteria	F	AICARFT/IMPCHase bienzyme	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158518_k127_3408515_2	1273125.Rrhod_3764	2.799e-18	92.0	COG0600@1|root,COG0600@2|Bacteria,2HDX7@201174|Actinobacteria,4FW72@85025|Nocardiaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158518_k127_3408515_0	1121918.ARWE01000001_gene385	1.224e-161	521.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WTRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
SRR25158518_k127_3408515_1	1125971.ASJB01000083_gene1686	4.582e-43	162.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4DXBU@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158518_k127_3432490_0	1380390.JIAT01000010_gene3879	5.444e-288	892.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CSGY@84995|Rubrobacteria	84995|Rubrobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158518_k127_3432490_3	765420.OSCT_1231	1.829e-103	356.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi,37587@32061|Chloroflexia	200795|Chloroflexi	KT	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
SRR25158518_k127_3432490_4	644966.Tmar_1104	1.374e-23	116.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SRR25158518_k127_3432490_2	671143.DAMO_1028	2.63e-112	384.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47,6.1.1.16	ko:K01883,ko:K12339,ko:K21148	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859,R10610	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	PALP,tRNA-synt_1e
SRR25158518_k127_3432490_5	929712.KI912613_gene4710	4.954e-21	108.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CTFG@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158518_k127_3432490_1	485913.Krac_6683	9.382e-143	464.0	COG0476@1|root,COG0476@2|Bacteria,2G5TN@200795|Chloroflexi	200795|Chloroflexi	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158518_k127_3435203_5	1128421.JAGA01000002_gene445	2.775e-07	63.0	COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria	2|Bacteria	G	MutL protein	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
SRR25158518_k127_3435203_2	370438.PTH_2212	1.272e-28	133.0	COG2110@1|root,COG2755@1|root,COG2110@2|Bacteria,COG2755@2|Bacteria,1VDE2@1239|Firmicutes,24N6X@186801|Clostridia,262J2@186807|Peptococcaceae	186801|Clostridia	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158518_k127_3435203_1	867903.ThesuDRAFT_02308	2.972e-58	229.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WCG8@538999|Clostridiales incertae sedis	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158518_k127_3435203_0	552811.Dehly_0249	1.35e-59	228.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,34D4S@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SRR25158518_k127_3435203_3	1382356.JQMP01000003_gene2543	7.896e-28	119.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi,27YDS@189775|Thermomicrobia	189775|Thermomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158518_k127_3435203_4	1382306.JNIM01000001_gene275	1.04e-17	83.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
SRR25158518_k127_346960_2	1496688.ER33_07135	4.148e-71	241.0	COG3119@1|root,COG3119@2|Bacteria,1G22U@1117|Cyanobacteria,22RRC@167375|Cyanobium	1117|Cyanobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158518_k127_346960_1	216594.MMAR_1232	4.966e-111	363.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	atsB	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
SRR25158518_k127_346960_0	43759.JNWK01000085_gene6817	8.086e-190	603.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	aslB	GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
SRR25158518_k127_346960_3	944481.JAFP01000001_gene1185	2.328e-12	72.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2M7EG@213113|Desulfurellales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158518_k127_346960_4	670487.Ocepr_1405	1.196e-06	60.0	COG1295@1|root,COG1295@2|Bacteria,1WIGF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158518_k127_3480915_5	645991.Sgly_2433	1.081e-07	59.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,25ZY0@186807|Peptococcaceae	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158518_k127_3480915_2	682795.AciX8_4439	4.755e-41	156.0	COG0537@1|root,COG0537@2|Bacteria,3Y542@57723|Acidobacteria,2JJT8@204432|Acidobacteriia	204432|Acidobacteriia	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SRR25158518_k127_3480915_1	1394178.AWOO02000010_gene4222	1.265e-44	166.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria,4EPAK@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
SRR25158518_k127_3480915_0	485913.Krac_12111	1.888e-97	353.0	COG1022@1|root,COG1022@2|Bacteria,2G5S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158518_k127_3480915_4	525904.Tter_1056	4.194e-13	83.0	COG0828@1|root,COG0828@2|Bacteria,2NQ1U@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S21	rpsU	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158518_k127_3480915_3	1321786.HMPREF1992_01562	2.232e-36	143.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4H4MK@909932|Negativicutes	909932|Negativicutes	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158518_k127_3480915_6	1487953.JMKF01000011_gene5979	2.506e-06	60.0	COG1480@1|root,COG1480@2|Bacteria,1G1UW@1117|Cyanobacteria,1H8GK@1150|Oscillatoriales	1117|Cyanobacteria	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SRR25158518_k127_3489823_3	316067.Geob_3236	4.177e-53	203.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
SRR25158518_k127_3489823_1	1380390.JIAT01000010_gene4475	4.489e-67	243.0	COG3214@1|root,COG3214@2|Bacteria,2HPYW@201174|Actinobacteria,4CRE6@84995|Rubrobacteria	84995|Rubrobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158518_k127_3489823_4	446468.Ndas_1013	4.514e-24	117.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4EMHA@85012|Streptosporangiales	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158518_k127_3489823_7	504487.JCM19302_3548	0.0001824	54.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HZ70@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158518_k127_3489823_2	1242864.D187_000281	4.981e-62	230.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,42WQU@68525|delta/epsilon subdivisions,2WTEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158518_k127_3489823_5	298654.FraEuI1c_5729	3.713e-20	97.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4ESTA@85013|Frankiales	201174|Actinobacteria	K	PFAM sigma-70 region 2 domain protein	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_3489823_0	326427.Cagg_2096	5.685e-111	363.0	COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi,374SG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158518_k127_3498740_3	1297569.MESS2_1340012	8.842e-113	388.0	COG1082@1|root,COG1082@2|Bacteria,1PKSR@1224|Proteobacteria,2U1RX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158518_k127_3498740_2	314256.OG2516_05468	7.172e-138	449.0	COG0673@1|root,COG0673@2|Bacteria,1MVVF@1224|Proteobacteria,2TR6B@28211|Alphaproteobacteria,2PD91@252301|Oceanicola	28211|Alphaproteobacteria	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158518_k127_3498740_1	928724.SacglDRAFT_01700	2.391e-142	464.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4E1BC@85010|Pseudonocardiales	201174|Actinobacteria	GK	Transcriptional regulator sugar kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
SRR25158518_k127_3498740_4	644966.Tmar_0587	7.34e-44	169.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WD8Z@538999|Clostridiales incertae sedis	186801|Clostridia	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
SRR25158518_k127_3498740_0	383372.Rcas_2755	2.069e-180	574.0	COG0673@1|root,COG0673@2|Bacteria,2G7UY@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158518_k127_3498740_5	436308.Nmar_0408	1.476e-13	73.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158518_k127_3504701_2	479434.Sthe_1318	3.065e-41	161.0	COG0652@1|root,COG0652@2|Bacteria,2G6RE@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158518_k127_3504701_4	1285586.H131_09523	1.235e-23	116.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3IWBN@400634|Lysinibacillus	91061|Bacilli	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
SRR25158518_k127_3504701_5	41431.PCC8801_0331	1.521e-23	117.0	COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,3KGXW@43988|Cyanothece	1117|Cyanobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158518_k127_3504701_1	555088.DealDRAFT_2079	2.544e-74	272.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_3504701_0	292459.STH2403	4.216e-92	316.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes	1239|Firmicutes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158518_k127_3504701_7	446468.Ndas_3323	3.068e-07	63.0	COG0330@1|root,COG0330@2|Bacteria,2GNWU@201174|Actinobacteria,4EH8R@85012|Streptosporangiales	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158518_k127_3504701_3	326427.Cagg_0749	1.011e-36	161.0	COG0628@1|root,COG0628@2|Bacteria,2G712@200795|Chloroflexi,375FE@32061|Chloroflexia	32061|Chloroflexia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_3504701_8	1122925.KB895387_gene2807	3.286e-06	52.0	2DREZ@1|root,33BFB@2|Bacteria,1UPXP@1239|Firmicutes,4IVCS@91061|Bacilli,2743X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3504701_6	42256.RradSPS_2370	8.08e-20	104.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4CTMV@84995|Rubrobacteria	84995|Rubrobacteria	M	Capsule synthesis protein, CapA	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158518_k127_3512690_2	1449126.JQKL01000012_gene3514	3.984e-55	203.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,267ZX@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158518_k127_3512690_1	1031288.AXAA01000005_gene2057	4.956e-128	420.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,36E7R@31979|Clostridiaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158518_k127_3512690_0	266117.Rxyl_0956	1.018e-194	629.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4CTI3@84995|Rubrobacteria	84995|Rubrobacteria	EU	PFAM peptidase S9, prolyl oligopeptidase active site	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158518_k127_3512690_3	591158.SSMG_00143	1.559e-06	53.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria	201174|Actinobacteria	CG	Glycosyltransferase, MGT family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158518_k127_3514410_0	1122622.ATWJ01000010_gene1174	8.448e-76	264.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4FETP@85021|Intrasporangiaceae	201174|Actinobacteria	L	recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158518_k127_3514410_1	765420.OSCT_1250	4.859e-33	140.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi,375QN@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR25158518_k127_3532676_1	1445613.JALM01000138_gene3345	3.606e-134	433.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4E1GQ@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
SRR25158518_k127_3532676_4	345341.KUTG_03654	1.231e-14	82.0	28UGN@1|root,2ZGMH@2|Bacteria,2IT7C@201174|Actinobacteria,4ECG7@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3532676_0	543632.JOJL01000025_gene2223	9.266e-163	531.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DBNS@85008|Micromonosporales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141	ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667	RC00075	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158518_k127_3532676_2	485913.Krac_2428	5.172e-68	262.0	COG1609@1|root,COG1609@2|Bacteria,2G8EJ@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158518_k127_3532676_3	365044.Pnap_3437	6.313e-33	148.0	COG0329@1|root,COG0329@2|Bacteria,1MWAH@1224|Proteobacteria,2VH30@28216|Betaproteobacteria,4AD2X@80864|Comamonadaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158518_k127_3532676_5	649638.Trad_2793	3.409e-11	76.0	COG1028@1|root,COG1028@2|Bacteria,1WJBN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158518_k127_3536974_2	649638.Trad_2961	2.32e-19	91.0	COG0366@1|root,COG0366@2|Bacteria,1WIU5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM alpha amylase, catalytic	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
SRR25158518_k127_3536974_0	1279009.ADICEAN_03140	2.691e-134	447.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MR6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Alpha amylase, catalytic	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,BACON
SRR25158518_k127_3536974_1	867845.KI911784_gene2328	1.256e-43	161.0	COG0395@1|root,COG3833@1|root,COG0395@2|Bacteria,COG3833@2|Bacteria,2G8IJ@200795|Chloroflexi,3772H@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
SRR25158518_k127_3538636_2	1121472.AQWN01000005_gene2392	3.613e-53	202.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,260TT@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158518_k127_3538636_1	1200792.AKYF01000011_gene3732	1.825e-57	224.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
SRR25158518_k127_3538636_0	196162.Noca_3291	1.83e-58	229.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4DMZ2@85009|Propionibacteriales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158518_k127_3538812_0	566461.SSFG_07301	3.276e-23	107.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	1.14.13.9,4.1.1.105,4.1.1.28	ko:K00486,ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00038,M00042	R00685,R00699,R00736,R01960,R02080,R02701,R04909	RC00046,RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158518_k127_3563295_5	326427.Cagg_1607	7.493e-54	194.0	COG1666@1|root,COG1666@2|Bacteria,2G6TD@200795|Chloroflexi,375J1@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158518_k127_3563295_2	649747.HMPREF0083_05891	4.465e-110	381.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26QWN@186822|Paenibacillaceae	91061|Bacilli	E	acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158518_k127_3563295_7	105420.BBPO01000130_gene4737	1.779e-16	88.0	COG3502@1|root,COG3502@2|Bacteria,2I1TP@201174|Actinobacteria,2NJ64@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
SRR25158518_k127_3563295_1	1169154.KB897780_gene2333	5.314e-139	457.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158518_k127_3563295_6	1385520.N802_07670	3.576e-33	141.0	2EA9M@1|root,334E1@2|Bacteria,2I49S@201174|Actinobacteria	201174|Actinobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158518_k127_3563295_0	2002.JOEQ01000044_gene808	1.2e-162	528.0	COG0477@1|root,COG2814@2|Bacteria,2I3GZ@201174|Actinobacteria,4EGFI@85012|Streptosporangiales	201174|Actinobacteria	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_3563295_8	929712.KI912613_gene3718	3.452e-05	55.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4CU2M@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SRR25158518_k127_3563295_4	649638.Trad_2902	1.112e-80	299.0	COG0477@1|root,COG2814@2|Bacteria,1WJAR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SRR25158518_k127_3563295_3	208444.JNYY01000003_gene1775	1.642e-104	353.0	COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4DZMT@85010|Pseudonocardiales	201174|Actinobacteria	EGP	arabinose efflux permease	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
SRR25158518_k127_3564003_0	1235801.C822_01087	3.762e-88	303.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158518_k127_3564003_1	526225.Gobs_1791	1.235e-66	239.0	COG0702@1|root,COG0702@2|Bacteria,2ICEY@201174|Actinobacteria	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158518_k127_3564003_3	1502852.FG94_03584	9.895e-06	55.0	2ARCD@1|root,31GNE@2|Bacteria,1P9FI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3564003_2	867903.ThesuDRAFT_02290	1.973e-20	91.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WCFF@538999|Clostridiales incertae sedis	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158518_k127_3575321_3	1123320.KB889629_gene7803	5.726e-63	221.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria	201174|Actinobacteria	GK	polyphosphate glucokinase	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158518_k127_3575321_5	713586.KB900536_gene1543	1.622e-53	202.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,1S2EP@1236|Gammaproteobacteria,1WZIK@135613|Chromatiales	135613|Chromatiales	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_6
SRR25158518_k127_3575321_0	1035308.AQYY01000001_gene2445	1.824e-101	352.0	COG1226@1|root,COG1226@2|Bacteria,1V2CY@1239|Firmicutes,24DT6@186801|Clostridia,260Z7@186807|Peptococcaceae	186801|Clostridia	P	PFAM TrkA-N domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158518_k127_3575321_1	1279038.KB907344_gene3593	1.321e-99	347.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2JPD8@204441|Rhodospirillales	204441|Rhodospirillales	P	TrkA-N domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158518_k127_3575321_9	1121344.JHZO01000006_gene1873	1.758e-16	87.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158518_k127_3575321_6	292459.STH2026	1.866e-41	161.0	COG1051@1|root,COG1051@2|Bacteria,1V466@1239|Firmicutes,24PBY@186801|Clostridia	186801|Clostridia	F	PFAM NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
SRR25158518_k127_3575321_7	1123229.AUBC01000001_gene1837	3.078e-29	131.0	2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,2U8C9@28211|Alphaproteobacteria,3JZ9V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3575321_4	330214.NIDE3965	1.179e-56	203.0	COG0041@1|root,COG0041@2|Bacteria,3J0P8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158518_k127_3575321_2	292459.STH1807	8.823e-86	306.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,24ASU@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
SRR25158518_k127_3575321_8	1206744.BAGL01000055_gene1488	4.945e-25	115.0	COG0500@1|root,COG2226@2|Bacteria,2I7UQ@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3583429_3	1382356.JQMP01000003_gene1423	1.571e-43	181.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158518_k127_3583429_0	525904.Tter_0782	8.812e-95	337.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158518_k127_3583429_1	1449126.JQKL01000028_gene2598	1.021e-81	285.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex,PGPGW
SRR25158518_k127_3583429_5	485913.Krac_10837	0.0003357	53.0	COG0730@1|root,COG4272@1|root,COG0730@2|Bacteria,COG4272@2|Bacteria,2G6ZH@200795|Chloroflexi	200795|Chloroflexi	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	DUF1634,TauE
SRR25158518_k127_3583429_2	525909.Afer_1672	2.823e-46	179.0	COG0730@1|root,COG0730@2|Bacteria,2HGFT@201174|Actinobacteria,4CNDC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158518_k127_3583429_4	525904.Tter_0780	1.009e-24	106.0	COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400	-	-	-	Ribosomal_S18
SRR25158518_k127_3611003_0	326427.Cagg_0414	1.284e-119	391.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi,374YM@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the argininosuccinate synthase family. Type	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158518_k127_3611003_3	471852.Tcur_0639	4.59e-09	70.0	COG3147@1|root,COG3147@2|Bacteria,2ID4R@201174|Actinobacteria,4EHHH@85012|Streptosporangiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3611003_1	649831.L083_3664	1.536e-44	181.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	yflN	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158518_k127_3611003_2	426355.Mrad2831_2632	2.572e-13	78.0	2EMWV@1|root,33FJ4@2|Bacteria,1NI97@1224|Proteobacteria,2UJMC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3612281_6	123899.JPQP01000017_gene2392	2.09e-11	65.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,3T2HT@506|Alcaligenaceae	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158518_k127_3612281_3	926550.CLDAP_41140	1.883e-72	256.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158518_k127_3612281_5	555088.DealDRAFT_2408	7.658e-35	149.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia,42K23@68298|Syntrophomonadaceae	186801|Clostridia	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158518_k127_3612281_0	1121346.KB899808_gene3514	1.115e-103	351.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158518_k127_3612281_4	525904.Tter_1705	3.869e-58	219.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	3.4.21.107	ko:K04771,ko:K11749,ko:K16922	ko01503,ko02020,ko02024,ko04112,map01503,map02020,map02024,map04112	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158518_k127_3612281_2	861299.J421_1297	2.217e-80	282.0	COG0821@1|root,COG0821@2|Bacteria,1ZST3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158518_k127_3612281_1	644966.Tmar_1012	2.367e-90	300.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WCC9@538999|Clostridiales incertae sedis	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
