## Mon Dec 15 17:57:37 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158527_bin.16.fa -m mmseqs --itype genome -o SRR25158527_bin.16 --output_dir /data/result/bins/wyx/egg/SRR25158527_bin.16 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158527_k127_1003702_0	1123239.KB898632_gene2238	9.953e-133	438.0	COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,4HCJ1@91061|Bacilli	91061|Bacilli	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III
SRR25158527_k127_1003702_1	1304883.KI912532_gene2389	3.117e-57	203.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KWIF@206389|Rhodocyclales	206389|Rhodocyclales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158527_k127_1005053_2	1122604.JONR01000001_gene1788	1.821e-05	53.0	28SNC@1|root,2ZEYK@2|Bacteria,1P89G@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
SRR25158527_k127_1005053_0	47839.CCAU010000011_gene5193	1.321e-56	211.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1005053_1	1121106.JQKB01000017_gene4798	4.304e-46	176.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_1009278_0	550540.Fbal_1546	4.546e-108	356.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,1RS83@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158527_k127_1009278_1	485913.Krac_8169	1.242e-26	113.0	COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158527_k127_1009507_1	383372.Rcas_3626	2.388e-68	248.0	COG0477@1|root,COG0477@2|Bacteria,2GA6R@200795|Chloroflexi,3782R@32061|Chloroflexia	32061|Chloroflexia	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_1009507_0	1254432.SCE1572_47310	3.094e-91	309.0	COG1475@1|root,COG1475@2|Bacteria,1Q2AH@1224|Proteobacteria,437X8@68525|delta/epsilon subdivisions,2X9QN@28221|Deltaproteobacteria,2YUMN@29|Myxococcales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158527_k127_1011245_1	237368.SCABRO_01997	1.692e-135	447.0	COG1007@1|root,COG1007@2|Bacteria,2IXC6@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158527_k127_1011245_0	1125863.JAFN01000001_gene2409	8.036e-185	592.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158527_k127_1011245_2	1346330.M472_21960	7.078e-15	77.0	COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia	976|Bacteroidetes	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158527_k127_1016472_2	526222.Desal_0224	1.468e-32	143.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2M7YN@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SRR25158527_k127_1016472_1	696369.KI912183_gene526	5.998e-37	147.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,261XP@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158527_k127_1016472_0	237368.SCABRO_01504	2.188e-77	264.0	COG0659@1|root,COG0659@2|Bacteria,2IX8K@203682|Planctomycetes	203682|Planctomycetes	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
SRR25158527_k127_10216_2	344747.PM8797T_13690	4.407e-35	139.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2IWZA@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,ABC_tran
SRR25158527_k127_10216_0	314230.DSM3645_08352	5.233e-110	364.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2IWZA@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,ABC_tran
SRR25158527_k127_10216_1	1267534.KB906755_gene4491	8.007e-78	274.0	COG1566@1|root,COG1566@2|Bacteria,3Y53G@57723|Acidobacteria	57723|Acidobacteria	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
SRR25158527_k127_1028872_1	266117.Rxyl_1559	1.417e-35	151.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,4CTF3@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_1028872_0	1380394.JADL01000009_gene3308	4.698e-81	278.0	28JPA@1|root,2Z9FC@2|Bacteria,1PN1F@1224|Proteobacteria,2TSKX@28211|Alphaproteobacteria,2JUBG@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1029668_0	1201288.M900_2721	1.136e-106	360.0	COG2159@1|root,COG2159@2|Bacteria,1R7E1@1224|Proteobacteria,42S40@68525|delta/epsilon subdivisions,2WNAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_1029769_0	1118235.CAJH01000040_gene2575	4.034e-91	314.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,1RNZM@1236|Gammaproteobacteria,1X4Z4@135614|Xanthomonadales	135614|Xanthomonadales	M	protein involved in outer membrane biogenesis	asmA	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
SRR25158527_k127_1034931_0	1500259.JQLD01000010_gene4823	1.541e-65	238.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2TU37@28211|Alphaproteobacteria,4BCB2@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_1034931_1	443152.MDG893_15260	1.467e-08	61.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1035077_1	1105367.CG50_06070	1.091e-08	66.0	COG0715@1|root,COG0715@2|Bacteria,1MWC5@1224|Proteobacteria,2TSS8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1035077_0	1453505.JASY01000002_gene2884	7.06e-82	278.0	COG1738@1|root,COG1738@2|Bacteria,4NNPU@976|Bacteroidetes,1I2GG@117743|Flavobacteriia,2NU67@237|Flavobacterium	976|Bacteroidetes	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
SRR25158527_k127_1036220_3	644966.Tmar_R0053	2.099e-26	116.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WD6Q@538999|Clostridiales incertae sedis	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158527_k127_1036220_0	671143.DAMO_3033	1.357e-136	443.0	COG0407@1|root,COG1587@1|root,COG0407@2|Bacteria,COG1587@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,4.1.1.37,4.2.1.75	ko:K01599,ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194,R03197,R04972	RC00003,RC00871,RC00872,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	HEM4,Trans_reg_C,URO-D
SRR25158527_k127_1036220_2	671143.DAMO_3034	1.418e-94	319.0	COG0276@1|root,COG0276@2|Bacteria,2NQ0V@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
SRR25158527_k127_1036220_1	671143.DAMO_3035	2.42e-128	426.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
SRR25158527_k127_1047038_2	1547437.LL06_00335	2.162e-14	78.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,43IZ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	4.1.1.55	ko:K04102	ko00624,ko01100,ko01120,map00624,map01100,map01120	M00623	R01635,R05375	RC00390	ko00000,ko00001,ko00002,ko01000	-	-	-	NMT1
SRR25158527_k127_1047038_1	1449044.JMLE01000018_gene1661	8.26e-16	90.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1047038_0	296591.Bpro_3170	4.973e-30	131.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,4A9Y6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_1047514_0	1231391.AMZF01000003_gene3114	5.885e-27	120.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_1047514_1	1415166.NONO_c26800	7.498e-18	93.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria,4G4XI@85025|Nocardiaceae	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_1047863_0	1379270.AUXF01000003_gene3544	1.759e-110	368.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1ZSVF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
SRR25158527_k127_1047863_1	1238182.C882_2850	8.618e-19	96.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TSPY@28211|Alphaproteobacteria,2JRR5@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
SRR25158527_k127_1047863_2	1188256.BASI01000001_gene1284	2.356e-07	53.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,3FDAX@34008|Rhodovulum	28211|Alphaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158527_k127_1065116_0	671143.DAMO_2372	6.28e-138	454.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158527_k127_1075966_1	1144310.PMI07_005447	1.863e-50	192.0	COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1075966_0	1217720.ALOX01000032_gene200	4.871e-180	569.0	COG3391@1|root,COG3391@2|Bacteria,1R78P@1224|Proteobacteria,2U3BG@28211|Alphaproteobacteria,2JW9N@204441|Rhodospirillales	204441|Rhodospirillales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1076938_1	525904.Tter_0098	9.312e-44	170.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SRR25158527_k127_1076938_0	1120972.AUMH01000006_gene1898	9.252e-62	222.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	ligX	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
SRR25158527_k127_1077228_1	56780.SYN_00122	3.839e-73	251.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2MQY1@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158527_k127_1077228_0	330214.NIDE3443	5.624e-97	326.0	COG0111@1|root,COG4747@1|root,COG0111@2|Bacteria,COG4747@2|Bacteria,3J0DZ@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158527_k127_1080067_1	1232410.KI421412_gene411	9.925e-66	233.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158527_k127_1080067_0	1232410.KI421412_gene412	7.743e-68	239.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158527_k127_1088502_0	1122915.AUGY01000020_gene6479	3.232e-11	72.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1088502_1	1500897.JQNA01000002_gene4353	8.917e-07	60.0	COG0715@1|root,COG0715@2|Bacteria,1R3SJ@1224|Proteobacteria,2VMUC@28216|Betaproteobacteria,1K1MD@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Nitrate ABC transporter substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1090588_4	1027273.GZ77_08535	6.255e-07	53.0	COG3012@1|root,COG3012@2|Bacteria,1N1DD@1224|Proteobacteria,1S8TK@1236|Gammaproteobacteria,1XM2G@135619|Oceanospirillales	135619|Oceanospirillales	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SRR25158527_k127_1090588_3	1122915.AUGY01000118_gene6541	6.992e-19	98.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1090588_0	1382356.JQMP01000003_gene1487	2.423e-107	364.0	COG0624@1|root,COG0624@2|Bacteria,2GBDE@200795|Chloroflexi,27YXE@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158527_k127_1090588_1	867903.ThesuDRAFT_01637	2.916e-49	181.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,3WCK4@538999|Clostridiales incertae sedis	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
SRR25158527_k127_1090588_2	468059.AUHA01000004_gene2163	9.478e-28	117.0	COG0745@1|root,COG0784@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4251@2|Bacteria,4NFBM@976|Bacteroidetes,1INN9@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158527_k127_109312_0	1380394.JADL01000023_gene64	3.891e-42	156.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria,2JW4C@204441|Rhodospirillales	204441|Rhodospirillales	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158527_k127_109312_1	525897.Dbac_2170	4.93e-09	62.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,42VD3@68525|delta/epsilon subdivisions,2WRQJ@28221|Deltaproteobacteria,2MDDZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
SRR25158527_k127_109312_2	1122915.AUGY01000020_gene6479	2.627e-07	59.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1096632_0	338966.Ppro_2304	2.364e-115	379.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,43TP6@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158527_k127_1096632_3	398767.Glov_1872	3.716e-39	149.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,43UVT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158527_k127_1096632_4	1304880.JAGB01000001_gene523	2.502e-19	88.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158527_k127_1096632_2	525897.Dbac_2996	2.108e-51	186.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,42RHA@68525|delta/epsilon subdivisions,2WNQW@28221|Deltaproteobacteria,2M933@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158527_k127_1096632_1	292459.STH2558	3.186e-63	222.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SRR25158527_k127_1098988_1	566461.SSFG_06908	2.858e-22	98.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158527_k127_1098988_0	1380355.JNIJ01000031_gene3513	1.44e-94	320.0	COG2141@1|root,COG2141@2|Bacteria,1QGWA@1224|Proteobacteria,2UNBA@28211|Alphaproteobacteria,3K5C8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158527_k127_1099225_0	1231391.AMZF01000019_gene2027	9.013e-69	243.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158527_k127_1099225_1	1122915.AUGY01000020_gene6479	4.177e-15	83.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1101335_0	644282.Deba_0431	8.035e-134	440.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SRR25158527_k127_1103501_1	439235.Dalk_1881	1.039e-75	266.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R092@1224|Proteobacteria,43CRV@68525|delta/epsilon subdivisions,2X7ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158527_k127_1103501_0	246194.CHY_1808	3.593e-203	642.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42F6I@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_1103501_2	1121405.dsmv_1057	5.834e-05	50.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,2MITG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	4-hydroxybenzoate polyprenyltransferase	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158527_k127_1108581_1	1118054.CAGW01000075_gene3261	4.589e-09	64.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1108581_0	113395.AXAI01000002_gene5235	1.754e-56	208.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_1110254_0	941449.dsx2_0089	3.44e-16	89.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2X2GQ@28221|Deltaproteobacteria,2MC2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158527_k127_1110254_1	399795.CtesDRAFT_PD5001	2.376e-14	82.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,4ABX0@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SRR25158527_k127_1110254_2	1406840.Q763_00890	0.0009133	46.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2NS9J@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
SRR25158527_k127_111323_1	1347369.CCAD010000044_gene1027	6.252e-08	58.0	COG0494@1|root,COG0494@2|Bacteria,1TYS7@1239|Firmicutes,4I7XB@91061|Bacilli,1ZFQA@1386|Bacillus	91061|Bacilli	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158527_k127_111323_0	395495.Lcho_0045	9.024e-139	450.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
SRR25158527_k127_1113246_3	321332.CYB_2278	2.048e-13	71.0	COG4243@1|root,COG4243@2|Bacteria,1FZWT@1117|Cyanobacteria,1GYP5@1129|Synechococcus	1117|Cyanobacteria	CO	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SRR25158527_k127_1113246_5	1423724.BAMM01000004_gene661	2.281e-06	53.0	COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae	91061|Bacilli	P	Rhodanese-like protein	yqhL	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158527_k127_1113246_4	1455608.JDTH01000002_gene839	4.99e-07	52.0	COG0607@1|root,arCOG02021@2157|Archaea,2XW44@28890|Euryarchaeota,23S0R@183963|Halobacteria	183963|Halobacteria	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158527_k127_1113246_0	768671.ThimaDRAFT_4681	4.607e-94	313.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1WXBT@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
SRR25158527_k127_1113246_1	575540.Isop_2743	1.164e-42	168.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158527_k127_1113246_2	324602.Caur_3409	6.011e-28	130.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158527_k127_1114262_0	247490.KSU1_D0387	3.049e-194	618.0	COG0499@1|root,COG0499@2|Bacteria,2IXKQ@203682|Planctomycetes	203682|Planctomycetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158527_k127_1114262_1	338966.Ppro_0044	1.134e-141	455.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158527_k127_1118645_0	1254432.SCE1572_28970	1.351e-99	329.0	COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,438B8@68525|delta/epsilon subdivisions,2X1TZ@28221|Deltaproteobacteria,2YWF2@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N
SRR25158527_k127_1118645_3	1532558.JL39_06905	4.231e-21	106.0	COG1840@1|root,COG1840@2|Bacteria,1PGNI@1224|Proteobacteria,2V7J9@28211|Alphaproteobacteria,4B9P8@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11
SRR25158527_k127_1118645_1	105425.BBPL01000045_gene3219	1.242e-84	298.0	COG1032@1|root,COG1032@2|Bacteria,2GZU1@201174|Actinobacteria,2NI0T@228398|Streptacidiphilus	201174|Actinobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1118645_2	670487.Ocepr_0065	1.206e-37	149.0	COG4122@1|root,COG4122@2|Bacteria,1WKHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SRR25158527_k127_1121111_0	338966.Ppro_0966	1.374e-62	227.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,43UI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158527_k127_1121111_1	1121405.dsmv_2734	2.979e-24	105.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42VQ6@68525|delta/epsilon subdivisions,2WRTU@28221|Deltaproteobacteria,2MKPU@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158527_k127_1121111_2	868864.Dester_0239	1.284e-17	86.0	COG1550@1|root,COG1550@2|Bacteria,2G47V@200783|Aquificae	200783|Aquificae	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158527_k127_112855_0	56107.Cylst_1620	1.899e-136	457.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
SRR25158527_k127_1132915_4	1123508.JH636441_gene3410	7.034e-06	51.0	COG5550@1|root,COG5550@2|Bacteria,2J4CZ@203682|Planctomycetes	203682|Planctomycetes	O	TIGRFAM clan AA aspartic protease, AF_0612 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1132915_1	1122915.AUGY01000020_gene6479	1.735e-14	85.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1132915_2	68170.KL590490_gene1015	4.058e-11	72.0	COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria,4E4EM@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,Glyoxalase
SRR25158527_k127_1132915_3	266264.Rmet_5214	1.761e-06	58.0	COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2W22E@28216|Betaproteobacteria,1K74B@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_1132915_0	748247.AZKH_2194	2.232e-24	102.0	COG1032@1|root,COG1032@2|Bacteria,1PK5W@1224|Proteobacteria,2VJIN@28216|Betaproteobacteria,2KVTD@206389|Rhodocyclales	206389|Rhodocyclales	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158527_k127_1134582_0	671143.DAMO_0981	7.399e-221	691.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158527_k127_1134582_1	1189612.A33Q_4105	0.0005502	47.0	COG0589@1|root,COG0589@2|Bacteria,4NER9@976|Bacteroidetes,47PF0@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_1136752_1	443152.MDG893_15467	1.23e-43	173.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1136752_0	1500257.JQNM01000014_gene2939	1.465e-49	189.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,2UI7P@28211|Alphaproteobacteria,4BMG3@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1138558_1	1379270.AUXF01000004_gene3094	7.18e-28	123.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158527_k127_1138558_0	1122947.FR7_0239	4.047e-92	319.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes	1239|Firmicutes	E	Beta-eliminating lyase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
SRR25158527_k127_1138558_2	204536.SULAZ_1583	1.017e-24	114.0	COG1324@1|root,COG1324@2|Bacteria,2G58A@200783|Aquificae	200783|Aquificae	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158527_k127_1139082_1	1131814.JAFO01000001_gene3472	2.014e-32	132.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,3F1N4@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_1139082_0	1173028.ANKO01000116_gene5725	1.863e-47	185.0	COG4447@1|root,COG4447@2|Bacteria,1GAGV@1117|Cyanobacteria,1HF4J@1150|Oscillatoriales	1117|Cyanobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158527_k127_1142013_2	649747.HMPREF0083_03843	5.405e-96	323.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,26UE9@186822|Paenibacillaceae	91061|Bacilli	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158527_k127_1142013_1	1184267.A11Q_2005	2.214e-103	345.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2MT5D@213481|Bdellovibrionales,2WQU9@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158527_k127_1142013_0	1267535.KB906767_gene2712	4.152e-107	355.0	COG0583@1|root,COG0583@2|Bacteria,3Y34A@57723|Acidobacteria,2JKZ0@204432|Acidobacteriia	204432|Acidobacteriia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158527_k127_1142013_3	288000.BBta_7802	5.906e-62	221.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,3JVXA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158527_k127_1148074_1	1232410.KI421421_gene3688	5.877e-57	207.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRR25158527_k127_1148074_0	706587.Desti_1112	2.871e-104	344.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2MQ9P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158527_k127_1148512_0	526227.Mesil_1876	5.583e-102	343.0	COG0167@1|root,COG0167@2|Bacteria,1WI2W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158527_k127_1148512_1	357808.RoseRS_0825	7.399e-34	137.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi,377EI@32061|Chloroflexia	32061|Chloroflexia	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158527_k127_1153582_0	867903.ThesuDRAFT_01092	7.899e-74	264.0	COG0277@1|root,COG0277@2|Bacteria,1V135@1239|Firmicutes,24BZN@186801|Clostridia	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158527_k127_1153582_2	1182590.BN5_03552	3.565e-24	113.0	COG0697@1|root,COG0697@2|Bacteria,1R6SK@1224|Proteobacteria	1224|Proteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_1153582_1	1379698.RBG1_1C00001G1850	1.453e-43	164.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158527_k127_1154794_0	690585.JNNU01000009_gene534	2.414e-22	110.0	COG1840@1|root,COG1840@2|Bacteria,1PGNJ@1224|Proteobacteria,2V7JA@28211|Alphaproteobacteria,4BDDZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158527_k127_1161670_1	426716.JOAJ01000006_gene5141	1.872e-29	123.0	COG4638@1|root,COG4638@2|Bacteria,2GP4B@201174|Actinobacteria,4FWYI@85025|Nocardiaceae	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	hcaE_2	-	1.14.12.19	ko:K05708,ko:K14748	ko00360,ko00642,ko01100,ko01120,ko01220,map00360,map00642,map01100,map01120,map01220	M00545	R05440,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158527_k127_1161670_0	1415166.NONO_c29050	2.636e-45	170.0	COG5517@1|root,COG5517@2|Bacteria,2I8EV@201174|Actinobacteria,4G2C0@85025|Nocardiaceae	201174|Actinobacteria	Q	Ring hydroxylating beta subunit	bphE	-	-	ko:K14749	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05440	RC00098	br01602,ko00000,ko00001,ko01000	-	-	-	Ring_hydroxyl_B
SRR25158527_k127_1161670_2	743719.PaelaDRAFT_3384	3.097e-18	90.0	COG0346@1|root,COG0346@2|Bacteria,1UYR9@1239|Firmicutes,4IG96@91061|Bacilli,2700C@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158527_k127_1165284_0	448385.sce4660	8.515e-62	226.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2Z3JZ@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_1165284_2	1132836.RCCGE510_04897	1.108e-25	118.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,4BBDJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_1165284_1	1460634.JCM19037_1983	2.186e-54	203.0	COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli	91061|Bacilli	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	4.1.1.45,4.1.1.52	ko:K03392,ko:K22213	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR25158527_k127_1170692_1	1192034.CAP_2018	4.078e-53	200.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_1170692_0	1267534.KB906759_gene1729	1.865e-113	371.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	2|Bacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158527_k127_1173271_2	1230476.C207_05009	5.974e-18	93.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_1173271_0	502025.Hoch_0434	9.429e-73	259.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria	1224|Proteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158527_k127_1173271_1	1382356.JQMP01000001_gene834	1.889e-21	106.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1173335_1	671143.DAMO_0988	8.489e-25	109.0	COG1499@1|root,COG1499@2|Bacteria,2NS26@2323|unclassified Bacteria	2|Bacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
SRR25158527_k127_1173335_0	671143.DAMO_0975	8.398e-250	786.0	COG0465@1|root,COG0465@2|Bacteria,2NP22@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158527_k127_1177549_2	933262.AXAM01000027_gene2082	1.749e-05	48.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
SRR25158527_k127_1177549_1	1122915.AUGY01000118_gene6536	4.245e-17	93.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1177549_0	686340.Metal_4036	2.559e-17	85.0	2E4RC@1|root,32ZJW@2|Bacteria,1N8RU@1224|Proteobacteria,1SCQJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1179227_2	1042375.AFPL01000038_gene1506	4.02e-07	61.0	COG4521@1|root,COG4521@2|Bacteria,1MVH2@1224|Proteobacteria,1RRRT@1236|Gammaproteobacteria,469MW@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K15551	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	NMT1
SRR25158527_k127_1179227_0	767817.Desgi_2321	1.917e-20	101.0	COG0778@1|root,COG0778@2|Bacteria,1V31X@1239|Firmicutes,24GWX@186801|Clostridia,264WA@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158527_k127_1179227_1	1123023.JIAI01000006_gene33	3.59e-18	92.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4E4J0@85010|Pseudonocardiales	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_1185478_4	857293.CAAU_1986	5.624e-09	61.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,36F11@31979|Clostridiaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SRR25158527_k127_1185478_0	443143.GM18_4521	8.813e-100	346.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SRR25158527_k127_1185478_1	411464.DESPIG_02421	4.324e-24	106.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,42VNC@68525|delta/epsilon subdivisions,2WRIM@28221|Deltaproteobacteria,2MD5H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158527_k127_1185478_2	443143.GM18_4523	4.754e-18	88.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,43VN0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158527_k127_1185478_3	309799.DICTH_1849	2.618e-10	61.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158527_k127_1192858_0	1121468.AUBR01000028_gene1511	3.221e-112	385.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,42FXS@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158527_k127_1193784_3	378806.STAUR_3029	3.359e-06	57.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_1193784_1	287986.DV20_41745	3.924e-18	89.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	3-HAO,Cupin_2
SRR25158527_k127_1193784_0	331869.BAL199_17958	2.712e-38	146.0	2DS7S@1|root,33EWX@2|Bacteria,1NDGE@1224|Proteobacteria,2UH4Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1193784_2	1227266.HMPREF1551_01516	2.101e-07	55.0	COG3945@1|root,COG3945@2|Bacteria,4PNEF@976|Bacteroidetes,1IK4B@117743|Flavobacteriia	976|Bacteroidetes	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158527_k127_1198732_1	269799.Gmet_3260	1.983e-111	366.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,43U60@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158527_k127_1198732_2	395494.Galf_2212	1.731e-26	111.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
SRR25158527_k127_1198732_3	580332.Slit_1979	1.745e-13	75.0	COG5393@1|root,COG5393@2|Bacteria,1PUGQ@1224|Proteobacteria,2WATV@28216|Betaproteobacteria,44WJB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
SRR25158527_k127_1198732_0	1120999.JONM01000009_gene294	8.433e-137	457.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VI60@28216|Betaproteobacteria,2KQM5@206351|Neisseriales	206351|Neisseriales	M	Psort location Periplasmic, score 9.44	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158527_k127_1199070_1	765420.OSCT_1703	2.409e-62	232.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158527_k127_1199070_0	1304885.AUEY01000026_gene3553	2.434e-181	585.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MHT0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158527_k127_1199070_2	330214.NIDE3327	6.379e-36	139.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158527_k127_1206630_1	983917.RGE_46940	1.754e-28	120.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158527_k127_1206630_0	1123371.ATXH01000010_gene751	3.327e-178	572.0	COG0272@1|root,COG0272@2|Bacteria,2GGUH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SRR25158527_k127_1209101_0	1123371.ATXH01000008_gene229	1.546e-70	246.0	COG1159@1|root,COG1159@2|Bacteria,2GGXK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158527_k127_1209101_1	1459636.NTE_02734	1.39e-14	81.0	arCOG11830@1|root,arCOG11830@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1211152_0	1125863.JAFN01000001_gene886	3.033e-90	304.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158527_k127_1211152_1	1173021.ALWA01000037_gene3499	7.747e-47	175.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_1213211_1	234621.RER_54220	9.651e-39	158.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4FZ2D@85025|Nocardiaceae	201174|Actinobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	catB	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158527_k127_1213211_0	1499967.BAYZ01000103_gene3741	4.507e-104	345.0	COG1032@1|root,COG1032@2|Bacteria,2NQ35@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
SRR25158527_k127_1217161_5	1502851.FG93_03217	6.021e-05	50.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TWR2@28211|Alphaproteobacteria,3JVDD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_1217161_2	44454.NF84_12460	4.566e-40	163.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1217161_1	1123023.JIAI01000001_gene6358	1.705e-45	176.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria,4E06G@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_1217161_3	203124.Tery_2073	1.265e-29	124.0	COG0662@1|root,COG0662@2|Bacteria,1GDUY@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_1217161_4	203124.Tery_2073	1.541e-24	108.0	COG0662@1|root,COG0662@2|Bacteria,1GDUY@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_1217161_0	639283.Snov_4076	8.721e-77	271.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,3F0K5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	gci	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158527_k127_1218178_0	439235.Dalk_3324	6.246e-100	333.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2MID1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM PhoH family protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158527_k127_1218178_2	1047013.AQSP01000098_gene2561	2.839e-43	162.0	COG0432@1|root,COG0432@2|Bacteria,2NPR7@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158527_k127_1218178_1	338963.Pcar_2408	4.651e-95	321.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,43THC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158527_k127_1230152_3	484022.Fphi_0609	3.617e-33	132.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,45ZZ1@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
SRR25158527_k127_1230152_0	509191.AEDB02000103_gene3760	1.659e-114	378.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WH1H@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
SRR25158527_k127_1230152_1	1121405.dsmv_3222	2.978e-37	141.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MKMM@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SRR25158527_k127_1230152_2	1131269.AQVV01000019_gene778	1.703e-33	131.0	COG0261@1|root,COG0261@2|Bacteria	2|Bacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SRR25158527_k127_1239989_0	1382306.JNIM01000001_gene1934	2.396e-56	208.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1239989_1	1122915.AUGY01000118_gene6536	1.799e-18	94.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1242412_0	1331060.RLDS_06070	1.065e-76	267.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria	1224|Proteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	4.1.1.68	ko:K05921	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04134,R04380	RC01085,RC02669	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
SRR25158527_k127_1242412_1	359.CN09_19970	1.08e-09	63.0	COG0346@1|root,COG0346@2|Bacteria,1PJ3N@1224|Proteobacteria,2UF0Z@28211|Alphaproteobacteria,4BEYH@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_1243833_4	330214.NIDE2040	8.603e-26	107.0	COG0147@1|root,COG0147@2|Bacteria,3J0FG@40117|Nitrospirae	40117|Nitrospirae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158527_k127_1243833_1	1408254.T458_25155	8.634e-80	273.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85	ko:K01664	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	iYO844.BSU00750	GATase
SRR25158527_k127_1243833_3	690850.Desaf_2821	1.147e-26	113.0	COG0726@1|root,COG0726@2|Bacteria,1RH3I@1224|Proteobacteria,42T75@68525|delta/epsilon subdivisions,2WPC1@28221|Deltaproteobacteria,2MEZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Archaea-specific editing domain of threonyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-Thr_ED
SRR25158527_k127_1243833_5	265729.GS18_0211975	4.097e-05	53.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus	91061|Bacilli	M	COG3103 SH3 domain protein	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
SRR25158527_k127_1243833_0	1120936.KB907221_gene2112	1.735e-87	299.0	COG2159@1|root,COG2159@2|Bacteria,2GN9D@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR25158527_k127_1243833_2	697281.Mahau_0349	3.007e-45	182.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,42F15@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3,Sugar_tr
SRR25158527_k127_1246995_0	404380.Gbem_0264	9.401e-62	217.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42RS2@68525|delta/epsilon subdivisions,2X9GK@28221|Deltaproteobacteria,43W2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158527_k127_1246995_2	1110502.TMO_0012	4.503e-33	141.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1246995_1	1123377.AUIV01000021_gene2543	6.691e-44	165.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1X4PF@135614|Xanthomonadales	135614|Xanthomonadales	I	fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158527_k127_1247225_1	877455.Metbo_0422	1.516e-55	207.0	COG0111@1|root,COG2150@1|root,arCOG01754@2157|Archaea,arCOG02316@2157|Archaea,2XU9V@28890|Euryarchaeota,23NQM@183925|Methanobacteria	183925|Methanobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158527_k127_1247225_2	262316.MAP_1627	1.465e-49	189.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1247225_3	880073.Calab_2669	8.178e-44	175.0	COG0438@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,2NPQ4@2323|unclassified Bacteria	2|Bacteria	J	Glycosyltransferase like family 2	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_23
SRR25158527_k127_1247225_4	240292.Ava_0849	3.404e-29	129.0	COG1216@1|root,COG1216@2|Bacteria,1G2ZC@1117|Cyanobacteria,1HJ8R@1161|Nostocales	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158527_k127_1247225_0	1120949.KB903314_gene302	5.086e-129	431.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1,SBP_bac_6
SRR25158527_k127_1250794_2	1500306.JQLA01000003_gene4503	2.561e-16	93.0	2E560@1|root,32ZYT@2|Bacteria,1RD6P@1224|Proteobacteria,2UJ9J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1250794_0	1121448.DGI_1413	2.621e-76	278.0	29D6U@1|root,3004T@2|Bacteria,1R9I1@1224|Proteobacteria,42T9I@68525|delta/epsilon subdivisions,2WPXB@28221|Deltaproteobacteria,2MADE@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1250794_1	388051.AUFE01000017_gene5758	3.98e-47	171.0	28M5B@1|root,2ZAJ4@2|Bacteria,1R7Y9@1224|Proteobacteria,2VSMK@28216|Betaproteobacteria,1K5H6@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1260013_1	1100720.ALKN01000052_gene507	2.278e-48	189.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_1260013_2	446471.Xcel_2528	5.502e-20	103.0	COG0477@1|root,COG2814@2|Bacteria,2H0CW@201174|Actinobacteria,4F5ZJ@85017|Promicromonosporaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_1260013_0	640081.Dsui_3444	2.88e-51	184.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KU9M@206389|Rhodocyclales	206389|Rhodocyclales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SRR25158527_k127_1268573_1	1123073.KB899243_gene722	2.213e-139	454.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,1RMY2@1236|Gammaproteobacteria,1XDBK@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_1268573_0	1123073.KB899243_gene722	4.688e-144	469.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,1RMY2@1236|Gammaproteobacteria,1XDBK@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_1268573_2	1123073.KB899243_gene722	2.669e-127	420.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,1RMY2@1236|Gammaproteobacteria,1XDBK@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_1271790_1	1120949.KB903314_gene304	2.667e-59	220.0	2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1271790_0	487521.OCU_39710	3.478e-150	489.0	COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae	201174|Actinobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_1278527_0	237368.SCABRO_00651	6.497e-204	647.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877,ko:K07501	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,DNA_pol_B_exo2,RNase_H_2
SRR25158527_k127_1278527_1	330214.NIDE3580	5.831e-34	143.0	COG1028@1|root,COG1028@2|Bacteria	330214.NIDE3580|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR25158527_k127_128408_0	338966.Ppro_0674	1.322e-252	789.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43UIG@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158527_k127_1287844_4	172088.AUGA01000045_gene6765	8.798e-18	87.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,3JQSY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158527_k127_1287844_2	386415.NT01CX_2251	3.267e-43	170.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,36ED0@31979|Clostridiaceae	186801|Clostridia	S	tigr00255	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SRR25158527_k127_1287844_0	335543.Sfum_3634	9.069e-77	268.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,2MQGF@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
SRR25158527_k127_1287844_3	429009.Adeg_0321	8.104e-41	165.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,42FGD@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158527_k127_1287844_1	247490.KSU1_D0287	1.237e-74	258.0	COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158527_k127_1288769_0	215803.DB30_0441	2.1e-118	392.0	COG1063@1|root,COG1063@2|Bacteria,1NXSN@1224|Proteobacteria,438FZ@68525|delta/epsilon subdivisions,2X3QX@28221|Deltaproteobacteria,2YWVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glucose dehydrogenase C-terminus	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
SRR25158527_k127_1288769_1	864702.OsccyDRAFT_4593	7.878e-90	302.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria,1H9H5@1150|Oscillatoriales	1117|Cyanobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SRR25158527_k127_129596_2	1121028.ARQE01000007_gene3803	5.611e-11	63.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2PKBA@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
SRR25158527_k127_129596_0	94624.Bpet2245	5.472e-55	205.0	COG3181@1|root,COG3181@2|Bacteria,1P88K@1224|Proteobacteria,2VJJP@28216|Betaproteobacteria,3T1V0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_129596_1	224719.Abm4_0698	1.191e-12	70.0	COG4032@1|root,arCOG01613@2157|Archaea,2XYBY@28890|Euryarchaeota,23PJE@183925|Methanobacteria	183925|Methanobacteria	S	sulfopyruvate decarboxylase, alpha subunit	comD	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158527_k127_1296520_1	68170.KL590490_gene1015	1.424e-12	76.0	COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria,4E4EM@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,Glyoxalase
SRR25158527_k127_1296520_0	1382306.JNIM01000001_gene2427	1.053e-52	197.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_1297689_1	671143.DAMO_0983	1.385e-21	100.0	COG0589@1|root,COG0589@2|Bacteria,2NPUM@2323|unclassified Bacteria	2|Bacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_1297689_0	479434.Sthe_2667	3.174e-38	155.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_1298810_5	1122915.AUGY01000118_gene6526	2.662e-06	57.0	COG0715@1|root,COG0715@2|Bacteria,1UZYY@1239|Firmicutes,4HE24@91061|Bacilli,26RHH@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_1298810_0	1547437.LL06_00335	1.853e-60	221.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,43IZ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	4.1.1.55	ko:K04102	ko00624,ko01100,ko01120,map00624,map01100,map01120	M00623	R01635,R05375	RC00390	ko00000,ko00001,ko00002,ko01000	-	-	-	NMT1
SRR25158527_k127_1298810_2	545693.BMQ_3698	1.327e-46	179.0	COG0329@1|root,COG0329@2|Bacteria,1UXBS@1239|Firmicutes,4HTGW@91061|Bacilli,1ZCYS@1386|Bacillus	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_1298810_4	935840.JAEQ01000004_gene646	3.358e-17	93.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1298810_1	1279017.AQYJ01000029_gene3723	3.47e-49	179.0	COG1917@1|root,COG1917@2|Bacteria,1R5IE@1224|Proteobacteria,1S3I4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_1298810_3	246196.MSMEI_5063	1.132e-32	137.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,2334B@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158527_k127_1299660_2	1172185.KB911523_gene3597	5.062e-13	70.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FV60@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158527_k127_1299660_0	1120960.ATXG01000005_gene2514	2.299e-102	346.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FKZV@85023|Microbacteriaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158527_k127_1299660_1	1382356.JQMP01000001_gene814	6.121e-42	164.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_1301173_1	748247.AZKH_1931	2.635e-51	189.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,2KW5T@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_1301173_0	257310.BB0681	1.048e-116	388.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2W02V@28216|Betaproteobacteria	28216|Betaproteobacteria	L	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158527_k127_1301724_0	765912.Thimo_2582	3.506e-142	462.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1WWF4@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SRR25158527_k127_1301724_2	296591.Bpro_5254	1.907e-32	130.0	COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,2VV15@28216|Betaproteobacteria,4AJFM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158527_k127_1301724_1	1231190.NA8A_14544	3.757e-97	331.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria,43KJI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1304172_1	63737.Npun_R2053	1.359e-53	198.0	COG1073@1|root,COG1073@2|Bacteria,1GGWP@1117|Cyanobacteria,1HTF4@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100
SRR25158527_k127_1304172_0	96561.Dole_2215	1.199e-100	341.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2MHXQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158527_k127_1304597_0	794903.OPIT5_05950	3.39e-99	332.0	COG0343@1|root,COG0343@2|Bacteria,46U5K@74201|Verrucomicrobia,3K919@414999|Opitutae	414999|Opitutae	J	S-adenosyl-L-methionine-dependent methyltransferase	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	Methyltransf_30,TGT
SRR25158527_k127_1304597_1	187272.Mlg_1829	3.442e-71	250.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,1WW3F@135613|Chromatiales	135613|Chromatiales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
SRR25158527_k127_1304597_2	472759.Nhal_2693	3.207e-36	141.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1WYI6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the HSP15 family	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
SRR25158527_k127_1304597_3	314256.OG2516_16354	6.674e-08	57.0	COG3181@1|root,COG3181@2|Bacteria,1PF42@1224|Proteobacteria,2V8PZ@28211|Alphaproteobacteria,2PFVC@252301|Oceanicola	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1306941_0	398767.Glov_0704	3.683e-270	855.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158527_k127_1306941_1	933262.AXAM01000010_gene1371	9.007e-37	141.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2MHR7@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158527_k127_1307696_1	1110502.TMO_0012	1.894e-54	205.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1307696_0	1128912.GMES_2046	4.959e-111	362.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,468S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	SGL
SRR25158527_k127_1319510_1	330214.NIDE0277	9.934e-09	68.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
SRR25158527_k127_1319510_0	1157490.EL26_23155	4.063e-164	525.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,277YV@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158527_k127_1331607_1	1430440.MGMSRv2_2287	2.412e-51	189.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SRR25158527_k127_1331607_0	479434.Sthe_1533	2.731e-79	274.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,27YWI@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158527_k127_1337824_2	404589.Anae109_3810	4.921e-59	209.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria	1224|Proteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
SRR25158527_k127_1337824_0	243231.GSU1705	1.66e-99	331.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,43S2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SRR25158527_k127_1337824_1	498761.HM1_0668	1.033e-96	325.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158527_k127_1337824_3	717773.Thicy_1027	7.156e-08	57.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,461RE@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
SRR25158527_k127_1348199_2	269799.Gmet_2198	1.269e-40	164.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_1348199_0	1499680.CCFE01000023_gene2581	2.908e-51	197.0	COG1960@1|root,COG1960@2|Bacteria,1UX6T@1239|Firmicutes,4IJKC@91061|Bacilli,1ZM73@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_1348199_1	1123023.JIAI01000010_gene8642	1.204e-48	179.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudL	GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158527_k127_1348199_3	94624.Bpet2434	1.557e-09	60.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNP8@28216|Betaproteobacteria,3T1Y0@506|Alcaligenaceae	28216|Betaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4976,Sulfatase
SRR25158527_k127_1351884_1	443144.GM21_0005	4.242e-115	374.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,43T5S@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158527_k127_1351884_0	2342.SOPEG_4127	2.875e-140	458.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158527_k127_1360339_1	290512.Paes_0121	1.66e-44	166.0	COG0743@1|root,COG0743@2|Bacteria,1FD70@1090|Chlorobi	1090|Chlorobi	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158527_k127_1360339_0	1121405.dsmv_2170	4.467e-106	356.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2MIEV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SRR25158527_k127_1360339_2	1499967.BAYZ01000084_gene3996	3.676e-33	138.0	COG1214@1|root,COG1214@2|Bacteria,2NPK8@2323|unclassified Bacteria	2|Bacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158527_k127_1363864_0	1502851.FG93_02509	5.97e-234	738.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,3JX83@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_1363864_1	1429916.X566_14890	3.809e-146	467.0	COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,3K3FV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158527_k127_1363864_3	1323663.AROI01000008_gene2627	1.079e-13	79.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria	1224|Proteobacteria	C	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center	rubA	GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Rubredoxin
SRR25158527_k127_1363864_2	227882.SAV_5962	3.688e-22	104.0	COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,Glyoxalase
SRR25158527_k127_1368265_0	404380.Gbem_0485	3.658e-162	529.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158527_k127_1368265_2	671143.DAMO_2306	3.484e-07	56.0	2DT1T@1|root,33IAD@2|Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	FtsL
SRR25158527_k127_1368265_1	309801.trd_0056	3.299e-57	205.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,27XI5@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	-	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158527_k127_1372030_0	164757.Mjls_0083	3.984e-91	306.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,2341D@1762|Mycobacteriaceae	201174|Actinobacteria	S	haloacid dehalogenase	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
SRR25158527_k127_1372030_1	1123023.JIAI01000004_gene7873	1.77e-62	229.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_1372030_2	1267005.KB911255_gene2873	7.349e-42	160.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2UBYB@28211|Alphaproteobacteria,3N76W@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	TspO/MBR family	tspO	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
SRR25158527_k127_137748_3	404380.Gbem_3102	7.707e-46	168.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43U6J@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158527_k127_137748_1	398767.Glov_1748	3.594e-57	205.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158527_k127_137748_0	264732.Moth_0915	2.397e-112	376.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158527_k127_137748_2	338966.Ppro_1595	1.254e-54	199.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,43UMU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158527_k127_1384711_1	481448.Minf_0142	2.496e-49	184.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_1384711_0	452637.Oter_3914	2.498e-103	351.0	COG0531@1|root,COG0531@2|Bacteria,46SPF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158527_k127_1389811_2	1499967.BAYZ01000095_gene4127	1.53e-24	104.0	COG0809@1|root,COG0809@2|Bacteria,2NNWD@2323|unclassified Bacteria	2|Bacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SRR25158527_k127_1389811_1	269799.Gmet_0852	3.353e-138	449.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43TNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SRR25158527_k127_1389811_3	1121448.DGI_2738	6.392e-24	104.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MCSM@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158527_k127_1389811_0	933262.AXAM01000020_gene23	3.179e-153	501.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2MHS8@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158527_k127_1389811_4	1121396.KB893083_gene439	1.304e-14	80.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MI34@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158527_k127_1390339_2	877424.ATWC01000007_gene267	6.595e-34	137.0	COG5663@1|root,COG5663@2|Bacteria,1UZJ5@1239|Firmicutes,24BE6@186801|Clostridia,27J1A@186928|unclassified Lachnospiraceae	186801|Clostridia	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
SRR25158527_k127_1390339_0	304371.MCP_0033	3.991e-62	220.0	COG2094@1|root,arCOG04295@2157|Archaea,2Y0AE@28890|Euryarchaeota,2NB07@224756|Methanomicrobia	224756|Methanomicrobia	L	alkylbase DNA N-glycosylase activity	mpg	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158527_k127_1390339_1	670292.JH26_22525	8.83e-43	160.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2U67J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
SRR25158527_k127_1390339_3	62928.azo2391	2.593e-06	55.0	COG0715@1|root,COG0715@2|Bacteria,1NF3S@1224|Proteobacteria,2WEG1@28216|Betaproteobacteria,2KVYA@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_1399112_2	933262.AXAM01000034_gene1562	6.676e-32	132.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2MKHV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158527_k127_1399112_1	404589.Anae109_0456	4.958e-162	516.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YTSX@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158527_k127_1399112_3	518766.Rmar_0661	1.514e-25	111.0	COG2137@1|root,COG2137@2|Bacteria,4PERV@976|Bacteroidetes,1FJHK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158527_k127_1399112_0	1232410.KI421428_gene1168	1.318e-230	731.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,43THC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158527_k127_1402250_0	935840.JAEQ01000004_gene646	1.8e-22	104.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1402250_1	1123504.JQKD01000007_gene3481	2.16e-11	67.0	COG3181@1|root,COG3181@2|Bacteria,1R61G@1224|Proteobacteria,2VIUX@28216|Betaproteobacteria,4AH34@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1404175_1	1131462.DCF50_p1839	0.0001261	51.0	COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,24MK8@186801|Clostridia,2624R@186807|Peptococcaceae	186801|Clostridia	S	PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
SRR25158527_k127_1404175_0	491915.Aflv_1772	1.609e-52	196.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,21W76@150247|Anoxybacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
SRR25158527_k127_1415801_0	204669.Acid345_1270	7.074e-161	511.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158527_k127_1415801_3	1142394.PSMK_14070	8.987e-27	124.0	COG3011@1|root,COG3011@2|Bacteria,2J432@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
SRR25158527_k127_1415801_1	204669.Acid345_1270	2.729e-66	237.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158527_k127_1415801_2	234267.Acid_7336	7.372e-60	212.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158527_k127_1417858_1	316067.Geob_2398	1.635e-33	133.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,43T7S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SRR25158527_k127_1417858_2	1320556.AVBP01000030_gene171	4.082e-10	66.0	COG0346@1|root,COG0346@2|Bacteria,1RIN8@1224|Proteobacteria,2U9WM@28211|Alphaproteobacteria,43K76@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_1417858_0	296591.Bpro_3467	1.021e-65	230.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,4ABP9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Luciferase family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_1419308_1	1268068.PG5_42060	1.315e-43	173.0	COG0726@1|root,COG3195@1|root,COG0726@2|Bacteria,COG3195@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158527_k127_1419308_0	349521.HCH_01653	1.977e-126	409.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,1RPVI@1236|Gammaproteobacteria,1XHJX@135619|Oceanospirillales	135619|Oceanospirillales	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158527_k127_1430638_1	1267535.KB906767_gene3817	1.742e-46	170.0	COG5611@1|root,COG5611@2|Bacteria	2|Bacteria	S	PIN domain	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158527_k127_1430638_0	1168059.KB899087_gene1279	2.593e-118	394.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3F11J@335928|Xanthobacteraceae	28211|Alphaproteobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
SRR25158527_k127_1430638_2	42256.RradSPS_2996	3.523e-09	57.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria	84995|Rubrobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158527_k127_1431848_1	1120973.AQXL01000134_gene1653	1.965e-34	134.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,2782V@186823|Alicyclobacillaceae	91061|Bacilli	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SRR25158527_k127_1431848_0	76114.p2A120	2.645e-140	455.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_1437333_1	710685.MycrhN_4733	6.868e-07	51.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1437333_0	266779.Meso_2924	5.421e-171	553.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,43GZZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_1438250_0	62928.azo3052	2.671e-222	700.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,2KY7V@206389|Rhodocyclales	206389|Rhodocyclales	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_1438250_1	76114.ebA5303	7.159e-175	556.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VIK5@28216|Betaproteobacteria,2KY62@206389|Rhodocyclales	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158527_k127_1439907_0	1267534.KB906754_gene2822	0.0	1105.0	COG2010@1|root,COG2010@2|Bacteria,3Y31J@57723|Acidobacteria,2JKC9@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1439907_1	748247.AZKH_4256	4.877e-12	66.0	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2VIIC@28216|Betaproteobacteria,2KY5V@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1445487_1	234267.Acid_0302	1.486e-76	262.0	COG0602@1|root,COG0602@2|Bacteria,3Y2UA@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SRR25158527_k127_1445487_0	1121033.AUCF01000003_gene3032	7.853e-209	677.0	COG0744@1|root,COG0768@1|root,COG0744@2|Bacteria,COG0768@2|Bacteria,1NRPB@1224|Proteobacteria,2U4T0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
SRR25158527_k127_1450336_1	269799.Gmet_2360	7.342e-127	411.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,43SYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158527_k127_1450336_2	335543.Sfum_3743	6.432e-113	383.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SRR25158527_k127_1450336_3	56780.SYN_00922	2.003e-69	244.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2MQF7@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SRR25158527_k127_1450336_0	316067.Geob_2097	9.005e-134	454.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,43UEF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158527_k127_1451673_0	797299.HALLA_02515	2.62e-113	372.0	COG4948@1|root,arCOG01168@2157|Archaea,2XUAS@28890|Euryarchaeota,23SVB@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158527_k127_1451673_1	1347392.CCEZ01000007_gene2096	3.533e-44	173.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,36DUP@31979|Clostridiaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mbl	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158527_k127_1453112_0	693661.Arcve_1526	4.291e-48	178.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,246MG@183980|Archaeoglobi	183980|Archaeoglobi	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158527_k127_1453112_1	1121360.AUAQ01000015_gene1935	2.518e-14	83.0	COG0420@1|root,COG0420@2|Bacteria,2HQKD@201174|Actinobacteria,22KH3@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA repair exonuclease	sbcD	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158527_k127_1457200_1	292459.STH2788	3.184e-05	54.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
SRR25158527_k127_1457200_0	671143.DAMO_1573	3.806e-112	374.0	COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria	2|Bacteria	E	Metallopeptidase family M24	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
SRR25158527_k127_1459799_1	555079.Toce_1070	9.61e-14	71.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,42GJ8@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158527_k127_1459799_2	207559.Dde_0991	3.895e-05	53.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158527_k127_1459799_0	338966.Ppro_2242	3.412e-139	452.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,43TE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158527_k127_1465003_1	883.DvMF_1150	7.311e-07	57.0	COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,42WA7@68525|delta/epsilon subdivisions,2WRWX@28221|Deltaproteobacteria,2MCC2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158527_k127_1465003_0	130081.XP_005709258.1	2.151e-122	402.0	COG1804@1|root,KOG3957@2759|Eukaryota	2759|Eukaryota	C	alpha-methylacyl-CoA racemase activity	SUGCT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008410,GO:0016740,GO:0016782,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047369	2.8.3.13	ko:K18703	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158527_k127_1472871_0	330214.NIDE0997	1.478e-250	783.0	COG0028@1|root,COG0028@2|Bacteria,3J0D6@40117|Nitrospirae	40117|Nitrospirae	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_1472871_1	330214.NIDE0998	1.807e-65	227.0	COG0440@1|root,COG0440@2|Bacteria,3J0K8@40117|Nitrospirae	40117|Nitrospirae	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158527_k127_1476587_1	909663.KI867151_gene3132	4.058e-66	236.0	COG0774@1|root,COG2204@1|root,COG0774@2|Bacteria,COG2204@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,2MRFZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	MT	UDP-3-O-acyl N-acetylglycosamine deacetylase	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
SRR25158527_k127_1476587_0	1232410.KI421415_gene3124	2.869e-170	553.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158527_k127_1481634_0	443152.MDG893_15295	1.294e-61	225.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1481634_1	443152.MDG893_15467	3.289e-53	201.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1484564_1	290397.Adeh_3160	6.193e-15	77.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,42ZSX@68525|delta/epsilon subdivisions,2WV17@28221|Deltaproteobacteria,2YZ2N@29|Myxococcales	28221|Deltaproteobacteria	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158527_k127_1484564_0	96561.Dole_0769	1.374e-26	125.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,42Q28@68525|delta/epsilon subdivisions,2X5UF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158527_k127_1484709_9	1205680.CAKO01000002_gene3085	6.54e-10	62.0	2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2UVTT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
SRR25158527_k127_1484709_4	314271.RB2654_02824	2.057e-91	312.0	COG1073@1|root,COG1073@2|Bacteria,1N5CG@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0255 family	frsA	GO:0003674,GO:0003824,GO:0005575,GO:0006109,GO:0006629,GO:0008150,GO:0008152,GO:0009894,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0019222,GO:0043470,GO:0044238,GO:0050789,GO:0065007,GO:0071704,GO:0080090	-	ko:K11750	-	-	-	-	ko00000,ko01000	-	-	-	DUF1100
SRR25158527_k127_1484709_3	156889.Mmc1_3712	1.158e-112	370.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158527_k127_1484709_2	404589.Anae109_2522	2.546e-124	408.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158527_k127_1484709_5	986075.CathTA2_3037	1.391e-45	169.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158527_k127_1484709_1	1121918.ARWE01000001_gene1474	2.345e-134	441.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158527_k127_1484709_0	671143.DAMO_0707	1.591e-191	610.0	COG1003@1|root,COG1003@2|Bacteria,2NNSG@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
SRR25158527_k127_1484709_8	411684.HPDFL43_07949	6.087e-10	70.0	COG0810@1|root,COG0810@2|Bacteria,1RESZ@1224|Proteobacteria,2U7Y2@28211|Alphaproteobacteria,43RD1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
SRR25158527_k127_1484709_7	690850.Desaf_2994	1.232e-13	73.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MD43@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158527_k127_1484709_10	338963.Pcar_2546	1.854e-06	59.0	2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CF4@68525|delta/epsilon subdivisions,2WP3G@28221|Deltaproteobacteria,43SKD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4
SRR25158527_k127_1484709_6	1254432.SCE1572_42100	1.082e-40	157.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158527_k127_1496607_1	335543.Sfum_4019	3.197e-22	97.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MSIG@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158527_k127_1496607_0	1120972.AUMH01000002_gene2761	3.003e-69	251.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_1502519_3	269799.Gmet_0777	6.339e-36	142.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43TNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SRR25158527_k127_1502519_4	316067.Geob_2318	3.176e-20	94.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,42WU5@68525|delta/epsilon subdivisions,2WRRS@28221|Deltaproteobacteria,43SRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
