## Mon Dec 15 18:40:20 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/SRR25158535_bin.1.fa -m mmseqs --itype genome -o SRR25158535_bin.1 --output_dir /data/result/bins/wyx/egg/SRR25158535_bin.1 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SRR25158535_k127_1018601_3	882.DVU_1603	3.598e-50	183.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2M9ZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SRR25158535_k127_1018601_1	502025.Hoch_2002	1.174e-94	319.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_1018601_2	502025.Hoch_2001	4.162e-62	238.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z3A1@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_1018601_0	502025.Hoch_2000	3.222e-215	694.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRR25158535_k127_1020022_1	390989.JOEG01000006_gene808	1.733e-27	129.0	2BS0P@1|root,32M18@2|Bacteria,2HWUX@201174|Actinobacteria,4DKEX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1020022_0	390989.JOEG01000002_gene4261	2.593e-82	289.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DA3D@85008|Micromonosporales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158535_k127_1020940_9	290397.Adeh_3099	3.549e-30	122.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,42T50@68525|delta/epsilon subdivisions,2WPVV@28221|Deltaproteobacteria,2YUY1@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SRR25158535_k127_1020940_2	479432.Sros_0391	4.713e-169	542.0	COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4EFPY@85012|Streptosporangiales	201174|Actinobacteria	G	Fructose-bisphosphate aldolase class-II	fba	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SRR25158535_k127_1020940_7	1306406.ASHX01000002_gene4849	2.397e-43	170.0	29132@1|root,2ZNQK@2|Bacteria,2IRWX@201174|Actinobacteria	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SRR25158535_k127_1020940_0	68219.JNXI01000054_gene182	0.0	1116.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SRR25158535_k127_1020940_4	570268.ANBB01000079_gene4452	1.454e-114	388.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4EFM2@85012|Streptosporangiales	201174|Actinobacteria	F	Lyase	pcaB	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158535_k127_1020940_5	1449976.KALB_2211	4.987e-70	253.0	COG3485@1|root,COG3485@2|Bacteria,2GZGT@201174|Actinobacteria,4E3M4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase alpha subunit	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
SRR25158535_k127_1020940_3	263358.VAB18032_19725	3.284e-120	395.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,4D92V@85008|Micromonosporales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
SRR25158535_k127_1020940_1	1464048.JNZS01000007_gene4483	2.075e-172	548.0	COG0654@1|root,COG0654@2|Bacteria,2GM48@201174|Actinobacteria,4DA82@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
SRR25158535_k127_1020940_8	1246995.AFR_42755	1.767e-40	173.0	2E6RN@1|root,331BS@2|Bacteria,2GME4@201174|Actinobacteria,4DE0N@85008|Micromonosporales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158535_k127_1020940_10	477641.MODMU_1171	9.646e-25	119.0	COG1277@1|root,COG1277@2|Bacteria,2GVAC@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158535_k127_1020940_6	263358.VAB18032_10945	4.31e-51	187.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4DAX5@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1023606_2	33876.JNXY01000010_gene2499	5.717e-45	168.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DC7R@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1023606_0	1122182.KB903838_gene4184	1.032e-99	340.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria,4DCXD@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_1023606_1	390989.JOEG01000004_gene3753	3.679e-54	210.0	COG5002@1|root,COG5002@2|Bacteria,2GMH4@201174|Actinobacteria,4DAGR@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	baeS	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_1023606_3	1304865.JAGF01000001_gene399	4.241e-13	69.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4F0QK@85016|Cellulomonadaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1024258_4	644966.Tmar_1474	2.322e-47	180.0	COG0074@1|root,COG0074@2|Bacteria,1UJ4F@1239|Firmicutes,24AQG@186801|Clostridia	186801|Clostridia	C	Succinyl-CoA synthetase, alpha subunit	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
SRR25158535_k127_1024258_3	1123024.AUII01000015_gene3739	3.836e-51	184.0	COG5646@1|root,COG5646@2|Bacteria,2I3RY@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158535_k127_1024258_0	1122611.KB903961_gene4422	1.056e-97	344.0	COG2273@1|root,COG2273@2|Bacteria,2GTJC@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SRR25158535_k127_1024258_2	469383.Cwoe_0904	3.922e-57	202.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria,4CT04@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_1024258_6	525909.Afer_1449	0.0007176	53.0	2CC95@1|root,31D2W@2|Bacteria,2HGQY@201174|Actinobacteria,4CNT8@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1024258_1	543632.JOJL01000015_gene8728	2.145e-74	259.0	2D3F0@1|root,32TEU@2|Bacteria,2IDGD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1024258_5	1120949.KB903296_gene9609	5.396e-08	57.0	2D3F0@1|root,32TEU@2|Bacteria,2IDGD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1026828_2	1289387.AUKW01000023_gene2970	6.003e-86	297.0	COG0613@1|root,COG0613@2|Bacteria,2IDTP@201174|Actinobacteria	201174|Actinobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
SRR25158535_k127_1026828_3	365528.KB891262_gene5080	1.1e-80	275.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4EWG8@85013|Frankiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
SRR25158535_k127_1026828_4	35754.JNYJ01000046_gene3117	7.063e-80	288.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4DBFZ@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyltransferase like family 2	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158535_k127_1026828_5	1223543.GP2_009_00420	3.339e-53	209.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,4GAFF@85026|Gordoniaceae	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070085,GO:0071704,GO:0071944,GO:0075136,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	iNJ661.Rv2051c	CN_hydrolase
SRR25158535_k127_1026828_9	1283287.KB822576_gene3668	4.449e-14	76.0	2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria,4DWJ0@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4193)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4193
SRR25158535_k127_1026828_7	861299.J421_2697	5.091e-30	140.0	COG0419@1|root,COG0419@2|Bacteria,1ZTD9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
SRR25158535_k127_1026828_10	1206744.BAGL01000002_gene4110	1.732e-08	69.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,4FW18@85025|Nocardiaceae	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158535_k127_1026828_6	456442.Mboo_0940	3.963e-32	140.0	COG0420@1|root,arCOG00397@2157|Archaea,2XT7A@28890|Euryarchaeota,2NA2J@224756|Methanomicrobia	224756|Methanomicrobia	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity	mre11	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
SRR25158535_k127_1026828_0	926560.KE387025_gene4008	6.578e-135	459.0	COG0675@1|root,COG0675@2|Bacteria,1WIJR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1026828_1	1379698.RBG1_1C00001G1269	5.244e-122	409.0	COG0433@1|root,COG0433@2|Bacteria,2NPZD@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF87	-	-	-	ko:K06915,ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,PLDc_2
SRR25158535_k127_1026828_8	1379698.RBG1_1C00001G1269	1.257e-17	97.0	COG0433@1|root,COG0433@2|Bacteria,2NPZD@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function DUF87	-	-	-	ko:K06915,ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,PLDc_2
SRR25158535_k127_1035422_0	365528.KB891208_gene3040	1.218e-176	558.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4ERNR@85013|Frankiales	201174|Actinobacteria	HP	PFAM UBA THIF-type NAD FAD binding	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158535_k127_1035422_3	478801.Ksed_19130	3.172e-27	115.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria,1ZW7M@145357|Dermacoccaceae	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	-	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
SRR25158535_k127_1035422_1	1352941.M877_17665	1.516e-119	391.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100,1.1.1.69	ko:K00046,ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_1035422_6	1120948.KB903221_gene401	2.493e-07	54.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4E1SM@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_1035422_2	457425.XNR_0050	5.975e-33	132.0	COG1695@1|root,COG1695@2|Bacteria,2IQ70@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator padr family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_1035422_4	2074.JNYD01000006_gene1626	4.649e-13	74.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4E08C@85010|Pseudonocardiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158535_k127_1039192_4	1122939.ATUD01000007_gene2092	2.415e-18	86.0	COG2060@1|root,COG2060@2|Bacteria,2GK51@201174|Actinobacteria,4CRJ1@84995|Rubrobacteria	84995|Rubrobacteria	P	Potassium-transporting ATPase A subunit	-	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRR25158535_k127_1039192_0	1382356.JQMP01000003_gene1959	2.575e-87	307.0	COG0642@1|root,COG2205@2|Bacteria,2GAAW@200795|Chloroflexi,27Z8B@189775|Thermomicrobia	189775|Thermomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158535_k127_1039192_1	1121927.GOHSU_46_00230	1.581e-73	262.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4GCR1@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	GO:0008150,GO:0040007	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1039192_2	1128421.JAGA01000002_gene344	5.217e-58	209.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158535_k127_1039192_3	710111.FraQA3DRAFT_2968	1.284e-48	184.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4ERNZ@85013|Frankiales	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158535_k127_1039192_5	436229.JOEH01000009_gene4564	0.0005809	42.0	COG1609@1|root,COG1609@2|Bacteria,2GSWK@201174|Actinobacteria,2NJKA@228398|Streptacidiphilus	201174|Actinobacteria	K	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Phage_int_SAM_3,Phage_integrase
SRR25158535_k127_1040210_1	1089545.KB913037_gene8465	3.397e-74	253.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_1040210_3	1123023.JIAI01000003_gene2582	9.154e-12	69.0	COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4E81J@85010|Pseudonocardiales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158535_k127_1040210_2	1121946.AUAX01000003_gene1632	3.812e-56	209.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158535_k127_1040210_0	219305.MCAG_04342	2.218e-86	296.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DBZU@85008|Micromonosporales	201174|Actinobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158535_k127_1043091_0	1128421.JAGA01000002_gene1381	8.65e-104	355.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
SRR25158535_k127_1043961_1	656024.FsymDg_4476	3.55e-74	262.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_1043961_0	1116232.AHBF01000015_gene3646	1.218e-88	313.0	COG3267@1|root,COG3267@2|Bacteria,2GMRH@201174|Actinobacteria	201174|Actinobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1045295_10	298653.Franean1_5090	6.828e-11	67.0	COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria	201174|Actinobacteria	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
SRR25158535_k127_1045295_8	1283299.AUKG01000002_gene4919	3.613e-36	142.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4CQ0C@84995|Rubrobacteria	84995|Rubrobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
SRR25158535_k127_1045295_7	867903.ThesuDRAFT_01649	1.67e-48	183.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WCI6@538999|Clostridiales incertae sedis	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SRR25158535_k127_1045295_6	593907.Celgi_1991	1.744e-50	190.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4F1BJ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SRR25158535_k127_1045295_0	1352941.M877_31480	1.093e-162	523.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SRR25158535_k127_1045295_9	1172186.KB911473_gene5495	4.186e-17	92.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,233TS@1762|Mycobacteriaceae	201174|Actinobacteria	D	cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
SRR25158535_k127_1045295_5	555088.DealDRAFT_1345	1.624e-51	206.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,42JQC@68298|Syntrophomonadaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SRR25158535_k127_1045295_1	469371.Tbis_1408	2.848e-117	411.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4DYX2@85010|Pseudonocardiales	201174|Actinobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_1045295_4	1449068.JMLQ01000004_gene1405	1.426e-69	267.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4FXCK@85025|Nocardiaceae	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SRR25158535_k127_1045295_3	1048339.KB913029_gene4577	7.685e-91	320.0	COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4ES9A@85013|Frankiales	201174|Actinobacteria	D	Belongs to the SEDS family	ftsW	GO:0008150,GO:0040007	2.4.1.227	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	2.A.103.1	GT28	-	FTSW_RODA_SPOVE
SRR25158535_k127_1045295_2	326424.FRAAL2194	3.331e-99	341.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4ERI0@85013|Frankiales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iNJ661.Rv2155c	AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_1048363_1	710686.Mycsm_00378	6.302e-66	245.0	COG2017@1|root,COG2017@2|Bacteria,2HMIG@201174|Actinobacteria,232CA@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
SRR25158535_k127_1048363_0	1121946.AUAX01000018_gene6931	3.184e-120	389.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4DEJ3@85008|Micromonosporales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158535_k127_1049936_7	1298863.AUEP01000011_gene497	3.25e-13	70.0	COG2346@1|root,COG2346@2|Bacteria,2GMG5@201174|Actinobacteria,4DS9G@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
SRR25158535_k127_1049936_5	227882.SAV_3722	3.309e-23	100.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_1049936_3	644282.Deba_0601	7.627e-53	200.0	COG0613@1|root,COG0613@2|Bacteria,1QV9S@1224|Proteobacteria,43BP1@68525|delta/epsilon subdivisions,2X70C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SRR25158535_k127_1049936_2	195250.CM001776_gene717	2.07e-60	214.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1GZWS@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158535_k127_1049936_1	644966.Tmar_1633	2.18e-122	415.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,249ZJ@186801|Clostridia,3WDAR@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158535_k127_1049936_4	28444.JODQ01000011_gene3433	1.445e-25	115.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4EIZZ@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_1049936_6	543632.JOJL01000004_gene4133	2.935e-22	106.0	COG2197@1|root,COG2197@2|Bacteria,2ICWH@201174|Actinobacteria,4DHB5@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_1049936_0	469371.Tbis_2075	3.555e-171	550.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4DYQ5@85010|Pseudonocardiales	201174|Actinobacteria	J	elongation factor G domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SRR25158535_k127_1051294_0	469371.Tbis_1422	0.0	1255.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2I12T@201174|Actinobacteria,4DX7Y@85010|Pseudonocardiales	201174|Actinobacteria	L	UvrD/REP helicase N-terminal domain	pcrA	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