SRR25158518_k127_3619923_1	1254432.SCE1572_40010	4.617e-51	207.0	COG0642@1|root,COG0784@1|root,COG2770@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X83K@28221|Deltaproteobacteria,2YUDP@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
SRR25158518_k127_3619923_0	1297742.A176_02196	2.613e-63	246.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X75B@28221|Deltaproteobacteria,2Z3G9@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg
SRR25158518_k127_3631583_8	118166.JH976537_gene4234	3.918e-13	83.0	COG3211@1|root,COG4222@1|root,COG3211@2|Bacteria,COG4222@2|Bacteria,1GQ3P@1117|Cyanobacteria,1HI0H@1150|Oscillatoriales	1117|Cyanobacteria	Q	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Alk_phosphatase,Exo_endo_phos,GDPD,HemolysinCabind,Phytase-like
SRR25158518_k127_3631583_9	1463853.JOHW01000008_gene986	1.028e-08	64.0	2BD7Q@1|root,326VU@2|Bacteria,2HCFH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3631583_4	1121946.AUAX01000023_gene4182	3.397e-70	246.0	COG0596@1|root,COG0596@2|Bacteria,2GJ4I@201174|Actinobacteria,4DM56@85008|Micromonosporales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158518_k127_3631583_0	1274.HX89_10750	1.278e-118	387.0	COG0647@1|root,COG0647@2|Bacteria,2GJG6@201174|Actinobacteria,1ZWGS@145357|Dermacoccaceae	201174|Actinobacteria	G	Belongs to the HAD-like hydrolase superfamily	nagD	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158518_k127_3631583_6	211114.JOEF01000033_gene1151	7.193e-41	161.0	COG1075@1|root,COG1075@2|Bacteria,2HS4E@201174|Actinobacteria,4ECBM@85010|Pseudonocardiales	201174|Actinobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3631583_7	525904.Tter_2060	3.298e-30	140.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,fn3
SRR25158518_k127_3631583_3	1219375.CM002139_gene1309	7.425e-76	287.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X484@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,PPC,P_proprotein,Peptidase_S8
SRR25158518_k127_3631583_2	1128421.JAGA01000002_gene860	4.915e-109	363.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158518_k127_3631583_5	35754.JNYJ01000038_gene5071	1.024e-42	162.0	COG0640@1|root,COG0640@2|Bacteria,2IM9G@201174|Actinobacteria,4DJC7@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24
SRR25158518_k127_3631583_1	1245475.ANAE01000092_gene397	2.843e-116	388.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4ENDZ@85012|Streptosporangiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158518_k127_363529_0	646529.Desaci_3659	4.382e-81	285.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158518_k127_363529_1	1262915.BN574_00404	6.743e-13	69.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4H5MV@909932|Negativicutes	909932|Negativicutes	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158518_k127_3638015_3	479434.Sthe_3123	3.504e-51	184.0	COG2376@1|root,COG2376@2|Bacteria,2G80E@200795|Chloroflexi,27Z3H@189775|Thermomicrobia	189775|Thermomicrobia	G	Dak1 domain	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
SRR25158518_k127_3638015_2	1484479.DI14_05110	1.167e-93	317.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3WERW@539002|Bacillales incertae sedis	91061|Bacilli	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
SRR25158518_k127_3638015_6	1184609.KILIM_042_00260	3.805e-40	164.0	COG1461@1|root,COG2376@1|root,COG1461@2|Bacteria,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4F6MZ@85018|Dermatophilaceae	201174|Actinobacteria	G	Dak1 domain	dhaK	-	2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	M00344	R01011,R01012,R01059	RC00002,RC00015,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Dak1
SRR25158518_k127_3638015_9	1382356.JQMP01000001_gene1271	1.704e-20	96.0	COG3412@1|root,COG3412@2|Bacteria,2GAUU@200795|Chloroflexi,27Z9J@189775|Thermomicrobia	189775|Thermomicrobia	S	PTS system fructose IIA component	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
SRR25158518_k127_3638015_7	2074.JNYD01000006_gene1763	1.915e-39	163.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4E2P5@85010|Pseudonocardiales	201174|Actinobacteria	S	Dihydroxyacetone kinase	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158518_k127_3638015_4	867845.KI911784_gene1702	3.923e-46	189.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,3754U@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
SRR25158518_k127_3638015_5	518766.Rmar_0987	6.536e-45	178.0	COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,1FK2H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_3638015_0	255470.cbdbA765	1.603e-168	542.0	COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,34D2R@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158518_k127_3638015_8	1380356.JNIK01000015_gene2546	5.038e-23	109.0	2BPDR@1|root,32I5V@2|Bacteria,2H6IS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3638015_1	1121396.KB893079_gene845	1.475e-165	532.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MHYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SRR25158518_k127_3648823_0	266117.Rxyl_0133	1.893e-174	567.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158518_k127_3648823_2	324602.Caur_0726	2e-25	113.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
SRR25158518_k127_3648823_1	479434.Sthe_2652	2.303e-136	446.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi,27Y13@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158518_k127_3658333_0	452637.Oter_4614	3.587e-172	563.0	COG3590@1|root,COG3590@2|Bacteria,46UUX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Peptidase family M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
SRR25158518_k127_3658333_1	502025.Hoch_4942	1.464e-53	211.0	2DM58@1|root,31S4C@2|Bacteria,1RGAH@1224|Proteobacteria,431QP@68525|delta/epsilon subdivisions,2WWXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3668028_4	1123288.SOV_5c00070	5.983e-13	72.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H597@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158518_k127_3668028_1	1449353.JQMQ01000005_gene5310	1.095e-138	466.0	COG1501@1|root,COG1501@2|Bacteria,2IDV6@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3668028_0	1051632.TPY_3790	4.225e-149	485.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,3WCDU@538999|Clostridiales incertae sedis	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158518_k127_3668028_2	479434.Sthe_3477	4.156e-112	375.0	COG1071@1|root,COG1071@2|Bacteria,2GAC3@200795|Chloroflexi,27Z5H@189775|Thermomicrobia	189775|Thermomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158518_k127_3668028_3	1051632.TPY_3787	3.027e-70	258.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,249UD@186801|Clostridia	186801|Clostridia	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158518_k127_3687428_0	1283299.AUKG01000001_gene2831	7.86e-128	419.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CS29@84995|Rubrobacteria	84995|Rubrobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158518_k127_3687428_1	1380390.JIAT01000011_gene2751	6.587e-67	254.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CRYP@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158518_k127_3687428_2	358823.DF19_41010	4.09e-41	173.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA_2
SRR25158518_k127_3691009_1	1313172.YM304_13240	7.475e-143	467.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria	201174|Actinobacteria	F	Pfam Amidohydrolase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158518_k127_3691009_5	255470.cbdbA1030	0.0004583	52.0	2EN6D@1|root,33FU8@2|Bacteria,2GATE@200795|Chloroflexi,34DB0@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3691009_3	1089553.Tph_c04840	1.432e-51	196.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_3691009_4	1128421.JAGA01000003_gene3536	1.063e-47	193.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158518_k127_3691009_0	469371.Tbis_2750	1.515e-181	585.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DZRD@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd-type quinol oxidase, subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158518_k127_3691009_2	408672.NBCG_02623	1.611e-119	390.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4DN35@85009|Propionibacteriales	201174|Actinobacteria	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158518_k127_3694043_0	484770.UFO1_2708	1.003e-87	299.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158518_k127_3694043_1	765420.OSCT_0969	7.358e-53	207.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,374X2@32061|Chloroflexia	32061|Chloroflexia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SRR25158518_k127_3701617_3	1121362.A605_00860	8.25e-25	120.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,22JWI@1653|Corynebacteriaceae	201174|Actinobacteria	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_3701617_0	562970.Btus_0661	6.047e-239	770.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,2783N@186823|Alicyclobacillaceae	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158518_k127_3701617_2	479434.Sthe_3033	1.137e-49	183.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158518_k127_3701617_1	1298863.AUEP01000012_gene3662	3.264e-52	190.0	COG4894@1|root,COG4894@2|Bacteria,2GKWI@201174|Actinobacteria,4DUPV@85009|Propionibacteriales	201174|Actinobacteria	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
SRR25158518_k127_3703659_0	1382356.JQMP01000001_gene818	0.0	1090.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158518_k127_3703659_5	1380394.JADL01000003_gene5092	2.265e-25	113.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,2JTBQ@204441|Rhodospirillales	204441|Rhodospirillales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158518_k127_3703659_2	429009.Adeg_1604	5.888e-79	284.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158518_k127_3703659_3	1382356.JQMP01000003_gene1307	1.521e-46	184.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi,27XXM@189775|Thermomicrobia	189775|Thermomicrobia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158518_k127_3703659_1	562970.Btus_1420	6.878e-140	476.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,27835@186823|Alicyclobacillaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SRR25158518_k127_3703659_4	452637.Oter_3300	1.078e-39	172.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SRR25158518_k127_3703671_10	309801.trd_0203	4.928e-07	59.0	2A40S@1|root,30SJA@2|Bacteria,2GADS@200795|Chloroflexi,27YNA@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3703671_4	316274.Haur_3807	4.543e-62	225.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi,375M7@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158518_k127_3703671_0	1128421.JAGA01000002_gene682	1.996e-140	457.0	COG0214@1|root,COG0214@2|Bacteria,2NNZ6@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158518_k127_3703671_7	479431.Namu_3405	2.005e-38	166.0	COG5579@1|root,COG5579@2|Bacteria,2IM9J@201174|Actinobacteria,4ESX5@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
SRR25158518_k127_3703671_9	744979.R2A130_1194	1.802e-13	83.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2U2X2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2
SRR25158518_k127_3703671_6	525904.Tter_1713	9.19e-53	203.0	COG1680@1|root,COG1680@2|Bacteria,2NRI6@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158518_k127_3703671_5	316274.Haur_4220	2.962e-59	211.0	COG1403@1|root,COG1403@2|Bacteria,2G6WV@200795|Chloroflexi,375TQ@32061|Chloroflexia	32061|Chloroflexia	L	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158518_k127_3703671_2	867903.ThesuDRAFT_00371	2.712e-99	343.0	COG0617@1|root,COG2254@1|root,COG0617@2|Bacteria,COG2254@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WCIJ@538999|Clostridiales incertae sedis	186801|Clostridia	J	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SRR25158518_k127_3703671_11	741091.Rahaq_2154	4.438e-06	59.0	COG0457@1|root,COG3118@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,1MVB8@1224|Proteobacteria,1RPSN@1236|Gammaproteobacteria,3FH6E@34037|Rahnella	1236|Gammaproteobacteria	O	cellulose synthase	bcsC	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_8
SRR25158518_k127_3703671_1	575606.HMPREF0525_00817	2.111e-101	346.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158518_k127_3703671_3	1128421.JAGA01000002_gene1840	9.766e-76	277.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22,MFS_1
SRR25158518_k127_3703671_12	105425.BBPL01000014_gene2682	4.143e-05	54.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,2NFU6@228398|Streptacidiphilus	201174|Actinobacteria	L	ATP dependent DNA ligase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158518_k127_3703671_8	909663.KI867151_gene3008	4.705e-24	109.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria,2MR35@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR25158518_k127_3715870_2	485913.Krac_6683	5.708e-26	115.0	COG0476@1|root,COG0476@2|Bacteria,2G5TN@200795|Chloroflexi	200795|Chloroflexi	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158518_k127_3715870_1	867845.KI911784_gene3040	1.896e-40	153.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi,37783@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158518_k127_3715870_0	485913.Krac_8822	4.222e-132	427.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158518_k127_3717632_1	543632.JOJL01000026_gene2371	3.656e-85	288.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DCE9@85008|Micromonosporales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158518_k127_3717632_11	1479237.JMLY01000001_gene3491	8.014e-09	65.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,1S5Y8@1236|Gammaproteobacteria,46DJJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158518_k127_3717632_8	1268303.RHODMAR_4651	1.416e-24	120.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4G2IE@85025|Nocardiaceae	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4
SRR25158518_k127_3717632_0	479434.Sthe_2399	6.973e-90	305.0	COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,27XQF@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158518_k127_3717632_12	1463861.JNXE01000019_gene6050	3.037e-05	57.0	COG0500@1|root,COG2226@2|Bacteria,2IAGR@201174|Actinobacteria	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158518_k127_3717632_4	357808.RoseRS_0390	2.308e-78	284.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,375AU@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158518_k127_3717632_3	204669.Acid345_1338	1.718e-79	280.0	COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria,2JHRI@204432|Acidobacteriia	204432|Acidobacteriia	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158518_k127_3717632_5	1267534.KB906756_gene667	8.34e-78	288.0	COG0642@1|root,COG2199@1|root,COG2203@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PilZ,Response_reg,Y_Y_Y
SRR25158518_k127_3717632_9	56110.Oscil6304_3363	5.53e-19	102.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
SRR25158518_k127_3717632_7	459495.SPLC1_S051580	7.291e-41	166.0	COG0745@1|root,COG0745@2|Bacteria,1G5XG@1117|Cyanobacteria,1HB6Y@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158518_k127_3717632_2	1048339.KB913029_gene3267	5.543e-81	299.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4EVWG@85013|Frankiales	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
SRR25158518_k127_3717632_6	1380390.JIAT01000013_gene6	8.734e-62	225.0	COG3836@1|root,COG3836@2|Bacteria,2HGEA@201174|Actinobacteria,4CTKV@84995|Rubrobacteria	84995|Rubrobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
SRR25158518_k127_3717632_10	272557.APE_1838.1	2.31e-14	80.0	COG0517@1|root,arCOG00606@2157|Archaea,2XR4V@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158518_k127_3748083_0	525904.Tter_2549	1.161e-33	146.0	COG3850@1|root,COG3850@2|Bacteria,2NS42@2323|unclassified Bacteria	2|Bacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
SRR25158518_k127_3748083_1	479434.Sthe_0152	4.509e-13	82.0	COG2132@1|root,COG2132@2|Bacteria,2G8IH@200795|Chloroflexi,27YH6@189775|Thermomicrobia	189775|Thermomicrobia	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_3
SRR25158518_k127_3758976_2	485913.Krac_2637	3.889e-84	287.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158518_k127_3758976_5	1177594.MIC448_2190012	2.918e-39	163.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158518_k127_3758976_7	1449058.JQKT01000009_gene191	7.972e-36	154.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158518_k127_3758976_8	1449058.JQKT01000009_gene191	3.839e-30	138.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158518_k127_3758976_9	1449058.JQKT01000009_gene191	5.517e-29	132.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158518_k127_3758976_6	1449058.JQKT01000009_gene191	1.517e-37	156.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158518_k127_3758976_1	485913.Krac_2635	1.341e-125	438.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
SRR25158518_k127_3758976_4	1242864.D187_000281	8.773e-47	187.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,42WQU@68525|delta/epsilon subdivisions,2WTEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158518_k127_3758976_3	309799.DICTH_1915	3.92e-68	260.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldE2	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158518_k127_3758976_0	515635.Dtur_0186	4.038e-157	508.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158518_k127_3769118_3	926569.ANT_18000	5.269e-12	70.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158518_k127_3769118_1	1122933.JNIY01000010_gene1297	2.462e-41	164.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4F2SF@85016|Cellulomonadaceae	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SRR25158518_k127_3769118_2	926550.CLDAP_23690	2.325e-25	117.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158518_k127_3769118_4	237368.SCABRO_00546	0.0007604	49.0	COG2442@1|root,COG2442@2|Bacteria,2J4DY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158518_k127_3769118_0	926554.KI912669_gene5027	1.425e-73	266.0	COG4805@1|root,COG4805@2|Bacteria,1WM4J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3775809_2	1158345.JNLL01000001_gene1734	6.244e-109	362.0	COG0191@1|root,COG0191@2|Bacteria,2G3VP@200783|Aquificae	200783|Aquificae	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158518_k127_3775809_0	479434.Sthe_3486	3.501e-191	623.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3775809_1	309801.trd_A0505	5.746e-188	600.0	COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
SRR25158518_k127_3775809_3	1336243.JAEA01000001_gene1662	1.563e-36	142.0	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2U9DU@28211|Alphaproteobacteria,1JVSX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158518_k127_3783672_2	1128421.JAGA01000003_gene3009	5.76e-72	256.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,SGL,VCBS
SRR25158518_k127_3783672_4	494419.ALPM01000017_gene627	6.068e-34	145.0	COG0628@1|root,COG0628@2|Bacteria,2GM01@201174|Actinobacteria,1W9BS@1268|Micrococcaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_3783672_6	1448389.BAVQ01000013_gene4022	4.964e-25	113.0	2BF47@1|root,328WE@2|Bacteria,2IM74@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
SRR25158518_k127_3783672_3	1444711.CCJF01000005_gene357	2.109e-40	161.0	2C3WA@1|root,2Z8P1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158518_k127_3783672_0	1242864.D187_006998	4.159e-96	346.0	COG4188@1|root,COG4188@2|Bacteria,1Q4K6@1224|Proteobacteria,42YYD@68525|delta/epsilon subdivisions,2WTU7@28221|Deltaproteobacteria,2Z2HI@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3783672_5	1078020.KEK_12978	2.865e-28	121.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,23A0D@1762|Mycobacteriaceae	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158518_k127_3783672_7	471852.Tcur_3874	2.319e-14	82.0	2E4AX@1|root,32Z6K@2|Bacteria,2GW4T@201174|Actinobacteria,4EJ1I@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
SRR25158518_k127_3783672_1	479434.Sthe_0351	2.699e-87	296.0	COG2761@1|root,COG2761@2|Bacteria,2G7EP@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
SRR25158518_k127_3786000_4	1121946.AUAX01000012_gene6528	7.281e-51	186.0	COG1309@1|root,COG1309@2|Bacteria,2IJNE@201174|Actinobacteria,4DDDQ@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158518_k127_3786000_2	1120960.ATXG01000009_gene60	1.514e-68	241.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria,4FNJ0@85023|Microbacteriaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158518_k127_3786000_5	1128421.JAGA01000002_gene486	1.538e-43	178.0	COG1381@1|root,COG1381@2|Bacteria,2NPV3@2323|unclassified Bacteria	2|Bacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158518_k127_3786000_7	1127134.NOCYR_0781	7.778e-29	130.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria,4G1T9@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158518_k127_3786000_1	1320556.AVBP01000012_gene3572	2.09e-111	381.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