SRR25158527_k127_1502519_0	1131269.AQVV01000002_gene1185	1.137e-139	451.0	COG2255@1|root,COG2255@2|Bacteria	2|Bacteria	L	four-way junction helicase activity	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158527_k127_1502519_1	1499967.BAYZ01000068_gene1975	1.894e-52	192.0	COG0632@1|root,COG0632@2|Bacteria,2NPR6@2323|unclassified Bacteria	2|Bacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158527_k127_1502519_2	243231.GSU1075	1.382e-42	162.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,43US0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158527_k127_1502519_5	574087.Acear_0700	2.511e-11	64.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WAD4@53433|Halanaerobiales	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158527_k127_1503698_3	1162668.LFE_0905	1.549e-23	100.0	COG0361@1|root,COG0361@2|Bacteria,3J0QB@40117|Nitrospirae	40117|Nitrospirae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158527_k127_1503698_1	644282.Deba_2916	8.244e-97	323.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158527_k127_1503698_2	1125863.JAFN01000001_gene3315	1.756e-80	274.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158527_k127_1503698_0	335543.Sfum_1575	2.116e-190	602.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MQSV@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158527_k127_1503698_4	926567.TheveDRAFT_0599	9.016e-05	44.0	COG0200@1|root,COG0200@2|Bacteria,3TB6A@508458|Synergistetes	508458|Synergistetes	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158527_k127_1517743_2	204669.Acid345_1270	1.094e-21	94.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SRR25158527_k127_1517743_1	1532557.JL37_25740	6.845e-25	116.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VPVX@28216|Betaproteobacteria,3T3CX@506|Alcaligenaceae	28216|Betaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
SRR25158527_k127_1517743_0	1234664.AMRO01000077_gene3333	1.69e-42	168.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1WG3J@129337|Geobacillus	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR25158527_k127_1523291_1	582515.KR51_00008590	6.457e-49	185.0	COG0589@1|root,COG0589@2|Bacteria,1GDD7@1117|Cyanobacteria	1117|Cyanobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_1523291_0	522306.CAP2UW1_0145	1.354e-76	265.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,PTS_EIIC
SRR25158527_k127_1525111_2	1173028.ANKO01000227_gene1237	3.35e-12	67.0	2CCSR@1|root,32RWC@2|Bacteria,1GA04@1117|Cyanobacteria,1HDA0@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158527_k127_1525111_3	179408.Osc7112_4977	2.805e-10	62.0	2CCSR@1|root,32RWC@2|Bacteria,1GA04@1117|Cyanobacteria,1HDA0@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158527_k127_1525111_1	378806.STAUR_2326	9.702e-55	220.0	COG0642@1|root,COG3852@1|root,COG0642@2|Bacteria,COG3852@2|Bacteria,1NXDJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07716,ko:K20974	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,CHASE3,HATPase_c,HisKA,PAS_7,Response_reg
SRR25158527_k127_1525111_0	1040989.AWZU01000065_gene6524	1.993e-141	484.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWPQ@28211|Alphaproteobacteria,3K6KM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
SRR25158527_k127_1525111_4	1380355.JNIJ01000048_gene33	7.344e-05	45.0	2AHTU@1|root,3186F@2|Bacteria,1NN1Q@1224|Proteobacteria,2UTGK@28211|Alphaproteobacteria,3K4KG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158527_k127_1529443_1	443152.MDG893_15295	1.351e-26	122.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1529443_0	443152.MDG893_15467	8.516e-50	192.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1532394_0	335543.Sfum_0290	8.432e-96	330.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MSIQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transglycosylase	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158527_k127_1532394_1	335543.Sfum_0291	2.474e-05	54.0	COG0457@1|root,COG0457@2|Bacteria	335543.Sfum_0291|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1539839_0	485913.Krac_10287	3.743e-159	515.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158527_k127_1548204_0	398767.Glov_2079	3.883e-190	600.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,43TR2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158527_k127_1548204_1	1232410.KI421413_gene595	1.809e-165	529.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SRR25158527_k127_1548204_2	273075.Ta0575	8.004e-70	260.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,241J0@183967|Thermoplasmata	183967|Thermoplasmata	F	aspartate carbamoyltransferase activity	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158527_k127_1548204_3	1032480.MLP_36870	4.437e-43	164.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,4DQ8W@85009|Propionibacteriales	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SRR25158527_k127_1550818_0	1122221.JHVI01000021_gene2431	4.182e-67	235.0	COG2935@1|root,COG2935@2|Bacteria	2|Bacteria	O	arginyltransferase activity	ate	GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
SRR25158527_k127_1550818_1	443144.GM21_3206	1.239e-31	128.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,43SA4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283,ko:K03609	-	-	-	-	ko00000,ko02035,ko02044,ko03036,ko04812	-	-	-	CbiA,FHA,T2SSE
SRR25158527_k127_1551552_1	1267534.KB906756_gene370	1.107e-53	196.0	COG0443@1|root,COG0443@2|Bacteria,3Y3QN@57723|Acidobacteria,2JIM6@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
SRR25158527_k127_1551552_0	234267.Acid_5615	1.676e-65	230.0	COG0443@1|root,COG0443@2|Bacteria,3Y3QN@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
SRR25158527_k127_1551552_2	765177.Desmu_0449	7.771e-11	73.0	COG1524@1|root,COG3379@1|root,arCOG01377@2157|Archaea,arCOG01378@2157|Archaea,2XPVN@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158527_k127_1553368_1	593117.TGAM_1014	6.069e-55	197.0	COG3839@1|root,arCOG00175@2157|Archaea,2Y7MB@28890|Euryarchaeota	28890|Euryarchaeota	E	PFAM ABC transporter	-	-	3.6.3.29,3.6.3.30	ko:K02010,ko:K02017,ko:K02062,ko:K10112,ko:K10199,ko:K17314	ko02010,map02010	M00189,M00190,M00191,M00194,M00196,M00197,M00200,M00201,M00203,M00206,M00207,M00491,M00602,M00604,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.13,3.A.1.1.14,3.A.1.1.15,3.A.1.10,3.A.1.19,3.A.1.8	-	-	ABC_tran,TOBE_2
SRR25158527_k127_1553368_0	395494.Galf_2724	1.433e-101	334.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VKX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SRR25158527_k127_1560097_0	215803.DB30_2329	2.868e-70	252.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1NR2V@1224|Proteobacteria,42YIK@68525|delta/epsilon subdivisions,2WUNG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MV	MacB-like periplasmic core domain	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158527_k127_1560097_1	316274.Haur_2605	5.905e-69	240.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi,375II@32061|Chloroflexia	32061|Chloroflexia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158527_k127_1560097_2	1173025.GEI7407_0832	1.129e-17	87.0	COG1547@1|root,COG1547@2|Bacteria,1G7QG@1117|Cyanobacteria,1HBGH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158527_k127_1562749_2	751944.HALDL1_03155	1.267e-23	112.0	COG0697@1|root,arCOG00272@2157|Archaea,2XVSM@28890|Euryarchaeota,23S7J@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_1562749_1	1260251.SPISAL_02225	9.893e-25	107.0	2EJUZ@1|root,33DJM@2|Bacteria,1NIYD@1224|Proteobacteria,1SGV4@1236|Gammaproteobacteria,1WZJR@135613|Chromatiales	135613|Chromatiales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SRR25158527_k127_1562749_0	221288.JH992901_gene1253	1.006e-42	159.0	COG3805@1|root,COG3805@2|Bacteria,1G7MF@1117|Cyanobacteria,1JM07@1189|Stigonemataceae	1117|Cyanobacteria	Q	Dopa 4,5-dioxygenase family	-	-	-	ko:K10253	-	-	-	-	ko00000,ko01000	-	-	-	DOPA_dioxygen
SRR25158527_k127_1562802_1	1231391.AMZF01000068_gene2180	7.94e-44	171.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_1562802_0	269799.Gmet_2198	9.282e-50	192.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_1569312_1	1131269.AQVV01000082_gene26	0.0001006	46.0	COG0457@1|root,COG4262@1|root,COG0457@2|Bacteria,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
SRR25158527_k127_1569312_0	76114.p2A133	1.407e-248	777.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2W317@28216|Betaproteobacteria	28216|Betaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_1569841_0	742733.HMPREF9469_02956	7.761e-35	142.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,21XDT@1506553|Lachnoclostridium	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_157394_4	635013.TherJR_2806	2.485e-12	68.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,24QZ4@186801|Clostridia,2636A@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158527_k127_157394_2	1121439.dsat_0843	3.709e-43	170.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,2MAZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158527_k127_157394_3	485915.Dret_1160	5.554e-42	168.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,42QS0@68525|delta/epsilon subdivisions,2WMU6@28221|Deltaproteobacteria,2M8XP@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM Type II secretion system F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
SRR25158527_k127_157394_0	443143.GM18_2435	1.015e-177	567.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,43SA4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283,ko:K03609	-	-	-	-	ko00000,ko02035,ko02044,ko03036,ko04812	-	-	-	CbiA,FHA,T2SSE
SRR25158527_k127_157394_1	1304872.JAGC01000009_gene382	2.112e-43	171.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,42QEH@68525|delta/epsilon subdivisions,2WKVC@28221|Deltaproteobacteria,2MAS2@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ,ParA,Response_reg
SRR25158527_k127_1583593_2	1499968.TCA2_2333	0.0001991	51.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,4HEW0@91061|Bacilli,26RDX@186822|Paenibacillaceae	91061|Bacilli	M	Myristoyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_1583593_0	272134.KB731324_gene1337	3.411e-59	210.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SRR25158527_k127_1583593_1	1038860.AXAP01000097_gene5007	1.356e-36	151.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_1593867_0	1469607.KK073769_gene6211	1.716e-27	117.0	COG1249@1|root,COG1249@2|Bacteria,1G0W0@1117|Cyanobacteria,1HM2V@1161|Nostocales	1117|Cyanobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158527_k127_1593867_2	89187.ISM_12135	3.93e-08	58.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,46P4Y@74030|Roseovarius	28211|Alphaproteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	gor	GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158527_k127_1593867_1	247490.KSU1_D0617	1.599e-20	100.0	COG1266@1|root,COG1266@2|Bacteria,2J329@203682|Planctomycetes	203682|Planctomycetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SRR25158527_k127_1606052_0	335543.Sfum_2433	1.302e-185	593.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42RS1@68525|delta/epsilon subdivisions,2WNR1@28221|Deltaproteobacteria,2MQVG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
SRR25158527_k127_1609406_2	1121405.dsmv_1965	0.0004358	48.0	COG0589@1|root,COG0589@2|Bacteria,1PEB7@1224|Proteobacteria,42XVC@68525|delta/epsilon subdivisions,2WSNF@28221|Deltaproteobacteria,2MMDT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_1609406_1	371042.NG99_26640	2.291e-19	94.0	2DT3P@1|root,33IIT@2|Bacteria,1NMA5@1224|Proteobacteria,1SJ4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1609406_0	443152.MDG893_15295	1.108e-51	195.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1619980_3	1121405.dsmv_3218	4.539e-31	129.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2MKMJ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SRR25158527_k127_1619980_2	338963.Pcar_2578	8.704e-59	211.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,43TRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cytidylyltransferase-like	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
SRR25158527_k127_1619980_0	1123371.ATXH01000038_gene1353	1.987e-167	535.0	COG0014@1|root,COG0014@2|Bacteria,2GH1U@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158527_k127_1619980_1	338966.Ppro_2953	9.745e-71	246.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,43SXM@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
SRR25158527_k127_1620387_0	1131730.BAVI_09631	9.399e-96	332.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,1ZB8V@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_1623646_1	1411123.JQNH01000001_gene950	2.703e-14	84.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1623646_0	1231391.AMZF01000046_gene961	8.785e-38	155.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_1625390_2	1232410.KI421420_gene3180	1.725e-15	78.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,43SSF@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	mttA/Hcf106 family	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158527_k127_1625390_1	933262.AXAM01000033_gene1627	1.089e-91	312.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MJGP@213118|Desulfobacterales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SRR25158527_k127_1625390_0	269799.Gmet_1603	9.984e-97	322.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,43TSR@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158527_k127_1626169_1	443152.MDG893_15295	2.667e-06	54.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1626169_0	443152.MDG893_15285	3.038e-81	280.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctA
SRR25158527_k127_1626623_2	742159.HMPREF0004_4940	3.887e-08	65.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,3T1MD@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_1626623_1	62928.azo2391	1.49e-10	72.0	COG0715@1|root,COG0715@2|Bacteria,1NF3S@1224|Proteobacteria,2WEG1@28216|Betaproteobacteria,2KVYA@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_1626623_0	1122915.AUGY01000020_gene6479	3.496e-21	106.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1630482_1	1173020.Cha6605_1540	2.962e-38	146.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_1630482_0	379066.GAU_2917	1.505e-156	507.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
SRR25158527_k127_1630482_5	1095769.CAHF01000016_gene7	0.0002844	47.0	COG5002@1|root,COG5002@2|Bacteria,1RI2X@1224|Proteobacteria,2WGVH@28216|Betaproteobacteria,474ZU@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS
SRR25158527_k127_1630482_4	751945.Theos_1638	8.591e-10	62.0	2A200@1|root,30Q9V@2|Bacteria,1WN7Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1630482_3	751945.Theos_1639	3.683e-34	135.0	COG4113@1|root,COG4113@2|Bacteria,1WKRQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158527_k127_1630482_2	477184.KYC_23728	3.593e-34	136.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2VNPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158527_k127_1631471_1	1265502.KB905929_gene2216	1.96e-26	114.0	COG2453@1|root,COG2453@2|Bacteria,1NDVQ@1224|Proteobacteria,2VWYX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
SRR25158527_k127_1631471_0	1382359.JIAL01000001_gene558	1.738e-123	402.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158527_k127_1637828_3	420324.KI912006_gene8704	5.058e-11	66.0	COG0346@1|root,COG0346@2|Bacteria,1PJ3N@1224|Proteobacteria,2UF0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_1637828_0	1120972.AUMH01000002_gene2761	2.595e-99	338.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_1637828_2	1538295.JY96_14600	8.82e-43	162.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1637828_1	551275.KB899544_gene1323	1.048e-82	286.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,43WH3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158527_k127_163956_1	1123229.AUBC01000005_gene591	1.353e-38	164.0	COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,2TXW7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_163956_0	1380394.JADL01000003_gene4948	4.039e-77	264.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VEZC@28211|Alphaproteobacteria,2JU3P@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
SRR25158527_k127_1655862_0	404589.Anae109_4094	3.281e-203	646.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
SRR25158527_k127_1656318_0	1521187.JPIM01000006_gene1761	1.704e-25	106.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,374VN@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158527_k127_1656318_2	717231.Flexsi_1870	0.0001007	50.0	28VW0@1|root,2ZHXF@2|Bacteria,2GG5K@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1656318_1	945713.IALB_0263	5.36e-07	60.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07710,ko:K10942	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
SRR25158527_k127_1656516_1	1267535.KB906767_gene1406	1.425e-10	65.0	COG2076@1|root,COG2076@2|Bacteria	2|Bacteria	P	Multidrug Resistance protein	-	-	-	ko:K03297,ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	EamA,Multi_Drug_Res
SRR25158527_k127_1666772_0	1123229.AUBC01000013_gene2548	1.355e-24	117.0	COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2UH3P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1673403_2	1415780.JPOG01000001_gene2668	7.709e-21	106.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1X503@135614|Xanthomonadales	135614|Xanthomonadales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
SRR25158527_k127_1673403_1	177437.HRM2_18550	4.1e-88	302.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,2MHYF@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SRR25158527_k127_1673403_0	1123267.JONN01000001_gene2459	4.481e-159	514.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,2K0Q1@204457|Sphingomonadales	204457|Sphingomonadales	G	phosphomannomutase	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158527_k127_1677023_1	706587.Desti_3788	7.372e-61	212.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2MQWK@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PhoH-like protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158527_k127_1677023_0	1167006.UWK_03129	1.851e-126	415.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MN5K@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158527_k127_1677023_2	243090.RB10283	1.979e-06	49.0	COG0071@1|root,COG0071@2|Bacteria,2J0K5@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158527_k127_1680961_1	547559.Nmag_1268	5.02e-17	88.0	arCOG08113@1|root,arCOG08113@2157|Archaea,2XV1B@28890|Euryarchaeota,23TAX@183963|Halobacteria	183963|Halobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158527_k127_1680961_0	349161.Dred_1504	7.717e-71	256.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,263RX@186807|Peptococcaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_1683007_4	266117.Rxyl_2314	7.998e-21	93.0	2DBV6@1|root,32TY6@2|Bacteria	2|Bacteria	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
SRR25158527_k127_1683007_1	266117.Rxyl_2315	1.496e-80	273.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Nitrile hydratase alpha	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
SRR25158527_k127_1683007_5	1217715.F994_03048	2.444e-19	94.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,3NIEF@468|Moraxellaceae	1236|Gammaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0006457,GO:0008150,GO:0009987	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158527_k127_1683007_2	1231391.AMZF01000003_gene3115	5.016e-71	248.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2W95G@28216|Betaproteobacteria,3T7RQ@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158527_k127_1683007_0	234267.Acid_0345	1.605e-99	332.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158527_k127_1683007_3	349521.HCH_04968	1.58e-48	178.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,1XJCP@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126,SHOCT
SRR25158527_k127_1687291_0	1047013.AQSP01000140_gene2513	1.305e-89	306.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158527_k127_1687291_1	1123376.AUIU01000016_gene231	6.241e-57	210.0	COG5002@1|root,COG5002@2|Bacteria,3J10G@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158527_k127_1687891_0	243274.THEMA_03280	2.232e-147	481.0	COG0205@1|root,COG0205@2|Bacteria,2GC8H@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158527_k127_1687891_1	264732.Moth_0262	3.206e-143	461.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158527_k127_1687891_2	635013.TherJR_0656	8.142e-23	102.0	COG3448@1|root,COG3448@2|Bacteria,1UJ4A@1239|Firmicutes,25EVN@186801|Clostridia,267DA@186807|Peptococcaceae	186801|Clostridia	T	pfam cbs	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158527_k127_1687975_1	583355.Caka_1445	4.482e-42	162.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158527_k127_1687975_0	1122194.AUHU01000002_gene2483	6.834e-295	922.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,464M6@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158527_k127_1687975_2	502025.Hoch_5003	2.031e-33	131.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2YVP9@29|Myxococcales	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SRR25158527_k127_1691475_1	883.DvMF_1588	6.841e-55	198.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,42TI5@68525|delta/epsilon subdivisions,2WQR8@28221|Deltaproteobacteria,2MG9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158527_k127_1691475_0	246969.TAM4_600	1.43e-108	364.0	COG3839@1|root,arCOG00177@2157|Archaea,2XTU1@28890|Euryarchaeota	28890|Euryarchaeota	E	COG3842 ABC-type spermidine putrescine transport systems, ATPase components	-	-	3.6.3.29,3.6.3.30,3.6.3.55	ko:K02010,ko:K02017,ko:K15497	ko02010,map02010	M00189,M00190,M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.6.5,3.A.1.8	-	-	ABC_tran,TOBE,TOBE_2
SRR25158527_k127_1691475_2	1379698.RBG1_1C00001G0893	1.824e-36	145.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
SRR25158527_k127_1703919_0	504472.Slin_2683	9.677e-82	286.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47K06@768503|Cytophagia	976|Bacteroidetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158527_k127_1703919_1	563192.HMPREF0179_00538	1.045e-41	168.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,43BCY@68525|delta/epsilon subdivisions,2X6RW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_1703919_2	1499680.CCFE01000021_gene2043	2.258e-12	77.0	COG2159@1|root,COG2159@2|Bacteria,1UZAH@1239|Firmicutes,4HA5S@91061|Bacilli,1ZFUI@1386|Bacillus	91061|Bacilli	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_1705270_1	1131730.BAVI_08341	2.503e-16	90.0	COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,1ZIFT@1386|Bacillus	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1705270_0	1449063.JMLS01000027_gene61	7.379e-23	109.0	COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1719114_1	1089553.Tph_c11730	8.274e-28	114.0	COG0714@1|root,COG0714@2|Bacteria,1TYE4@1239|Firmicutes,249V6@186801|Clostridia,42ETG@68295|Thermoanaerobacterales	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158527_k127_1719114_0	1202768.JROF01000016_gene1335	4.527e-39	156.0	COG3332@1|root,arCOG06429@2157|Archaea,2XU65@28890|Euryarchaeota,23UCP@183963|Halobacteria	183963|Halobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
SRR25158527_k127_1719114_2	1380356.JNIK01000011_gene1927	1.114e-11	70.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4ESRH@85013|Frankiales	201174|Actinobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158527_k127_1720332_0	4530.OS02T0700500-01	4.287e-24	107.0	COG0531@1|root,KOG1287@2759|Eukaryota,37JZU@33090|Viridiplantae,3GAHX@35493|Streptophyta,3KTWW@4447|Liliopsida,3I2IV@38820|Poales	35493|Streptophyta	E	Amino acid permease	PUT1	GO:0002376,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0006928,GO:0006950,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015203,GO:0015291,GO:0015297,GO:0015318,GO:0015695,GO:0015696,GO:0015711,GO:0015807,GO:0015839,GO:0015846,GO:0015849,GO:0016020,GO:0016021,GO:0016043,GO:0016477,GO:0019752,GO:0022607,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0040011,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0048870,GO:0050896,GO:0050900,GO:0051179,GO:0051234,GO:0051674,GO:0055085,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0098656,GO:1901564,GO:1902047,GO:1902475,GO:1903825,GO:1905039	-	ko:K11584	ko03015,ko04071,ko04113,ko04114,ko04151,ko04152,ko04261,ko04728,ko05165,map03015,map04071,map04113,map04114,map04151,map04152,map04261,map04728,map05165	-	-	-	ko00000,ko00001,ko01009,ko03036	-	-	-	AA_permease_2
SRR25158527_k127_1720332_1	1236541.BALL01000003_gene686	1.341e-19	99.0	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,1SCJF@1236|Gammaproteobacteria,2QCNK@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158527_k127_1720332_2	497964.CfE428DRAFT_2465	1.871e-14	77.0	291HJ@1|root,2ZP44@2|Bacteria,46WS5@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1725128_0	483219.LILAB_22395	2.719e-310	967.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158527_k127_1725128_1	398767.Glov_2445	5.805e-16	84.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158527_k127_1728986_3	671143.DAMO_1263	1.643e-54	192.0	COG0780@1|root,COG0780@2|Bacteria,2NPZV@2323|unclassified Bacteria	2|Bacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
SRR25158527_k127_1728986_0	443144.GM21_1409	1.283e-174	558.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SRR25158527_k127_1728986_2	706587.Desti_4505	9.625e-58	210.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,42U27@68525|delta/epsilon subdivisions,2WR2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SRR25158527_k127_1728986_4	1033743.CAES01000099_gene2606	9.184e-47	177.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,26UCZ@186822|Paenibacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SRR25158527_k127_1728986_1	443144.GM21_1405	5.529e-108	357.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_1736945_0	1254432.SCE1572_13245	3.221e-291	922.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2X4FQ@28221|Deltaproteobacteria,2YYXH@29|Myxococcales	28221|Deltaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_23,PP-binding
SRR25158527_k127_1743398_0	485913.Krac_9791	1.267e-76	277.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1743661_2	1123274.KB899424_gene3004	0.000642	49.0	COG0457@1|root,COG0457@2|Bacteria,2J7SI@203691|Spirochaetes	203691|Spirochaetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_7,TPR_8
SRR25158527_k127_1743661_1	644966.Tmar_0255	2.673e-39	162.0	COG0730@1|root,COG0730@2|Bacteria,1TRIE@1239|Firmicutes	1239|Firmicutes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158527_k127_1743661_0	1123376.AUIU01000012_gene1409	1.538e-65	231.0	COG0382@1|root,COG0382@2|Bacteria,3J0TY@40117|Nitrospirae	40117|Nitrospirae	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158527_k127_174582_0	1121396.KB892935_gene3861	1.261e-53	205.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_1757431_1	1356854.N007_02415	1.16e-44	169.0	COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HI7T@91061|Bacilli	91061|Bacilli	K	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon	mntR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158527_k127_1757431_0	1158345.JNLL01000001_gene2000	4.05e-48	183.0	COG0589@1|root,COG0589@2|Bacteria,2G4YU@200783|Aquificae	200783|Aquificae	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_1772079_0	1038859.AXAU01000013_gene6516	9.787e-86	287.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,3JUT4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158527_k127_1772079_1	1037409.BJ6T_41080	1.141e-80	276.0	COG1131@1|root,COG1131@2|Bacteria,1NT51@1224|Proteobacteria,2UPEH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158527_k127_1772079_2	1254432.SCE1572_24535	2.442e-55	200.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SRR25158527_k127_1776259_0	671143.DAMO_1565	2.979e-258	807.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158527_k127_1787818_2	196490.AUEZ01000105_gene2948	1.637e-13	82.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_1787818_1	1122915.AUGY01000118_gene6541	5.701e-22	108.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1787818_0	314230.DSM3645_08892	2.943e-78	274.0	COG2141@1|root,COG2141@2|Bacteria,2J00I@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_1790493_3	1122919.KB905552_gene525	1.653e-05	53.0	COG1335@1|root,COG1335@2|Bacteria,1UZ1J@1239|Firmicutes,4HEGW@91061|Bacilli,26TKR@186822|Paenibacillaceae	91061|Bacilli	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158527_k127_1790493_2	573569.F7308_1473	8.711e-07	60.0	COG1073@1|root,COG1073@2|Bacteria,1RCSJ@1224|Proteobacteria,1S2PJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1790493_0	388401.RB2150_08919	2.418e-34	140.0	COG0625@1|root,COG0625@2|Bacteria,1MWUG@1224|Proteobacteria,2TTZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
SRR25158527_k127_1793074_2	1397666.RS24_01724	0.0001133	44.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,4BQ29@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158527_k127_1793074_1	1232410.KI421418_gene2372	2.097e-58	213.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,43SCU@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal RNA adenine dimethylases	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158527_k127_1793074_0	1121918.ARWE01000001_gene1565	9.304e-109	361.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,43S66@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Glycoprotease family	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158527_k127_1802507_0	398767.Glov_0364	2.21e-93	320.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158527_k127_1806640_0	215803.DB30_6646	5.659e-118	388.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2YTTG@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
SRR25158527_k127_1806640_2	1499967.BAYZ01000048_gene2681	7.735e-86	294.0	COG1116@1|root,COG1116@2|Bacteria,2NPDJ@2323|unclassified Bacteria	2|Bacteria	P	ATPases associated with a variety of cellular activities	MA20_28765	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158527_k127_1806640_5	1535287.JP74_08375	5.858e-28	126.0	COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2TSHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1806640_4	1416752.AYME01000017_gene1951	2.628e-55	204.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4FPFE@85023|Microbacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158527_k127_1806640_1	1192034.CAP_3447	7.864e-102	346.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,42RUS@68525|delta/epsilon subdivisions,2WNWT@28221|Deltaproteobacteria,2YWXA@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
SRR25158527_k127_1806640_6	1286631.X805_26000	7.305e-27	115.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1KM7X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
SRR25158527_k127_1806640_3	443152.MDG893_15040	1.594e-63	223.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria	1224|Proteobacteria	E	ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_1811043_1	326427.Cagg_2880	8.379e-15	74.0	COG0537@1|root,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi,377B8@32061|Chloroflexia	32061|Chloroflexia	FG	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
SRR25158527_k127_1811043_0	525904.Tter_1872	1.268e-165	532.0	COG1239@1|root,COG1239@2|Bacteria,2NQQG@2323|unclassified Bacteria	2|Bacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
SRR25158527_k127_1811438_1	1380390.JIAT01000009_gene1212	2.3e-152	497.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4CPPX@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10	ko:K00135,ko:K22445	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158527_k127_1811438_2	573413.Spirs_3457	2.058e-51	191.0	COG1028@1|root,COG1028@2|Bacteria,2J8GM@203691|Spirochaetes	203691|Spirochaetes	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158527_k127_1811438_0	330214.NIDE3448	5.337e-181	573.0	COG2805@1|root,COG2805@2|Bacteria,3J0YS@40117|Nitrospirae	40117|Nitrospirae	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SRR25158527_k127_1811438_3	247490.KSU1_C1110	2.215e-20	93.0	COG5008@1|root,COG5008@2|Bacteria,2J2NM@203682|Planctomycetes	203682|Planctomycetes	NU	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
SRR25158527_k127_1812158_0	1125973.JNLC01000018_gene2316	6.416e-107	363.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,3K00D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_1816200_2	671143.DAMO_2462	0.0004836	51.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
SRR25158527_k127_1816200_0	562970.Btus_2139	5.059e-174	556.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,277WY@186823|Alicyclobacillaceae	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158527_k127_1816200_1	266940.Krad_0422	1.176e-65	234.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158527_k127_1819198_1	485913.Krac_2148	4.184e-57	209.0	COG1028@1|root,COG1028@2|Bacteria,2G8CF@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158527_k127_1819198_0	1380394.JADL01000017_gene522	4.702e-113	376.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,2JPUP@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_1820951_3	1278073.MYSTI_04069	8.8e-28	118.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2YV06@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158527_k127_1820951_2	269799.Gmet_1958	2.112e-50	187.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,43US2@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SRR25158527_k127_1820951_0	429009.Adeg_1292	8.591e-70	246.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158527_k127_1820951_1	383372.Rcas_0318	4.838e-61	212.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi,376KE@32061|Chloroflexia	32061|Chloroflexia	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158527_k127_1821267_0	1231391.AMZF01000006_gene2823	2.274e-62	227.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2VMW1@28216|Betaproteobacteria,3T349@506|Alcaligenaceae	28216|Betaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	4.1.1.55	ko:K04102	ko00624,ko01100,ko01120,map00624,map01100,map01120	M00623	R01635,R05375	RC00390	ko00000,ko00001,ko00002,ko01000	-	-	-	NMT1
SRR25158527_k127_1821267_1	1463921.JODF01000054_gene69	1.166e-29	126.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158527_k127_182911_2	1205680.CAKO01000006_gene3183	7.168e-39	149.0	COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2TTSB@28211|Alphaproteobacteria,2JPQH@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158527_k127_182911_1	1410620.SHLA_34c000820	1.539e-86	306.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2TSZ0@28211|Alphaproteobacteria,4BCJN@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158527_k127_182911_0	1429916.X566_03175	7.772e-124	414.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,3JST2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158527_k127_183040_0	243231.GSU1607	6.75e-166	526.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43U6J@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158527_k127_183040_3	404380.Gbem_3103	3.277e-47	174.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2WP1V@28221|Deltaproteobacteria,43UNK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
SRR25158527_k127_183040_5	1408439.JHXW01000014_gene1753	6.428e-26	108.0	COG0236@1|root,COG0236@2|Bacteria,37AM1@32066|Fusobacteria	32066|Fusobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158527_k127_183040_2	484770.UFO1_2065	6.036e-81	276.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158527_k127_183040_1	1232410.KI421413_gene692	4.825e-110	366.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158527_k127_183040_4	1499967.BAYZ01000186_gene3963	4.435e-31	127.0	COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15	ko:K03621,ko:K21576,ko:K21577	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158527_k127_1832662_1	580327.Tthe_0568	5.78e-37	145.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,42F00@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SRR25158527_k127_1832662_0	316058.RPB_4416	1.132e-200	649.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158527_k127_1832662_2	690585.JNNU01000008_gene3736	1.04e-08	62.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,4B98I@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1834371_3	743719.PaelaDRAFT_0962	7.333e-11	74.0	COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1834371_2	994479.GL877879_gene5651	1.755e-74	262.0	COG3618@1|root,COG3618@2|Bacteria,2IB8W@201174|Actinobacteria,4ECU7@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_1834371_1	1242864.D187_000932	1.026e-99	345.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria	1224|Proteobacteria	G	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158527_k127_1834371_0	627192.SLG_07750	1.179e-129	418.0	COG2159@1|root,COG2159@2|Bacteria,1R7NS@1224|Proteobacteria,2UP6K@28211|Alphaproteobacteria,2KDHT@204457|Sphingomonadales	204457|Sphingomonadales	S	Amidohydrolase	-	-	-	ko:K15062	ko00627,ko01120,map00627,map01120	-	R09277	RC00757,RC02478	ko00000,ko00001	-	-	-	Amidohydro_2
SRR25158527_k127_1847159_2	1233950.IW22_14730	0.0002146	49.0	COG1917@1|root,COG3391@1|root,COG1917@2|Bacteria,COG3391@2|Bacteria,4NHWP@976|Bacteroidetes,1I0PC@117743|Flavobacteriia,3ZRC0@59732|Chryseobacterium	976|Bacteroidetes	S	Major royal jelly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
SRR25158527_k127_1847159_0	1118054.CAGW01000075_gene3261	1.468e-17	96.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1847159_1	1118054.CAGW01000075_gene3261	1.779e-14	85.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1849987_4	545276.KB898727_gene315	9.311e-32	130.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1WWBW@135613|Chromatiales	135613|Chromatiales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158527_k127_1849987_0	880072.Desac_0681	8.097e-221	691.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,2MQ9T@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158527_k127_1849987_1	1121405.dsmv_2177	1.2e-90	305.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2MJCG@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158527_k127_1849987_2	349161.Dred_1977	4.639e-81	274.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,260PI@186807|Peptococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158527_k127_1849987_3	1121448.DGI_3412	1.648e-40	155.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2M9TD@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158527_k127_1851093_0	861299.J421_0533	4.509e-29	124.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158527_k127_1851093_1	339860.Msp_0278	2.095e-26	115.0	COG4032@1|root,arCOG01613@2157|Archaea,2XYBY@28890|Euryarchaeota,23PJE@183925|Methanobacteria	183925|Methanobacteria	S	sulfopyruvate decarboxylase, alpha subunit	comD	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158527_k127_1851093_2	1007105.PT7_2285	2.747e-12	70.0	COG3181@1|root,COG3181@2|Bacteria,1P88K@1224|Proteobacteria,2VJJP@28216|Betaproteobacteria,3T1V0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1851094_2	269799.Gmet_1399	1.578e-11	70.0	COG4968@1|root,COG4968@2|Bacteria,1QXNR@1224|Proteobacteria,43C4N@68525|delta/epsilon subdivisions,2WRDZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	pilA-N	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
SRR25158527_k127_1851094_0	1120972.AUMH01000002_gene2761	2.171e-89	306.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_1851094_1	1120972.AUMH01000002_gene2762	8.621e-77	271.0	COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,4HAEM@91061|Bacilli	91061|Bacilli	E	ethanolamine utilization protein	eutA	-	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
SRR25158527_k127_1853887_1	1134413.ANNK01000127_gene2529	3.55e-96	323.0	COG0726@1|root,COG0726@2|Bacteria,1VA2Q@1239|Firmicutes,4HEX3@91061|Bacilli,1ZK98@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158527_k127_1853887_0	1144310.PMI07_006194	5.383e-111	368.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2TRSE@28211|Alphaproteobacteria,4BDNH@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158527_k127_1853934_3	313612.L8106_19726	8.162e-06	56.0	COG5424@1|root,COG5424@2|Bacteria,1G23M@1117|Cyanobacteria,1H8T4@1150|Oscillatoriales	1117|Cyanobacteria	H	Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158527_k127_1853934_0	1088721.NSU_2080	8.93e-13	72.0	COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2UK4T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158527_k127_1853934_2	1273125.Rrhod_3316	1.168e-06	60.0	COG0715@1|root,COG0715@2|Bacteria,2I171@201174|Actinobacteria,4G4RH@85025|Nocardiaceae	201174|Actinobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1853934_1	930945.SiRe_2499	2.606e-07	61.0	COG5424@1|root,arCOG06031@2157|Archaea,2XRWB@28889|Crenarchaeota	28889|Crenarchaeota	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4,zf-C2H2_9
SRR25158527_k127_1854016_0	1242864.D187_005641	7.781e-66	233.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,4305M@68525|delta/epsilon subdivisions,2WVCR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158527_k127_1854016_1	1333856.L686_16240	1.624e-38	152.0	COG1335@1|root,COG1335@2|Bacteria,1QU95@1224|Proteobacteria,1T2S7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158527_k127_1854016_2	443152.MDG893_15295	1.264e-24	109.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1857128_0	309801.trd_1809	3.543e-38	155.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_1860461_2	926549.KI421517_gene3468	6.334e-13	76.0	COG0457@1|root,COG0457@2|Bacteria,4NXQQ@976|Bacteroidetes,47T7B@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_1860461_1	391625.PPSIR1_04398	2.231e-30	124.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158527_k127_1860461_0	411464.DESPIG_02375	1.007e-121	396.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2M80I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158527_k127_1860718_3	1328313.DS2_07548	2.066e-08	61.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria,468F1@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158527_k127_1860718_2	502025.Hoch_2732	4.188e-47	176.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
SRR25158527_k127_1860718_1	234267.Acid_3676	1.103e-59	211.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria	57723|Acidobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158527_k127_1860718_0	344747.PM8797T_15421	2.595e-116	380.0	COG0334@1|root,COG0334@2|Bacteria,2IWWC@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158527_k127_1869506_0	1499967.BAYZ01000095_gene4241	1.569e-93	323.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	GATase1_like,VWA,VWA_2,VWA_3
SRR25158527_k127_1873483_0	1205680.CAKO01000002_gene2637	3.329e-126	417.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2JPAV@204441|Rhodospirillales	204441|Rhodospirillales	H	glutamate--cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
SRR25158527_k127_1873483_1	1267535.KB906767_gene4340	1.709e-119	392.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria,2JHZX@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158527_k127_1884985_4	671143.DAMO_2907	8.1e-68	240.0	COG3842@1|root,COG3842@2|Bacteria,2NPAF@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	potA	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158527_k127_1884985_1	977880.RALTA_A0747	1.181e-148	477.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1JZVS@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	fbpA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_1884985_0	977880.RALTA_A0749	5.277e-193	617.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,1K2SU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	transporter	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158527_k127_1884985_2	292415.Tbd_0723	1.793e-118	405.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,2VIUK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Iron permease FTR1	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,FTR1
SRR25158527_k127_1884985_3	944479.JQLX01000011_gene916	1.095e-75	256.0	COG2406@1|root,COG2406@2|Bacteria,1RE25@1224|Proteobacteria,42PJ1@68525|delta/epsilon subdivisions,2WNTY@28221|Deltaproteobacteria,2M6IM@213113|Desulfurellales	28221|Deltaproteobacteria	S	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158527_k127_1899206_0	1458357.BG58_25755	3.707e-06	57.0	COG4521@1|root,COG4521@2|Bacteria,1MVH2@1224|Proteobacteria,2VINJ@28216|Betaproteobacteria,1JZVK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	taurine ABC transporter	tauA	-	-	ko:K15551	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	NMT1,NMT1_2
SRR25158527_k127_190141_1	1458357.BG58_16545	8.182e-13	74.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,1K855@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_190141_0	694427.Palpr_2664	7.193e-161	517.0	COG2060@1|root,COG2060@2|Bacteria,4NF2G@976|Bacteroidetes,2FP4S@200643|Bacteroidia,22WF2@171551|Porphyromonadaceae	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRR25158527_k127_1906858_2	754035.Mesau_01519	9.344e-07	54.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1906858_1	1237149.C900_03139	5.343e-29	123.0	COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes,47RE3@768503|Cytophagia	976|Bacteroidetes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
SRR25158527_k127_1906858_0	562970.Btus_1633	1.105e-53	202.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_191055_2	265072.Mfla_2628	0.0001691	49.0	COG0715@1|root,COG2202@1|root,COG5001@1|root,COG0715@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KMBP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,NMT1,PAS_3,PAS_9
SRR25158527_k127_191055_1	1123386.AUIW01000001_gene268	4.749e-16	89.0	COG0715@1|root,COG0715@2|Bacteria,1WJPE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_191055_0	880073.Calab_1106	2.854e-45	168.0	COG2080@1|root,COG2080@2|Bacteria,2NPPX@2323|unclassified Bacteria	2|Bacteria	C	PFAM 2Fe-2S -binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2,TAT_signal
SRR25158527_k127_1911761_0	767817.Desgi_0645	2.236e-66	240.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,2607C@186807|Peptococcaceae	186801|Clostridia	C	PFAM CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158527_k127_1911761_1	1121877.JQKF01000008_gene624	8.624e-29	121.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CNIB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158527_k127_1912711_0	404589.Anae109_1579	1.22e-110	361.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158527_k127_1912711_1	935948.KE386494_gene670	4.082e-08	64.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,24EN3@186801|Clostridia,42GFD@68295|Thermoanaerobacterales	186801|Clostridia	P	SMART extracellular solute-binding protein family 3	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1912711_2	406817.XNC1_4326	1.145e-06	51.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,1S61K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD)	lsrG	GO:0002952,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016853,GO:0044424,GO:0044444,GO:0044464,GO:0055114	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
SRR25158527_k127_1925126_2	243231.GSU1657	7.071e-24	113.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,43TMI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158527_k127_1925126_0	1125863.JAFN01000001_gene1129	3.837e-180	585.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158527_k127_1925126_1	404589.Anae109_2493	1.382e-44	166.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2YU4B@29|Myxococcales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158527_k127_1926333_1	1173024.KI912148_gene2484	2.605e-17	86.0	COG3491@1|root,COG3491@2|Bacteria,1G3TW@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
SRR25158527_k127_1926333_0	243231.GSU0037	6.139e-123	397.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,43SZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
SRR25158527_k127_1931063_0	596153.Alide_1569	1.38e-67	235.0	COG0431@1|root,COG0431@2|Bacteria,1QU9C@1224|Proteobacteria,2WGJP@28216|Betaproteobacteria,4ADNX@80864|Comamonadaceae	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158527_k127_1931063_1	911045.PSE_1837	1.986e-08	64.0	COG3473@1|root,COG3473@2|Bacteria,1RB05@1224|Proteobacteria,2U5DB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Asp Glu Hydantoin racemase family protein	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158527_k127_1931063_2	633148.Tagg_0582	9.226e-07	53.0	arCOG02240@1|root,arCOG02240@2157|Archaea	2157|Archaea	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158527_k127_1931063_3	317619.ANKN01000043_gene3422	0.0005446	45.0	2EK5Q@1|root,33DW4@2|Bacteria,1GAWH@1117|Cyanobacteria	1117|Cyanobacteria	S	cobalt transporter subunit CbtB	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
SRR25158527_k127_1932852_3	272134.KB731324_gene2628	1.421e-29	125.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158527_k127_1932852_1	1192034.CAP_6251	3.75e-81	283.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1932852_2	1071679.BG57_00435	8.529e-69	237.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VQNI@28216|Betaproteobacteria,1JZMQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Transferase hexapeptide repeat containing protein	paaY	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158527_k127_1932852_0	266779.Meso_2926	1.04e-120	399.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,43KZ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_1934848_1	926690.KE386573_gene182	2.491e-06	55.0	COG1765@1|root,arCOG03686@2157|Archaea,2XYGU@28890|Euryarchaeota,23ST4@183963|Halobacteria	183963|Halobacteria	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158527_k127_1934848_0	1051632.TPY_2012	2.23e-60	225.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158527_k127_1935536_1	1278073.MYSTI_05200	1.612e-13	73.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2YW1W@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158527_k127_1935536_2	234267.Acid_1720	9.355e-05	52.0	COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria	57723|Acidobacteria	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
SRR25158527_k127_1935536_0	1232410.KI421413_gene803	2.721e-113	374.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,43RYY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Leucyl-tRNA synthetase, Domain 2	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158527_k127_193571_0	909663.KI867150_gene247	1.06e-115	380.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158527_k127_193571_1	1532558.JL39_00915	1.796e-54	205.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_193571_2	1510531.JQJJ01000010_gene2351	5.644e-05	45.0	COG2885@1|root,COG2885@2|Bacteria,1R4ZJ@1224|Proteobacteria,2U3AP@28211|Alphaproteobacteria,3JX5P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158527_k127_1939548_1	1144310.PMI07_001955	8.071e-18	93.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,4BCQJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA,TctB
SRR25158527_k127_1939548_0	443152.MDG893_15467	1.824e-48	186.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1940924_1	640081.Dsui_2122	7.031e-14	83.0	COG0715@1|root,COG0715@2|Bacteria,1NF3S@1224|Proteobacteria,2WEG1@28216|Betaproteobacteria,2KVYA@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_1940924_0	289376.THEYE_A2098	2.438e-31	133.0	COG2885@1|root,COG2885@2|Bacteria,3J17Q@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158527_k127_1941251_0	1499967.BAYZ01000176_gene5652	1.227e-88	298.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	ytcB	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158527_k127_1941251_1	269799.Gmet_0923	1.479e-47	177.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,43UQ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR25158527_k127_1941251_2	1499967.BAYZ01000025_gene286	2.701e-35	146.0	COG1663@1|root,COG1663@2|Bacteria,2NPF0@2323|unclassified Bacteria	2|Bacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	LpxK
SRR25158527_k127_1944562_0	671143.DAMO_2468	1.232e-167	533.0	COG0821@1|root,COG0821@2|Bacteria,2NNPV@2323|unclassified Bacteria	2|Bacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430,iJN678.gcpE	GcpE
SRR25158527_k127_1944562_1	880072.Desac_2396	3.541e-67	231.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2MQBJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158527_k127_1959207_0	502025.Hoch_6864	5.681e-154	504.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158527_k127_196597_1	561175.KB894105_gene942	3.819e-43	167.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,4EK24@85012|Streptosporangiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1,SBP_bac_6
SRR25158527_k127_196597_2	1408224.SAMCCGM7_c5123	2.594e-11	75.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2U2F8@28211|Alphaproteobacteria,4BA27@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_8
SRR25158527_k127_196597_0	2074.JNYD01000003_gene3574	5.826e-51	192.0	COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158527_k127_1966963_1	948106.AWZT01000001_gene5077	2.234e-115	387.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2WBWM@28216|Betaproteobacteria,1K6TM@119060|Burkholderiaceae	28216|Betaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_1966963_4	1231391.AMZF01000069_gene2124	5.345e-43	162.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158527_k127_1966963_5	519989.ECTPHS_11632	9.178e-22	104.0	COG0730@1|root,COG0730@2|Bacteria,1RJXP@1224|Proteobacteria,1S5MM@1236|Gammaproteobacteria,1WYSR@135613|Chromatiales	135613|Chromatiales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158527_k127_1966963_2	1274374.CBLK010000066_gene1525	2.09e-80	275.0	COG1335@1|root,COG1335@2|Bacteria,1VA32@1239|Firmicutes,4HKVT@91061|Bacilli,26XP2@186822|Paenibacillaceae	91061|Bacilli	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158527_k127_1966963_3	927677.ALVU02000001_gene2961	4.178e-44	167.0	COG0116@1|root,COG0116@2|Bacteria,1GQF9@1117|Cyanobacteria	1117|Cyanobacteria	L	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_1966963_0	443152.MDG893_15240	1.101e-182	584.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria,1RYIP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
SRR25158527_k127_1968523_1	1034943.BN1094_03603	1.503e-132	428.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNT1@1236|Gammaproteobacteria,1JCTF@118969|Legionellales	118969|Legionellales	C	Citrate synthase, C-terminal domain	prpC	-	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	-	Citrate_synt
SRR25158527_k127_1968523_0	1163617.SCD_n01489	4.94e-220	692.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
SRR25158527_k127_1968523_3	67281.JNZZ01000042_gene3795	3.404e-81	280.0	COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,41CKC@629295|Streptomyces griseus group	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
SRR25158527_k127_1968523_5	1265505.ATUG01000001_gene4613	1.377e-57	213.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,42PMY@68525|delta/epsilon subdivisions,2WPU5@28221|Deltaproteobacteria,2MM4P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
SRR25158527_k127_1968523_4	1121918.ARWE01000001_gene1858	3.005e-74	267.0	COG2114@1|root,COG2114@2|Bacteria,1PFBZ@1224|Proteobacteria,439XJ@68525|delta/epsilon subdivisions,2X1UU@28221|Deltaproteobacteria,43VBR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158527_k127_1968523_7	446468.Ndas_0245	1.022e-11	76.0	COG0454@1|root,COG0456@2|Bacteria,2GMPX@201174|Actinobacteria,4EIME@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158527_k127_1968523_6	1168059.KB899087_gene3882	1.133e-23	117.0	COG3904@1|root,COG3904@2|Bacteria,1RK0H@1224|Proteobacteria,2U4GW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158527_k127_1968523_2	1173026.Glo7428_4957	1.162e-84	294.0	COG0154@1|root,COG0154@2|Bacteria,1G1H1@1117|Cyanobacteria	1117|Cyanobacteria	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	-	ko:K21801	ko00380,ko01100,map00380,map01100	-	-	-	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158527_k127_1973766_0	443152.MDG893_15260	4.669e-47	182.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_1973766_1	1121346.KB899818_gene2527	5.871e-43	164.0	COG0451@1|root,COG0451@2|Bacteria,1TWPP@1239|Firmicutes,4HCTV@91061|Bacilli,26RTK@186822|Paenibacillaceae	91061|Bacilli	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158527_k127_1983720_1	114615.BRADO5499	4.628e-11	72.0	COG0715@1|root,COG0715@2|Bacteria,1NS0V@1224|Proteobacteria,2UI8H@28211|Alphaproteobacteria,3JX4J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1983720_0	525904.Tter_0410	2.312e-91	312.0	COG2055@1|root,COG2055@2|Bacteria,2NQ9A@2323|unclassified Bacteria	2|Bacteria	C	Malate/L-lactate dehydrogenase	comC	-	1.1.1.350	ko:K00073	ko00230,ko01120,map00230,map01120	-	R02935,R02936	RC00169	ko00000,ko00001,ko01000	-	-	-	Ldh_2
SRR25158527_k127_1986880_3	1254432.SCE1572_33770	9.076e-13	70.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,42V73@68525|delta/epsilon subdivisions,2X6NU@28221|Deltaproteobacteria,2YW3N@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158527_k127_1986880_0	443152.MDG893_15065	6.31e-94	318.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,1RQG7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	phtD	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_1986880_2	48698.ENSPFOP00000002186	1.764e-14	78.0	2C27E@1|root,2S2R7@2759|Eukaryota,3A0FP@33154|Opisthokonta,3BQ2T@33208|Metazoa,3D6FG@33213|Bilateria,48EFC@7711|Chordata,49B85@7742|Vertebrata,4A37J@7898|Actinopterygii	33208|Metazoa	S	AhpC/TSA antioxidant enzyme	sell	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
SRR25158527_k127_1986880_1	330214.NIDE3327	1.23e-39	152.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SRR25158527_k127_1989849_0	1173027.Mic7113_2967	2.705e-96	327.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	2|Bacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_1989849_1	1449044.JMLE01000018_gene1664	1.96e-13	79.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_1992481_3	1242864.D187_002092	2.521e-14	79.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria	1224|Proteobacteria	P	metal-dependent hydrolase of the TIM-barrel fold	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_1992481_2	935840.JAEQ01000004_gene646	3.37e-25	117.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_1992481_1	292.DM42_4988	6.365e-42	167.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,2VMPW@28216|Betaproteobacteria,1K62Q@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	3.7.1.9	ko:K10216,ko:K18092	ko00362,ko00622,ko00642,ko00643,ko01100,ko01120,ko01220,map00362,map00622,map00642,map00643,map01100,map01120,map01220	M00569	R02604,R05362,R05366,R05865	RC00272,RC00752,RC00753,RC00754,RC00755,RC01337,RC01485	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158527_k127_1992481_5	1110502.TMO_1189	0.0005206	47.0	COG3806@1|root,COG3806@2|Bacteria,1MZEX@1224|Proteobacteria,2UCQQ@28211|Alphaproteobacteria,2JZRY@204441|Rhodospirillales	204441|Rhodospirillales	T	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
SRR25158527_k127_1992481_0	1120972.AUMH01000006_gene1898	9.761e-74	263.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	ligX	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
SRR25158527_k127_1992481_4	333138.LQ50_20145	3.468e-07	55.0	COG3181@1|root,COG3181@2|Bacteria,1U3ZT@1239|Firmicutes,4IJY9@91061|Bacilli,1ZIAT@1386|Bacillus	91061|Bacilli	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_19982_1	994479.GL877882_gene7036	2.869e-31	135.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4E8ZK@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158527_k127_19982_0	1128421.JAGA01000003_gene3195	2.798e-79	280.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SRR25158527_k127_19982_2	1499967.BAYZ01000003_gene5836	2.49e-19	95.0	COG0457@1|root,COG3577@1|root,COG0457@2|Bacteria,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,TPR_19,gag-asp_proteas
SRR25158527_k127_2004185_0	644966.Tmar_0545	2.439e-210	678.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158527_k127_2004185_2	86416.Clopa_3692	3.063e-06	59.0	COG0715@1|root,COG0715@2|Bacteria,1UR7E@1239|Firmicutes,249SE@186801|Clostridia,36EDF@31979|Clostridiaceae	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family	-	-	-	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	NMT1,NMT1_2
SRR25158527_k127_2004185_1	319225.Plut_1771	1.799e-06	55.0	COG0346@1|root,COG0346@2|Bacteria,1FE30@1090|Chlorobi	1090|Chlorobi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_2004561_0	469383.Cwoe_4081	1.459e-67	240.0	COG1071@1|root,COG1071@2|Bacteria,2IC03@201174|Actinobacteria,4CQ7Q@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM dehydrogenase, E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
SRR25158527_k127_2008396_0	40571.JOEA01000027_gene5927	6.545e-171	551.0	COG2373@1|root,COG2373@2|Bacteria,2GTY9@201174|Actinobacteria,4EAAX@85010|Pseudonocardiales	201174|Actinobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158527_k127_2008396_2	1547437.LL06_20435	3.151e-14	74.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,43IXG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158527_k127_2008396_1	522306.CAP2UW1_2891	4.218e-18	84.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VIN1@28216|Betaproteobacteria,1KR64@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	ET	PFAM extracellular solute-binding protein family 3	aapJ	-	-	ko:K02030,ko:K09969,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
SRR25158527_k127_2014824_0	1120972.AUMH01000030_gene966	2.705e-96	327.0	COG3435@1|root,COG3435@2|Bacteria,1UYG0@1239|Firmicutes,4HCWV@91061|Bacilli,278ZZ@186823|Alicyclobacillaceae	91061|Bacilli	Q	Cupin domain	-	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
SRR25158527_k127_2015622_4	1121346.KB899816_gene3283	5.362e-17	87.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
SRR25158527_k127_2015622_0	1232410.KI421421_gene3865	1.115e-170	547.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43T1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UDP-N-acetylmuramate-L-alanine ligase activity	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158527_k127_2015622_2	1144275.COCOR_06095	1.201e-97	345.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWWJ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158527_k127_2015622_1	1242864.D187_006399	5.083e-102	347.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158527_k127_2015622_3	1379698.RBG1_1C00001G0394	1.737e-25	108.0	COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
SRR25158527_k127_2016885_0	1056820.KB900681_gene2859	6.917e-80	271.0	COG3385@1|root,COG3385@2|Bacteria,1PMXF@1224|Proteobacteria,1RMHK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