SRR25158535_k127_1065609_2	1304865.JAGF01000001_gene2446	1.595e-44	177.0	29JD5@1|root,306AN@2|Bacteria,2I9J8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1065609_1	1304865.JAGF01000001_gene2445	8.414e-80	285.0	COG0697@1|root,COG0697@2|Bacteria,2IH82@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_1065609_4	469371.Tbis_3231	1.856e-09	61.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria,4E764@85010|Pseudonocardiales	201174|Actinobacteria	O	HupF/HypC family	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SRR25158535_k127_1065609_3	118163.Ple7327_1402	3.536e-15	89.0	COG0680@1|root,COG0680@2|Bacteria,1G7PP@1117|Cyanobacteria,3VKCV@52604|Pleurocapsales	1117|Cyanobacteria	C	TIGRFAM hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1065609_0	926569.ANT_12550	1.828e-165	529.0	COG3259@1|root,COG3259@2|Bacteria,2G68W@200795|Chloroflexi	200795|Chloroflexi	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SRR25158535_k127_1075032_1	644966.Tmar_1233	6.166e-114	378.0	COG0213@1|root,COG0295@1|root,COG0213@2|Bacteria,COG0295@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,3WCD5@538999|Clostridiales incertae sedis	186801|Clostridia	F	Pyrimidine nucleoside phosphorylase C-terminal domain	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158535_k127_1075032_2	264732.Moth_1362	5.899e-46	173.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,42FD9@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM peptidase M50	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SRR25158535_k127_1075032_0	436229.JOEH01000004_gene55	1.132e-245	770.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,2NM7I@228398|Streptacidiphilus	201174|Actinobacteria	J	Aminoacyl-tRNA editing domain	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SRR25158535_k127_1075697_1	673862.BABL1_334	2.178e-62	224.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158535_k127_1075697_2	1463903.JOIZ01000002_gene1264	2.627e-45	174.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria	201174|Actinobacteria	S	regulation of cellular protein catabolic process	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
SRR25158535_k127_1075697_0	526225.Gobs_0795	2.339e-104	357.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4ESBD@85013|Frankiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR25158535_k127_1076827_2	298653.Franean1_0496	7.302e-05	46.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve_3
SRR25158535_k127_1076827_1	1463903.JOIZ01000028_gene5907	9.922e-13	73.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
SRR25158535_k127_1076827_0	931627.MycrhDRAFT_6817	1.336e-35	158.0	COG1752@1|root,COG1752@2|Bacteria,2IAR4@201174|Actinobacteria	201174|Actinobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1085241_1	264732.Moth_1692	5.96e-70	255.0	COG3294@1|root,COG3294@2|Bacteria,1UXSS@1239|Firmicutes,24A8Y@186801|Clostridia,42FRF@68295|Thermoanaerobacterales	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
SRR25158535_k127_1085241_4	35754.JNYJ01000001_gene7410	7.912e-16	82.0	COG1862@1|root,COG1862@2|Bacteria,2IQSP@201174|Actinobacteria,4DFMC@85008|Micromonosporales	201174|Actinobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SRR25158535_k127_1085241_0	591158.SSMG_04232	1.475e-128	432.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SRR25158535_k127_1085241_2	1343740.M271_10380	4.021e-40	164.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SRR25158535_k127_1085241_3	1451261.AS96_13730	8.42e-40	156.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4FNJN@85023|Microbacteriaceae	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SRR25158535_k127_1087049_5	1040982.AXAL01000017_gene5108	2.008e-10	64.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria,43HB6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158535_k127_1087049_4	287986.DV20_41445	1.311e-10	66.0	COG3795@1|root,COG3795@2|Bacteria,2ISB8@201174|Actinobacteria,4EEYV@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_1087049_1	1123024.AUII01000014_gene4295	9.175e-119	391.0	COG3386@1|root,COG3386@2|Bacteria,2HE8D@201174|Actinobacteria,4E2FP@85010|Pseudonocardiales	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
SRR25158535_k127_1087049_0	1122138.AQUZ01000019_gene8120	1.366e-143	466.0	29FX3@1|root,302US@2|Bacteria,2IIAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1087049_2	1172188.KB911820_gene2425	1.866e-51	202.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4FH84@85021|Intrasporangiaceae	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1087049_3	35754.JNYJ01000025_gene8888	4.803e-11	73.0	COG3920@1|root,COG3920@2|Bacteria,2IT7M@201174|Actinobacteria,4DF1C@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,STAS_2
SRR25158535_k127_1087049_6	1278073.MYSTI_05838	1.932e-09	63.0	COG1680@1|root,COG1680@2|Bacteria,1R653@1224|Proteobacteria,43ARW@68525|delta/epsilon subdivisions,2X65Z@28221|Deltaproteobacteria,2Z0S3@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
SRR25158535_k127_1092525_4	243164.DET0739	4.149e-20	92.0	COG0436@1|root,COG0436@2|Bacteria,2G60K@200795|Chloroflexi,34D2W@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158535_k127_1092525_0	656024.FsymDg_3604	1.572e-159	515.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4ERJ5@85013|Frankiales	201174|Actinobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SRR25158535_k127_1092525_1	211114.JOEF01000004_gene6659	2.431e-70	244.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4E040@85010|Pseudonocardiales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158535_k127_1092525_5	1451261.AS96_06645	1.233e-11	70.0	COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria,4FQ73@85023|Microbacteriaceae	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SRR25158535_k127_1092525_3	1121422.AUMW01000005_gene639	4.503e-41	167.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,261UI@186807|Peptococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SRR25158535_k127_1092525_2	525909.Afer_1025	1.863e-55	199.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SRR25158535_k127_1097194_5	1449048.JQKU01000025_gene3932	7.04e-26	114.0	COG2206@1|root,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,235GC@1762|Mycobacteriaceae	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD_5
SRR25158535_k127_1097194_1	1463821.JOGR01000002_gene614	1.802e-84	286.0	COG0596@1|root,COG0596@2|Bacteria,2GJ4I@201174|Actinobacteria,4F00U@85014|Glycomycetales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158535_k127_1097194_6	1206101.AZXC01000007_gene2441	2.87e-15	78.0	COG0346@1|root,COG0346@2|Bacteria,2I6JC@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_4a
SRR25158535_k127_1097194_2	1133850.SHJG_8471	4.159e-79	269.0	COG2154@1|root,COG2154@2|Bacteria,2IHZE@201174|Actinobacteria	201174|Actinobacteria	H	dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158535_k127_1097194_0	457429.ABJI02000843_gene3305	7.345e-89	301.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158535_k127_1097194_4	1056816.JAFQ01000004_gene5476	1.309e-43	169.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
SRR25158535_k127_1097194_3	1122609.AUGT01000029_gene2640	2.332e-62	218.0	COG0702@1|root,COG0702@2|Bacteria,2HVU1@201174|Actinobacteria,4DTYQ@85009|Propionibacteriales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158535_k127_109784_0	298655.KI912266_gene3656	1.612e-162	522.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4ERN8@85013|Frankiales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
SRR25158535_k127_109784_1	1079986.JH164866_gene2808	6.123e-08	56.0	2E9C2@1|root,333JS@2|Bacteria,2IQ5V@201174|Actinobacteria	201174|Actinobacteria	S	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
SRR25158535_k127_1113736_4	1229780.BN381_310078	5.452e-72	252.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158535_k127_1113736_6	219305.MCAG_01913	2.008e-50	181.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4DEJ5@85008|Micromonosporales	201174|Actinobacteria	C	4Fe-4S binding domain	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4
SRR25158535_k127_1113736_7	272560.BPSL1102	5.005e-47	182.0	COG0697@1|root,COG0697@2|Bacteria,1NFUD@1224|Proteobacteria,2VRN9@28216|Betaproteobacteria,1KFDS@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_1113736_11	1246474.ANBE01000009_gene350	5.906e-05	52.0	COG0454@1|root,COG0456@2|Bacteria,2I3UD@201174|Actinobacteria,4EKTF@85012|Streptosporangiales	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1113736_1	479432.Sros_8442	1.548e-147	481.0	COG0215@1|root,COG0215@2|Bacteria,2IDHB@201174|Actinobacteria,4EN5K@85012|Streptosporangiales	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
SRR25158535_k127_1113736_3	469371.Tbis_1280	3.658e-81	277.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4E7TG@85010|Pseudonocardiales	201174|Actinobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158535_k127_1113736_9	67315.JOBD01000013_gene6984	3.22e-25	119.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1113736_2	479432.Sros_2658	1.347e-120	394.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4EGS5@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158535_k127_1113736_5	561175.KB894094_gene1456	5.061e-58	220.0	arCOG04740@1|root,31PZA@2|Bacteria,2GP15@201174|Actinobacteria,4EIMY@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1113736_0	28444.JODQ01000004_gene6320	1.773e-237	760.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4EH5T@85012|Streptosporangiales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158535_k127_1113736_10	670487.Ocepr_1770	8.841e-25	117.0	COG0438@1|root,COG0438@2|Bacteria,1WIYM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SRR25158535_k127_1113736_8	1121472.AQWN01000014_gene642	8.418e-45	169.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SRR25158535_k127_1147389_1	1894.JOER01000023_gene7344	7.177e-35	152.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158535_k127_1147389_0	1122138.AQUZ01000011_gene4987	1.464e-75	267.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4DP94@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158535_k127_1148763_1	543632.JOJL01000011_gene6959	1.349e-19	97.0	COG3920@1|root,COG3920@2|Bacteria,2IT7M@201174|Actinobacteria,4DF1C@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,STAS_2
SRR25158535_k127_1148763_0	1380390.JIAT01000011_gene2341	3.022e-104	359.0	COG4988@1|root,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria,4CPT3@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_1149227_1	105559.Nwat_1530	5.517e-94	319.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria,1X06N@135613|Chromatiales	135613|Chromatiales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158535_k127_1149227_2	235985.BBPN01000007_gene3324	2.129e-28	119.0	2DFE0@1|root,2ZRI8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1149227_0	1192034.CAP_5276	1.937e-135	435.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,42PAQ@68525|delta/epsilon subdivisions,2WMYT@28221|Deltaproteobacteria,2Z2BP@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158535_k127_1151054_12	37919.EP51_10430	7.326e-23	100.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4FURR@85025|Nocardiaceae	201174|Actinobacteria	P	Arylsulfatase	atsD	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158535_k127_1151054_9	1229780.BN381_350140	1.838e-30	128.0	COG2161@1|root,COG2161@2|Bacteria,2GV08@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	relB	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
SRR25158535_k127_1151054_10	1122622.ATWJ01000010_gene1302	3.066e-25	111.0	COG2026@1|root,COG2026@2|Bacteria,2GRQR@201174|Actinobacteria,4FHYW@85021|Intrasporangiaceae	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	relE	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SRR25158535_k127_1151054_13	237368.SCABRO_01150	4.106e-14	78.0	COG1487@1|root,COG1487@2|Bacteria,2J1EF@203682|Planctomycetes	203682|Planctomycetes	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158535_k127_1151054_14	1123371.ATXH01000026_gene126	0.0002938	48.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SRR25158535_k127_1151054_1	1120950.KB892790_gene2100	2.438e-202	639.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4DMZ8@85009|Propionibacteriales	201174|Actinobacteria	E	Peptidase dimerisation domain	argE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_1151054_4	1128421.JAGA01000004_gene2704	9.38e-113	384.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158535_k127_1151054_8	134676.ACPL_7690	5.986e-34	138.0	COG0350@1|root,COG0350@2|Bacteria,2IHP1@201174|Actinobacteria,4DD7R@85008|Micromonosporales	201174|Actinobacteria	L	Methyltransferase	ada	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
SRR25158535_k127_1151054_6	1122182.KB903815_gene1532	8.51e-41	158.0	COG1853@1|root,COG1853@2|Bacteria,2IP6R@201174|Actinobacteria,4DCXF@85008|Micromonosporales	201174|Actinobacteria	S	flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SRR25158535_k127_1151054_3	35754.JNYJ01000079_gene4332	1.193e-142	462.0	COG0673@1|root,COG0673@2|Bacteria,2IE7D@201174|Actinobacteria,4DH9M@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
SRR25158535_k127_1151054_5	35754.JNYJ01000043_gene4416	1.649e-71	247.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4DK0U@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1151054_0	1123024.AUII01000006_gene4636	0.0	1061.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4EE9U@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158535_k127_1151054_11	1150398.JIBJ01000004_gene2790	7.054e-24	109.0	COG0845@1|root,COG0845@2|Bacteria,2I53W@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1151054_2	1123024.AUII01000006_gene4636	1.754e-168	537.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4EE9U@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158535_k127_1152067_2	134676.ACPL_4387	2.294e-05	51.0	2CT9V@1|root,32SSX@2|Bacteria,2HS3F@201174|Actinobacteria,4DF67@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158535_k127_1152067_1	1122611.KB903946_gene711	2.244e-25	122.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria,4EIPF@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
SRR25158535_k127_1152067_0	164757.Mjls_5228	1.616e-53	190.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,233MI@1762|Mycobacteriaceae	201174|Actinobacteria	S	associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_1153575_2	1169161.KB897728_gene851	1.6e-18	86.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158535_k127_1153575_4	1382356.JQMP01000001_gene932	5.627e-14	72.0	COG0395@1|root,COG0395@2|Bacteria,2G7QJ@200795|Chloroflexi,27Z38@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158535_k127_1153575_0	479432.Sros_8214	4.092e-102	352.0	COG1028@1|root,COG1028@2|Bacteria,2GK78@201174|Actinobacteria,4EFHP@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158535_k127_1153575_3	680198.SCAB_84311	1.485e-17	89.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158535_k127_1153575_1	1380393.JHVP01000005_gene3547	6.413e-41	154.0	COG5634@1|root,COG5634@2|Bacteria,2GJRH@201174|Actinobacteria,4ETTV@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2278)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2278,LTD
SRR25158535_k127_1160492_1	543632.JOJL01000028_gene168	1.46e-225	720.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4D8Z2@85008|Micromonosporales	201174|Actinobacteria	L	DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158535_k127_1160492_4	2045.KR76_10360	1.629e-30	138.0	COG1316@1|root,COG1316@2|Bacteria,2IAW9@201174|Actinobacteria,4DTHV@85009|Propionibacteriales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158535_k127_1160492_3	68570.DC74_4508	1.124e-44	177.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SRR25158535_k127_1160492_5	1120998.AUFC01000023_gene2163	1.734e-06	56.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,24Q6W@186801|Clostridia	186801|Clostridia	T	anti-sigma B factor	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158535_k127_1160492_0	469371.Tbis_0223	2.407e-266	842.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,4DY9J@85010|Pseudonocardiales	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SRR25158535_k127_1160492_2	521098.Aaci_1381	1.899e-170	552.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,27819@186823|Alicyclobacillaceae	91061|Bacilli	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