SRR25158518_k127_3786000_11	1454202.PPBDW_130675___1	1.368e-14	78.0	COG1925@1|root,COG4668@1|root,COG1925@2|Bacteria,COG4668@2|Bacteria,1MVP6@1224|Proteobacteria,1RQP4@1236|Gammaproteobacteria,1XSJ1@135623|Vibrionales	135623|Vibrionales	G	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain	fruB	-	2.7.1.202	ko:K02768,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS-HPr,PTS_EIIA_2
SRR25158518_k127_3786000_8	1187851.A33M_2439	4.671e-28	127.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,3FD61@34008|Rhodovulum	28211|Alphaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
SRR25158518_k127_3786000_3	479434.Sthe_3107	1.63e-56	211.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158518_k127_3786000_12	350058.Mvan_1589	3.386e-08	61.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,23A0P@1762|Mycobacteriaceae	201174|Actinobacteria	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158518_k127_3786000_10	926569.ANT_27580	8.284e-20	102.0	COG2009@1|root,COG2009@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	ko:K00241,ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158518_k127_3786000_6	410359.Pcal_2128	1.319e-42	167.0	COG0479@1|root,arCOG00962@2157|Archaea,2XPRI@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SRR25158518_k127_3786000_0	883.DvMF_1126	1.095e-131	431.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2M8I0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
SRR25158518_k127_3786000_9	1521187.JPIM01000055_gene3646	4.398e-27	111.0	COG0247@1|root,COG0247@2|Bacteria,2G7VD@200795|Chloroflexi,3754W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
SRR25158518_k127_3794831_6	1449355.JQNR01000005_gene5327	6.441e-31	129.0	COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria	201174|Actinobacteria	K	asnC family	lrp_3	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158518_k127_3794831_7	309801.trd_1490	3.011e-22	106.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158518_k127_3794831_1	1304874.JAFY01000002_gene150	2.533e-80	287.0	COG1814@1|root,COG1814@2|Bacteria,3TBXB@508458|Synergistetes	508458|Synergistetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158518_k127_3794831_4	1121459.AQXE01000011_gene2396	1.162e-33	145.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MAJ3@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158518_k127_3794831_0	1267535.KB906767_gene3318	1.546e-93	327.0	COG0665@1|root,COG0665@2|Bacteria,3Y6FK@57723|Acidobacteria,2JKN4@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_3794831_3	588581.Cpap_0479	1.669e-37	154.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_3794831_2	312284.A20C1_07763	6.366e-60	215.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158518_k127_3794831_5	1077972.ARGLB_080_00250	1.285e-33	131.0	COG1670@1|root,COG1670@2|Bacteria,2IHXG@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferases including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158518_k127_3805940_3	1090318.ATTI01000001_gene2448	3.461e-32	134.0	COG4529@1|root,COG4529@2|Bacteria,1MU3U@1224|Proteobacteria,2TUBM@28211|Alphaproteobacteria,2K079@204457|Sphingomonadales	204457|Sphingomonadales	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
SRR25158518_k127_3805940_2	1246995.AFR_22380	3.499e-75	271.0	COG2334@1|root,COG2334@2|Bacteria,2I2JR@201174|Actinobacteria,4D9XM@85008|Micromonosporales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158518_k127_3805940_5	46234.ANA_C12039	4.587e-05	57.0	2AY0A@1|root,31Q1V@2|Bacteria,1G5XA@1117|Cyanobacteria,1HND8@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3805940_0	316274.Haur_4306	1.154e-126	432.0	COG2252@1|root,COG2252@2|Bacteria,2G7JW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158518_k127_3805940_1	243164.DET1429	1.358e-91	317.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,34CMZ@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158518_k127_3805940_4	31033.ENSTRUP00000012573	1.397e-10	64.0	COG0105@1|root,KOG0888@2759|Eukaryota,3A01M@33154|Opisthokonta,3BPJ3@33208|Metazoa,3D696@33213|Bilateria,48A2A@7711|Chordata,49731@7742|Vertebrata,4A39Y@7898|Actinopterygii	33208|Metazoa	F	Non-metastatic cells 4, protein expressed in	NME4	GO:0003674,GO:0003824,GO:0004550,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0008289,GO:0009116,GO:0009117,GO:0009132,GO:0009987,GO:0010876,GO:0010941,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0019866,GO:0019899,GO:0031090,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0033036,GO:0034641,GO:0042981,GO:0043067,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046483,GO:0046939,GO:0050789,GO:0050794,GO:0051020,GO:0051179,GO:0051234,GO:0055086,GO:0065007,GO:0070013,GO:0071702,GO:0071704,GO:1901135,GO:1901360,GO:1901564,GO:1901611,GO:1901612,GO:1901657	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158518_k127_3807804_4	880073.Calab_0133	1.492e-32	147.0	COG0860@1|root,COG1361@1|root,COG3858@1|root,COG0860@2|Bacteria,COG1361@2|Bacteria,COG3858@2|Bacteria,2NQII@2323|unclassified Bacteria	2|Bacteria	M	Glyco_18	-	-	3.4.17.14,3.5.1.28	ko:K01448,ko:K07260,ko:K20276	ko00550,ko01100,ko01502,ko01503,ko02020,ko02024,map00550,map01100,map01502,map01503,map02020,map02024	M00651,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,CHAP,CW_binding_2,Cu_amine_oxidN1,GBS_Bsp-like,Glyco_hydro_18,Glyco_hydro_25,Peptidase_C39_2,SH3_5,VanY,YSIRK_signal
SRR25158518_k127_3807804_5	596324.TREVI0001_0477	2.33e-17	97.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
SRR25158518_k127_3807804_3	1128421.JAGA01000002_gene1831	7.663e-37	153.0	COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	1.1.1.133,5.1.3.13,5.1.3.26	ko:K00067,ko:K01790,ko:K19997	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iECSF_1327.ECSF_1929,iEcHS_1320.EcHS_A2180,iJN678.rfbD	RmlD_sub_bind
SRR25158518_k127_3807804_1	66373.JOFQ01000002_gene5075	4.059e-112	379.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158518_k127_3807804_2	1211819.CALK01000054_gene1099	6.877e-58	214.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,3VNQI@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
SRR25158518_k127_3807804_6	1200557.JHWV01000001_gene447	4.698e-15	88.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4H2TV@909932|Negativicutes	909932|Negativicutes	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158518_k127_3807804_0	1382356.JQMP01000004_gene496	1.657e-112	370.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi,27XN7@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158518_k127_3844623_1	994479.GL877878_gene68	9.064e-31	121.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DZMS@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103,1.1.1.380	ko:K00060,ko:K08322	ko00040,ko00260,ko01100,map00040,map00260,map01100	-	R01465,R10848	RC00085,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158518_k127_3844623_0	997346.HMPREF9374_0644	1.825e-149	485.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,27B3G@186824|Thermoactinomycetaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158518_k127_3844623_2	1286171.EAL2_c02650	6.208e-09	67.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,25VDW@186806|Eubacteriaceae	186801|Clostridia	E	histidinol phosphate phosphatase, HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
SRR25158518_k127_3845212_1	1455608.JDTH01000001_gene3470	8.394e-06	56.0	COG1506@1|root,COG2319@1|root,arCOG01646@2157|Archaea,arCOG02491@2157|Archaea,2XWA1@28890|Euryarchaeota,23TRF@183963|Halobacteria	183963|Halobacteria	E	Peptidase S9 prolyl oligopeptidase active site	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRR25158518_k127_3845212_0	204669.Acid345_1270	2.547e-51	184.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158518_k127_3845417_4	1487953.JMKF01000025_gene2360	2.503e-31	123.0	COG0410@1|root,COG0410@2|Bacteria,1G1TN@1117|Cyanobacteria,1H996@1150|Oscillatoriales	1117|Cyanobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158518_k127_3845417_0	657322.FPR_21670	7.503e-68	240.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158518_k127_3845417_3	671143.DAMO_2813	2.362e-33	143.0	COG1102@1|root,COG1102@2|Bacteria,2NRB0@2323|unclassified Bacteria	2|Bacteria	F	Cytidylate kinase-like family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
SRR25158518_k127_3845417_6	926692.AZYG01000063_gene1193	2.312e-19	99.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WASA@53433|Halanaerobiales	186801|Clostridia	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158518_k127_3845417_5	1121346.KB899814_gene1835	2.518e-28	126.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,26QDI@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158518_k127_3845417_2	309801.trd_1481	3.425e-57	217.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi,27Y5S@189775|Thermomicrobia	189775|Thermomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SRR25158518_k127_3845417_1	479434.Sthe_2502	3.506e-58	213.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158518_k127_3850302_0	404589.Anae109_2754	2.734e-165	538.0	COG1148@1|root,COG1148@2|Bacteria,1PTJ7@1224|Proteobacteria,42NJN@68525|delta/epsilon subdivisions,2WJHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
SRR25158518_k127_3850302_1	1128421.JAGA01000002_gene59	1.079e-09	63.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158518_k127_3857051_1	1382306.JNIM01000001_gene3777	2.469e-96	333.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158518_k127_3857051_3	1449050.JNLE01000003_gene2228	9.306e-72	256.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_3857051_4	1382306.JNIM01000001_gene1969	1.836e-56	215.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	ogt	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AraC_binding,DNA_binding_1,Endonuclea_NS_2,HTH_18
SRR25158518_k127_3857051_5	452652.KSE_58620	7.332e-41	158.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,2M57Z@2063|Kitasatospora	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_3857051_8	408672.NBCG_03835	2.143e-18	97.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158518_k127_3857051_10	512565.AMIS_61740	2.986e-07	61.0	COG0454@1|root,COG0456@2|Bacteria,2I2W1@201174|Actinobacteria,4DD5J@85008|Micromonosporales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
SRR25158518_k127_3857051_11	1453496.AT03_03605	1.621e-06	58.0	COG0454@1|root,COG0456@2|Bacteria,1QEZN@1224|Proteobacteria,1S4IF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role	phnO	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019634,GO:0019637,GO:0033051,GO:0044237,GO:0044424,GO:0044464,GO:0071704,GO:1901564	-	ko:K09994	ko00440,map00440	-	R11479	RC00096	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
SRR25158518_k127_3857051_0	710685.MycrhN_3285	1.928e-109	370.0	COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,235R0@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	PFAM Lipopolysaccharide kinase (Kdo WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158518_k127_3857051_6	1120949.KB903314_gene344	6.751e-30	136.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158518_k127_3857051_7	765913.ThidrDRAFT_0326	4.363e-29	131.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,1RNS3@1236|Gammaproteobacteria,1WY2Y@135613|Chromatiales	135613|Chromatiales	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SRR25158518_k127_3857051_9	1336208.JADY01000011_gene3100	2.068e-07	63.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2TTX1@28211|Alphaproteobacteria,2JQDM@204441|Rhodospirillales	204441|Rhodospirillales	O	Tellurite resistance protein TerB	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
SRR25158518_k127_3857051_2	67267.JNXT01000014_gene278	2.591e-75	256.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
SRR25158518_k127_3858057_4	1298863.AUEP01000007_gene351	4.802e-05	47.0	COG1226@1|root,COG1226@2|Bacteria,2HZRR@201174|Actinobacteria,4DTS4@85009|Propionibacteriales	201174|Actinobacteria	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_N
SRR25158518_k127_3858057_1	1304865.JAGF01000001_gene2536	2.373e-99	342.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,2IETB@201174|Actinobacteria	201174|Actinobacteria	P	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
SRR25158518_k127_3858057_2	408672.NBCG_05380	4.387e-89	331.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4DP8S@85009|Propionibacteriales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158518_k127_3858057_3	379066.GAU_2901	1.732e-25	115.0	COG0125@1|root,COG0125@2|Bacteria,1ZUCV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
SRR25158518_k127_3858057_0	1449976.KALB_6351	1.673e-123	402.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4DX5F@85010|Pseudonocardiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158518_k127_386412_4	646529.Desaci_3470	2.465e-45	170.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,260Q8@186807|Peptococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158518_k127_386412_1	357808.RoseRS_0794	3.138e-110	383.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi,375DT@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158518_k127_386412_6	357808.RoseRS_3975	6.605e-18	99.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi,375A7@32061|Chloroflexia	32061|Chloroflexia	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
SRR25158518_k127_386412_5	1232436.CAPF01000004_gene233	1.12e-38	168.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CVFS@84998|Coriobacteriia	84998|Coriobacteriia	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
SRR25158518_k127_386412_3	926550.CLDAP_01110	4.768e-62	242.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158518_k127_386412_2	264732.Moth_1028	1.459e-64	236.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42HMW@68295|Thermoanaerobacterales	186801|Clostridia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158518_k127_386412_0	671143.DAMO_0060	9.087e-191	623.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168,ko:K07479	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158518_k127_3864438_0	1232410.KI421420_gene3185	3.244e-65	235.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,439YG@68525|delta/epsilon subdivisions,2WUBB@28221|Deltaproteobacteria,43UAD@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158518_k127_3864438_1	472175.EL18_00518	2.531e-05	54.0	COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158518_k127_3873912_3	485913.Krac_8438	1.048e-42	164.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158518_k127_3873912_0	1121472.AQWN01000007_gene1144	1.037e-112	394.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158518_k127_3873912_2	660470.Theba_0352	8.601e-79	274.0	COG3643@1|root,COG3643@2|Bacteria,2GC70@200918|Thermotogae	200918|Thermotogae	E	PFAM Formiminotransferase domain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158518_k127_3873912_5	1283299.AUKG01000001_gene2949	2.012e-17	89.0	COG3369@1|root,COG3369@2|Bacteria,2GQQQ@201174|Actinobacteria,4CTNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
SRR25158518_k127_3873912_1	1128421.JAGA01000003_gene2737	3.855e-105	355.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158518_k127_3873912_4	292459.STH3193	6.971e-35	134.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158518_k127_3907389_2	378806.STAUR_1272	5.686e-47	172.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158518_k127_3907389_1	926550.CLDAP_03560	2.876e-50	188.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158518_k127_3907389_0	1125863.JAFN01000001_gene2796	2.608e-121	412.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42PJ7@68525|delta/epsilon subdivisions,2WMEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
SRR25158518_k127_3907400_1	1051632.TPY_3786	9.501e-76	267.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,247Q5@186801|Clostridia	186801|Clostridia	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12,2.3.1.168,2.3.1.61	ko:K00627,ko:K00658,ko:K09699	ko00010,ko00020,ko00280,ko00310,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00310,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036,M00307	R00209,R02569,R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02742,RC02833,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,CMD,E3_binding
SRR25158518_k127_3907400_0	525904.Tter_0096	1.54e-109	365.0	COG0320@1|root,COG0320@2|Bacteria,2NNPI@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158518_k127_3907400_4	479432.Sros_7437	3.006e-22	112.0	COG3209@1|root,COG3534@1|root,COG3209@2|Bacteria,COG3534@2|Bacteria,2I35N@201174|Actinobacteria,4EIAW@85012|Streptosporangiales	201174|Actinobacteria	M	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158518_k127_3907400_5	105420.BBPO01000060_gene3281	4.209e-10	69.0	COG1595@1|root,COG1595@2|Bacteria,2IC8V@201174|Actinobacteria,2NIKR@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_3907400_2	529709.PYCH_05190	3.651e-35	147.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,242M3@183968|Thermococci	183968|Thermococci	S	gtp1 obg	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
SRR25158518_k127_3907400_3	404589.Anae109_2517	6.391e-28	116.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iSFV_1184.SFV_1640,iSF_1195.SF1648,iSFxv_1172.SFxv_1849,iS_1188.S1780	A_deaminase
SRR25158518_k127_3910748_3	311424.DhcVS_737	1.68e-49	181.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,34CWN@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158518_k127_3910748_4	479434.Sthe_1556	5.023e-44	174.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi,27Y6I@189775|Thermomicrobia	189775|Thermomicrobia	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
SRR25158518_k127_3910748_1	1254432.SCE1572_22460	1.112e-133	444.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2YU99@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158518_k127_3910748_0	1382356.JQMP01000004_gene597	8.309e-147	499.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi,27XS3@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158518_k127_3910748_2	525904.Tter_0192	1.8e-98	351.0	COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria	2|Bacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158518_k127_3920648_1	383372.Rcas_4113	4.059e-112	377.0	COG0247@1|root,COG0247@2|Bacteria,2G7VD@200795|Chloroflexi,3754W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
SRR25158518_k127_3920648_2	765420.OSCT_2315	3.75e-62	231.0	COG3075@1|root,COG3075@2|Bacteria,2G877@200795|Chloroflexi,374VB@32061|Chloroflexia	32061|Chloroflexia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
SRR25158518_k127_3920648_0	383372.Rcas_4111	7.891e-151	495.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi,3750F@32061|Chloroflexia	32061|Chloroflexia	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
SRR25158518_k127_3922565_3	1123072.AUDH01000003_gene1038	0.0001911	49.0	COG2963@1|root,COG2963@2|Bacteria,1RKI9@1224|Proteobacteria,2UDYB@28211|Alphaproteobacteria,2JURI@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158518_k127_3922565_1	1007103.AFHW01000023_gene266	8.807e-26	115.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,4HIJB@91061|Bacilli,26Y6Q@186822|Paenibacillaceae	91061|Bacilli	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
SRR25158518_k127_3922565_0	1210884.HG799462_gene9225	1.036e-104	359.0	COG3316@1|root,COG3316@2|Bacteria,2J4XX@203682|Planctomycetes	203682|Planctomycetes	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
SRR25158518_k127_3922565_2	575540.Isop_2341	2.12e-09	67.0	COG1595@1|root,COG1595@2|Bacteria,2IZPG@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_3924036_0	525904.Tter_1733	3.843e-34	144.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SRR25158518_k127_3924036_1	525904.Tter_1915	2.418e-33	149.0	28NWQ@1|root,2ZBUI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3924036_2	1211815.CBYP010000006_gene276	6.667e-06	58.0	2EN76@1|root,33FV1@2|Bacteria,2GYKJ@201174|Actinobacteria,4ETHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_3924060_1	266117.Rxyl_0972	7.407e-47	183.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4CQD0@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_3924060_0	391735.Veis_2041	3.008e-61	223.0	COG2390@1|root,COG2390@2|Bacteria,1MX3F@1224|Proteobacteria,2VP7U@28216|Betaproteobacteria,4AG9Q@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,Sugar-bind