SRR25158527_k127_2016885_2	1122915.AUGY01000118_gene6533	7.589e-41	163.0	COG0715@1|root,COG0715@2|Bacteria,1VRJ0@1239|Firmicutes,4HV8W@91061|Bacilli,26U3V@186822|Paenibacillaceae	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2016885_1	1231391.AMZF01000046_gene961	6.342e-42	164.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2020536_1	1236689.MMALV_02080	6.374e-47	179.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,3F2QZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Polyprenyl synthetase	idsA	GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158527_k127_2020536_0	1449080.JQMV01000003_gene2047	1.106e-47	180.0	COG0500@1|root,COG2226@2|Bacteria,1WIUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158527_k127_2020536_3	314230.DSM3645_01776	1.915e-11	74.0	2EEQZ@1|root,338IP@2|Bacteria,2J15B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2020536_2	1255043.TVNIR_1956	7.308e-16	77.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158527_k127_2020897_2	868131.MSWAN_0546	5.069e-35	141.0	COG0500@1|root,arCOG02702@2157|Archaea,2XWS9@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
SRR25158527_k127_2020897_0	330214.NIDE1291	2.726e-229	728.0	COG0210@1|root,COG0210@2|Bacteria,3J0VX@40117|Nitrospirae	40117|Nitrospirae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158527_k127_2020897_1	644966.Tmar_0214	4.34e-104	359.0	COG0421@1|root,COG0421@2|Bacteria,1UI4A@1239|Firmicutes,25GIE@186801|Clostridia	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SRR25158527_k127_2020897_3	237368.SCABRO_01528	5.546e-16	86.0	COG0457@1|root,COG0457@2|Bacteria	237368.SCABRO_01528|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2025090_1	266779.Meso_2926	1.222e-77	268.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,43KZ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_2025090_0	246969.TAM4_600	1.773e-94	323.0	COG3839@1|root,arCOG00177@2157|Archaea,2XTU1@28890|Euryarchaeota	28890|Euryarchaeota	E	COG3842 ABC-type spermidine putrescine transport systems, ATPase components	-	-	3.6.3.29,3.6.3.30,3.6.3.55	ko:K02010,ko:K02017,ko:K15497	ko02010,map02010	M00189,M00190,M00423	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.6.5,3.A.1.8	-	-	ABC_tran,TOBE,TOBE_2
SRR25158527_k127_2025090_2	1231391.AMZF01000063_gene1102	2.777e-16	80.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158527_k127_2028056_1	266264.Rmet_2122	7.542e-13	78.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,1K2JX@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_2028056_0	266265.Bxe_C1059	3.843e-67	235.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,1K3N4@119060|Burkholderiaceae	28216|Betaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158527_k127_2033070_1	880073.Calab_3530	1.661e-71	250.0	COG1004@1|root,COG1004@2|Bacteria,2NNYN@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158527_k127_2033070_0	644282.Deba_0614	2.393e-113	374.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
SRR25158527_k127_2033070_2	316067.Geob_3538	1.844e-48	177.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SRR25158527_k127_2039107_1	671143.DAMO_1683	4.295e-122	397.0	COG0004@1|root,COG0004@2|Bacteria,2NQS8@2323|unclassified Bacteria	2|Bacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iHN637.CLJU_c42670,iYO844.BSU36510	Ammonium_transp
SRR25158527_k127_2039107_0	1121468.AUBR01000046_gene1917	1.027e-222	698.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FXP@68295|Thermoanaerobacterales	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158527_k127_2039107_3	717231.Flexsi_0762	6.834e-50	180.0	COG0347@1|root,COG0347@2|Bacteria,2GFRQ@200930|Deferribacteres	200930|Deferribacteres	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158527_k127_2039107_4	1297742.A176_00649	1.445e-21	101.0	COG5430@1|root,COG5430@2|Bacteria	2|Bacteria	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
SRR25158527_k127_2039107_2	76114.ebA5649	9.127e-78	261.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_204816_3	857293.CAAU_2468	3.211e-16	79.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,36IRH@31979|Clostridiaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158527_k127_204816_1	484770.UFO1_2051	2.247e-41	159.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4H4JF@909932|Negativicutes	909932|Negativicutes	L	RNA methyltransferase RsmD family	rsmD	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
SRR25158527_k127_204816_0	1158292.JPOE01000002_gene2762	4.846e-72	257.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2VJXC@28216|Betaproteobacteria,1KKCS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_204816_2	197221.22294589	4.842e-17	81.0	COG0316@1|root,COG0316@2|Bacteria,1G5QF@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the HesB IscA family	ycf57	GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158527_k127_204851_0	452637.Oter_0309	4.752e-137	457.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,3K76N@414999|Opitutae	2|Bacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158527_k127_204851_2	706587.Desti_3284	1.293e-45	186.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria,2MQQS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158527_k127_204851_1	102125.Xen7305DRAFT_00032160	3.043e-49	181.0	COG0306@1|root,COG0306@2|Bacteria,1G4MA@1117|Cyanobacteria,3VNJJ@52604|Pleurocapsales	1117|Cyanobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158527_k127_2056333_1	1231391.AMZF01000008_gene1529	8.406e-34	141.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2056333_0	485913.Krac_1828	1.815e-44	173.0	COG0596@1|root,COG0596@2|Bacteria,2G8Y9@200795|Chloroflexi	2|Bacteria	S	COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily)	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
SRR25158527_k127_2056333_2	1120972.AUMH01000025_gene2511	1.552e-08	59.0	COG0160@1|root,COG0160@2|Bacteria,1UJDB@1239|Firmicutes,4IT60@91061|Bacilli	91061|Bacilli	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.55,5.1.1.21	ko:K15372,ko:K20708	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
SRR25158527_k127_205708_2	627192.SLG_34970	5.157e-27	115.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske (2Fe-2S) domain-containing protein	-	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
SRR25158527_k127_205708_3	1298860.AUEM01000001_gene1409	1.174e-16	83.0	2B8RU@1|root,3221R@2|Bacteria,2IT3Z@201174|Actinobacteria,4FSCF@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_205708_1	261292.Nit79A3_2588	1.16e-34	134.0	COG2119@1|root,COG2119@2|Bacteria	2|Bacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
SRR25158527_k127_205708_0	1038858.AXBA01000011_gene1462	3.93e-70	248.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
SRR25158527_k127_2057430_1	287986.DV20_27530	2.839e-31	132.0	COG0491@1|root,COG0491@2|Bacteria,2IAXY@201174|Actinobacteria,4E56P@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158527_k127_2057430_0	909663.KI867150_gene2235	1.301e-72	258.0	COG2733@1|root,COG2733@2|Bacteria,1MX3G@1224|Proteobacteria,42UZD@68525|delta/epsilon subdivisions,2WQX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158527_k127_2059144_0	1131269.AQVV01000058_gene1681	7.812e-16	83.0	2EC2G@1|root,3361J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2059144_1	1131814.JAFO01000001_gene2840	4.623e-10	71.0	COG0715@1|root,COG0715@2|Bacteria,1R3SJ@1224|Proteobacteria,2VEU8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_2059144_2	1121403.AUCV01000031_gene2816	6.212e-05	48.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,42QUI@68525|delta/epsilon subdivisions,2WSPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1989)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1989
SRR25158527_k127_2061655_1	1121459.AQXE01000009_gene554	2.014e-85	287.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158527_k127_2061655_0	671143.DAMO_2383	5.365e-277	859.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078	UPF0051
SRR25158527_k127_2061655_2	1201290.M902_1586	1.313e-30	123.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,43ADA@68525|delta/epsilon subdivisions,2MUSB@213481|Bdellovibrionales,2X5SP@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR25158527_k127_2067940_0	1144275.COCOR_04182	2.777e-121	399.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158527_k127_2067940_2	1379698.RBG1_1C00001G0339	2.139e-34	134.0	COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria	2|Bacteria	S	Pfam:DUF59	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158527_k127_2067940_1	237368.SCABRO_03142	3.475e-71	254.0	COG1355@1|root,COG1355@2|Bacteria,2IZEZ@203682|Planctomycetes	203682|Planctomycetes	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SRR25158527_k127_2071463_0	880072.Desac_2293	2.9e-180	575.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MQ7E@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158527_k127_2071463_1	443144.GM21_2975	5.662e-93	314.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,43TZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158527_k127_2078000_0	445971.ANASTE_01161	5.476e-11	74.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,25VGQ@186806|Eubacteriaceae	186801|Clostridia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_2084457_1	247490.KSU1_D0292	1.79e-15	87.0	COG3642@1|root,COG3642@2|Bacteria,2J189@203682|Planctomycetes	203682|Planctomycetes	T	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
SRR25158527_k127_2084457_0	207559.Dde_0844	5.563e-42	166.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2M88U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158527_k127_2084457_2	1041139.KB902724_gene4002	1.336e-07	57.0	COG1216@1|root,COG1216@2|Bacteria,1RKB9@1224|Proteobacteria,2VFC7@28211|Alphaproteobacteria,4BN8R@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158527_k127_2091353_0	671143.DAMO_2859	2.456e-169	536.0	COG0312@1|root,COG0312@2|Bacteria,2NNWH@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158527_k127_2091353_1	671143.DAMO_2858	5.974e-85	292.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	pmbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158527_k127_2091499_2	401053.AciPR4_1793	3.124e-75	256.0	COG1945@1|root,COG1945@2|Bacteria,3Y3KR@57723|Acidobacteria,2JIBD@204432|Acidobacteriia	204432|Acidobacteriia	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
SRR25158527_k127_2091499_3	215803.DB30_4670	7.857e-34	138.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2YVN7@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158527_k127_2091499_1	1168034.FH5T_18240	1.939e-182	584.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,2FMBN@200643|Bacteroidia	976|Bacteroidetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158527_k127_2091499_0	215803.DB30_4665	2.504e-237	747.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YU6I@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SRR25158527_k127_2098391_0	469383.Cwoe_4082	9.93e-120	392.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,4CRBS@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM Transketolase central region	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158527_k127_2098391_1	203124.Tery_2073	9.139e-28	119.0	COG0662@1|root,COG0662@2|Bacteria,1GDUY@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_2098391_2	1202768.JROF01000013_gene891	1.423e-08	65.0	COG0697@1|root,arCOG00272@2157|Archaea,2XUHA@28890|Euryarchaeota,23UY1@183963|Halobacteria	183963|Halobacteria	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_2098524_2	240016.ABIZ01000001_gene671	3.534e-15	80.0	COG0457@1|root,COG0457@2|Bacteria,46VTD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2098524_1	1195246.AGRI_01465	6.035e-16	88.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RYFT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158527_k127_2098524_0	760568.Desku_2265	2.404e-43	164.0	COG3221@1|root,COG3221@2|Bacteria,1U41J@1239|Firmicutes,24NHA@186801|Clostridia,262QZ@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158527_k127_2103893_0	1131269.AQVV01000028_gene28	7.437e-96	346.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
SRR25158527_k127_2108029_0	671143.DAMO_2529	2.791e-35	148.0	COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria	2|Bacteria	D	Peptidase family M23	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158527_k127_2108029_1	398767.Glov_1922	5.362e-17	87.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158527_k127_2110297_0	262316.MAP_1627	4.205e-56	207.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_2110297_1	1366050.N234_12150	2.746e-10	70.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K11210	-	-	-	-	ko00000,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_2112121_0	1231391.AMZF01000121_gene3473	1.088e-22	110.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2112121_1	1487953.JMKF01000072_gene3543	2.682e-20	101.0	COG0596@1|root,COG0596@2|Bacteria,1GQ24@1117|Cyanobacteria,1H7V3@1150|Oscillatoriales	1117|Cyanobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158527_k127_2114195_0	1265310.CCBD010000061_gene1162	4.175e-34	143.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_2114195_1	697303.Thewi_0785	3.78e-23	113.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,42F1C@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158527_k127_2114195_2	580332.Slit_1396	4.9e-08	57.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,44UYC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158527_k127_2116118_0	1123060.JONP01000001_gene1641	1.079e-30	126.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,2JUQX@204441|Rhodospirillales	204441|Rhodospirillales	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158527_k127_2117937_0	102232.GLO73106DRAFT_00028020	1.41e-213	671.0	COG0448@1|root,COG0448@2|Bacteria,1G0IG@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.agp,iSbBS512_1146.agp	NTP_transferase
SRR25158527_k127_2117937_1	1288494.EBAPG3_13270	3.953e-151	488.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,372QJ@32003|Nitrosomonadales	28216|Betaproteobacteria	L	THUMP	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
SRR25158527_k127_2123270_1	1304875.JAFZ01000001_gene743	4.191e-76	266.0	COG1814@1|root,COG1814@2|Bacteria,3TBXB@508458|Synergistetes	508458|Synergistetes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158527_k127_2123270_0	682795.AciX8_0075	9.404e-92	308.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria,2JHRQ@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158527_k127_2123332_2	357808.RoseRS_2742	1.367e-118	391.0	COG2957@1|root,COG2957@2|Bacteria,2GAHD@200795|Chloroflexi,37657@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
SRR25158527_k127_2123332_1	886293.Sinac_3542	5.294e-120	393.0	COG0388@1|root,COG0388@2|Bacteria,2IX91@203682|Planctomycetes	203682|Planctomycetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158527_k127_2123332_7	13035.Dacsa_0686	3.521e-57	208.0	COG0412@1|root,COG0412@2|Bacteria,1G0PH@1117|Cyanobacteria	1117|Cyanobacteria	Q	dienelactone hydrolase	clcD	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_2123332_3	1500257.JQNM01000014_gene2928	2.918e-85	292.0	COG0596@1|root,COG0596@2|Bacteria,1NDHC@1224|Proteobacteria,2UPRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158527_k127_2123332_6	1121423.JONT01000015_gene1349	4.284e-73	256.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SRR25158527_k127_2123332_4	1177179.A11A3_04179	1.27e-83	291.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,1RPM1@1236|Gammaproteobacteria,1XH5M@135619|Oceanospirillales	135619|Oceanospirillales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158527_k127_2123332_0	272134.KB731324_gene2983	1.711e-144	467.0	COG1960@1|root,COG1960@2|Bacteria,1G4X4@1117|Cyanobacteria	1117|Cyanobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_2123332_5	1095769.CAHF01000006_gene1907	2.357e-80	280.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,4770B@75682|Oxalobacteraceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_2123332_8	365046.Rta_29530	8.929e-08	53.0	COG0454@1|root,COG0456@2|Bacteria,1RDVM@1224|Proteobacteria,2VYAK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158527_k127_2124182_1	595460.RRSWK_02053	8.797e-99	330.0	COG0500@1|root,COG2226@2|Bacteria,2IYB6@203682|Planctomycetes	203682|Planctomycetes	Q	Methylase involved in ubiquinone menaquinone	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SRR25158527_k127_2124182_0	880073.Calab_1379	6.573e-130	424.0	COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158527_k127_2124182_3	246197.MXAN_4736	1.804e-26	113.0	COG0319@1|root,COG0662@1|root,COG0319@2|Bacteria,COG0662@2|Bacteria,1MZ67@1224|Proteobacteria,42W3M@68525|delta/epsilon subdivisions,2WRMB@28221|Deltaproteobacteria,2YYJR@29|Myxococcales	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	Cupin_2,UPF0054
SRR25158527_k127_2124182_2	1231391.AMZF01000046_gene961	6.261e-44	173.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2128_0	76114.p2A120	1.111e-113	384.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_2131060_3	330214.NIDE3892	6.509e-15	76.0	2ED3M@1|root,3370H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
SRR25158527_k127_2131060_2	472759.Nhal_2057	1.421e-26	116.0	COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SARP@1236|Gammaproteobacteria,1X16J@135613|Chromatiales	135613|Chromatiales	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
SRR25158527_k127_2131060_0	1121459.AQXE01000007_gene575	7.397e-124	414.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,42U1I@68525|delta/epsilon subdivisions,2WQQV@28221|Deltaproteobacteria,2MA11@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_core,Transglut_i_TM
SRR25158527_k127_2131060_1	105559.Nwat_1944	2.482e-45	168.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales	135613|Chromatiales	HJ	TIGRFAM alpha-L-glutamate ligase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
SRR25158527_k127_2153172_0	330214.NIDE3909	2.396e-104	347.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	iamB	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS,STAS_2
SRR25158527_k127_2153172_1	330214.NIDE3908	6.71e-99	332.0	COG1127@1|root,COG1127@2|Bacteria,3J0J2@40117|Nitrospirae	2|Bacteria	Q	ABC transporter	iamA	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158527_k127_2153172_2	330214.NIDE3907	2.031e-46	172.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	iamC	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158527_k127_2154640_1	756499.Desde_1804	2.272e-10	73.0	COG1652@1|root,COG1652@2|Bacteria,1V54G@1239|Firmicutes,24J28@186801|Clostridia,261QP@186807|Peptococcaceae	186801|Clostridia	V	Cell wall-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LysM
SRR25158527_k127_2154640_0	1173263.Syn7502_03004	3.143e-59	222.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_2154640_3	926554.KI912660_gene2430	2.552e-08	64.0	COG2770@1|root,COG2770@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP
SRR25158527_k127_2154640_2	1297742.A176_02040	4.205e-10	70.0	COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria,42QWX@68525|delta/epsilon subdivisions,2WN80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
SRR25158527_k127_2162149_1	1487953.JMKF01000050_gene1926	5.758e-57	203.0	2CCCK@1|root,2Z7UH@2|Bacteria,1GGQS@1117|Cyanobacteria,1HH0S@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2162149_0	404589.Anae109_4242	4.206e-182	583.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
SRR25158527_k127_2162867_1	273068.TTE0552	5.509e-27	121.0	COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,247QR@186801|Clostridia,42H1C@68295|Thermoanaerobacterales	186801|Clostridia	I	Ndr family	-	-	1.11.1.10,3.1.1.24	ko:K00433,ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158527_k127_2162867_0	94624.Bpet0543	1.594e-43	165.0	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VTAB@28216|Betaproteobacteria	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
SRR25158527_k127_2163224_0	237368.SCABRO_03848	8.638e-87	290.0	COG1127@1|root,COG1127@2|Bacteria,2J2WI@203682|Planctomycetes	203682|Planctomycetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SRR25158527_k127_2163224_1	338963.Pcar_2751	4.443e-82	285.0	COG1463@1|root,COG1463@2|Bacteria,1MYEF@1224|Proteobacteria,42SPY@68525|delta/epsilon subdivisions,2WP3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158527_k127_2163224_2	237368.SCABRO_03846	1.895e-41	161.0	COG3009@1|root,COG3009@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
SRR25158527_k127_2169412_2	1232410.KI421412_gene118	0.0005693	43.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,43SM4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158527_k127_2169412_1	671143.DAMO_2862	4.517e-66	231.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	def2	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158527_k127_2169412_0	1047013.AQSP01000103_gene1160	5.515e-229	719.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158527_k127_2171360_2	330214.NIDE3956	1.218e-18	92.0	COG0424@1|root,COG0424@2|Bacteria	2|Bacteria	D	maF-like protein	maf	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944	2.1.1.190	ko:K03215,ko:K06287	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Maf
SRR25158527_k127_2171360_1	330214.NIDE3957	3.42e-114	380.0	COG0042@1|root,COG0042@2|Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
SRR25158527_k127_2171360_0	1201288.M900_A0332	4.248e-130	422.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2MSKZ@213481|Bdellovibrionales,2WKJ6@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158527_k127_2171484_0	479434.Sthe_1925	2.706e-89	311.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,27YWM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158527_k127_2179609_0	402626.Rpic_0855	1.344e-96	322.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2VN9Y@28216|Betaproteobacteria,1K6AS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158527_k127_2179609_2	1123508.JH636442_gene4074	3.394e-25	107.0	COG2055@1|root,COG2055@2|Bacteria,2J36Z@203682|Planctomycetes	203682|Planctomycetes	C	Malate/L-lactate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
SRR25158527_k127_2179609_1	1173263.Syn7502_03002	3.018e-33	136.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H2GH@1129|Synechococcus	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR25158527_k127_2182451_0	880072.Desac_2282	4.408e-96	330.0	COG1752@1|root,COG1752@2|Bacteria,1PGY0@1224|Proteobacteria,42MKJ@68525|delta/epsilon subdivisions,2WK4M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SRR25158527_k127_2182451_1	195250.CM001776_gene3730	1.051e-39	151.0	2BB59@1|root,324MR@2|Bacteria,1GH75@1117|Cyanobacteria,1H3IB@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2182556_0	483219.LILAB_28375	6.551e-86	308.0	COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2YX57@29|Myxococcales	28221|Deltaproteobacteria	T	CHASE3 domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
SRR25158527_k127_2185820_0	56780.SYN_01931	2.517e-153	499.0	COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria,2MQYM@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
SRR25158527_k127_2187751_0	671143.DAMO_0072	1.471e-193	615.0	COG1220@1|root,COG1220@2|Bacteria,2NP00@2323|unclassified Bacteria	2|Bacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
SRR25158527_k127_2187751_1	1232410.KI421428_gene1164	8.95e-117	384.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,43SC9@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Amino acid kinase family	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158527_k127_2188647_2	502025.Hoch_5503	2.416e-17	85.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,42SFZ@68525|delta/epsilon subdivisions,2WPY5@28221|Deltaproteobacteria,2Z0Z7@29|Myxococcales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158527_k127_2188647_0	443143.GM18_2682	9.308e-105	345.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2WIPU@28221|Deltaproteobacteria,43UK1@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158527_k127_2188647_1	330214.NIDE2666	4.482e-60	214.0	COG2096@1|root,COG2096@2|Bacteria	2|Bacteria	S	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.2.1.88,1.5.5.2,2.5.1.17	ko:K00798,ko:K13821	ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130	M00122	R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268	RC00080,RC00083,RC00216,RC00242,RC00255,RC00533	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Cob_adeno_trans
SRR25158527_k127_2188647_3	886293.Sinac_6857	2.021e-16	80.0	COG0531@1|root,COG0531@2|Bacteria,2IY9I@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158527_k127_2190508_0	887062.HGR_01934	2.222e-206	659.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,4ABU5@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158527_k127_2194009_1	1097668.BYI23_C006780	1.147e-55	202.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2VMR4@28216|Betaproteobacteria,1KI47@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158527_k127_2194009_0	1532557.JL37_16745	1.412e-119	397.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2W1IE@28216|Betaproteobacteria,3T1DH@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158527_k127_2194009_2	710686.Mycsm_01832	1.847e-18	94.0	COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria	201174|Actinobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
SRR25158527_k127_2206229_1	1387312.BAUS01000001_gene1152	1.786e-05	56.0	COG0515@1|root,COG0515@2|Bacteria,1QU0D@1224|Proteobacteria,2VU0E@28216|Betaproteobacteria,2KMSZ@206350|Nitrosomonadales	206350|Nitrosomonadales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
SRR25158527_k127_2206229_0	314345.SPV1_01907	8.597e-19	95.0	COG0500@1|root,COG2226@2|Bacteria,1N1HA@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SRR25158527_k127_2206229_2	1125863.JAFN01000001_gene543	2.731e-05	51.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158527_k127_2207575_0	760568.Desku_2852	3.043e-226	713.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,261BK@186807|Peptococcaceae	186801|Clostridia	G	Domain of unknown function (DUF3459)	-	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
SRR25158527_k127_2214346_0	1380394.JADL01000012_gene856	8.051e-149	492.0	28JZQ@1|root,2Z9PN@2|Bacteria,1N2WN@1224|Proteobacteria,2U0QD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_221618_2	909663.KI867150_gene1012	2.915e-82	281.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,42PZC@68525|delta/epsilon subdivisions,2WK59@28221|Deltaproteobacteria,2MQUU@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158527_k127_221618_1	1379698.RBG1_1C00001G1666	3.327e-99	328.0	COG1136@1|root,COG1136@2|Bacteria,2NPA8@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158527_k127_221618_0	1379698.RBG1_1C00001G1665	2.211e-102	346.0	COG0845@1|root,COG0845@2|Bacteria,2NQ2U@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	acrA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158527_k127_2216833_1	261292.Nit79A3_3059	2.813e-56	199.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VU64@28216|Betaproteobacteria,3738I@32003|Nitrosomonadales	28216|Betaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
SRR25158527_k127_2216833_0	404589.Anae109_0592	1.718e-160	509.0	COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158527_k127_2216833_3	1123248.KB893316_gene4667	2.597e-39	149.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1ITAW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158527_k127_2216833_4	1254432.SCE1572_01750	2.805e-10	62.0	COG3832@1|root,COG3832@2|Bacteria,1N3W1@1224|Proteobacteria,430BD@68525|delta/epsilon subdivisions,2WVPP@28221|Deltaproteobacteria,2YVKM@29|Myxococcales	28221|Deltaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158527_k127_2216833_2	330214.NIDE3487	2.716e-47	172.0	COG4941@1|root,COG4941@2|Bacteria	2|Bacteria	K	sigma factor activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158527_k127_2220079_3	477228.YO5_02458	4.533e-16	79.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1Z0TH@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
SRR25158527_k127_2220079_2	338963.Pcar_0999	3.185e-76	266.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,43SDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SRR25158527_k127_2220079_4	1118059.CAHC01000008_gene1239	5.702e-08	64.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,3WCNK@538999|Clostridiales incertae sedis	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SRR25158527_k127_2220079_0	404380.Gbem_2635	4.721e-170	548.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158527_k127_2220079_1	1469607.KK073768_gene4663	1.546e-143	464.0	COG3547@1|root,COG3547@2|Bacteria,1GA7N@1117|Cyanobacteria,1HTM7@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158527_k127_2255079_1	266779.Meso_4473	2.006e-42	165.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_2255079_2	227086.JGI_V11_91178	0.0001119	52.0	2C3YR@1|root,2S9YS@2759|Eukaryota	2759|Eukaryota	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
SRR25158527_k127_2255079_0	1088721.NSU_3568	2.034e-68	250.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,2K1FR@204457|Sphingomonadales	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SRR25158527_k127_2256634_1	330214.NIDE2073	3.624e-168	537.0	COG1389@1|root,COG1389@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
SRR25158527_k127_2256634_0	330214.NIDE2074	3.25e-191	601.0	COG1697@1|root,COG1697@2|Bacteria	2|Bacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF2220,DUF3322,TP6A_N
SRR25158527_k127_2259903_3	251229.Chro_4254	9.972e-18	85.0	COG0500@1|root,COG0500@2|Bacteria,1GR1R@1117|Cyanobacteria	1117|Cyanobacteria	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_2259903_2	1231391.AMZF01000046_gene961	1.954e-44	175.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2259903_0	756067.MicvaDRAFT_2506	0.0	1068.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158527_k127_2259903_1	756067.MicvaDRAFT_2507	3.454e-62	222.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Formyl_trans_N,Methyltransf_12,PP-binding,PilZ
SRR25158527_k127_2263846_1	1382356.JQMP01000001_gene834	1.024e-45	170.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2263846_0	643648.Slip_1084	3.358e-49	182.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,42JV3@68298|Syntrophomonadaceae	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158527_k127_2263846_2	247490.KSU1_D0201	6.526e-23	102.0	COG0399@1|root,COG0399@2|Bacteria,2J1H7@203682|Planctomycetes	203682|Planctomycetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158527_k127_2266115_0	443152.MDG893_15307	1.4e-108	363.0	2C1EV@1|root,33RW1@2|Bacteria,1R3AA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2275399_0	468556.AQYG01000051_gene2319	7.507e-35	149.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria,4GAC0@85026|Gordoniaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_2275399_2	378806.STAUR_3029	1.724e-07	62.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_2275399_1	1463903.JOIZ01000003_gene1713	4.541e-29	121.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
SRR25158527_k127_2276507_2	309801.trd_A0669	1.083e-84	289.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi,27Y3J@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_2276507_1	675635.Psed_3034	8.124e-110	374.0	COG5016@1|root,COG5016@2|Bacteria,2IA4P@201174|Actinobacteria	201174|Actinobacteria	C	Conserved carboxylase domain	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
SRR25158527_k127_2276507_3	402777.KB235898_gene5456	4.091e-18	91.0	COG1051@1|root,COG1051@2|Bacteria,1G6Z3@1117|Cyanobacteria,1HBK4@1150|Oscillatoriales	1117|Cyanobacteria	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158527_k127_2276507_0	269799.Gmet_1215	0.0	1209.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43SUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158527_k127_2283309_1	457398.HMPREF0326_01686	6.757e-11	65.0	2DMKU@1|root,32S9Z@2|Bacteria,1QANK@1224|Proteobacteria,43696@68525|delta/epsilon subdivisions,2X0TS@28221|Deltaproteobacteria,2MDDS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Selenoprotein B glycine betaine sarcosine D-proline reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2283309_0	891968.Anamo_0400	5.067e-101	339.0	COG1978@1|root,COG1978@2|Bacteria,3TA3Z@508458|Synergistetes	508458|Synergistetes	S	Selenoprotein B, glycine betaine sarcosine D-proline reductase family	-	-	1.21.4.2	ko:K10672	-	-	-	-	ko00000,ko01000	-	-	-	GRDB
SRR25158527_k127_2283309_2	584708.Apau_2303	2.731e-09	64.0	28HF7@1|root,2Z7RC@2|Bacteria,3TAHT@508458|Synergistetes	508458|Synergistetes	C	PFAM Glycine sarcosine betaine reductase component B subunits	-	-	1.21.4.2	ko:K10671	-	-	-	-	ko00000,ko01000	-	-	-	Gly_reductase
SRR25158527_k127_2293805_0	330779.Saci_2055	1.807e-11	69.0	COG0043@1|root,arCOG01671@2157|Archaea,2XPU8@28889|Crenarchaeota	28889|Crenarchaeota	H	TIGRFAM UbiD family	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_2293805_1	1206720.BAFQ01000297_gene6724	4.182e-08	64.0	29EVM@1|root,301TC@2|Bacteria,2I8GN@201174|Actinobacteria,4G5Z7@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2302129_0	330214.NIDE3892	5.31e-38	147.0	2ED3M@1|root,3370H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
SRR25158527_k127_2302129_2	1121441.AUCX01000003_gene2974	1.252e-14	86.0	COG1271@1|root,COG1271@2|Bacteria,1QXQF@1224|Proteobacteria,42NKJ@68525|delta/epsilon subdivisions,2WKHM@28221|Deltaproteobacteria,2M95S@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	oxidase subunit	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	-
SRR25158527_k127_2302129_1	1157490.EL26_13140	7.574e-15	79.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1V01J@1239|Firmicutes,4HEV4@91061|Bacilli,279FV@186823|Alicyclobacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158527_k127_2323976_0	795666.MW7_1228	9.031e-91	317.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,1K0X6@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158527_k127_2323976_1	265729.GS18_0207185	4.09e-36	142.0	COG4276@1|root,COG4276@2|Bacteria,1V57F@1239|Firmicutes,4HJWD@91061|Bacilli,1ZFN8@1386|Bacillus	91061|Bacilli	S	Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158527_k127_2323976_2	1267533.KB906735_gene4864	1.189e-12	70.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158527_k127_2331051_1	880072.Desac_1681	2.852e-52	190.0	COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria	1224|Proteobacteria	J	Methionyl-tRNA formyltransferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158527_k127_2331051_3	234267.Acid_3196	1.952e-06	52.0	COG1598@1|root,COG1598@2|Bacteria,3Y8ZR@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2331051_2	243090.RB3259	1.35e-13	72.0	COG1724@1|root,COG1724@2|Bacteria,2J477@203682|Planctomycetes	203682|Planctomycetes	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SRR25158527_k127_2331051_0	296591.Bpro_3467	1.824e-57	203.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,4ABP9@80864|Comamonadaceae	28216|Betaproteobacteria	C	Luciferase family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_2335227_4	1267005.KB911258_gene543	1.029e-16	79.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,2UKKG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2335227_0	652103.Rpdx1_3267	1.117e-65	226.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,3JY5H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158527_k127_2335227_3	663610.JQKO01000009_gene413	8.377e-27	113.0	2DQEY@1|root,336EY@2|Bacteria,1N0JJ@1224|Proteobacteria,2UGD9@28211|Alphaproteobacteria,3NBUU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2335227_2	1408444.JHYC01000010_gene1614	1.202e-37	145.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,1SDT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
SRR25158527_k127_2335227_1	1336243.JAEA01000005_gene1293	2.62e-45	167.0	29YH7@1|root,30KC6@2|Bacteria,1PHBN@1224|Proteobacteria,2VA9N@28211|Alphaproteobacteria,1JYNI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2853
SRR25158527_k127_2335227_5	331869.BAL199_03339	5.559e-12	71.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158527_k127_2336559_0	1424334.W822_02025	1.429e-14	85.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2336559_1	1231391.AMZF01000020_gene1928	0.0001307	48.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2338598_0	1231391.AMZF01000094_gene122	2.394e-174	563.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_2338598_1	1041138.KB890256_gene3545	6.145e-20	98.0	COG2084@1|root,COG2084@2|Bacteria,1MV27@1224|Proteobacteria,2TTCZ@28211|Alphaproteobacteria,4B96S@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
SRR25158527_k127_2339717_0	1056820.KB900634_gene1890	2.994e-27	120.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,1SC68@1236|Gammaproteobacteria,2PQ3C@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	I	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158527_k127_2339717_1	360910.BAV0730	8.033e-17	84.0	COG1917@1|root,COG1917@2|Bacteria,1RJBF@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2
SRR25158527_k127_2339717_2	1236959.BAMT01000013_gene3027	6.8e-06	53.0	2DWDH@1|root,33ZT5@2|Bacteria,1QW4I@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158527_k127_234316_3	487521.OCU_15350	2.297e-07	59.0	COG0346@1|root,COG0346@2|Bacteria,2GW68@201174|Actinobacteria,23D7F@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_234316_2	234267.Acid_7243	2.667e-54	204.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15,1.1.3.46	ko:K00104,ko:K16422	ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130	-	R00475,R06633	RC00042,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
SRR25158527_k127_234316_0	660470.Theba_1523	6.048e-58	210.0	COG1704@1|root,COG1704@2|Bacteria,2GCV5@200918|Thermotogae	200918|Thermotogae	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SRR25158527_k127_234316_1	266117.Rxyl_0345	1.693e-57	212.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CQF1@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158527_k127_2346271_3	240292.Ava_2563	9.034e-08	57.0	COG0642@1|root,COG0745@1|root,COG4252@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG4252@2|Bacteria,1G3JA@1117|Cyanobacteria,1HJCM@1161|Nostocales	1117|Cyanobacteria	T	Integral membrane sensor hybrid histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA,Response_reg
SRR25158527_k127_2346271_2	1267005.KB911255_gene2387	2.994e-09	59.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158527_k127_2346271_1	1231391.AMZF01000046_gene961	2.448e-23	113.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2346271_0	1231391.AMZF01000063_gene1102	5.614e-46	178.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158527_k127_2363264_2	1167006.UWK_02821	3.133e-15	81.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2MI1U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158527_k127_2363264_0	1232410.KI421422_gene2079	2.486e-83	283.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,43S4Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SRR25158527_k127_2363264_1	153721.MYP_4398	1.642e-37	143.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,47M5H@768503|Cytophagia	976|Bacteroidetes	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
SRR25158527_k127_2366459_0	768671.ThimaDRAFT_3635	5.125e-41	154.0	2C3ZQ@1|root,32SCF@2|Bacteria,1N27R@1224|Proteobacteria,1S4HC@1236|Gammaproteobacteria,1X16N@135613|Chromatiales	135613|Chromatiales	S	MEKHLA domain	-	-	-	-	-	-	-	-	-	-	-	-	MEKHLA
SRR25158527_k127_2366459_1	1121385.AQXW01000004_gene2733	2.937e-32	141.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria,1ZWM6@145357|Dermacoccaceae	201174|Actinobacteria	EGP	MFS/sugar transport protein	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158527_k127_2380436_1	247490.KSU1_C0105	6.956e-28	118.0	COG0517@1|root,COG0517@2|Bacteria,2J4UJ@203682|Planctomycetes	203682|Planctomycetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158527_k127_2380436_0	1121405.dsmv_1861	8.599e-109	363.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MIS4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,PTS_EIIA_2
SRR25158527_k127_2393959_3	1123269.NX02_18155	2.167e-37	145.0	COG4254@1|root,COG4254@2|Bacteria,1N739@1224|Proteobacteria,2TY9V@28211|Alphaproteobacteria,2K5CY@204457|Sphingomonadales	204457|Sphingomonadales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SRR25158527_k127_2393959_4	159087.Daro_1992	9.748e-34	139.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,2VU4E@28216|Betaproteobacteria,2KZ0C@206389|Rhodocyclales	206389|Rhodocyclales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SRR25158527_k127_2393959_0	1198452.Jab_2c08620	1.615e-131	445.0	COG2208@1|root,COG4252@1|root,COG2208@2|Bacteria,COG4252@2|Bacteria,1QUNZ@1224|Proteobacteria,2WEJF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,SpoIIE
SRR25158527_k127_2393959_1	1122604.JONR01000009_gene2309	1.426e-104	350.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158527_k127_2393959_6	56780.SYN_02357	4.093e-20	97.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,42V4M@68525|delta/epsilon subdivisions,2WRKJ@28221|Deltaproteobacteria,2MS4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	anti-sigma regulatory factor	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158527_k127_2393959_5	1122604.JONR01000009_gene2308	2.541e-21	97.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,1SHX0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
SRR25158527_k127_2393959_2	1192034.CAP_7850	1.897e-52	198.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42PNH@68525|delta/epsilon subdivisions,2WKTT@28221|Deltaproteobacteria,2YUTB@29|Myxococcales	28221|Deltaproteobacteria	EH	Belongs to the TPP enzyme family	alsS	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_2395049_0	1303518.CCALI_01156	6.379e-73	262.0	COG0248@1|root,COG0248@2|Bacteria	2|Bacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
SRR25158527_k127_2401545_1	330214.NIDE2085	1.775e-24	110.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
SRR25158527_k127_2401545_0	330214.NIDE2086	2.807e-201	661.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158527_k127_2409354_1	926560.KE387027_gene713	1.022e-48	181.0	COG2303@1|root,COG2303@2|Bacteria,1WMTM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158527_k127_2409354_0	886293.Sinac_3644	1.151e-130	426.0	COG3673@1|root,COG3673@2|Bacteria,2J3YE@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
SRR25158527_k127_2409354_2	1429046.RR21198_5303	1.756e-05	47.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,4FXFF@85025|Nocardiaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,TspO_MBR
SRR25158527_k127_2411067_0	1380394.JADL01000013_gene703	1.506e-58	214.0	COG0667@1|root,COG0667@2|Bacteria,1R5BH@1224|Proteobacteria,2TS0A@28211|Alphaproteobacteria,2JVHZ@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158527_k127_2411067_1	861299.J421_2552	7.534e-33	136.0	COG0546@1|root,COG0546@2|Bacteria,1ZTK9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158527_k127_2412920_0	118168.MC7420_4295	7.584e-139	451.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158527_k127_2412920_1	1382306.JNIM01000001_gene3478	1.002e-112	383.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N,adh_short
SRR25158527_k127_2412920_3	479434.Sthe_3372	2.522e-97	336.0	COG2079@1|root,COG2079@2|Bacteria,2G8X4@200795|Chloroflexi,27Z98@189775|Thermomicrobia	189775|Thermomicrobia	S	MmgE/PrpD family	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
SRR25158527_k127_2412920_2	558169.AGAV01000018_gene3526	9.539e-100	337.0	COG3181@1|root,COG3181@2|Bacteria,1UY6C@1239|Firmicutes,4HERV@91061|Bacilli	91061|Bacilli	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2423022_0	1382306.JNIM01000001_gene1659	7.545e-127	416.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi	200795|Chloroflexi	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158527_k127_2423022_1	543728.Vapar_6059	2.621e-44	164.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,2VWHW@28216|Betaproteobacteria,4AIJP@80864|Comamonadaceae	28216|Betaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.5.4.44	ko:K15783	ko00260,ko01100,map00260,map01100	-	R09800	RC02661	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_2423215_1	1121918.ARWE01000001_gene3000	1.604e-07	54.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158527_k127_2423215_0	1191523.MROS_0859	2.336e-281	876.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158527_k127_2433957_0	1125863.JAFN01000001_gene205	9.113e-92	323.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SRR25158527_k127_2433957_1	56780.SYN_01706	1.733e-69	244.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S1C family	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158527_k127_2436003_0	285535.JOEY01000008_gene8811	5e-09	67.0	29EVM@1|root,301TC@2|Bacteria,2I8GN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2436003_1	762376.AXYL_06680	7.443e-08	57.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2VHMD@28216|Betaproteobacteria,3T28I@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158527_k127_2436051_0	1173263.Syn7502_03004	3.147e-34	146.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_2436051_1	1499686.BN1079_01428	1.581e-05	48.0	COG3473@1|root,COG3473@2|Bacteria,1N3F7@1224|Proteobacteria	1224|Proteobacteria	Q	Catalyzes the conversion of maleate to fumarate	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158527_k127_2438513_1	471857.Svir_15320	2.885e-74	260.0	COG1052@1|root,COG1052@2|Bacteria,2I2IC@201174|Actinobacteria,4E09H@85010|Pseudonocardiales	201174|Actinobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	serA2	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158527_k127_2438513_0	587753.EY04_00670	1.324e-75	257.0	COG0500@1|root,COG2226@2|Bacteria,1QU8Z@1224|Proteobacteria,1RS1E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SRR25158527_k127_2445530_3	1123258.AQXZ01000019_gene2668	2.852e-05	48.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4FZM2@85025|Nocardiaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_2445530_2	321327.CYA_1203	3.317e-50	188.0	COG1011@1|root,COG1011@2|Bacteria,1G51I@1117|Cyanobacteria,1H0H2@1129|Synechococcus	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
SRR25158527_k127_2445530_0	243231.GSU2290	3.325e-71	245.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,42TFN@68525|delta/epsilon subdivisions,2WP7M@28221|Deltaproteobacteria,43SNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SRR25158527_k127_2445530_1	1356854.N007_12390	3.256e-50	189.0	COG0483@1|root,COG0483@2|Bacteria,1UKWB@1239|Firmicutes,4ITKN@91061|Bacilli	91061|Bacilli	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158527_k127_2455208_6	439375.Oant_3612	6.274e-09	58.0	COG0239@1|root,COG0239@2|Bacteria,1N3EB@1224|Proteobacteria,2VAMB@28211|Alphaproteobacteria,1J3B6@118882|Brucellaceae	28211|Alphaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	-	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
SRR25158527_k127_2455208_2	880073.Calab_0541	1.87e-45	169.0	COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria	2|Bacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
SRR25158527_k127_2455208_0	460265.Mnod_4947	2.689e-55	201.0	COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,2TSKK@28211|Alphaproteobacteria,1JUQS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Pyridoxamine 5'-phosphate	MA20_21430	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158527_k127_2455208_3	243231.GSU1541	2.626e-20	92.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,42QPI@68525|delta/epsilon subdivisions,2WMUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158527_k127_2455208_1	497321.C664_19758	1.585e-48	183.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,2VR9H@28216|Betaproteobacteria,2KX77@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
SRR25158527_k127_2455208_5	1189620.AJXL01000014_gene863	2.985e-11	66.0	COG2733@1|root,COG2733@2|Bacteria,4NI4B@976|Bacteroidetes,1HY8I@117743|Flavobacteriia,2NT13@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
SRR25158527_k127_245990_0	1287276.X752_16010	1.99e-156	509.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SRR25158527_k127_245990_1	3847.GLYMA02G08180.1	3.538e-12	66.0	COG1249@1|root,KOG0405@2759|Eukaryota,37JH7@33090|Viridiplantae,3GCDE@35493|Streptophyta,4JGNA@91835|fabids	35493|Streptophyta	Q	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	GO:0000302,GO:0000305,GO:0003674,GO:0003824,GO:0004362,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0042221,GO:0042579,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158527_k127_2487063_0	1231391.AMZF01000063_gene1104	4.431e-121	406.0	COG4819@1|root,COG4819@2|Bacteria,1PPGT@1224|Proteobacteria	1224|Proteobacteria	E	ethanolamine utilization protein	eutA	GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
SRR25158527_k127_2487063_1	886293.Sinac_1831	1.004e-08	57.0	COG1290@1|root,COG1290@2|Bacteria,2IYI0@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158527_k127_248728_1	414684.RC1_0236	2.453e-15	82.0	COG3573@1|root,COG3573@2|Bacteria,1R00Y@1224|Proteobacteria	1224|Proteobacteria	C	FAD dependent oxidoreductase	-	-	-	ko:K07077	-	-	-	-	ko00000	-	-	-	FAD_binding_2
SRR25158527_k127_248728_0	935840.JAEQ01000004_gene646	4.899e-20	102.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,43JZT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_2488360_1	306281.AJLK01000102_gene3420	3.082e-30	121.0	28JPA@1|root,2Z9FC@2|Bacteria,1G2DB@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2488360_0	1231391.AMZF01000020_gene1928	3.719e-38	157.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_2488360_2	118161.KB235922_gene3802	4.583e-10	68.0	COG0662@1|root,COG0662@2|Bacteria,1GDUY@1117|Cyanobacteria	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_2498557_4	243231.GSU0815	1.698e-18	87.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SRR25158527_k127_2498557_2	671143.DAMO_2217	2.303e-49	183.0	COG2854@1|root,COG2854@2|Bacteria	2|Bacteria	Q	intermembrane phospholipid transfer	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR25158527_k127_2498557_3	702113.PP1Y_AT11785	3.182e-21	106.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria,2K3JD@204457|Sphingomonadales	204457|Sphingomonadales	S	Amidohydrolase	-	-	4.1.1.46	ko:K14333	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R00821	RC00390	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
SRR25158527_k127_2498557_0	926569.ANT_17660	4.96e-148	479.0	COG0579@1|root,COG0579@2|Bacteria,2G67E@200795|Chloroflexi	200795|Chloroflexi	S	FAD dependent oxidoreductase	-	-	1.1.99.2	ko:K00109,ko:K15736	ko00650,map00650	-	R03534	RC00031	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158527_k127_2498557_1	386456.JQKN01000018_gene606	1.974e-50	197.0	COG0477@1|root,arCOG00143@2157|Archaea,2Y78W@28890|Euryarchaeota,23PF2@183925|Methanobacteria	183925|Methanobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_2503499_1	684719.HIMB114_00002750	0.0003668	51.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
SRR25158527_k127_2503499_0	1134413.ANNK01000086_gene318	2.153e-41	156.0	COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus	91061|Bacilli	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_2506654_2	983917.RGE_32800	1.427e-09	65.0	COG2128@1|root,COG2128@2|Bacteria,1NC6E@1224|Proteobacteria,2WFTS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	-
SRR25158527_k127_2506654_1	266117.Rxyl_0244	1.273e-57	217.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4CRDP@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
SRR25158527_k127_2506654_0	1201288.M900_1378	2.877e-93	317.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,42QEX@68525|delta/epsilon subdivisions,2MSY0@213481|Bdellovibrionales,2WMFU@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158527_k127_2507782_6	392499.Swit_4134	0.0006436	46.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2TRVU@28211|Alphaproteobacteria,2K8WS@204457|Sphingomonadales	204457|Sphingomonadales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158527_k127_2507782_0	702113.PP1Y_AT33092	1.007e-72	256.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,2K1BU@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM amidohydrolase 2	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR25158527_k127_2507782_4	1121918.ARWE01000001_gene1281	1.139e-15	90.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42KZQ@68525|delta/epsilon subdivisions,2WK0Z@28221|Deltaproteobacteria,43S1J@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158527_k127_2507782_3	868864.Dester_0582	6.603e-29	124.0	COG1502@1|root,COG1502@2|Bacteria,2G44G@200783|Aquificae	200783|Aquificae	I	SMART phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158527_k127_2507782_5	386456.JQKN01000001_gene2361	2.729e-05	53.0	arCOG03400@1|root,arCOG03400@2157|Archaea,2XZZ2@28890|Euryarchaeota,23P7G@183925|Methanobacteria	183925|Methanobacteria	S	Nucleic acid binding	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_anti-codon,tRNA_anti_2
SRR25158527_k127_2507782_1	635013.TherJR_2200	8.237e-64	234.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,2607W@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158527_k127_2507782_2	795797.C497_16127	2.349e-47	177.0	COG1234@1|root,arCOG00500@2157|Archaea	2157|Archaea	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
SRR25158527_k127_2515132_2	1131269.AQVV01000038_gene1564	1.088e-25	108.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158527_k127_2515132_1	352165.HMPREF7215_0008	1.488e-63	229.0	COG0248@1|root,COG0248@2|Bacteria,3TB1X@508458|Synergistetes	508458|Synergistetes	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158527_k127_2515132_0	330214.NIDE0295	9.882e-66	229.0	COG1206@1|root,COG1206@2|Bacteria,3J0WT@40117|Nitrospirae	40117|Nitrospirae	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SRR25158527_k127_2518233_2	1033734.CAET01000059_gene1921	1.558e-18	87.0	COG2215@1|root,COG2215@2|Bacteria,1VA77@1239|Firmicutes,4HM1V@91061|Bacilli,1ZC90@1386|Bacillus	91061|Bacilli	S	PFAM Nickel cobalt transporter, high-affinity	ureH	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
SRR25158527_k127_2518233_1	479434.Sthe_0748	1.05e-40	154.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158527_k127_2518233_3	383372.Rcas_2923	1.337e-14	79.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,376I2@32061|Chloroflexia	32061|Chloroflexia	H	PFAM molybdopterin biosynthesis MoaE protein	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
SRR25158527_k127_2518233_0	330214.NIDE2773	3.926e-56	201.0	COG0521@1|root,COG0521@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
SRR25158527_k127_2519345_0	756067.MicvaDRAFT_1231	1.265e-280	876.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158527_k127_2519345_1	1117379.BABA_03774	0.0006108	48.0	COG2021@1|root,COG2021@2|Bacteria,1UN0R@1239|Firmicutes,4IUMT@91061|Bacilli,1ZSGR@1386|Bacillus	91061|Bacilli	E	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158527_k127_2524039_0	981384.AEYW01000003_gene2115	8.24e-11	64.0	COG0726@1|root,COG3195@1|root,COG0726@2|Bacteria,COG3195@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,4NAEF@97050|Ruegeria	28211|Alphaproteobacteria	G	OHCU decarboxylase	uraD	-	3.5.1.41	ko:K01452	ko00520,ko01100,map00520,map01100	-	R02333	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	OHCU_decarbox,Polysacc_deac_1
SRR25158527_k127_2526931_1	215803.DB30_7109	7.969e-128	415.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158527_k127_2526931_0	56780.SYN_00437	1.313e-142	464.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2MQ7W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158527_k127_2528234_2	743299.Acife_2488	3.386e-14	77.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2NCKS@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_2528234_0	909663.KI867150_gene433	8.79e-72	252.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158527_k127_2528234_3	1216976.AX27061_4092	2.892e-06	55.0	2EG5Q@1|root,339XK@2|Bacteria,1NGQ6@1224|Proteobacteria,2WA6Y@28216|Betaproteobacteria,3T4T8@506|Alcaligenaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4168)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4168
SRR25158527_k127_2528234_1	247490.KSU1_C1261	1.465e-15	78.0	COG2854@1|root,COG2854@2|Bacteria,2J2VT@203682|Planctomycetes	203682|Planctomycetes	Q	MlaC protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaC
SRR25158527_k127_2528820_3	1189612.A33Q_1925	5.047e-05	47.0	COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,47JGG@768503|Cytophagia	976|Bacteroidetes	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_2528820_2	1144310.PMI07_004507	3.952e-17	93.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,4B98I@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_2528820_0	1144310.PMI07_001954	3.24e-52	198.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2528820_1	392499.Swit_2091	3.887e-37	145.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2U2SV@28211|Alphaproteobacteria,2K9WC@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158527_k127_2545681_1	1297863.APJF01000030_gene829	1.507e-67	235.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	MA20_23145	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
SRR25158527_k127_2545681_2	645991.Sgly_0970	9.278e-11	73.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,24D4Q@186801|Clostridia,262FA@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,OmpA
SRR25158527_k127_2545681_0	324602.Caur_3563	1.865e-83	290.0	COG0477@1|root,COG2814@2|Bacteria,2GBHK@200795|Chloroflexi,376GU@32061|Chloroflexia	32061|Chloroflexia	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_2548226_1	1267580.AF6_0338	6.654e-44	166.0	COG0388@1|root,COG0388@2|Bacteria,1U0VJ@1239|Firmicutes,4HTZ3@91061|Bacilli	91061|Bacilli	S	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2548226_0	1205680.CAKO01000008_gene4212	3.855e-86	301.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRR25158527_k127_2551842_2	443152.MDG893_15295	1.549e-13	73.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2551842_0	443152.MDG893_15260	5.203e-25	117.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2551842_1	1123322.KB904678_gene3191	5.065e-16	89.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_2554089_0	56780.SYN_01568	4.057e-93	316.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,2MQC0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SRR25158527_k127_2554089_1	1125863.JAFN01000001_gene3409	6.264e-18	91.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SRR25158527_k127_2554089_2	161156.JQKW01000007_gene716	3.542e-09	58.0	COG4775@1|root,COG4775@2|Bacteria,2GGVC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SRR25158527_k127_2557037_2	247490.KSU1_B0269	8.331e-16	78.0	COG3794@1|root,COG3794@2|Bacteria,2J06V@203682|Planctomycetes	203682|Planctomycetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3_3
SRR25158527_k127_2557037_1	1283283.ATXA01000021_gene2854	2.808e-30	129.0	COG0235@1|root,COG0235@2|Bacteria,2HGGU@201174|Actinobacteria,4EWNJ@85013|Frankiales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158527_k127_2557037_3	1123368.AUIS01000001_gene2026	3.939e-13	72.0	2E9MH@1|root,333U5@2|Bacteria,1NDRZ@1224|Proteobacteria,1STW7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2557037_0	926569.ANT_25190	1.373e-73	256.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158527_k127_2557576_2	504487.JCM19302_3951	0.0006879	45.0	COG0583@1|root,COG0583@2|Bacteria,4NGHS@976|Bacteroidetes,1HXYJ@117743|Flavobacteriia	976|Bacteroidetes	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158527_k127_2557576_1	926569.ANT_07480	3.072e-10	71.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_2557576_0	591158.SSMG_05758	1.683e-11	72.0	COG1840@1|root,COG1840@2|Bacteria,2I8D6@201174|Actinobacteria	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
SRR25158527_k127_2557997_3	880072.Desac_2413	4.141e-32	129.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria,2MR4U@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4921)	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
SRR25158527_k127_2557997_2	358396.C445_06995	3.902e-47	176.0	COG0293@1|root,COG3269@1|root,arCOG00079@2157|Archaea,arCOG01641@2157|Archaea,2XT12@28890|Euryarchaeota,23T6V@183963|Halobacteria	183963|Halobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rrmJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,TRAM
SRR25158527_k127_2557997_4	1380358.JADJ01000028_gene4087	1.243e-16	89.0	COG2885@1|root,COG2885@2|Bacteria,1RGHU@1224|Proteobacteria,1S5H8@1236|Gammaproteobacteria,1XR3B@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
SRR25158527_k127_2557997_1	748247.AZKH_2147	1.063e-54	202.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	dch	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158527_k127_2557997_0	497964.CfE428DRAFT_6357	1.813e-57	209.0	COG3176@1|root,COG3176@2|Bacteria,46UGN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
SRR25158527_k127_2560950_1	1499680.CCFE01000023_gene2581	2.147e-49	190.0	COG1960@1|root,COG1960@2|Bacteria,1UX6T@1239|Firmicutes,4IJKC@91061|Bacilli,1ZM73@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_2560950_0	463191.SSEG_01299	1.926e-77	273.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158527_k127_2560950_2	2074.JNYD01000003_gene4100	5.779e-07	57.0	COG3871@1|root,COG3871@2|Bacteria,2I2S9@201174|Actinobacteria,4E3EK@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158527_k127_256250_1	1123373.ATXI01000003_gene1306	1.166e-76	261.0	COG0040@1|root,COG0040@2|Bacteria,2GHDQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158527_k127_256250_0	273068.TTE1336	2.548e-168	549.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,42EY5@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Conserved carboxylase region	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158527_k127_256250_3	1131269.AQVV01000011_gene2496	5.238e-07	58.0	COG1245@1|root,COG1245@2|Bacteria	2|Bacteria	C	4Fe-4S binding domain	rnfB	-	1.8.99.2	ko:K00395,ko:K02572,ko:K03616	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FeS,Fer4,Fer4_4,Fer4_7
SRR25158527_k127_256250_2	1479238.JQMZ01000001_gene1445	2.615e-08	62.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,43ZW1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158527_k127_2566924_1	1247726.MIM_c20160	6.047e-22	102.0	COG1545@1|root,COG1545@2|Bacteria,1RB09@1224|Proteobacteria,2VV15@28216|Betaproteobacteria,3T952@506|Alcaligenaceae	28216|Betaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SRR25158527_k127_2566924_0	1437448.AZRT01000129_gene253	3.598e-87	301.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2TRHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2578248_0	246197.MXAN_2951	8.352e-40	154.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WQ7S@28221|Deltaproteobacteria,2YTZ9@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SRR25158527_k127_2578248_1	404589.Anae109_1534	1.382e-36	154.0	COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2582283_0	1131269.AQVV01000024_gene2368	3.361e-145	471.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
SRR25158527_k127_2582283_1	1111479.AXAR01000003_gene1669	0.0006363	46.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,279UX@186823|Alicyclobacillaceae	91061|Bacilli	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