SRR25158535_k127_1165098_2	397278.JOJN01000001_gene2725	5.502e-32	125.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4DRPI@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158535_k127_1165098_1	351607.Acel_0114	3.899e-148	478.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4ERX6@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SRR25158535_k127_1165098_0	1394178.AWOO02000003_gene2793	6.845e-194	614.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4EGQ9@85012|Streptosporangiales	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158535_k127_1165098_3	1385519.N801_01975	2.771e-16	86.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4FES5@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATP-dependent Clp protease	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_1168323_0	1122611.KB903941_gene2127	6.436e-203	640.0	COG0119@1|root,COG0119@2|Bacteria,2INFJ@201174|Actinobacteria,4EMCZ@85012|Streptosporangiales	201174|Actinobacteria	E	HMGL-like	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
SRR25158535_k127_1168323_1	1120936.KB907211_gene501	2.131e-107	361.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria,4EN64@85012|Streptosporangiales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
SRR25158535_k127_1168323_4	1229780.BN381_610018	1.161e-32	134.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,3UXIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_1168323_3	1382306.JNIM01000001_gene1358	3.182e-41	164.0	COG0215@1|root,COG1216@1|root,COG0215@2|Bacteria,COG1216@2|Bacteria,2G5Z0@200795|Chloroflexi	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SRR25158535_k127_1168323_5	469371.Tbis_0358	1.432e-28	126.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4E4UR@85010|Pseudonocardiales	201174|Actinobacteria	I	dehydratase	hadB	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
SRR25158535_k127_1168323_2	405948.SACE_6876	3.523e-44	171.0	COG2030@1|root,COG2030@2|Bacteria,2GMVC@201174|Actinobacteria,4E3JC@85010|Pseudonocardiales	201174|Actinobacteria	I	Belongs to the UPF0336 family	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
SRR25158535_k127_1168323_7	479433.Caci_0897	2.139e-21	94.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SRR25158535_k127_1168323_6	1370120.AUWR01000011_gene1084	9.663e-23	97.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,233XN@1762|Mycobacteriaceae	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158535_k127_1175336_4	1449976.KALB_1576	7.568e-09	69.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4DXJ2@85010|Pseudonocardiales	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158535_k127_1175336_0	749927.AMED_8995	6.054e-131	434.0	COG1457@1|root,COG1457@2|Bacteria,2GJ6B@201174|Actinobacteria,4E0TT@85010|Pseudonocardiales	201174|Actinobacteria	F	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
SRR25158535_k127_1175336_2	591158.SSMG_02259	2.571e-36	149.0	COG0454@1|root,COG0456@2|Bacteria,2IRHJ@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_1175336_3	1137268.AZXF01000027_gene2607	3.096e-09	59.0	COG0645@1|root,COG0645@2|Bacteria,2IM2M@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158535_k127_1175336_1	1463934.JOCF01000010_gene4625	1.518e-42	159.0	COG0645@1|root,COG0645@2|Bacteria,2IM2M@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
SRR25158535_k127_1179856_0	266117.Rxyl_0815	1.925e-123	399.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CP9K@84995|Rubrobacteria	84995|Rubrobacteria	F	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
SRR25158535_k127_1179856_1	298653.Franean1_5989	2.179e-46	176.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4ERBR@85013|Frankiales	201174|Actinobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
SRR25158535_k127_1181603_0	1380390.JIAT01000009_gene1659	1.456e-150	480.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4CSAM@84995|Rubrobacteria	84995|Rubrobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158535_k127_1181603_1	219305.MCAG_04341	1.277e-63	233.0	COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,4DBTG@85008|Micromonosporales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158535_k127_119467_0	710696.Intca_3039	2.612e-201	631.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158535_k127_119467_2	710696.Intca_3038	9.947e-137	440.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4FJHH@85021|Intrasporangiaceae	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158535_k127_119467_1	710696.Intca_3037	3.43e-166	538.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158535_k127_119467_4	33876.JNXY01000004_gene1454	1.873e-103	359.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DA7P@85008|Micromonosporales	201174|Actinobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158535_k127_119467_3	710696.Intca_3035	2.786e-106	348.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4FF9V@85021|Intrasporangiaceae	201174|Actinobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158535_k127_119467_5	1267535.KB906767_gene3050	1.597e-56	207.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_119467_6	2002.JOEQ01000007_gene1884	7.804e-46	171.0	COG4420@1|root,COG4420@2|Bacteria,2GJRV@201174|Actinobacteria,4EJ0N@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
SRR25158535_k127_119467_7	1289387.AUKW01000004_gene1330	1.759e-18	87.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria	201174|Actinobacteria	P	transporter mgtE	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRR25158535_k127_1199844_0	1123320.KB889688_gene406	1.347e-101	348.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria	201174|Actinobacteria	C	succinate dehydrogenase	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158535_k127_1199844_3	1283283.ATXA01000007_gene3837	1.444e-39	150.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,4EVBI@85013|Frankiales	201174|Actinobacteria	C	Succinate dehydrogenase hydrophobic	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158535_k127_1199844_2	656024.FsymDg_0997	1.05e-40	154.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria	201174|Actinobacteria	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SRR25158535_k127_1199844_1	526225.Gobs_1813	5.278e-53	209.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4ESF5@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158535_k127_1199844_4	285535.JOEY01000048_gene1652	8.01e-23	101.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1199844_5	525909.Afer_1427	1.925e-21	96.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1202991_2	2074.JNYD01000006_gene1665	3.443e-67	239.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4E4A4@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
SRR25158535_k127_1202991_0	472759.Nhal_2850	2.404e-214	686.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,1RS4U@1236|Gammaproteobacteria,1WWJ9@135613|Chromatiales	135613|Chromatiales	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158535_k127_1202991_1	1122185.N792_08240	2.88e-179	578.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RQE4@1236|Gammaproteobacteria,1X59Z@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158535_k127_1202991_3	1120934.KB894409_gene6564	5.378e-11	67.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4E080@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158535_k127_1205672_2	909613.UO65_0211	3.426e-101	342.0	COG1960@1|root,COG1960@2|Bacteria,2H7DI@201174|Actinobacteria,4DZXM@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_1205672_5	909613.UO65_0213	3.894e-47	192.0	COG2227@1|root,COG2227@2|Bacteria,2ID71@201174|Actinobacteria	2|Bacteria	H	PFAM Methyltransferase type 11	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_1205672_4	994479.GL877878_gene979	4.08e-66	241.0	COG3424@1|root,COG3424@2|Bacteria,2GV0U@201174|Actinobacteria,4E1NP@85010|Pseudonocardiales	201174|Actinobacteria	Q	naringenin-chalcone synthase	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
SRR25158535_k127_1205672_1	656024.FsymDg_3734	1.185e-101	336.0	COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4ERX7@85013|Frankiales	201174|Actinobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
SRR25158535_k127_1205672_0	1121372.AULK01000003_gene257	5.707e-121	400.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4FQ55@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_1205672_3	644966.Tmar_0077	3.33e-99	335.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SRR25158535_k127_1223643_1	446466.Cfla_1682	3.299e-30	121.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4F0IQ@85016|Cellulomonadaceae	201174|Actinobacteria	S	Dynein light intermediate chain (DLIC)	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158535_k127_1223643_3	390989.JOEG01000023_gene5741	5.037e-12	70.0	COG1309@1|root,COG1309@2|Bacteria,2GZ1Y@201174|Actinobacteria,4DDXG@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158535_k127_1223643_2	471853.Bcav_3158	3.397e-30	130.0	2C9IE@1|root,32UBS@2|Bacteria,2INT4@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
SRR25158535_k127_1223643_0	326424.FRAAL2497	1.114e-39	164.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158535_k127_1241848_3	234267.Acid_5182	6.679e-09	63.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158535_k127_1241848_0	446471.Xcel_1211	1.574e-219	711.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4F3HD@85017|Promicromonosporaceae	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158535_k127_1241848_2	1521187.JPIM01000018_gene433	9.573e-16	90.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi,375YN@32061|Chloroflexia	32061|Chloroflexia	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158535_k127_1241848_1	1121877.JQKF01000004_gene1125	1.264e-114	379.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CMPR@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158535_k127_1263558_1	661367.LLO_1326	1.049e-25	119.0	COG0077@1|root,COG0077@2|Bacteria,1PK3E@1224|Proteobacteria,1RXS0@1236|Gammaproteobacteria,1JDA9@118969|Legionellales	118969|Legionellales	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
SRR25158535_k127_1263558_0	351607.Acel_0043	3.749e-42	166.0	COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158535_k127_12649_2	1214101.BN159_4293	1.573e-95	325.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
SRR25158535_k127_12649_1	479434.Sthe_1230	6.41e-141	466.0	COG2072@1|root,COG2072@2|Bacteria	2|Bacteria	P	N,N-dimethylaniline monooxygenase activity	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158535_k127_12649_3	930171.Asphe3_09770	2.621e-22	105.0	COG2020@1|root,COG2020@2|Bacteria,2GTDR@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158535_k127_12649_0	383372.Rcas_4255	2.894e-193	612.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
SRR25158535_k127_12649_4	1137268.AZXF01000046_gene2107	4.78e-10	66.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	ko:K04074,ko:K07484	-	-	-	-	ko00000,ko03036	-	-	-	DDE_Tnp_IS66,DivIVA,NRBF2,zf-IS66
SRR25158535_k127_1271347_3	211165.AJLN01000084_gene1825	6.201e-06	51.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158535_k127_1271347_2	408672.NBCG_04718	2.982e-06	55.0	COG5640@1|root,COG5640@2|Bacteria,2IB3X@201174|Actinobacteria,4DPTD@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158535_k127_1271347_0	351607.Acel_0379	1.229e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158535_k127_1271347_1	345341.KUTG_09210	3.623e-10	71.0	2DRM0@1|root,33C8E@2|Bacteria,2ITBS@201174|Actinobacteria,4E7IG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1271347_4	1089546.AQUI01000002_gene4505	1.736e-05	53.0	2E46R@1|root,32Z2P@2|Bacteria,2GRCW@201174|Actinobacteria,409HV@622450|Actinopolysporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1271372_1	222534.KB893766_gene2938	1.659e-96	320.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_1271372_0	222534.KB893766_gene2938	3.148e-125	409.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_1271563_0	1205910.B005_1130	4.917e-82	281.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4EGIJ@85012|Streptosporangiales	201174|Actinobacteria	F	AICARFT/IMPCHase bienzyme	purH	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SRR25158535_k127_1271563_2	284031.JNXD01000005_gene3397	3.018e-51	186.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158535_k127_1271563_1	749414.SBI_08840	1.333e-73	264.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_1271563_3	479434.Sthe_0994	2.032e-50	184.0	COG0262@1|root,COG0262@2|Bacteria,2G8NF@200795|Chloroflexi	200795|Chloroflexi	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_1276498_2	867845.KI911784_gene3708	3.625e-24	119.0	COG3437@1|root,COG3437@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD_5,Response_reg
SRR25158535_k127_1276498_1	1394178.AWOO02000005_gene3606	5.625e-51	198.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_1276498_4	586416.GZ22_10770	2.198e-19	98.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
SRR25158535_k127_1276498_3	463191.SSEG_08299	3.132e-21	103.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158535_k127_1276498_0	2074.JNYD01000003_gene3704	3.799e-51	191.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158535_k127_1276498_5	1120947.ATUX01000006_gene511	8.711e-09	59.0	2ASDQ@1|root,31HT6@2|Bacteria,2HMBW@201174|Actinobacteria,4D6R3@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1278213_1	1121877.JQKF01000112_gene1255	9.813e-51	183.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1278213_0	1229780.BN381_250012	1.85e-158	518.0	COG3464@1|root,COG3464@2|Bacteria,2I56J@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1278213_2	105425.BBPL01000015_gene2679	4.168e-29	120.0	28N8D@1|root,2ZBCT@2|Bacteria,2GP6B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1278645_0	909663.KI867150_gene946	4.827e-118	391.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2MQXS@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SRR25158535_k127_1279895_1	1246445.ANAY01000084_gene2125	1.958e-12	66.0	COG3039@1|root,COG3039@2|Bacteria,2GJQM@201174|Actinobacteria	201174|Actinobacteria	L	Cluster 0025 8 SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_1279895_0	345341.KUTG_04850	8.939e-79	285.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
SRR25158535_k127_1279895_2	709991.Odosp_0549	1.283e-10	66.0	COG1983@1|root,COG1983@2|Bacteria,4PKK1@976|Bacteroidetes,2G0Z0@200643|Bacteroidia,231H8@171551|Porphyromonadaceae	976|Bacteroidetes	KT	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
SRR25158535_k127_1279985_5	1283283.ATXA01000003_gene1592	3.03e-14	83.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria	201174|Actinobacteria	O	organic hydroperoxide resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158535_k127_1279985_7	1122939.ATUD01000004_gene3690	9.813e-07	58.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CRPW@84995|Rubrobacteria	84995|Rubrobacteria	P	Mg2 transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158535_k127_1279985_6	1957.JODX01000024_gene4001	7.819e-10	62.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158535_k127_1279985_0	1038860.AXAP01000001_gene6347	1.079e-297	949.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,2U1CG@28211|Alphaproteobacteria,3JWWP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SRR25158535_k127_1279985_4	1137268.AZXF01000009_gene3907	1.177e-41	168.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4EII2@85012|Streptosporangiales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158535_k127_1279985_8	67257.JODR01000021_gene5064	0.0001496	44.0	COG4425@1|root,COG4425@2|Bacteria,2GKB5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158535_k127_1279985_2	1440053.JOEI01000020_gene861	2.657e-82	283.0	COG0174@1|root,COG0174@2|Bacteria,2IFHQ@201174|Actinobacteria	201174|Actinobacteria	E	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158535_k127_1279985_1	35754.JNYJ01000015_gene8440	1.026e-130	440.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D987@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1279985_3	1246995.AFR_30300	2.214e-69	249.0	COG1277@1|root,COG1277@2|Bacteria,2GMJD@201174|Actinobacteria,4DINR@85008|Micromonosporales	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158535_k127_1283692_1	42256.RradSPS_2485	1.428e-232	731.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria,4CRNM@84995|Rubrobacteria	84995|Rubrobacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