SRR25158518_k127_3936564_5	395963.Bind_0007	1.525e-23	102.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,3N9KF@45404|Beijerinckiaceae	28211|Alphaproteobacteria	H	Porphobilinogen deaminase, dipyromethane cofactor binding domain	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SRR25158518_k127_3936564_4	867903.ThesuDRAFT_01613	1.996e-30	139.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158518_k127_3936564_6	316274.Haur_3543	1.118e-19	100.0	COG0789@1|root,COG0789@2|Bacteria,2GBIN@200795|Chloroflexi,375XH@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158518_k127_3936564_8	309798.COPRO5265_1141	0.000607	47.0	COG1918@1|root,COG1918@2|Bacteria,1VK8Z@1239|Firmicutes	1239|Firmicutes	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SRR25158518_k127_3936564_1	368407.Memar_1784	2.337e-84	312.0	COG0370@1|root,arCOG00359@2157|Archaea,2XU46@28890|Euryarchaeota,2N913@224756|Methanomicrobia	224756|Methanomicrobia	P	Ferrous iron transport B domain protein	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SRR25158518_k127_3936564_2	585531.HMPREF0063_10544	1.733e-73	274.0	COG3253@1|root,COG3253@2|Bacteria,2GK24@201174|Actinobacteria,4DP69@85009|Propionibacteriales	201174|Actinobacteria	S	Chlorite dismutase	cld	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158518_k127_3936564_0	1158050.KB895452_gene297	4.614e-133	443.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,1W7W4@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158518_k127_3936564_3	28444.JODQ01000001_gene2784	2.697e-37	157.0	COG2222@1|root,COG2222@2|Bacteria,2IBP7@201174|Actinobacteria,4EIEZ@85012|Streptosporangiales	201174|Actinobacteria	M	sugar isomerase	-	-	-	-	-	-	-	-	-	-	-	-	SIS
SRR25158518_k127_3936564_7	1380394.JADL01000005_gene5440	9.216e-08	58.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2JREK@204441|Rhodospirillales	204441|Rhodospirillales	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158518_k127_3953646_2	926560.KE387027_gene1038	2.204e-77	266.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158518_k127_3953646_6	323259.Mhun_2801	5.364e-07	61.0	COG2968@1|root,arCOG04715@2157|Archaea,2XZAZ@28890|Euryarchaeota,2N9TF@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158518_k127_3953646_1	1128421.JAGA01000002_gene1247	2.755e-87	320.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158518_k127_3953646_4	1411123.JQNH01000001_gene1883	4.07e-21	106.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TQSH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_3953646_5	1173026.Glo7428_4961	7.841e-09	66.0	COG5654@1|root,COG5654@2|Bacteria,1GBKD@1117|Cyanobacteria	1117|Cyanobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SRR25158518_k127_3953646_0	1068978.AMETH_6072	1.269e-198	648.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4DX7G@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158518_k127_3953646_3	1504319.GM45_0705	1.072e-38	156.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,3UWMS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158518_k127_3975656_2	285535.JOEY01000013_gene4671	1.893e-08	64.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria	201174|Actinobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_3975656_0	1000565.METUNv1_02855	1.154e-26	121.0	COG4359@1|root,COG4359@2|Bacteria,1REUD@1224|Proteobacteria,2VJXZ@28216|Betaproteobacteria,2KYNT@206389|Rhodocyclales	206389|Rhodocyclales	E	Putative Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158518_k127_3975656_1	1150599.MPHLEI_24329	1.554e-14	81.0	COG1595@1|root,COG1595@2|Bacteria,2GRZW@201174|Actinobacteria,23459@1762|Mycobacteriaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158518_k127_3996980_5	375286.mma_0404	0.0009201	45.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2VNGN@28216|Betaproteobacteria,472KC@75682|Oxalobacteraceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158518_k127_3996980_1	33876.JNXY01000029_gene2661	2.17e-117	405.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158518_k127_3996980_0	33876.JNXY01000029_gene2662	3.969e-127	415.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4D8QU@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_3996980_3	33876.JNXY01000029_gene2663	6.04e-47	177.0	COG1309@1|root,COG1309@2|Bacteria,2HWQ4@201174|Actinobacteria,4DJWP@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158518_k127_3996980_2	1133850.SHJG_5346	4.144e-49	192.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158518_k127_3996980_4	1122939.ATUD01000002_gene1481	3.857e-30	124.0	COG0524@1|root,COG0524@2|Bacteria,2GYHF@201174|Actinobacteria,4CQ63@84995|Rubrobacteria	84995|Rubrobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158518_k127_3998907_3	935948.KE386494_gene69	5.083e-74	252.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,42F99@68295|Thermoanaerobacterales	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158518_k127_3998907_5	765420.OSCT_1050	6.208e-17	89.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,375N3@32061|Chloroflexia	32061|Chloroflexia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158518_k127_3998907_0	635013.TherJR_1279	1.481e-172	558.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25ZZN@186807|Peptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158518_k127_3998907_2	1121430.JMLG01000001_gene2103	4.9e-83	284.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
SRR25158518_k127_3998907_4	479434.Sthe_0705	1.093e-45	183.0	COG0613@1|root,COG0613@2|Bacteria,2G6H4@200795|Chloroflexi,27YVQ@189775|Thermomicrobia	189775|Thermomicrobia	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRR25158518_k127_3998907_1	365046.Rta_28730	2.165e-89	304.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,4AC5T@80864|Comamonadaceae	28216|Betaproteobacteria	P	Membrane protein TerC	terC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,TerC
SRR25158518_k127_4004300_4	1174528.JH992898_gene1697	3.66e-15	87.0	COG0204@1|root,COG0204@2|Bacteria,1G1AK@1117|Cyanobacteria,1JJSU@1189|Stigonemataceae	1117|Cyanobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158518_k127_4004300_2	1380356.JNIK01000014_gene3482	2.402e-72	269.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158518_k127_4004300_0	1122939.ATUD01000009_gene3118	2.595e-156	506.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CRTD@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
SRR25158518_k127_4004300_1	880073.Calab_1764	5.795e-112	383.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158518_k127_4004300_3	479431.Namu_4420	5.181e-24	106.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4ERRS@85013|Frankiales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158518_k127_4011126_6	223926.28805940	0.0004651	54.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG2199@2|Bacteria,1NS3W@1224|Proteobacteria,1SKY3@1236|Gammaproteobacteria,1XSPX@135623|Vibrionales	135623|Vibrionales	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	2.7.7.65	ko:K20957	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,SBP_bac_3
SRR25158518_k127_4011126_0	1429046.RR21198_2582	3.379e-108	364.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria,4FUIQ@85025|Nocardiaceae	201174|Actinobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158518_k127_4011126_5	292459.STH2963	1.75e-28	122.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia	186801|Clostridia	K	domain protein	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
SRR25158518_k127_4011126_1	1192034.CAP_6745	2.717e-85	290.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	-	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
SRR25158518_k127_4011126_4	1382356.JQMP01000003_gene1375	1.764e-36	148.0	COG1028@1|root,COG1028@2|Bacteria,2G8JD@200795|Chloroflexi,27YCF@189775|Thermomicrobia	189775|Thermomicrobia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158518_k127_4011126_3	1134445.AJJM01000006_gene3316	4.075e-51	198.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158518_k127_4011126_2	118163.Ple7327_4280	2.464e-52	192.0	COG0520@1|root,COG0520@2|Bacteria,1G0VG@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158518_k127_4022579_7	28444.JODQ01000007_gene5411	1.412e-81	297.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158518_k127_4022579_4	926569.ANT_08060	2.771e-88	303.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
SRR25158518_k127_4022579_0	309801.trd_1468	1.212e-191	610.0	COG1012@1|root,COG1012@2|Bacteria,2G5NY@200795|Chloroflexi,27XK3@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158518_k127_4022579_14	1266909.AUAG01000035_gene1154	1.209e-08	64.0	COG1848@1|root,COG1848@2|Bacteria,1NH4K@1224|Proteobacteria,1SINK@1236|Gammaproteobacteria,1X22T@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158518_k127_4022579_13	479434.Sthe_3271	2.39e-09	62.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SRR25158518_k127_4022579_5	42256.RradSPS_2073	1.009e-87	317.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CQA4@84995|Rubrobacteria	84995|Rubrobacteria	C	COG COG1454 Alcohol dehydrogenase class IV Energy production and conversion	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
SRR25158518_k127_4022579_6	443255.SCLAV_p0994	1.313e-84	302.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	mmsB2	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158518_k127_4022579_1	1238182.C882_1124	2.515e-179	582.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JPZI@204441|Rhodospirillales	204441|Rhodospirillales	C	belongs to the aldehyde dehydrogenase family	puuC	-	1.2.1.54,1.2.1.99	ko:K09472,ko:K12254	ko00330,ko01100,map00330,map01100	M00136	R02549,R03177,R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158518_k127_4022579_3	290340.AAur_0649	3.763e-149	480.0	COG4948@1|root,COG4948@2|Bacteria,2IBIE@201174|Actinobacteria	201174|Actinobacteria	M	Mandelate racemase muconate lactonizing enzyme	-	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158518_k127_4022579_8	443255.SCLAV_p0997	4.278e-58	206.0	COG1795@1|root,COG1795@2|Bacteria,2IGCK@201174|Actinobacteria	201174|Actinobacteria	S	Formaldehyde-activating enzyme (Fae)	-	-	4.2.1.147	ko:K10713	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R08058	RC01583,RC01795	ko00000,ko00001,ko01000	-	-	-	Fae
SRR25158518_k127_4022579_2	1122247.C731_3065	1.749e-155	517.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,236SN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
SRR25158518_k127_4022579_11	1313172.YM304_27110	2.855e-34	136.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	MA20_15755	-	-	-	-	-	-	-	-	-	-	-	DUF4332
SRR25158518_k127_4022579_12	1048339.KB913029_gene3268	3.807e-20	105.0	COG1404@1|root,COG3420@1|root,COG1404@2|Bacteria,COG3420@2|Bacteria,2GJYH@201174|Actinobacteria,4ERYW@85013|Frankiales	201174|Actinobacteria	O	peptidase S8	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Inhibitor_I9,PD40,Peptidase_S8,fn3
SRR25158518_k127_4022579_9	1382306.JNIM01000001_gene720	6.294e-55	205.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
SRR25158518_k127_4022579_10	1120949.KB903294_gene4279	3.481e-50	195.0	COG0500@1|root,COG2226@2|Bacteria,2HUA5@201174|Actinobacteria,4DDGA@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158518_k127_4022579_15	1329516.JPST01000021_gene2536	1.612e-05	52.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,27B0P@186824|Thermoactinomycetaceae	91061|Bacilli	E	LeuA allosteric (dimerisation) domain	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158518_k127_403131_1	331869.BAL199_15868	1.622e-89	318.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,4BR94@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158518_k127_403131_2	1449351.RISW2_12815	7.136e-82	281.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TSYF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158518_k127_403131_6	1445613.JALM01000020_gene4722	7.501e-48	184.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E3AX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_403131_0	1121106.JQKB01000022_gene3702	3.373e-135	442.0	COG0402@1|root,COG0402@2|Bacteria,1MVMR@1224|Proteobacteria,2U0AM@28211|Alphaproteobacteria,2JRJS@204441|Rhodospirillales	204441|Rhodospirillales	F	Amidohydrolase family	-	-	3.5.2.18	ko:K15358	ko00760,ko01120,map00760,map01120	-	R07984	RC01933	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158518_k127_403131_4	1297569.MESS2_50044	2.05e-58	208.0	28I63@1|root,2Z897@2|Bacteria,1N3VY@1224|Proteobacteria,2TTW0@28211|Alphaproteobacteria,43MWI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Amino acid synthesis	MA20_26545	-	-	-	-	-	-	-	-	-	-	-	AA_synth
SRR25158518_k127_403131_3	1043493.BBLU01000006_gene2132	1.92e-62	221.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158518_k127_403131_9	1463885.KL578572_gene9692	9.916e-14	85.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
SRR25158518_k127_403131_8	861299.J421_2432	7.92e-24	108.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_403131_5	1463881.KL591003_gene5650	3.102e-50	186.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158518_k127_403131_7	1304865.JAGF01000001_gene1006	4.101e-31	133.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158518_k127_403131_10	1304874.JAFY01000007_gene1896	4.866e-12	66.0	COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes	508458|Synergistetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158518_k127_403499_0	3988.XP_002535660.1	8.722e-31	124.0	COG0384@1|root,KOG3033@2759|Eukaryota	2759|Eukaryota	K	negative regulation of SMAD protein signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
SRR25158518_k127_403499_1	979556.MTES_0183	7.701e-14	83.0	COG1073@1|root,COG1073@2|Bacteria,2IASH@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158518_k127_4068724_1	1380390.JIAT01000009_gene1628	8.157e-113	402.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158518_k127_4068724_0	1313172.YM304_27180	1.222e-151	486.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CNI9@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158518_k127_4075686_4	926559.JoomaDRAFT_0008	2.373e-37	154.0	COG0863@1|root,COG0863@2|Bacteria,4NTFS@976|Bacteroidetes,1I50P@117743|Flavobacteriia	976|Bacteroidetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SRR25158518_k127_4075686_0	1169154.KB897776_gene1992	8.248e-68	257.0	COG1512@1|root,COG1512@2|Bacteria,2GMGW@201174|Actinobacteria	201174|Actinobacteria	M	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
SRR25158518_k127_4075686_1	1416759.AYMR01000009_gene2774	3.201e-67	253.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria,4FMNN@85023|Microbacteriaceae	201174|Actinobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158518_k127_4075686_3	1380390.JIAT01000009_gene1899	1.992e-52	199.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4CPVH@84995|Rubrobacteria	84995|Rubrobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158518_k127_4075686_5	311424.DhcVS_307	4.619e-08	60.0	2A4G3@1|root,30T26@2|Bacteria,2GAY4@200795|Chloroflexi,34DJS@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4075686_2	1242864.D187_000069	4.871e-64	229.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YZXT@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158518_k127_4076100_2	1298863.AUEP01000005_gene2400	2.72e-86	302.0	COG0769@1|root,COG0769@2|Bacteria,2GME3@201174|Actinobacteria,4DPYG@85009|Propionibacteriales	201174|Actinobacteria	M	Mur ligase middle domain	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,TPR_5
SRR25158518_k127_4076100_6	1028800.RG540_CH25740	5.947e-25	109.0	2EBN3@1|root,335NA@2|Bacteria,1PS1W@1224|Proteobacteria,2V490@28211|Alphaproteobacteria,4BFSU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158518_k127_4076100_1	397278.JOJN01000004_gene1403	0.0	1141.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,4DP39@85009|Propionibacteriales	201174|Actinobacteria	HJM	RimK-like ATP-grasp domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158518_k127_4076100_3	1032480.MLP_14770	3.445e-82	281.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,4DP1Z@85009|Propionibacteriales	201174|Actinobacteria	PQ	Peptidase family S51	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158518_k127_4076100_8	1206730.BAGA01000111_gene5442	0.0005525	51.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4FX2G@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SRR25158518_k127_4076100_5	552811.Dehly_1213	2.658e-39	163.0	COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4076100_7	265072.Mfla_1015	3.05e-11	73.0	2DQZQ@1|root,339JR@2|Bacteria,1NNI2@1224|Proteobacteria,2W5R6@28216|Betaproteobacteria,2KN9M@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4076100_4	290397.Adeh_2091	7.478e-66	237.0	COG0266@1|root,COG0266@2|Bacteria,1N1J5@1224|Proteobacteria,433TA@68525|delta/epsilon subdivisions,2X3D6@28221|Deltaproteobacteria,2YVHV@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158518_k127_4076100_0	1313172.YM304_09490	0.0	1491.0	COG1201@1|root,COG1201@2|Bacteria,2I6VR@201174|Actinobacteria,4CNBF@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DEAD-like helicases superfamily	-	-	-	ko:K03724,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR25158518_k127_4081254_9	936455.KI421499_gene6669	1.465e-09	64.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JQNW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	MA20_24480	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158518_k127_4081254_4	1134445.AJJM01000032_gene1387	2.069e-30	128.0	2E3HM@1|root,32YG7@2|Bacteria,2IQSQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4081254_5	246197.MXAN_2361	1.508e-23	115.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,42TB9@68525|delta/epsilon subdivisions,2WXEF@28221|Deltaproteobacteria,2YW3Y@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158518_k127_4081254_7	266117.Rxyl_2877	2.686e-18	99.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
SRR25158518_k127_4081254_1	1463853.JOHW01000010_gene1317	2.724e-100	334.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158518_k127_4081254_8	479432.Sros_4967	1.286e-15	84.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria,4EK7S@85012|Streptosporangiales	201174|Actinobacteria	K	transcriptional regulator, ArsR family	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
SRR25158518_k127_4081254_2	392500.Swoo_0647	4.175e-43	181.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,2Q9PE@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
SRR25158518_k127_4081254_6	1157637.KB892090_gene6354	4.099e-21	109.0	COG4733@1|root,COG5479@1|root,COG4733@2|Bacteria,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,SpoIID,VCBS
SRR25158518_k127_4081254_3	1385519.N801_05270	1.127e-32	145.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158518_k127_4081254_0	266117.Rxyl_2544	0.0	1084.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,2GKN1@201174|Actinobacteria,4CRR1@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-binding	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
SRR25158518_k127_4082720_0	926560.KE387027_gene419	7.084e-160	520.0	COG0477@1|root,COG0477@2|Bacteria,1WMC1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_4082720_2	1121946.AUAX01000019_gene7777	1.849e-29	126.0	COG3340@1|root,COG3340@2|Bacteria,2ISWE@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158518_k127_4082720_1	552811.Dehly_0405	1.574e-30	126.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,34DCQ@301297|Dehalococcoidia	200795|Chloroflexi	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
SRR25158518_k127_4082720_3	269799.Gmet_1223	1.492e-28	129.0	COG0420@1|root,COG0420@2|Bacteria,1MXMJ@1224|Proteobacteria,42Q5U@68525|delta/epsilon subdivisions,2WINF@28221|Deltaproteobacteria,43SKW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Calcineurin-like phosphoesterase	sbcD-1	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
SRR25158518_k127_4082720_4	123899.JPQP01000018_gene84	0.0005155	53.0	COG0419@1|root,COG0419@2|Bacteria,1MXMI@1224|Proteobacteria,2VN4Y@28216|Betaproteobacteria,3T367@506|Alcaligenaceae	28216|Betaproteobacteria	L	RecF RecN SMC N terminal domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