SRR25158527_k127_2584318_0	246197.MXAN_1425	2.081e-103	343.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria,2YWZP@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158527_k127_2584318_1	1232410.KI421412_gene160	2.706e-37	143.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,43SM6@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158527_k127_2584318_2	264732.Moth_0731	5.398e-33	138.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,24AHX@186801|Clostridia,42FZR@68295|Thermoanaerobacterales	186801|Clostridia	S	Zn-dependent hydrolases of the	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158527_k127_2584318_3	246194.CHY_1135	5.19e-06	49.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,42GE8@68295|Thermoanaerobacterales	186801|Clostridia	P	Ferric uptake regulator, Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158527_k127_2584820_0	1095769.CAHF01000011_gene2298	9.747e-106	352.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,472ZS@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158527_k127_2584820_1	1276756.AUEX01000004_gene2372	2.648e-85	287.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AD31@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158527_k127_2586588_0	1123508.JH636448_gene7597	9.797e-08	64.0	2BR9S@1|root,32K89@2|Bacteria,2J2BP@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158527_k127_2589112_2	252305.OB2597_11501	1.109e-07	62.0	COG0697@1|root,COG0697@2|Bacteria,1R6SK@1224|Proteobacteria,2U4IR@28211|Alphaproteobacteria,2PE1N@252301|Oceanicola	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_2589112_0	439235.Dalk_4465	1.151e-77	272.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2MI2R@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SRR25158527_k127_2589112_1	1278073.MYSTI_07417	6.429e-51	190.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SRR25158527_k127_2596495_0	1123393.KB891326_gene41	2.859e-87	298.0	COG1376@1|root,COG1376@2|Bacteria,1MVI4@1224|Proteobacteria,2VKWG@28216|Betaproteobacteria,1KS3M@119069|Hydrogenophilales	119069|Hydrogenophilales	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
SRR25158527_k127_2596495_2	338963.Pcar_0380	4.455e-49	185.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,42U9S@68525|delta/epsilon subdivisions,2WQ1X@28221|Deltaproteobacteria,43SN2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF882)	ycbK	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
SRR25158527_k127_2596495_1	243233.MCA0498	4.421e-69	241.0	COG4094@1|root,COG4094@2|Bacteria,1RDV6@1224|Proteobacteria,1SAUX@1236|Gammaproteobacteria,1XGC9@135618|Methylococcales	135618|Methylococcales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
SRR25158527_k127_2599716_3	551275.KB899546_gene2266	1.699e-10	62.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,43XND@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158527_k127_2599716_0	443144.GM21_1887	5.154e-172	551.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,43TS7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158527_k127_2599716_2	1123226.KB899296_gene411	2.017e-25	107.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,26Z31@186822|Paenibacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
SRR25158527_k127_2599716_1	1121428.DESHY_70012___1	1.691e-75	259.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,260V1@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158527_k127_2602717_3	404589.Anae109_2746	3.234e-16	83.0	COG3005@1|root,COG3005@2|Bacteria,1Q9NJ@1224|Proteobacteria,434HC@68525|delta/epsilon subdivisions,2WYUP@28221|Deltaproteobacteria,2Z0NR@29|Myxococcales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
SRR25158527_k127_2602717_4	1379698.RBG1_1C00001G0770	1.923e-06	54.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
SRR25158527_k127_2602717_0	1379698.RBG1_1C00001G0780	3.531e-143	462.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
SRR25158527_k127_2602717_2	1379698.RBG1_1C00001G0781	6.007e-51	184.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
SRR25158527_k127_2602717_1	671143.DAMO_0822	2.234e-127	418.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
SRR25158527_k127_2609843_0	1267534.KB906760_gene1562	6.905e-56	218.0	COG3604@1|root,COG3829@1|root,COG3604@2|Bacteria,COG3829@2|Bacteria,3Y2V9@57723|Acidobacteria	57723|Acidobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,HTH_8,PAS_9,Sigma54_activat
SRR25158527_k127_2609843_1	211165.AJLN01000048_gene6000	2.62e-43	179.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JKNQ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158527_k127_2610054_2	1123242.JH636435_gene1758	2.782e-58	209.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_16815	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
SRR25158527_k127_2610054_1	706587.Desti_1031	1.222e-134	441.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585,ko:K07799	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00646,M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1,8.A.1.6	-	-	HlyD_D23
SRR25158527_k127_2610054_0	706587.Desti_1032	0.0	1254.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158527_k127_2612856_0	330214.NIDE2238	8.892e-302	940.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SRR25158527_k127_2615654_0	645991.Sgly_0956	2.434e-37	149.0	COG0637@1|root,COG0637@2|Bacteria,1UW2W@1239|Firmicutes,25M3W@186801|Clostridia,2664X@186807|Peptococcaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158527_k127_2615654_1	497965.Cyan7822_0316	3.854e-06	55.0	COG3678@1|root,COG3678@2|Bacteria,1G95S@1117|Cyanobacteria,3KIFE@43988|Cyanothece	1117|Cyanobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
SRR25158527_k127_2616455_1	1382306.JNIM01000001_gene3262	7.942e-09	59.0	COG0654@1|root,COG0654@2|Bacteria,2G66I@200795|Chloroflexi	200795|Chloroflexi	C	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158527_k127_2616455_0	316055.RPE_3841	2.02e-114	382.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TRA4@28211|Alphaproteobacteria,3JSPN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_2616455_2	420324.KI912069_gene6363	3.745e-05	46.0	COG0583@1|root,COG0583@2|Bacteria,1R51E@1224|Proteobacteria,2TZIK@28211|Alphaproteobacteria,1JXVG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158527_k127_2621518_0	671143.DAMO_0621	0.0	1400.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
SRR25158527_k127_2621518_1	1038859.AXAU01000003_gene5873	7.473e-91	310.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,3JXHZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_2625403_0	247490.KSU1_D0350	1.505e-33	149.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2626636_0	1051632.TPY_3721	1.737e-192	625.0	COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes	1239|Firmicutes	E	Aminopeptidase	pepN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
SRR25158527_k127_2635498_0	1120949.KB903314_gene302	3.314e-112	380.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1,SBP_bac_6
SRR25158527_k127_2635498_1	1120949.KB903314_gene301	6.846e-104	348.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	potA	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158527_k127_2635498_2	1120949.KB903314_gene307	9.67e-58	210.0	COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria,4D9VJ@85008|Micromonosporales	201174|Actinobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158527_k127_2644759_2	443152.MDG893_15387	9.077e-34	135.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,1RQPW@1236|Gammaproteobacteria,469ZW@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
SRR25158527_k127_2644759_1	443152.MDG893_15467	2.544e-52	198.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2644759_3	1173024.KI912154_gene865	5.351e-27	113.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,1JHXE@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158527_k127_2644759_0	643473.KB235930_gene2822	1.824e-54	192.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,1HMNK@1161|Nostocales	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158527_k127_2648907_2	1122138.AQUZ01000027_gene820	8.421e-08	55.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_2648907_0	1122138.AQUZ01000027_gene820	2.498e-33	144.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_2648907_1	266117.Rxyl_2097	1.463e-16	86.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CPC0@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_2651714_0	331678.Cphamn1_2068	4.434e-164	522.0	COG0372@1|root,COG0372@2|Bacteria,1FD5Z@1090|Chlorobi	1090|Chlorobi	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158527_k127_2651714_2	671143.DAMO_0142	5.899e-25	110.0	COG2062@1|root,COG2062@2|Bacteria,2NRKX@2323|unclassified Bacteria	2|Bacteria	T	Histidine phosphatase superfamily (branch 1)	sixA	-	3.6.1.55	ko:K03574,ko:K08296	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1
SRR25158527_k127_2651714_1	207559.Dde_2763	1.479e-70	242.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria,2M7ZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K10038	ko02010,map02010	M00227,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.2	-	-	ABC_tran
SRR25158527_k127_2656734_0	1340493.JNIF01000003_gene1826	1.074e-30	139.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Phosphodiest
SRR25158527_k127_26637_1	485913.Krac_5131	9.472e-66	227.0	COG2059@1|root,COG2059@2|Bacteria,2G6NB@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158527_k127_26637_2	1207063.P24_10490	3.905e-20	95.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2JS47@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_26637_0	1123392.AQWL01000010_gene2312	2.441e-83	282.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,2WGR7@28216|Betaproteobacteria,1KSBE@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_2669882_2	1906.SFRA_15780	7.809e-79	268.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2669882_0	671143.DAMO_1993	1.649e-289	900.0	COG1053@1|root,COG1053@2|Bacteria,2NNR9@2323|unclassified Bacteria	2|Bacteria	C	succinate dehydrogenase, flavoprotein subunit	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158527_k127_2669882_1	1048339.KB913029_gene69	2.211e-101	332.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4ERFH@85013|Frankiales	201174|Actinobacteria	C	Succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRR25158527_k127_2684200_1	3218.PP1S46_300V6.1	1.329e-76	270.0	COG0667@1|root,2S0PI@2759|Eukaryota,37UGN@33090|Viridiplantae,3GP0T@35493|Streptophyta	35493|Streptophyta	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158527_k127_2684200_2	1246484.D479_15597	8.379e-12	72.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,4HGZN@91061|Bacilli,3NF1M@45667|Halobacillus	91061|Bacilli	S	TQO small subunit DoxD	M1-1022	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158527_k127_2684200_0	321332.CYB_0151	2.184e-79	272.0	COG0491@1|root,COG0491@2|Bacteria,1G04I@1117|Cyanobacteria,1GYPD@1129|Synechococcus	1117|Cyanobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
SRR25158527_k127_2691872_2	675635.Psed_4311	3.866e-17	83.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4E3ZP@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158527_k127_2691872_0	1134413.ANNK01000086_gene318	3.203e-118	389.0	COG0715@1|root,COG0715@2|Bacteria,1TXP3@1239|Firmicutes,4I6PJ@91061|Bacilli,1ZM9Z@1386|Bacillus	91061|Bacilli	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_2691872_3	1304888.ATWF01000001_gene1123	2.463e-08	58.0	COG2331@1|root,COG2331@2|Bacteria,2GG63@200930|Deferribacteres	200930|Deferribacteres	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158527_k127_2691872_1	56780.SYN_02371	5.771e-71	247.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2MQ94@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158527_k127_2693700_0	479434.Sthe_3255	1.52e-78	268.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,27XWA@189775|Thermomicrobia	200795|Chloroflexi	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158527_k127_2693700_3	1173263.Syn7502_03004	6.64e-45	175.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_2693700_1	1243664.CAVL020000045_gene2107	3.706e-68	241.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158527_k127_2693700_2	1231391.AMZF01000003_gene3115	5.185e-49	177.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2W95G@28216|Betaproteobacteria,3T7RQ@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158527_k127_2695008_1	1379698.RBG1_1C00001G1513	6.938e-25	111.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SRR25158527_k127_2695008_3	1232437.KL662023_gene905	1.171e-21	97.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2MM3G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158527_k127_2695008_0	1380394.JADL01000004_gene5909	1.101e-93	315.0	COG0346@1|root,COG0346@2|Bacteria,1MX75@1224|Proteobacteria,2TRQS@28211|Alphaproteobacteria,2JVNN@204441|Rhodospirillales	204441|Rhodospirillales	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2695008_2	63737.Npun_R2437	5.162e-23	101.0	COG0451@1|root,COG0451@2|Bacteria,1G0GJ@1117|Cyanobacteria,1HIYE@1161|Nostocales	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158527_k127_2700561_1	448385.sce1656	3.072e-30	125.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria,2YYCH@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158527_k127_2700561_3	345341.KUTG_04140	4.491e-06	55.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2700561_0	644282.Deba_1407	4.668e-39	149.0	COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Ribonuclease H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SRR25158527_k127_2700561_2	1123371.ATXH01000020_gene478	5.248e-27	119.0	COG1579@1|root,COG1579@2|Bacteria,2GH3N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SRR25158527_k127_2703909_1	1123234.AUKI01000011_gene1494	2.927e-21	101.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,1HWTQ@117743|Flavobacteriia	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
SRR25158527_k127_2703909_0	1128421.JAGA01000004_gene2558	4.681e-123	409.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_2705335_0	1125863.JAFN01000001_gene40	1.425e-41	157.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
SRR25158527_k127_2705335_2	1340493.JNIF01000004_gene722	7.427e-17	81.0	COG0333@1|root,COG0333@2|Bacteria,3Y5W0@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158527_k127_2705335_1	398767.Glov_1942	8.645e-26	113.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158527_k127_2717756_1	1038860.AXAP01000097_gene5007	3.236e-17	88.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_2717756_2	1157708.KB907451_gene4898	3.476e-06	55.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,4ACMC@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	yiaD_1	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
SRR25158527_k127_2717756_0	710686.Mycsm_01832	7.135e-44	173.0	COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria	201174|Actinobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
SRR25158527_k127_2718486_1	197221.22293934	9.939e-39	149.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158527_k127_2718486_0	1128421.JAGA01000003_gene3195	1.038e-55	211.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
SRR25158527_k127_2718486_2	933262.AXAM01000028_gene3312	4.699e-09	59.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2MHXQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158527_k127_2720392_2	756272.Plabr_0133	0.0004608	48.0	COG0457@1|root,COG0500@1|root,COG0859@1|root,COG1215@1|root,COG0457@2|Bacteria,COG0500@2|Bacteria,COG0859@2|Bacteria,COG1215@2|Bacteria,2IYBQ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SRR25158527_k127_2720392_0	237368.SCABRO_00411	5.564e-75	262.0	COG0345@1|root,COG0345@2|Bacteria,2IY5U@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
SRR25158527_k127_2720422_0	935948.KE386494_gene372	3.686e-59	220.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,42FE6@68295|Thermoanaerobacterales	186801|Clostridia	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158527_k127_2720422_1	742735.HMPREF9467_04281	6.419e-14	75.0	28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia,21XEK@1506553|Lachnoclostridium	186801|Clostridia	C	COG NOG06476 non supervised orthologous group	grdE	-	1.21.4.2	ko:K10671	-	-	-	-	ko00000,ko01000	-	-	-	Gly_reductase
SRR25158527_k127_2729907_0	237368.SCABRO_01504	3.387e-142	460.0	COG0659@1|root,COG0659@2|Bacteria,2IX8K@203682|Planctomycetes	203682|Planctomycetes	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
SRR25158527_k127_2729907_1	1463825.JNXC01000002_gene4640	3.6e-21	96.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4DXWW@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158527_k127_2730263_1	358220.C380_16430	1.206e-103	346.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,4AAYT@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
SRR25158527_k127_2730263_2	1151127.KB906325_gene5005	3.087e-24	109.0	2C1K4@1|root,30F52@2|Bacteria,1REDQ@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
SRR25158527_k127_2730263_0	420324.KI911961_gene1687	4.322e-218	687.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	MA20_15045	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
SRR25158527_k127_274287_1	1177594.MIC448_870001	5.054e-52	189.0	COG0252@1|root,COG0252@2|Bacteria,2H4TM@201174|Actinobacteria	201174|Actinobacteria	EJ	asparaginase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_274287_0	397278.JOJN01000005_gene773	3.158e-84	292.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria,4DUY9@85009|Propionibacteriales	201174|Actinobacteria	S	Nitrile hydratase, alpha chain	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
SRR25158527_k127_2746917_1	1082705.JIBP01000017_gene664	0.0003182	51.0	COG1052@1|root,COG1052@2|Bacteria,1QVZS@1224|Proteobacteria,1T33S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158527_k127_2746917_0	886293.Sinac_7530	2.041e-87	298.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158527_k127_2754270_0	1446473.JHWH01000006_gene1832	7.744e-269	835.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2PW79@265|Paracoccus	28211|Alphaproteobacteria	I	functions in conversion of succinate to propionate	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
SRR25158527_k127_2754270_1	1207063.P24_03525	0.0005298	45.0	COG3064@1|root,COG3064@2|Bacteria,1NAWA@1224|Proteobacteria,2TSQY@28211|Alphaproteobacteria,2JTC2@204441|Rhodospirillales	204441|Rhodospirillales	M	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SRR25158527_k127_2758247_0	1449063.JMLS01000027_gene61	1.275e-23	110.0	COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_2758247_1	1382304.JNIL01000001_gene1318	4.218e-07	60.0	COG0715@1|root,COG0715@2|Bacteria,1UZYY@1239|Firmicutes,4HE24@91061|Bacilli	91061|Bacilli	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_275998_2	269799.Gmet_0784	1.446e-20	97.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria,43USX@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaC protein	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR25158527_k127_275998_1	1121403.AUCV01000017_gene4487	1.294e-28	119.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,42TIU@68525|delta/epsilon subdivisions,2WT5E@28221|Deltaproteobacteria,2MNUC@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Prokaryotic diacylglycerol kinase	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
SRR25158527_k127_275998_0	479434.Sthe_3181	6.498e-89	315.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_2760693_1	685778.AORL01000021_gene700	5.35e-07	60.0	COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria,2U32D@28211|Alphaproteobacteria,2K2T6@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158527_k127_2760693_0	1123288.SOV_3c02660	2.258e-44	169.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4H3JV@909932|Negativicutes	909932|Negativicutes	KT	response regulator, receiver	narL	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158527_k127_2761513_1	710686.Mycsm_06052	1.476e-08	67.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23D5F@1762|Mycobacteriaceae	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_2761513_0	118163.Ple7327_1614	7.082e-56	205.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,3VKKA@52604|Pleurocapsales	1117|Cyanobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_2765115_3	1173022.Cri9333_4038	1.919e-10	64.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	ladS	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315,ko:K20971	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GAF,HATPase_c,HisKA,Response_reg,TPR_12,TPR_8
SRR25158527_k127_2765115_0	1192034.CAP_6251	4.313e-61	224.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_2765115_4	546266.NEIMUCOT_04907	7.489e-06	54.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,2KPP5@206351|Neisseriales	206351|Neisseriales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158527_k127_2765115_2	717605.Theco_0007	6.671e-32	127.0	COG0640@1|root,COG0640@2|Bacteria,1V6CU@1239|Firmicutes,4HJ7N@91061|Bacilli,26YN7@186822|Paenibacillaceae	91061|Bacilli	K	ArsR family transcriptional regulator	arsR9	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158527_k127_2765115_1	671143.DAMO_2827	1.252e-53	192.0	COG3260@1|root,COG3260@2|Bacteria,2NRM4@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hycG	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
SRR25158527_k127_2766074_1	391595.RLO149_c008070	8.604e-44	165.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,2TRJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912,ko:K20333	ko00340,ko02024,map00340,map02024	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
SRR25158527_k127_2766074_0	402777.KB235903_gene1332	2.493e-48	182.0	COG1279@1|root,COG1279@2|Bacteria,1GQJ3@1117|Cyanobacteria,1HHX6@1150|Oscillatoriales	1117|Cyanobacteria	S	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158527_k127_2766074_2	1206735.BAGG01000110_gene4710	1.439e-22	109.0	COG3239@1|root,COG3239@2|Bacteria,2I8NB@201174|Actinobacteria,4G0AE@85025|Nocardiaceae	201174|Actinobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158527_k127_2767597_2	926559.JoomaDRAFT_2224	2.41e-09	59.0	2DMPS@1|root,32SXU@2|Bacteria,4NTIT@976|Bacteroidetes,1I41A@117743|Flavobacteriia	976|Bacteroidetes	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158527_k127_2767597_0	243231.GSU0652	2.171e-115	377.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,43VVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SRR25158527_k127_2767597_1	671143.DAMO_2425	4.092e-39	151.0	COG0388@1|root,COG0388@2|Bacteria,2NQD8@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
SRR25158527_k127_2768719_0	1232410.KI421426_gene1428	8.848e-105	353.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria,43SA6@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA
SRR25158527_k127_2774585_1	316057.RPD_4078	8.662e-55	194.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2TWC9@28211|Alphaproteobacteria,3JVP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158527_k127_2774585_0	443152.MDG893_15295	2.208e-60	222.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_277610_0	909663.KI867149_gene3370	2.816e-124	416.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158527_k127_2788392_0	264198.Reut_B5778	2.298e-50	189.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1K2TY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2788392_1	1118054.CAGW01000075_gene3261	1.342e-11	74.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_2794793_1	1121423.JONT01000015_gene1305	8.529e-05	48.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,26259@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158527_k127_2794793_0	56780.SYN_00558	5.532e-181	577.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MQAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SRR25158527_k127_2800669_1	1267533.KB906741_gene405	5.427e-80	272.0	COG4638@1|root,COG4638@2|Bacteria,3Y547@57723|Acidobacteria,2JNCI@204432|Acidobacteriia	204432|Acidobacteriia	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158527_k127_2800669_0	1449049.JONW01000009_gene4562	1.371e-90	308.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2KFA4@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
SRR25158527_k127_2800669_2	1463909.KL585949_gene6527	4.609e-09	66.0	COG0477@1|root,COG2814@2|Bacteria,2GK86@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_2802283_1	96561.Dole_3214	0.0001904	53.0	COG3087@1|root,COG3087@2|Bacteria,1MZ8M@1224|Proteobacteria,42UXP@68525|delta/epsilon subdivisions,2WQRZ@28221|Deltaproteobacteria,2MKIK@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
SRR25158527_k127_2802283_0	562970.Btus_1633	4.215e-53	200.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli	91061|Bacilli	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_2810203_0	1286093.C266_18966	2.504e-103	343.0	COG4177@1|root,COG4177@2|Bacteria,1R91I@1224|Proteobacteria,2VIIS@28216|Betaproteobacteria,1K6A4@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158527_k127_2810203_3	640081.Dsui_2058	3.751e-90	305.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,2KVIX@206389|Rhodocyclales	28216|Betaproteobacteria	E	branched-chain amino acid	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158527_k127_2810203_2	1286093.C266_18956	3.207e-91	306.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VIV4@28216|Betaproteobacteria,1K6FT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	abc transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158527_k127_2810203_4	290397.Adeh_1001	3.845e-09	63.0	COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,42NF7@68525|delta/epsilon subdivisions,2WJA9@28221|Deltaproteobacteria,2YW0W@29|Myxococcales	28221|Deltaproteobacteria	L	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,PBP_like
SRR25158527_k127_2810203_1	1120983.KB894572_gene3272	4.791e-98	333.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria,1JQ4A@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158527_k127_2816724_1	1184609.KILIM_005_00530	1.311e-10	66.0	COG2197@1|root,COG2197@2|Bacteria,2GMUG@201174|Actinobacteria	201174|Actinobacteria	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158527_k127_2816724_0	85643.Tmz1t_4020	2.175e-99	341.0	COG0657@1|root,COG0657@2|Bacteria,1MV89@1224|Proteobacteria,2VJJC@28216|Betaproteobacteria,2M03F@206389|Rhodocyclales	206389|Rhodocyclales	I	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
SRR25158527_k127_2827879_1	1031711.RSPO_c00910	1.142e-07	59.0	COG4715@1|root,COG4715@2|Bacteria,1R60K@1224|Proteobacteria,2WBKW@28216|Betaproteobacteria,1K68R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Zinc finger, swim domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
SRR25158527_k127_2827879_0	1192034.CAP_6251	6.71e-41	163.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_2830098_0	1231391.AMZF01000110_gene916	8.034e-235	739.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_2830634_1	402881.Plav_1099	1.297e-41	161.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TUFK@28211|Alphaproteobacteria,1JQJS@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
SRR25158527_k127_2830634_0	686340.Metal_1824	8.874e-133	431.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1XEX2@135618|Methylococcales	135618|Methylococcales	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K05685	ko02010,map02010	M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
SRR25158527_k127_2831407_2	1297617.JPJD01000022_gene1712	1.526e-05	54.0	COG2186@1|root,COG2186@2|Bacteria,1V0HM@1239|Firmicutes,24PT6@186801|Clostridia,26CNT@186813|unclassified Clostridiales	186801|Clostridia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158527_k127_2831407_1	411684.HPDFL43_11596	5.676e-91	312.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,43Q8S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
SRR25158527_k127_2831407_0	420324.KI912061_gene6190	7.62e-118	391.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,1JZHH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158527_k127_2833109_0	398767.Glov_1255	7.863e-15	85.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,43S55@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SRR25158527_k127_2834871_0	1128421.JAGA01000004_gene2558	1.849e-110	371.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_2834871_1	1134474.O59_004232	1.816e-05	55.0	COG3577@1|root,COG3577@2|Bacteria,1N8CA@1224|Proteobacteria,1RSA4@1236|Gammaproteobacteria,1FGI5@10|Cellvibrio	1236|Gammaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,TPR_19,gag-asp_proteas
SRR25158527_k127_2835956_1	1144305.PMI02_00880	6.28e-10	68.0	COG3473@1|root,COG3473@2|Bacteria,1RKZQ@1224|Proteobacteria,2U13U@28211|Alphaproteobacteria,2K85M@204457|Sphingomonadales	204457|Sphingomonadales	Q	Maleate cis-trans isomerase	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158527_k127_2835956_0	266779.Meso_2926	1.348e-126	421.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,43KZ3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_2836843_2	247490.KSU1_C0935	1.644e-31	126.0	COG0450@1|root,COG0450@2|Bacteria,2IZ3M@203682|Planctomycetes	203682|Planctomycetes	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158527_k127_2836843_3	671143.DAMO_1602	1.747e-20	100.0	COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	MA20_19235	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
SRR25158527_k127_2836843_0	324925.Ppha_1319	3.635e-152	493.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_2836843_1	1379698.RBG1_1C00001G1238	8.593e-55	204.0	COG5000@1|root,COG5000@2|Bacteria,2NQEP@2323|unclassified Bacteria	2|Bacteria	T	COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1
SRR25158527_k127_2838264_1	69279.BG36_07140	4.563e-08	59.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2V7D9@28211|Alphaproteobacteria,43KPE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
SRR25158527_k127_2838264_0	1532558.JL39_06940	1.784e-25	121.0	COG1840@1|root,COG1840@2|Bacteria,1PGNJ@1224|Proteobacteria,2V7JA@28211|Alphaproteobacteria,4BDDZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158527_k127_2840752_0	1429916.X566_14165	2.455e-104	345.0	COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2TU75@28211|Alphaproteobacteria,3JTKI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SRR25158527_k127_2840752_1	103733.JNYO01000005_gene8566	1.255e-29	126.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4E426@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
SRR25158527_k127_2845647_0	1303518.CCALI_01952	5.765e-36	147.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_2845647_1	298653.Franean1_3124	2.833e-06	58.0	COG0715@1|root,COG0715@2|Bacteria,2IGX1@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_2852484_0	1173028.ANKO01000041_gene3223	2.223e-119	387.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,1H8CN@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
SRR25158527_k127_2855450_2	525904.Tter_1099	1.842e-16	91.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2855450_1	289376.THEYE_A1398	5.423e-41	160.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,3J0PD@40117|Nitrospirae	40117|Nitrospirae	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
SRR25158527_k127_2855450_0	1265505.ATUG01000001_gene4320	3.7e-88	295.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158527_k127_2868077_3	243231.GSU2568	9.418e-42	158.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,43TX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
SRR25158527_k127_2868077_1	316067.Geob_1979	5.842e-103	345.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SRR25158527_k127_2868077_2	1232410.KI421413_gene846	6.44e-76	262.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,43S76@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Serine acetyltransferase, N-terminal	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SRR25158527_k127_2868077_0	639282.DEFDS_1179	3.395e-131	426.0	COG0119@1|root,COG0119@2|Bacteria,2GF1G@200930|Deferribacteres	200930|Deferribacteres	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158527_k127_2873757_2	1499967.BAYZ01000139_gene140	5.205e-67	236.0	COG1680@1|root,COG1680@2|Bacteria,2NPA1@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158527_k127_2873757_1	765869.BDW_07030	1.071e-133	441.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2MSVI@213481|Bdellovibrionales,2WJ8S@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Mur ligase, middle domain	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158527_k127_2873757_5	1121918.ARWE01000001_gene235	8.843e-07	53.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	tmoA	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494	1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1	ko:K00688,ko:K15760,ko:K16157,ko:K16242,ko:K18223,ko:K22353,ko:K22357	ko00361,ko00362,ko00500,ko00623,ko00625,ko00640,ko00680,ko01100,ko01110,ko01120,ko01200,ko01220,ko02026,ko04217,ko04910,ko04922,ko04931,map00361,map00362,map00500,map00623,map00625,map00640,map00680,map01100,map01110,map01120,map01200,map01220,map02026,map04217,map04910,map04922,map04931	M00174,M00538,M00548	R01142,R02111,R02550,R03560,R03562,R03608,R05444,R05666,R10042,R10043,R10702,R11901	RC00046,RC00173,RC00269,RC00490,RC01383,RC03249	ko00000,ko00001,ko00002,ko01000	-	GT35	-	Phenol_Hydrox,YHS
SRR25158527_k127_2873757_3	1131269.AQVV01000045_gene1583	1.146e-37	151.0	COG0801@1|root,COG0801@2|Bacteria	2|Bacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0041	FolB,HPPK
SRR25158527_k127_2873757_0	330214.NIDE0503	7.423e-164	523.0	COG0436@1|root,COG0436@2|Bacteria,3J0G2@40117|Nitrospirae	40117|Nitrospirae	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158527_k127_2873757_4	56780.SYN_01764	1.388e-23	105.0	COG3688@1|root,COG3688@2|Bacteria,1N1NF@1224|Proteobacteria,42UMH@68525|delta/epsilon subdivisions,2WQJ5@28221|Deltaproteobacteria,2MSA5@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
SRR25158527_k127_2885326_0	1217718.ALOU01000009_gene1072	9.547e-113	376.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VN32@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_2885326_1	1211115.ALIQ01000238_gene3256	7.468e-90	303.0	COG2242@1|root,COG2242@2|Bacteria,1R0I9@1224|Proteobacteria,2TZR6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_2885326_2	1392838.AWNM01000018_gene3438	5.533e-42	158.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2WGJ7@28216|Betaproteobacteria,3T9HQ@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
SRR25158527_k127_289158_2	1231391.AMZF01000020_gene1928	0.00055	46.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_289158_0	479434.Sthe_2909	2.03e-143	471.0	COG1012@1|root,COG1012@2|Bacteria,2G7YU@200795|Chloroflexi,27Y0H@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158527_k127_289158_1	1121859.KB890755_gene1122	2.803e-09	59.0	COG0657@1|root,COG0657@2|Bacteria,4NJ8D@976|Bacteroidetes	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH,Lipase_GDSL_2,Peptidase_S9
SRR25158527_k127_2894005_4	1340493.JNIF01000004_gene1203	1.379e-20	98.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SRR25158527_k127_2894005_3	234267.Acid_1416	5.455e-30	130.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C
SRR25158527_k127_2894005_1	330214.NIDE3388	4.262e-54	198.0	COG1208@1|root,COG1208@2|Bacteria,3J0QW@40117|Nitrospirae	40117|Nitrospirae	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158527_k127_2894005_0	330214.NIDE3389	2.801e-60	223.0	COG3178@1|root,COG3178@2|Bacteria,3J15Y@40117|Nitrospirae	40117|Nitrospirae	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158527_k127_2894005_5	370438.PTH_1606	2.534e-12	68.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SRR25158527_k127_2894005_2	269799.Gmet_2863	4.626e-53	190.0	COG0388@1|root,COG0388@2|Bacteria,1RIQI@1224|Proteobacteria,42T6J@68525|delta/epsilon subdivisions,2WPVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158527_k127_2894756_0	1206731.BAGB01000047_gene5200	8.382e-46	180.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4FXFM@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_2894756_1	716928.AJQT01000123_gene285	1.835e-16	91.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,4BBDJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_2896658_1	1291050.JAGE01000001_gene932	4.001e-49	188.0	COG2865@1|root,COG2865@2|Bacteria,1TQIP@1239|Firmicutes,24CJ9@186801|Clostridia,3WRQ1@541000|Ruminococcaceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
SRR25158527_k127_2896658_0	330214.NIDE3307	5.375e-54	202.0	COG2813@1|root,COG2813@2|Bacteria	2|Bacteria	J	rRNA (guanine-N2-)-methyltransferase activity	crtF	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.210,2.1.1.304,2.1.1.333	ko:K09846,ko:K13604,ko:K21460	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	-	R07521,R07524,R07527,R07529,R07533,R07535,R09063	RC00003,RC01662,RC02082	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
SRR25158527_k127_2896658_3	398512.JQKC01000018_gene2924	1.719e-09	63.0	COG1251@1|root,COG1251@2|Bacteria,1VKDD@1239|Firmicutes	1239|Firmicutes	C	2Fe-2S -binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
SRR25158527_k127_2900518_1	234267.Acid_5563	4.92e-98	330.0	COG5267@1|root,COG5267@2|Bacteria,3Y342@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
SRR25158527_k127_2900518_0	234267.Acid_5562	1.387e-125	420.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158527_k127_290885_0	558169.AGAV01000018_gene3535	1.374e-123	409.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli	91061|Bacilli	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158527_k127_290885_1	948106.AWZT01000001_gene5091	5.993e-18	87.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2W1P1@28216|Betaproteobacteria,1K0XN@119060|Burkholderiaceae	28216|Betaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_2908959_0	472759.Nhal_0669	3.269e-191	610.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,1RPU2@1236|Gammaproteobacteria,1WWU8@135613|Chromatiales	135613|Chromatiales	S	SpoVR family	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
SRR25158527_k127_2908959_1	1473546.CH76_06790	4.296e-32	132.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3IW2H@400634|Lysinibacillus	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SRR25158527_k127_2916954_6	632335.Calkr_1751	7.211e-06	52.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42GX3@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SRR25158527_k127_2916954_5	644282.Deba_2930	8.634e-09	58.0	COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SRR25158527_k127_2916954_2	1267535.KB906767_gene2697	1.73e-56	200.0	COG0197@1|root,COG0197@2|Bacteria,3Y4EG@57723|Acidobacteria	57723|Acidobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158527_k127_2916954_0	1232410.KI421428_gene1236	1.952e-100	331.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,43T5Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158527_k127_2916954_4	1121413.JMKT01000010_gene963	2.749e-35	141.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria,2MBW5@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158527_k127_2916954_3	1167006.UWK_02051	5.989e-39	147.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2MKPD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158527_k127_2916954_1	309803.CTN_0996	7.362e-98	325.0	COG0090@1|root,COG0090@2|Bacteria,2GBXA@200918|Thermotogae	200918|Thermotogae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158527_k127_2917335_0	1041159.AZUW01000018_gene770	9.327e-157	503.0	COG4106@1|root,COG4106@2|Bacteria,1QVHH@1224|Proteobacteria,2TXG5@28211|Alphaproteobacteria,4BNYB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_2917335_1	1353531.AZNX01000008_gene774	1.063e-92	312.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2U1C5@28211|Alphaproteobacteria,4BC24@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
SRR25158527_k127_2922045_0	525904.Tter_0334	1.049e-138	454.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158527_k127_2922045_1	1122222.AXWR01000014_gene1280	2.072e-05	49.0	COG1013@1|root,COG1013@2|Bacteria,1WIGM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
SRR25158527_k127_2923172_0	450851.PHZ_c2593	1.515e-53	194.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2KGAN@204458|Caulobacterales	204458|Caulobacterales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158527_k127_2923172_1	335541.Swol_1724	4.554e-13	83.0	COG5426@1|root,COG5426@2|Bacteria,1UJJE@1239|Firmicutes,25F4H@186801|Clostridia	186801|Clostridia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2925225_1	768679.TTX_0776	1.11e-30	131.0	COG0467@1|root,arCOG01171@2157|Archaea,2XSQ7@28889|Crenarchaeota	28889|Crenarchaeota	T	Rad51	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158527_k127_2925225_0	1365176.N186_03460	9.925e-32	134.0	COG0467@1|root,arCOG01171@2157|Archaea,2XRYI@28889|Crenarchaeota	28889|Crenarchaeota	T	Circadian clock protein KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SRR25158527_k127_2927477_0	316067.Geob_3632	0.0	1588.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,43T41@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158527_k127_2927477_4	1123325.JHUV01000003_gene1576	3.418e-43	160.0	COG0222@1|root,COG0222@2|Bacteria,2G42K@200783|Aquificae	200783|Aquificae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158527_k127_2927477_5	96561.Dole_0700	8.96e-29	123.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2WQE8@28221|Deltaproteobacteria,2MKCS@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158527_k127_2927477_1	521098.Aaci_2723	2.421e-93	313.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,278Y0@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158527_k127_2927477_3	1121456.ATVA01000011_gene1609	5.633e-60	210.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2WNAH@28221|Deltaproteobacteria,2MB3K@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158527_k127_2927477_2	338963.Pcar_0689	1.077e-79	269.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,43S5Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SRR25158527_k127_2927477_6	880072.Desac_1469	5.386e-08	58.0	COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MSHF@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158527_k127_2935298_3	1366050.N234_12150	6.856e-10	66.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K11210	-	-	-	-	ko00000,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_2935298_0	443152.MDG893_15295	1.763e-54	204.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2935298_1	443152.MDG893_15295	8.117e-52	196.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2935298_2	443152.MDG893_15295	5.749e-23	102.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_2941174_1	570967.JMLV01000009_gene989	1.488e-16	87.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2UFDN@28211|Alphaproteobacteria,2JTWK@204441|Rhodospirillales	204441|Rhodospirillales	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158527_k127_2941174_0	1356854.N007_12390	4.744e-51	188.0	COG0483@1|root,COG0483@2|Bacteria,1UKWB@1239|Firmicutes,4ITKN@91061|Bacilli	91061|Bacilli	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158527_k127_2943314_1	247490.KSU1_B0566	2.141e-26	112.0	COG2204@1|root,COG2204@2|Bacteria,2J2AC@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
SRR25158527_k127_2943314_0	330214.NIDE2219	1.185e-93	311.0	COG3497@1|root,COG3497@2|Bacteria	2|Bacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
SRR25158527_k127_2952368_6	517418.Ctha_0772	4.388e-25	106.0	COG2839@1|root,COG2839@2|Bacteria,1FE53@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
SRR25158527_k127_2952368_4	1403819.BATR01000164_gene5635	3.061e-52	187.0	COG0662@1|root,COG0662@2|Bacteria,46W1W@74201|Verrucomicrobia,2IW0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2952368_3	32049.SYNPCC7002_A0337	2.057e-56	203.0	COG0346@1|root,COG0346@2|Bacteria,1G504@1117|Cyanobacteria,1H0G4@1129|Synechococcus	1117|Cyanobacteria	E	Lactoylglutathione lyase	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_2952368_1	1385519.N801_18235	2.836e-98	332.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,4FJQG@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320,ko:K14728	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158527_k127_2952368_0	1194972.MVAC_25200	3.941e-127	417.0	COG0402@1|root,COG0402@2|Bacteria,2IBR8@201174|Actinobacteria,2372F@1762|Mycobacteriaceae	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.2.18	ko:K15358	ko00760,ko01120,map00760,map01120	-	R07984	RC01933	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158527_k127_2952368_2	247490.KSU1_D0785	5.868e-57	218.0	COG1108@1|root,COG1108@2|Bacteria	2|Bacteria	P	ABC-type Mn2 Zn2 transport systems permease components	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158527_k127_2952368_5	1123320.KB889691_gene377	8.659e-45	171.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	yfeB	-	-	ko:K02074,ko:K09820,ko:K11710	ko02010,map02010	M00243,M00244,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR25158527_k127_2975975_1	591158.SSMG_05758	3.197e-15	86.0	COG1840@1|root,COG1840@2|Bacteria,2I8D6@201174|Actinobacteria	201174|Actinobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
SRR25158527_k127_2975975_0	627192.SLG_34970	5.05e-111	368.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske (2Fe-2S) domain-containing protein	-	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
SRR25158527_k127_2983960_0	1183438.GKIL_3640	4.512e-209	664.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1GBPU@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158527_k127_2983960_1	266265.Bxe_A1116	1.328e-31	135.0	COG0715@1|root,COG0715@2|Bacteria,1Q068@1224|Proteobacteria,2WAND@28216|Betaproteobacteria,1K3PC@119060|Burkholderiaceae	28216|Betaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2983960_2	359.CN09_33115	1.37e-10	72.0	COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2U6AN@28211|Alphaproteobacteria,4BM26@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,NMT1_2
SRR25158527_k127_2985823_0	1403819.BATR01000093_gene2905	6.455e-100	332.0	COG3239@1|root,COG3239@2|Bacteria,46SX7@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid desaturase	desA	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
SRR25158527_k127_2985823_1	644966.Tmar_0753	1.336e-09	62.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,24GH5@186801|Clostridia,3WDHK@538999|Clostridiales incertae sedis	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158527_k127_2988212_0	1210884.HG799468_gene13775	2.941e-60	222.0	2EPSC@1|root,33HCV@2|Bacteria,2J2Q4@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158527_k127_2988212_1	497964.CfE428DRAFT_2465	9.119e-09	59.0	291HJ@1|root,2ZP44@2|Bacteria,46WS5@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2993174_4	391593.RCCS2_09354	1.661e-06	55.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,2TR1X@28211|Alphaproteobacteria,2P21P@2433|Roseobacter	28211|Alphaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
SRR25158527_k127_2993174_2	1116472.MGMO_53c00580	1.782e-37	147.0	COG0597@1|root,COG0597@2|Bacteria,1N9NS@1224|Proteobacteria,1SPRT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158527_k127_2993174_3	397945.Aave_4648	4.48e-10	68.0	2DPZY@1|root,3345E@2|Bacteria,1NC0H@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_2993174_0	323261.Noc_2235	1.051e-39	150.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,1S8TD@1236|Gammaproteobacteria,1WYQ8@135613|Chromatiales	135613|Chromatiales	U	PFAM small multidrug resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
SRR25158527_k127_2993174_1	1121091.AUMP01000014_gene3429	1.093e-37	153.0	COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli	91061|Bacilli	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	4.1.1.45,4.1.1.52	ko:K03392,ko:K22213	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR25158527_k127_2994204_0	247490.KSU1_D0948	2.466e-57	204.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158527_k127_2994204_1	2340.JV46_13040	3.229e-50	186.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J85H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
SRR25158527_k127_2995343_3	298655.KI912266_gene3875	1.558e-11	76.0	COG2159@1|root,COG2159@2|Bacteria,2IEQP@201174|Actinobacteria,4ETVS@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_2995343_0	330214.NIDE4312	1.979e-138	446.0	COG0330@1|root,COG0330@2|Bacteria,3J0NF@40117|Nitrospirae	40117|Nitrospirae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158527_k127_2995343_2	330214.NIDE4311	8.324e-31	126.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158527_k127_2995343_1	635013.TherJR_0520	7.421e-54	206.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,2610Z@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158527_k127_3006690_0	1304877.KI519400_gene1568	1.182e-67	241.0	COG3618@1|root,COG3618@2|Bacteria,1PB7K@1224|Proteobacteria,2U0DA@28211|Alphaproteobacteria,3JVKV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	MA20_21370	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3006690_1	298654.FraEuI1c_2811	3.179e-33	132.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_3008726_1	1122915.AUGY01000118_gene6526	1.409e-05	51.0	COG0715@1|root,COG0715@2|Bacteria,1UZYY@1239|Firmicutes,4HE24@91061|Bacilli,26RHH@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_3008726_0	766499.C357_09862	9.822e-49	181.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158527_k127_3015811_1	1221522.B723_10885	3.72e-38	146.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158527_k127_3015811_2	1366050.N234_12150	2.371e-09	68.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K11210	-	-	-	-	ko00000,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_3015811_0	1231391.AMZF01000020_gene1927	4.388e-43	162.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	yecD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158527_k127_3018417_0	1144310.PMI07_005447	3.92e-56	209.0	COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3018417_1	298654.FraEuI1c_2797	3.297e-28	123.0	COG0451@1|root,COG0451@2|Bacteria,2GZ4Z@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158527_k127_3021244_1	1117958.PE143B_0112400	2.164e-07	56.0	COG2067@1|root,COG2067@2|Bacteria,1NSMM@1224|Proteobacteria,1SKD1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
SRR25158527_k127_3021244_0	1047013.AQSP01000138_gene1021	4.944e-275	855.0	COG0008@1|root,COG0008@2|Bacteria,2NNRW@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
SRR25158527_k127_3021690_2	926562.Oweho_2711	1.994e-06	54.0	COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,1HYHM@117743|Flavobacteriia	976|Bacteroidetes	E	peptidase	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158527_k127_3021690_0	1283283.ATXA01000006_gene1854	5.043e-72	254.0	COG3435@1|root,COG3435@2|Bacteria,2GZST@201174|Actinobacteria	201174|Actinobacteria	Q	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_3021690_1	1268072.PSAB_03625	3.243e-67	235.0	COG0154@1|root,COG0154@2|Bacteria,1TR9X@1239|Firmicutes,4HAYP@91061|Bacilli,26WNA@186822|Paenibacillaceae	91061|Bacilli	J	amidotransferase, A subunit	gatA3	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158527_k127_3021983_1	1054213.HMPREF9946_00561	1.216e-25	114.0	COG0084@1|root,COG0084@2|Bacteria	2|Bacteria	L	hydrolase, TatD family'	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_19,TatD_DNase
SRR25158527_k127_3021983_0	1499967.BAYZ01000076_gene754	2.244e-163	524.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	aslB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SRR25158527_k127_3026743_0	443144.GM21_1052	4.103e-231	732.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,43SZI@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158527_k127_3026743_3	880072.Desac_2275	1.045e-16	81.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MSC9@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158527_k127_3026743_1	316067.Geob_2120	1.27e-48	179.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
SRR25158527_k127_3026743_2	262316.MAP_1637c	1.075e-18	87.0	COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae	201174|Actinobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_3027730_0	1123072.AUDH01000002_gene2353	7.417e-106	355.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	MA20_07800	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158527_k127_3027730_1	1380356.JNIK01000002_gene4803	3.471e-07	57.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU6Y@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3033065_1	1030157.AFMP01000040_gene1564	5.654e-35	138.0	COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2UK4T@28211|Alphaproteobacteria,2K9ZZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase-like domain	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	-
SRR25158527_k127_3033065_0	247490.KSU1_B0659	3.249e-170	541.0	COG0498@1|root,COG0498@2|Bacteria,2IXKE@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158527_k127_3035265_2	273068.TTE2627	2.84e-27	116.0	2CA4A@1|root,32RQK@2|Bacteria,1VE2U@1239|Firmicutes,24QHD@186801|Clostridia,42GU9@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
SRR25158527_k127_3035265_0	215803.DB30_7969	5.404e-75	260.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158527_k127_3035265_1	706587.Desti_4373	2.157e-73	256.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2MQRK@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRR25158527_k127_3038838_0	443144.GM21_0766	1.953e-214	673.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158527_k127_3038838_2	589865.DaAHT2_1275	4.709e-31	129.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2MK59@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158527_k127_3038838_4	1267535.KB906767_gene3807	1.01e-19	92.0	COG0054@1|root,COG0054@2|Bacteria,3Y3RR@57723|Acidobacteria,2JIYX@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158527_k127_3038838_3	1123511.KB905844_gene1242	1.514e-25	111.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4H3ZR@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
SRR25158527_k127_3038838_1	1123373.ATXI01000010_gene1029	1.838e-36	139.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GHPG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158527_k127_3042162_0	330214.NIDE3564	5e-77	284.0	COG4548@1|root,COG4548@2|Bacteria	2|Bacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA,VWA_2
SRR25158527_k127_3042162_1	285535.JOEY01000056_gene6721	2.031e-18	94.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3044480_0	1122915.AUGY01000020_gene6479	3.019e-22	108.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3044480_1	1049564.TevJSym_aa00360	1.015e-15	78.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1J6E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	involved in response to NO	nnrS	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
SRR25158527_k127_3045722_4	404589.Anae109_0117	1.264e-31	124.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158527_k127_3045722_2	1125863.JAFN01000001_gene2975	2.252e-46	178.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158527_k127_3045722_6	1499967.BAYZ01000147_gene720	0.0001903	52.0	COG2891@1|root,COG2891@2|Bacteria,2NRRJ@2323|unclassified Bacteria	2|Bacteria	M	rod shape-determining protein MreD	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158527_k127_3045722_0	1232437.KL662077_gene1920	9.347e-168	547.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MHV4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
SRR25158527_k127_3045722_1	56780.SYN_00550	1.177e-112	376.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2MQBR@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158527_k127_3045722_3	335543.Sfum_1708	1.301e-40	152.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MS32@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158527_k127_3045722_5	113355.CM001775_gene1716	2.698e-19	89.0	COG0260@1|root,COG0260@2|Bacteria,1G079@1117|Cyanobacteria	1117|Cyanobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158527_k127_304736_0	1324957.K933_13893	2.881e-103	352.0	COG2843@1|root,arCOG07503@2157|Archaea	2157|Archaea	M	enzyme of poly-gamma-glutamate biosynthesis (Capsule formation)	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158527_k127_304736_1	1231391.AMZF01000020_gene1928	8.973e-16	82.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_3050615_1	653045.Strvi_4346	8.93e-05	47.0	COG0346@1|root,COG0346@2|Bacteria,2IIN9@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,Glyoxalase
SRR25158527_k127_3050615_0	1408303.JNJJ01000089_gene3141	1.196e-41	171.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1UEIC@1239|Firmicutes,4HDD8@91061|Bacilli,1ZAQA@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
SRR25158527_k127_3051774_1	1173263.Syn7502_03004	0.0002006	48.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_3051774_2	1033802.SSPSH_000537	0.0005687	47.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,1SDB7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158527_k127_3051774_0	156889.Mmc1_3232	5.285e-47	175.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Thioredoxin	trxA2	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
SRR25158527_k127_3057116_2	1341151.ASZU01000006_gene2951	0.0008796	48.0	2DWMV@1|root,3412A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3057116_1	598467.BrE312_1285	2.098e-17	94.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,1SF34@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,TAT_signal
SRR25158527_k127_3057116_0	443152.MDG893_15357	2.149e-38	147.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,1RZ17@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_3060857_1	748247.AZKH_4257	7.96e-05	53.0	COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,2VQ9W@28216|Betaproteobacteria,2KYMP@206389|Rhodocyclales	206389|Rhodocyclales	C	cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
SRR25158527_k127_3060857_0	118168.MC7420_3515	3.345e-85	296.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3064679_0	269799.Gmet_0956	0.0	1059.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158527_k127_3064679_1	370438.PTH_0226	3.12e-82	283.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,26046@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
SRR25158527_k127_3092025_2	1380355.JNIJ01000018_gene4465	6.876e-20	90.0	2E398@1|root,32Y8V@2|Bacteria,1N7IR@1224|Proteobacteria,2UFHK@28211|Alphaproteobacteria,3K10Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3092025_1	1380355.JNIJ01000018_gene4466	1.322e-58	218.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2UBZM@28211|Alphaproteobacteria,3JYF3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
SRR25158527_k127_3092025_0	1040989.AWZU01000101_gene7412	1.23e-71	244.0	COG2346@1|root,COG2346@2|Bacteria,1MZSM@1224|Proteobacteria,2UCHK@28211|Alphaproteobacteria,3JV8R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial-like globin	MA20_34335	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158527_k127_3099294_2	1121918.ARWE01000001_gene2030	0.000172	49.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42N5U@68525|delta/epsilon subdivisions,2X5GU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158527_k127_3099294_0	604331.AUHY01000001_gene1276	3.213e-30	133.0	COG0614@1|root,COG0614@2|Bacteria,1WIQT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158527_k127_3099294_1	589865.DaAHT2_0849	1.63e-29	128.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,43C3N@68525|delta/epsilon subdivisions,2X7EC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SRR25158527_k127_3105047_0	1123023.JIAI01000001_gene6763	9.578e-43	162.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	dddL	-	1.13.11.6,4.4.1.3	ko:K00452,ko:K11312,ko:K16953	ko00380,ko00920,ko01100,map00380,map00920,map01100	M00038	R02574,R02665	RC00387,RC00747,RC00748	ko00000,ko00001,ko00002,ko01000	-	-	-	AraC_binding,Cupin_2,DMSP_lyase
SRR25158527_k127_3108816_2	1280944.HY17_09590	1.481e-09	62.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2TUHT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158527_k127_3108816_0	1510531.JQJJ01000010_gene1978	7.626e-99	337.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,3JSTE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
SRR25158527_k127_3108816_1	1259795.ARJK01000002_gene414	1.142e-56	207.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,24BBC@186801|Clostridia,42GNP@68295|Thermoanaerobacterales	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	fabG4	-	1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76	ko:K00059,ko:K18009,ko:K19548	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00572,M00787	R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R10917,R11671	RC00029,RC00117,RC00154,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158527_k127_310969_0	113395.AXAI01000020_gene6320	6.976e-35	134.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2TTM8@28211|Alphaproteobacteria,3JW7P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
SRR25158527_k127_310969_1	375286.mma_1189	9.592e-30	124.0	2E3QW@1|root,32YNQ@2|Bacteria,1NFBV@1224|Proteobacteria,2VWPZ@28216|Betaproteobacteria,477JM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Periplasmic lysozyme inhibitor of I-type lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	PliI
SRR25158527_k127_310969_2	1038869.AXAN01000014_gene3348	3.09e-09	66.0	2CN1D@1|root,32SG1@2|Bacteria,1N9DS@1224|Proteobacteria,2W87F@28216|Betaproteobacteria,1K3I0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4410)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4410
SRR25158527_k127_3110673_1	709797.CSIRO_1089	5.234e-06	54.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,3JVGB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
SRR25158527_k127_3110673_0	1121396.KB892935_gene3861	1.809e-51	199.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_311770_0	498761.HM1_1471	7.048e-49	177.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,25F02@186801|Clostridia	186801|Clostridia	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158527_k127_311770_3	43989.cce_1749	5.125e-08	57.0	COG0668@1|root,COG4447@1|root,COG0668@2|Bacteria,COG4447@2|Bacteria,1G0ZM@1117|Cyanobacteria,3KHHU@43988|Cyanothece	1117|Cyanobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
SRR25158527_k127_311770_2	42256.RradSPS_1213	1.173e-17	88.0	COG0668@1|root,COG0668@2|Bacteria,2HRMR@201174|Actinobacteria,4CTPR@84995|Rubrobacteria	84995|Rubrobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
SRR25158527_k127_311770_1	1499967.BAYZ01000030_gene1161	1.282e-40	159.0	COG1131@1|root,COG1131@2|Bacteria,2NR7X@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ccmA	-	3.6.3.41	ko:K01990,ko:K02193	ko02010,map02010	M00254,M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.107	-	-	ABC_tran
SRR25158527_k127_3124648_0	671143.DAMO_3037	8.147e-105	344.0	COG0129@1|root,COG0129@2|Bacteria,2NNSM@2323|unclassified Bacteria	2|Bacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158527_k127_3124648_1	1123072.AUDH01000008_gene290	9.37e-104	348.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TU4F@28211|Alphaproteobacteria,2JV7T@204441|Rhodospirillales	204441|Rhodospirillales	C	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