SRR25158535_k127_1283692_0	266117.Rxyl_2410	4.969e-284	905.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4CPCB@84995|Rubrobacteria	84995|Rubrobacteria	EQ	Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SRR25158535_k127_1283692_3	1120950.KB892762_gene5490	2.195e-58	226.0	COG0491@1|root,COG0491@2|Bacteria,2GKP9@201174|Actinobacteria,4DNHG@85009|Propionibacteriales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	pksB_1	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_1283692_4	1894.JOER01000078_gene7136	4.853e-47	183.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria	201174|Actinobacteria	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_1283692_2	1521187.JPIM01000120_gene293	1.194e-101	347.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi,376BM@32061|Chloroflexia	32061|Chloroflexia	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
SRR25158535_k127_1285043_0	369723.Strop_0230	1.774e-280	880.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DBBY@85008|Micromonosporales	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158535_k127_1287540_3	67332.FM21_13525	1.947e-121	413.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
SRR25158535_k127_1287540_12	253839.SSNG_02627	7.76e-06	55.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1287540_8	1463901.JOIY01000066_gene3752	1.262e-41	166.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria	201174|Actinobacteria	NU	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,zf-B_box
SRR25158535_k127_1287540_2	525909.Afer_1427	6.226e-149	490.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1287540_5	1214101.BN159_0146	1.462e-77	264.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria	201174|Actinobacteria	L	resolvase	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
SRR25158535_k127_1287540_10	370438.PTH_2772	2.219e-25	120.0	COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,24GPH@186801|Clostridia,260YH@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158535_k127_1287540_7	1380390.JIAT01000003_gene5451	1.815e-58	205.0	COG0229@1|root,COG0229@2|Bacteria,2IHV0@201174|Actinobacteria,4CQBG@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
SRR25158535_k127_1287540_4	1206730.BAGA01000077_gene1004	5.939e-117	390.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4FUGA@85025|Nocardiaceae	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158535_k127_1287540_11	1297865.APJD01000019_gene3123	5.19e-15	87.0	COG1051@1|root,COG1051@2|Bacteria,1RH1H@1224|Proteobacteria,2U6J2@28211|Alphaproteobacteria,3JYB7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_1287540_6	1123023.JIAI01000021_gene2347	1.912e-74	266.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158535_k127_1287540_0	298653.Franean1_7278	2.635e-227	741.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_1287540_1	105422.BBPM01000010_gene6689	1.097e-190	612.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,2NHP7@228398|Streptacidiphilus	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
SRR25158535_k127_1287540_9	1500257.JQNM01000002_gene4244	6.533e-37	145.0	COG1846@1|root,COG1846@2|Bacteria,1MZXE@1224|Proteobacteria,2UK9X@28211|Alphaproteobacteria,4BFYK@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158535_k127_1289383_1	644966.Tmar_2008	9.085e-203	640.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SRR25158535_k127_1289383_2	309801.trd_1336	1.947e-63	237.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158535_k127_1289383_0	644283.Micau_0494	7.708e-231	744.0	COG1061@1|root,COG1061@2|Bacteria,2GIR9@201174|Actinobacteria,4D9I6@85008|Micromonosporales	201174|Actinobacteria	L	ERCC3/RAD25/XPB C-terminal helicase	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
SRR25158535_k127_1289383_3	909613.UO65_5977	2.172e-38	157.0	COG2378@1|root,COG2378@2|Bacteria,2GURQ@201174|Actinobacteria,4DYGK@85010|Pseudonocardiales	201174|Actinobacteria	K	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
SRR25158535_k127_1290347_8	1121272.KB903290_gene4662	2.293e-06	52.0	COG3324@1|root,COG3324@2|Bacteria,2HUGB@201174|Actinobacteria,4DGBT@85008|Micromonosporales	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1290347_7	404589.Anae109_1576	8.223e-11	66.0	2FCGD@1|root,344JU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1290347_3	258052.JNYV01000016_gene3334	3.629e-28	121.0	COG2350@1|root,COG2350@2|Bacteria,2GT8J@201174|Actinobacteria	201174|Actinobacteria	S	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_1290347_2	28444.JODQ01000013_gene2896	9.341e-59	209.0	COG1595@1|root,COG1595@2|Bacteria,2GP81@201174|Actinobacteria,4EJGD@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158535_k127_1290347_1	1283283.ATXA01000021_gene2872	5.502e-71	251.0	COG0412@1|root,COG0412@2|Bacteria,2HTVD@201174|Actinobacteria,4EUUV@85013|Frankiales	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158535_k127_1290347_0	479432.Sros_4136	1.294e-146	469.0	COG0596@1|root,COG0596@2|Bacteria,2I9PQ@201174|Actinobacteria,4EHNW@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158535_k127_1290347_5	1122611.KB903964_gene4951	1.696e-23	107.0	COG2227@1|root,COG2227@2|Bacteria,2H5TR@201174|Actinobacteria,4EK1M@85012|Streptosporangiales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158535_k127_1290347_6	67373.JOBF01000013_gene4272	4.022e-12	77.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158535_k127_1291711_4	1003195.SCAT_1231	1.627e-66	239.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0008150,GO:0040007	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR25158535_k127_1291711_6	1169154.KB897783_gene4572	1.404e-10	74.0	COG2104@1|root,COG2104@2|Bacteria,2GQKM@201174|Actinobacteria	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158535_k127_1291711_3	105425.BBPL01000031_gene4401	5.122e-129	424.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria,2NFQW@228398|Streptacidiphilus	201174|Actinobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158535_k127_1291711_2	1121946.AUAX01000001_gene2347	5.984e-139	457.0	COG3693@1|root,COG3693@2|Bacteria,2I9V3@201174|Actinobacteria,4DBKC@85008|Micromonosporales	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
SRR25158535_k127_1291711_1	644282.Deba_1381	5.433e-156	502.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158535_k127_1291711_0	285535.JOEY01000002_gene4910	4.275e-243	764.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158535_k127_1291711_5	298654.FraEuI1c_6165	9.655e-27	109.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4ET07@85013|Frankiales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158535_k127_129499_3	675635.Psed_0507	1.026e-17	91.0	COG1309@1|root,COG1309@2|Bacteria,2GP59@201174|Actinobacteria,4E72V@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Transcription regulator, TetR-like, DNA-binding, bacterial archaeal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158535_k127_129499_0	67281.JNZZ01000006_gene5280	1.832e-135	439.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,419H7@629295|Streptomyces griseus group	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_129499_1	1120950.KB892707_gene4878	3.83e-79	283.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4DNDP@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158535_k127_129499_2	2002.JOEQ01000006_gene1323	5.896e-63	244.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4EGNK@85012|Streptosporangiales	201174|Actinobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
SRR25158535_k127_1296351_1	1394178.AWOO02000028_gene5397	0.0001053	53.0	2AN8M@1|root,31D6P@2|Bacteria,2I9F7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1296351_0	1394178.AWOO02000055_gene827	6.594e-27	118.0	292KZ@1|root,2ZQ4W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1296889_0	477641.MODMU_4202	8.013e-78	276.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4EVFM@85013|Frankiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_1296889_1	1120949.KB903317_gene1878	1.532e-75	259.0	COG0596@1|root,COG0596@2|Bacteria,2IFCI@201174|Actinobacteria,4DC31@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158535_k127_1296973_0	749927.AMED_1359	3.16e-77	269.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4DZ5H@85010|Pseudonocardiales	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158535_k127_1296973_2	1352941.M877_13295	2.622e-47	192.0	COG0778@1|root,COG0778@2|Bacteria,2I97S@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_1296973_1	298653.Franean1_7278	1.053e-47	177.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_1306638_2	1123024.AUII01000006_gene4636	1.564e-11	65.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4EE9U@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158535_k127_1306638_1	1380354.JIAN01000005_gene2039	4.096e-47	177.0	COG0428@1|root,COG0428@2|Bacteria,2GISJ@201174|Actinobacteria	201174|Actinobacteria	P	zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
SRR25158535_k127_1306638_0	512565.AMIS_30570	1.333e-84	285.0	COG1280@1|root,COG1280@2|Bacteria,2HRC6@201174|Actinobacteria,4DFC4@85008|Micromonosporales	201174|Actinobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
SRR25158535_k127_1306646_1	1089551.KE386572_gene1526	1.589e-22	99.0	COG0434@1|root,COG0434@2|Bacteria,1Q83B@1224|Proteobacteria,2U2I9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIM-barrel enzyme	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
SRR25158535_k127_1306646_0	1463895.JODA01000022_gene7683	2.31e-215	693.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158535_k127_1311754_9	994479.GL877883_gene7562	1.71e-05	48.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4E4AJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised P-loop hydrolase UPF0079	tsaE	GO:0008150,GO:0040007	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158535_k127_1311754_0	1463855.JOHV01000010_gene5531	6.036e-126	424.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_1311754_4	709986.Deima_1063	2.943e-31	137.0	COG4328@1|root,COG4328@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,RelA_SpoT
SRR25158535_k127_1311754_6	56110.Oscil6304_1179	3.88e-24	116.0	COG1669@1|root,COG1669@2|Bacteria,1G8GD@1117|Cyanobacteria,1HCDB@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
SRR25158535_k127_1311754_5	262724.TT_C1284	8.084e-29	128.0	COG2361@1|root,COG2361@2|Bacteria,1WKGB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SRR25158535_k127_1311754_2	1313172.YM304_08940	2.248e-48	184.0	COG1214@1|root,COG1214@2|Bacteria	2|Bacteria	O	tRNA threonylcarbamoyladenosine modification	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158535_k127_1311754_3	1229780.BN381_130035	7.254e-39	153.0	COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,3UWXZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	FR47-like protein	rimI	GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SRR25158535_k127_1311754_1	1121472.AQWN01000004_gene804	9.974e-100	344.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,260QV@186807|Peptococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SRR25158535_k127_1311754_7	326424.FRAAL4827	3.867e-15	88.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1311754_8	1074488.AGBX01000003_gene134	1.036e-14	75.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4FCXX@85020|Dermabacteraceae	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SRR25158535_k127_1313644_2	287986.DV20_00880	1.324e-99	339.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,4E0N5@85010|Pseudonocardiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1313644_3	1268303.RHODMAR_1594	2.595e-63	231.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2092,DUF4292,MucB_RseB
SRR25158535_k127_1313644_4	1121926.AXWO01000020_gene2035	2.161e-46	179.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4EYET@85014|Glycomycetales	201174|Actinobacteria	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
SRR25158535_k127_1313644_0	469371.Tbis_1182	3.536e-203	641.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4DXGM@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158535_k127_1313644_1	68570.DC74_5089	4.823e-114	379.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_1313644_5	28444.JODQ01000015_gene1826	3.315e-09	61.0	COG1432@1|root,COG1432@2|Bacteria,2GVRE@201174|Actinobacteria	201174|Actinobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
SRR25158535_k127_1313722_6	266117.Rxyl_1173	9.489e-39	150.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
SRR25158535_k127_1313722_1	1048339.KB913029_gene4290	6.326e-145	482.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4ETUQ@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158535_k127_1313722_4	1313172.YM304_15190	7.607e-97	327.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
SRR25158535_k127_1313722_3	266117.Rxyl_1174	8.663e-101	364.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
SRR25158535_k127_1313722_2	1048339.KB913029_gene4283	2.153e-117	394.0	2DNJB@1|root,32XT8@2|Bacteria,2H1A6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1313722_9	644966.Tmar_0494	1.883e-19	96.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
SRR25158535_k127_1313722_8	552811.Dehly_0222	1.077e-22	114.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi,34CWQ@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
SRR25158535_k127_1313722_5	1146883.BLASA_2344	1.004e-57	225.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4ESC2@85013|Frankiales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SRR25158535_k127_1313722_7	1123023.JIAI01000009_gene961	1.221e-23	118.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4E3CY@85010|Pseudonocardiales	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SRR25158535_k127_1313722_0	1463903.JOIZ01000019_gene6834	7.115e-265	842.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SRR25158535_k127_132296_0	1429046.RR21198_5341	8.342e-54	192.0	COG2210@1|root,COG2210@2|Bacteria,2HGHZ@201174|Actinobacteria,4FXJI@85025|Nocardiaceae	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
SRR25158535_k127_132296_1	55952.BU52_07685	9.552e-41	156.0	COG1765@1|root,COG1765@2|Bacteria,2IFY4@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158535_k127_132296_3	930171.Asphe3_21050	2.296e-10	68.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158535_k127_132296_2	68170.KL590523_gene3397	2.366e-29	120.0	2EG8Z@1|root,332XF@2|Bacteria,2GTHG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_132296_4	861299.J421_5832	3.42e-06	54.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1323480_8	1382356.JQMP01000003_gene1523	1.901e-14	83.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi,27YTI@189775|Thermomicrobia	189775|Thermomicrobia	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SRR25158535_k127_1323480_2	28444.JODQ01000001_gene2333	2.959e-117	389.0	COG0320@1|root,COG0320@2|Bacteria,2GKD4@201174|Actinobacteria,4EHZS@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
SRR25158535_k127_1323480_4	1380393.JHVP01000003_gene1087	4.744e-50	202.0	COG0321@1|root,COG0321@2|Bacteria,2GJIX@201174|Actinobacteria,4ES92@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
SRR25158535_k127_1323480_1	33876.JNXY01000018_gene7749	7.246e-134	442.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4D8FV@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158535_k127_1323480_5	43354.JOIJ01000025_gene3237	4.07e-44	182.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4E9JX@85010|Pseudonocardiales	201174|Actinobacteria	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1323480_0	457429.ABJI02000146_gene7057	1.98e-163	527.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_1323480_7	653045.Strvi_1527	7.053e-24	110.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158535_k127_1323480_6	471852.Tcur_1570	2.032e-38	152.0	2E6TR@1|root,331DK@2|Bacteria,2IQF8@201174|Actinobacteria,4EJJZ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1323480_3	526226.Gbro_3071	4.185e-52	192.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4GA48@85026|Gordoniaceae	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158535_k127_1330539_0	1476876.JOJO01000003_gene5523	1.966e-143	463.0	COG0025@1|root,COG0025@2|Bacteria,2I9RZ@201174|Actinobacteria	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