SRR25158518_k127_4085096_3	1041930.Mtc_0877	2.462e-75	265.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2N97R@224756|Methanomicrobia	224756|Methanomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158518_k127_4085096_2	1303518.CCALI_00982	5.191e-83	308.0	COG1253@1|root,COG1253@2|Bacteria	2|Bacteria	E	flavin adenine dinucleotide binding	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158518_k127_4085096_0	2074.JNYD01000015_gene4418	9.998e-108	366.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DZZ7@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158518_k127_4085096_6	1274374.CBLK010000059_gene335	1.398e-35	153.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,26YJV@186822|Paenibacillaceae	91061|Bacilli	J	endoribonuclease L-PSP	yhaR	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158518_k127_4085096_7	69042.WH5701_13490	4.082e-33	147.0	COG1947@1|root,COG1947@2|Bacteria,1G0YY@1117|Cyanobacteria,1GZVI@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158518_k127_4085096_4	1382356.JQMP01000003_gene1346	1.326e-51	206.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi,27XUP@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158518_k127_4085096_1	479434.Sthe_0915	1.023e-98	343.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,27XRB@189775|Thermomicrobia	189775|Thermomicrobia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158518_k127_4085096_5	383372.Rcas_4079	1.214e-39	156.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi,375M6@32061|Chloroflexia	32061|Chloroflexia	K	TIGRFAM ribosomal-protein-alanine acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158518_k127_4110564_0	593907.Celgi_2417	2.312e-146	472.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4F0UZ@85016|Cellulomonadaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158518_k127_4110564_2	195250.CM001776_gene2695	1.387e-61	225.0	28NY3@1|root,2ZBVC@2|Bacteria,1G5MR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4110564_4	765420.OSCT_1250	9.916e-10	68.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi,375QN@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
SRR25158518_k127_4110564_3	1382359.JIAL01000001_gene1961	3.767e-22	109.0	COG0668@1|root,COG0668@2|Bacteria,3Y4K3@57723|Acidobacteria,2JJAD@204432|Acidobacteriia	204432|Acidobacteriia	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158518_k127_4110564_1	1191523.MROS_0721	1.377e-127	416.0	COG1932@1|root,COG1932@2|Bacteria	2|Bacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158518_k127_4125702_3	32057.KB217478_gene1151	6.217e-42	168.0	COG3408@1|root,COG3408@2|Bacteria,1G3RM@1117|Cyanobacteria,1HM48@1161|Nostocales	1117|Cyanobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SRR25158518_k127_4125702_2	1430331.EP10_03210	3.403e-63	228.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBYE@91061|Bacilli,1WG2D@129337|Geobacillus	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158518_k127_4125702_1	748449.Halha_1835	3.016e-68	244.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,3WBMZ@53433|Halanaerobiales	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
SRR25158518_k127_4125702_0	1007103.AFHW01000047_gene2861	3.171e-76	272.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,4HBRS@91061|Bacilli,26RI1@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158518_k127_4125702_4	55952.BU52_07540	1.108e-41	163.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_413768_2	1382356.JQMP01000001_gene828	4.359e-21	94.0	COG0113@1|root,COG0113@2|Bacteria,2G5QT@200795|Chloroflexi,27XTX@189775|Thermomicrobia	189775|Thermomicrobia	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158518_k127_413768_0	1254432.SCE1572_51770	1.017e-141	466.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria,2YU3Q@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158518_k127_413768_1	1288083.AUKR01000008_gene1727	4.764e-113	383.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158518_k127_413768_3	1382304.JNIL01000001_gene1030	8.87e-11	75.0	COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli	91061|Bacilli	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158518_k127_4139022_1	311424.DhcVS_1192	6.047e-40	161.0	COG0484@1|root,COG0484@2|Bacteria,2G657@200795|Chloroflexi,34CZG@301297|Dehalococcoidia	301297|Dehalococcoidia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SRR25158518_k127_4139022_0	479434.Sthe_0441	0.0	1080.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158518_k127_4139022_2	1336233.JAEH01000031_gene239	2.21e-06	59.0	arCOG13953@1|root,2ZC7Q@2|Bacteria,1NUV6@1224|Proteobacteria,1SNIB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4143445_2	871968.DESME_15100	2.962e-63	235.0	COG1629@1|root,COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,COG4771@2|Bacteria,1V0RA@1239|Firmicutes,24AV7@186801|Clostridia,260Q2@186807|Peptococcaceae	186801|Clostridia	EM	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Lipase_GDSL_2,TIG
SRR25158518_k127_4143445_11	1386089.N865_05350	1.421e-10	74.0	COG4733@1|root,COG4733@2|Bacteria,2I7XV@201174|Actinobacteria,4FK2V@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SRR25158518_k127_4143445_10	1341155.FSS13T_13600	8.82e-12	72.0	2AFKC@1|root,315MA@2|Bacteria,4PJSY@976|Bacteroidetes,1IAAY@117743|Flavobacteriia,2NZ4P@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF3788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
SRR25158518_k127_4143445_12	2074.JNYD01000013_gene6813	5.768e-06	58.0	COG5343@1|root,COG5343@2|Bacteria,2HM9H@201174|Actinobacteria,4E3TB@85010|Pseudonocardiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158518_k127_4143445_3	1382356.JQMP01000003_gene1500	1.163e-44	169.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27Z8H@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_4143445_8	235985.BBPN01000014_gene5458	4.351e-27	119.0	2BFUD@1|root,329PJ@2|Bacteria,2IMNG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4143445_0	1173028.ANKO01000080_gene4666	9.052e-207	663.0	COG0514@1|root,COG1040@1|root,COG0514@2|Bacteria,COG1040@2|Bacteria,1G3B9@1117|Cyanobacteria,1H7H0@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
SRR25158518_k127_4143445_7	479435.Kfla_1126	2.482e-27	124.0	2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4143445_5	485913.Krac_8487	7.745e-42	173.0	COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
SRR25158518_k127_4143445_1	1121272.KB903250_gene2742	9.413e-107	360.0	COG2309@1|root,COG2309@2|Bacteria,2ID23@201174|Actinobacteria,4DHD7@85008|Micromonosporales	201174|Actinobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
SRR25158518_k127_4143445_4	530564.Psta_4322	7.681e-42	166.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
SRR25158518_k127_4143445_9	525909.Afer_0716	1.967e-23	101.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4CNF8@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158518_k127_4151374_0	644966.Tmar_0951	8.695e-131	427.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158518_k127_4151374_2	1382356.JQMP01000003_gene2333	5.104e-21	102.0	COG0511@1|root,COG0511@2|Bacteria,2G94M@200795|Chloroflexi,27YJ8@189775|Thermomicrobia	189775|Thermomicrobia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158518_k127_4151374_1	1121472.AQWN01000002_gene2330	1.538e-101	342.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,260BR@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158518_k127_4152147_0	1297569.MESS2_960006	4.423e-97	325.0	COG0601@1|root,COG0601@2|Bacteria,1R6RG@1224|Proteobacteria,2U10E@28211|Alphaproteobacteria,43R3C@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158518_k127_4152147_2	1297570.MESS4_20066	3.503e-88	302.0	COG1173@1|root,COG1173@2|Bacteria,1NRWG@1224|Proteobacteria,2UPAF@28211|Alphaproteobacteria,43PKS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158518_k127_4152147_1	1297570.MESS4_20065	2.589e-96	344.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,43QYI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158518_k127_4152147_3	1297570.MESS4_20064	7.107e-69	259.0	COG4608@1|root,COG4608@2|Bacteria,1NU61@1224|Proteobacteria,2UR5X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158518_k127_4154953_2	1487921.DP68_09700	1.321e-78	277.0	COG3288@1|root,COG3288@2|Bacteria,1UP6K@1239|Firmicutes,25H78@186801|Clostridia,36GD7@31979|Clostridiaceae	186801|Clostridia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158518_k127_4154953_9	882083.SacmaDRAFT_2314	1.272e-21	109.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria,4E6B1@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158518_k127_4154953_8	631362.Thi970DRAFT_00339	4.076e-22	113.0	COG0789@1|root,COG0789@2|Bacteria,1NGZ7@1224|Proteobacteria,1TK9V@1236|Gammaproteobacteria,1X0W7@135613|Chromatiales	135613|Chromatiales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158518_k127_4154953_1	631362.Thi970DRAFT_00459	3.36e-81	288.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SRR25158518_k127_4154953_0	926550.CLDAP_26270	2.056e-127	418.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158518_k127_4154953_4	278957.ABEA03000166_gene4019	1.601e-59	213.0	COG5012@1|root,COG5012@2|Bacteria,46V56@74201|Verrucomicrobia,3K7ZT@414999|Opitutae	414999|Opitutae	S	Methionine synthase B12-binding module cap domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158518_k127_4154953_3	357808.RoseRS_0359	2.33e-75	276.0	COG0451@1|root,COG0451@2|Bacteria,2G87T@200795|Chloroflexi	200795|Chloroflexi	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158518_k127_4154953_5	485913.Krac_5801	4.91e-47	178.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158518_k127_4154953_11	397278.JOJN01000002_gene187	4.198e-11	72.0	COG3427@1|root,COG3427@2|Bacteria,2IEYK@201174|Actinobacteria,4DQIP@85009|Propionibacteriales	201174|Actinobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158518_k127_4154953_7	1128421.JAGA01000001_gene2230	8.965e-36	152.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K03520,ko:K07302	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
SRR25158518_k127_4154953_6	1089551.KE386572_gene3486	9.29e-45	168.0	COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,2TS73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	MA20_13960	-	1.2.5.3,1.3.7.9	ko:K03518,ko:K04107	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316,R11168	RC00490,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
SRR25158518_k127_4154953_10	1040983.AXAE01000005_gene1520	7.752e-21	101.0	COG1529@1|root,COG1529@2|Bacteria,1NNFR@1224|Proteobacteria,2TVHX@28211|Alphaproteobacteria,43R41@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	MA20_13965	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158518_k127_4161342_1	926560.KE387023_gene2911	6.506e-09	64.0	2DNJQ@1|root,32XUQ@2|Bacteria,1WJZQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158518_k127_4161342_0	288000.BBta_7802	4.997e-45	177.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,3JVXA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158518_k127_418521_1	243231.GSU0122	2.274e-130	433.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hyaL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SRR25158518_k127_418521_6	383372.Rcas_3146	2.075e-44	176.0	COG1969@1|root,COG1969@2|Bacteria,2GAHC@200795|Chloroflexi,37655@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
SRR25158518_k127_418521_8	1449976.KALB_4194	3.238e-20	106.0	COG0680@1|root,COG0680@2|Bacteria,2GSEX@201174|Actinobacteria	201174|Actinobacteria	C	hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SRR25158518_k127_418521_9	694427.Palpr_0869	5.466e-06	58.0	COG0484@1|root,COG0484@2|Bacteria,4P0AH@976|Bacteroidetes,2FYI2@200643|Bacteroidia	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_418521_0	525904.Tter_0669	8.26e-145	488.0	COG1404@1|root,COG1404@2|Bacteria,2NQYY@2323|unclassified Bacteria	2|Bacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Inhibitor_I9,PA,Peptidase_S8
SRR25158518_k127_418521_7	479434.Sthe_1633	1.352e-38	151.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
SRR25158518_k127_418521_4	1313172.YM304_17800	5.049e-47	181.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158518_k127_418521_3	1194165.CAJF01000013_gene1263	2.287e-51	188.0	COG1309@1|root,COG1309@2|Bacteria,2IR68@201174|Actinobacteria,4FSCQ@85023|Microbacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158518_k127_418521_2	37919.EP51_13930	5.809e-74	263.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4FY2A@85025|Nocardiaceae	201174|Actinobacteria	CG	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SRR25158518_k127_418521_5	926561.KB900617_gene1375	2.368e-45	178.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WA5Y@53433|Halanaerobiales	186801|Clostridia	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158518_k127_4195768_5	1463841.JOIR01000012_gene2152	2.993e-15	81.0	COG0477@1|root,COG2814@2|Bacteria,2I96S@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158518_k127_4195768_1	479434.Sthe_0838	1.384e-79	291.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi,27XGA@189775|Thermomicrobia	189775|Thermomicrobia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158518_k127_4195768_4	864069.MicloDRAFT_00044110	4.263e-20	100.0	COG4803@1|root,COG4803@2|Bacteria,1RC5W@1224|Proteobacteria,2U8DH@28211|Alphaproteobacteria,1JR3N@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158518_k127_4195768_8	356851.JOAN01000003_gene1544	0.0002077	55.0	2EQCM@1|root,345QA@2|Bacteria,2IPGD@201174|Actinobacteria,4DEG6@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4195768_3	1150399.AQYK01000002_gene2670	8.145e-43	166.0	COG4106@1|root,COG4106@2|Bacteria,2ISFP@201174|Actinobacteria,4FPCY@85023|Microbacteriaceae	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158518_k127_4195768_0	1521187.JPIM01000120_gene293	1.613e-100	344.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi,376BM@32061|Chloroflexia	32061|Chloroflexia	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158518_k127_4195768_2	290397.Adeh_0419	1.03e-78	293.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158518_k127_4195768_6	313589.JNB_15018	1.217e-09	70.0	COG0746@1|root,COG0746@2|Bacteria,2HXM8@201174|Actinobacteria,4FHCJ@85021|Intrasporangiaceae	201174|Actinobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SRR25158518_k127_4195768_7	1101190.ARWB01000001_gene3700	7.399e-08	59.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,2UDE1@28211|Alphaproteobacteria,370F3@31993|Methylocystaceae	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158518_k127_4198729_0	525904.Tter_0881	5.501e-299	929.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158518_k127_4198729_1	552811.Dehly_1536	7.044e-62	220.0	COG0668@1|root,COG0668@2|Bacteria,2G75W@200795|Chloroflexi,34D81@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
SRR25158518_k127_4205756_0	322710.Avin_43850	1.315e-90	312.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158518_k127_4205756_1	1122223.KB890696_gene247	2.771e-46	178.0	COG0813@1|root,COG0813@2|Bacteria,1WIF6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	TIGRFAM purine-nucleoside phosphorylase, family 1 (deoD)	-	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SRR25158518_k127_4205756_2	1535287.JP74_05575	3.117e-11	66.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U8NT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158518_k127_421610_2	1126627.BAWE01000005_gene5693	6.351e-34	135.0	COG0663@1|root,COG0663@2|Bacteria,1QWDP@1224|Proteobacteria,2TWVZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158518_k127_421610_0	1232410.KI421416_gene2577	4.113e-130	432.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,43T06@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
SRR25158518_k127_421610_1	1232410.KI421416_gene2578	6.208e-38	156.0	COG1082@1|root,COG1082@2|Bacteria,1NUZZ@1224|Proteobacteria,42WFH@68525|delta/epsilon subdivisions,2WV2N@28221|Deltaproteobacteria,43UTG@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158518_k127_421610_3	883.DvMF_1894	8.38e-12	68.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2WJXH@28221|Deltaproteobacteria,2M7VU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM N-acetylneuraminic acid synthase	-	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
SRR25158518_k127_4228009_2	1123288.SOV_3c01570	1.008e-18	87.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4H4EU@909932|Negativicutes	909932|Negativicutes	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158518_k127_4228009_1	1122239.AULS01000009_gene1550	1.6e-61	239.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4FMDT@85023|Microbacteriaceae	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,cNMP_binding
SRR25158518_k127_4228009_0	383372.Rcas_0234	2.479e-151	488.0	COG3938@1|root,COG3938@2|Bacteria,2G5PY@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the proline racemase family	-	-	5.1.1.4,5.1.1.8	ko:K01777,ko:K12658	ko00330,ko01100,map00330,map01100	-	R01255,R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
SRR25158518_k127_4229320_1	926692.AZYG01000010_gene1144	1.103e-67	244.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,3WAE2@53433|Halanaerobiales	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158518_k127_4229320_0	867903.ThesuDRAFT_01781	4.471e-162	522.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WCFT@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158518_k127_4229320_2	1122143.AUEG01000002_gene760	4.533e-35	145.0	COG0726@1|root,COG1388@1|root,COG0726@2|Bacteria,COG1388@2|Bacteria,1UZ7Q@1239|Firmicutes,4IPRX@91061|Bacilli,27FRM@186828|Carnobacteriaceae	91061|Bacilli	GM	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
SRR25158518_k127_4229394_4	66373.JOFQ01000018_gene1151	1.114e-35	149.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158518_k127_4229394_5	1089455.MOPEL_074_00890	6.419e-29	133.0	COG3850@1|root,COG3850@2|Bacteria,2HFHQ@201174|Actinobacteria,4F72S@85018|Dermatophilaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158518_k127_4229394_2	768671.ThimaDRAFT_0877	9.811e-72	251.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WY32@135613|Chromatiales	135613|Chromatiales	P	SMART Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158518_k127_4229394_6	398512.JQKC01000023_gene3271	1.448e-13	85.0	COG1361@1|root,COG2333@1|root,COG2866@1|root,COG2931@1|root,COG3210@1|root,COG3266@1|root,COG3291@1|root,COG3391@1|root,COG4733@1|root,COG5492@1|root,COG1361@2|Bacteria,COG2333@2|Bacteria,COG2866@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,1TQ2T@1239|Firmicutes,24EP0@186801|Clostridia,3WI1H@541000|Ruminococcaceae	186801|Clostridia	MU	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PKD,Paired_CXXCH_1,SLH,fn3
SRR25158518_k127_4229394_3	367299.JOEE01000001_gene1553	4.109e-41	174.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_5,DUF11,SdrD_B
SRR25158518_k127_4229394_0	626939.HMPREF9443_01876	1.15e-117	403.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4H25A@909932|Negativicutes	909932|Negativicutes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158518_k127_4229394_1	1128421.JAGA01000003_gene3530	8.53e-99	345.0	COG0358@1|root,COG0358@2|Bacteria,2NNNJ@2323|unclassified Bacteria	2|Bacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158518_k127_4235845_0	1382356.JQMP01000004_gene475	3.899e-101	339.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158518_k127_4235845_3	525904.Tter_1614	1.992e-78	286.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
SRR25158518_k127_4235845_1	326427.Cagg_2847	7.722e-93	334.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,374X6@32061|Chloroflexia	32061|Chloroflexia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158518_k127_4235845_2	1382356.JQMP01000004_gene471	3.149e-80	296.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
SRR25158518_k127_4235845_4	243231.GSU3071	1.956e-26	126.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
SRR25158518_k127_4244655_1	1128421.JAGA01000003_gene3606	1.428e-81	284.0	COG0138@1|root,COG0138@2|Bacteria,2NNQ2@2323|unclassified Bacteria	2|Bacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158518_k127_4244655_0	1411123.JQNH01000001_gene1340	1.474e-130	436.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158518_k127_4244655_3	35754.JNYJ01000021_gene421	1.901e-08	64.0	291S1@1|root,2ZPBY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4244655_2	498761.HM1_0751	2.845e-23	102.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158518_k127_4263752_3	1382356.JQMP01000003_gene2595	4.92e-35	152.0	COG5282@1|root,COG5282@2|Bacteria,2G800@200795|Chloroflexi,27XTJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158518_k127_4263752_1	266117.Rxyl_1602	1.052e-61	226.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CQ0N@84995|Rubrobacteria	84995|Rubrobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158518_k127_4263752_2	1089553.Tph_c05490	5.717e-44	175.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,42FVJ@68295|Thermoanaerobacterales	186801|Clostridia	D	ATPase MipZ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
SRR25158518_k127_4263752_4	1382306.JNIM01000001_gene424	7.554e-27	119.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158518_k127_4263752_0	298655.KI912266_gene6560	1.154e-74	254.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4EUWY@85013|Frankiales	201174|Actinobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158518_k127_4271183_6	471853.Bcav_2267	1.382e-14	75.0	COG0673@1|root,COG0673@2|Bacteria,2IE7D@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158518_k127_4271183_2	1463825.JNXC01000002_gene4798	1.119e-46	178.0	COG1670@1|root,COG1670@2|Bacteria,2IIWF@201174|Actinobacteria,4E41X@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