SRR25158527_k127_3128522_2	401526.TcarDRAFT_1685	3.511e-83	284.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4H2BA@909932|Negativicutes	909932|Negativicutes	I	methylmalonyl-CoA decarboxylase alpha subunit	mmdA	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158527_k127_3128522_0	706587.Desti_4219	2.409e-163	521.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MQ5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
SRR25158527_k127_3128522_3	909663.KI867150_gene1131	1.895e-15	78.0	COG4770@1|root,COG4770@2|Bacteria,1Q2C7@1224|Proteobacteria,437YM@68525|delta/epsilon subdivisions,2X9S9@28221|Deltaproteobacteria,2MSE4@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
SRR25158527_k127_3128522_1	1120972.AUMH01000002_gene2761	9.799e-112	374.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_3128522_4	1200792.AKYF01000009_gene3081	0.0005955	49.0	COG0860@1|root,COG3103@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,26UYQ@186822|Paenibacillaceae	91061|Bacilli	MT	Ami_3	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
SRR25158527_k127_312945_2	443152.MDG893_15075	1.168e-14	82.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_312945_1	935840.JAEQ01000020_gene2336	7.299e-30	121.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158527_k127_312945_0	935261.JAGL01000008_gene2343	1.282e-98	327.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158527_k127_3134095_2	35754.JNYJ01000035_gene3839	1.177e-76	266.0	COG4249@1|root,COG4249@2|Bacteria,2IB3R@201174|Actinobacteria,4DIC8@85008|Micromonosporales	201174|Actinobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_C14
SRR25158527_k127_3134095_1	62928.azo3973	4.481e-101	336.0	COG3179@1|root,COG3409@1|root,COG3179@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	exeA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	-	ko:K02450,ko:K03791,ko:K17733	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko01011,ko02044	9.B.42	GH19	-	AAA_22,Glyco_hydro_19,PG_binding_1
SRR25158527_k127_3134095_0	1123257.AUFV01000002_gene2398	1.166e-175	573.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,1S0VJ@1236|Gammaproteobacteria,1X4WD@135614|Xanthomonadales	135614|Xanthomonadales	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
SRR25158527_k127_3134095_4	945713.IALB_2363	8.334e-28	116.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158527_k127_3134095_3	1122611.KB903944_gene1144	3.758e-44	164.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4EI0E@85012|Streptosporangiales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158527_k127_3145631_2	754035.Mesau_01519	7.005e-10	68.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3145631_0	1509405.GV67_12630	1.094e-25	119.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3145631_1	1297570.MESS4_170003	1.819e-19	101.0	COG3181@1|root,COG3181@2|Bacteria,1PGZ7@1224|Proteobacteria,2V8QA@28211|Alphaproteobacteria,43QSJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3154695_1	868864.Dester_0239	1.284e-17	86.0	COG1550@1|root,COG1550@2|Bacteria,2G47V@200783|Aquificae	200783|Aquificae	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158527_k127_3154695_0	269799.Gmet_1586	2.74e-253	804.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,43UH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158527_k127_3161136_3	4432.XP_010274131.1	7.519e-13	73.0	COG1304@1|root,KOG0538@2759|Eukaryota,37Q8R@33090|Viridiplantae,3GEWX@35493|Streptophyta	35493|Streptophyta	C	peroxisomal (S)-2-hydroxy-acid oxidase	-	GO:0003674,GO:0003824,GO:0003973,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0008150,GO:0008152,GO:0008891,GO:0009853,GO:0009987,GO:0010109,GO:0016032,GO:0016491,GO:0016614,GO:0016899,GO:0019048,GO:0019222,GO:0031323,GO:0035821,GO:0042579,GO:0043094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044003,GO:0044237,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051817,GO:0055114,GO:0065007	1.1.3.15	ko:K11517	ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00630,map01100,map01110,map01120,map01130,map01200,map04146	M00532	R00475	RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SRR25158527_k127_3161136_2	1184267.A11Q_422	1.123e-20	94.0	2BW7N@1|root,32Z97@2|Bacteria,1P2ZF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3161136_0	1192034.CAP_6251	8.635e-92	314.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_3161136_1	1172179.AUKV01000025_gene7985	9.377e-78	274.0	COG1063@1|root,COG1063@2|Bacteria,2GMNX@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_3161136_4	1120972.AUMH01000002_gene2752	0.0003039	45.0	COG3181@1|root,COG3181@2|Bacteria,1TSCN@1239|Firmicutes,4HEPT@91061|Bacilli	91061|Bacilli	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3167886_1	592015.HMPREF1705_01969	8.221e-49	190.0	COG1538@1|root,COG1538@2|Bacteria,3TAY7@508458|Synergistetes	508458|Synergistetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SRR25158527_k127_3167886_2	1121413.JMKT01000009_gene1798	1.422e-05	53.0	COG0457@1|root,COG0457@2|Bacteria,1RFRU@1224|Proteobacteria,42RM9@68525|delta/epsilon subdivisions,2WNVH@28221|Deltaproteobacteria,2M9ZM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158527_k127_3167886_0	1382304.JNIL01000001_gene1506	1.94e-66	236.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,278QK@186823|Alicyclobacillaceae	91061|Bacilli	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_3171833_1	1123502.AQXD01000005_gene1678	8.734e-20	89.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1X3HS@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SRR25158527_k127_3171833_0	667014.Thein_1566	2.625e-218	688.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GH22@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158527_k127_3171833_2	616991.JPOO01000003_gene2381	1.146e-18	91.0	COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1HXT0@117743|Flavobacteriia,23GD9@178469|Arenibacter	976|Bacteroidetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158527_k127_3191896_1	335543.Sfum_1920	1.084e-54	198.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MQEE@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158527_k127_3191896_0	566466.NOR53_3277	3.652e-90	314.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1SKMW@1236|Gammaproteobacteria,1J9PK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158527_k127_3192399_0	1532558.JL39_24305	3.301e-205	656.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,4B7WC@82115|Rhizobiaceae	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158527_k127_3192399_1	262316.MAP_2253	3.986e-22	106.0	COG2079@1|root,COG2079@2|Bacteria,2HVDJ@201174|Actinobacteria,2384S@1762|Mycobacteriaceae	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_3193080_0	1144310.PMI07_005447	2.287e-51	194.0	COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3193080_1	1118054.CAGW01000075_gene3261	1.156e-07	61.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3197182_0	316058.RPB_4414	2.183e-50	189.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3K3D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158527_k127_3197182_1	319003.Bra1253DRAFT_02622	2.159e-48	181.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158527_k127_3201883_1	56107.Cylst_2489	2.875e-88	302.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1HJFJ@1161|Nostocales	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158527_k127_3201883_0	306281.AJLK01000109_gene3129	2.761e-100	332.0	COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,1JKEV@1189|Stigonemataceae	1117|Cyanobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
SRR25158527_k127_320543_1	1205680.CAKO01000026_gene4597	7.366e-20	93.0	COG2128@1|root,COG2128@2|Bacteria,1RC52@1224|Proteobacteria,2U3FR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158527_k127_320543_3	1183438.GKIL_4498	7.086e-07	54.0	COG2128@1|root,COG2128@2|Bacteria,1GDGE@1117|Cyanobacteria	1117|Cyanobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158527_k127_320543_0	1120936.KB907221_gene2112	9.742e-78	271.0	COG2159@1|root,COG2159@2|Bacteria,2GN9D@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SRR25158527_k127_320543_2	1230476.C207_05009	6.877e-12	76.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_320543_4	1232410.KI421412_gene238	3.768e-06	55.0	COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,42UMV@68525|delta/epsilon subdivisions,2WR43@28221|Deltaproteobacteria,43V9Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3217053_1	1380394.JADL01000001_gene3068	1.774e-29	126.0	COG0600@1|root,COG0600@2|Bacteria,1NS93@1224|Proteobacteria	1224|Proteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158527_k127_3217053_0	1144310.PMI07_005439	1.312e-37	157.0	COG0600@1|root,COG0600@2|Bacteria,1PF1W@1224|Proteobacteria,2UQ2K@28211|Alphaproteobacteria,4BJDU@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158527_k127_322480_0	1125863.JAFN01000001_gene2480	1.45e-104	342.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158527_k127_322480_2	880072.Desac_2528	4.691e-46	178.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42QDS@68525|delta/epsilon subdivisions,2WMQ3@28221|Deltaproteobacteria,2MQID@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SRR25158527_k127_322480_1	243231.GSU1907	1.012e-58	211.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,43SK7@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SRR25158527_k127_3226855_2	351627.Csac_2188	0.0008668	42.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia,42ETY@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158527_k127_3226855_0	1121406.JAEX01000003_gene1560	7.125e-49	191.0	COG0477@1|root,COG2814@2|Bacteria,1PG3D@1224|Proteobacteria,42S62@68525|delta/epsilon subdivisions,2WNYR@28221|Deltaproteobacteria,2MGPZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158527_k127_3226855_1	370438.PTH_0496	2.603e-24	109.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,260E4@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
SRR25158527_k127_3228786_7	1484157.PSNIH2_14660	9.241e-46	171.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,3VZBY@53335|Pantoea	1236|Gammaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E0035	DapB_C,DapB_N
SRR25158527_k127_3228786_4	404380.Gbem_4054	1.005e-107	356.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,43SVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_3228786_5	1123376.AUIU01000012_gene1394	2.122e-100	337.0	COG0253@1|root,COG0253@2|Bacteria,3J0JV@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158527_k127_3228786_1	338963.Pcar_2420	1.142e-175	560.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,43U09@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SRR25158527_k127_3228786_8	1499967.BAYZ01000105_gene3496	0.0001576	49.0	COG4733@1|root,COG4733@2|Bacteria,2NQ62@2323|unclassified Bacteria	2|Bacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Cellulase,Dockerin_1,Flg_new,Laminin_G_3,Phage-tail_3
SRR25158527_k127_3228786_2	338963.Pcar_2418	2.649e-171	550.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,43RY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Argininosuccinate lyase C-terminal	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
SRR25158527_k127_3228786_0	330214.NIDE0485	9.332e-193	611.0	COG0137@1|root,COG0137@2|Bacteria,3J0BU@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158527_k127_3228786_6	671143.DAMO_0075	3.477e-100	341.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158527_k127_3228786_3	56780.SYN_02155	1.735e-151	488.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MQ76@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
SRR25158527_k127_3230300_2	575540.Isop_3542	6.876e-72	268.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158527_k127_3230300_1	247490.KSU1_C0185	2.331e-87	297.0	COG1721@1|root,COG1721@2|Bacteria,2IY2F@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158527_k127_3230300_0	215803.DB30_1676	3.533e-130	428.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158527_k127_3230300_3	638303.Thal_1064	0.0005955	49.0	COG0457@1|root,COG1729@1|root,COG3063@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3063@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
SRR25158527_k127_3232510_0	1278073.MYSTI_02092	9.213e-181	597.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
SRR25158527_k127_3234761_0	269799.Gmet_1487	2.631e-110	364.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
SRR25158527_k127_3234761_1	1089553.Tph_c19760	5.963e-48	180.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_3257198_0	671143.DAMO_3017	1.139e-86	297.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158527_k127_3257198_2	398767.Glov_2038	1.978e-28	120.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,43TBU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158527_k127_3257198_3	1382359.JIAL01000001_gene1397	6.369e-15	82.0	2CK1C@1|root,32SJA@2|Bacteria,3Y543@57723|Acidobacteria,2JJTF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3257198_1	338963.Pcar_0650	2.211e-80	280.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,43S2E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YceG-like family	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158527_k127_3257663_5	56780.SYN_00428	0.0002746	48.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_3257663_1	443598.AUFA01000048_gene929	1.838e-38	160.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria,3JR8H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_3257663_3	903818.KI912268_gene2695	2.622e-08	60.0	COG5652@1|root,COG5652@2|Bacteria,3Y82N@57723|Acidobacteria	57723|Acidobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158527_k127_3257663_4	1050201.KB913034_gene1190	6.255e-07	53.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
SRR25158527_k127_3257663_2	909663.KI867150_gene1328	7.356e-28	121.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SRR25158527_k127_3257663_0	1519464.HY22_07360	5.83e-55	210.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158527_k127_3259109_0	138119.DSY5022	1.418e-87	294.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,260MZ@186807|Peptococcaceae	186801|Clostridia	E	PFAM ABC transporter	livF1	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158527_k127_3259109_1	383372.Rcas_1895	6.026e-83	284.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi,374Z9@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158527_k127_3266477_4	876269.ARWA01000001_gene2144	3.667e-09	59.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,3N9KG@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
SRR25158527_k127_3266477_3	1307761.L21SP2_1117	1.839e-29	125.0	COG0526@1|root,COG0526@2|Bacteria,2J8ET@203691|Spirochaetes	203691|Spirochaetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158527_k127_3266477_1	671143.DAMO_0003	5.561e-70	248.0	COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158527_k127_3266477_2	497965.Cyan7822_5589	3.146e-69	239.0	COG0302@1|root,COG0302@2|Bacteria,1G1K8@1117|Cyanobacteria,3KFYR@43988|Cyanothece	1117|Cyanobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.folE,iJN678.folE	GTP_cyclohydroI
SRR25158527_k127_3266477_0	338963.Pcar_0200	1.366e-107	368.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158527_k127_3268994_0	404589.Anae109_4242	1.941e-89	304.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
SRR25158527_k127_3268994_1	338963.Pcar_0643	6.816e-49	179.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,43SIE@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158527_k127_3268994_2	378806.STAUR_3769	4.528e-41	158.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2YVUS@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158527_k127_3270634_1	706587.Desti_0194	6.109e-65	228.0	COG4275@1|root,COG4275@2|Bacteria,1PKNN@1224|Proteobacteria,42XSF@68525|delta/epsilon subdivisions,2WTCB@28221|Deltaproteobacteria,2MSBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158527_k127_3270634_0	381666.H16_B1483	1.314e-124	412.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,1K55C@119060|Burkholderiaceae	28216|Betaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158527_k127_3270634_2	1379698.RBG1_1C00001G0621	2.609e-30	124.0	COG4275@1|root,COG4275@2|Bacteria	2|Bacteria	S	Chromate resistance exported protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist,HTH_18,Rhodanese
SRR25158527_k127_3271174_0	448385.sce5924	7.064e-90	302.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,43AB6@68525|delta/epsilon subdivisions,2X259@28221|Deltaproteobacteria,2YZEP@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158527_k127_3271174_1	42256.RradSPS_1677	2.331e-60	216.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CRW6@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158527_k127_3279055_3	330214.NIDE3483	1.988e-45	167.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2,YCII
SRR25158527_k127_3279055_1	331869.BAL199_16858	1.435e-65	227.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SRR25158527_k127_3279055_2	1267535.KB906767_gene4247	1.112e-48	176.0	COG3795@1|root,COG3795@2|Bacteria,3Y5F1@57723|Acidobacteria,2JN7W@204432|Acidobacteriia	204432|Acidobacteriia	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158527_k127_3279055_0	240015.ACP_1948	1.567e-219	685.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158527_k127_3279055_4	2002.JOEQ01000031_gene1648	9.977e-43	158.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
SRR25158527_k127_3282870_3	1205680.CAKO01000002_gene2257	6.49e-11	67.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,2JSPE@204441|Rhodospirillales	204441|Rhodospirillales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158527_k127_3282870_2	1379270.AUXF01000004_gene3289	6.309e-18	88.0	COG2010@1|root,COG2010@2|Bacteria,1ZUYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158527_k127_3282870_0	667632.KB890165_gene2393	2.607e-66	234.0	COG0625@1|root,COG0625@2|Bacteria,1RA4M@1224|Proteobacteria,2VS6D@28216|Betaproteobacteria,1K0Y5@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
SRR25158527_k127_3282870_1	1388763.O165_009290	9.071e-57	216.0	COG4191@1|root,COG4191@2|Bacteria,1R8JK@1224|Proteobacteria,1SC56@1236|Gammaproteobacteria,1YW7K@136845|Pseudomonas putida group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158527_k127_3290422_0	859657.RPSI07_1716	0.0	1121.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,2VH6A@28216|Betaproteobacteria,1K0R2@119060|Burkholderiaceae	28216|Betaproteobacteria	K	SMART Resolvase, RNase H domain protein fold	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
SRR25158527_k127_3292316_3	472759.Nhal_0811	1.004e-37	145.0	COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,1SGQS@1236|Gammaproteobacteria,1X1KT@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
SRR25158527_k127_3292316_2	331869.BAL199_19628	8.807e-50	186.0	COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,2VEQZ@28211|Alphaproteobacteria,4BQPH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
SRR25158527_k127_3292316_1	1234664.AMRO01000019_gene754	1.761e-51	199.0	COG0584@1|root,COG3540@1|root,COG0584@2|Bacteria,COG3540@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli,1WHRB@129337|Geobacillus	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.3.1,3.1.4.46	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	M00126	R01030,R01470,R04620	RC00017,RC00425	ko00000,ko00001,ko00002,ko01000	-	-	-	GDPD
SRR25158527_k127_3292316_0	1331060.RLDS_22000	5.977e-54	197.0	COG1024@1|root,COG1024@2|Bacteria,1MY8F@1224|Proteobacteria,2U9B9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158527_k127_3298759_2	316067.Geob_2359	1.211e-42	160.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,43T0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SRR25158527_k127_3298759_0	880072.Desac_0022	3.072e-116	389.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2MR8N@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158527_k127_3298759_1	338966.Ppro_1346	4.252e-71	252.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2WRNN@28221|Deltaproteobacteria,43TA8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
SRR25158527_k127_3298759_3	586413.CCDL010000002_gene2279	5.541e-14	75.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,23J5X@182709|Oceanobacillus	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158527_k127_3299517_1	289376.THEYE_A1151	7.615e-65	225.0	COG0064@1|root,COG0064@2|Bacteria,3J0FK@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158527_k127_3299517_0	671143.DAMO_0810	1.994e-200	635.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158527_k127_3299517_2	671143.DAMO_0811	2.539e-20	93.0	COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158527_k127_3299517_3	1087448.Eab7_1745	1.743e-15	79.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3WDXU@539002|Bacillales incertae sedis	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158527_k127_3302861_0	395495.Lcho_0048	1.119e-30	128.0	COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VMIP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
SRR25158527_k127_3302861_1	1142394.PSMK_26760	1.089e-26	115.0	COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
SRR25158527_k127_3303438_1	330214.NIDE3490	2.947e-46	171.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
SRR25158527_k127_3303438_0	269799.Gmet_3493	7.076e-217	677.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome c oxidase, subunit I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SRR25158527_k127_3304937_0	443144.GM21_0708	4.855e-114	372.0	COG3618@1|root,COG3618@2|Bacteria,1PF81@1224|Proteobacteria,42Z8K@68525|delta/epsilon subdivisions,2WU9E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3304937_1	748658.KB907312_gene1719	0.0006269	47.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SRR25158527_k127_331231_1	1123060.JONP01000001_gene1641	1.191e-59	216.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,2JUQX@204441|Rhodospirillales	204441|Rhodospirillales	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158527_k127_331231_0	1173028.ANKO01000224_gene1260	3.899e-71	250.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3313155_1	469371.Tbis_2522	1.368e-08	58.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4EEF0@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_3313155_0	1033806.HTIA_2528	1.664e-21	107.0	arCOG10209@1|root,arCOG10209@2157|Archaea,2XTUW@28890|Euryarchaeota,241EH@183963|Halobacteria	183963|Halobacteria	S	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_3
SRR25158527_k127_3313509_0	443152.MDG893_15015	1.217e-74	261.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,1RNY1@1236|Gammaproteobacteria,46A35@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	KR domain	-	-	1.1.1.304,1.1.1.76	ko:K03366	ko00650,map00650	-	R02855,R02946,R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158527_k127_3313509_1	1123060.JONP01000011_gene2982	2.299e-12	78.0	COG0715@1|root,COG0715@2|Bacteria,1RCUI@1224|Proteobacteria,2VFIN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3323916_0	1206730.BAGA01000177_gene4610	1e-35	138.0	COG2239@1|root,COG2239@2|Bacteria,2I9TV@201174|Actinobacteria,4G8U3@85025|Nocardiaceae	201174|Actinobacteria	P	Divalent cation transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE
SRR25158527_k127_332706_2	1172185.KB911518_gene2685	3.107e-14	74.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4FVXQ@85025|Nocardiaceae	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158527_k127_332706_1	1089545.KB913037_gene1407	1.469e-15	88.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria,4E9TU@85010|Pseudonocardiales	201174|Actinobacteria	P	NMT1-like family	ssuA_3	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_332706_0	1231391.AMZF01000068_gene2179	3.991e-29	123.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_3327426_0	264732.Moth_1809	1.608e-198	632.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
SRR25158527_k127_3330587_1	1094558.ME5_00733	2.093e-43	168.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158527_k127_3330587_0	671143.DAMO_3119	3.379e-53	196.0	COG1893@1|root,COG1893@2|Bacteria,2NPMG@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158527_k127_3334755_0	1121405.dsmv_2310	1.923e-63	232.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42U0W@68525|delta/epsilon subdivisions,2WQRX@28221|Deltaproteobacteria,2MPQV@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_3334755_1	1120970.AUBZ01000018_gene3332	5.537e-10	70.0	COG5492@1|root,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1RZEW@1236|Gammaproteobacteria,46A4V@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566
SRR25158527_k127_3334845_6	382464.ABSI01000010_gene3665	9.467e-35	141.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158527_k127_3334845_2	1201288.M900_0274	6.094e-48	178.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,42RCU@68525|delta/epsilon subdivisions,2MT7P@213481|Bdellovibrionales,2WMXY@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
SRR25158527_k127_3334845_4	1340493.JNIF01000003_gene3955	1.959e-43	166.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
SRR25158527_k127_3334845_1	331869.BAL199_20065	7.424e-65	231.0	COG1712@1|root,COG1712@2|Bacteria,1MX8S@1224|Proteobacteria,2TV48@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
SRR25158527_k127_3334845_0	1030157.AFMP01000040_gene1551	4.128e-113	383.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSZ8@28211|Alphaproteobacteria,2K8YM@204457|Sphingomonadales	204457|Sphingomonadales	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_3334845_3	1460635.JCM19038_2389	4.102e-44	176.0	COG2271@1|root,COG2271@2|Bacteria,1V0VC@1239|Firmicutes,4HCQG@91061|Bacilli	91061|Bacilli	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158527_k127_3334845_7	1307759.JOMJ01000003_gene1778	2.156e-29	128.0	COG1102@1|root,COG1102@2|Bacteria,1R82J@1224|Proteobacteria,42M5Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
SRR25158527_k127_3334845_5	926560.KE387023_gene1591	4.232e-41	158.0	COG0590@1|root,COG0590@2|Bacteria,1WMK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	FJ	PFAM Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
SRR25158527_k127_3334845_9	671143.DAMO_2368	2.513e-15	84.0	COG3678@1|root,COG3678@2|Bacteria,2NRWA@2323|unclassified Bacteria	2|Bacteria	NPTU	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
SRR25158527_k127_3334845_8	589924.Ferp_1092	6.45e-22	106.0	COG2220@1|root,arCOG00497@2157|Archaea,2XZBG@28890|Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158527_k127_3335686_1	479434.Sthe_3489	2.383e-18	88.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi	2|Bacteria	J	PFAM Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase,FCD
SRR25158527_k127_3335686_2	123899.JPQP01000004_gene678	5.805e-16	81.0	COG1917@1|root,COG1917@2|Bacteria,1RJBF@1224|Proteobacteria,2W48U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3335686_0	675635.Psed_3034	1.637e-98	339.0	COG5016@1|root,COG5016@2|Bacteria,2IA4P@201174|Actinobacteria	201174|Actinobacteria	C	Conserved carboxylase domain	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
SRR25158527_k127_3346210_0	243231.GSU0367	5.234e-93	315.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WIPW@28221|Deltaproteobacteria,43TZ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SMART Elongator protein 3 MiaB NifB	yhcC-1	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
SRR25158527_k127_3346210_1	1532558.JL39_00805	1.2e-40	162.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,4B76P@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	MA20_20705	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158527_k127_334753_1	1122604.JONR01000009_gene2461	2.493e-21	99.0	COG0071@1|root,COG0071@2|Bacteria,1N0RH@1224|Proteobacteria,1SBJN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158527_k127_334753_0	1336243.JAEA01000006_gene314	1.108e-63	228.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2U0IK@28211|Alphaproteobacteria,1JSZW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Lon protease (S16) C-terminal proteolytic domain	MA20_45155	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158527_k127_3349889_0	671143.DAMO_3080	5.985e-210	665.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158527_k127_3349889_1	522772.Dacet_2360	3.447e-18	90.0	COG0589@1|root,COG0589@2|Bacteria,2GFI3@200930|Deferribacteres	200930|Deferribacteres	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_3350167_0	478741.JAFS01000002_gene551	0.0	1187.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46SVA@74201|Verrucomicrobia,37FY0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158527_k127_3351976_2	376733.IT41_12665	9.256e-10	63.0	COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2TW6Y@28211|Alphaproteobacteria,2PYNN@265|Paracoccus	28211|Alphaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,NHL,Redoxin,Thioredoxin_8
SRR25158527_k127_3351976_1	1349767.GJA_5357	6.036e-33	130.0	COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2VRG2@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158527_k127_3351976_0	1000565.METUNv1_02912	4.815e-133	431.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,2KV6B@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
SRR25158527_k127_3367308_1	1454004.AW11_03982	7.48e-06	52.0	2DZRB@1|root,32VGU@2|Bacteria,1NK4X@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3367308_0	1192034.CAP_6251	4.9e-76	267.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_336880_0	1382356.JQMP01000001_gene814	1.001e-56	211.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_336880_1	331869.BAL199_05144	1.949e-53	197.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,4BPJE@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	MA20_23640	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_337057_1	1162668.LFE_0642	6.96e-81	273.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	40117|Nitrospirae	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158527_k127_337057_0	289376.THEYE_A0627	7.456e-84	287.0	COG0294@1|root,COG0294@2|Bacteria,3J0NS@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158527_k127_3373205_0	1232410.KI421421_gene3630	4.627e-108	363.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,42MBD@68525|delta/epsilon subdivisions,2WJT1@28221|Deltaproteobacteria,43SAH@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Peptidase family M28	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158527_k127_3378120_2	257310.BB4414	4.08e-11	63.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2VIAN@28216|Betaproteobacteria,3T283@506|Alcaligenaceae	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_3378120_0	404380.Gbem_1452	1.027e-116	389.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_3378120_1	1121085.AUCI01000007_gene1386	1.58e-48	181.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,1ZASR@1386|Bacillus	91061|Bacilli	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	yvrA	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,CbiZ
SRR25158527_k127_3379582_5	457396.CSBG_00046	6.685e-39	148.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,36DP8@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158527_k127_3379582_4	644282.Deba_2939	2.162e-48	174.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2WP4K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158527_k127_3379582_0	243231.GSU2860	0.0	1080.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158527_k127_3379582_3	404589.Anae109_1908	5.72e-61	216.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2YUYC@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SRR25158527_k127_3379582_2	880072.Desac_1461	2.803e-64	221.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2MQJX@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SRR25158527_k127_3379582_1	1232410.KI421428_gene1224	4.532e-156	497.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43S5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	RNA polymerase I subunit A N-terminus	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SRR25158527_k127_3385070_0	1297617.JPJD01000050_gene1926	2.345e-83	294.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,2697G@186813|unclassified Clostridiales	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
SRR25158527_k127_3388167_1	1121456.ATVA01000005_gene2980	4.451e-08	64.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,42UZS@68525|delta/epsilon subdivisions,2X77T@28221|Deltaproteobacteria,2MA9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051,ko:K15551	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	NMT1,NMT1_2
SRR25158527_k127_3388167_0	1219031.BBJR01000062_gene2058	4.414e-42	156.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,4AB4T@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_1	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158527_k127_3389283_2	671143.DAMO_1165	6.829e-48	175.0	COG0843@1|root,COG0843@2|Bacteria,2NNTQ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158527_k127_3389283_1	671143.DAMO_1164	1.998e-57	205.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
SRR25158527_k127_3389283_3	243231.GSU1650	5.601e-13	75.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
SRR25158527_k127_3389283_0	880073.Calab_3613	6.244e-94	319.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944	-	ko:K00412,ko:K02635,ko:K02637,ko:K03887,ko:K03891,ko:K15879	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
SRR25158527_k127_339460_0	404589.Anae109_3139	1.092e-201	636.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
SRR25158527_k127_3396069_0	443152.MDG893_15040	3.994e-100	338.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria	1224|Proteobacteria	E	ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_3396069_1	1174684.EBMC1_17152	3.421e-05	55.0	COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2UK4T@28211|Alphaproteobacteria,2K9ZZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase-like domain	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	-
SRR25158527_k127_3398716_0	381666.H16_B2148	1.704e-185	594.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VJKJ@28216|Betaproteobacteria,1K04G@119060|Burkholderiaceae	28216|Betaproteobacteria	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158527_k127_3400047_1	370438.PTH_1367	1.514e-97	326.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,260EM@186807|Peptococcaceae	186801|Clostridia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158527_k127_3400047_0	796606.BMMGA3_06055	2.965e-161	517.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus	91061|Bacilli	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
SRR25158527_k127_3404869_2	196490.AUEZ01000105_gene2948	2.405e-33	142.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_3404869_0	1125973.JNLC01000010_gene1772	9.342e-76	267.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2VG8G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
SRR25158527_k127_3404869_1	1160137.KB907308_gene6991	8.609e-61	220.0	COG2084@1|root,COG2084@2|Bacteria,2GTGE@201174|Actinobacteria,4G4IQ@85025|Nocardiaceae	201174|Actinobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,F420_oxidored,NAD_binding_2
SRR25158527_k127_3405310_0	1002809.SSIL_2517	1.047e-17	88.0	COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HABU@91061|Bacilli,26EIN@186818|Planococcaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	BPD_transp_1
SRR25158527_k127_3407316_0	1121440.AUMA01000007_gene1048	1.138e-58	216.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2M927@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_3412109_1	397948.Cmaq_1163	0.0002511	49.0	COG2423@1|root,arCOG01035@2157|Archaea	2157|Archaea	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	ala	-	1.4.1.1	ko:K19244	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_3412109_0	1231391.AMZF01000003_gene3114	1.333e-33	142.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_3415653_0	1242864.D187_001768	4.914e-261	814.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158527_k127_3415653_1	690850.Desaf_0510	8.592e-154	497.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2M8JZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158527_k127_3415653_5	1504822.CCNO01000015_gene965	4.111e-23	101.0	COG0228@1|root,COG0228@2|Bacteria	2|Bacteria	J	mitochondrial translation	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158527_k127_3415653_6	555779.Dthio_PD1343	1.417e-20	97.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MCGN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158527_k127_3415653_4	335543.Sfum_2999	1.823e-24	112.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,42TGI@68525|delta/epsilon subdivisions,2WQJU@28221|Deltaproteobacteria,2MQMB@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158527_k127_3415653_2	717231.Flexsi_1962	6.279e-134	439.0	COG0336@1|root,COG4752@1|root,COG0336@2|Bacteria,COG4752@2|Bacteria,2GEM4@200930|Deferribacteres	200930|Deferribacteres	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
SRR25158527_k127_3415653_3	500635.MITSMUL_05229	6.428e-26	108.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4H4PC@909932|Negativicutes	909932|Negativicutes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158527_k127_3417507_0	1120936.KB907209_gene1257	4.65e-23	106.0	COG2358@1|root,COG2358@2|Bacteria	2|Bacteria	G	TRAP transporter, solute receptor (TAXI family	-	-	3.2.1.52	ko:K01207,ko:K07080	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2491,NMT1_3,Pkinase,TIR_2,TPR_10
SRR25158527_k127_3417507_1	1306174.JODP01000004_gene1237	4.386e-07	61.0	COG0715@1|root,COG0715@2|Bacteria,2H3BK@201174|Actinobacteria	201174|Actinobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,NMT1_2
SRR25158527_k127_3418024_1	56780.SYN_01761	1.15e-06	55.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02246,ko:K08084	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.15.2	-	-	GspH,N_methyl
SRR25158527_k127_3418024_2	1249627.D779_3848	0.0001508	50.0	COG4967@1|root,COG4967@2|Bacteria,1RKWI@1224|Proteobacteria,1SEEI@1236|Gammaproteobacteria,1X27N@135613|Chromatiales	135613|Chromatiales	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
SRR25158527_k127_3418024_0	56780.SYN_01757	3.677e-12	75.0	COG4966@1|root,COG4966@2|Bacteria,1Q8WE@1224|Proteobacteria,439J3@68525|delta/epsilon subdivisions,2X4VK@28221|Deltaproteobacteria,2MSHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
SRR25158527_k127_3419811_0	1476876.JOJO01000036_gene4375	8.568e-191	617.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_3419811_1	1123229.AUBC01000013_gene2551	4.295e-15	84.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctA
SRR25158527_k127_3427847_3	946483.Cenrod_2073	2.274e-20	101.0	COG0438@1|root,COG0457@1|root,COG2242@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG2242@2|Bacteria,1N5N9@1224|Proteobacteria,2VVSK@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
SRR25158527_k127_3427847_0	1210908.HSB1_22820	1.53e-44	174.0	COG2423@1|root,arCOG01035@2157|Archaea,2XT4P@28890|Euryarchaeota,23TF8@183963|Halobacteria	183963|Halobacteria	E	ornithine cyclodeaminase mu-crystallin	ocd2	-	1.4.1.1	ko:K19244	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_3427847_1	797209.ZOD2009_16563	2.129e-38	148.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria	183963|Halobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158527_k127_3427847_2	1131269.AQVV01000020_gene2207	1.056e-24	106.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase_like
SRR25158527_k127_3429879_2	1219035.NT2_01_01700	0.0002535	46.0	COG2271@1|root,COG2271@2|Bacteria,1QW8H@1224|Proteobacteria,2TWSW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_3429879_0	443152.MDG893_15065	1.178e-64	233.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,1RQG7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	phtD	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_3429879_1	335543.Sfum_0404	3.627e-24	111.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM toluene tolerance family protein	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR25158527_k127_3440503_0	525904.Tter_1871	3.257e-78	272.0	COG4867@1|root,COG4867@2|Bacteria,2NQZ8@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
SRR25158527_k127_3440503_1	46234.ANA_C10267	6.109e-38	151.0	COG4398@1|root,COG4398@2|Bacteria,1G0TB@1117|Cyanobacteria,1HM6Z@1161|Nostocales	1117|Cyanobacteria	S	FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158527_k127_3441369_1	1405.DJ92_5286	3.889e-54	205.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_3441369_2	414684.RC1_1514	2.505e-53	198.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_3441369_0	1173027.Mic7113_2967	1.348e-72	260.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	2|Bacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3441369_4	1231391.AMZF01000006_gene2822	1.737e-12	74.0	COG0662@1|root,COG0662@2|Bacteria,1NUXF@1224|Proteobacteria,2W29X@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_3441369_3	43989.cce_4098	4.831e-29	130.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,3KGJS@43988|Cyanothece	1117|Cyanobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3445867_1	266117.Rxyl_2315	1.569e-29	120.0	2BZ0R@1|root,2Z7U0@2|Bacteria,2GU1J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Nitrile hydratase alpha	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
SRR25158527_k127_3445867_2	266117.Rxyl_2314	1.899e-25	108.0	2DBV6@1|root,32TY6@2|Bacteria	2|Bacteria	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
SRR25158527_k127_3445867_3	1121861.KB899922_gene3093	7.195e-16	81.0	2DSG6@1|root,33G0T@2|Bacteria,1QTRS@1224|Proteobacteria,2TVX1@28211|Alphaproteobacteria,2JY7F@204441|Rhodospirillales	204441|Rhodospirillales	S	Nitrile hydratase beta subunit	-	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
SRR25158527_k127_3445867_0	671143.DAMO_2938	8.38e-173	550.0	COG1274@1|root,COG1274@2|Bacteria,2NQRD@2323|unclassified Bacteria	2|Bacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	pckG	-	4.1.1.32,4.1.1.49	ko:K01596,ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003,M00170	R00341,R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP,PEPCK_C,PEPCK_N
SRR25158527_k127_3446995_2	857087.Metme_2130	1.615e-21	107.0	COG1652@1|root,COG4995@1|root,COG1652@2|Bacteria,COG4995@2|Bacteria,1MZXQ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158527_k127_3446995_0	330214.NIDE4175	4.142e-59	219.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158527_k127_3446995_1	247634.GPB2148_856	5.425e-47	173.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1J6NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hit1	-	-	-	-	-	-	-	-	-	-	-	HIT
SRR25158527_k127_345231_3	1144310.PMI07_005585	5.858e-25	114.0	COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_345231_4	1122132.AQYH01000007_gene2060	1.266e-21	100.0	COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1N78G@1224|Proteobacteria,2UHM9@28211|Alphaproteobacteria,4BDEK@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META,MliC
SRR25158527_k127_345231_1	85643.Tmz1t_3131	8.612e-101	334.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2VHGT@28216|Betaproteobacteria,2KZYM@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158527_k127_345231_2	76114.ebA5307	2.063e-86	294.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2VKUM@28216|Betaproteobacteria,2KY9I@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158527_k127_345231_0	76114.ebA5306	4.691e-106	357.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VK9Y@28216|Betaproteobacteria,2KV1M@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158527_k127_345231_5	76114.ebA5304	3.204e-20	91.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,2KXZ1@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158527_k127_3453056_0	402777.KB235903_gene1316	1.162e-62	224.0	29SNW@1|root,30DUI@2|Bacteria,1G3JZ@1117|Cyanobacteria,1HEXD@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM AZL_007920 MXAN_0976 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3453056_1	1121378.KB899704_gene2402	6.016e-27	118.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	dsbE	-	-	ko:K02199,ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
SRR25158527_k127_3453056_2	670307.HYPDE_32783	1.027e-06	55.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2TRQQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
SRR25158527_k127_3456291_0	1194972.MVAC_00110	2.576e-90	312.0	COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria,237YQ@1762|Mycobacteriaceae	201174|Actinobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_3456291_2	234267.Acid_2478	1.521e-12	71.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
SRR25158527_k127_3456291_1	926550.CLDAP_01370	5.095e-82	277.0	COG0026@1|root,COG0026@2|Bacteria,2G5PV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
SRR25158527_k127_3460762_0	479434.Sthe_3181	4.944e-88	308.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_3461667_4	504728.K649_10820	1.312e-17	86.0	COG0517@1|root,COG0517@2|Bacteria,1WMQJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158527_k127_3461667_3	1250278.JQNQ01000001_gene345	9.188e-32	129.0	COG1764@1|root,COG1764@2|Bacteria,4PK2I@976|Bacteroidetes,1I3KT@117743|Flavobacteriia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158527_k127_3461667_0	509191.AEDB02000003_gene999	1.58e-75	261.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,25CI8@186801|Clostridia,3WJ6E@541000|Ruminococcaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158527_k127_3461667_1	56780.SYN_01583	7.759e-59	207.0	2AVTU@1|root,31MME@2|Bacteria,1NQ7V@1224|Proteobacteria,42XCN@68525|delta/epsilon subdivisions,2WTFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3461667_2	748280.NH8B_0019	1.743e-57	203.0	COG0730@1|root,COG0730@2|Bacteria,1PYEK@1224|Proteobacteria,2W2DY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158527_k127_3465673_0	1123399.AQVE01000007_gene1186	1.299e-80	279.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,45ZSX@72273|Thiotrichales	72273|Thiotrichales	NU	Type II IV secretion system protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
SRR25158527_k127_3465673_1	1278073.MYSTI_04470	6.388e-40	152.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_3465673_2	479436.Vpar_1250	1.355e-06	54.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,4H249@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
SRR25158527_k127_3465855_1	1231391.AMZF01000046_gene961	5.793e-20	97.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_3465855_0	202954.BBNK01000005_gene1745	1.025e-63	228.0	COG1024@1|root,COG1024@2|Bacteria,1MVB1@1224|Proteobacteria,1RQQX@1236|Gammaproteobacteria,3NKIM@468|Moraxellaceae	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	hcaA	-	4.1.2.41,4.2.1.101	ko:K18383	ko00360,ko01100,ko01110,map00360,map01100,map01110	-	R05772,R05773	RC00307,RC01468,RC01828	ko00000,ko00001,ko01000	-	-	iJN746.PP_3358	ECH_1
SRR25158527_k127_346900_0	1306174.JODP01000004_gene913	2.03e-14	85.0	COG2141@1|root,COG2141@2|Bacteria,2IEM9@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158527_k127_3469094_4	1121405.dsmv_2625	4.182e-08	64.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,42UZS@68525|delta/epsilon subdivisions,2X77T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051,ko:K15551	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	NMT1,NMT1_2
SRR25158527_k127_3469094_2	1122621.ATZA01000030_gene2694	6.401e-45	169.0	COG0116@1|root,COG0116@2|Bacteria,4NPBD@976|Bacteroidetes,1IXA8@117747|Sphingobacteriia	976|Bacteroidetes	L	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_3469094_0	1121396.KB893058_gene2565	2.024e-63	228.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Peptidase_S9
SRR25158527_k127_3469094_1	246197.MXAN_1966	4.037e-53	191.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158527_k127_3469094_3	298654.FraEuI1c_2854	1.3e-09	67.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria,4EUJC@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3483328_1	1121106.JQKB01000022_gene3728	0.0005303	44.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2U65K@28211|Alphaproteobacteria,2JZ8K@204441|Rhodospirillales	204441|Rhodospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_3483328_0	1121396.KB892935_gene3861	2.885e-48	189.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_3484359_0	479434.Sthe_2892	5.523e-156	514.0	COG0145@1|root,COG0145@2|Bacteria,2G7YY@200795|Chloroflexi,27ZD4@189775|Thermomicrobia	2|Bacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
SRR25158527_k127_3487868_1	399795.CtesDRAFT_PD2788	2.592e-41	160.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2VT72@28216|Betaproteobacteria,4AED9@80864|Comamonadaceae	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158527_k127_3487868_2	460265.Mnod_6160	6.366e-39	150.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,1JV04@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SRR25158527_k127_3487868_0	203124.Tery_2349	1.561e-64	233.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
SRR25158527_k127_3489008_0	1131269.AQVV01000004_gene588	1.009e-66	239.0	COG1619@1|root,COG1619@2|Bacteria	2|Bacteria	V	carboxypeptidase activity	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158527_k127_3489008_1	1499967.BAYZ01000139_gene140	1.506e-34	140.0	COG1680@1|root,COG1680@2|Bacteria,2NPA1@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158527_k127_34921_0	717774.Marme_3499	4.26e-32	138.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,1RQN1@1236|Gammaproteobacteria,1XHGV@135619|Oceanospirillales	135619|Oceanospirillales	S	C4-dicarboxylate ABC transporter substrate-binding protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158527_k127_3498790_0	479434.Sthe_1092	6.292e-217	692.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SRR25158527_k127_3501678_4	243231.GSU3447	2.057e-15	77.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,43URV@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158527_k127_3501678_3	338963.Pcar_2330	1.029e-40	152.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158527_k127_3501678_0	62928.azo0103	1.368e-117	388.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria,2KW58@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158527_k127_3501678_1	525904.Tter_2232	6.697e-76	267.0	COG1319@1|root,COG1319@2|Bacteria,2NQP8@2323|unclassified Bacteria	2|Bacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158527_k127_3501678_2	518766.Rmar_2766	5.24e-42	163.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_3504299_1	1192034.CAP_4624	2.564e-83	284.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PVS@68525|delta/epsilon subdivisions,2WJ7B@28221|Deltaproteobacteria,2YXQQ@29|Myxococcales	28221|Deltaproteobacteria	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
SRR25158527_k127_3504299_0	266117.Rxyl_0283	1.883e-84	286.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158527_k127_3505678_1	179408.Osc7112_5179	4.591e-88	296.0	COG1020@1|root,COG1020@2|Bacteria,1G4I1@1117|Cyanobacteria,1HAAY@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM AMP-dependent synthetase ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
SRR25158527_k127_3505678_4	706587.Desti_3849	4.871e-28	116.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,2MSHG@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158527_k127_3505678_2	316067.Geob_3359	6.811e-33	132.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,43V44@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158527_k127_3505678_0	215803.DB30_7404	2.281e-154	512.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158527_k127_3505678_3	589865.DaAHT2_1241	8.051e-30	118.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2MI3B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158527_k127_3511892_0	330214.NIDE2085	1.731e-118	409.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
SRR25158527_k127_3529575_2	519989.ECTPHS_09148	9.761e-11	68.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales	135613|Chromatiales	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
SRR25158527_k127_3529575_3	1267535.KB906767_gene303	7.917e-08	65.0	COG2982@1|root,COG2982@2|Bacteria,3Y3Z4@57723|Acidobacteria,2JIBU@204432|Acidobacteriia	204432|Acidobacteriia	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
SRR25158527_k127_3529575_1	358681.BBR47_06140	5.783e-105	349.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,26URK@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158527_k127_3529575_0	526227.Mesil_2494	4.376e-127	426.0	COG4177@1|root,COG4177@2|Bacteria,1WI2C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	branched-chain amino acid transport system, permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158527_k127_3530372_3	43759.JNWK01000016_gene272	1.708e-41	158.0	COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Metallophos
SRR25158527_k127_3530372_5	40571.JOEA01000006_gene4412	2.759e-06	55.0	COG1409@1|root,COG1409@2|Bacteria,2GIT1@201174|Actinobacteria,4E0S4@85010|Pseudonocardiales	201174|Actinobacteria	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158527_k127_3530372_0	36331.EPrPI00000017145	1.451e-84	293.0	COG1304@1|root,KOG0538@2759|Eukaryota,1MD1U@121069|Pythiales	121069|Pythiales	C	Peroxisomal (S)-2-hydroxy-acid oxidase. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
SRR25158527_k127_3530372_4	1340434.AXVA01000013_gene356	1.009e-07	63.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,4HHFE@91061|Bacilli,1ZHPX@1386|Bacillus	91061|Bacilli	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3530372_2	1120949.KB903314_gene303	4.979e-47	184.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_3530372_1	1120949.KB903314_gene302	9.216e-68	242.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1,SBP_bac_6
SRR25158527_k127_3531249_1	675635.Psed_3691	2.101e-37	154.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_3531249_0	3847.GLYMA08G00740.3	5.4e-65	232.0	COG1062@1|root,KOG0022@2759|Eukaryota,37MA7@33090|Viridiplantae,3G8YI@35493|Streptophyta,4JH4B@91835|fabids	35493|Streptophyta	Q	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_3534800_1	479434.Sthe_0262	4.169e-70	250.0	COG0402@1|root,COG0402@2|Bacteria,2G8TD@200795|Chloroflexi,27ZAA@189775|Thermomicrobia	189775|Thermomicrobia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158527_k127_3534800_0	269799.Gmet_1295	4.58e-139	454.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,43S56@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SRR25158527_k127_3535952_1	1125863.JAFN01000001_gene557	9.551e-56	205.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158527_k127_3535952_0	717785.HYPMC_0241	3.656e-85	288.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U1QF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158527_k127_3539956_2	1267533.KB906734_gene3719	1.154e-104	349.0	COG0837@1|root,COG0837@2|Bacteria,3Y3P1@57723|Acidobacteria,2JIE1@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
SRR25158527_k127_3539956_0	525904.Tter_0413	8.021e-189	602.0	COG0364@1|root,COG0364@2|Bacteria,2NNUR@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158527_k127_3539956_1	1267535.KB906767_gene54	5.194e-142	459.0	COG0176@1|root,COG0176@2|Bacteria,3Y6V9@57723|Acidobacteria	57723|Acidobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158527_k127_3539956_3	247490.KSU1_B0456	3.189e-54	198.0	COG0698@1|root,COG0698@2|Bacteria,2IZSB@203682|Planctomycetes	203682|Planctomycetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
SRR25158527_k127_3539956_4	693986.MOC_2729	5.986e-21	93.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,1JR13@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Belongs to the transketolase family	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158527_k127_3542401_0	316067.Geob_3271	1.006e-223	703.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,43TR2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158527_k127_3542401_2	443144.GM21_2305	3.474e-180	589.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158527_k127_3542401_1	671143.DAMO_1503	2.201e-182	577.0	COG0436@1|root,COG0436@2|Bacteria,2NQG2@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	yfdZ	GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iEcSMS35_1347.EcSMS35_2531,iSBO_1134.SBO_2405	Aminotran_1_2
SRR25158527_k127_3547278_1	909663.KI867150_gene494	1.799e-55	197.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,43BW3@68525|delta/epsilon subdivisions,2X5Y1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158527_k127_3547278_0	338966.Ppro_2189	1.92e-135	442.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,43TQ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM aminotransferase, class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158527_k127_3547278_2	215803.DB30_5962	9.374e-13	68.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2YYUB@29|Myxococcales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158527_k127_354829_0	886293.Sinac_6796	7.231e-93	326.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
SRR25158527_k127_3551979_0	1232410.KI421424_gene1719	3.684e-77	269.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,43SED@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Elongator protein 3, MiaB family, Radical SAM	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SRR25158527_k127_3551979_1	1123072.AUDH01000002_gene2353	1.13e-22	104.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	MA20_07800	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158527_k127_3555532_0	1532558.JL39_00915	3.274e-28	127.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3555532_1	195250.CM001776_gene1633	2.03e-14	85.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3557617_0	443152.MDG893_15045	1.347e-82	287.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria	1224|Proteobacteria	E	ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_3557617_1	690585.JNNU01000009_gene534	3.305e-21	103.0	COG1840@1|root,COG1840@2|Bacteria,1PGNJ@1224|Proteobacteria,2V7JA@28211|Alphaproteobacteria,4BDDZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158527_k127_3561733_0	269796.Rru_A2098	1.71e-32	146.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2JQWJ@204441|Rhodospirillales	204441|Rhodospirillales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SRR25158527_k127_3561733_1	1238182.C882_2881	9.06e-05	49.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,2JPMC@204441|Rhodospirillales	204441|Rhodospirillales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158527_k127_3570845_0	102125.Xen7305DRAFT_00036110	6.646e-157	508.0	COG1899@1|root,COG1899@2|Bacteria,1GHV9@1117|Cyanobacteria,3VN9Q@52604|Pleurocapsales	1117|Cyanobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
SRR25158527_k127_3571684_0	1340434.AXVA01000012_gene2953	7.2e-91	310.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,4HBJ1@91061|Bacilli	91061|Bacilli	C	Conserved carboxylase domain	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
SRR25158527_k127_3571684_1	1297742.A176_06772	2.228e-62	221.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,434AF@68525|delta/epsilon subdivisions,2X23S@28221|Deltaproteobacteria,2YVSR@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158527_k127_3575857_1	644966.Tmar_2131	4.466e-85	289.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,3WDT7@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158527_k127_3575857_0	1382306.JNIM01000001_gene330	1.551e-86	293.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158527_k127_3575857_5	44689.DDB0187319	1.879e-13	75.0	298SS@1|root,2RFTZ@2759|Eukaryota,3XF6X@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3575857_4	246969.TAM4_812	3.783e-14	82.0	COG1082@1|root,arCOG01895@2157|Archaea,2XUTU@28890|Euryarchaeota,2436S@183968|Thermococci	183968|Thermococci	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158527_k127_3575857_2	593117.TGAM_1016	2.74e-61	229.0	COG1840@1|root,arCOG00227@2157|Archaea,2Y6PD@28890|Euryarchaeota,24507@183968|Thermococci	183968|Thermococci	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158527_k127_3575857_3	246969.TAM4_778	1.633e-48	184.0	COG1178@1|root,arCOG00163@2157|Archaea,2XUE2@28890|Euryarchaeota,2450Y@183968|Thermococci	183968|Thermococci	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158527_k127_3592395_5	273068.TTE2273	5.821e-35	137.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158527_k127_3592395_1	1121918.ARWE01000001_gene2256	6.099e-65	226.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,43SEU@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S5, C-terminal domain	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158527_k127_3592395_3	1254432.SCE1572_45645	5.568e-39	149.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2WQ8U@28221|Deltaproteobacteria,2YVEW@29|Myxococcales	28221|Deltaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158527_k127_3592395_2	443144.GM21_3313	2.524e-55	199.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,43SZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SRR25158527_k127_3592395_4	706587.Desti_5276	8.119e-37	143.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MQJ8@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SRR25158527_k127_3592395_7	316067.Geob_3612	1.078e-21	95.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,43VH4@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SRR25158527_k127_3592395_0	632292.Calhy_1015	9.428e-79	267.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42F2S@68295|Thermoanaerobacterales	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SRR25158527_k127_3592395_6	429009.Adeg_1513	2.337e-33	131.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,42GS5@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SRR25158527_k127_3595280_0	204669.Acid345_3770	0.0	1050.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria,2JIVQ@204432|Acidobacteriia	204432|Acidobacteriia	L	dead deah	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SRR25158527_k127_3595280_1	330214.NIDE2578	4.404e-54	198.0	2F9RH@1|root,3421I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3609629_1	269799.Gmet_0890	3.3e-46	172.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158527_k127_3609629_0	502025.Hoch_4636	5.13e-278	874.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158527_k127_3620191_3	1121335.Clst_0503	3.59e-06	57.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WGZP@541000|Ruminococcaceae	186801|Clostridia	E	Xaa-Pro aminopeptidase	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_3620191_2	1131269.AQVV01000022_gene2217	7.628e-09	65.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	fosB	GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896	2.5.1.18	ko:K11210,ko:K21253,ko:K21264,ko:K21265	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Glyoxalase
SRR25158527_k127_3620191_0	1121928.AUHE01000016_gene265	1.316e-23	115.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria,4GAC0@85026|Gordoniaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_3620191_1	28152.DJ57_2047	1.288e-20	94.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,41FDY@629|Yersinia	1236|Gammaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iEcSMS35_1347.EcSMS35_0678,iSbBS512_1146.SbBS512_E0590	CN_hydrolase