SRR25158535_k127_1330539_2	66874.JOFS01000061_gene5666	2.224e-11	76.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158535_k127_1330539_1	2074.JNYD01000021_gene865	5.756e-74	254.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria,4EAS4@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1346455_0	471852.Tcur_1701	0.0	1090.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158535_k127_1346455_2	84531.JMTZ01000040_gene607	1.839e-29	124.0	COG3296@1|root,COG3296@2|Bacteria,1N8TC@1224|Proteobacteria,1SEZY@1236|Gammaproteobacteria,1X76D@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
SRR25158535_k127_1346455_1	469371.Tbis_2474	7.161e-47	179.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4DXKT@85010|Pseudonocardiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SRR25158535_k127_1348011_0	1120950.KB892759_gene6283	4.206e-93	315.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4DPEA@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	cofD	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
SRR25158535_k127_1348011_1	1160137.KB907308_gene6456	1.195e-70	256.0	COG0778@1|root,COG1478@1|root,COG0778@2|Bacteria,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4FXW9@85025|Nocardiaceae	201174|Actinobacteria	C	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
SRR25158535_k127_1362837_1	1246995.AFR_07015	1.082e-50	185.0	COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4DBDZ@85008|Micromonosporales	201174|Actinobacteria	GK	ROK family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,MarR_2,ROK
SRR25158535_k127_1362837_0	1385518.N798_16405	1.319e-110	368.0	COG0664@1|root,COG0664@2|Bacteria,2ID3H@201174|Actinobacteria	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158535_k127_1362837_3	1894.JOER01000025_gene6933	9.792e-14	83.0	COG5592@1|root,COG5592@2|Bacteria,2IGW0@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SRR25158535_k127_1362837_2	685727.REQ_44950	1.326e-15	81.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4G36P@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158535_k127_139241_4	526225.Gobs_2753	3.125e-15	82.0	COG3293@1|root,COG3293@2|Bacteria,2IIAY@201174|Actinobacteria,4EVQX@85013|Frankiales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR25158535_k127_139241_3	1435356.Y013_25970	1.534e-22	107.0	COG3293@1|root,COG3293@2|Bacteria,2IIAY@201174|Actinobacteria,4G1V8@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR25158535_k127_139241_0	1394178.AWOO02000015_gene7012	1.634e-66	241.0	COG0640@1|root,COG0640@2|Bacteria,2GTPG@201174|Actinobacteria,4EIP7@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158535_k127_139241_1	479432.Sros_6153	2.639e-47	189.0	2DN70@1|root,32VWP@2|Bacteria,2IGZC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_139241_2	1254432.SCE1572_01045	3.739e-32	130.0	COG1222@1|root,COG1222@2|Bacteria,1R4U1@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,ClpS
SRR25158535_k127_139401_0	502025.Hoch_4147	2.632e-257	812.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
SRR25158535_k127_139401_1	1210045.ALNP01000012_gene1530	3.202e-152	492.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria	201174|Actinobacteria	F	Dihydropyrimidinase	hyuA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158535_k127_140440_0	35754.JNYJ01000050_gene7957	8.209e-89	295.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria,4DAEY@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158535_k127_140440_2	1128421.JAGA01000002_gene1044	1.292e-45	173.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_140440_1	1123023.JIAI01000016_gene3468	8.161e-65	239.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IH0Y@201174|Actinobacteria,4E30J@85010|Pseudonocardiales	201174|Actinobacteria	FL	Metal binding domain of Ada	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1
SRR25158535_k127_140440_3	67373.JOBF01000013_gene4373	3.795e-19	88.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_1409063_1	1121926.AXWO01000007_gene140	6.024e-44	178.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria,4EYBW@85014|Glycomycetales	201174|Actinobacteria	L	HELICc2	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
SRR25158535_k127_1409063_3	313589.JNB_10089	1.188e-17	83.0	2E3JZ@1|root,32YI8@2|Bacteria,2GQIX@201174|Actinobacteria,4FHQA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
SRR25158535_k127_1409063_2	1229780.BN381_100117	1.592e-22	102.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,3UWYX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158535_k127_1409063_0	443143.GM18_2380	1.712e-71	252.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,43S6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158535_k127_1412988_0	1382306.JNIM01000001_gene3284	0.0	1408.0	COG3387@1|root,COG4945@1|root,COG3387@2|Bacteria,COG4945@2|Bacteria,2G69A@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase 15-related	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_C,Glucodextran_N,Glyco_hydro_15
SRR25158535_k127_1412988_1	526225.Gobs_1475	1.343e-82	291.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4EVRM@85013|Frankiales	201174|Actinobacteria	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158535_k127_1412988_4	1223523.H340_20886	2.754e-29	136.0	COG2197@1|root,COG2197@2|Bacteria,2GNAU@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_1412988_2	869210.Marky_0355	1.054e-35	152.0	COG4585@1|root,COG4585@2|Bacteria,1WJNH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
SRR25158535_k127_1412988_3	649831.L083_0676	1.127e-31	139.0	COG2199@1|root,COG3706@2|Bacteria,2ID0G@201174|Actinobacteria,4DBK9@85008|Micromonosporales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SRR25158535_k127_1420049_3	378806.STAUR_1477	2.037e-26	114.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YWK2@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
SRR25158535_k127_1420049_6	977880.pRALTA_0086	4.674e-06	53.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VNU5@28216|Betaproteobacteria,1K1AA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
SRR25158535_k127_1420049_4	1463887.KL590055_gene6452	4.935e-09	59.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158535_k127_1420049_1	1121406.JAEX01000007_gene2379	7.395e-125	412.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2MGAK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
SRR25158535_k127_1420049_0	298654.FraEuI1c_5768	1.018e-185	608.0	COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4ERWF@85013|Frankiales	201174|Actinobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SRR25158535_k127_1420049_2	365528.KB891268_gene6002	8.9e-79	273.0	COG2203@1|root,COG2801@1|root,COG2203@2|Bacteria,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SRR25158535_k127_1423314_0	1380390.JIAT01000009_gene1482	5.291e-109	373.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CRYH@84995|Rubrobacteria	84995|Rubrobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158535_k127_1423314_1	1120934.KB894435_gene4459	1.756e-05	47.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4DXEE@85010|Pseudonocardiales	201174|Actinobacteria	CH	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8,Oxidored_FMN
SRR25158535_k127_1425768_3	1123065.ATWL01000015_gene2609	8.579e-15	85.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_1425768_0	591158.SSMG_01157	1.614e-146	470.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_1425768_2	1382306.JNIM01000001_gene3667	1.525e-15	86.0	COG0671@1|root,COG0671@2|Bacteria,2G7F8@200795|Chloroflexi	200795|Chloroflexi	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158535_k127_1425768_1	1144275.COCOR_07304	4.62e-23	109.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,42RSB@68525|delta/epsilon subdivisions,2WNIX@28221|Deltaproteobacteria,2YYCE@29|Myxococcales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158535_k127_1430890_3	479432.Sros_6786	4.161e-105	355.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EI8B@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
SRR25158535_k127_1430890_6	1121403.AUCV01000033_gene3639	2.278e-07	55.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2MJGM@213118|Desulfobacterales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
SRR25158535_k127_1430890_2	591167.Sfla_1907	8.982e-137	451.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
SRR25158535_k127_1430890_0	1003195.SCAT_1838	8.032e-320	1000.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SRR25158535_k127_1430890_5	1120949.KB903307_gene1388	2.949e-38	148.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4DCAH@85008|Micromonosporales	201174|Actinobacteria	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158535_k127_1430890_4	1120949.KB903357_gene4748	1.195e-38	148.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158535_k127_1430890_1	1120950.KB892744_gene2728	4.468e-179	574.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4DV7H@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF4118,GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PAS_4,PAS_9,Response_reg
SRR25158535_k127_1432879_0	356851.JOAN01000016_gene6169	8.951e-104	359.0	COG3693@1|root,COG3693@2|Bacteria,2I9V3@201174|Actinobacteria,4DBKC@85008|Micromonosporales	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
SRR25158535_k127_1433729_0	1306174.JODP01000009_gene6552	1.29e-06	61.0	2DS3G@1|root,33ECD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TbpB_B_D,Transglut_core
SRR25158535_k127_1436198_3	1089545.KB913037_gene5783	4.254e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria,4E70D@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158535_k127_1436198_13	253839.SSNG_00629	4.152e-09	58.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria	201174|Actinobacteria	M	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158535_k127_1436198_2	1449976.KALB_8782	1.919e-114	376.0	COG0702@1|root,COG0702@2|Bacteria,2GJB8@201174|Actinobacteria,4E26P@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SRR25158535_k127_1436198_4	1370121.AUWS01000014_gene7180	2.728e-95	331.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,2387Z@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1436198_12	909613.UO65_4134	1.426e-20	98.0	COG1828@1|root,COG1828@2|Bacteria,2GQV4@201174|Actinobacteria,4E5FK@85010|Pseudonocardiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
SRR25158535_k127_1436198_7	1123024.AUII01000015_gene3762	3.048e-66	247.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria,4DY2B@85010|Pseudonocardiales	201174|Actinobacteria	V	Beta-lactamase class C	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158535_k127_1436198_6	298653.Franean1_0158	2.58e-81	288.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4ERSR@85013|Frankiales	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
SRR25158535_k127_1436198_0	1444309.JAQG01000019_gene519	1.685e-219	709.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,26RX8@186822|Paenibacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158535_k127_1436198_8	1460634.JCM19037_3596	1.844e-63	237.0	COG5276@1|root,COG5276@2|Bacteria,1UUVN@1239|Firmicutes,4HBJX@91061|Bacilli	91061|Bacilli	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
SRR25158535_k127_1436198_5	479433.Caci_7865	1.126e-81	277.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR25158535_k127_1436198_11	106370.Francci3_2858	9.527e-33	130.0	COG1846@1|root,COG1846@2|Bacteria,2GQV6@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR25158535_k127_1436198_10	656024.FsymDg_3902	3.288e-58	205.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria	201174|Actinobacteria	S	Roadblock lc7 family protein	cvnB6	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR25158535_k127_1436198_1	326424.FRAAL4397	1.969e-137	471.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158535_k127_1436198_9	369723.Strop_0154	2.25e-59	213.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DB2D@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158535_k127_1441070_0	1463920.JOGB01000063_gene4204	2.021e-125	411.0	COG0477@1|root,COG2814@2|Bacteria,2HRV9@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1441070_2	1121957.ATVL01000007_gene2166	6.282e-74	254.0	COG0668@1|root,COG0668@2|Bacteria,4NFX6@976|Bacteroidetes,47K5W@768503|Cytophagia	976|Bacteroidetes	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158535_k127_1441070_7	371042.NG99_12240	6.921e-05	56.0	COG0668@1|root,COG0668@2|Bacteria,1MW7V@1224|Proteobacteria,1RYVT@1236|Gammaproteobacteria,3X71H@551|Erwinia	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
SRR25158535_k127_1441070_1	235985.BBPN01000001_gene1081	3.631e-107	356.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NFPR@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158535_k127_1441070_3	981369.JQMJ01000004_gene5276	6.265e-68	239.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,2NJ3P@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_1441070_5	511051.CSE_10910	1.26e-38	153.0	COG2316@1|root,COG2316@2|Bacteria	2|Bacteria	J	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
SRR25158535_k127_1441070_6	644283.Micau_1142	1.534e-35	139.0	COG0662@1|root,COG0662@2|Bacteria,2II1B@201174|Actinobacteria,4DDJ1@85008|Micromonosporales	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1441070_4	867903.ThesuDRAFT_01914	6.16e-55	199.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1448628_8	1463854.JOHT01000036_gene3442	1.217e-05	53.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
SRR25158535_k127_1448628_6	103733.JNYO01000011_gene4878	1.007e-21	106.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria,4E186@85010|Pseudonocardiales	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
SRR25158535_k127_1448628_0	443255.SCLAV_2102	1.286e-102	342.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	mtrA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1448628_2	994479.GL877883_gene7244	3.368e-75	272.0	COG5002@1|root,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria,4E174@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	mtrB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.7.13.3	ko:K07636,ko:K07654	ko02020,map02020	M00434,M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_1448628_9	863365.XHC_3015	6.939e-05	56.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,1X4FD@135614|Xanthomonadales	135614|Xanthomonadales	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
SRR25158535_k127_1448628_5	357808.RoseRS_1234	1.919e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_1448628_4	477641.MODMU_2340	1.989e-27	127.0	COG5662@1|root,COG5662@2|Bacteria,2GN1B@201174|Actinobacteria,4ERKE@85013|Frankiales	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1448628_1	479434.Sthe_2191	2.103e-99	334.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1448628_3	479434.Sthe_2192	3.852e-49	196.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi,27Y36@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158535_k127_1448628_10	253839.SSNG_02746	0.0006618	52.0	COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria	201174|Actinobacteria	S	phosphoribosyltransferase	pyrE_1	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158535_k127_1448628_7	298655.KI912266_gene121	2.971e-16	93.0	COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4ESQU@85013|Frankiales	201174|Actinobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SRR25158535_k127_1461383_6	298655.KI912266_gene1197	5.368e-51	186.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4ET85@85013|Frankiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	potH	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
SRR25158535_k127_1461383_2	298655.KI912266_gene1196	7.347e-137	454.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,4ESHI@85013|Frankiales	201174|Actinobacteria	E	PFAM extracellular solute-binding protein family 1	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