SRR25158518_k127_4271183_0	1122915.AUGY01000013_gene2826	1.95e-134	451.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,4HBQW@91061|Bacilli,26RH8@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl hydrolase	ypdC	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
SRR25158518_k127_4271183_5	1122139.KB907877_gene3020	4.449e-36	149.0	COG1226@1|root,COG1226@2|Bacteria,1RBAK@1224|Proteobacteria,1S3S7@1236|Gammaproteobacteria,1XJFG@135619|Oceanospirillales	135619|Oceanospirillales	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
SRR25158518_k127_4271183_4	395019.Bmul_4571	1.227e-39	155.0	COG3554@1|root,COG3554@2|Bacteria,1N2WV@1224|Proteobacteria,2VXEY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
SRR25158518_k127_4271183_3	1123258.AQXZ01000014_gene5045	1.067e-44	178.0	COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4FWRS@85025|Nocardiaceae	201174|Actinobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
SRR25158518_k127_4271183_1	1381751.JAJB01000001_gene2879	5.847e-101	351.0	COG3214@1|root,COG3214@2|Bacteria,2HPNB@201174|Actinobacteria,4FB40@85019|Brevibacteriaceae	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158518_k127_4271183_9	1112204.GPOL_c07160	0.0009203	49.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4GDWT@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4271183_8	195103.CPF_1842	0.0001295	54.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,36EA1@31979|Clostridiaceae	186801|Clostridia	S	hmm pf06738	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
SRR25158518_k127_4271183_7	457425.XNR_3424	1.933e-10	72.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2GJMC@201174|Actinobacteria	201174|Actinobacteria	S	Amino acid export carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
SRR25158518_k127_427672_8	469383.Cwoe_2073	1.895e-13	81.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4CT5D@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158518_k127_427672_7	1121033.AUCF01000006_gene4119	1.42e-13	82.0	29YG2@1|root,30KAS@2|Bacteria,1Q4DK@1224|Proteobacteria,2VC04@28211|Alphaproteobacteria,2JXGQ@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_427672_0	1395571.TMS3_0110270	6.758e-185	609.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.99	ko:K09472	ko00330,ko01100,map00330,map01100	M00136	R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158518_k127_427672_3	1044.EH31_08425	1.38e-102	344.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,2K3AI@204457|Sphingomonadales	204457|Sphingomonadales	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158518_k127_427672_1	1044.EH31_08430	3.948e-141	466.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,2K5UF@204457|Sphingomonadales	204457|Sphingomonadales	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158518_k127_427672_2	765911.Thivi_3125	7.882e-122	403.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RPAZ@1236|Gammaproteobacteria,1WWIG@135613|Chromatiales	135613|Chromatiales	G	PFAM Ribulose bisphosphate carboxylase large	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large
SRR25158518_k127_427672_5	670487.Ocepr_2185	1.966e-28	127.0	COG2390@1|root,COG2390@2|Bacteria,1WMUX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sugar-bind
SRR25158518_k127_427672_4	330084.JNYZ01000008_gene6721	3.695e-51	202.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4E429@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM Class II Aldolase and Adducin N-terminal domain	fucA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158518_k127_4279043_0	1463934.JOCF01000085_gene618	5.007e-97	330.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158518_k127_4279043_2	1211815.CBYP010000007_gene320	1.188e-30	138.0	COG0251@1|root,COG0251@2|Bacteria,2IIB2@201174|Actinobacteria,4ETK2@85013|Frankiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158518_k127_4279043_5	292459.STH456	4.105e-05	55.0	COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,24QMT@186801|Clostridia	186801|Clostridia	S	Branched-chain amino acid transport	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158518_k127_4279043_3	1128421.JAGA01000004_gene2702	1.862e-26	122.0	COG1296@1|root,COG1296@2|Bacteria	2|Bacteria	E	L-valine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158518_k127_4279043_4	345341.KUTG_02467	2.116e-07	62.0	COG3087@1|root,COG3087@2|Bacteria,2IS4S@201174|Actinobacteria,4EC1E@85010|Pseudonocardiales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4279043_1	1382356.JQMP01000004_gene581	5.529e-87	303.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158518_k127_4284190_2	751945.Theos_0497	1.899e-12	77.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158518_k127_4284190_0	1487953.JMKF01000064_gene4752	2.895e-54	213.0	COG0682@1|root,COG0682@2|Bacteria,1G23G@1117|Cyanobacteria	1117|Cyanobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158518_k127_4284190_3	35754.JNYJ01000036_gene3797	7.202e-05	54.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4DDUI@85008|Micromonosporales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158518_k127_4284190_1	1123389.ATXJ01000001_gene694	2.782e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,1WKHQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_4299846_1	1382359.JIAL01000001_gene415	3.867e-100	344.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria,2JHIQ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158518_k127_4299846_3	644282.Deba_0535	8.99e-62	231.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
SRR25158518_k127_4299846_2	485913.Krac_11275	1.364e-92	317.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
SRR25158518_k127_4299846_0	479434.Sthe_0497	2.944e-132	436.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi,27XMK@189775|Thermomicrobia	189775|Thermomicrobia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ChlI
SRR25158518_k127_4302217_1	357808.RoseRS_3251	2.385e-57	208.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi,375I2@32061|Chloroflexia	32061|Chloroflexia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158518_k127_4302217_3	316274.Haur_3842	2.116e-07	62.0	COG0762@1|root,COG0762@2|Bacteria,2G9QH@200795|Chloroflexi,3760D@32061|Chloroflexia	32061|Chloroflexia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158518_k127_4302217_2	316057.RPD_0693	2.432e-11	71.0	COG1872@1|root,COG1872@2|Bacteria,1N6V2@1224|Proteobacteria,2UF67@28211|Alphaproteobacteria,3JZCX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0235 family	MA20_25230	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158518_k127_4302217_0	309801.trd_A0562	0.0	1131.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,27XND@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158518_k127_4335544_7	926554.KI912654_gene4457	5.319e-12	77.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.218	ko:K10710	-	-	R08124	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
SRR25158518_k127_4335544_4	1151122.AQYD01000007_gene1026	6.163e-63	229.0	COG3231@1|root,COG3231@2|Bacteria,2HIED@201174|Actinobacteria,4FP13@85023|Microbacteriaceae	201174|Actinobacteria	J	Phosphotransferase enzyme family	-	-	2.7.1.95	ko:K00897	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
SRR25158518_k127_4335544_3	1179773.BN6_22990	7.167e-80	273.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria,4DYTH@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158518_k127_4335544_1	1173028.ANKO01000128_gene4241	4.487e-128	430.0	COG0064@1|root,COG0064@2|Bacteria,1G0H0@1117|Cyanobacteria,1H7I7@1150|Oscillatoriales	1117|Cyanobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158518_k127_4335544_0	1128421.JAGA01000002_gene1310	4.067e-148	482.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158518_k127_4335544_5	1150398.JIBJ01000012_gene2070	9.079e-36	146.0	COG3832@1|root,COG3832@2|Bacteria,2GY9A@201174|Actinobacteria	201174|Actinobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_4335544_6	195250.CM001776_gene2817	6.682e-28	116.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1GZCX@1129|Synechococcus	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158518_k127_447991_0	324602.Caur_2260	9.374e-136	447.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158518_k127_447991_2	1120971.AUCA01000003_gene1442	3.627e-75	265.0	COG0388@1|root,COG0388@2|Bacteria,1UHWF@1239|Firmicutes,4HEQ4@91061|Bacilli,279EQ@186823|Alicyclobacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158518_k127_447991_1	926569.ANT_07770	4.403e-77	281.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158518_k127_447991_3	489825.LYNGBM3L_44380	1.544e-58	219.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,1H7AW@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158518_k127_447991_4	1268072.PSAB_05940	1.594e-08	59.0	COG0629@1|root,COG0629@2|Bacteria,1W7D8@1239|Firmicutes,4I45T@91061|Bacilli,273GW@186822|Paenibacillaceae	91061|Bacilli	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158518_k127_467754_4	1121920.AUAU01000011_gene161	3.051e-73	264.0	COG0277@1|root,COG0277@2|Bacteria,3Y36Q@57723|Acidobacteria	57723|Acidobacteria	C	PFAM FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158518_k127_467754_7	649638.Trad_0869	5.156e-48	183.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
SRR25158518_k127_467754_6	794903.OPIT5_04600	8.018e-56	205.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158518_k127_467754_8	1713.JOFV01000018_gene213	1.264e-32	136.0	2EJRI@1|root,32U8K@2|Bacteria,2IT18@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158518_k127_467754_9	1120959.ATXF01000009_gene700	0.0007477	48.0	COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4FQG4@85023|Microbacteriaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158518_k127_467754_0	1121946.AUAX01000040_gene5631	2.133e-180	586.0	COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4D93Z@85008|Micromonosporales	201174|Actinobacteria	J	Elongation factor G, domain IV	tetP	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
SRR25158518_k127_467754_2	1160718.SU9_28741	1.523e-75	271.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158518_k127_467754_3	494419.ALPM01000063_gene2256	5.579e-75	259.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,1WC1D@1268|Micrococcaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158518_k127_467754_1	373903.Hore_20600	1.199e-101	349.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158518_k127_467754_5	1120960.ATXG01000001_gene1240	1.996e-70	257.0	COG2723@1|root,COG2723@2|Bacteria,2H2MI@201174|Actinobacteria,4FNAA@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
SRR25158518_k127_487252_1	309801.trd_1139	2.012e-102	340.0	COG0365@1|root,COG0365@2|Bacteria,2G830@200795|Chloroflexi,27XH3@189775|Thermomicrobia	189775|Thermomicrobia	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158518_k127_487252_2	448385.sce4321	5.915e-87	319.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2Z2XK@29|Myxococcales	28221|Deltaproteobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158518_k127_487252_0	331869.BAL199_29475	1.955e-125	424.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,4BP9X@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Biotin carboxylase C-terminal domain	MA20_30205	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158518_k127_488457_1	502025.Hoch_5746	2.183e-56	202.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2YU8U@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
SRR25158518_k127_488457_0	383372.Rcas_3398	6.725e-165	537.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,375CH@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
SRR25158518_k127_495388_0	243164.DET0018	1.578e-24	105.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi,34DFF@301297|Dehalococcoidia	301297|Dehalococcoidia	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_501849_1	324602.Caur_3655	1.97e-81	293.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,3769A@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SRR25158518_k127_501849_2	479434.Sthe_3025	1.052e-78	289.0	COG1169@1|root,COG1169@2|Bacteria,2GADW@200795|Chloroflexi,27Y2P@189775|Thermomicrobia	189775|Thermomicrobia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158518_k127_501849_3	1128421.JAGA01000003_gene2742	7.536e-58	209.0	COG1309@1|root,COG1309@2|Bacteria,2NRTD@2323|unclassified Bacteria	2|Bacteria	K	YsiA-like protein, C-terminal region	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1,TetR_C_4,TetR_N
SRR25158518_k127_501849_5	585502.HMPREF0645_0529	4.913e-30	124.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,2G370@200643|Bacteroidia	976|Bacteroidetes	S	Mg2 transporter-C family protein	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
SRR25158518_k127_501849_4	479434.Sthe_2986	4.154e-57	212.0	COG0569@1|root,COG0569@2|Bacteria,2G8TE@200795|Chloroflexi,27YS6@189775|Thermomicrobia	189775|Thermomicrobia	C	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158518_k127_501849_0	479434.Sthe_2985	8.646e-125	415.0	COG0168@1|root,COG0168@2|Bacteria,2G8FV@200795|Chloroflexi,27YUG@189775|Thermomicrobia	189775|Thermomicrobia	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
SRR25158518_k127_501849_6	1382356.JQMP01000003_gene1959	3.508e-12	73.0	COG0642@1|root,COG2205@2|Bacteria,2GAAW@200795|Chloroflexi,27Z8B@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158518_k127_519291_0	1382306.JNIM01000001_gene3845	6.613e-136	449.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi	200795|Chloroflexi	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158518_k127_519291_1	751945.Theos_1644	2.08e-115	385.0	COG1494@1|root,COG1494@2|Bacteria,1WI3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158518_k127_526042_0	857293.CAAU_1996	1.525e-261	821.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,36DYE@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158518_k127_526042_1	1150474.JQJI01000054_gene1401	1.246e-22	106.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
SRR25158518_k127_526042_2	1298880.AUEV01000010_gene2846	1.83e-08	66.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158518_k127_536477_1	555088.DealDRAFT_0271	8.184e-105	353.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42KYM@68298|Syntrophomonadaceae	186801|Clostridia	H	Aminotransferase class-V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158518_k127_536477_2	525904.Tter_1033	8.69e-88	319.0	COG0482@1|root,COG0482@2|Bacteria,2NNPW@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158518_k127_536477_0	1211114.ALIP01000113_gene866	2.526e-153	505.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1X3MQ@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158518_k127_552672_0	521098.Aaci_1432	1.996e-59	215.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,27888@186823|Alicyclobacillaceae	91061|Bacilli	K	Participates in both transcription termination and antitermination	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158518_k127_552672_1	1051632.TPY_1703	2.913e-14	82.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3WCNN@538999|Clostridiales incertae sedis	186801|Clostridia	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158518_k127_552672_2	525904.Tter_0910	4.861e-13	77.0	COG0532@1|root,COG0532@2|Bacteria,2NNRG@2323|unclassified Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158518_k127_581247_1	525904.Tter_0669	1.545e-124	415.0	COG1404@1|root,COG1404@2|Bacteria,2NQYY@2323|unclassified Bacteria	2|Bacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Inhibitor_I9,PA,Peptidase_S8
SRR25158518_k127_581247_2	1391646.AVSU01000092_gene404	3.284e-06	58.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,25QZI@186804|Peptostreptococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158518_k127_581247_0	1122223.KB890688_gene1647	1.899e-171	545.0	COG1012@1|root,COG1012@2|Bacteria,1WJFH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158518_k127_586078_3	1184609.KILIM_029_00080	3.502e-62	218.0	COG0431@1|root,COG0431@2|Bacteria,2IHWU@201174|Actinobacteria	201174|Actinobacteria	S	fmn reductase	ssuE	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
SRR25158518_k127_586078_0	1386089.N865_18300	1.028e-202	636.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4FEC3@85021|Intrasporangiaceae	201174|Actinobacteria	C	tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_586078_2	369723.Strop_1658	1.864e-118	402.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria,4DHMK@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158518_k127_586078_1	1227352.C173_08696	1.702e-141	469.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,4HEKC@91061|Bacilli,26TSJ@186822|Paenibacillaceae	91061|Bacilli	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SRR25158518_k127_586078_4	1033743.CAES01000032_gene925	5.553e-11	64.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,FR47
SRR25158518_k127_597421_0	552398.HMPREF0866_01412	1.193e-60	216.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3WIDV@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	walR	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_597421_1	479432.Sros_8765	1.946e-47	191.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4EHDZ@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158518_k127_631533_0	243164.DET0766	2.394e-174	569.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi,34CNJ@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	-	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158518_k127_631533_2	35754.JNYJ01000027_gene6130	6.707e-37	153.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4DIPZ@85008|Micromonosporales	201174|Actinobacteria	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158518_k127_631533_3	448385.sce4787	2.09e-10	74.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YUIK@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158518_k127_631533_1	1382356.JQMP01000003_gene1548	4.227e-41	154.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi,27Y9T@189775|Thermomicrobia	189775|Thermomicrobia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SRR25158518_k127_635046_7	1121403.AUCV01000032_gene2901	7.231e-87	295.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158518_k127_635046_9	1304875.JAFZ01000001_gene1078	9.59e-32	137.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158518_k127_635046_0	1128421.JAGA01000003_gene2953	1.619e-309	999.0	COG0366@1|root,COG0366@2|Bacteria,2NQQN@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SRR25158518_k127_635046_2	438753.AZC_4378	3.077e-114	379.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,3F1HK@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158518_k127_635046_6	1385517.N800_06160	3.215e-90	323.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria,1X3WH@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_635046_8	1123261.AXDW01000004_gene2722	6.611e-47	182.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,1S427@1236|Gammaproteobacteria,1XCFN@135614|Xanthomonadales	135614|Xanthomonadales	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K22479	-	-	-	-	ko00000	-	-	-	Acetyltransf_3
SRR25158518_k127_635046_3	471853.Bcav_3864	3.51e-105	367.0	COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria	201174|Actinobacteria	J	Methionine aminopeptidase	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158518_k127_635046_4	861299.J421_4478	4.482e-104	371.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158518_k127_635046_10	767029.HMPREF9154_1844	2.658e-11	77.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158518_k127_635046_5	1445613.JALM01000009_gene898	4.085e-102	346.0	COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4DYM2@85010|Pseudonocardiales	201174|Actinobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158518_k127_635046_11	742738.HMPREF9460_01419	4.272e-10	72.0	COG3708@1|root,COG3708@2|Bacteria,1V51M@1239|Firmicutes,24IWT@186801|Clostridia,26BW7@186813|unclassified Clostridiales	186801|Clostridia	K	Protein of unknown function (DUF3788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
SRR25158518_k127_635046_1	1382356.JQMP01000003_gene2146	4.395e-164	542.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi,27Z2G@189775|Thermomicrobia	189775|Thermomicrobia	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
SRR25158518_k127_635046_14	392499.Swit_1392	1.457e-05	58.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,2KARB@204457|Sphingomonadales	204457|Sphingomonadales	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158518_k127_635046_12	1035308.AQYY01000001_gene1703	2.006e-09	70.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
SRR25158518_k127_635046_13	293826.Amet_3686	3.047e-07	63.0	COG1388@1|root,COG1388@2|Bacteria,1VEKE@1239|Firmicutes,24TUQ@186801|Clostridia,36MQK@31979|Clostridiaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158518_k127_636312_3	1150398.JIBJ01000014_gene2460	2.769e-17	90.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