SRR25158527_k127_3621291_0	671143.DAMO_2996	2.295e-287	894.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SRR25158527_k127_3625662_3	246194.CHY_2393	3.638e-20	92.0	COG1978@1|root,COG1978@2|Bacteria,1TPAB@1239|Firmicutes,2487X@186801|Clostridia,42HVI@68295|Thermoanaerobacterales	186801|Clostridia	C	Glycine reductase complex component B subunit gamma	grdB	-	1.21.4.2	ko:K10672	-	-	-	-	ko00000,ko01000	-	-	-	GRDB
SRR25158527_k127_3625662_1	457415.HMPREF1006_00827	1.914e-90	309.0	COG1978@1|root,COG1978@2|Bacteria,3TA3Z@508458|Synergistetes	508458|Synergistetes	S	Selenoprotein B, glycine betaine sarcosine D-proline reductase family	-	-	1.21.4.2	ko:K10672	-	-	-	-	ko00000,ko01000	-	-	-	GRDB
SRR25158527_k127_3625662_4	1122915.AUGY01000020_gene6479	7.054e-09	69.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3625662_0	1007105.PT7_0956	1.285e-126	412.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2W0AM@28216|Betaproteobacteria,3T617@506|Alcaligenaceae	28216|Betaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_3625662_2	225849.swp_1323	3.506e-28	120.0	2BW1G@1|root,32QYR@2|Bacteria,1N2EP@1224|Proteobacteria,1SAHB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
SRR25158527_k127_36425_1	1121403.AUCV01000022_gene3529	1.379e-24	112.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria,2MKZK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158527_k127_36425_0	1120949.KB903314_gene306	2.587e-83	286.0	COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158527_k127_3644334_0	1304888.ATWF01000001_gene1920	4.334e-117	381.0	COG0059@1|root,COG0059@2|Bacteria,2GEM8@200930|Deferribacteres	200930|Deferribacteres	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158527_k127_3644334_1	472759.Nhal_0107	1.039e-24	108.0	2C8BN@1|root,32RKS@2|Bacteria,1N56Z@1224|Proteobacteria,1SDJD@1236|Gammaproteobacteria,1X1EU@135613|Chromatiales	135613|Chromatiales	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
SRR25158527_k127_3645667_0	85643.Tmz1t_4068	4.41e-64	237.0	2CC4B@1|root,3267W@2|Bacteria,1RJP5@1224|Proteobacteria,2VU2U@28216|Betaproteobacteria,2KZ3X@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3645667_1	525897.Dbac_1842	6.901e-45	174.0	COG1840@1|root,COG1840@2|Bacteria,1N9WT@1224|Proteobacteria	1224|Proteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158527_k127_3648224_0	446462.Amir_4013	1.807e-37	153.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria,4E0H8@85010|Pseudonocardiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158527_k127_3648224_1	1463936.JOJI01000029_gene3267	1.635e-21	102.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_3654473_1	237368.SCABRO_01197	4.251e-43	158.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
SRR25158527_k127_3654473_2	118161.KB235922_gene3843	2.727e-27	116.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158527_k127_3654473_0	1347368.HG964408_gene7115	4.101e-57	203.0	COG3340@1|root,COG3340@2|Bacteria,1TRBA@1239|Firmicutes,4HB19@91061|Bacilli,1ZC4Z@1386|Bacillus	91061|Bacilli	E	Belongs to the peptidase S51 family	ygaJ	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158527_k127_3661844_0	1047013.AQSP01000073_gene1101	9.122e-110	361.0	COG0281@1|root,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	mez_1	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
SRR25158527_k127_3661844_2	670487.Ocepr_2130	6.694e-49	179.0	COG5502@1|root,COG5502@2|Bacteria,1WJW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
SRR25158527_k127_3661844_1	192952.MM_2504	3.187e-73	254.0	COG0484@1|root,arCOG02846@2157|Archaea,2XV5D@28890|Euryarchaeota,2N95Q@224756|Methanomicrobia	224756|Methanomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158527_k127_3674433_1	679926.Mpet_1693	1.28e-14	84.0	COG0235@1|root,arCOG04226@2157|Archaea,2XYQT@28890|Euryarchaeota,2N9R0@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158527_k127_3674433_0	1172188.KB911821_gene1528	5.939e-97	336.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FE5K@85021|Intrasporangiaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_3675611_0	640081.Dsui_0784	4.488e-165	521.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2VMMF@28216|Betaproteobacteria,2KV9B@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SRR25158527_k127_3675611_1	522306.CAP2UW1_3689	1.623e-39	153.0	2C0PI@1|root,32VVI@2|Bacteria,1N1H7@1224|Proteobacteria,2VUDK@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3675611_2	333138.LQ50_20190	1.77e-27	121.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	araD	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,UPF0066
SRR25158527_k127_3675611_3	333138.LQ50_20190	6.851e-24	110.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	araD	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,UPF0066
SRR25158527_k127_3675611_4	1303518.CCALI_01929	2.233e-06	57.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	CP_1111	GO:0005575,GO:0005576	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2,TENA_THI-4
SRR25158527_k127_3680037_0	1197706.AKKK01000022_gene2191	9.581e-121	401.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,1W8D3@1268|Micrococcaceae	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_3680353_2	1095769.CAHF01000014_gene3067	3.031e-08	56.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,474JZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
SRR25158527_k127_3680353_0	1382306.JNIM01000001_gene3467	6.252e-103	349.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158527_k127_3680353_1	1123023.JIAI01000018_gene2484	1.32e-64	231.0	COG0726@1|root,COG0726@2|Bacteria,2GM0X@201174|Actinobacteria,4EC9Z@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SRR25158527_k127_3682286_2	398767.Glov_2547	1.652e-08	56.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158527_k127_3682286_0	1232410.KI421428_gene1082	9.835e-85	293.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,43THQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulatory protein IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158527_k127_3682286_1	262724.TT_C0752	8.225e-73	250.0	COG0247@1|root,COG0247@2|Bacteria,1WIPC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158527_k127_3683874_2	1121123.AUAO01000003_gene2405	0.0007318	42.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,2KFQ2@204458|Caulobacterales	204458|Caulobacterales	F	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158527_k127_3683874_0	935840.JAEQ01000019_gene2104	2.861e-65	235.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria,43PT0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	xdhB	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158527_k127_3683874_1	1123288.SOV_1c06600	1.324e-56	201.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,4H5AR@909932|Negativicutes	909932|Negativicutes	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
SRR25158527_k127_3686183_1	1123023.JIAI01000001_gene6772	4.786e-34	135.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4DZ54@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158527_k127_3686183_0	443152.MDG893_15085	4.212e-57	213.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3686183_2	443152.MDG893_15085	2.238e-17	87.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3687919_0	1123371.ATXH01000017_gene638	2.06e-248	781.0	COG0466@1|root,COG0466@2|Bacteria,2GICM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Found in ATP-dependent protease La (LON)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158527_k127_3687919_1	1125863.JAFN01000001_gene1069	6.843e-43	162.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-2	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158527_k127_3687919_2	398767.Glov_0183	7.118e-18	87.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,43V33@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
SRR25158527_k127_3691021_0	671143.DAMO_2217	3.051e-44	167.0	COG2854@1|root,COG2854@2|Bacteria	2|Bacteria	Q	intermembrane phospholipid transfer	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
SRR25158527_k127_3691021_1	468059.AUHA01000002_gene600	0.0002171	48.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1IQFC@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	yiaD	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
SRR25158527_k127_3700176_2	861299.J421_1880	4.175e-45	170.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
SRR25158527_k127_3700176_0	861299.J421_1872	2.756e-260	810.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158527_k127_3700176_1	118173.KB235914_gene2350	9.37e-138	448.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1H8TZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_370198_2	589924.Ferp_0095	0.0003855	43.0	COG1001@1|root,arCOG00693@2157|Archaea,2XV8C@28890|Euryarchaeota,246QY@183980|Archaeoglobi	183980|Archaeoglobi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
SRR25158527_k127_370198_1	690850.Desaf_1578	1.78e-18	90.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SRR25158527_k127_370198_0	909663.KI867150_gene31	1.731e-87	301.0	COG0043@1|root,COG0043@2|Bacteria,1Q5FS@1224|Proteobacteria	1224|Proteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_3706516_0	1278073.MYSTI_04123	1.261e-209	664.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158527_k127_3706516_2	1232410.KI421418_gene2307	1.974e-61	223.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,43VZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158527_k127_3706516_1	760568.Desku_1847	6.369e-87	295.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,2603K@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SRR25158527_k127_3707522_7	1267534.KB906757_gene797	4.569e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,3Y5X6@57723|Acidobacteria,2JK4W@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158527_k127_3707522_5	1429046.RR21198_5412	6.179e-50	180.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4G1DS@85025|Nocardiaceae	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158527_k127_3707522_4	562970.Btus_0180	4.062e-55	196.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,279QJ@186823|Alicyclobacillaceae	91061|Bacilli	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SRR25158527_k127_3707522_2	880072.Desac_1429	3.469e-92	306.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MRHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SRR25158527_k127_3707522_1	398767.Glov_1373	1.197e-128	419.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,43TN3@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SRR25158527_k127_3707522_6	338963.Pcar_0729	2.25e-41	156.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,43V08@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158527_k127_3707522_0	765913.ThidrDRAFT_2798	3.639e-146	468.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,1RNAD@1236|Gammaproteobacteria,1WWQI@135613|Chromatiales	135613|Chromatiales	H	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SRR25158527_k127_3707522_3	765913.ThidrDRAFT_2799	1.976e-65	228.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,1RME4@1236|Gammaproteobacteria,1WWRV@135613|Chromatiales	135613|Chromatiales	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
SRR25158527_k127_3707546_0	251229.Chro_1508	2.769e-60	212.0	COG0454@1|root,COG0454@2|Bacteria,1GQF0@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158527_k127_3707546_1	1089553.Tph_c05410	3.411e-24	110.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,42EWT@68295|Thermoanaerobacterales	186801|Clostridia	T	Signal transduction histidine kinase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
SRR25158527_k127_3714797_1	1122223.KB890699_gene657	1.261e-19	89.0	2AQI0@1|root,31FQP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3714797_0	1120949.KB903314_gene306	1.061e-115	385.0	COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158527_k127_3714797_2	234267.Acid_7541	1.404e-07	63.0	COG0322@1|root,COG0322@2|Bacteria	2|Bacteria	L	excinuclease ABC activity	yurQ	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342,ko:K03703,ko:K04096	ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG
SRR25158527_k127_3718909_1	41431.PCC8801_3684	2.868e-135	451.0	COG1020@1|root,COG3882@1|root,COG1020@2|Bacteria,COG3882@2|Bacteria,1GM4C@1117|Cyanobacteria,3KJ7V@43988|Cyanothece	1117|Cyanobacteria	Q	Pfam:HxxPF_rpt	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
SRR25158527_k127_3718909_0	1124780.ANNU01000008_gene2662	1.039e-200	655.0	COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia	976|Bacteroidetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158527_k127_3718909_2	714943.Mucpa_5289	3.406e-81	276.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,1IP20@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158527_k127_3718909_3	1519464.HY22_13075	5.846e-78	266.0	COG2755@1|root,COG2755@2|Bacteria,1FET3@1090|Chlorobi	1090|Chlorobi	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
SRR25158527_k127_372843_0	1231391.AMZF01000110_gene916	1.616e-191	609.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,3T2PP@506|Alcaligenaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_3731283_4	643562.Daes_3113	1.278e-09	66.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,2MB5V@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158527_k127_3731283_3	443143.GM18_4418	9.67e-28	119.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,43VB9@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SRR25158527_k127_3731283_0	1232410.KI421422_gene2047	3.353e-243	759.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,43TH9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATP synthase alpha/beta chain, C terminal domain	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158527_k127_3731283_2	706587.Desti_3706	2.014e-81	280.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2MQDF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158527_k127_3731283_1	1125863.JAFN01000001_gene2671	4.618e-174	550.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158527_k127_3738946_2	1499967.BAYZ01000196_gene3073	8.837e-52	188.0	COG2379@1|root,COG2379@2|Bacteria,2NNQP@2323|unclassified Bacteria	2|Bacteria	G	MOFRL family	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
SRR25158527_k127_3738946_1	404589.Anae109_0319	1.399e-75	266.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42QF3@68525|delta/epsilon subdivisions,2WKPQ@28221|Deltaproteobacteria,2YYXT@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158527_k127_3738946_0	1121396.KB893107_gene1848	8.261e-76	260.0	COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
SRR25158527_k127_3741810_0	479434.Sthe_2399	2.603e-56	205.0	COG0614@1|root,COG0614@2|Bacteria,2G6EF@200795|Chloroflexi,27XQF@189775|Thermomicrobia	189775|Thermomicrobia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158527_k127_3741810_3	1242864.D187_000950	9.334e-06	55.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42QJX@68525|delta/epsilon subdivisions,2WKPN@28221|Deltaproteobacteria,2Z26U@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_3741810_2	398720.MED217_10372	1.96e-20	105.0	COG3202@1|root,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia,2XJSD@283735|Leeuwenhoekiella	976|Bacteroidetes	P	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
SRR25158527_k127_3741810_1	1122128.AUEE01000016_gene2072	2.603e-42	163.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli,4GY72@90964|Staphylococcaceae	91061|Bacilli	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158527_k127_3741835_0	1123060.JONP01000012_gene2758	1.69e-64	230.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,2JS33@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3741835_1	1349820.M707_15940	6.482e-27	123.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158527_k127_3741835_2	671143.DAMO_2097	4.722e-07	51.0	COG2853@1|root,COG2853@2|Bacteria,2NRQC@2323|unclassified Bacteria	2|Bacteria	M	MlaA lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
SRR25158527_k127_3745422_0	1499967.BAYZ01000036_gene2418	0.0	1015.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158527_k127_3745422_1	1037409.BJ6T_31870	3.439e-07	52.0	2E46N@1|root,32Z2M@2|Bacteria,1N6SH@1224|Proteobacteria,2UHDJ@28211|Alphaproteobacteria,3K55U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3750529_2	221288.JH992901_gene5641	2.022e-13	72.0	COG1225@1|root,COG1278@1|root,COG1225@2|Bacteria,COG1278@2|Bacteria,1GB7U@1117|Cyanobacteria,1JK51@1189|Stigonemataceae	1117|Cyanobacteria	KO	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	AhpC-TSA,CSD
SRR25158527_k127_3750529_3	218284.CCDN010000002_gene1979	1.914e-07	53.0	COG1225@1|root,COG1225@2|Bacteria,1V24A@1239|Firmicutes,4HFUX@91061|Bacilli,1ZEQT@1386|Bacillus	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158527_k127_3750529_1	1173263.Syn7502_03004	2.928e-42	168.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_3750529_0	156889.Mmc1_0275	4.034e-52	194.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2TTQS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_27940	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158527_k127_3758198_2	1532558.JL39_06905	4.832e-18	96.0	COG1840@1|root,COG1840@2|Bacteria,1PGNI@1224|Proteobacteria,2V7J9@28211|Alphaproteobacteria,4B9P8@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11
SRR25158527_k127_3758198_0	1536775.H70737_09015	8.353e-48	182.0	COG0451@1|root,COG0451@2|Bacteria,1TWPP@1239|Firmicutes,4HCTV@91061|Bacilli,26RTK@186822|Paenibacillaceae	91061|Bacilli	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158527_k127_3758198_1	1110502.TMO_0012	1.755e-39	160.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_376832_0	269799.Gmet_0366	1.467e-212	673.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,43U97@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158527_k127_376832_1	243231.GSU3112	1.686e-159	522.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,43UK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158527_k127_3770102_2	414684.RC1_1921	4.154e-29	118.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2JSC3@204441|Rhodospirillales	204441|Rhodospirillales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158527_k127_3770102_1	666684.AfiDRAFT_1063	1.656e-41	166.0	COG2128@1|root,COG2128@2|Bacteria,1N56H@1224|Proteobacteria,2UABU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158527_k127_3770102_0	882378.RBRH_02656	2.719e-67	239.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VJE6@28216|Betaproteobacteria,1JZP1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158527_k127_3773136_3	1547437.LL06_00635	2.65e-20	93.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,43JX9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
SRR25158527_k127_3773136_4	908340.HMPREF9406_2195	4.329e-09	68.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3773136_0	1121937.AUHJ01000010_gene1698	4.009e-126	413.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,465DU@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iSbBS512_1146.SbBS512_E1908	DAHP_synth_1
SRR25158527_k127_3773136_1	46429.BV95_01102	1.576e-42	167.0	28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria,2U95E@28211|Alphaproteobacteria,2KCHY@204457|Sphingomonadales	204457|Sphingomonadales	S	S1/P1 Nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
SRR25158527_k127_3773136_2	1121035.AUCH01000022_gene3203	4.379e-36	139.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria,2KWZK@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3774368_0	867903.ThesuDRAFT_00352	3.954e-159	514.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
SRR25158527_k127_3774368_1	1502852.FG94_00985	4.36e-15	79.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2W8YT@28216|Betaproteobacteria,476D8@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,Response_reg
SRR25158527_k127_3777696_1	94624.Bpet3549	8.475e-05	53.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,3T1MD@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_3777696_0	1463855.JOHV01000036_gene5806	6.944e-14	83.0	COG0715@1|root,COG0715@2|Bacteria,2IGX1@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3783613_1	391625.PPSIR1_02546	4.99e-07	52.0	28HI5@1|root,2Z7TP@2|Bacteria,1Q2A9@1224|Proteobacteria,437X1@68525|delta/epsilon subdivisions,2X36R@28221|Deltaproteobacteria,2YUJV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3783613_0	272134.KB731324_gene4530	2.595e-198	628.0	COG0017@1|root,COG0017@2|Bacteria,1G015@1117|Cyanobacteria,1H7PZ@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158527_k127_3784346_4	324057.Pjdr2_1720	0.0008255	49.0	COG0715@1|root,COG0715@2|Bacteria,1V9ZY@1239|Firmicutes,4HTB1@91061|Bacilli,26W8N@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_3784346_1	43989.cce_4098	1.199e-72	258.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,3KGJS@43988|Cyanothece	1117|Cyanobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_3784346_3	1122915.AUGY01000118_gene6536	7.471e-19	98.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_3784346_0	1487953.JMKF01000045_gene2705	5.018e-132	430.0	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria,1H7D3@1150|Oscillatoriales	1117|Cyanobacteria	P	K -dependent Na Ca exchanger	ecm27	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158527_k127_3784346_2	983917.RGE_05160	2.997e-23	102.0	COG2979@1|root,COG2979@2|Bacteria,1R221@1224|Proteobacteria,2WI84@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF533)	-	-	-	-	-	-	-	-	-	-	-	-	DUF533
SRR25158527_k127_3785459_0	1122604.JONR01000010_gene3925	1.028e-23	107.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1X55Z@135614|Xanthomonadales	135614|Xanthomonadales	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SRR25158527_k127_3785459_1	1173028.ANKO01000135_gene2513	1.176e-14	79.0	COG0277@1|root,COG0277@2|Bacteria,1G176@1117|Cyanobacteria,1H7RA@1150|Oscillatoriales	1117|Cyanobacteria	C	FAD linked oxidases, C-terminal domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158527_k127_3785893_0	868864.Dester_0409	2.825e-88	295.0	COG0177@1|root,COG0177@2|Bacteria,2G3TX@200783|Aquificae	200783|Aquificae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158527_k127_3785893_2	331869.BAL199_05944	1.842e-34	139.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,4BQP3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	NUDIX domain	MA20_44635	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158527_k127_3785893_1	443143.GM18_0717	1.077e-52	203.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SRR25158527_k127_3789287_0	720554.Clocl_0405	9.838e-101	343.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WG7J@541000|Ruminococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158527_k127_3789287_1	1120973.AQXL01000105_gene2554	1.477e-35	140.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,278JG@186823|Alicyclobacillaceae	91061|Bacilli	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158527_k127_379009_1	1487923.DP73_13975	8.406e-42	160.0	COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,249RZ@186801|Clostridia,2610Z@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_379009_0	671143.DAMO_1073	0.0	1157.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158527_k127_3796184_0	767817.Desgi_1198	1.804e-125	416.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,2612F@186807|Peptococcaceae	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
SRR25158527_k127_3796184_1	880072.Desac_2837	3.359e-109	367.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2WJ06@28221|Deltaproteobacteria,2MQ54@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158527_k127_3796184_2	1107311.Q767_01960	5.386e-08	58.0	COG0346@1|root,COG0346@2|Bacteria,4NQ7X@976|Bacteroidetes,1I33U@117743|Flavobacteriia,2NW5T@237|Flavobacterium	976|Bacteroidetes	E	Glyoxalase bleomycin resistance protein dioxygenase	gloA	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158527_k127_3801499_3	1122915.AUGY01000118_gene6536	7.233e-11	73.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_3801499_2	525897.Dbac_1842	3.468e-47	185.0	COG1840@1|root,COG1840@2|Bacteria,1N9WT@1224|Proteobacteria	1224|Proteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158527_k127_3801499_1	710686.Mycsm_03169	4.179e-59	218.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_3801499_0	1192034.CAP_6251	3.341e-94	321.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_3809826_0	234267.Acid_0587	0.0	1195.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
SRR25158527_k127_3813309_1	710685.MycrhN_4733	5.665e-64	233.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_3813309_0	1217718.ALOU01000026_gene3554	4.525e-113	367.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2VK8F@28216|Betaproteobacteria,1JZYT@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
SRR25158527_k127_3816010_0	1121439.dsat_2288	1.735e-79	271.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158527_k127_3816010_1	290397.Adeh_2583	1.613e-32	131.0	COG1959@1|root,COG1959@2|Bacteria,1Q19C@1224|Proteobacteria,4375I@68525|delta/epsilon subdivisions,2WRDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158527_k127_3816010_2	483219.LILAB_03340	6.94e-32	138.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SRR25158527_k127_3816010_5	388467.A19Y_2947	6.455e-25	115.0	COG0028@1|root,COG4032@1|root,COG0028@2|Bacteria,COG4032@2|Bacteria,1G36U@1117|Cyanobacteria,1HFJ5@1150|Oscillatoriales	1117|Cyanobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158527_k127_3816010_4	1382306.JNIM01000001_gene3715	1.804e-28	121.0	COG4032@1|root,COG4032@2|Bacteria,2G8KU@200795|Chloroflexi	200795|Chloroflexi	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158527_k127_3816010_3	986075.CathTA2_3037	1.275e-30	125.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SRR25158527_k127_3817163_1	1232410.KI421425_gene1526	2.941e-68	234.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158527_k127_3817163_0	316067.Geob_3595	2.841e-104	348.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,43TJM@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158527_k127_3817163_2	204669.Acid345_1581	9.832e-14	73.0	COG0316@1|root,COG0316@2|Bacteria,3Y4ZB@57723|Acidobacteria,2JJEX@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
SRR25158527_k127_3829217_1	1144319.PMI16_03288	3.726e-30	127.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158527_k127_3829217_2	1071085.KK033114_gene736	3.155e-23	106.0	arCOG08934@1|root,arCOG08934@2157|Archaea,2XXBA@28890|Euryarchaeota	28890|Euryarchaeota	Q	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158527_k127_3829217_0	1231391.AMZF01000121_gene3464	2.842e-101	338.0	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VNRV@28216|Betaproteobacteria	28216|Betaproteobacteria	I	esterase	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,COesterase
SRR25158527_k127_3829270_0	1168059.KB899087_gene2145	2.843e-113	376.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria,3EZS5@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_3829270_1	266265.Bxe_B0451	1.169e-50	187.0	COG0695@1|root,COG0695@2|Bacteria,1RC6T@1224|Proteobacteria,2VQW9@28216|Betaproteobacteria,1K5H4@119060|Burkholderiaceae	28216|Betaproteobacteria	O	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Glutaredoxin
SRR25158527_k127_3832088_0	237368.SCABRO_03313	1.339e-140	460.0	COG0469@1|root,COG0469@2|Bacteria,2IY60@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SRR25158527_k127_3832088_1	1306990.BARG01000030_gene3384	1.525e-79	277.0	COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria	201174|Actinobacteria	Q	Pfam Cupin	-	-	1.13.11.38,1.13.11.4	ko:K00450,ko:K11948	ko00350,ko00624,ko01100,ko01120,map00350,map00624,map01100,map01120	-	R02656,R07657	RC00764,RC00937	ko00000,ko00001,ko01000	-	-	-	Cupin_2
SRR25158527_k127_3832088_2	1484157.PSNIH2_18465	3.149e-20	97.0	COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,1RP1V@1236|Gammaproteobacteria,3VXW3@53335|Pantoea	1236|Gammaproteobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
SRR25158527_k127_3832749_0	1227499.C493_00160	6.069e-57	206.0	COG1116@1|root,arCOG00193@2157|Archaea,2XXDP@28890|Euryarchaeota,23VWW@183963|Halobacteria	183963|Halobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158527_k127_3832749_1	1463820.JOGW01000008_gene1433	1.542e-08	66.0	COG0715@1|root,COG0715@2|Bacteria,2I9KK@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_3834215_0	671143.DAMO_1019	2.106e-187	595.0	COG1488@1|root,COG1488@2|Bacteria,2NNUE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
SRR25158527_k127_3834947_0	395964.KE386496_gene361	1.577e-97	338.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,3NCIH@45404|Beijerinckiaceae	28211|Alphaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_3845032_4	1122915.AUGY01000020_gene6479	3.401e-07	60.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_3845032_1	1122604.JONR01000006_gene2513	3.325e-36	142.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158527_k127_3845032_0	1532558.JL39_00915	3.644e-53	200.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3845032_2	1380394.JADL01000005_gene5673	2.445e-25	114.0	COG0725@1|root,COG0725@2|Bacteria,1RCHM@1224|Proteobacteria,2VGBX@28211|Alphaproteobacteria,2JWBR@204441|Rhodospirillales	204441|Rhodospirillales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
SRR25158527_k127_3845032_3	443152.MDG893_15275	4.009e-21	98.0	COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,1RZ8H@1236|Gammaproteobacteria,46CXF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3845775_1	395964.KE386496_gene2671	1.009e-07	63.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,3NB7B@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	NMT1-like family	nrt	-	-	ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16.1,3.A.1.16.2	-	-	NMT1_2
SRR25158527_k127_3845775_0	1144310.PMI07_006458	1.726e-27	125.0	COG1840@1|root,COG1840@2|Bacteria,1N9WT@1224|Proteobacteria,2UV2M@28211|Alphaproteobacteria,4BM48@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
SRR25158527_k127_3852325_1	867903.ThesuDRAFT_01357	1.19e-20	91.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia	186801|Clostridia	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158527_k127_3852325_0	1449126.JQKL01000016_gene2867	1.085e-174	574.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,26828@186813|unclassified Clostridiales	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_3856916_1	671143.DAMO_1913	1.548e-17	86.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158527_k127_3856916_0	330214.NIDE0690	1.716e-100	346.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
SRR25158527_k127_3861079_2	56780.SYN_00631	1.136e-18	85.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MQUM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158527_k127_3861079_0	156889.Mmc1_3630	3.671e-160	515.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158527_k127_3861079_1	671143.DAMO_1616	7.581e-127	420.0	COG1034@1|root,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SRR25158527_k127_3864812_1	1207063.P24_07061	4.921e-88	305.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,2UCG6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
SRR25158527_k127_3864812_2	416870.llmg_0911	3.014e-06	53.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HNQH@91061|Bacilli,1YCFG@1357|Lactococcus	91061|Bacilli	K	Nitrogen regulatory protein P-II	glnB	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158527_k127_3864812_0	1449044.JMLE01000029_gene106	3.295e-167	529.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,1WAY5@1268|Micrococcaceae	201174|Actinobacteria	C	Transketolase, C-terminal domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158527_k127_3870597_0	1198452.Jab_1c16510	1.963e-40	160.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,2VM30@28216|Betaproteobacteria,475TU@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158527_k127_3870597_1	436229.JOEH01000028_gene2101	2.95e-10	69.0	COG0715@1|root,COG0715@2|Bacteria,2HFUV@201174|Actinobacteria,2NMNB@228398|Streptacidiphilus	201174|Actinobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_3875668_3	357808.RoseRS_0912	1.397e-30	133.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,377HX@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_3875668_0	309801.trd_1809	9.214e-38	155.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_3875668_2	479434.Sthe_2505	3.336e-34	143.0	COG0589@1|root,COG0589@2|Bacteria,2GBUS@200795|Chloroflexi,27Z69@189775|Thermomicrobia	189775|Thermomicrobia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_3875668_1	289376.THEYE_A0363	7.644e-37	144.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158527_k127_3876060_1	765911.Thivi_0813	2.09e-64	226.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXYB@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158527_k127_3876060_0	472759.Nhal_2257	1.37e-111	371.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WWSW@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158527_k127_3876060_2	318167.Sfri_1814	9.988e-32	127.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,2QAVB@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
SRR25158527_k127_3885661_0	488538.SAR116_0337	1.318e-49	183.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2U67Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
SRR25158527_k127_3885661_2	1227457.C451_06360	6.507e-19	97.0	COG0697@1|root,arCOG00272@2157|Archaea,2XVSM@28890|Euryarchaeota,23S7J@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_3885661_1	313612.L8106_13405	1.675e-43	166.0	COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria,1HHEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SRR25158527_k127_3885661_3	395961.Cyan7425_4448	0.0007843	43.0	COG1446@1|root,COG1446@2|Bacteria,1G4NK@1117|Cyanobacteria,3KJGX@43988|Cyanothece	1117|Cyanobacteria	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
SRR25158527_k127_3890831_0	1504672.669783786	1.831e-142	459.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,4ACKS@80864|Comamonadaceae	28216|Betaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
SRR25158527_k127_3890831_1	1095769.CAHF01000011_gene2300	2.15e-64	224.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2W98D@28216|Betaproteobacteria,476N1@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158527_k127_3905294_1	318424.EU78_28725	7.853e-83	287.0	COG0673@1|root,COG0673@2|Bacteria,2HQ7W@201174|Actinobacteria,23722@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158527_k127_3905294_0	627192.SLG_34970	1.275e-122	406.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske (2Fe-2S) domain-containing protein	-	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
SRR25158527_k127_3914771_1	1313265.JNIE01000003_gene1192	3.704e-09	64.0	COG1734@1|root,COG1734@2|Bacteria,2G5AI@200783|Aquificae	200783|Aquificae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158527_k127_3914771_0	330214.NIDE2263	3.07e-130	423.0	COG0542@1|root,COG0542@2|Bacteria,3J0AV@40117|Nitrospirae	40117|Nitrospirae	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158527_k127_3915212_0	331113.SNE_B24410	6.678e-224	704.0	COG0058@1|root,COG0058@2|Bacteria,2JFEH@204428|Chlamydiae	204428|Chlamydiae	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SRR25158527_k127_3915390_0	330214.NIDE1585	2.886e-136	448.0	COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae	2|Bacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_3915390_1	452637.Oter_2405	6.373e-06	49.0	COG2204@1|root,COG4251@1|root,COG2204@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K07649,ko:K20971	ko02020,ko02025,map02020,map02025	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA,Response_reg
SRR25158527_k127_3917031_1	443144.GM21_2259	4.57e-68	237.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
SRR25158527_k127_3917031_2	338966.Ppro_1292	8.034e-49	181.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SRR25158527_k127_3917031_0	429009.Adeg_1157	1.567e-171	550.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,42EWK@68295|Thermoanaerobacterales	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158527_k127_3917390_1	387631.Asulf_01856	4.049e-106	368.0	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota	28890|Euryarchaeota	C	aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
SRR25158527_k127_3917390_3	1117108.PAALTS15_25814	3.356e-16	90.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26TAX@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	ytlA	GO:0003674,GO:0005215	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_3917390_0	247490.KSU1_C0515	1.465e-143	463.0	COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes	203682|Planctomycetes	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_3917390_2	1229909.NSED_06280	7.32e-35	134.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158527_k127_3917890_2	345341.KUTG_09776	1.291e-11	73.0	COG0715@1|root,COG0715@2|Bacteria,2IBS1@201174|Actinobacteria	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_3917890_0	1380394.JADL01000004_gene5881	1.358e-156	503.0	COG2114@1|root,COG2114@2|Bacteria,1QTFI@1224|Proteobacteria,2TRNP@28211|Alphaproteobacteria,2JQC8@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158527_k127_3917890_1	935840.JAEQ01000009_gene1332	1.43e-145	480.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,43GZZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_3917890_3	1045858.Bint_2163	1.923e-08	62.0	COG0500@1|root,COG2226@2|Bacteria,2J973@203691|Spirochaetes	203691|Spirochaetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158527_k127_392319_0	1267534.KB906754_gene2819	2.479e-66	229.0	29FX8@1|root,302UX@2|Bacteria,3Y7TV@57723|Acidobacteria,2JMXK@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_392319_2	189753.AXAS01000041_gene2534	2.485e-24	109.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRR25158527_k127_392319_1	330214.NIDE1515	1.288e-36	139.0	COG0312@1|root,COG0312@2|Bacteria,3J0P7@40117|Nitrospirae	40117|Nitrospirae	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158527_k127_3933249_0	56107.Cylst_1620	2.186e-70	248.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
SRR25158527_k127_3933249_1	318586.Pden_3216	8.152e-54	201.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2TXTS@28211|Alphaproteobacteria,2PY7W@265|Paracoccus	28211|Alphaproteobacteria	C	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	MA20_29235	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158527_k127_3936289_2	1144275.COCOR_07073	4.631e-26	126.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1N4IM@1224|Proteobacteria,437ZC@68525|delta/epsilon subdivisions,2WZWU@28221|Deltaproteobacteria,2YUXT@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SRR25158527_k127_3936289_0	1499967.BAYZ01000095_gene4251	3.729e-90	329.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SRR25158527_k127_3936289_1	324602.Caur_3411	1.403e-64	233.0	COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158527_k127_3937021_0	316058.RPB_4416	4.278e-194	628.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158527_k127_3937021_1	36080.S2IXN4	7.732e-07	52.0	COG0454@1|root,KOG3216@2759|Eukaryota,3A3YH@33154|Opisthokonta,3P4H0@4751|Fungi,1GUHR@112252|Fungi incertae sedis	4751|Fungi	E	Acetyltransferase (GNAT) domain	ats1	GO:0003674,GO:0003824,GO:0004145,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158527_k127_3941296_1	1449126.JQKL01000017_gene2765	2.458e-85	292.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,2687X@186813|unclassified Clostridiales	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SRR25158527_k127_3941296_6	880072.Desac_2618	6.465e-14	79.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MSCN@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
SRR25158527_k127_3941296_4	1158318.ATXC01000001_gene854	5.837e-34	135.0	COG1610@1|root,COG1610@2|Bacteria,2G4V2@200783|Aquificae	200783|Aquificae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158527_k127_3941296_5	404589.Anae109_0759	2.483e-22	98.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SRR25158527_k127_3941296_3	292459.STH2458	4.085e-49	187.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SRR25158527_k127_3941296_2	243231.GSU1420	8.981e-78	271.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,43S7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158527_k127_3941296_0	398767.Glov_2235	1.248e-224	715.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158527_k127_3941779_0	1122915.AUGY01000118_gene6538	2.106e-103	349.0	COG4638@1|root,COG4638@2|Bacteria,1UZWG@1239|Firmicutes,4HBGQ@91061|Bacilli,26VC1@186822|Paenibacillaceae	91061|Bacilli	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158527_k127_3941782_1	402777.KB235898_gene5603	1.55e-07	57.0	COG1547@1|root,COG1547@2|Bacteria,1G7QG@1117|Cyanobacteria,1HBGH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158527_k127_3941782_0	338963.Pcar_0091	1.989e-177	585.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,43SCA@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TRCF	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158527_k127_395026_3	1173263.Syn7502_03004	6.696e-13	76.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_395026_2	767817.Desgi_3969	1.745e-34	140.0	COG2068@1|root,COG2068@2|Bacteria,1UMIC@1239|Firmicutes,24M9Z@186801|Clostridia	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158527_k127_395026_0	1547437.LL06_00335	1.558e-85	293.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,43IZ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	4.1.1.55	ko:K04102	ko00624,ko01100,ko01120,map00624,map01100,map01120	M00623	R01635,R05375	RC00390	ko00000,ko00001,ko00002,ko01000	-	-	-	NMT1
SRR25158527_k127_395026_1	762376.AXYL_03732	3.74e-69	242.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNP8@28216|Betaproteobacteria,3T1Y0@506|Alcaligenaceae	28216|Betaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158527_k127_3950324_0	330214.NIDE1868	2.579e-123	402.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3J0UH@40117|Nitrospirae	40117|Nitrospirae	H	Pterin binding enzyme	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
SRR25158527_k127_3950324_1	1380356.JNIK01000013_gene4137	2.567e-11	70.0	2CJXB@1|root,2ZIFC@2|Bacteria,2H9YF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_3952115_0	1382356.JQMP01000004_gene231	5.574e-82	287.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,27XNE@189775|Thermomicrobia	189775|Thermomicrobia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158527_k127_3952115_4	926550.CLDAP_39560	7.772e-28	117.0	COG1975@1|root,COG1975@2|Bacteria	2|Bacteria	O	molybdopterin cofactor binding	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158527_k127_3952115_2	768704.Desmer_1179	1.058e-45	177.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,2617B@186807|Peptococcaceae	186801|Clostridia	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158527_k127_3952115_5	76114.ebA3131	8.766e-17	85.0	COG1339@1|root,COG1339@2|Bacteria,1NFGP@1224|Proteobacteria,2W3D2@28216|Betaproteobacteria,2KZ1I@206389|Rhodocyclales	206389|Rhodocyclales	HK	Domain of unknown function DUF120	-	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase
SRR25158527_k127_3952115_1	571.MC52_28310	2.913e-74	256.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2311,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573	Flavoprotein
SRR25158527_k127_3952115_3	313612.L8106_30505	2.777e-30	124.0	COG1304@1|root,COG1304@2|Bacteria,1G2KC@1117|Cyanobacteria,1H8I2@1150|Oscillatoriales	1117|Cyanobacteria	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SRR25158527_k127_3961514_0	592015.HMPREF1705_00165	1.223e-98	332.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,3TA4P@508458|Synergistetes	508458|Synergistetes	G	PFAM glycosyl transferase family 20	-	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
SRR25158527_k127_3961622_0	1120973.AQXL01000117_gene375	5.479e-106	356.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SRR25158527_k127_3961622_1	671143.DAMO_1685	2.215e-19	97.0	COG3945@1|root,COG4309@1|root,COG3945@2|Bacteria,COG4309@2|Bacteria,2NRHJ@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF2249,Hemerythrin
SRR25158527_k127_3980710_2	1194972.MVAC_28843	6.699e-08	59.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria,235A3@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158527_k127_3980710_1	1038860.AXAP01000097_gene5007	9.028e-31	134.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_3980710_0	264198.Reut_B5286	3.206e-65	236.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP7Y@28216|Betaproteobacteria,1KBE5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_3981979_1	1117314.PCIT_16245	3.991e-18	94.0	COG3766@1|root,COG3766@2|Bacteria,1Q8XV@1224|Proteobacteria,1S8G4@1236|Gammaproteobacteria,2Q4JZ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SRR25158527_k127_3981979_0	1226322.HMPREF1545_03113	1.234e-49	185.0	COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes	1239|Firmicutes	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
SRR25158527_k127_3990505_1	237368.SCABRO_02536	2.486e-18	88.0	COG2212@1|root,COG2212@2|Bacteria,2J1KY@203682|Planctomycetes	203682|Planctomycetes	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
SRR25158527_k127_3990505_0	383372.Rcas_1774	4.536e-36	141.0	COG1320@1|root,COG1320@2|Bacteria,2G72M@200795|Chloroflexi,377VX@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
SRR25158527_k127_3990505_2	452637.Oter_2251	2.166e-14	82.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
SRR25158527_k127_3998674_1	1463917.JODC01000007_gene7331	2.636e-18	97.0	COG0477@1|root,COG2814@2|Bacteria,2GM2G@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K05548	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4,Sugar_tr
SRR25158527_k127_3998674_0	744872.Spica_0618	8.062e-21	96.0	COG1917@1|root,COG1917@2|Bacteria,2JAJW@203691|Spirochaetes	203691|Spirochaetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_400423_1	469383.Cwoe_1854	2.352e-22	100.0	COG4034@1|root,COG4034@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF1152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1152
SRR25158527_k127_400423_0	1380394.JADL01000021_gene1881	3.628e-70	244.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_400423_2	1122222.AXWR01000003_gene1343	5.823e-08	60.0	COG2267@1|root,COG2267@2|Bacteria,1WJIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Alpha beta hydrolase	-	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,CMD
SRR25158527_k127_4006370_1	401526.TcarDRAFT_1060	2.121e-36	154.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4H2AI@909932|Negativicutes	909932|Negativicutes	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158527_k127_4006370_0	113395.AXAI01000007_gene1458	1.461e-62	220.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
SRR25158527_k127_401784_1	572546.Arcpr_1280	2.534e-12	68.0	COG3635@1|root,arCOG01696@2157|Archaea,2XU1U@28890|Euryarchaeota,245SI@183980|Archaeoglobi	183980|Archaeoglobi	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158527_k127_401784_0	167555.NATL1_15361	7.029e-69	252.0	COG0460@1|root,COG0460@2|Bacteria,1G0WN@1117|Cyanobacteria,1MKRU@1212|Prochloraceae	1117|Cyanobacteria	E	Homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SRR25158527_k127_4019883_2	44454.NF84_12460	1.069e-29	129.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_4019883_3	1206739.BAGJ01000103_gene2038	6.216e-19	98.0	COG0715@1|root,COG0715@2|Bacteria,2HHNY@201174|Actinobacteria,4FZGF@85025|Nocardiaceae	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_4019883_4	743719.PaelaDRAFT_0962	8.384e-16	89.0	COG0715@1|root,COG0715@2|Bacteria,1TRDC@1239|Firmicutes,4HBAA@91061|Bacilli,26UYR@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_4019883_0	93220.LV28_12030	5.282e-63	231.0	COG1960@1|root,COG1960@2|Bacteria,1PPFP@1224|Proteobacteria,2W9GQ@28216|Betaproteobacteria,1KBRH@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_4019883_1	1173263.Syn7502_03004	2.336e-37	153.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_4025857_0	158189.SpiBuddy_0412	1.276e-38	158.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_4025857_1	1246995.AFR_31335	5.146e-30	134.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4DAI6@85008|Micromonosporales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158527_k127_4028360_2	511062.GU3_02140	5.633e-06	53.0	COG4967@1|root,COG4967@2|Bacteria,1N992@1224|Proteobacteria	1224|Proteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SRR25158527_k127_4028360_1	671143.DAMO_2487	9.888e-51	183.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	lspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SRR25158527_k127_4028360_0	472759.Nhal_0440	1.589e-56	204.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WWYV@135613|Chromatiales	135613|Chromatiales	NU	Type II secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
SRR25158527_k127_4035130_3	485915.Dret_1459	2.688e-14	74.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2M8AT@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158527_k127_4035130_1	330214.NIDE1005	8.181e-140	453.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158527_k127_4035130_0	56780.SYN_00911	5.601e-145	466.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2MQ48@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158527_k127_4035130_2	1009370.ALO_03441	8.452e-55	199.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4H2Z4@909932|Negativicutes	909932|Negativicutes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158527_k127_404124_0	285535.JOEY01000075_gene5963	5.348e-78	274.0	COG2141@1|root,COG2141@2|Bacteria,2GITK@201174|Actinobacteria	201174|Actinobacteria	C	Monooxygenase	limB	-	1.14.13.107	ko:K14733	ko00903,map00903	-	R06398,R09385,R09389,R09393	RC01506	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158527_k127_4047652_0	443143.GM18_0728	1.873e-289	895.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter related	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
SRR25158527_k127_4047652_2	525904.Tter_2679	5.551e-65	239.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_4047652_1	56107.Cylst_1620	3.816e-76	269.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
SRR25158527_k127_4050049_0	639282.DEFDS_1169	1.652e-183	589.0	COG0209@1|root,COG0209@2|Bacteria,2GERH@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
SRR25158527_k127_4062314_2	243231.GSU0874	3.714e-17	96.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42URI@68525|delta/epsilon subdivisions,2WQ69@28221|Deltaproteobacteria,43U4E@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971,DUF748
SRR25158527_k127_4062314_4	83406.HDN1F_29070	0.0005285	46.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Excisionase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158527_k127_4062314_1	243090.RB2970	3.107e-47	177.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
SRR25158527_k127_4062314_3	401526.TcarDRAFT_0816	5.165e-14	74.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4H5YN@909932|Negativicutes	909932|Negativicutes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	-	-	-	-	-	-	-	-	-	MttA_Hcf106
SRR25158527_k127_4062314_0	671143.DAMO_3115	5.918e-49	183.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR25158527_k127_4064151_2	1123501.KB902283_gene2287	9.155e-34	142.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TRAP transporter solute receptor TAXI family protein	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
SRR25158527_k127_4064151_1	314271.RB2654_18041	1.901e-39	160.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TRAP transporter solute receptor TAXI family protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158527_k127_4064151_0	1150398.JIBJ01000002_gene1058	8.716e-82	277.0	COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria,1W8SE@1268|Micrococcaceae	201174|Actinobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE2	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158527_k127_4087989_1	1379698.RBG1_1C00001G0637	1.082e-83	284.0	COG0677@1|root,COG0677@2|Bacteria,2NNQ1@2323|unclassified Bacteria	2|Bacteria	M	UDP binding domain	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158527_k127_4087989_0	330214.NIDE0623	4.383e-296	943.0	COG0653@1|root,COG0653@2|Bacteria,3J0E5@40117|Nitrospirae	40117|Nitrospirae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158527_k127_4089567_0	1123368.AUIS01000038_gene37	3.009e-77	267.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,1S4YT@1236|Gammaproteobacteria,2ND78@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158527_k127_4089567_1	1172179.AUKV01000009_gene4532	7.024e-27	121.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158527_k127_4089567_2	869210.Marky_1921	5.391e-22	100.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158527_k127_4090099_1	671143.DAMO_2495	9.624e-202	644.0	COG1132@1|root,COG1132@2|Bacteria,2NNN4@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter transmembrane region	mdlA	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158527_k127_4090099_0	671143.DAMO_2494	1.797e-232	733.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158527_k127_4090099_2	234267.Acid_4681	2.233e-10	61.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
SRR25158527_k127_4097444_1	177439.DP2188	6.743e-121	395.0	COG0041@1|root,COG0151@1|root,COG0041@2|Bacteria,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
SRR25158527_k127_4097444_0	398767.Glov_2760	8.709e-197	626.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158527_k127_4098227_0	631454.N177_3820	9.245e-115	383.0	COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,1JQCV@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158527_k127_4098227_1	1123023.JIAI01000018_gene2505	8.981e-11	63.0	COG0715@1|root,COG0715@2|Bacteria,2HZMX@201174|Actinobacteria,4E025@85010|Pseudonocardiales	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_4102835_2	378806.STAUR_5573	5.537e-29	119.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria,2YYFC@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SRR25158527_k127_4102835_0	243231.GSU2264	8.71e-88	297.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria,43RXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SRR25158527_k127_4102835_1	243231.GSU2265	2.482e-39	149.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,43UKW@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SRR25158527_k127_4106882_0	105559.Nwat_0059	6.279e-83	284.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RQ0G@1236|Gammaproteobacteria,1WXEX@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158527_k127_4106882_1	1410609.JHVB01000001_gene1799	3.002e-46	171.0	COG0389@1|root,COG0389@2|Bacteria,2J5NZ@203691|Spirochaetes	203691|Spirochaetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158527_k127_4110705_0	448385.sce4318	7.069e-17	87.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158527_k127_4110705_1	1120949.KB903303_gene6702	4.913e-15	89.0	COG1994@1|root,COG1994@2|Bacteria,2IBWH@201174|Actinobacteria,4DB7M@85008|Micromonosporales	201174|Actinobacteria	T	ATPase activity	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	AhpC-TSA,FHA,Yop-YscD_cpl,cNMP_binding
SRR25158527_k127_4110705_2	1231391.AMZF01000020_gene1928	0.0006879	45.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_4112978_1	313612.L8106_00675	1.253e-12	78.0	COG0265@1|root,COG4783@1|root,COG0265@2|Bacteria,COG4783@2|Bacteria,1G0BH@1117|Cyanobacteria,1H94Z@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_14
SRR25158527_k127_4112978_0	525897.Dbac_2942	1.258e-67	238.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_4113736_1	237368.SCABRO_01842	3.129e-40	156.0	COG1047@1|root,COG1047@2|Bacteria,2J1AR@203682|Planctomycetes	203682|Planctomycetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
SRR25158527_k127_4113736_0	56780.SYN_00042	6.74e-71	249.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42QVM@68525|delta/epsilon subdivisions,2WN3E@28221|Deltaproteobacteria,2MRIY@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sir2 family	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158527_k127_4116628_4	228410.NE1434	0.0008789	47.0	COG5424@1|root,COG5424@2|Bacteria,1PVPF@1224|Proteobacteria,2VKFF@28216|Betaproteobacteria,37201@32003|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM TENA THI-4 protein Coenzyme PQQ biosynthesis protein C	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158527_k127_4116628_2	675635.Psed_2624	5.065e-64	229.0	COG1878@1|root,COG1878@2|Bacteria,2I66K@201174|Actinobacteria,4E76K@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158527_k127_4116628_1	266265.Bxe_B2813	8.548e-69	244.0	COG0329@1|root,COG0329@2|Bacteria,1NQJ0@1224|Proteobacteria	1224|Proteobacteria	EM	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_4116628_0	1128421.JAGA01000002_gene1959	5.598e-112	370.0	COG0446@1|root,COG0446@2|Bacteria,2NPPU@2323|unclassified Bacteria	2|Bacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158527_k127_411762_4	269799.Gmet_0981	3.374e-53	191.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria,43SNK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158527_k127_411762_0	404380.Gbem_1556	1.604e-109	365.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria,43TT5@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158527_k127_411762_5	1449126.JQKL01000014_gene2984	5.447e-36	142.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
SRR25158527_k127_411762_1	243231.GSU2027	1.671e-76	261.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,43U6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
SRR25158527_k127_411762_3	338966.Ppro_2028	9.296e-69	238.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,43U6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
SRR25158527_k127_411762_2	246197.MXAN_5772	2.93e-73	262.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SRR25158527_k127_4155642_0	1207063.P24_04410	1.851e-59	216.0	COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,2JVWG@204441|Rhodospirillales	204441|Rhodospirillales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158527_k127_4155642_1	882083.SacmaDRAFT_2714	8.48e-50	183.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4E5JW@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158527_k127_4156653_1	645991.Sgly_1020	2.933e-09	68.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_4156653_0	298654.FraEuI1c_2811	1.036e-58	212.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_4159948_0	1463855.JOHV01000001_gene1701	3.104e-90	306.0	COG4638@1|root,COG4638@2|Bacteria,2HJQP@201174|Actinobacteria	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158527_k127_4159948_1	330084.JNYZ01000011_gene7454	1.523e-39	159.0	COG0715@1|root,COG0715@2|Bacteria,2HZMX@201174|Actinobacteria,4E025@85010|Pseudonocardiales	201174|Actinobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_4159948_2	314278.NB231_08798	4.663e-26	113.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,1RN07@1236|Gammaproteobacteria,1X0B8@135613|Chromatiales	135613|Chromatiales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_2
SRR25158527_k127_4160998_2	1231391.AMZF01000094_gene96	7.725e-11	64.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2VMW1@28216|Betaproteobacteria,3T349@506|Alcaligenaceae	28216|Betaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	4.1.1.55	ko:K04102	ko00624,ko01100,ko01120,map00624,map01100,map01120	M00623	R01635,R05375	RC00390	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158527_k127_4160998_1	1038860.AXAP01000097_gene5007	2.902e-11	75.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,3K1ZF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_4160998_0	455632.SGR_354	9.732e-33	138.0	COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria	201174|Actinobacteria	Q	Catalyzes the conversion of maleate to fumarate	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158527_k127_4164746_0	1382359.JIAL01000001_gene1757	6.499e-174	557.0	COG0034@1|root,COG0034@2|Bacteria,3Y3RG@57723|Acidobacteria,2JHXM@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158527_k127_4164746_1	1379698.RBG1_1C00001G0338	2.563e-62	220.0	COG0046@1|root,COG0046@2|Bacteria,2NNPS@2323|unclassified Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158527_k127_4165748_0	1306990.BARG01000030_gene3384	2.704e-89	308.0	COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria	201174|Actinobacteria	Q	Pfam Cupin	-	-	1.13.11.38,1.13.11.4	ko:K00450,ko:K11948	ko00350,ko00624,ko01100,ko01120,map00350,map00624,map01100,map01120	-	R02656,R07657	RC00764,RC00937	ko00000,ko00001,ko01000	-	-	-	Cupin_2
SRR25158527_k127_4165748_1	296591.Bpro_1629	3.144e-56	215.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,4ACAF@80864|Comamonadaceae	28216|Betaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
SRR25158527_k127_4168008_0	1121918.ARWE01000001_gene633	9.994e-34	132.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,43T5C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158527_k127_4168008_3	1122612.AUBA01000016_gene688	5.427e-12	78.0	COG2271@1|root,COG2271@2|Bacteria,1QWH9@1224|Proteobacteria,2U9UB@28211|Alphaproteobacteria,2KEIM@204457|Sphingomonadales	204457|Sphingomonadales	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158527_k127_4168008_2	1206725.BAFU01000021_gene3401	1.071e-13	73.0	COG1872@1|root,COG1872@2|Bacteria,2GRF6@201174|Actinobacteria,4G34J@85025|Nocardiaceae	201174|Actinobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158527_k127_4168008_1	717774.Marme_0653	1.256e-20	96.0	COG0517@1|root,COG0517@2|Bacteria,1N13S@1224|Proteobacteria,1SA4N@1236|Gammaproteobacteria,1XM8B@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158527_k127_4169742_0	243231.GSU1820	1.515e-217	705.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
SRR25158527_k127_4169742_2	439235.Dalk_0825	1.838e-86	295.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2MHZH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158527_k127_4169742_3	1485545.JQLW01000009_gene160	1.094e-66	233.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase M50	MA20_27160	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158527_k127_4169742_1	335543.Sfum_0682	1.073e-136	441.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2MQAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	TIGRFAM Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158527_k127_4169742_4	338963.Pcar_1299	1.842e-50	188.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SRR25158527_k127_4176544_1	1122917.KB899671_gene4389	3.251e-67	252.0	COG0471@1|root,COG0664@1|root,COG0471@2|Bacteria,COG0664@2|Bacteria,1U26G@1239|Firmicutes,4HEVG@91061|Bacilli	91061|Bacilli	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Na_sulph_symp,cNMP_binding
SRR25158527_k127_4176544_0	330214.NIDE2020	5.001e-70	244.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_4185156_2	1121440.AUMA01000007_gene1048	4.721e-45	176.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2M927@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_4185156_0	522306.CAP2UW1_2480	1.981e-102	351.0	2B3X8@1|root,31WM6@2|Bacteria,1RFRT@1224|Proteobacteria,2VRRY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