SRR25158535_k127_1461383_0	471852.Tcur_3396	2.245e-145	471.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EFFE@85012|Streptosporangiales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
SRR25158535_k127_1461383_9	1304880.JAGB01000002_gene1948	1.067e-13	84.0	COG0675@1|root,COG0675@2|Bacteria,1UZNC@1239|Firmicutes,24FN6@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1461383_7	1120949.KB903307_gene1465	1.167e-48	192.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1461383_3	469383.Cwoe_1333	1.278e-85	305.0	COG2508@1|root,COG2508@2|Bacteria,2GNDH@201174|Actinobacteria,4CRKT@84995|Rubrobacteria	84995|Rubrobacteria	QT	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
SRR25158535_k127_1461383_5	395961.Cyan7425_1835	1.001e-65	242.0	COG1748@1|root,COG1748@2|Bacteria,1G37A@1117|Cyanobacteria	1117|Cyanobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
SRR25158535_k127_1461383_1	1121472.AQWN01000011_gene1218	6.003e-144	484.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia,2611N@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iHN637.CLJU_RS10045	Aminotran_3
SRR25158535_k127_1461383_8	635013.TherJR_2042	2.29e-37	149.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SRR25158535_k127_1461383_4	232721.Ajs_2804	7.599e-77	278.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2VHJU@28216|Betaproteobacteria,4AB94@80864|Comamonadaceae	28216|Betaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158535_k127_1462066_1	1246995.AFR_21970	3.621e-47	178.0	COG0789@1|root,COG0789@2|Bacteria,2IQMK@201174|Actinobacteria,4DFHG@85008|Micromonosporales	201174|Actinobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158535_k127_1462066_0	298655.KI912266_gene6026	1.949e-226	739.0	COG2304@1|root,COG2304@2|Bacteria,2I3I0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Vault protein inter-alpha-trypsin domain protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SRR25158535_k127_1462066_2	365528.KB891234_gene121	1.924e-32	128.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4ERKH@85013|Frankiales	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158535_k127_1467593_1	429009.Adeg_1664	1.019e-22	100.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,42H84@68295|Thermoanaerobacterales	186801|Clostridia	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SRR25158535_k127_1467593_2	1035308.AQYY01000001_gene3157	9.11e-06	57.0	COG0481@1|root,COG0532@1|root,COG0481@2|Bacteria,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158535_k127_1467593_0	309801.trd_0773	9.512e-36	144.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi,27XWF@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158535_k127_14772_11	1136417.AZWE01000103_gene2828	2.708e-40	153.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria,4DD18@85008|Micromonosporales	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
SRR25158535_k127_14772_12	1463887.KL590086_gene2477	2.637e-32	132.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
SRR25158535_k127_14772_10	1229780.BN381_420033	4.704e-42	162.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Ferric_reduct,NAD_binding_1
SRR25158535_k127_14772_6	68219.JNXI01000010_gene5736	4.261e-61	222.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
SRR25158535_k127_14772_7	390989.JOEG01000003_gene4686	7.934e-55	205.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4D9TH@85008|Micromonosporales	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_14772_8	356851.JOAN01000017_gene5898	9.989e-46	167.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4D9TH@85008|Micromonosporales	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_14772_2	1394178.AWOO02000009_gene4435	1.471e-151	496.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4EHHW@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_14772_5	469371.Tbis_1904	4.338e-64	231.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DXXX@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_14772_13	1380347.JNII01000011_gene838	1.829e-28	123.0	2FDZX@1|root,34604@2|Bacteria,2IN56@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_14772_3	479432.Sros_3707	5.125e-103	356.0	COG1226@1|root,COG1226@2|Bacteria,2I8YK@201174|Actinobacteria,4EPYX@85012|Streptosporangiales	201174|Actinobacteria	P	RyR domain	-	-	-	-	-	-	-	-	-	-	-	-	RyR,TrkA_N
SRR25158535_k127_14772_1	222534.KB893698_gene6074	4.711e-152	497.0	COG4467@1|root,COG4467@2|Bacteria,2IDK7@201174|Actinobacteria	201174|Actinobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR25158535_k127_14772_9	1463879.JOHP01000004_gene6498	1.3e-44	175.0	COG1607@1|root,COG1607@2|Bacteria,2GK6X@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA hydrolase	-	-	3.1.2.23	ko:K01075,ko:K10806	ko00130,ko00362,ko01040,ko01100,ko01110,ko01120,map00130,map00362,map01040,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
SRR25158535_k127_14772_15	1128421.JAGA01000001_gene2336	0.0002976	54.0	2DDA6@1|root,2ZH98@2|Bacteria	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT
SRR25158535_k127_14772_4	864702.OsccyDRAFT_1593	9.417e-82	283.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_14772_0	1122138.AQUZ01000049_gene2367	1.102e-248	774.0	COG0520@1|root,COG0520@2|Bacteria,2GP7W@201174|Actinobacteria,4DNX7@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158535_k127_1478049_5	264732.Moth_0912	1.434e-39	158.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_1478049_2	1121468.AUBR01000005_gene40	5.35e-85	308.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_1478049_3	321332.CYB_2417	1.25e-73	252.0	COG0512@1|root,COG0512@2|Bacteria,1G0QK@1117|Cyanobacteria,1GZ8F@1129|Synechococcus	1117|Cyanobacteria	EH	Anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SRR25158535_k127_1478049_0	333138.LQ50_06395	1.173e-183	603.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1478049_4	28444.JODQ01000009_gene3719	3.168e-41	160.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4EIK2@85012|Streptosporangiales	201174|Actinobacteria	M	Sortase family	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
SRR25158535_k127_1478049_7	309801.trd_A0739	8.737e-23	107.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158535_k127_1478049_8	1122611.KB903952_gene5830	1.478e-08	63.0	2E4NY@1|root,32ZHR@2|Bacteria,2HZN4@201174|Actinobacteria,4EKK3@85012|Streptosporangiales	201174|Actinobacteria	D	Involved in cell division	crgA	-	-	-	-	-	-	-	-	-	-	-	CrgA
SRR25158535_k127_1478049_9	243365.CV_3742	0.0001641	53.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,2KS07@206351|Neisseriales	206351|Neisseriales	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158535_k127_1478049_1	485913.Krac_8294	1.282e-149	482.0	COG0183@1|root,COG0183@2|Bacteria,2G80D@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_1478049_6	234267.Acid_4828	1.316e-36	139.0	COG0652@1|root,COG0652@2|Bacteria,3Y4CX@57723|Acidobacteria	57723|Acidobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SRR25158535_k127_1479368_0	1313172.YM304_09040	2.277e-113	372.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158535_k127_1479368_3	561175.KB894103_gene1249	1.105e-40	164.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4EI5T@85012|Streptosporangiales	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SRR25158535_k127_1479368_2	66897.DJ64_10910	1.4e-49	195.0	COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria	201174|Actinobacteria	H	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158535_k127_1479368_1	1120950.KB892749_gene3350	8.375e-53	194.0	COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4DQV0@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SRR25158535_k127_1481951_0	345341.KUTG_09925	1.388e-162	524.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria,4EAUY@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158535_k127_1481951_4	1449058.JQKT01000010_gene2045	2.117e-08	61.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4FKHQ@85023|Microbacteriaceae	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158535_k127_1481951_3	1033736.CAHK01000031_gene1485	2.571e-12	70.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4F95A@85019|Brevibacteriaceae	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158535_k127_1481951_2	1380370.JIBA01000014_gene2126	1.718e-40	158.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4FEWB@85021|Intrasporangiaceae	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158535_k127_1481951_1	1283283.ATXA01000010_gene4500	4.277e-103	339.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_148405_6	512565.AMIS_48330	8.66e-13	79.0	COG2382@1|root,COG2382@2|Bacteria,2HWND@201174|Actinobacteria,4DJN7@85008|Micromonosporales	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158535_k127_148405_3	246197.MXAN_3659	2.031e-26	110.0	COG3324@1|root,COG3324@2|Bacteria,1QXUH@1224|Proteobacteria	1224|Proteobacteria	S	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_148405_1	1123320.KB889561_gene4872	2.469e-81	274.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158535_k127_148405_0	2074.JNYD01000026_gene649	5.536e-141	479.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E16G@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_148405_2	2074.JNYD01000055_gene2331	5.361e-32	130.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E16G@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_148405_7	1298863.AUEP01000011_gene629	2.935e-06	51.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158535_k127_148405_4	1028801.RG1141_PA03050	6.705e-26	113.0	COG0454@1|root,COG0456@2|Bacteria,1R6DW@1224|Proteobacteria,2U3QR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158535_k127_148405_5	66373.JOFQ01000003_gene5644	4.405e-15	83.0	COG1917@1|root,COG1917@2|Bacteria,2IT36@201174|Actinobacteria	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1490714_0	566461.SSFG_07538	1.76e-175	560.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_1490714_2	710111.FraQA3DRAFT_5926	0.0002878	52.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4ETXP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
SRR25158535_k127_1490714_1	33876.JNXY01000014_gene3932	1.827e-21	96.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4DCYX@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_1517596_4	405948.SACE_4008	2.435e-93	311.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,4DX73@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158535_k127_1517596_5	405948.SACE_4007	2.139e-80	282.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DZRW@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	catJ	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158535_k127_1517596_1	1123251.ATWM01000004_gene1974	3.419e-166	546.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,4FE6A@85021|Intrasporangiaceae	201174|Actinobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
SRR25158535_k127_1517596_3	479432.Sros_3911	8.899e-119	404.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4EFIG@85012|Streptosporangiales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_1517596_6	1463856.JOHY01000004_gene6486	2.034e-49	202.0	COG1721@1|root,COG1721@2|Bacteria,2I9E2@201174|Actinobacteria	201174|Actinobacteria	S	protein some members contain a von Willebrand factor type A vWA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SRR25158535_k127_1517596_10	1123322.KB904647_gene1669	3.11e-08	67.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158535_k127_1517596_0	469383.Cwoe_2152	2.395e-206	657.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,4CSNK@84995|Rubrobacteria	84995|Rubrobacteria	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding_C_2
SRR25158535_k127_1517596_2	1394178.AWOO02000024_gene5577	5.068e-119	391.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4EG5D@85012|Streptosporangiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158535_k127_1517596_7	1380347.JNII01000007_gene234	1.466e-46	171.0	COG1695@1|root,COG1695@2|Bacteria,2IM8U@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
SRR25158535_k127_1525764_3	1079986.JH164864_gene6613	1.127e-99	329.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158535_k127_1525764_4	1463917.JODC01000007_gene7461	2.605e-89	308.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158535_k127_1525764_5	285535.JOEY01000011_gene6150	2.36e-85	292.0	COG1028@1|root,COG1028@2|Bacteria,2I6UQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158535_k127_1525764_2	1463917.JODC01000007_gene7463	1.252e-120	414.0	COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1525764_1	66874.JOFS01000008_gene2291	9.388e-232	727.0	COG0402@1|root,COG0402@2|Bacteria,2GNUN@201174|Actinobacteria	201174|Actinobacteria	F	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_1525764_0	1120950.KB892720_gene1878	4.99e-239	755.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DPKW@85009|Propionibacteriales	201174|Actinobacteria	EU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158535_k127_1525764_6	526225.Gobs_3227	1.163e-18	89.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EU51@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_1525764_7	1235798.C817_04356	9.243e-05	46.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27V6S@189330|Dorea	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_1527523_1	335543.Sfum_3753	1.926e-64	236.0	COG0826@1|root,COG0826@2|Bacteria,1N4QJ@1224|Proteobacteria,42YJR@68525|delta/epsilon subdivisions,2WUQ1@28221|Deltaproteobacteria,2MR6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
SRR25158535_k127_1527523_0	1120950.KB892707_gene4732	6.818e-266	827.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4DNMB@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2900c	Molybdopterin,Molydop_binding
SRR25158535_k127_1528386_8	1068978.AMETH_4253	1.475e-26	115.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4E8BC@85010|Pseudonocardiales	201174|Actinobacteria	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_1528386_7	1169161.KB897730_gene1173	1.7e-29	127.0	COG0251@1|root,COG0251@2|Bacteria,2II9B@201174|Actinobacteria	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SRR25158535_k127_1528386_6	1206739.BAGJ01000001_gene6188	9.763e-71	252.0	COG3554@1|root,COG3554@2|Bacteria,2HHY3@201174|Actinobacteria,4G1MK@85025|Nocardiaceae	201174|Actinobacteria	S	Putative glycolipid-binding	-	-	-	-	-	-	-	-	-	-	-	-	Glycolipid_bind
SRR25158535_k127_1528386_0	105422.BBPM01000001_gene4704	9.875e-171	571.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
SRR25158535_k127_1528386_1	105422.BBPM01000001_gene4705	1.03e-168	539.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,2NEU0@228398|Streptacidiphilus	201174|Actinobacteria	E	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_1528386_2	526225.Gobs_2762	8.134e-137	444.0	COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4ET1H@85013|Frankiales	201174|Actinobacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SRR25158535_k127_1528386_10	1032480.MLP_27490	5.253e-08	65.0	28X5C@1|root,2ZJ3T@2|Bacteria,2GVCH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1528386_5	479434.Sthe_1923	3.762e-99	349.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	DUF3500
SRR25158535_k127_1528386_4	322710.Avin_50110	6.97e-104	355.0	COG0673@1|root,COG0673@2|Bacteria,1NQ54@1224|Proteobacteria,1RZTE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_1528386_3	105422.BBPM01000001_gene4717	1.185e-112	371.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,2NKQY@228398|Streptacidiphilus	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158535_k127_1529917_5	1123320.KB889723_gene7520	8.905e-15	76.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_1529917_2	1713.JOFV01000005_gene2394	4.325e-51	201.0	COG0699@1|root,COG0699@2|Bacteria,2GM68@201174|Actinobacteria,4F0FD@85016|Cellulomonadaceae	201174|Actinobacteria	S	50S ribosome-binding GTPase	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
SRR25158535_k127_1529917_1	526225.Gobs_0079	1.058e-88	315.0	COG0699@1|root,COG0699@2|Bacteria,2GJX9@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SRR25158535_k127_1529917_4	1968.JOEV01000005_gene6301	1.292e-28	126.0	COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SRR25158535_k127_1529917_3	887062.HGR_12432	7.019e-29	136.0	COG1196@1|root,COG1196@2|Bacteria,1NGZ2@1224|Proteobacteria,2VIWY@28216|Betaproteobacteria,4AGAW@80864|Comamonadaceae	28216|Betaproteobacteria	D	SMC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_29,SMC_N