SRR25158518_k127_636312_2	292415.Tbd_1924	2.143e-18	99.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VW5P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF454)	ybaN	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
SRR25158518_k127_636312_1	935839.JAGJ01000001_gene1307	4.963e-23	114.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4F43W@85017|Promicromonosporaceae	201174|Actinobacteria	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158518_k127_636312_0	479434.Sthe_2774	9.962e-121	423.0	28HJF@1|root,2Z7UK@2|Bacteria,2G862@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_63785_1	1173264.KI913949_gene464	4.169e-90	305.0	COG2084@1|root,COG2084@2|Bacteria,1G1GH@1117|Cyanobacteria,1H8UU@1150|Oscillatoriales	1117|Cyanobacteria	I	NAD binding domain of 6-phosphogluconate dehydrogenase	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158518_k127_63785_0	1340493.JNIF01000003_gene2134	3.824e-112	370.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158518_k127_638765_0	1206726.BAFV01000029_gene2248	5.256e-102	342.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4FXA3@85025|Nocardiaceae	201174|Actinobacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
SRR25158518_k127_638765_1	65497.JODV01000008_gene132	1.835e-47	174.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4E0HP@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_640279_1	1385520.N802_00490	5.685e-48	179.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,4FGFM@85021|Intrasporangiaceae	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158518_k127_640279_3	383372.Rcas_2100	9.092e-09	63.0	2DRW3@1|root,33DCW@2|Bacteria,2G7E0@200795|Chloroflexi,37627@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
SRR25158518_k127_640279_2	1121033.AUCF01000026_gene2960	1.612e-47	186.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2U9QU@28211|Alphaproteobacteria,2JRSK@204441|Rhodospirillales	204441|Rhodospirillales	EH	Aminotransferase	-	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158518_k127_640279_0	1210884.HG799471_gene14601	1.103e-59	211.0	COG0147@1|root,COG0147@2|Bacteria,2IXEN@203682|Planctomycetes	203682|Planctomycetes	EH	component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158518_k127_641013_4	644966.Tmar_1357	7.146e-76	261.0	COG2041@1|root,COG2041@2|Bacteria,1UMMR@1239|Firmicutes,24QVC@186801|Clostridia	186801|Clostridia	S	PFAM Oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158518_k127_641013_3	1340493.JNIF01000003_gene2775	3.547e-86	292.0	COG1216@1|root,COG1216@2|Bacteria,3Y9AS@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158518_k127_641013_9	309801.trd_0490	7.344e-26	121.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,27Y04@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158518_k127_641013_7	1348338.ADILRU_0447	3.762e-37	152.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4FKD7@85023|Microbacteriaceae	201174|Actinobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158518_k127_641013_6	29306.JOBE01000050_gene5792	2.116e-50	206.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158518_k127_641013_5	1304275.C41B8_04291	1.13e-52	193.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,1RQDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	permease	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158518_k127_641013_1	521096.Tpau_4151	4.779e-109	366.0	COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	proV	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158518_k127_641013_8	1347392.CCEZ01000043_gene167	2.37e-32	136.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,36J5S@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158518_k127_641013_0	1128421.JAGA01000002_gene991	2.093e-147	486.0	COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria	2|Bacteria	L	ATP dependent DNA ligase C terminal region	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158518_k127_64216_0	1254432.SCE1572_13050	7.044e-113	374.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,43BBS@68525|delta/epsilon subdivisions,2X6QY@28221|Deltaproteobacteria,2YU79@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158518_k127_64216_1	1121924.ATWH01000002_gene3774	1.87e-71	268.0	COG0664@1|root,COG0664@2|Bacteria,2I8MP@201174|Actinobacteria,4FQMK@85023|Microbacteriaceae	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,cNMP_binding
SRR25158518_k127_64216_2	234267.Acid_0606	4.671e-14	86.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria	57723|Acidobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158518_k127_644039_0	553973.CLOHYLEM_04560	1.337e-64	245.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,21XXY@1506553|Lachnoclostridium	186801|Clostridia	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158518_k127_644039_2	97139.C824_01934	7.569e-41	162.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V73P@1239|Firmicutes,24I5K@186801|Clostridia,36IZ6@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
SRR25158518_k127_644039_1	1395571.TMS3_0114740	1.115e-51	203.0	COG0454@1|root,COG0456@2|Bacteria,1R8G2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
SRR25158518_k127_671702_11	665956.HMPREF1032_01254	2.986e-06	50.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WHP7@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SRR25158518_k127_671702_7	266117.Rxyl_2116	4.324e-47	192.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,2IKKU@201174|Actinobacteria,4CQAR@84995|Rubrobacteria	84995|Rubrobacteria	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
SRR25158518_k127_671702_2	309801.trd_0183	3.183e-87	314.0	COG0107@1|root,COG0107@2|Bacteria,2G5Y2@200795|Chloroflexi,27XVT@189775|Thermomicrobia	189775|Thermomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158518_k127_671702_8	1249627.D779_4186	4.541e-46	178.0	COG0107@1|root,COG0118@1|root,COG0107@2|Bacteria,COG0118@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1X28P@135613|Chromatiales	135613|Chromatiales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K01663	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,His_biosynth
SRR25158518_k127_671702_5	471855.Shel_15260	1.081e-55	219.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CUNW@84998|Coriobacteriia	84998|Coriobacteriia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158518_k127_671702_9	1247649.D560_2483	7.979e-45	178.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,3T1PA@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158518_k127_671702_1	525904.Tter_0659	7.097e-90	317.0	COG0141@1|root,COG0141@2|Bacteria,2NNTS@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158518_k127_671702_3	1121957.ATVL01000008_gene3975	1.554e-72	254.0	COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,47M8W@768503|Cytophagia	976|Bacteroidetes	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158518_k127_671702_10	264732.Moth_2038	1.988e-22	101.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,42GKT@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM TrpR like protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
SRR25158518_k127_671702_6	584708.Apau_2181	4.037e-51	190.0	COG0106@1|root,COG0118@1|root,COG0106@2|Bacteria,COG0118@2|Bacteria,3TAX8@508458|Synergistetes	508458|Synergistetes	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158518_k127_671702_0	1094508.Tsac_0974	4.732e-187	609.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42FPS@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM Translation elongation factor	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158518_k127_671702_4	1191523.MROS_0745	1.05e-66	232.0	COG0217@1|root,COG0217@2|Bacteria	2|Bacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158518_k127_688440_1	1144275.COCOR_06250	9.239e-66	230.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
SRR25158518_k127_688440_13	525909.Afer_1639	7.628e-09	65.0	COG3340@1|root,COG3340@2|Bacteria,2HH0B@201174|Actinobacteria,4CP0Q@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SRR25158518_k127_688440_9	365528.KB891102_gene4599	7.761e-25	119.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_688440_11	180281.CPCC7001_1073	3.433e-21	108.0	COG1075@1|root,COG1075@2|Bacteria,1FZWY@1117|Cyanobacteria,22RTF@167375|Cyanobium	1117|Cyanobacteria	S	with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF915,PGAP1
SRR25158518_k127_688440_7	1051632.TPY_2536	1.861e-29	124.0	COG1433@1|root,COG1433@2|Bacteria,1W45F@1239|Firmicutes	1239|Firmicutes	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
SRR25158518_k127_688440_5	1246448.ANAZ01000002_gene3996	4.868e-40	151.0	COG1695@1|root,COG1695@2|Bacteria,2IQ51@201174|Actinobacteria,4EPI6@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158518_k127_688440_2	397278.JOJN01000007_gene3362	8.699e-58	216.0	COG0604@1|root,COG0604@2|Bacteria,2I8SZ@201174|Actinobacteria,4DUXX@85009|Propionibacteriales	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_688440_10	685035.ADAE01000003_gene2824	2.56e-21	103.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,2K6D0@204457|Sphingomonadales	204457|Sphingomonadales	P	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
SRR25158518_k127_688440_6	1123368.AUIS01000035_gene76	1.466e-33	139.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,1SYEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC,ZnuA
SRR25158518_k127_688440_4	195250.CM001776_gene1034	2.632e-42	174.0	COG1030@1|root,COG1030@2|Bacteria,1G4Z9@1117|Cyanobacteria,1H1D9@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
SRR25158518_k127_688440_3	710111.FraQA3DRAFT_0341	5.902e-48	186.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4ESTT@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SRR25158518_k127_688440_0	309801.trd_1149	1.315e-88	308.0	COG1131@1|root,COG1131@2|Bacteria,2G7SA@200795|Chloroflexi,27XY4@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158518_k127_688440_8	926554.KI912660_gene2385	3.108e-29	123.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SRR25158518_k127_688440_12	521011.Mpal_1285	5.866e-11	74.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,GSDH
SRR25158518_k127_688440_14	243365.CV_0603	2.525e-08	55.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,2KQDS@206351|Neisseriales	206351|Neisseriales	C	oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158518_k127_688845_7	1380390.JIAT01000009_gene517	6.298e-16	84.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158518_k127_688845_2	420246.GTNG_1650	7.147e-80	295.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli,1WFU6@129337|Geobacillus	91061|Bacilli	S	ABC1 family	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
SRR25158518_k127_688845_6	1229520.ADIAL_1895	3.769e-20	103.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,27FRW@186828|Carnobacteriaceae	91061|Bacilli	S	AI-2E family transporter	yueF	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_688845_8	1828.JOKB01000053_gene5021	2.751e-13	83.0	COG0392@1|root,COG0392@2|Bacteria,2ICMJ@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158518_k127_688845_3	1463857.JOFZ01000009_gene6247	5.375e-74	265.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	eis	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158518_k127_688845_1	105422.BBPM01000097_gene5229	3.666e-97	335.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,2NH21@228398|Streptacidiphilus	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158518_k127_688845_5	1305732.JAGG01000001_gene1689	6.786e-31	142.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4FKUH@85023|Microbacteriaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158518_k127_688845_0	420324.KI912037_gene2409	1.607e-105	351.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,1JS1S@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	TrkA-C domain	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
SRR25158518_k127_691067_1	1121422.AUMW01000005_gene585	2.972e-50	190.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,260PC@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158518_k127_691067_0	1487923.DP73_07150	1.623e-62	228.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158518_k127_699071_3	573413.Spirs_0310	5.052e-18	86.0	COG0407@1|root,COG0407@2|Bacteria,2JA7B@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
SRR25158518_k127_699071_2	1410624.JNKK01000041_gene1211	2.034e-38	153.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
SRR25158518_k127_699071_1	1499967.BAYZ01000171_gene5549	1.658e-55	222.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158518_k127_699071_0	452637.Oter_4341	3.708e-118	400.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,46VH9@74201|Verrucomicrobia,3K8AT@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445
SRR25158518_k127_700985_1	246200.SPOA0210	3.669e-33	139.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria,4NB15@97050|Ruegeria	28211|Alphaproteobacteria	EG	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
SRR25158518_k127_700985_0	485913.Krac_5061	6.415e-142	460.0	COG2141@1|root,COG2141@2|Bacteria,2G5JS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_700985_2	1382304.JNIL01000001_gene1680	2.242e-06	55.0	COG2223@1|root,COG2223@2|Bacteria,1UJR3@1239|Firmicutes,4ITDR@91061|Bacilli	91061|Bacilli	P	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
SRR25158518_k127_708064_0	485913.Krac_8302	2.327e-183	584.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158518_k127_708064_1	592015.HMPREF1705_01556	1.684e-66	244.0	COG2021@1|root,COG2021@2|Bacteria,3TAC1@508458|Synergistetes	508458|Synergistetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
SRR25158518_k127_725272_1	909613.UO65_1308	1.36e-42	174.0	COG0477@1|root,COG2814@2|Bacteria,2I5F8@201174|Actinobacteria,4E5MI@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158518_k127_725272_2	981369.JQMJ01000004_gene2672	2.812e-23	108.0	COG0640@1|root,COG0640@2|Bacteria,2GUG4@201174|Actinobacteria,2NIN4@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158518_k127_725272_0	926550.CLDAP_40500	3.147e-66	239.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158518_k127_735578_11	118163.Ple7327_1591	5.133e-34	151.0	COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,3VIQD@52604|Pleurocapsales	1117|Cyanobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158518_k127_735578_12	1125863.JAFN01000001_gene296	5.889e-33	148.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158518_k127_735578_15	518766.Rmar_1812	6.552e-20	94.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,1FJMR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158518_k127_735578_16	439235.Dalk_2643	1.47e-16	92.0	COG3884@1|root,COG3884@2|Bacteria,1RK7J@1224|Proteobacteria,42SWW@68525|delta/epsilon subdivisions,2WPK8@28221|Deltaproteobacteria,2MK3P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
SRR25158518_k127_735578_5	552811.Dehly_1111	5.239e-70	259.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,34CT3@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HisKA_7TM
SRR25158518_k127_735578_4	1380347.JNII01000007_gene500	1.453e-80	280.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4EU25@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158518_k127_735578_8	1150864.MILUP08_44518	5.207e-50	186.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria,4DA7B@85008|Micromonosporales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158518_k127_735578_1	1211815.CBYP010000012_gene527	1.017e-91	306.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4EX55@85013|Frankiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
SRR25158518_k127_735578_3	1496688.ER33_00820	1.375e-81	284.0	COG0500@1|root,COG2226@2|Bacteria,1G1WF@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
SRR25158518_k127_735578_18	1365176.N186_08530	2.374e-05	57.0	arCOG09752@1|root,arCOG09752@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_735578_7	661478.OP10G_1218	3.374e-58	208.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158518_k127_735578_9	448385.sce8846	1.437e-48	183.0	COG0640@1|root,COG0640@2|Bacteria,1RH4V@1224|Proteobacteria,43AH1@68525|delta/epsilon subdivisions,2X5X1@28221|Deltaproteobacteria,2Z038@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158518_k127_735578_17	1122138.AQUZ01000005_gene2564	3.51e-15	83.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158518_k127_735578_19	1120950.KB892720_gene1917	0.0002112	52.0	COG0500@1|root,COG2226@2|Bacteria,2IP2P@201174|Actinobacteria,4DWM9@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158518_k127_735578_0	1380347.JNII01000006_gene1592	2.921e-134	461.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_12
SRR25158518_k127_735578_2	68570.DC74_431	7.14e-88	306.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158518_k127_735578_14	518766.Rmar_1854	3.755e-26	123.0	COG0438@1|root,COG0438@2|Bacteria,4NH7K@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158518_k127_735578_6	710696.Intca_0085	4.05e-65	237.0	COG2334@1|root,COG2334@2|Bacteria,2GQU8@201174|Actinobacteria,4FG7U@85021|Intrasporangiaceae	201174|Actinobacteria	S	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158518_k127_735578_13	1121927.GOHSU_46_00230	1.168e-29	128.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4GCR1@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158518_k127_735578_20	251221.35213566	0.0002981	53.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_756270_3	675635.Psed_0976	7.66e-21	100.0	COG1309@1|root,COG1309@2|Bacteria,2HKNV@201174|Actinobacteria,4E2JP@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158518_k127_756270_4	485913.Krac_3903	8.372e-15	81.0	2EACU@1|root,334GQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158518_k127_756270_1	1463853.JOHW01000008_gene818	4.862e-56	202.0	COG0491@1|root,COG0491@2|Bacteria,2GJ6X@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158518_k127_756270_0	1120960.ATXG01000001_gene1075	7.126e-202	643.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4FMB6@85023|Microbacteriaceae	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158518_k127_756270_2	323261.Noc_1447	3.102e-31	133.0	COG4244@1|root,COG4244@2|Bacteria,1RF4K@1224|Proteobacteria,1S637@1236|Gammaproteobacteria,1X1IA@135613|Chromatiales	135613|Chromatiales	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158518_k127_797973_4	479434.Sthe_2778	2.438e-69	248.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158518_k127_797973_7	525904.Tter_1481	5.361e-33	142.0	COG2265@1|root,COG2265@2|Bacteria,2NRDB@2323|unclassified Bacteria	2|Bacteria	J	Methyltransferase domain	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Methyltransf_21,Methyltransf_25,Methyltransf_31
SRR25158518_k127_797973_9	929712.KI912613_gene2319	7.834e-19	97.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4CQMI@84995|Rubrobacteria	84995|Rubrobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158518_k127_797973_3	525904.Tter_2236	3.731e-73	269.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158518_k127_797973_1	479434.Sthe_1402	6.305e-84	300.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,27XNE@189775|Thermomicrobia	189775|Thermomicrobia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158518_k127_797973_0	1128421.JAGA01000002_gene1211	1.805e-116	383.0	COG0714@1|root,COG0714@2|Bacteria,2NQNN@2323|unclassified Bacteria	2|Bacteria	S	AAA domain (dynein-related subfamily)	coxD	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158518_k127_797973_2	926560.KE387023_gene3595	8.443e-82	301.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
SRR25158518_k127_797973_5	1385520.N802_16795	8.178e-47	182.0	COG0823@1|root,COG0823@2|Bacteria,2HXVS@201174|Actinobacteria,4FHZG@85021|Intrasporangiaceae	201174|Actinobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158518_k127_797973_8	867845.KI911784_gene210	4.752e-32	144.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
SRR25158518_k127_797973_10	1294273.roselon_00040	2.717e-08	67.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158518_k127_797973_6	525904.Tter_1417	3.091e-34	141.0	COG0303@1|root,COG0303@2|Bacteria,2NR4P@2323|unclassified Bacteria	2|Bacteria	H	'Molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_799785_0	66377.JOBH01000031_gene4502	7.385e-195	623.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158518_k127_799785_2	1463917.JODC01000007_gene7699	9.806e-49	177.0	COG0346@1|root,COG0346@2|Bacteria,2IIMV@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,TetR_N