SRR25158527_k127_4185156_1	522306.CAP2UW1_2481	2.766e-50	183.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
SRR25158527_k127_4193862_2	1121085.AUCI01000024_gene176	0.000686	44.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_4193862_1	765698.Mesci_2875	1.568e-13	81.0	COG0715@1|root,COG0715@2|Bacteria,1MVUJ@1224|Proteobacteria,2U2DS@28211|Alphaproteobacteria,43MG7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_4193862_0	1118054.CAGW01000075_gene3263	1.395e-51	192.0	COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158527_k127_4195040_2	671143.DAMO_1165	5.06e-31	124.0	COG0843@1|root,COG0843@2|Bacteria,2NNTQ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158527_k127_4195040_1	671143.DAMO_1660	4.975e-83	286.0	COG1612@1|root,COG1612@2|Bacteria,2NQ3D@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259,ko:K03110	ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714	M00154,M00335	R07412	RC00769	ko00000,ko00001,ko00002,ko02044,ko03029	3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4	-	-	COX15-CtaA
SRR25158527_k127_4195040_0	671143.DAMO_1659	1.14e-90	314.0	COG0109@1|root,COG0109@2|Bacteria,2NPBW@2323|unclassified Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	iJN746.PP_0110,iSB619.SA_RS05465,iSFxv_1172.SFxv_0410,iYO844.BSU12080	UbiA
SRR25158527_k127_4195048_2	47716.JOFH01000003_gene591	1.106e-07	56.0	COG1917@1|root,COG1917@2|Bacteria,2I3J0@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_4195048_0	469383.Cwoe_4099	1.33e-88	302.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_4195048_1	266264.Rmet_1323	2.336e-13	75.0	COG3193@1|root,COG3193@2|Bacteria,1RH9E@1224|Proteobacteria,2VT15@28216|Betaproteobacteria,1K7X4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158527_k127_4214102_3	1123023.JIAI01000001_gene6358	1.745e-53	200.0	COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria,4E06G@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_4214102_2	318996.AXAZ01000017_gene839	7.956e-55	195.0	2E3CR@1|root,32YC0@2|Bacteria,1N9Q9@1224|Proteobacteria,2UF5B@28211|Alphaproteobacteria,3JYQP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nitrile hydratase beta subunit	MA20_29595	-	-	-	-	-	-	-	-	-	-	-	NHase_beta
SRR25158527_k127_4214102_1	1298867.AUES01000047_gene4240	1.045e-90	304.0	28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,2U3PK@28211|Alphaproteobacteria,3JS7H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	NHase catalyzes the hydration of various nitrile compounds to the corresponding amides	nthB	-	4.2.1.84	ko:K20807	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R04020,R05379,R05596,R07780,R07854	RC00483,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_beta
SRR25158527_k127_4214102_0	1297865.APJD01000026_gene2579	6.49e-98	324.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,3JT2X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Nitrile hydratase, alpha chain	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
SRR25158527_k127_4220359_1	1089553.Tph_c23930	2.621e-62	227.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42HS5@68295|Thermoanaerobacterales	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
SRR25158527_k127_4220359_0	1122917.KB899665_gene3996	1.648e-107	365.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,26TE8@186822|Paenibacillaceae	91061|Bacilli	H	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate	yclC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464	4.1.1.61	ko:K01612,ko:K16874	ko00365,ko00627,ko01120,ko01220,map00365,map00627,map01120,map01220	-	R01238,R10213	RC00391,RC03086	ko00000,ko00001,ko01000	-	-	-	UbiD
SRR25158527_k127_4220359_2	1944.JOAZ01000033_gene146	2.998e-14	84.0	COG0715@1|root,COG0715@2|Bacteria,2HFTU@201174|Actinobacteria,41CZK@629295|Streptomyces griseus group	2|Bacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_4223753_0	76114.p2A120	2.891e-97	329.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_4223753_2	1123023.JIAI01000001_gene6575	8.409e-07	59.0	COG5424@1|root,COG5424@2|Bacteria,2I9SS@201174|Actinobacteria,4E05W@85010|Pseudonocardiales	201174|Actinobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
SRR25158527_k127_4223753_1	443152.MDG893_15467	8.234e-32	133.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_4225882_0	671143.DAMO_2824	1.206e-149	482.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
SRR25158527_k127_4225882_1	1121405.dsmv_3242	1.486e-37	148.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2MMDF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SRR25158527_k127_4228502_6	240015.ACP_1875	4.881e-25	108.0	COG0415@1|root,COG0415@2|Bacteria,3Y31R@57723|Acidobacteria,2JHWQ@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
SRR25158527_k127_4228502_0	1123242.JH636434_gene5621	2.279e-198	628.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SRR25158527_k127_4228502_4	479434.Sthe_2075	7.002e-59	217.0	COG1647@1|root,COG1647@2|Bacteria,2G909@200795|Chloroflexi,27YHB@189775|Thermomicrobia	189775|Thermomicrobia	S	Serine hydrolase (FSH1)	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158527_k127_4228502_7	1192034.CAP_8919	4.205e-10	70.0	2DYHI@1|root,349R4@2|Bacteria,1P45P@1224|Proteobacteria,432Q7@68525|delta/epsilon subdivisions,2WY40@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_4228502_3	479434.Sthe_2076	2.473e-102	345.0	COG1215@1|root,COG1215@2|Bacteria,2GBNF@200795|Chloroflexi,27YBR@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase family 21	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158527_k127_4228502_5	479434.Sthe_2077	6.818e-54	198.0	COG0204@1|root,COG2324@1|root,COG0204@2|Bacteria,COG2324@2|Bacteria,2G7BI@200795|Chloroflexi,27Y4M@189775|Thermomicrobia	189775|Thermomicrobia	I	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Caroten_synth
SRR25158527_k127_4228502_2	203124.Tery_3574	1.534e-109	367.0	COG4638@1|root,COG4638@2|Bacteria,1G22J@1117|Cyanobacteria,1H8JV@1150|Oscillatoriales	1117|Cyanobacteria	P	large terminal subunit'	cbaB	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158527_k127_4228502_1	1192034.CAP_6809	1.085e-137	453.0	COG3349@1|root,COG3349@2|Bacteria,1RAVN@1224|Proteobacteria,433WH@68525|delta/epsilon subdivisions,2X3VQ@28221|Deltaproteobacteria,2YX9K@29|Myxococcales	28221|Deltaproteobacteria	Q	FAD dependent oxidoreductase	-	-	-	ko:K09879	ko00906,map00906	-	R07541,R07560,R07857,R07858	RC01901,RC01965	ko00000,ko00001	-	-	-	Amino_oxidase
SRR25158527_k127_4228515_0	1121472.AQWN01000011_gene1225	2.807e-199	646.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
SRR25158527_k127_4242679_1	1229172.JQFA01000004_gene848	9.96e-81	273.0	COG2307@1|root,COG2307@2|Bacteria,1G05F@1117|Cyanobacteria,1H8SU@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial domain of	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
SRR25158527_k127_4242679_0	521674.Plim_1493	1.663e-230	721.0	COG2308@1|root,COG2308@2|Bacteria,2IXE6@203682|Planctomycetes	203682|Planctomycetes	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
SRR25158527_k127_4248100_2	404380.Gbem_2452	2.788e-35	136.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,42U6P@68525|delta/epsilon subdivisions,2WQ00@28221|Deltaproteobacteria,43V75@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	SMART HNH nuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_5
SRR25158527_k127_4248100_0	404589.Anae109_1864	1.687e-133	433.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
SRR25158527_k127_4248100_1	1304883.KI912532_gene2389	1.3e-51	186.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KWIF@206389|Rhodocyclales	206389|Rhodocyclales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158527_k127_4250189_1	1169161.KB897726_gene1441	3.883e-23	109.0	COG3473@1|root,COG3473@2|Bacteria,2HRMA@201174|Actinobacteria	201174|Actinobacteria	Q	Catalyzes the conversion of maleate to fumarate	-	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
SRR25158527_k127_4250189_0	1003200.AXXA_25600	1.945e-69	246.0	COG2159@1|root,COG2159@2|Bacteria,1R7D7@1224|Proteobacteria,2VNK3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_425286_1	502025.Hoch_4707	1.02e-51	192.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,434HT@68525|delta/epsilon subdivisions,2WYV2@28221|Deltaproteobacteria,2Z0PY@29|Myxococcales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158527_k127_425286_2	1123376.AUIU01000014_gene616	4.025e-18	89.0	2EK9R@1|root,33E01@2|Bacteria,3J1B5@40117|Nitrospirae	40117|Nitrospirae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_425286_0	1041146.ATZB01000008_gene2208	5.596e-54	198.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,4B7AF@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	dienelactone hydrolase	dlhH	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_4260294_0	756067.MicvaDRAFT_3324	2.637e-64	233.0	COG4301@1|root,COG4301@2|Bacteria,1G2JI@1117|Cyanobacteria,1H739@1150|Oscillatoriales	1117|Cyanobacteria	S	conserved protein (DUF2260)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SRR25158527_k127_4260294_1	1206735.BAGG01000110_gene4710	7.517e-27	114.0	COG3239@1|root,COG3239@2|Bacteria,2I8NB@201174|Actinobacteria,4G0AE@85025|Nocardiaceae	201174|Actinobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
SRR25158527_k127_4262350_0	313606.M23134_04296	1.385e-63	231.0	28J0S@1|root,2Z8XX@2|Bacteria,4P2J4@976|Bacteroidetes,47X8E@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_4262350_1	1121124.JNIX01000008_gene2551	2.117e-56	209.0	COG0596@1|root,COG0596@2|Bacteria,1Q6ET@1224|Proteobacteria,2URHM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	3.3.2.9	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_6
SRR25158527_k127_4262350_2	111780.Sta7437_2730	9.177e-17	90.0	COG0457@1|root,COG0457@2|Bacteria,1G3MN@1117|Cyanobacteria,3VKXC@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
SRR25158527_k127_4262504_0	485913.Krac_10287	5.823e-126	412.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158527_k127_4262504_1	886293.Sinac_1445	6.706e-32	130.0	COG0247@1|root,COG0247@2|Bacteria,2IXBR@203682|Planctomycetes	203682|Planctomycetes	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
SRR25158527_k127_4266559_0	795666.MW7_3072	1.399e-85	288.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VJ2Z@28216|Betaproteobacteria,1K093@119060|Burkholderiaceae	28216|Betaproteobacteria	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
SRR25158527_k127_4266559_1	1131269.AQVV01000006_gene529	1.829e-68	239.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	oppB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158527_k127_426924_1	1120936.KB907220_gene1952	3.984e-89	301.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4ENN5@85012|Streptosporangiales	201174|Actinobacteria	E	TOBE domain	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158527_k127_426924_0	1231391.AMZF01000063_gene1102	6.564e-156	510.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VMRE@28216|Betaproteobacteria,3T2HR@506|Alcaligenaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158527_k127_426924_2	1231391.AMZF01000068_gene2180	2.094e-26	116.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_4284438_0	710686.Mycsm_03169	8.615e-26	111.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_4284438_1	861299.J421_3007	2.74e-21	94.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_4287754_0	1131269.AQVV01000006_gene491	2.595e-88	298.0	COG0649@1|root,COG0649@2|Bacteria	2|Bacteria	C	NAD binding	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
SRR25158527_k127_4287754_1	1131269.AQVV01000018_gene1932	1.771e-45	170.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
SRR25158527_k127_4287754_2	243231.GSU0338	3.39e-36	140.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42W9X@68525|delta/epsilon subdivisions,2WSEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA-1	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158527_k127_4287754_3	1297865.APJD01000021_gene3071	2.774e-06	52.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2V7DS@28211|Alphaproteobacteria,3JXI6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,SBP_bac_6
SRR25158527_k127_4288666_0	96561.Dole_0153	3.653e-73	259.0	28M0D@1|root,2ZAFE@2|Bacteria,1R6YH@1224|Proteobacteria,42NPF@68525|delta/epsilon subdivisions,2WM7K@28221|Deltaproteobacteria,2MIG7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
SRR25158527_k127_4288666_1	1453505.JASY01000003_gene2164	3.866e-29	125.0	COG0400@1|root,COG0400@2|Bacteria,4NF4I@976|Bacteroidetes,1HXVK@117743|Flavobacteriia,2NTH7@237|Flavobacterium	976|Bacteroidetes	S	phospholipase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
SRR25158527_k127_4290676_0	933262.AXAM01000042_gene1821	7.224e-53	207.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2MJ19@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
SRR25158527_k127_4290676_1	472759.Nhal_3648	9.54e-34	147.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WVZW@135613|Chromatiales	135613|Chromatiales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
SRR25158527_k127_4292845_1	375286.mma_0772	1.945e-46	176.0	COG3964@1|root,COG3964@2|Bacteria,1MVC7@1224|Proteobacteria,2VVEK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158527_k127_4292845_0	491915.Aflv_0216	2.05e-132	432.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,21W23@150247|Anoxybacillus	91061|Bacilli	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	-	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158527_k127_4296002_0	1337936.IJ00_09285	5.202e-19	90.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1HKPN@1161|Nostocales	1117|Cyanobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_4296002_1	1144310.PMI07_005585	6.518e-16	90.0	COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_4302928_3	224914.BMEI1862	7.434e-06	53.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,1J2TP@118882|Brucellaceae	28211|Alphaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158527_k127_4302928_0	1304880.JAGB01000001_gene261	6.727e-85	297.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158527_k127_4302928_2	240015.ACP_3407	1.585e-22	105.0	COG1267@1|root,COG1267@2|Bacteria,3Y4T1@57723|Acidobacteria,2JJH6@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
SRR25158527_k127_4302928_1	1301098.PKB_0593	2.159e-67	244.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
SRR25158527_k127_4304809_1	269799.Gmet_3132	1.83e-42	163.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,43SW8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158527_k127_4304809_0	1379698.RBG1_1C00001G0364	7.758e-120	395.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158527_k127_4305210_1	298654.FraEuI1c_2811	1.631e-49	190.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_4305210_0	479434.Sthe_2989	6.261e-69	250.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_4324183_2	335543.Sfum_4057	1.135e-61	218.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2MR0J@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SRR25158527_k127_4324183_0	1267533.KB906733_gene3460	2.016e-108	357.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158527_k127_4324183_1	243231.GSU1113	1.23e-104	349.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SRR25158527_k127_4334429_0	309799.DICTH_0772	2.741e-136	444.0	COG1812@1|root,COG1812@2|Bacteria	2|Bacteria	E	S-adenosylmethionine synthetase (AdoMet synthetase)	metK-2	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
SRR25158527_k127_4334429_1	1131553.JIBI01000004_gene351	1.557e-09	60.0	COG1073@1|root,COG1073@2|Bacteria,1N595@1224|Proteobacteria	1224|Proteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158527_k127_4339471_6	1121439.dsat_1334	4.09e-20	95.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2WRDG@28221|Deltaproteobacteria,2MCE6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158527_k127_4339471_3	1121468.AUBR01000106_gene3110	1.861e-50	188.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,42GBC@68295|Thermoanaerobacterales	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158527_k127_4339471_5	1121405.dsmv_3386	3.09e-35	142.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2WQIY@28221|Deltaproteobacteria,2MK9Q@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158527_k127_4339471_0	1123371.ATXH01000007_gene554	4.202e-127	415.0	COG0462@1|root,COG0462@2|Bacteria,2GGWM@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158527_k127_4339471_4	404589.Anae109_0126	9.979e-37	141.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
SRR25158527_k127_4339471_2	338963.Pcar_2005	9.99e-62	222.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158527_k127_4339471_1	243231.GSU0942	9.503e-74	257.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158527_k127_4339471_7	622637.KE124774_gene2619	4.38e-08	57.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,2UM3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158527_k127_4340729_1	420324.KI912023_gene99	5.231e-37	140.0	COG0715@1|root,COG0715@2|Bacteria,1RJQU@1224|Proteobacteria,2UDJ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
SRR25158527_k127_4340729_0	118168.MC7420_3515	1.567e-79	279.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_4340729_2	1499967.BAYZ01000076_gene809	5.369e-19	94.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	MA20_03535	-	1.1.1.399,1.1.1.95	ko:K00058,ko:K04496	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko04310,ko04330,ko05200,ko05220,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map04310,map04330,map05200,map05220	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158527_k127_4344313_1	631454.N177_1638	9.5e-89	295.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit	cobZ	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
SRR25158527_k127_4344313_0	1123060.JONP01000003_gene489	1.608e-116	386.0	COG1149@1|root,COG1149@2|Bacteria,1QTYV@1224|Proteobacteria,2TTH3@28211|Alphaproteobacteria,2JR3H@204441|Rhodospirillales	204441|Rhodospirillales	C	TIGRFAM CitB domain protein	-	-	-	ko:K13795	-	-	-	-	ko00000	-	-	-	-
SRR25158527_k127_4344313_2	933262.AXAM01000027_gene2082	4.038e-06	52.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,2MIW7@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
SRR25158527_k127_4346353_1	1125863.JAFN01000001_gene568	4.472e-56	199.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
SRR25158527_k127_4346353_2	56780.SYN_02443	1.675e-39	156.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WNB6@28221|Deltaproteobacteria,2MS22@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158527_k127_4346353_0	604354.TSIB_0634	1.942e-83	287.0	COG2423@1|root,arCOG01035@2157|Archaea,2XTTC@28890|Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	ala	GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605	1.4.1.1	ko:K19244	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_4358846_1	671143.DAMO_0699	1.542e-25	107.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
SRR25158527_k127_4358846_0	1121468.AUBR01000021_gene2825	2.712e-235	738.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales	186801|Clostridia	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
SRR25158527_k127_4360270_2	247490.KSU1_C0334	1.079e-19	97.0	COG0589@1|root,COG0589@2|Bacteria,2J042@203682|Planctomycetes	203682|Planctomycetes	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_4360270_0	330214.NIDE1168	5.926e-68	241.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_4360270_1	330214.NIDE3611	2.666e-51	184.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
SRR25158527_k127_4362140_1	671143.DAMO_0980	1.151e-97	325.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158527_k127_4362140_2	765420.OSCT_2907	1.733e-36	143.0	COG2905@1|root,COG2905@2|Bacteria,2G9RT@200795|Chloroflexi,375Z7@32061|Chloroflexia	32061|Chloroflexia	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158527_k127_4362140_0	671143.DAMO_0981	1.814e-154	496.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158527_k127_4366387_0	1123508.JH636442_gene4220	1.095e-191	616.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
SRR25158527_k127_4366387_1	296591.Bpro_4842	4.728e-62	222.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria,4AA42@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158527_k127_4369925_3	635013.TherJR_1377	5.481e-06	56.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158527_k127_4369925_2	762963.HMPREF9056_02682	3.876e-06	52.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,4D61T@85005|Actinomycetales	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158527_k127_4369925_0	706587.Desti_3722	5.733e-142	463.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MQWA@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SRR25158527_k127_4369925_1	1125863.JAFN01000001_gene1427	5.561e-17	83.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158527_k127_4373972_1	479434.Sthe_2196	7.236e-28	118.0	COG1051@1|root,COG1051@2|Bacteria,2G74M@200795|Chloroflexi,27YGS@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158527_k127_4373972_2	671065.MetMK1DRAFT_00008080	3.076e-20	104.0	COG2159@1|root,arCOG01931@2157|Archaea	2157|Archaea	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_4373972_0	391625.PPSIR1_36697	1.46e-110	372.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,2YUUP@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
SRR25158527_k127_4373972_3	502025.Hoch_4484	1.012e-19	90.0	COG5424@1|root,COG5424@2|Bacteria,1Q9R2@1224|Proteobacteria,434J3@68525|delta/epsilon subdivisions,2X8WX@28221|Deltaproteobacteria,2Z0SN@29|Myxococcales	28221|Deltaproteobacteria	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
SRR25158527_k127_4375830_2	880072.Desac_0330	2.903e-18	91.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_4375830_1	1156919.QWC_15089	1.02e-25	125.0	COG2199@1|root,COG2199@2|Bacteria,1R3R8@1224|Proteobacteria,2VJND@28216|Betaproteobacteria,3T58B@506|Alcaligenaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
SRR25158527_k127_4375830_0	32057.KB217478_gene4346	1.133e-56	225.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG5278@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5278@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
SRR25158527_k127_4379311_0	1173027.Mic7113_2967	6.129e-74	261.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	2|Bacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_4379311_2	1231391.AMZF01000006_gene2822	3.248e-15	83.0	COG0662@1|root,COG0662@2|Bacteria,1NUXF@1224|Proteobacteria,2W29X@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_4379311_1	1293048.CBMB010000004_gene1743	3.751e-24	112.0	COG3217@1|root,arCOG04766@2157|Archaea,2Y7HS@28890|Euryarchaeota,241HM@183963|Halobacteria	183963|Halobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158527_k127_43898_1	452637.Oter_3096	2.474e-147	474.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,3K7BN@414999|Opitutae	414999|Opitutae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158527_k127_43898_0	28115.HR11_03470	2.68e-172	552.0	COG1502@1|root,COG1502@2|Bacteria,4NVWC@976|Bacteroidetes,2FZM7@200643|Bacteroidia,2318K@171551|Porphyromonadaceae	976|Bacteroidetes	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SRR25158527_k127_439394_1	146922.JOFU01000020_gene2529	6.874e-56	207.0	COG2355@1|root,COG2355@2|Bacteria	2|Bacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Dickkopf_N,Peptidase_M19,Ricin_B_lectin
SRR25158527_k127_439394_0	1192034.CAP_6251	3.491e-66	235.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_4394903_2	323259.Mhun_1448	0.0007427	42.0	COG2453@1|root,arCOG03413@2157|Archaea	2157|Archaea	T	phosphatase	-	GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc,Y_phosphatase
SRR25158527_k127_4394903_0	1210884.HG799475_gene15269	2.932e-238	747.0	COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158527_k127_4394903_1	432096.XP_003957670.1	2.962e-38	146.0	COG0656@1|root,KOG1577@2759|Eukaryota,38HH0@33154|Opisthokonta,3NU9F@4751|Fungi,3QJT4@4890|Ascomycota,3RTEE@4891|Saccharomycetes,3RYZS@4893|Saccharomycetaceae	4751|Fungi	S	to Saccharomyces cerevisiae YPR1 (YDR368W) and GCY1 (YOR120W)	GCY1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004032,GO:0004033,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005975,GO:0005996,GO:0006950,GO:0006979,GO:0008106,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0033554,GO:0034599,GO:0042221,GO:0042732,GO:0042843,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:0097159,GO:1901363,GO:1901575,GO:1990042	1.1.1.156	ko:K18097	ko00561,ko01100,map00561,map01100	-	R01039	RC00029	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158527_k127_4397484_0	335543.Sfum_3682	5.003e-74	254.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,42TN0@68525|delta/epsilon subdivisions,2WQ75@28221|Deltaproteobacteria,2MQM3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SRR25158527_k127_4397484_1	443152.MDG893_15467	6.023e-48	186.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_4401002_1	1255043.TVNIR_2410	3.967e-81	280.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,1RW61@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158527_k127_4401002_0	706587.Desti_4883	4.804e-90	312.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,42YIF@68525|delta/epsilon subdivisions,2WU4S@28221|Deltaproteobacteria,2MQET@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
SRR25158527_k127_4401002_2	1163617.SCD_n02143	2.515e-47	174.0	COG1230@1|root,COG1230@2|Bacteria,1QUZ5@1224|Proteobacteria,2WGMK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	cation diffusion facilitator family transporter	zitB	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Abhydrolase_6,Cation_efflux
SRR25158527_k127_4402551_2	857087.Metme_2130	9.57e-05	46.0	COG1652@1|root,COG4995@1|root,COG1652@2|Bacteria,COG4995@2|Bacteria,1MZXQ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158527_k127_4402551_1	1247726.MIM_c06320	9.926e-09	67.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,3T1MD@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_4402551_0	1110502.TMO_0232	5.485e-16	78.0	COG2755@1|root,COG2755@2|Bacteria,1RHMJ@1224|Proteobacteria,2UAGU@28211|Alphaproteobacteria,2JUEX@204441|Rhodospirillales	204441|Rhodospirillales	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158527_k127_4406633_2	330214.NIDE2482	9.526e-26	110.0	COG2146@1|root,COG2146@2|Bacteria,3J1E7@40117|Nitrospirae	40117|Nitrospirae	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158527_k127_4406633_0	1242864.D187_001666	4.959e-54	203.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158527_k127_4406633_3	338966.Ppro_3000	9.978e-16	77.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,43URV@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158527_k127_4406633_1	243231.GSU3447	1.258e-28	117.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,43URV@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158527_k127_4412149_0	742821.HMPREF9464_00834	1.71e-124	409.0	COG1053@1|root,COG1053@2|Bacteria,1R0GR@1224|Proteobacteria,2WHU3@28216|Betaproteobacteria,4PRR9@995019|Sutterellaceae	28216|Betaproteobacteria	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
SRR25158527_k127_4413558_0	392499.Swit_4311	1.035e-62	224.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2K5XQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.16	ko:K05713,ko:K15755	ko00360,ko00621,ko01100,ko01120,ko01220,map00360,map00621,map01100,map01120,map01220	M00544,M00545	R04376,R05415,R06788	RC01140,RC01306,RC01364	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	LigB
SRR25158527_k127_4413558_2	1205680.CAKO01000002_gene3085	1.202e-10	65.0	2DPNC@1|root,32UMG@2|Bacteria,1N0XW@1224|Proteobacteria,2UVTT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
SRR25158527_k127_4413558_1	1458275.AZ34_03355	4.162e-22	96.0	COG1073@1|root,COG1073@2|Bacteria,1PJHS@1224|Proteobacteria,2VXXE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100
SRR25158527_k127_4417845_3	630626.EBL_c25760	0.0006651	42.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	gsiC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K13890	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	ic_1306.c0916	BPD_transp_1
SRR25158527_k127_4417845_1	1123060.JONP01000027_gene3502	3.787e-77	267.0	COG0596@1|root,COG0596@2|Bacteria,1N54X@1224|Proteobacteria,2U1C2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158527_k127_4417845_0	195105.CN97_19055	5.781e-132	437.0	COG0747@1|root,COG0747@2|Bacteria,1MWGY@1224|Proteobacteria,2TR73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158527_k127_4417845_2	1173028.ANKO01000224_gene1260	1.036e-05	48.0	COG2159@1|root,COG2159@2|Bacteria,1G3DV@1117|Cyanobacteria,1H964@1150|Oscillatoriales	1117|Cyanobacteria	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_4421130_1	266265.Bxe_C1060	2.895e-106	356.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,1K22A@119060|Burkholderiaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158527_k127_4421130_0	247490.KSU1_A0028	3.409e-170	547.0	COG3666@1|root,COG3666@2|Bacteria,2J1Y1@203682|Planctomycetes	203682|Planctomycetes	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158527_k127_4429346_1	379731.PST_3872	1.99e-68	240.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RRNH@1236|Gammaproteobacteria,1Z238@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	phytoene	crtB	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
SRR25158527_k127_4429346_0	264462.Bd1724	5.611e-221	698.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42NXM@68525|delta/epsilon subdivisions,2MUHZ@213481|Bdellovibrionales,2WJ2I@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	PFAM FAD dependent oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13	ko:K09835,ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04787,R04798,R04800,R07512,R09691,R09692	RC01214,RC01960,RC02088,RC02605	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158527_k127_4429346_2	502025.Hoch_2210	1.965e-51	196.0	COG0142@1|root,COG0142@2|Bacteria,1NXYK@1224|Proteobacteria,430UK@68525|delta/epsilon subdivisions,2WVY1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	-	-	-	-	-	-	-	-	-	-	-	-	polyprenyl_synt
SRR25158527_k127_4429346_3	649747.HMPREF0083_04480	6.716e-07	54.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HNVM@91061|Bacilli,2700T@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRR25158527_k127_4430350_1	443152.MDG893_15260	2.113e-44	173.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_4430350_0	443152.MDG893_15050	9.419e-78	273.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,1RR4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Cyclodeaminase	ocd2	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	iJN746.PP_4431	OCD_Mu_crystall
SRR25158527_k127_4433138_3	338963.Pcar_1690	1.783e-73	263.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria,43SAW@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Bacterial trigger factor protein (TF) C-terminus	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158527_k127_4433138_2	1125863.JAFN01000001_gene3466	5.432e-93	308.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158527_k127_4433138_1	1254432.SCE1572_19005	1.389e-196	619.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158527_k127_4433138_0	290397.Adeh_3350	0.0	1082.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158527_k127_4433594_0	264732.Moth_0463	1.266e-109	376.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,42ETM@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
SRR25158527_k127_4437848_4	1121957.ATVL01000006_gene2738	0.0003006	46.0	COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia	976|Bacteroidetes	N	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SBBP
SRR25158527_k127_4437848_0	748449.Halha_0439	2.669e-134	435.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WAI0@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158527_k127_4437848_1	555088.DealDRAFT_1732	4.905e-131	425.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158527_k127_4437848_3	266779.Meso_3133	0.0001475	44.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2TRX5@28211|Alphaproteobacteria,43N7N@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158527_k127_4437848_2	261292.Nit79A3_3087	1.385e-22	103.0	COG5544@1|root,COG5544@2|Bacteria,1QU58@1224|Proteobacteria,2VQZ5@28216|Betaproteobacteria,3720M@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_4438164_1	443143.GM18_3660	1.016e-58	208.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria	1224|Proteobacteria	I	Dehydratase	maoC	-	4.2.1.148,4.2.1.56	ko:K14449,ko:K18290	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R02491,R05076	RC00730,RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
SRR25158527_k127_4438164_0	479434.Sthe_1794	3.14e-172	547.0	COG1960@1|root,COG1960@2|Bacteria,2G815@200795|Chloroflexi,27Z4U@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158527_k127_4438164_2	1120985.AUMI01000011_gene476	3.811e-07	61.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H3RK@909932|Negativicutes	909932|Negativicutes	EGP	Transporter major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3,Sugar_tr
SRR25158527_k127_4451177_0	1123060.JONP01000004_gene705	1.403e-111	369.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,2JQ9I@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0656 Aldo keto reductases, related to diketogulonate reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158527_k127_4451177_1	247490.KSU1_B0345	5.645e-11	74.0	COG1807@1|root,COG1807@2|Bacteria,2IZ8J@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 39	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
SRR25158527_k127_4454489_1	138119.DSY3752	3.786e-39	156.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	-	-	-	ko:K00183	-	-	-	-	ko00000	5.A.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SRR25158527_k127_4454489_3	331869.BAL199_19678	1.1e-36	145.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	decarboxylase	MA20_22785	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158527_k127_4454489_2	306281.AJLK01000056_gene4515	4.194e-37	144.0	2CCSR@1|root,32RWC@2|Bacteria,1G749@1117|Cyanobacteria,1JIYR@1189|Stigonemataceae	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
SRR25158527_k127_4454489_0	742821.HMPREF9464_00834	7.213e-187	599.0	COG1053@1|root,COG1053@2|Bacteria,1R0GR@1224|Proteobacteria,2WHU3@28216|Betaproteobacteria,4PRR9@995019|Sutterellaceae	28216|Betaproteobacteria	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
SRR25158527_k127_4458682_1	644966.Tmar_1759	8.186e-39	150.0	COG3427@1|root,COG3427@2|Bacteria,1VA2M@1239|Firmicutes,254US@186801|Clostridia	186801|Clostridia	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158527_k127_4458682_0	439235.Dalk_2812	2.672e-87	301.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2MHMR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158527_k127_4458682_3	1499967.BAYZ01000061_gene5953	3.766e-06	56.0	COG1475@1|root,COG1475@2|Bacteria,2NRF2@2323|unclassified Bacteria	2|Bacteria	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158527_k127_4458682_2	1499967.BAYZ01000061_gene5954	5.268e-20	93.0	COG1533@1|root,COG1533@2|Bacteria,2NPZ9@2323|unclassified Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
SRR25158527_k127_4460627_0	171693.BN988_00856	1.227e-73	258.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,23IY7@182709|Oceanobacillus	91061|Bacilli	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158527_k127_4460627_1	378806.STAUR_2293	7.733e-45	166.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2YYR9@29|Myxococcales	28221|Deltaproteobacteria	M	MltA specific insert domain	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
SRR25158527_k127_4462325_3	1038858.AXBA01000058_gene4337	8.544e-20	101.0	COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2U6AN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,NMT1_2
SRR25158527_k127_4462325_0	1187851.A33M_1060	1.134e-81	280.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,3FE0S@34008|Rhodovulum	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
SRR25158527_k127_4462325_1	1122915.AUGY01000118_gene6523	4.778e-44	170.0	COG0600@1|root,COG0600@2|Bacteria,1TQVZ@1239|Firmicutes,4I4D7@91061|Bacilli,272RG@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
SRR25158527_k127_4462325_2	1173024.KI912153_gene32	4.45e-20	93.0	COG0600@1|root,COG0600@2|Bacteria,1G0UB@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
SRR25158527_k127_4466268_1	1231391.AMZF01000046_gene961	2.329e-44	173.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_4466268_2	284031.JNXD01000025_gene367	1.65e-18	89.0	COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,Glyoxalase
SRR25158527_k127_4466268_0	710685.MycrhN_1853	8.904e-59	207.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria,23ACA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158527_k127_4466402_1	443152.MDG893_15295	5.057e-33	139.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_4466402_0	443152.MDG893_15295	1.028e-49	190.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_4466402_2	1173029.JH980292_gene2207	2.609e-09	59.0	COG3280@1|root,COG3280@2|Bacteria,1G3IR@1117|Cyanobacteria,1H9QJ@1150|Oscillatoriales	1117|Cyanobacteria	G	Maltooligosyl trehalose synthase	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158527_k127_4469144_1	891968.Anamo_1078	3.774e-19	89.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	4.1.1.55	ko:K04102	ko00624,ko01100,ko01120,map00624,map01100,map01120	M00623	R01635,R05375	RC00390	ko00000,ko00001,ko00002,ko01000	-	-	-	NMT1
SRR25158527_k127_4469144_2	1123376.AUIU01000019_gene1288	6.773e-05	51.0	28U9C@1|root,2ZGEW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_4469144_0	392499.Swit_0904	7.812e-125	411.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,2K6JZ@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182,ko:K16874	ko00130,ko00365,ko01100,ko01110,ko01120,map00130,map00365,map01100,map01110,map01120	M00117	R04985,R04986,R10213	RC00391,RC03086	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_447048_1	1396418.BATQ01000137_gene3897	6.076e-46	171.0	COG1595@1|root,COG1595@2|Bacteria,46WAZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158527_k127_447048_3	671143.DAMO_1470	3.267e-17	90.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
SRR25158527_k127_447048_0	1382359.JIAL01000001_gene2114	7.101e-47	179.0	COG0682@1|root,COG0682@2|Bacteria,3Y4QQ@57723|Acidobacteria,2JJ7E@204432|Acidobacteriia	204432|Acidobacteriia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SRR25158527_k127_447048_2	247490.KSU1_B0269	3.122e-31	132.0	COG3794@1|root,COG3794@2|Bacteria,2J06V@203682|Planctomycetes	203682|Planctomycetes	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3_3
SRR25158527_k127_447048_4	1033730.CAHG01000008_gene3197	5.485e-10	61.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4DQZC@85009|Propionibacteriales	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SRR25158527_k127_4478976_0	886293.Sinac_4912	5.283e-137	444.0	COG1533@1|root,COG1533@2|Bacteria,2IX0U@203682|Planctomycetes	203682|Planctomycetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158527_k127_4478976_1	365046.Rta_16040	3.129e-10	65.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,2WEEB@28216|Betaproteobacteria,4ADS9@80864|Comamonadaceae	28216|Betaproteobacteria	M	NmrA-like family	wbiB	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158527_k127_4481631_0	706587.Desti_4015	2.38e-50	184.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,2MRQA@213462|Syntrophobacterales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
SRR25158527_k127_4481631_1	1120956.JHZK01000011_gene1293	1.576e-26	112.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,1JPAN@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158527_k127_4481631_2	330214.NIDE2543	1.347e-06	53.0	COG0616@1|root,COG0616@2|Bacteria,3J13W@40117|Nitrospirae	40117|Nitrospirae	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SRR25158527_k127_4488952_0	1192034.CAP_6251	6.342e-80	284.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,437UX@68525|delta/epsilon subdivisions,2X34D@28221|Deltaproteobacteria,2YU7H@29|Myxococcales	1224|Proteobacteria	S	Amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_4488952_3	481448.Minf_1931	5.712e-16	83.0	COG2259@1|root,COG2259@2|Bacteria,46T2M@74201|Verrucomicrobia,37HAB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
SRR25158527_k127_4488952_1	224324.aq_2197	2.587e-46	171.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158527_k127_4488952_2	330214.NIDE3580	2.655e-18	84.0	COG1028@1|root,COG1028@2|Bacteria	330214.NIDE3580|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
SRR25158527_k127_4489145_1	1123360.thalar_02869	2.123e-62	216.0	29FX8@1|root,302UX@2|Bacteria,1RKA5@1224|Proteobacteria,2UH09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_4489145_0	748247.AZKH_4255	4.887e-151	489.0	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2VIF0@28216|Betaproteobacteria,2KXPU@206389|Rhodocyclales	206389|Rhodocyclales	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158527_k127_4497472_1	1453498.LG45_05585	2.401e-18	90.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,1HXWF@117743|Flavobacteriia,2NSSW@237|Flavobacterium	976|Bacteroidetes	EGP	MFS transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158527_k127_4497472_0	948106.AWZT01000001_gene5077	2.623e-177	570.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2WBWM@28216|Betaproteobacteria,1K6TM@119060|Burkholderiaceae	28216|Betaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_449761_1	644966.Tmar_1492	7.14e-64	229.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158527_k127_449761_0	1463857.JOFZ01000001_gene5444	3.719e-154	498.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158527_k127_4497833_0	1382304.JNIL01000001_gene2406	4.447e-77	276.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli	91061|Bacilli	EH	Acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158527_k127_4497833_1	1007105.PT7_0093	4.982e-07	60.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,3T1MD@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_4498430_0	686340.Metal_2995	9.163e-105	352.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,1RMCR@1236|Gammaproteobacteria,1XDRN@135618|Methylococcales	135618|Methylococcales	P	PFAM NnrS	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
SRR25158527_k127_4498430_1	1173263.Syn7502_03004	7.76e-07	55.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_450873_0	1184609.KILIM_110_00080	4.014e-45	177.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4F82D@85018|Dermatophilaceae	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158527_k127_450873_1	1122915.AUGY01000020_gene6479	1.302e-24	116.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_455159_0	547144.HydHO_1416	5.017e-208	656.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,2G4N5@200783|Aquificae	200783|Aquificae	CI	RnfC Barrel sandwich hybrid domain	-	-	6.4.1.7	ko:K20140	-	-	-	-	ko00000,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
SRR25158527_k127_455159_1	290397.Adeh_3929	7.334e-120	392.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158527_k127_455159_2	472759.Nhal_0042	4.535e-14	74.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1WX9W@135613|Chromatiales	135613|Chromatiales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SRR25158527_k127_458498_1	330084.JNYZ01000020_gene4708	1.313e-42	168.0	COG1506@1|root,COG1506@2|Bacteria,2I2J3@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Peptidase_S9
SRR25158527_k127_458498_0	663610.JQKO01000015_gene1906	8.405e-52	208.0	COG0642@1|root,COG2972@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria,3N9SQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
SRR25158527_k127_459162_2	1230476.C207_06807	1.835e-08	55.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2TRVA@28211|Alphaproteobacteria,3JZ7D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
SRR25158527_k127_459162_0	1054213.HMPREF9946_02833	5.259e-85	300.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2U0KX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG0402 Cytosine deaminase and related metal-dependent hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158527_k127_459162_1	1205680.CAKO01000004_gene3614	1.567e-15	79.0	COG5424@1|root,COG5424@2|Bacteria,1PVPF@1224|Proteobacteria,2U38I@28211|Alphaproteobacteria,2JYA4@204441|Rhodospirillales	204441|Rhodospirillales	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
SRR25158527_k127_461208_2	671143.DAMO_2633	1.438e-06	50.0	COG1253@1|root,COG1253@2|Bacteria,2NP04@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	ytfL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699,ko:K06189	-	-	-	-	ko00000,ko02000,ko02042	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21,TerC
SRR25158527_k127_461208_1	323261.Noc_0566	6.837e-37	143.0	COG0346@1|root,COG0346@2|Bacteria,1PT56@1224|Proteobacteria,1TAT2@1236|Gammaproteobacteria,1X1I3@135613|Chromatiales	135613|Chromatiales	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_461208_0	237368.SCABRO_00778	1.461e-105	353.0	COG0079@1|root,COG0079@2|Bacteria,2IWYA@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158527_k127_461673_2	521460.Athe_0320	1.334e-14	76.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,42EYZ@68295|Thermoanaerobacterales	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158527_k127_461673_1	1125863.JAFN01000001_gene901	4.037e-42	159.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
SRR25158527_k127_461673_0	1232410.KI421421_gene3588	3.642e-137	451.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SRR25158527_k127_461673_3	880072.Desac_2097	1.103e-12	68.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,2MQ7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158527_k127_46497_0	1125863.JAFN01000001_gene3452	4.093e-175	559.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
SRR25158527_k127_46497_1	537972.ABQU01000032_gene1560	4.458e-09	65.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42TPK@68525|delta/epsilon subdivisions,2YQ07@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158527_k127_466613_1	247490.KSU1_C0323	1.492e-64	231.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
SRR25158527_k127_466613_0	404589.Anae109_2548	2.9e-105	369.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
SRR25158527_k127_466613_2	1321778.HMPREF1982_00797	8.59e-07	55.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,24AHX@186801|Clostridia	186801|Clostridia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158527_k127_47256_1	1231391.AMZF01000068_gene2179	2.825e-39	160.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_47256_0	269799.Gmet_3493	1.059e-160	512.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome c oxidase, subunit I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SRR25158527_k127_477833_1	398767.Glov_1947	9.209e-48	179.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,43BTG@68525|delta/epsilon subdivisions,2X74B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158527_k127_477833_0	525146.Ddes_0128	3.04e-62	220.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2M82V@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158527_k127_477833_2	304371.MCP_2581	2.769e-28	118.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,2NAXV@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SRR25158527_k127_480327_2	671143.DAMO_3054	1.474e-07	61.0	COG5621@1|root,COG5621@2|Bacteria,2NPFN@2323|unclassified Bacteria	2|Bacteria	S	Lipocalin-like domain	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SRR25158527_k127_480327_0	1469245.JFBG01000009_gene565	4.723e-67	237.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RQNH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese-like domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158527_k127_480327_1	765420.OSCT_2153	1.946e-08	62.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_488729_0	909663.KI867150_gene2493	1.557e-22	104.0	COG0250@1|root,COG0250@2|Bacteria,1Q2A0@1224|Proteobacteria,437WT@68525|delta/epsilon subdivisions,2X36G@28221|Deltaproteobacteria,2MSA8@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
SRR25158527_k127_488729_1	1254432.SCE1572_17150	2.738e-06	58.0	COG0642@1|root,COG2205@2|Bacteria	1254432.SCE1572_17150|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_489566_2	333138.LQ50_20145	8.305e-07	54.0	COG3181@1|root,COG3181@2|Bacteria,1U3ZT@1239|Firmicutes,4IJY9@91061|Bacilli,1ZIAT@1386|Bacillus	91061|Bacilli	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_489566_1	1123060.JONP01000008_gene4561	1.048e-09	70.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_489566_0	1380356.JNIK01000017_gene2825	3.245e-10	65.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158527_k127_489566_3	909663.KI867150_gene2417	0.0004488	47.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
SRR25158527_k127_491912_1	1232410.KI421418_gene2160	1.63e-81	282.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43RY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase A domain	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158527_k127_491912_0	105559.Nwat_1144	3.263e-151	493.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
SRR25158527_k127_491912_2	608506.COB47_0651	0.0005948	42.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,247Q5@186801|Clostridia,42FAB@68295|Thermoanaerobacterales	186801|Clostridia	C	of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158527_k127_497146_2	156889.Mmc1_3502	2.857e-38	150.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SRR25158527_k127_497146_3	671143.DAMO_1589	1.635e-33	134.0	COG2332@1|root,COG2332@2|Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SRR25158527_k127_497146_0	671143.DAMO_1590	9.845e-73	252.0	COG0755@1|root,COG0755@2|Bacteria,2NPG8@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
SRR25158527_k127_497146_1	671143.DAMO_1591	1.385e-44	173.0	COG2386@1|root,COG2386@2|Bacteria,2NPSF@2323|unclassified Bacteria	2|Bacteria	O	CcmB protein	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193,ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	iECO111_1330.ECO111_2936,iYL1228.KPN_02080	CcmB
SRR25158527_k127_497146_4	1234364.AMSF01000080_gene3064	6.513e-05	47.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1T1HN@1236|Gammaproteobacteria,1X4CJ@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158527_k127_503242_0	105559.Nwat_0145	4.915e-139	447.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1WXWG@135613|Chromatiales	135613|Chromatiales	S	fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
SRR25158527_k127_503242_1	1487953.JMKF01000075_gene3748	2.968e-48	177.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158527_k127_503242_2	1162668.LFE_1237	2.071e-14	83.0	COG0412@1|root,COG0412@2|Bacteria,3J1B9@40117|Nitrospirae	40117|Nitrospirae	Q	Alpha/beta hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_503242_3	1205680.CAKO01000007_gene4355	3.69e-14	72.0	COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_507995_1	243365.CV_2289	2.475e-12	79.0	COG0715@1|root,COG0715@2|Bacteria,1PEQ8@1224|Proteobacteria,2W9A1@28216|Betaproteobacteria,2KT3B@206351|Neisseriales	206351|Neisseriales	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_507995_0	221288.JH992901_gene3895	6.602e-52	187.0	COG0715@1|root,COG0715@2|Bacteria,1GFIM@1117|Cyanobacteria	1117|Cyanobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
SRR25158527_k127_508063_1	399549.Msed_0664	4.406e-06	51.0	COG4034@1|root,arCOG04164@2157|Archaea,2XQFX@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF1152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1152
SRR25158527_k127_508063_0	1380394.JADL01000002_gene1439	3.212e-54	207.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VC6K@28211|Alphaproteobacteria,2JXZZ@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_508982_2	1120949.KB903314_gene304	3.083e-22	100.0	2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_508982_0	13689.BV96_04308	3.88e-96	325.0	COG0329@1|root,COG0329@2|Bacteria,1NTSZ@1224|Proteobacteria,2UNMN@28211|Alphaproteobacteria,2K8VP@204457|Sphingomonadales	204457|Sphingomonadales	EM	Dihydrodipicolinate synthetase family	-	-	4.1.2.45	ko:K14585	ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220	M00534	R05136	RC00924,RC00936	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_508982_1	243231.GSU2716	3.36e-79	271.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,42QXT@68525|delta/epsilon subdivisions,2WN0R@28221|Deltaproteobacteria,43T0X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sugar fermentation stimulation protein	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
SRR25158527_k127_51566_3	378806.STAUR_6411	1.173e-10	63.0	COG4942@1|root,COG4942@2|Bacteria	2|Bacteria	D	peptidase	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
SRR25158527_k127_51566_0	243231.GSU1772	3.005e-148	482.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,43TEQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SRR25158527_k127_51566_1	1232410.KI421421_gene3664	4.497e-122	405.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,43SB0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	OB-fold nucleic acid binding domain	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SRR25158527_k127_51566_2	644282.Deba_1930	1.497e-17	91.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2WP2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158527_k127_521346_1	1057002.KB905370_gene3454	2.241e-110	369.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,4B7FG@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SRR25158527_k127_521346_3	330214.NIDE3400	5.184e-96	323.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158527_k127_521346_2	330214.NIDE3399	1.342e-102	344.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	thuF	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02025,ko:K10237,ko:K15771	ko02010,map02010	M00204,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2	-	iNJ661.Rv1236	BPD_transp_1
SRR25158527_k127_521346_0	330214.NIDE3398	1.857e-124	411.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	thuE	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
SRR25158527_k127_522466_3	880072.Desac_1033	3.027e-15	81.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2X1XQ@28221|Deltaproteobacteria,2MRAF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158527_k127_522466_0	671143.DAMO_0005	5.528e-140	457.0	COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158527_k127_522466_1	1121396.KB892935_gene3861	2.225e-64	237.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,42PZA@68525|delta/epsilon subdivisions,2WJ9A@28221|Deltaproteobacteria,2MKHA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_522466_2	58344.JOEL01000022_gene962	8.378e-17	87.0	COG0043@1|root,COG0043@2|Bacteria,2GKSI@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the UbiD family	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_526205_2	96561.Dole_0908	2.229e-56	208.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,42Q00@68525|delta/epsilon subdivisions,2WJEM@28221|Deltaproteobacteria,2MIC2@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
SRR25158527_k127_526205_0	671143.DAMO_3115	1.045e-143	472.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degP	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SRR25158527_k127_526205_4	439235.Dalk_3378	5.633e-24	107.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SRR25158527_k127_526205_3	247490.KSU1_D0452	3.27e-35	149.0	COG0859@1|root,COG0859@2|Bacteria,2J4DC@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
SRR25158527_k127_526205_1	867903.ThesuDRAFT_01687	2.602e-75	259.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WCW0@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158527_k127_537428_1	56780.SYN_01525	5.127e-05	46.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MQS8@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158527_k127_537428_0	404589.Anae109_1327	5.511e-149	490.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,2YTVE@29|Myxococcales	28221|Deltaproteobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158527_k127_538920_0	479434.Sthe_1347	4.26e-65	231.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Y0Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158527_k127_542877_4	1121365.AQXB01000003_gene119	4.318e-10	65.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,22KAX@1653|Corynebacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA8	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158527_k127_542877_3	1463857.JOFZ01000001_gene5448	1.411e-16	91.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_542877_0	357804.Ping_1819	1.197e-150	489.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158527_k127_542877_2	1120949.KB903314_gene304	3.23e-81	286.0	2C1EV@1|root,33RW1@2|Bacteria,2ICZG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_542877_1	469383.Cwoe_4099	2.881e-83	288.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_545365_0	392499.Swit_0904	3.632e-130	429.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,2K6JZ@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182,ko:K16874	ko00130,ko00365,ko01100,ko01110,ko01120,map00130,map00365,map01100,map01110,map01120	M00117	R04985,R04986,R10213	RC00391,RC03086	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_545365_1	649638.Trad_0628	5.083e-14	83.0	COG0715@1|root,COG0715@2|Bacteria,1WJPE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_545365_2	1040989.AWZU01000105_gene133	1.981e-08	60.0	COG0457@1|root,COG0457@2|Bacteria,1N6TJ@1224|Proteobacteria,2UG5W@28211|Alphaproteobacteria,3JZ4G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
SRR25158527_k127_54753_1	639030.JHVA01000001_gene3926	2.716e-55	201.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_54753_2	1340493.JNIF01000003_gene1919	1.27e-38	162.0	COG5000@1|root,COG5000@2|Bacteria,3Y32Z@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158527_k127_54753_0	665952.HMPREF1015_00885	2.629e-101	340.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,1ZCD4@1386|Bacillus	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SRR25158527_k127_55188_1	225117.XP_009370404.1	5.405e-10	62.0	COG1877@1|root,KOG1050@2759|Eukaryota,37T7Y@33090|Viridiplantae,3GAHZ@35493|Streptophyta,4JKRB@91835|fabids	35493|Streptophyta	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158527_k127_55188_0	644282.Deba_0199	2.039e-165	531.0	COG1215@1|root,COG1215@2|Bacteria,1QVA1@1224|Proteobacteria,43BP8@68525|delta/epsilon subdivisions,2X70I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR25158527_k127_55188_2	797302.Halru_0839	3.164e-05	55.0	COG0475@1|root,COG0589@1|root,arCOG00449@2157|Archaea,arCOG01953@2157|Archaea,2XV77@28890|Euryarchaeota,23U1Z@183963|Halobacteria	183963|Halobacteria	P	COG0475 Kef-type K transport systems, membrane components	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SRR25158527_k127_5520_2	478741.JAFS01000001_gene1393	8.018e-45	165.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia,37GJA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158527_k127_5520_0	391625.PPSIR1_24779	3.101e-58	211.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158527_k127_5520_1	517418.Ctha_0772	2.795e-48	179.0	COG2839@1|root,COG2839@2|Bacteria,1FE53@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
SRR25158527_k127_562498_1	335283.Neut_0487	3.903e-77	263.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,372CA@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158527_k127_562498_0	1380386.JIAW01000010_gene4303	6.316e-105	357.0	COG2224@1|root,COG2224@2|Bacteria,2I926@201174|Actinobacteria,232A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Isocitrate lyase	aceAb	GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158527_k127_567831_5	1111069.TCCBUS3UF1_18960	2.983e-08	58.0	COG2366@1|root,COG2366@2|Bacteria,1WJ3J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	peptidase S45, penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158527_k127_567831_4	317936.Nos7107_5299	1.405e-25	114.0	COG0625@1|root,COG0625@2|Bacteria,1G4XE@1117|Cyanobacteria,1HJ9S@1161|Nostocales	1117|Cyanobacteria	O	PFAM Glutathione S-transferase, N-terminal	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
SRR25158527_k127_567831_3	339860.Msp_0278	1.062e-26	116.0	COG4032@1|root,arCOG01613@2157|Archaea,2XYBY@28890|Euryarchaeota,23PJE@183925|Methanobacteria	183925|Methanobacteria	S	sulfopyruvate decarboxylase, alpha subunit	comD	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158527_k127_567831_1	196490.AUEZ01000005_gene3542	2.077e-35	142.0	COG0028@1|root,COG0028@2|Bacteria,1R610@1224|Proteobacteria,2U43S@28211|Alphaproteobacteria,3JTBV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
SRR25158527_k127_567831_0	797210.Halxa_3361	1.343e-46	181.0	COG2141@1|root,arCOG02410@2157|Archaea,2XU72@28890|Euryarchaeota,23S3D@183963|Halobacteria	183963|Halobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_567831_2	485913.Krac_2132	3.161e-28	119.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	abmE	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158527_k127_568850_2	391937.NA2_14782	1.466e-10	67.0	COG0346@1|root,COG0346@2|Bacteria,1N491@1224|Proteobacteria,2UK4T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_4
SRR25158527_k127_568850_0	1105367.CG50_05270	6.408e-66	228.0	COG1853@1|root,COG1853@2|Bacteria,1Q6RV@1224|Proteobacteria,2US3U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158527_k127_568850_1	903818.KI912269_gene527	3.078e-38	149.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	2.3.1.183,2.3.1.82	ko:K03823,ko:K18816	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	br01600,ko00000,ko00001,ko01000,ko01504	-	-	-	Acetyltransf_1,Methyltransf_25
SRR25158527_k127_570142_1	392499.Swit_2091	1.665e-23	102.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2U2SV@28211|Alphaproteobacteria,2K9WC@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158527_k127_570142_0	443144.GM21_1991	9.373e-74	260.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
SRR25158527_k127_571368_0	479434.Sthe_1091	1.042e-317	982.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158527_k127_571368_1	264732.Moth_1850	8.182e-10	64.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158527_k127_57520_1	426716.JOAJ01000001_gene844	2.181e-14	84.0	COG0715@1|root,COG0715@2|Bacteria,2HHNY@201174|Actinobacteria,4FZGF@85025|Nocardiaceae	201174|Actinobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_57520_0	768706.Desor_1551	1.734e-70	256.0	28HF7@1|root,2ZAT5@2|Bacteria,1VT0D@1239|Firmicutes,24XG8@186801|Clostridia	186801|Clostridia	C	PFAM Glycine sarcosine betaine reductase component B subunits	-	-	-	-	-	-	-	-	-	-	-	-	Gly_reductase
SRR25158527_k127_576645_2	644282.Deba_3173	2.864e-26	108.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158527_k127_576645_0	335543.Sfum_1220	6.259e-146	485.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2MR17@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