SRR25158535_k127_1529917_0	1379270.AUXF01000005_gene352	2.683e-125	409.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	4CL	-	6.2.1.12	ko:K01904	ko00130,ko00360,ko00940,ko01100,ko01110,map00130,map00360,map00940,map01100,map01110	M00039,M00137,M00350	R01616,R01943,R02194,R02221,R02255,R06583	RC00004,RC00131	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1531144_1	644283.Micau_1853	3.612e-07	60.0	2DCQM@1|root,2ZEYX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1531144_0	298654.FraEuI1c_1503	1.206e-92	312.0	COG4974@1|root,COG4974@2|Bacteria,2HTVG@201174|Actinobacteria,4EUVH@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158535_k127_1534654_2	558173.CDOO_02325	5.262e-80	271.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,22JPX@1653|Corynebacteriaceae	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1534654_1	1237149.C900_04446	7.628e-85	299.0	COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,47P5H@768503|Cytophagia	976|Bacteroidetes	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
SRR25158535_k127_1534654_0	926550.CLDAP_00830	3.7e-86	296.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158535_k127_1534654_3	309801.trd_1830	9.248e-76	276.0	COG0581@1|root,COG0581@2|Bacteria,2GBVI@200795|Chloroflexi,27YID@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
SRR25158535_k127_1534654_4	1128427.KB904821_gene776	1.643e-28	118.0	COG1117@1|root,COG1117@2|Bacteria,1G0P6@1117|Cyanobacteria,1H8Z3@1150|Oscillatoriales	1117|Cyanobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB-2	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158535_k127_1538506_1	1089552.KI911559_gene1302	4.383e-90	306.0	COG1732@1|root,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,2TTY6@28211|Alphaproteobacteria,2JT4D@204441|Rhodospirillales	204441|Rhodospirillales	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	-	-	-	-	-	-	-	-	-	OpuAC
SRR25158535_k127_1538506_3	1122139.KB907877_gene3015	3.033e-79	282.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	transport	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SRR25158535_k127_1538506_2	1089552.KI911559_gene1300	1.931e-81	294.0	COG1174@1|root,COG1174@2|Bacteria,1MXA1@1224|Proteobacteria,2TUNH@28211|Alphaproteobacteria,2JRQ5@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
SRR25158535_k127_1538506_0	1304275.C41B8_04296	1.636e-127	418.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,1RQWQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	abc transporter atp-binding protein	yehX	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
SRR25158535_k127_1538506_4	498761.HM1_1864	6.959e-66	238.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158535_k127_1539848_0	710696.Intca_3039	4.892e-16	80.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158535_k127_1539848_1	909663.KI867150_gene1149	1.301e-12	76.0	COG0664@1|root,COG0664@2|Bacteria,1NAYS@1224|Proteobacteria,42W1E@68525|delta/epsilon subdivisions,2WS96@28221|Deltaproteobacteria,2MS9T@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158535_k127_1539848_2	2074.JNYD01000002_gene5547	2.483e-12	76.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4E11A@85010|Pseudonocardiales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
SRR25158535_k127_1539848_3	883169.HMPREF9719_01634	2.074e-05	47.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,22KBB@1653|Corynebacteriaceae	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase alpha subunit	accBC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3285	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158535_k127_1542917_3	223184.AS25_06130	2.314e-05	47.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,1W98E@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158535_k127_1542917_0	926560.KE387025_gene4008	1.971e-90	308.0	COG0675@1|root,COG0675@2|Bacteria,1WIJR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1542917_2	867903.ThesuDRAFT_01019	9.013e-13	79.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1542917_1	926560.KE387025_gene4008	2.168e-16	81.0	COG0675@1|root,COG0675@2|Bacteria,1WIJR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1543598_1	1122939.ATUD01000006_gene1750	4.969e-100	333.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4CRA5@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158535_k127_1543598_2	134676.ACPL_2702	4.995e-85	291.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4DIDR@85008|Micromonosporales	201174|Actinobacteria	P	Cation efflux family	catA	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SRR25158535_k127_1543598_0	1206741.BAFX01000017_gene7137	8.012e-125	411.0	COG2346@1|root,COG3369@1|root,COG3592@1|root,COG2346@2|Bacteria,COG3369@2|Bacteria,COG3592@2|Bacteria,2GMG5@201174|Actinobacteria,4FZD3@85025|Nocardiaceae	201174|Actinobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	ABM,Bac_globin,Fer4_19,zf-CDGSH
SRR25158535_k127_1546002_0	68260.JOAY01000098_gene5413	1.738e-191	602.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR25158535_k127_1546002_1	290397.Adeh_2440	5.165e-32	131.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
SRR25158535_k127_1546299_0	369723.Strop_2135	7.96e-69	250.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158535_k127_1547481_0	446470.Snas_3339	5.666e-157	509.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_1547481_12	1463887.KL589957_gene850	5.963e-05	48.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_1547481_4	446466.Cfla_0615	5.081e-96	333.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria	201174|Actinobacteria	L	Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_1547481_10	716544.wcw_p0021	6.944e-11	66.0	2EH4M@1|root,33AWJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158535_k127_1547481_8	760568.Desku_1596	6.662e-33	130.0	COG2337@1|root,COG2337@2|Bacteria,1VBXM@1239|Firmicutes,24M9K@186801|Clostridia,262GN@186807|Peptococcaceae	186801|Clostridia	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158535_k127_1547481_1	1382306.JNIM01000001_gene221	3e-149	494.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158535_k127_1547481_2	1237500.ANBA01000006_gene2552	7.581e-125	425.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,4EHK2@85012|Streptosporangiales	201174|Actinobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SRR25158535_k127_1547481_7	266117.Rxyl_1977	3.732e-36	153.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GMJZ@201174|Actinobacteria,4CU1Q@84995|Rubrobacteria	84995|Rubrobacteria	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SRR25158535_k127_1547481_6	1089455.MOPEL_074_00240	2.769e-74	263.0	COG0181@1|root,COG0181@2|Bacteria,2GMWI@201174|Actinobacteria,4F619@85018|Dermatophilaceae	201174|Actinobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0510	Porphobil_deam,Porphobil_deamC
SRR25158535_k127_1547481_3	471852.Tcur_4440	6.93e-97	342.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4EH7H@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SRR25158535_k127_1547481_5	1123320.KB889585_gene1858	1.64e-86	292.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SRR25158535_k127_1547481_9	469383.Cwoe_2901	1.699e-11	73.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF836
SRR25158535_k127_1547481_11	926569.ANT_02430	5.215e-08	58.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1547778_2	1068978.AMETH_3071	1.429e-15	81.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4E4UE@85010|Pseudonocardiales	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158535_k127_1547778_0	479432.Sros_6513	5.959e-126	422.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,4EQ0V@85012|Streptosporangiales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Laminin_G_3
SRR25158535_k127_1547778_1	1454010.JEOE01000044_gene1541	7.305e-33	128.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	bglX	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158535_k127_1547957_0	263358.VAB18032_13945	3.142e-122	397.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4DC9X@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158535_k127_1547957_1	350058.Mvan_0781	7.879e-17	86.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria,23B9T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158535_k127_1547957_2	562973.HMPREF0059_01327	2.117e-11	73.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4D3AY@85005|Actinomycetales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158535_k127_1548164_0	710685.MycrhN_3060	1.348e-131	428.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,235RP@1762|Mycobacteriaceae	201174|Actinobacteria	L	Integrase core domain	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	rve
SRR25158535_k127_1548164_3	502347.ESCAB7627_2123	3.352e-15	81.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,rve
SRR25158535_k127_1548164_2	710696.Intca_0860	1.16e-23	108.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,4FFND@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158535_k127_1548164_1	1078020.KEK_05572	2.213e-69	250.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,235AH@1762|Mycobacteriaceae	201174|Actinobacteria	L	IstB-like ATP binding protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0022616,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901576	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158535_k127_1550471_0	298653.Franean1_6769	1.335e-38	164.0	COG0286@1|root,COG1002@1|root,COG0286@2|Bacteria,COG1002@2|Bacteria,2GNHT@201174|Actinobacteria	201174|Actinobacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1552156_1	1121924.ATWH01000004_gene2433	3.802e-185	590.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4FK8I@85023|Microbacteriaceae	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_1552156_3	67373.JOBF01000002_gene1347	4.314e-67	246.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
SRR25158535_k127_1552156_5	714083.JH370377_gene353	2.377e-25	116.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria,4FNUC@85023|Microbacteriaceae	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158535_k127_1552156_2	1123073.KB899243_gene679	5.756e-74	254.0	COG1011@1|root,COG1011@2|Bacteria,1RHAB@1224|Proteobacteria,1T2HX@1236|Gammaproteobacteria,1XD5V@135614|Xanthomonadales	135614|Xanthomonadales	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158535_k127_1552156_4	358823.DF19_10415	7.526e-42	171.0	COG3620@1|root,COG3837@1|root,COG3620@2|Bacteria,COG3837@2|Bacteria,2I4X7@201174|Actinobacteria	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SRR25158535_k127_1552156_0	351607.Acel_1043	9.079e-244	757.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,4ESAX@85013|Frankiales	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
SRR25158535_k127_1554774_0	253839.SSNG_07403	4.935e-160	520.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158535_k127_1554774_1	1464048.JNZS01000010_gene5227	3.518e-37	147.0	COG1801@1|root,COG1801@2|Bacteria,2HU1R@201174|Actinobacteria,4DADR@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158535_k127_1561157_1	1121877.JQKF01000003_gene1489	1.727e-76	261.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CMZ4@84992|Acidimicrobiia	84992|Acidimicrobiia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158535_k127_1561157_0	1033730.CAHG01000002_gene2976	1.073e-146	477.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4DP2M@85009|Propionibacteriales	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SRR25158535_k127_1563746_3	1122611.KB903952_gene6157	5.955e-40	150.0	COG0640@1|root,COG0640@2|Bacteria,2IQYC@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
SRR25158535_k127_1563746_4	1122611.KB903952_gene6156	1.17e-38	154.0	COG3832@1|root,COG3832@2|Bacteria,2II0Q@201174|Actinobacteria,4EP5G@85012|Streptosporangiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_1563746_1	479432.Sros_1026	1.653e-63	231.0	294UC@1|root,2ZS7I@2|Bacteria,2III4@201174|Actinobacteria,4EP9J@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
SRR25158535_k127_1563746_0	1125971.ASJB01000028_gene7782	6.448e-128	417.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DZWN@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_1563746_2	326424.FRAAL2568	2.333e-48	183.0	COG0596@1|root,COG0596@2|Bacteria,2GQHN@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158535_k127_1563746_5	1283300.ATXB01000001_gene2241	2.424e-09	58.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,1S5TZ@1236|Gammaproteobacteria,1XF5S@135618|Methylococcales	135618|Methylococcales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR25158535_k127_1564091_0	357808.RoseRS_2985	0.0	1370.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,37589@32061|Chloroflexia	32061|Chloroflexia	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SRR25158535_k127_1564091_1	1237500.ANBA01000013_gene3995	1.725e-107	382.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4EFFD@85012|Streptosporangiales	201174|Actinobacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SRR25158535_k127_1564091_2	1223543.GP2_012_00940	2.241e-26	116.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4GCN5@85026|Gordoniaceae	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
SRR25158535_k127_1566989_3	561175.KB894095_gene2188	1.041e-05	48.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4EN0M@85012|Streptosporangiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158535_k127_1566989_1	1206101.AZXC01000010_gene249	1.332e-150	491.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
SRR25158535_k127_1566989_2	471852.Tcur_0083	2.732e-50	184.0	COG0490@1|root,COG0490@2|Bacteria,2IFBQ@201174|Actinobacteria,4EJDK@85012|Streptosporangiales	201174|Actinobacteria	P	TrkA-C domain	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
SRR25158535_k127_1566989_0	479432.Sros_5639	9.125e-178	593.0	COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4EID4@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158535_k127_1572237_5	1064537.AGSO01000001_gene661	7.74e-37	148.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4FCGH@85020|Dermabacteraceae	201174|Actinobacteria	F	Adenosine/AMP deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
SRR25158535_k127_1572237_0	1206101.AZXC01000027_gene5569	7.728e-173	550.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158535_k127_1572237_2	446466.Cfla_1719	4.717e-63	223.0	2DM5T@1|root,31U0Y@2|Bacteria,2I89A@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
SRR25158535_k127_1572237_4	1380346.JNIH01000008_gene1376	5.495e-42	160.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
SRR25158535_k127_1572237_1	106370.Francci3_3778	6.277e-144	472.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4ERKP@85013|Frankiales	201174|Actinobacteria	H	PFAM Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_1572237_3	1032480.MLP_16970	5.756e-52	186.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DNMR@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_15727_1	426716.JOAJ01000009_gene5865	3.398e-38	146.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4FU3Q@85025|Nocardiaceae	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158535_k127_15727_0	590998.Celf_0031	4.97e-134	448.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4F0UK@85016|Cellulomonadaceae	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
SRR25158535_k127_15727_2	103733.JNYO01000004_gene7429	2.375e-22	103.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DY16@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_1574685_0	1298863.AUEP01000004_gene2035	5.634e-177	565.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4DNWF@85009|Propionibacteriales	201174|Actinobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SRR25158535_k127_1577905_2	351607.Acel_0401	1.117e-98	330.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4ES54@85013|Frankiales	201174|Actinobacteria	E	PFAM Pyruvate carboxyltransferase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SRR25158535_k127_1577905_0	644966.Tmar_1390	2.136e-217	701.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,24BNG@186801|Clostridia,3WD5E@538999|Clostridiales incertae sedis	186801|Clostridia	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158535_k127_1577905_1	1108045.GORHZ_068_00060	8.548e-137	483.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4GA3N@85026|Gordoniaceae	201174|Actinobacteria	I	Biotin-lipoyl like	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158535_k127_1577905_5	58123.JOFJ01000029_gene1154	1.259e-22	102.0	COG2172@1|root,COG2172@2|Bacteria,2I12C@201174|Actinobacteria,4EK73@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