SRR25158518_k127_799785_1	485913.Krac_9981	2.554e-142	464.0	COG1012@1|root,COG1012@2|Bacteria,2G83P@200795|Chloroflexi	200795|Chloroflexi	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SRR25158518_k127_819638_3	1206732.BAGD01000118_gene5271	2.526e-30	126.0	2DNTJ@1|root,32Z2U@2|Bacteria,2I8BW@201174|Actinobacteria,4GA2K@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158518_k127_819638_1	1122182.KB903814_gene3489	7.113e-54	205.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria,4DIKD@85008|Micromonosporales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158518_k127_819638_0	926560.KE387023_gene3024	1.258e-71	263.0	COG0604@1|root,COG0604@2|Bacteria,1WM8H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158518_k127_819638_2	1108045.GORHZ_047_00170	4.665e-40	158.0	COG2865@1|root,COG2865@2|Bacteria,2IFGR@201174|Actinobacteria,4GAST@85026|Gordoniaceae	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
SRR25158518_k127_820670_5	765420.OSCT_1698	0.0001222	46.0	COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi,37758@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SRR25158518_k127_820670_4	357808.RoseRS_0174	4.235e-18	89.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158518_k127_820670_0	357808.RoseRS_0174	3.07e-68	244.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158518_k127_820670_3	935866.JAER01000005_gene173	5.22e-21	99.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4DRC8@85009|Propionibacteriales	201174|Actinobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158518_k127_820670_1	357808.RoseRS_1298	1.422e-63	222.0	COG2343@1|root,COG2343@2|Bacteria,2GARM@200795|Chloroflexi,3775Q@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158518_k127_820670_2	298654.FraEuI1c_6150	3.062e-52	188.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria,4ESEV@85013|Frankiales	201174|Actinobacteria	V	PFAM Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158518_k127_826286_3	1382356.JQMP01000004_gene105	6.035e-20	100.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi,27YB6@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158518_k127_826286_4	926569.ANT_02430	1.345e-13	84.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_826286_1	1128421.JAGA01000003_gene3259	1.1e-62	223.0	COG2197@1|root,COG2197@2|Bacteria,2NR2Y@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158518_k127_826286_2	1463881.KL591003_gene5844	3.297e-40	158.0	COG2267@1|root,COG2267@2|Bacteria,2IAIJ@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158518_k127_826286_0	309799.DICTH_1516	8.236e-108	364.0	COG1210@1|root,COG1210@2|Bacteria	2|Bacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
SRR25158518_k127_835154_3	667014.Thein_1559	2.301e-47	174.0	COG0191@1|root,COG0191@2|Bacteria,2GHBA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
SRR25158518_k127_835154_4	1464048.JNZS01000010_gene5078	1.286e-30	134.0	COG3153@1|root,COG3153@2|Bacteria,2IKX0@201174|Actinobacteria,4DEKI@85008|Micromonosporales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824,ko:K09964	-	-	-	-	ko00000,ko01000	-	-	-	ACT_3,ACT_7,Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
SRR25158518_k127_835154_0	526225.Gobs_0108	1.796e-104	356.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria,4EUG4@85013|Frankiales	201174|Actinobacteria	J	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158518_k127_835154_1	926569.ANT_03430	1.189e-86	297.0	COG1409@1|root,COG1409@2|Bacteria,2G88X@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158518_k127_835154_2	656024.FsymDg_0960	7.968e-55	203.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4ERCV@85013|Frankiales	201174|Actinobacteria	G	PFAM Inositol monophosphatase	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158518_k127_841246_3	760117.JN27_13675	7.565e-72	254.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158518_k127_841246_1	204669.Acid345_1269	1.054e-118	407.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158518_k127_841246_2	357808.RoseRS_2549	1.825e-98	349.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158518_k127_841246_9	1500894.JQNN01000001_gene3291	2.353e-05	55.0	COG3595@1|root,COG3595@2|Bacteria,1N9QF@1224|Proteobacteria,2WC95@28216|Betaproteobacteria,47761@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
SRR25158518_k127_841246_8	83332.Rv0582	2.326e-23	108.0	COG2402@1|root,COG2402@2|Bacteria,2HZHQ@201174|Actinobacteria,23BTY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158518_k127_841246_10	247156.NFA_23740	2.748e-05	51.0	2ABAD@1|root,310QY@2|Bacteria,2HI67@201174|Actinobacteria,4G2YU@85025|Nocardiaceae	201174|Actinobacteria	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3
SRR25158518_k127_841246_0	246197.MXAN_1407	2.694e-139	455.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,42Q5H@68525|delta/epsilon subdivisions,2WKW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158518_k127_841246_5	1382306.JNIM01000001_gene1577	1.21e-57	210.0	COG1120@1|root,COG1120@2|Bacteria,2G6QS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158518_k127_841246_4	552811.Dehly_0716	6.855e-69	249.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi,34CYV@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158518_k127_841246_6	926569.ANT_02530	1.362e-47	184.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158518_k127_842094_1	675635.Psed_3596	5.071e-11	73.0	2DGKW@1|root,2ZWET@2|Bacteria,2HSG2@201174|Actinobacteria,4EDKS@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_842094_0	1408254.T458_23490	1.299e-171	552.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,275MV@186822|Paenibacillaceae	91061|Bacilli	L	Domain of unknown function (DUF1998)	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158518_k127_854555_2	1123320.KB889707_gene7991	0.0005122	52.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria	201174|Actinobacteria	CP	ABC-type Na efflux pump, permease	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158518_k127_854555_0	1445613.JALM01000041_gene1723	1.943e-93	318.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria,4DX3X@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158518_k127_854555_1	521011.Mpal_1285	1.959e-15	78.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,GSDH
SRR25158518_k127_873371_2	1172179.AUKV01000016_gene2197	1.56e-86	295.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria	201174|Actinobacteria	G	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158518_k127_873371_1	1380390.JIAT01000015_gene5744	1.613e-135	446.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4CPGS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158518_k127_873371_0	1089544.KB912942_gene2945	4.892e-149	483.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,4EE1P@85010|Pseudonocardiales	201174|Actinobacteria	S	alpha/beta hydrolase fold	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
SRR25158518_k127_873371_4	1121918.ARWE01000001_gene2935	2.219e-56	213.0	COG5557@1|root,COG5557@2|Bacteria,1R54P@1224|Proteobacteria,42N9S@68525|delta/epsilon subdivisions,2WNKD@28221|Deltaproteobacteria,43U9I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
SRR25158518_k127_873371_3	589924.Ferp_1438	1.251e-66	248.0	COG0437@1|root,arCOG01500@2157|Archaea,2XXPU@28890|Euryarchaeota,24691@183980|Archaeoglobi	183980|Archaeoglobi	C	4Fe-4S dicluster domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4,Fer4_11
SRR25158518_k127_873371_7	1515746.HR45_09395	2.556e-12	79.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RYPM@1236|Gammaproteobacteria,2Q8MP@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
SRR25158518_k127_873371_5	1128421.JAGA01000002_gene1765	1.86e-35	145.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
SRR25158518_k127_873371_6	1128421.JAGA01000002_gene963	8.086e-30	136.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158518_k127_873371_8	1120959.ATXF01000005_gene1353	3.701e-12	69.0	2BVHU@1|root,32QW6@2|Bacteria,2HRWT@201174|Actinobacteria	201174|Actinobacteria	S	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158518_k127_880118_1	1245471.PCA10_30630	8.715e-162	533.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158518_k127_880118_3	1112217.PPL19_17745	8.916e-31	126.0	COG3871@1|root,COG3871@2|Bacteria,1RI2W@1224|Proteobacteria	1224|Proteobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
SRR25158518_k127_880118_0	926569.ANT_17590	3.195e-282	916.0	COG3459@1|root,COG3459@2|Bacteria,2G9NQ@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_880118_2	886293.Sinac_4035	2.809e-50	192.0	COG3210@1|root,COG4655@1|root,COG3210@2|Bacteria,COG4655@2|Bacteria,2J30Y@203682|Planctomycetes	203682|Planctomycetes	U	Extracellular nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP
SRR25158518_k127_880677_12	1122939.ATUD01000001_gene487	8.042e-23	102.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4CPZC@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
SRR25158518_k127_880677_9	28444.JODQ01000006_gene493	4.739e-51	190.0	COG1011@1|root,COG1011@2|Bacteria,2GN3E@201174|Actinobacteria,4EN9J@85012|Streptosporangiales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158518_k127_880677_5	1348338.ADILRU_2460	3.052e-98	338.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4FN71@85023|Microbacteriaceae	201174|Actinobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158518_k127_880677_8	1121946.AUAX01000003_gene1447	2.581e-73	258.0	COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria,4DIAN@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158518_k127_880677_6	1121946.AUAX01000003_gene1448	3.602e-87	316.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2I98G@201174|Actinobacteria,4DA46@85008|Micromonosporales	201174|Actinobacteria	JPQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_880677_4	1122611.KB904029_gene5250	3.034e-118	392.0	COG1171@1|root,COG1171@2|Bacteria,2I8ZW@201174|Actinobacteria,4EIBZ@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
SRR25158518_k127_880677_13	298653.Franean1_2270	1.565e-08	66.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4EW66@85013|Frankiales	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158518_k127_880677_10	688245.CtCNB1_0566	1.288e-49	183.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2VM2U@28216|Betaproteobacteria,4AD3M@80864|Comamonadaceae	28216|Betaproteobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
SRR25158518_k127_880677_7	1440053.JOEI01000015_gene5526	7.57e-85	287.0	COG1802@1|root,COG1802@2|Bacteria,2GMJX@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SRR25158518_k127_880677_0	1155718.KB891951_gene4538	1.961e-178	569.0	COG3938@1|root,COG3938@2|Bacteria,2GM47@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the proline racemase family	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
SRR25158518_k127_880677_3	1440053.JOEI01000015_gene5524	7.645e-149	481.0	COG0329@1|root,COG0446@1|root,COG0329@2|Bacteria,COG0446@2|Bacteria,2GJM6@201174|Actinobacteria	201174|Actinobacteria	E	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
SRR25158518_k127_880677_1	58344.JOEL01000001_gene451	3.55e-178	572.0	COG0446@1|root,COG0446@2|Bacteria,2GJM6@201174|Actinobacteria	201174|Actinobacteria	E	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
SRR25158518_k127_880677_11	68219.JNXI01000004_gene2642	1.583e-31	139.0	COG3383@1|root,COG3383@2|Bacteria,2GSHP@201174|Actinobacteria	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
SRR25158518_k127_880677_2	1440053.JOEI01000015_gene5522	2.504e-152	488.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158518_k127_911178_1	331869.BAL199_16153	1.605e-28	123.0	COG1116@1|root,COG1116@2|Bacteria,1P4HB@1224|Proteobacteria,2TUY9@28211|Alphaproteobacteria,4BPVG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158518_k127_911178_0	926550.CLDAP_24790	1.661e-69	256.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5	ko:K00848,ko:K00851,ko:K00854,ko:K00862	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158518_k127_911178_2	521096.Tpau_3637	7.049e-25	106.0	COG0520@1|root,COG0520@2|Bacteria,2GP7W@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158518_k127_922859_1	1122611.KB903963_gene4852	3.411e-41	155.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4EJ6F@85012|Streptosporangiales	201174|Actinobacteria	S	Nickel-containing superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158518_k127_922859_0	953739.SVEN_0221	3.683e-63	232.0	COG1708@1|root,COG1708@2|Bacteria,2I8HB@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4111)	-	-	2.7.7.47	ko:K00984	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2
SRR25158518_k127_922859_2	1125863.JAFN01000001_gene376	5.334e-12	73.0	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,42SCJ@68525|delta/epsilon subdivisions,2WPGQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CYTH	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
SRR25158518_k127_928063_1	273677.BW34_00369	8.871e-21	107.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4FKCT@85023|Microbacteriaceae	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158518_k127_928063_0	357808.RoseRS_2863	7.406e-108	362.0	COG0540@1|root,COG0540@2|Bacteria,2G6GU@200795|Chloroflexi,376MF@32061|Chloroflexia	32061|Chloroflexia	F	PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158518_k127_928063_2	1074488.AGBX01000007_gene1401	4.218e-18	84.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4FBF2@85020|Dermabacteraceae	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158518_k127_941583_2	1382356.JQMP01000003_gene2395	1.7e-19	104.0	COG5621@1|root,COG5621@2|Bacteria,2G6EI@200795|Chloroflexi,27YRR@189775|Thermomicrobia	189775|Thermomicrobia	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158518_k127_941583_0	485913.Krac_7571	7.846e-201	650.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM MMPL domain protein	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158518_k127_941583_1	709986.Deima_1983	7.082e-25	108.0	COG1509@1|root,COG1509@2|Bacteria,1WKKI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM KamA family protein	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C,Radical_SAM
SRR25158518_k127_942140_6	1394178.AWOO02000055_gene827	2.369e-17	87.0	292KZ@1|root,2ZQ4W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_942140_1	211165.AJLN01000116_gene3220	1.946e-57	221.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SRR25158518_k127_942140_5	1944.JOAZ01000031_gene344	6.198e-23	112.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4191Z@629295|Streptomyces griseus group	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4
SRR25158518_k127_942140_2	290397.Adeh_1997	6.836e-29	128.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,42PU2@68525|delta/epsilon subdivisions,2X60T@28221|Deltaproteobacteria,2Z327@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158518_k127_942140_0	485913.Krac_12111	2.832e-74	272.0	COG1022@1|root,COG1022@2|Bacteria,2G5S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158518_k127_942140_3	1206726.BAFV01000039_gene2832	2.075e-25	119.0	COG0785@1|root,COG0785@2|Bacteria,2IMP9@201174|Actinobacteria,4G4DA@85025|Nocardiaceae	201174|Actinobacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_942140_4	1077974.GOEFS_038_00140	4.961e-24	120.0	COG2865@1|root,COG2865@2|Bacteria,2IFGR@201174|Actinobacteria,4GAST@85026|Gordoniaceae	201174|Actinobacteria	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
SRR25158518_k127_942694_6	1177594.MIC448_190013	7.092e-14	79.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	ko:K21919	-	-	-	-	ko00000,ko04121	-	-	-	Pentapeptide,Pentapeptide_4
SRR25158518_k127_942694_3	446466.Cfla_1938	6.418e-35	151.0	COG0363@1|root,COG4122@1|root,COG0363@2|Bacteria,COG4122@2|Bacteria,2GMQ2@201174|Actinobacteria,4F0XH@85016|Cellulomonadaceae	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158518_k127_942694_4	867845.KI911784_gene3681	8.588e-28	132.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia	32061|Chloroflexia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158518_k127_942694_0	309801.trd_1143	3.13e-203	648.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158518_k127_942694_1	479434.Sthe_2435	1.772e-114	387.0	COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia	189775|Thermomicrobia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158518_k127_942694_5	58123.JOFJ01000016_gene4107	2.571e-18	97.0	COG3147@1|root,COG3147@2|Bacteria,2ID4R@201174|Actinobacteria,4EHHH@85012|Streptosporangiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158518_k127_942694_2	661478.OP10G_4092	9.89e-48	176.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2621	LacAB_rpiB
SRR25158518_k127_946615_2	1445613.JALM01000020_gene4722	1.642e-37	147.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E3AX@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158518_k127_946615_1	1123023.JIAI01000003_gene2648	3.494e-68	255.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4E1EZ@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158518_k127_946615_0	1123023.JIAI01000003_gene2647	4.443e-210	665.0	COG4670@1|root,COG4670@2|Bacteria	2|Bacteria	I	ketone body catabolic process	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158518_k127_949192_3	1382306.JNIM01000001_gene1619	6.72e-13	73.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158518_k127_949192_1	357808.RoseRS_2217	5.181e-50	188.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,375PN@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158518_k127_949192_0	1382306.JNIM01000001_gene2555	3.753e-130	429.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158518_k127_949192_2	926569.ANT_09370	1.482e-34	149.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
SRR25158518_k127_955465_2	1297742.A176_01865	4.866e-31	143.0	COG1012@1|root,COG1012@2|Bacteria,1R528@1224|Proteobacteria,433YD@68525|delta/epsilon subdivisions,2X42A@28221|Deltaproteobacteria,2YY1Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.5	ko:K00129	ko00010,ko00340,ko00350,ko00360,ko00410,ko00980,ko00982,ko01100,ko01110,ko01120,ko05204,map00010,map00340,map00350,map00360,map00410,map00980,map00982,map01100,map01110,map01120,map05204	-	R00711,R00904,R02536,R02537,R02695,R02697,R03300,R03302,R04882,R04883,R04888,R04889,R04891,R04892,R04996,R07104,R08282,R08283,R08307	RC00047,RC00080,RC00242,RC01735	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158518_k127_955465_1	100226.SCO4051	4.948e-55	198.0	COG3542@1|root,COG3542@2|Bacteria,2IFG5@201174|Actinobacteria	201174|Actinobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
SRR25158518_k127_955465_0	582744.Msip34_2459	1.983e-172	559.0	COG0493@1|root,COG1902@1|root,COG0493@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VJ6V@28216|Betaproteobacteria,2KM7C@206350|Nitrosomonadales	206350|Nitrosomonadales	CE	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
SRR25158518_k127_962094_0	292459.STH1417	9.79e-117	386.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia	186801|Clostridia	E	PFAM DAHP synthetase I	aroF1	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158518_k127_962094_1	1382230.ASAP_0483	5.813e-71	252.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,2JPAD@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158518_k127_964191_0	926550.CLDAP_11410	4.905e-38	162.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158518_k127_964191_2	290397.Adeh_1232	1.717e-22	106.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158518_k127_964191_3	485913.Krac_12283	1.738e-06	61.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,CBM_3,CBM_4_9,Calx-beta,F5_F8_type_C,GSDH,PA14,fn3
SRR25158518_k127_964191_1	1382306.JNIM01000001_gene244	1.056e-28	119.0	COG0849@1|root,COG0849@2|Bacteria	2|Bacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
SRR25158518_k127_965071_0	309801.trd_0102	7.632e-127	424.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,27XZ8@189775|Thermomicrobia	189775|Thermomicrobia	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158518_k127_965071_1	743721.Psesu_2499	1.36e-09	59.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1X41Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158518_k127_979881_0	316274.Haur_3105	3.861e-155	505.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	scpD	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
SRR25158518_k127_979881_1	479434.Sthe_0331	6.853e-33	139.0	COG0671@1|root,COG0671@2|Bacteria,2G8YH@200795|Chloroflexi,27YK3@189775|Thermomicrobia	189775|Thermomicrobia	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SRR25158518_k127_994615_1	670487.Ocepr_1968	8.069e-36	147.0	COG1528@1|root,COG1528@2|Bacteria,1WK4S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Iron-storage protein	-	-	1.16.3.1,1.16.3.2	ko:K02217,ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158518_k127_994615_0	469371.Tbis_0952	3.789e-47	183.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4DYBZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
## 2453 queries scanned
## Total time (seconds): 6.342391014099121
## Rate: 386.76 q/s