SRR25158527_k127_576645_1	1121428.DESHY_10128___1	6.984e-70	243.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158527_k127_576836_2	1500257.JQNM01000014_gene2912	3.908e-134	434.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,4BCDD@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_576836_4	59374.Fisuc_1084	7.57e-16	89.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_576836_3	1231391.AMZF01000029_gene212	3.764e-51	189.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VKYY@28216|Betaproteobacteria,3T2CN@506|Alcaligenaceae	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SRR25158527_k127_576836_0	767817.Desgi_1433	3.497e-190	610.0	COG0365@1|root,COG0365@2|Bacteria,1UMN9@1239|Firmicutes,25GME@186801|Clostridia	186801|Clostridia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_576836_1	42256.RradSPS_1677	2.137e-170	549.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CRW6@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158527_k127_576836_6	5061.CADANGAP00003549	4.705e-08	55.0	2D5VX@1|root,2SZVZ@2759|Eukaryota,3AUCN@33154|Opisthokonta,3PI2S@4751|Fungi,3R5CR@4890|Ascomycota,20JN7@147545|Eurotiomycetes,3S65R@5042|Eurotiales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_576836_5	382464.ABSI01000012_gene2111	8.89e-09	58.0	COG2010@1|root,COG2010@2|Bacteria,46W25@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
SRR25158527_k127_576979_1	1144310.PMI07_004507	2.751e-18	96.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,4B98I@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_576979_0	1056816.JAFQ01000004_gene5659	6.439e-26	111.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4G3XZ@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_582608_1	1038859.AXAU01000027_gene2240	4.115e-12	67.0	COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2TUUS@28211|Alphaproteobacteria,3JUFJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Cupin domain	-	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2
SRR25158527_k127_582608_0	234267.Acid_6640	1.629e-141	466.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,3Y2V9@57723|Acidobacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K02584,ko:K07713,ko:K15836,ko:K21009	ko02020,ko02025,map02020,map02025	M00499	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	GAF,GAF_2,HTH_8,PocR,Sigma54_activat,Yop-YscD_cpl
SRR25158527_k127_583725_2	1459636.NTE_00100	3.205e-43	160.0	COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SRR25158527_k127_583725_1	309801.trd_A0007	1.459e-57	206.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,27Y9H@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158527_k127_583725_0	1382356.JQMP01000001_gene1157	1.253e-171	548.0	COG1060@1|root,COG1060@2|Bacteria,2GBD4@200795|Chloroflexi,27YV4@189775|Thermomicrobia	189775|Thermomicrobia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158527_k127_585536_1	909663.KI867150_gene877	7.629e-58	206.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43D5Y@68525|delta/epsilon subdivisions,2X8CR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158527_k127_585536_2	909663.KI867150_gene876	1.588e-18	96.0	COG1196@1|root,COG1196@2|Bacteria,1NQEI@1224|Proteobacteria,42XZI@68525|delta/epsilon subdivisions,2WTDN@28221|Deltaproteobacteria,2MSDB@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_585536_0	909663.KI867150_gene875	1.545e-190	606.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR1E@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07714,ko:K07715	ko02020,ko02024,map02020,map02024	M00500,M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_595609_2	671143.DAMO_0699	4.127e-32	126.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
SRR25158527_k127_595609_1	706587.Desti_0523	1.954e-141	464.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2MQ4P@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SRR25158527_k127_595609_0	370438.PTH_1585	6.832e-188	609.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,2610T@186807|Peptococcaceae	186801|Clostridia	G	PFAM glycoside hydrolase family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158527_k127_595609_3	1379698.RBG1_1C00001G0089	9.705e-06	49.0	COG0709@1|root,COG0709@2|Bacteria,2NNUD@2323|unclassified Bacteria	2|Bacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
SRR25158527_k127_596112_1	481448.Minf_0575	1.059e-23	106.0	COG2105@1|root,COG2105@2|Bacteria	2|Bacteria	F	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2,GGACT,Gamma_PGA_hydro
SRR25158527_k127_596112_0	76114.ebA6298	1.958e-85	303.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,2KV0V@206389|Rhodocyclales	206389|Rhodocyclales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
SRR25158527_k127_599900_1	338963.Pcar_1971	3.323e-63	226.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43S1Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	HK	HTH domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158527_k127_599900_0	1278073.MYSTI_03801	4.054e-103	341.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2YTUR@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
SRR25158527_k127_599900_2	880072.Desac_2391	2.632e-49	181.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158527_k127_600871_0	95619.PM1_0203925	4.869e-47	175.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,1RQD0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158527_k127_600871_1	1206733.BAGC01000009_gene5110	1.602e-25	120.0	COG0329@1|root,COG0329@2|Bacteria,2GXMT@201174|Actinobacteria,4FYSW@85025|Nocardiaceae	201174|Actinobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA3	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_603547_1	398767.Glov_2936	8.231e-35	140.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,43UT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158527_k127_603547_0	443143.GM18_4206	5.76e-187	597.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,43T5X@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
SRR25158527_k127_605083_0	1500257.JQNM01000014_gene2912	1.929e-69	246.0	COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,4BCDD@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	4,5-dihydroxyphthalate decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_605083_1	1394178.AWOO02000003_gene2625	7.673e-55	205.0	COG2141@1|root,COG2141@2|Bacteria,2HF69@201174|Actinobacteria,4ENCI@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_605238_0	1123501.KB902290_gene1571	1.386e-148	493.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158527_k127_605238_1	1082931.KKY_2644	6.076e-40	162.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TRAP transporter solute receptor TAXI family protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158527_k127_606189_0	765420.OSCT_2032	8.184e-172	553.0	COG3280@1|root,COG3280@2|Bacteria	2|Bacteria	G	synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
SRR25158527_k127_609177_1	1454004.AW11_02632	6.244e-109	362.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VMKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158527_k127_609177_0	338966.Ppro_0408	2.004e-111	370.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_614652_0	1142394.PSMK_08370	4.406e-84	290.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158527_k127_614652_1	795359.TOPB45_0428	3.818e-52	194.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,2GH8K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
SRR25158527_k127_618488_1	1265310.CCBD010000061_gene1162	9.686e-34	142.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_618488_0	710686.Mycsm_03169	5.845e-54	203.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_619376_3	1280688.AUJB01000008_gene1237	0.0004736	42.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3NHRR@46205|Pseudobutyrivibrio	186801|Clostridia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SRR25158527_k127_619376_1	316067.Geob_0689	1.134e-128	424.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
SRR25158527_k127_619376_0	1125863.JAFN01000001_gene1723	2.021e-161	518.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158527_k127_619376_2	264732.Moth_2396	5.507e-61	221.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,42F18@68295|Thermoanaerobacterales	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SRR25158527_k127_620108_0	1110502.TMO_0012	6.687e-46	179.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM amidohydrolase	MA20_19310	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_620108_1	42256.RradSPS_1881	4.934e-05	48.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CPC0@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158527_k127_62630_0	290397.Adeh_4214	8.385e-265	827.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2YUCV@29|Myxococcales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
SRR25158527_k127_627217_0	264198.Reut_C6311	2.572e-108	364.0	COG0715@1|root,COG0715@2|Bacteria,1NS24@1224|Proteobacteria	1224|Proteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
SRR25158527_k127_627217_4	744872.Spica_0618	6.09e-20	95.0	COG1917@1|root,COG1917@2|Bacteria,2JAJW@203691|Spirochaetes	203691|Spirochaetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_627217_3	224914.BMEI0273	8.005e-33	135.0	COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria,1J2XA@118882|Brucellaceae	28211|Alphaproteobacteria	S	Haem-degrading	MA20_43165	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
SRR25158527_k127_627217_1	671143.DAMO_1713	1.406e-52	192.0	COG1678@1|root,COG1678@2|Bacteria	2|Bacteria	K	ribonucleoside-diphosphate reductase activity	MA20_18155	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SRR25158527_k127_627217_2	479432.Sros_8570	2.137e-39	152.0	COG5015@1|root,COG5015@2|Bacteria,2I3I5@201174|Actinobacteria,4EJIN@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158527_k127_62767_1	1500257.JQNM01000014_gene2939	5.958e-19	95.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,2UI7P@28211|Alphaproteobacteria,4BMG3@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_62767_0	1231391.AMZF01000019_gene2027	3.619e-58	211.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
SRR25158527_k127_628050_1	1504981.KO116_3413	0.0002404	51.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1XHVN@135619|Oceanospirillales	135619|Oceanospirillales	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_628050_0	935840.JAEQ01000004_gene643	7.771e-52	198.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
SRR25158527_k127_633080_2	1125863.JAFN01000001_gene3041	2.931e-09	65.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,FecR,LysM,Peptidase_M15_2,Peptidase_M74
SRR25158527_k127_633080_0	243231.GSU3365	1.079e-163	527.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43TS3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158527_k127_633080_1	1097668.BYI23_C003130	1.178e-107	364.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2WBWM@28216|Betaproteobacteria,1K6TM@119060|Burkholderiaceae	28216|Betaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
SRR25158527_k127_635236_1	1307759.JOMJ01000003_gene890	1.018e-28	133.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2M89I@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SRR25158527_k127_635236_2	338966.Ppro_1919	7.856e-14	83.0	COG0845@1|root,COG0845@2|Bacteria,1MV1R@1224|Proteobacteria,42PEF@68525|delta/epsilon subdivisions,2WJ93@28221|Deltaproteobacteria,43T3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SRR25158527_k127_635236_0	1121439.dsat_2813	4.31e-170	550.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SRR25158527_k127_638067_1	224911.27351915	4.987e-44	169.0	COG1028@1|root,COG1028@2|Bacteria,1R8EI@1224|Proteobacteria,2U2NQ@28211|Alphaproteobacteria,3JTNH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
SRR25158527_k127_638067_0	1382356.JQMP01000004_gene583	2.126e-268	838.0	COG0365@1|root,COG0365@2|Bacteria,2G5KE@200795|Chloroflexi,27XEK@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158527_k127_6440_2	111780.Sta7437_2730	1.706e-16	89.0	COG0457@1|root,COG0457@2|Bacteria,1G3MN@1117|Cyanobacteria,3VKXC@52604|Pleurocapsales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
SRR25158527_k127_6440_0	2074.JNYD01000038_gene523	3.441e-23	111.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DXC0@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_645217_2	485913.Krac_0364	6.988e-19	93.0	COG0043@1|root,COG0043@2|Bacteria,2G8WC@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_645217_0	1123504.JQKD01000049_gene2989	3.346e-63	232.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VRUP@28216|Betaproteobacteria,4AJ7Z@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
SRR25158527_k127_645217_1	1236973.JCM9157_769	6.475e-33	139.0	COG0329@1|root,COG0329@2|Bacteria,1V10S@1239|Firmicutes,4HGKS@91061|Bacilli,1ZEYH@1386|Bacillus	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	4.1.2.28,4.3.3.7	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01782,R10147	RC00307,RC00572,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158527_k127_645217_3	1220534.B655_0036	4.509e-13	76.0	COG4032@1|root,arCOG01613@2157|Archaea,2XYBY@28890|Euryarchaeota,23PJE@183925|Methanobacteria	183925|Methanobacteria	S	sulfopyruvate decarboxylase, alpha subunit	comD	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
SRR25158527_k127_651614_2	1123242.JH636438_gene5714	1.771e-27	113.0	COG4276@1|root,COG4276@2|Bacteria,2J0FI@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SRR25158527_k127_651614_0	330214.NIDE0204	8.691e-112	371.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,3J13F@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
SRR25158527_k127_651614_1	867903.ThesuDRAFT_01424	2.262e-91	310.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia	186801|Clostridia	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SRR25158527_k127_651614_3	946483.Cenrod_2569	8.135e-24	111.0	COG5012@1|root,COG5012@2|Bacteria,1PK4R@1224|Proteobacteria,2VTYG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158527_k127_651716_1	85681.XP_006450644.1	7.281e-70	244.0	COG0115@1|root,KOG0975@2759|Eukaryota,37N35@33090|Viridiplantae,3G9PH@35493|Streptophyta	35493|Streptophyta	E	Branched-chain-amino-acid aminotransferase-like protein 3	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046482,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.3.38	ko:K18482	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR25158527_k127_651716_2	264462.Bd1389	4.025e-61	217.0	COG3148@1|root,COG3148@2|Bacteria,1QJR0@1224|Proteobacteria,42UN7@68525|delta/epsilon subdivisions,2MUDY@213481|Bdellovibrionales,2WQDN@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
SRR25158527_k127_651716_0	1122915.AUGY01000118_gene6532	5.93e-106	356.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02575,ko:K08223	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.35,2.A.1.8	-	-	MFS_1
SRR25158527_k127_654696_1	666685.R2APBS1_0371	3.906e-07	55.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales	135614|Xanthomonadales	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158527_k127_654696_0	240015.ACP_0733	7.728e-194	618.0	COG2759@1|root,COG2759@2|Bacteria,3Y338@57723|Acidobacteria,2JMF8@204432|Acidobacteriia	204432|Acidobacteriia	H	Formate--tetrahydrofolate ligase	-	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158527_k127_654843_0	222534.KB893673_gene231	5.796e-24	107.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158527_k127_654843_1	1192868.CAIU01000020_gene2935	3.819e-09	68.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2V7D9@28211|Alphaproteobacteria,43KPE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
SRR25158527_k127_656266_0	1125863.JAFN01000001_gene3452	2.39e-75	271.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
SRR25158527_k127_656266_1	525897.Dbac_2683	3.245e-24	108.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2MBT4@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158527_k127_658383_0	1547437.LL06_05475	8.067e-23	104.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,2TSQU@28211|Alphaproteobacteria,43H33@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SRR25158527_k127_658383_1	1532558.JL39_06940	1.709e-20	104.0	COG1840@1|root,COG1840@2|Bacteria,1PGNJ@1224|Proteobacteria,2V7JA@28211|Alphaproteobacteria,4BDDZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
SRR25158527_k127_658427_0	330214.NIDE3865	1.327e-126	415.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SRR25158527_k127_664695_0	215803.DB30_4494	1.03e-89	308.0	COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,433V8@68525|delta/epsilon subdivisions,2X3MJ@28221|Deltaproteobacteria,2YWID@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SRR25158527_k127_664695_2	1297742.A176_00532	8.738e-22	109.0	COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria	1224|Proteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158527_k127_664695_1	751944.HALDL1_10460	4.238e-45	175.0	COG2141@1|root,arCOG02410@2157|Archaea,2XU72@28890|Euryarchaeota,23S3D@183963|Halobacteria	183963|Halobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	mer2	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_666618_1	627192.SLG_12110	0.0007466	49.0	COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,2U0GU@28211|Alphaproteobacteria,2K459@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158527_k127_666618_0	1122917.KB899674_gene312	3.055e-55	203.0	COG1335@1|root,COG1335@2|Bacteria,1VA32@1239|Firmicutes,4HKVT@91061|Bacilli,26XP2@186822|Paenibacillaceae	91061|Bacilli	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
SRR25158527_k127_667967_0	329726.AM1_0903	4.592e-126	409.0	COG2040@1|root,COG2040@2|Bacteria,1G1ZI@1117|Cyanobacteria	1117|Cyanobacteria	H	Homocysteine s-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
SRR25158527_k127_667967_1	1123487.KB892849_gene269	4.28e-50	183.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2VSWJ@28216|Betaproteobacteria,2KWKH@206389|Rhodocyclales	206389|Rhodocyclales	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_7,Acetyltransf_9
SRR25158527_k127_671535_0	218284.CCDN010000001_gene1804	1.97e-108	374.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,1ZCMT@1386|Bacillus	91061|Bacilli	S	Penicillin amidase	acyII	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158527_k127_678400_0	671143.DAMO_1165	1.154e-114	378.0	COG0843@1|root,COG0843@2|Bacteria,2NNTQ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxN	GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158527_k127_678400_1	671143.DAMO_1166	1.344e-73	253.0	COG1622@1|root,COG1622@2|Bacteria,2NNSH@2323|unclassified Bacteria	2|Bacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxM	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SRR25158527_k127_678400_3	1120705.FG95_01772	0.000357	50.0	COG1276@1|root,COG1276@2|Bacteria,1RDPK@1224|Proteobacteria,2VEVW@28211|Alphaproteobacteria,2KDU8@204457|Sphingomonadales	204457|Sphingomonadales	P	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
SRR25158527_k127_678400_2	1298867.AUES01000014_gene4322	2.493e-06	59.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,3JTHB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158527_k127_682605_0	1121405.dsmv_1861	1.357e-316	987.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MIS4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,PTS_EIIA_2
SRR25158527_k127_686566_0	861299.J421_3613	2.42e-303	944.0	COG3808@1|root,COG3808@2|Bacteria,1ZT09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158527_k127_686566_1	1448857.JFAP01000007_gene271	2.49e-52	192.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2YM87@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158527_k127_691491_0	379066.GAU_0748	4.832e-81	284.0	COG0508@1|root,COG0508@2|Bacteria,1ZSYJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158527_k127_691491_2	671143.DAMO_2791	1.096e-28	117.0	COG1193@1|root,COG1193@2|Bacteria,2NRN7@2323|unclassified Bacteria	2|Bacteria	L	Smr domain	mutS2	GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158527_k127_691491_1	1232410.KI421420_gene3159	4.214e-40	154.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158527_k127_692716_0	246196.MSMEI_2053	3.969e-31	138.0	COG0624@1|root,COG0624@2|Bacteria,2I9Y6@201174|Actinobacteria,23ER8@1762|Mycobacteriaceae	201174|Actinobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158527_k127_694103_0	671143.DAMO_1145	5.139e-58	213.0	COG3842@1|root,COG3842@2|Bacteria,2NNPE@2323|unclassified Bacteria	2|Bacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	gtsA	-	3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55	ko:K02010,ko:K02045,ko:K02049,ko:K02068,ko:K02071,ko:K06857,ko:K10112,ko:K11072	ko00920,ko02010,map00920,map02010	M00185,M00186,M00188,M00190,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00211,M00238,M00299,M00491,M00602,M00605,M00606	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.10,3.A.1.11.1,3.A.1.16,3.A.1.17,3.A.1.24,3.A.1.6.1,3.A.1.6.2,3.A.1.6.3,3.A.1.6.4	-	-	ABC_tran,TOBE_2
SRR25158527_k127_694103_2	1173028.ANKO01000117_gene5934	2.744e-23	102.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
SRR25158527_k127_694103_1	1366050.N234_20795	1.379e-57	215.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2VM18@28216|Betaproteobacteria,1KD4T@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Pfam:AmoA	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
SRR25158527_k127_694103_3	683837.lse_0770	5.347e-09	66.0	COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli,26JXH@186820|Listeriaceae	91061|Bacilli	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_695559_1	1118054.CAGW01000075_gene3261	1.756e-08	66.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_695559_0	717231.Flexsi_0625	3.94e-58	205.0	COG0075@1|root,COG0075@2|Bacteria,2GEIZ@200930|Deferribacteres	200930|Deferribacteres	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158527_k127_698247_2	1123072.AUDH01000002_gene2366	2.775e-43	163.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,2JPI5@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0765 ABC-type amino acid transport system, permease component	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158527_k127_698247_0	1121861.KB899912_gene973	3.067e-104	355.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,2JQ13@204441|Rhodospirillales	204441|Rhodospirillales	E	acid transport system permease	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
SRR25158527_k127_698247_1	1121861.KB899935_gene468	1.231e-93	310.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,2JQ3B@204441|Rhodospirillales	204441|Rhodospirillales	ET	general L-amino acid-binding periplasmic protein AapJ	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
SRR25158527_k127_70374_1	443152.MDG893_15085	8.184e-38	153.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_70374_0	1144310.PMI07_005447	1.579e-56	211.0	COG3181@1|root,COG3181@2|Bacteria,1N8DG@1224|Proteobacteria,2VFU9@28211|Alphaproteobacteria,4BNCX@82115|Rhizobiaceae	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_705908_0	561175.KB894098_gene5378	1.692e-22	106.0	COG2153@1|root,COG2153@2|Bacteria,2IFAM@201174|Actinobacteria,4EK08@85012|Streptosporangiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
SRR25158527_k127_705908_2	1144310.PMI07_006532	2.493e-05	53.0	COG0715@1|root,COG0715@2|Bacteria,1NS0V@1224|Proteobacteria,2UI8H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_706761_0	1382304.JNIL01000001_gene1506	7.43e-99	337.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,278QK@186823|Alicyclobacillaceae	91061|Bacilli	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158527_k127_706761_1	865861.AZSU01000001_gene549	1.518e-46	172.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,36IEF@31979|Clostridiaceae	186801|Clostridia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158527_k127_706761_2	867903.ThesuDRAFT_01356	6.811e-09	60.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158527_k127_7169_2	335543.Sfum_1226	0.0005913	44.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria,2MS47@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158527_k127_7169_0	316067.Geob_1719	4.172e-92	316.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
SRR25158527_k127_7169_1	338966.Ppro_3079	3.536e-40	158.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_717907_4	398527.Bphyt_2223	0.0009687	42.0	COG0346@1|root,COG0346@2|Bacteria,1PK3B@1224|Proteobacteria,2W8DQ@28216|Betaproteobacteria,1K798@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158527_k127_717907_0	926566.Terro_1977	3.46e-99	332.0	COG0761@1|root,COG0761@2|Bacteria,3Y40M@57723|Acidobacteria,2JIXC@204432|Acidobacteriia	204432|Acidobacteriia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158527_k127_717907_1	1232410.KI421412_gene406	1.633e-58	217.0	COG1193@1|root,COG1193@2|Bacteria,1QYV7@1224|Proteobacteria	1224|Proteobacteria	L	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_717907_2	1159870.KB907784_gene580	1.219e-13	72.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Cold shock protein	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158527_k127_717907_3	1382306.JNIM01000001_gene466	4.817e-12	65.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158527_k127_719581_0	398767.Glov_2680	4.248e-127	426.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158527_k127_719581_1	316067.Geob_3461	7.74e-73	256.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158527_k127_724809_0	1458275.AZ34_03355	3.704e-47	176.0	COG1073@1|root,COG1073@2|Bacteria,1PJHS@1224|Proteobacteria,2VXXE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100
SRR25158527_k127_724809_1	1071085.KK033114_gene736	6.263e-40	154.0	arCOG08934@1|root,arCOG08934@2157|Archaea,2XXBA@28890|Euryarchaeota	28890|Euryarchaeota	Q	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158527_k127_726395_0	195105.CN97_19055	8.721e-84	297.0	COG0747@1|root,COG0747@2|Bacteria,1MWGY@1224|Proteobacteria,2TR73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158527_k127_74202_4	926692.AZYG01000040_gene1540	1.637e-78	269.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
SRR25158527_k127_74202_0	1125863.JAFN01000001_gene910	8.084e-248	775.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
SRR25158527_k127_74202_2	398767.Glov_2172	3.395e-110	362.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
SRR25158527_k127_74202_1	338963.Pcar_1943	2.965e-115	380.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,43S6C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SIS domain	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
SRR25158527_k127_74202_5	269799.Gmet_1279	9.522e-51	185.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WPT4@28221|Deltaproteobacteria,43UYH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
SRR25158527_k127_74202_7	1121413.JMKT01000008_gene1448	3.632e-05	53.0	COG3117@1|root,COG3117@2|Bacteria	2|Bacteria	P	lipopolysaccharide transmembrane transporter activity	lptC	-	-	ko:K09774,ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
SRR25158527_k127_74202_6	648885.KB316283_gene3655	5.29e-15	82.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,1JRSJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM OstA family protein	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SRR25158527_k127_74202_3	1232410.KI421421_gene3587	6.575e-92	308.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,43T7P@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158527_k127_746743_0	443144.GM21_1940	7.336e-178	574.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158527_k127_749240_1	637905.SVI_1062	5.556e-63	224.0	COG3221@1|root,COG3221@2|Bacteria,1PFPM@1224|Proteobacteria,1SXBG@1236|Gammaproteobacteria,2QDCZ@267890|Shewanellaceae	1236|Gammaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SRR25158527_k127_749240_2	472759.Nhal_2663	2.435e-40	154.0	COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,1SE87@1236|Gammaproteobacteria,1WZJ6@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158527_k127_749240_0	1395571.TMS3_0107090	5.484e-95	321.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	sumf2	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158527_k127_749317_0	545694.TREPR_2877	7.122e-105	345.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_749317_2	35754.JNYJ01000001_gene7243	4.677e-14	75.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,4DJZN@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_749317_1	479434.Sthe_2790	1.263e-34	143.0	COG0477@1|root,COG0477@2|Bacteria,2G5YG@200795|Chloroflexi,27XKV@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158527_k127_758134_2	251221.35212389	1.094e-05	48.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
SRR25158527_k127_758134_0	498848.TaqDRAFT_3770	5.616e-128	422.0	COG0683@1|root,COG0683@2|Bacteria,1WI02@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158527_k127_758134_1	1009370.ALO_16377	1.998e-87	295.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H1WX@909932|Negativicutes	909932|Negativicutes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158527_k127_772237_0	1125863.JAFN01000001_gene1090	4.161e-95	325.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
SRR25158527_k127_772237_4	1234664.AMRO01000035_gene2707	1.781e-05	51.0	COG0662@1|root,COG0662@2|Bacteria,1VE4V@1239|Firmicutes	1239|Firmicutes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_772237_2	284031.JNXD01000025_gene367	3.634e-26	112.0	COG0346@1|root,COG4319@1|root,COG0346@2|Bacteria,COG4319@2|Bacteria,2IIN9@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,Glyoxalase
SRR25158527_k127_772237_3	1132836.RCCGE510_04897	4.799e-13	80.0	COG0715@1|root,COG0715@2|Bacteria,1Q6YX@1224|Proteobacteria,2U4A5@28211|Alphaproteobacteria,4BBDJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
SRR25158527_k127_772237_1	1121106.JQKB01000002_gene3468	1.11e-56	208.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JQSB@204441|Rhodospirillales	204441|Rhodospirillales	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
SRR25158527_k127_778004_0	1379698.RBG1_1C00001G1237	8.794e-54	194.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	zraR	GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SRR25158527_k127_778004_1	525897.Dbac_1016	1.201e-45	179.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MASE1,PAS,PAS_4,PAS_9,Response_reg
SRR25158527_k127_779184_0	66429.JOFL01000028_gene5062	4.21e-80	278.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_780996_1	562970.Btus_0974	1.548e-11	65.0	COG1853@1|root,COG1853@2|Bacteria,1V7DF@1239|Firmicutes,4HISF@91061|Bacilli,279Y6@186823|Alicyclobacillaceae	91061|Bacilli	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158527_k127_780996_0	1132509.C447_11805	1.662e-24	115.0	arCOG08113@1|root,arCOG08113@2157|Archaea,2XWRR@28890|Euryarchaeota,23V69@183963|Halobacteria	183963|Halobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_783397_4	1304880.JAGB01000002_gene1994	2.023e-11	65.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase
SRR25158527_k127_783397_1	324057.Pjdr2_5708	4.205e-49	185.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,26QP8@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
SRR25158527_k127_783397_0	1278073.MYSTI_03019	3.317e-54	195.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2YVAI@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, CarD family	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158527_k127_783397_3	404589.Anae109_2472	2.831e-30	126.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158527_k127_783397_2	391625.PPSIR1_08911	9.532e-36	152.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2X3DV@28221|Deltaproteobacteria,2YVMF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
SRR25158527_k127_788125_3	1408422.JHYF01000001_gene2894	8.782e-05	48.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,36FQG@31979|Clostridiaceae	186801|Clostridia	M	PFAM NLP P60 protein	-	-	3.5.1.28	ko:K01447,ko:K11060,ko:K21471	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011,ko02042	-	-	-	NLPC_P60,SH3_3
SRR25158527_k127_788125_0	1173021.ALWA01000037_gene3499	2.349e-35	151.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158527_k127_788125_1	1122915.AUGY01000118_gene6536	5.895e-12	76.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,26UBJ@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_788125_2	690585.JNNU01000008_gene3736	5.899e-05	51.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2TTD4@28211|Alphaproteobacteria,4B98I@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_796068_0	1121448.DGI_3412	5.787e-101	333.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2M9TD@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158527_k127_796068_1	706587.Desti_3975	6.325e-61	216.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2MRJU@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158527_k127_796068_2	203275.BFO_1444	8.17e-14	73.0	COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,2FMM4@200643|Bacteroidia,22WWT@171551|Porphyromonadaceae	976|Bacteroidetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158527_k127_798820_1	316274.Haur_4687	7.541e-108	358.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi,374UE@32061|Chloroflexia	32061|Chloroflexia	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SRR25158527_k127_798820_4	706587.Desti_2225	3.43e-40	154.0	COG3787@1|root,COG3787@2|Bacteria,1N6XR@1224|Proteobacteria,42VZH@68525|delta/epsilon subdivisions,2WRXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158527_k127_798820_5	1038869.AXAN01000003_gene2653	9.338e-16	85.0	2DAI9@1|root,32TVI@2|Bacteria,1R3N0@1224|Proteobacteria,2WIIK@28216|Betaproteobacteria,1K90U@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158527_k127_798820_2	443143.GM18_2043	5.652e-100	341.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SRR25158527_k127_798820_3	1382306.JNIM01000001_gene783	2.83e-90	304.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158527_k127_798820_0	398767.Glov_3570	1.77e-133	436.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158527_k127_79897_1	208444.JNYY01000019_gene197	7.562e-06	48.0	COG0834@1|root,COG0834@2|Bacteria,2HWVX@201174|Actinobacteria,4E8J7@85010|Pseudonocardiales	201174|Actinobacteria	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
SRR25158527_k127_79897_0	886293.Sinac_1683	1.591e-109	368.0	COG2271@1|root,COG2271@2|Bacteria,2IY09@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_80191_1	1121440.AUMA01000003_gene2827	6.662e-71	248.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MG8Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158527_k127_80191_0	1205680.CAKO01000002_gene2142	5.981e-71	246.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158527_k127_810777_1	1454004.AW11_00204	2.234e-85	293.0	COG3597@1|root,COG3597@2|Bacteria,1QG9J@1224|Proteobacteria,2VIRR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	DUF533,TerB
SRR25158527_k127_810777_0	330214.NIDE2929	3.249e-187	593.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	2|Bacteria	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	3.4.21.53	ko:K03798,ko:K04076,ko:K13525,ko:K17681	ko04141,ko05134,map04141,map05134	M00400,M00403,M00742	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03019,ko03029,ko03110,ko04131,ko04147	3.A.16.1	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158527_k127_811_0	266265.Bxe_C1059	3.424e-151	493.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,1K3N4@119060|Burkholderiaceae	28216|Betaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158527_k127_811462_2	243231.GSU1659	7.58e-20	90.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,43TYY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158527_k127_811462_1	1121289.JHVL01000062_gene263	3.562e-23	108.0	28PHB@1|root,2ZC7V@2|Bacteria,1V1MY@1239|Firmicutes,24H5K@186801|Clostridia,36IHD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_811462_0	1123504.JQKD01000049_gene2989	6.364e-62	231.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2VRUP@28216|Betaproteobacteria,4AJ7Z@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
SRR25158527_k127_815026_1	1499967.BAYZ01000152_gene1432	3.471e-66	233.0	COG1131@1|root,COG1131@2|Bacteria,2NPDQ@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	natA2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158527_k127_815026_0	706587.Desti_4625	1.91e-72	263.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SRR25158527_k127_815504_0	1304866.K413DRAFT_0205	1.694e-33	141.0	COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,25DGF@186801|Clostridia,36FGS@31979|Clostridiaceae	186801|Clostridia	M	mandelate racemase muconate lactonizing	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158527_k127_815504_1	1236959.BAMT01000005_gene51	2.502e-32	131.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,2W7ZA@28216|Betaproteobacteria,2KMVH@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_815504_2	338966.Ppro_2232	2.119e-13	72.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,43UG1@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	TIGRFAM phosphoenolpyruvate-protein phosphotransferase	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158527_k127_815867_1	1123501.KB902297_gene3631	2.847e-80	278.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158527_k127_815867_0	105422.BBPM01000113_gene3362	1.194e-136	454.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,2NKS5@228398|Streptacidiphilus	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1,SBP_bac_6
SRR25158527_k127_815867_2	105422.BBPM01000113_gene3361	3.28e-47	184.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158527_k127_81625_0	1047013.AQSP01000118_gene1232	3.731e-20	100.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K02051,ko:K03286	-	M00188	-	-	ko00000,ko00002,ko02000	1.B.6,3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,OmpA
SRR25158527_k127_81625_1	1120936.KB907209_gene1441	1.348e-09	69.0	COG0715@1|root,COG0715@2|Bacteria,2GK7X@201174|Actinobacteria,4EI7Q@85012|Streptosporangiales	201174|Actinobacteria	P	NMT1-like family	ssuA3	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_819110_2	861299.J421_0812	5.639e-33	139.0	COG0612@1|root,COG0612@2|Bacteria,1ZT6X@142182|Gemmatimonadetes	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158527_k127_819110_0	517418.Ctha_2620	7.636e-88	308.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158527_k127_819110_1	886293.Sinac_7123	1.144e-34	144.0	COG0412@1|root,COG0412@2|Bacteria,2IYMM@203682|Planctomycetes	203682|Planctomycetes	Q	COG0412 Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_824752_1	1082931.KKY_2644	1.247e-13	76.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TRAP transporter solute receptor TAXI family protein	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
SRR25158527_k127_824752_0	1123501.KB902290_gene1571	6.852e-174	566.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158527_k127_828787_0	760568.Desku_1070	3.497e-53	198.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,260R2@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
SRR25158527_k127_828787_1	1121405.dsmv_0325	1.35e-50	197.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2MHRK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
SRR25158527_k127_833056_1	551275.KB899544_gene1848	4.829e-12	69.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,43WG0@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158527_k127_833056_0	1123247.AUIJ01000036_gene1398	4.319e-32	137.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2VF6Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158527_k127_833056_2	1230342.CTM_13528	2.264e-08	66.0	COG0715@1|root,COG0715@2|Bacteria,1UR7E@1239|Firmicutes,249SE@186801|Clostridia,36EDF@31979|Clostridiaceae	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family	ssuA	-	-	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	NMT1,NMT1_2
SRR25158527_k127_84467_1	1121939.L861_15685	2.545e-05	50.0	COG0715@1|root,COG0715@2|Bacteria,1N40U@1224|Proteobacteria,1SG8D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
SRR25158527_k127_84467_0	710686.Mycsm_03169	2.139e-34	144.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_848929_2	1298867.AUES01000055_gene4815	8.465e-11	70.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2TRY8@28211|Alphaproteobacteria,3K1D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
SRR25158527_k127_848929_0	717785.HYPMC_0264	1.334e-135	447.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
SRR25158527_k127_848929_1	189753.AXAS01000041_gene2534	4.076e-100	336.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
SRR25158527_k127_849802_0	247633.GP2143_12991	1.792e-81	284.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1S0H1@1236|Gammaproteobacteria,1JBTT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Zn-dependent alcohol dehydrogenases	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_851232_1	596152.DesU5LDRAFT_0473	1.348e-45	175.0	COG0715@1|root,COG0715@2|Bacteria,1MZ8F@1224|Proteobacteria,42Q55@68525|delta/epsilon subdivisions,2WK81@28221|Deltaproteobacteria,2MAAX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_851232_0	671143.DAMO_3021	1.136e-60	218.0	COG1496@1|root,COG1496@2|Bacteria,2NPT5@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158527_k127_851666_0	1379698.RBG1_1C00001G0467	1.935e-117	390.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SRR25158527_k127_852508_2	443144.GM21_0895	9.644e-66	230.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158527_k127_852508_0	909663.KI867150_gene2383	1.14e-90	314.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2MQBB@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Mur ligase, middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
SRR25158527_k127_852508_1	316067.Geob_1869	4.357e-72	271.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
SRR25158527_k127_852508_3	32057.KB217478_gene1912	3.516e-06	55.0	COG1216@1|root,COG1216@2|Bacteria,1G4BQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158527_k127_852697_2	311424.DhcVS_1083	2.762e-12	72.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158527_k127_852697_0	439235.Dalk_1952	3.652e-132	434.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MN11@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
SRR25158527_k127_852697_1	263820.PTO0840	4.282e-75	256.0	COG0443@1|root,arCOG03060@2157|Archaea,2XT86@28890|Euryarchaeota,241JG@183967|Thermoplasmata	183967|Thermoplasmata	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158527_k127_859749_2	56780.SYN_01000	1.513e-71	247.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158527_k127_859749_4	290397.Adeh_0752	1.113e-44	177.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,42S5S@68525|delta/epsilon subdivisions,2WNSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
SRR25158527_k127_859749_1	1123072.AUDH01000002_gene2353	4.967e-93	318.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Methionine synthase	MA20_07800	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
SRR25158527_k127_859749_3	338963.Pcar_1431	2.003e-63	223.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,43SGN@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphoribosyl transferase domain	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158527_k127_859749_5	404589.Anae109_1296	1.198e-43	165.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SRR25158527_k127_859749_0	1123234.AUKI01000020_gene859	3.487e-139	454.0	COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,1HZ6B@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRR25158527_k127_861585_3	604354.TSIB_1710	6.074e-12	68.0	arCOG03911@1|root,arCOG03911@2157|Archaea,2Y7IE@28890|Euryarchaeota,244G7@183968|Thermococci	183968|Thermococci	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
SRR25158527_k127_861585_1	504728.K649_10820	3.207e-21	100.0	COG0517@1|root,COG0517@2|Bacteria,1WMQJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
SRR25158527_k127_861585_2	1121428.DESHY_20063___1	5.976e-13	77.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,25ESC@186801|Clostridia,267BX@186807|Peptococcaceae	186801|Clostridia	S	pfam cbs	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158527_k127_861585_0	1123368.AUIS01000038_gene38	1.914e-66	232.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,2NCU9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158527_k127_863186_0	251229.Chro_3721	1.124e-106	366.0	COG2141@1|root,COG2141@2|Bacteria,1G2KI@1117|Cyanobacteria,3VME4@52604|Pleurocapsales	1117|Cyanobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_863186_1	195250.CM001776_gene2577	3.638e-35	153.0	COG0318@1|root,COG0318@2|Bacteria,1GQE8@1117|Cyanobacteria,1H02N@1129|Synechococcus	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158527_k127_866770_1	1122915.AUGY01000020_gene6479	7.985e-19	97.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
SRR25158527_k127_866770_0	257310.BB0084	3.241e-22	101.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,3T63G@506|Alcaligenaceae	28216|Betaproteobacteria	F	Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline	trzA	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
SRR25158527_k127_877712_2	1499967.BAYZ01000103_gene3741	8.236e-58	209.0	COG1032@1|root,COG1032@2|Bacteria,2NQ35@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
SRR25158527_k127_877712_0	870187.Thini_1981	1.183e-137	456.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RPVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	creC	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031667,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07641,ko:K07711	ko02020,ko02024,map02020,map02024	M00449,M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_3,sCache_3_2
SRR25158527_k127_877712_1	998674.ATTE01000001_gene3533	1.826e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMD0@1236|Gammaproteobacteria,460H6@72273|Thiotrichales	72273|Thiotrichales	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158527_k127_877712_3	1396418.BATQ01000007_gene1447	3.969e-39	152.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
SRR25158527_k127_88366_2	644968.DFW101_2101	0.0002749	50.0	28IX5@1|root,2Z8V5@2|Bacteria,1R5YH@1224|Proteobacteria,42NTD@68525|delta/epsilon subdivisions,2WM4I@28221|Deltaproteobacteria,2MAGN@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_88366_1	1042326.AZNV01000012_gene1943	1.217e-92	321.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,4BAT1@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158527_k127_888407_0	429009.Adeg_1824	4.843e-202	647.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SRR25158527_k127_888407_1	485913.Krac_12067	1.536e-22	102.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
SRR25158527_k127_894386_1	1313172.YM304_38470	3.131e-35	143.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	1.3.1.34,3.1.2.6	ko:K00219,ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,Lactamase_B,Rhodanese
SRR25158527_k127_894386_0	861299.J421_3809	4.098e-172	552.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158527_k127_895372_0	1134474.O59_000985	7.713e-62	228.0	COG2503@1|root,COG2503@2|Bacteria,1RB4N@1224|Proteobacteria,1SB1V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acid phosphatase	lppC	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
SRR25158527_k127_895372_1	693661.Arcve_0808	2.733e-09	67.0	COG2141@1|root,arCOG02410@2157|Archaea,2XTN9@28890|Euryarchaeota,245QK@183980|Archaeoglobi	183980|Archaeoglobi	C	Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT	mer	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
SRR25158527_k127_901285_4	290315.Clim_0296	8.045e-08	56.0	COG0695@1|root,COG0695@2|Bacteria,1FEC4@1090|Chlorobi	1090|Chlorobi	O	glutaredoxin 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158527_k127_901285_5	1286170.RORB6_05865	0.0002377	46.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNUC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158527_k127_901285_0	1125863.JAFN01000001_gene559	3.454e-232	733.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SRR25158527_k127_901285_2	1340493.JNIF01000003_gene1436	7.69e-143	472.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
SRR25158527_k127_901285_1	671143.DAMO_2494	6.748e-178	577.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158527_k127_901285_3	861299.J421_2658	3.431e-54	200.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
SRR25158527_k127_902234_1	1123306.KB904346_gene1197	5.776e-13	74.0	COG3576@1|root,COG3576@2|Bacteria,1V4U5@1239|Firmicutes,4I0T5@91061|Bacilli	91061|Bacilli	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158527_k127_902234_0	1120972.AUMH01000002_gene2761	3.23e-117	387.0	2C1EV@1|root,33RW1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158527_k127_906603_1	326424.FRAAL5270	7.552e-19	96.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4EUGS@85013|Frankiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158527_k127_906603_0	604331.AUHY01000064_gene643	7.542e-87	295.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rfbD	-	1.1.1.133,5.1.3.13,5.1.3.26	ko:K00067,ko:K01790,ko:K19997	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158527_k127_909454_0	1303518.CCALI_00831	1.962e-114	378.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158527_k127_910726_2	1232410.KI421424_gene1723	6.004e-100	331.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158527_k127_910726_0	338966.Ppro_2604	2.703e-321	1003.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,43T3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158527_k127_910726_4	443143.GM18_3748	5.884e-71	251.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43UHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158527_k127_910726_3	443143.GM18_4083	4.858e-86	291.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158527_k127_910726_6	439235.Dalk_3936	1.865e-20	96.0	COG1371@1|root,COG1371@2|Bacteria,1NCP6@1224|Proteobacteria,42VQE@68525|delta/epsilon subdivisions,2WS6C@28221|Deltaproteobacteria,2MM59@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158527_k127_910726_1	330214.NIDE3049	2.242e-164	530.0	COG1078@1|root,COG1078@2|Bacteria,3J0YB@40117|Nitrospirae	40117|Nitrospirae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SRR25158527_k127_910726_5	926550.CLDAP_40360	1.489e-63	225.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158527_k127_914539_2	1313172.YM304_40560	3.644e-06	54.0	COG2141@1|root,COG2141@2|Bacteria,2GJ3B@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_3544 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158527_k127_914539_0	290512.Paes_1450	2.543e-65	228.0	COG1943@1|root,COG1943@2|Bacteria,1FF47@1090|Chlorobi	1090|Chlorobi	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
SRR25158527_k127_914539_1	710686.Mycsm_01832	9.854e-64	232.0	COG2358@1|root,COG2358@2|Bacteria,2I9QR@201174|Actinobacteria	201174|Actinobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
SRR25158527_k127_914539_3	298653.Franean1_4514	0.000171	44.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4ERG3@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_922665_1	246194.CHY_0976	2.032e-84	286.0	COG0663@1|root,COG1209@1|root,COG0663@2|Bacteria,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,42GRF@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158527_k127_922665_2	247490.KSU1_D0777	1.681e-67	235.0	COG1898@1|root,COG1898@2|Bacteria,2IZMV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158527_k127_922665_0	234267.Acid_6228	8.231e-121	397.0	COG1088@1|root,COG1088@2|Bacteria,3Y3E7@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158527_k127_922665_3	604331.AUHY01000064_gene643	1.912e-63	225.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rfbD	-	1.1.1.133,5.1.3.13,5.1.3.26	ko:K00067,ko:K01790,ko:K19997	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158527_k127_924061_2	204669.Acid345_4487	8.932e-48	175.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria,2JI3W@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158527_k127_924061_0	1038859.AXAU01000008_gene2022	2.949e-156	504.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158527_k127_924061_1	1000565.METUNv1_04019	3.467e-92	304.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,2KU8A@206389|Rhodocyclales	28216|Betaproteobacteria	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
SRR25158527_k127_925222_0	1244869.H261_21094	2.42e-50	196.0	COG0747@1|root,COG0747@2|Bacteria,1MUP8@1224|Proteobacteria,2TQXX@28211|Alphaproteobacteria,2JQIA@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158527_k127_925306_1	1121405.dsmv_2433	2.677e-26	118.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MISR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SRR25158527_k127_925306_0	1121413.JMKT01000008_gene1198	1.594e-62	224.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2M8RD@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158527_k127_935407_0	671143.DAMO_2373	1.804e-225	706.0	COG1012@1|root,COG1012@2|Bacteria,2NNW6@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158527_k127_935407_1	289376.THEYE_A1385	6.394e-89	297.0	COG0689@1|root,COG0689@2|Bacteria,3J0B8@40117|Nitrospirae	40117|Nitrospirae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158527_k127_936459_0	502025.Hoch_5093	3.697e-30	131.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158527_k127_936459_1	1202768.JROF01000013_gene891	4.864e-07	61.0	COG0697@1|root,arCOG00272@2157|Archaea,2XUHA@28890|Euryarchaeota,23UY1@183963|Halobacteria	183963|Halobacteria	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_940677_0	1278073.MYSTI_03239	2.885e-107	356.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,2YTW5@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158527_k127_940677_1	667014.Thein_1412	9.98e-71	249.0	COG0149@1|root,COG0149@2|Bacteria,2GGX1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158527_k127_940677_2	56780.SYN_03791	1.202e-19	97.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2MS60@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158527_k127_943383_2	1230476.C207_02861	1.119e-16	80.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,3JQN6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HAMP
SRR25158527_k127_943383_0	479434.Sthe_2205	1.032e-57	218.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	2|Bacteria	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_943383_1	1207063.P24_16225	6.461e-41	159.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TQR9@28211|Alphaproteobacteria,2JZNC@204441|Rhodospirillales	204441|Rhodospirillales	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
SRR25158527_k127_945503_1	472759.Nhal_0374	1.448e-32	146.0	COG2208@1|root,COG3829@1|root,COG3852@1|root,COG2208@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,1QW3X@1224|Proteobacteria,1RM9S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KNT	COG2202 FOG PAS PAC domain	-	-	3.1.3.3	ko:K03406,ko:K07315	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035,ko03021	-	-	-	MCPsignal,PAS,PAS_9,SpoIIE
SRR25158527_k127_945503_0	671143.DAMO_0478	7.598e-46	188.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	vncS	-	2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3	ko:K07315,ko:K07641,ko:K10819,ko:K13924	ko02020,ko02030,map02020,map02030	M00449,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SRR25158527_k127_955887_3	665571.STHERM_c18670	5.813e-05	54.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
SRR25158527_k127_955887_2	1046724.KB889898_gene3423	7.064e-06	58.0	COG0810@1|root,COG0810@2|Bacteria,1PEER@1224|Proteobacteria,1RPPU@1236|Gammaproteobacteria,468N3@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	Chalcone_3,TonB_2,TonB_C
SRR25158527_k127_955887_0	862908.BMS_1026	3.423e-27	119.0	COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,42TPM@68525|delta/epsilon subdivisions,2WW8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SRR25158527_k127_955887_1	862908.BMS_1027	7.394e-24	106.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2MTD6@213481|Bdellovibrionales,2WRCE@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SRR25158527_k127_956062_6	768671.ThimaDRAFT_0348	4.774e-13	75.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales	135613|Chromatiales	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
SRR25158527_k127_956062_5	671143.DAMO_1644	1.498e-42	162.0	COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria	2|Bacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
SRR25158527_k127_956062_4	243231.GSU2259	1.789e-46	177.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
SRR25158527_k127_956062_0	706587.Desti_3113	1.765e-179	580.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MQ69@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158527_k127_956062_1	56780.SYN_01565	6.109e-102	344.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MQCW@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SRR25158527_k127_956062_2	1232410.KI421414_gene2842	3.596e-101	338.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158527_k127_956062_3	880072.Desac_2714	2.472e-47	175.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
SRR25158527_k127_95794_0	1380347.JNII01000005_gene3109	4.909e-63	225.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,4ERS6@85013|Frankiales	201174|Actinobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158527_k127_95794_1	1231391.AMZF01000068_gene2180	1.587e-30	131.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,3T4Q9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
SRR25158527_k127_958443_1	1121918.ARWE01000001_gene1263	2.559e-38	145.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,43RYG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	KH domain	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158527_k127_958443_0	243231.GSU2225	6.267e-132	437.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,43U5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SRR25158527_k127_958443_2	582515.KR51_00018850	4.577e-05	51.0	COG0758@1|root,COG0758@2|Bacteria,1G1EN@1117|Cyanobacteria	1117|Cyanobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
SRR25158527_k127_96169_2	1131269.AQVV01000106_gene2306	7.749e-10	64.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
SRR25158527_k127_96169_1	1205680.CAKO01000029_gene5271	2.734e-106	365.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2U2SV@28211|Alphaproteobacteria,2JZPJ@204441|Rhodospirillales	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158527_k127_96169_0	1173025.GEI7407_3200	5.694e-212	670.0	COG1231@1|root,COG1231@2|Bacteria,1G18A@1117|Cyanobacteria,1H6YY@1150|Oscillatoriales	1117|Cyanobacteria	E	Monoamine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158527_k127_964572_0	443143.GM18_3891	3.04e-96	329.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,43TX6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158527_k127_964572_1	880072.Desac_0600	1.335e-25	107.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2MQC4@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
SRR25158527_k127_972862_2	710685.MycrhN_4733	9.075e-11	69.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,23625@1762|Mycobacteriaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158527_k127_972862_1	1231391.AMZF01000003_gene3115	2.583e-80	275.0	COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2W95G@28216|Betaproteobacteria,3T7RQ@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158527_k127_972862_0	1380390.JIAT01000010_gene3810	4.452e-87	300.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	adh	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_972862_3	1231391.AMZF01000014_gene2432	0.0008628	49.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
SRR25158527_k127_97763_0	1205680.CAKO01000040_gene743	6.035e-47	179.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	MA20_07390	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158527_k127_97763_1	525904.Tter_1099	2.197e-13	78.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158527_k127_977712_1	1118054.CAGW01000032_gene741	1.324e-33	134.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
SRR25158527_k127_977712_2	338963.Pcar_2198	2.037e-29	128.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,43SIM@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	POTRA domain, FtsQ-type	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158527_k127_977712_0	404589.Anae109_3893	1.7e-57	202.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SRR25158527_k127_979103_1	443152.MDG893_15060	1.376e-08	65.0	COG3181@1|root,COG3181@2|Bacteria,1RJGP@1224|Proteobacteria,1SZ9G@1236|Gammaproteobacteria,46CCT@72275|Alteromonadaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_979103_0	644282.Deba_0317	1.19e-29	127.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
SRR25158527_k127_979284_1	321846.PS417_18545	4.089e-05	51.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
SRR25158527_k127_979284_0	706587.Desti_3172	6.466e-107	354.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42Q8T@68525|delta/epsilon subdivisions,2WKQE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
SRR25158527_k127_985423_1	1236959.BAMT01000005_gene51	7.305e-27	115.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,2W7ZA@28216|Betaproteobacteria,2KMVH@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158527_k127_985423_0	398767.Glov_1756	1.299e-74	265.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,43UG1@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	TIGRFAM phosphoenolpyruvate-protein phosphotransferase	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158527_k127_986556_0	1122604.JONR01000027_gene3068	1.395e-197	619.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1X3UT@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	adhC	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158527_k127_986556_2	469371.Tbis_2229	5.622e-57	202.0	COG2080@1|root,COG2080@2|Bacteria,2GMYH@201174|Actinobacteria,4E4KI@85010|Pseudonocardiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158527_k127_986556_1	309801.trd_A0566	1.534e-62	226.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158527_k127_988832_1	1509405.GV67_12630	4.545e-49	189.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria,2UDSB@28211|Alphaproteobacteria,4BAAR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
SRR25158527_k127_988832_0	497964.CfE428DRAFT_4013	7.107e-161	516.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
SRR25158527_k127_991287_0	1459636.NTE_02180	9.201e-83	278.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158527_k127_991287_1	350688.Clos_0400	1.601e-44	173.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia,36DKH@31979|Clostridiaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158527_k127_991287_2	580331.Thit_2380	4.867e-36	143.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,42GRT@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158527_k127_991287_3	443143.GM18_2629	2.794e-31	135.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,43V0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
SRR25158527_k127_991287_4	335543.Sfum_3187	3.424e-24	105.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,2MS6A@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
## 2769 queries scanned
## Total time (seconds): 5.985403776168823
## Rate: 462.63 q/s