SRR25158535_k127_1577905_4	1169161.KB897717_gene2950	2.069e-71	262.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	yngF	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158535_k127_1577905_3	1077144.AGFF01000007_gene1799	5.258e-86	293.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158535_k127_1578553_3	1380390.JIAT01000010_gene3905	2.274e-25	109.0	COG1670@1|root,COG1670@2|Bacteria,2HP6V@201174|Actinobacteria,4CTRA@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158535_k127_1578553_4	479434.Sthe_2602	1.197e-08	58.0	COG1670@1|root,COG1670@2|Bacteria,2G8SC@200795|Chloroflexi,27YIG@189775|Thermomicrobia	189775|Thermomicrobia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158535_k127_1578553_0	543632.JOJL01000102_gene7256	1.326e-153	498.0	COG4584@1|root,COG4584@2|Bacteria,2GM4J@201174|Actinobacteria,4DET8@85008|Micromonosporales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SRR25158535_k127_1578553_1	1146883.BLASA_4403	1.258e-114	374.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4EVJ8@85013|Frankiales	201174|Actinobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SRR25158535_k127_1578553_2	1120950.KB892815_gene6945	2.389e-107	357.0	COG3464@1|root,COG3464@2|Bacteria,2IQ9H@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
SRR25158535_k127_1579043_1	479434.Sthe_0342	9.902e-107	351.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
SRR25158535_k127_1579043_2	1157637.KB892097_gene1219	1.28e-77	264.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria	201174|Actinobacteria	M	Oxidoreductase molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
SRR25158535_k127_1579043_0	383372.Rcas_0710	8.269e-247	772.0	COG0166@1|root,COG0166@2|Bacteria,2G5ZM@200795|Chloroflexi,376U7@32061|Chloroflexia	32061|Chloroflexia	F	glucose-6-phosphate isomerase activity	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
SRR25158535_k127_1580611_4	358681.BBR47_02280	3.094e-24	108.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,26WYM@186822|Paenibacillaceae	91061|Bacilli	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SRR25158535_k127_1580611_1	1236902.ANAS01000019_gene4262	3.346e-104	352.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4EHH4@85012|Streptosporangiales	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158535_k127_1580611_2	1123320.KB889574_gene5569	6.325e-46	168.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158535_k127_1580611_3	1121877.JQKF01000009_gene544	3.745e-43	161.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CN5R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158535_k127_1580611_0	1120950.KB892746_gene3613	9.023e-121	390.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4DN2A@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158535_k127_1587926_1	298655.KI912266_gene2344	6.526e-71	244.0	COG1556@1|root,COG1556@2|Bacteria,2GNUJ@201174|Actinobacteria,4EVGF@85013|Frankiales	201174|Actinobacteria	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
SRR25158535_k127_1587926_0	1123024.AUII01000001_gene2905	1.631e-88	300.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DXC6@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_1587926_2	330084.JNYZ01000023_gene3573	4.335e-17	82.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4DZF1@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_158817_2	525368.HMPREF0591_4472	1.726e-28	117.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria,236H8@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase, catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,Mu-transpos_C,rve
SRR25158535_k127_158817_1	525368.HMPREF0591_4482	2.733e-30	130.0	COG3677@1|root,COG3677@2|Bacteria,2IGIB@201174|Actinobacteria,239RI@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_158817_0	1048339.KB913029_gene1820	5.352e-31	129.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4EVG9@85013|Frankiales	201174|Actinobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158535_k127_1603855_1	543632.JOJL01000022_gene867	2.403e-16	78.0	COG1983@1|root,COG1983@2|Bacteria,2HUTN@201174|Actinobacteria,4DFZ7@85008|Micromonosporales	201174|Actinobacteria	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
SRR25158535_k127_1603855_0	710111.FraQA3DRAFT_1340	4.907e-58	218.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4EV73@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158535_k127_1603855_2	103733.JNYO01000017_gene3188	4.587e-05	46.0	COG1357@1|root,COG3293@1|root,COG1357@2|Bacteria,COG3293@2|Bacteria,2GNJ9@201174|Actinobacteria,4E5ZI@85010|Pseudonocardiales	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_1608871_3	479434.Sthe_2288	6.314e-52	187.0	COG0500@1|root,COG2226@2|Bacteria,2G9GR@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158535_k127_1608871_2	1123023.JIAI01000001_gene6028	9.735e-79	265.0	COG3871@1|root,COG3871@2|Bacteria,2I3KD@201174|Actinobacteria,4E3CA@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_1608871_0	455632.SGR_2373	4.261e-129	422.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4185V@629295|Streptomyces griseus group	201174|Actinobacteria	D	Iron-sulfur cluster assembly protein	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SRR25158535_k127_1608871_1	1179773.BN6_25550	3.103e-118	399.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4E059@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phytoene dehydrogenase-like oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158535_k127_1608871_4	706587.Desti_4719	1.647e-30	123.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158535_k127_1619636_2	1101189.AQUO01000001_gene2997	2.259e-18	86.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2PUCX@265|Paracoccus	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158535_k127_1619636_1	264732.Moth_2132	1.129e-39	156.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,42G8D@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
SRR25158535_k127_1619636_3	1038867.AXAY01000034_gene2	9.175e-12	76.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Hydrolase_4,Trans_reg_C
SRR25158535_k127_1619636_0	1122622.ATWJ01000008_gene2607	6.674e-100	337.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,4FJXN@85021|Intrasporangiaceae	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158535_k127_163508_2	749927.AMED_6110	8.266e-19	86.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4E1N9@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Transposase, IS111A IS1328 IS1533, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_163508_1	1122138.AQUZ01000001_gene1825	1.269e-127	434.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_163508_0	234267.Acid_5269	4.654e-148	481.0	COG3391@1|root,COG3391@2|Bacteria,3Y7A2@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
SRR25158535_k127_163508_3	644966.Tmar_0126	1.745e-13	75.0	COG0558@1|root,COG1213@1|root,COG0558@2|Bacteria,COG1213@2|Bacteria,1V33I@1239|Firmicutes	1239|Firmicutes	IM	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.7.74,2.7.8.34	ko:K07281,ko:K07291	ko00562,map00562	-	R09669,R09670	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,NTP_transf_3
SRR25158535_k127_163989_0	471852.Tcur_3753	3.275e-93	333.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4EHP5@85012|Streptosporangiales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158535_k127_1642701_2	665577.JH993790_gene5910	8.27e-12	66.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158535_k127_1642701_1	1957.JODX01000018_gene1755	2.359e-104	357.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158535_k127_1642701_0	1121946.AUAX01000019_gene7792	4.39e-136	442.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4DD66@85008|Micromonosporales	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158535_k127_1642800_1	1380390.JIAT01000009_gene2066	5.904e-26	121.0	COG1376@1|root,COG1376@2|Bacteria,2HNXN@201174|Actinobacteria,4CQ6A@84995|Rubrobacteria	84995|Rubrobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SRR25158535_k127_1642800_0	1394178.AWOO02000093_gene8076	3.066e-117	385.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria,4EGUG@85012|Streptosporangiales	201174|Actinobacteria	E	Helix-hairpin-helix domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
SRR25158535_k127_1652082_5	935845.JADQ01000063_gene145	3.852e-26	108.0	COG0693@1|root,COG0693@2|Bacteria,1V1CG@1239|Firmicutes,4HFRX@91061|Bacilli,26QH2@186822|Paenibacillaceae	91061|Bacilli	S	Glutamine amidotransferase	yraA	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158535_k127_1652082_4	1382356.JQMP01000003_gene1667	1.331e-40	164.0	COG2141@1|root,COG2141@2|Bacteria,2GB9A@200795|Chloroflexi,27Y8J@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_1652082_1	1120949.KB903315_gene252	7.594e-104	351.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria,4DII5@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158535_k127_1652082_0	526225.Gobs_2398	7.61e-183	583.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EVDD@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_1652082_2	345341.KUTG_00776	2.878e-67	240.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,4E1G7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158535_k127_1652082_6	452652.KSE_52510	1.022e-09	61.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria,2M5NA@2063|Kitasatospora	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_1652082_7	452652.KSE_52510	4.458e-09	61.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria,2M5NA@2063|Kitasatospora	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_1652082_3	1120797.KB908255_gene544	5.826e-51	198.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,234A6@1762|Mycobacteriaceae	201174|Actinobacteria	E	Monoamine oxidase	aofH_1	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158535_k127_1654018_2	1129794.C427_2486	7.644e-37	144.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,1SZQR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158535_k127_1654018_1	478741.JAFS01000002_gene87	1.074e-50	184.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
SRR25158535_k127_1654018_0	656024.FsymDg_1650	7.421e-293	912.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
SRR25158535_k127_165678_8	196162.Noca_1632	1.264e-27	112.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4DPPU@85009|Propionibacteriales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158535_k127_165678_4	926569.ANT_01260	2.34e-119	391.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158535_k127_165678_1	405948.SACE_5343	2.301e-238	764.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DY4J@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158535_k127_165678_7	1120949.KB903294_gene4398	1.842e-45	174.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4DDF0@85008|Micromonosporales	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_165678_0	471852.Tcur_1655	2.139e-266	825.0	COG1850@1|root,COG1850@2|Bacteria,2HFXU@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the RuBisCO large chain family	cbbL	-	4.1.1.39,5.3.2.5	ko:K01601,ko:K08965	ko00270,ko00630,ko00710,ko01100,ko01120,ko01200,map00270,map00630,map00710,map01100,map01120,map01200	M00034,M00165,M00166,M00532	R00024,R03140,R07393	RC00172,RC00859,RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
SRR25158535_k127_165678_5	471852.Tcur_1656	1.911e-63	228.0	COG4451@1|root,COG4451@2|Bacteria,2IIFC@201174|Actinobacteria	201174|Actinobacteria	C	Ribulose bisphosphate carboxylase, small chain	cbxSC	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
SRR25158535_k127_165678_3	882083.SacmaDRAFT_1953	1.49e-133	435.0	COG0572@1|root,COG0572@2|Bacteria,2I98W@201174|Actinobacteria,4E9H9@85010|Pseudonocardiales	201174|Actinobacteria	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.19,2.7.1.48	ko:K00855,ko:K00876	ko00240,ko00710,ko00983,ko01100,ko01120,ko01200,map00240,map00710,map00983,map01100,map01120,map01200	M00165,M00166	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01523,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158535_k127_165678_6	471852.Tcur_1654	6.446e-60	220.0	COG0583@1|root,COG0583@2|Bacteria,2GMES@201174|Actinobacteria,4EM2X@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SRR25158535_k127_165678_9	639030.JHVA01000001_gene3028	1.692e-25	123.0	COG1592@1|root,COG1592@2|Bacteria,3Y5YA@57723|Acidobacteria,2JK5H@204432|Acidobacteriia	204432|Acidobacteriia	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SRR25158535_k127_165678_2	272844.PAB0938	1.987e-166	539.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR25158535_k127_165678_10	58123.JOFJ01000027_gene2790	2.278e-20	92.0	COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4EN0D@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158535_k127_1658373_4	1313172.YM304_19800	1.489e-30	135.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CNA7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158535_k127_1658373_2	351607.Acel_1702	1.923e-63	232.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4ET4R@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
SRR25158535_k127_1658373_0	1123023.JIAI01000029_gene4428	1.757e-145	466.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4DXUJ@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
SRR25158535_k127_1658373_1	1380393.JHVP01000003_gene899	8.223e-68	251.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4ESCW@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
SRR25158535_k127_1658373_3	446470.Snas_2629	4.512e-36	145.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4EXPK@85014|Glycomycetales	201174|Actinobacteria	K	Transcriptional regulator	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
SRR25158535_k127_1660974_6	649638.Trad_0782	9.598e-39	164.0	COG2166@1|root,COG2166@2|Bacteria,1WK00@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
SRR25158535_k127_1660974_0	263358.VAB18032_04695	5.725e-145	467.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4D8QA@85008|Micromonosporales	201174|Actinobacteria	P	Sulfurtransferase	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158535_k127_1660974_3	1236902.ANAS01000005_gene4952	9.932e-47	178.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4EH6P@85012|Streptosporangiales	201174|Actinobacteria	T	Protein phosphatase 2C	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SRR25158535_k127_1660974_4	526225.Gobs_3902	3.206e-46	187.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4ERFR@85013|Frankiales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0033554,GO:0042221,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SRR25158535_k127_1660974_5	485913.Krac_7251	4.449e-40	169.0	COG0454@1|root,COG0456@2|Bacteria,2G965@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_1660974_2	1521187.JPIM01000028_gene1595	2.595e-70	254.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_1660974_1	711393.AYRX01000012_gene3257	9.008e-71	251.0	COG0745@1|root,COG0745@2|Bacteria,2GMP1@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1660974_7	479432.Sros_3874	1.202e-29	118.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria,4EK19@85012|Streptosporangiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158535_k127_1661781_1	1123392.AQWL01000002_gene1963	9.83e-07	56.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,1MX0D@1224|Proteobacteria,2VR9V@28216|Betaproteobacteria,1KSRS@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Adenylylsulphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
SRR25158535_k127_1661781_0	266117.Rxyl_0963	4.329e-217	681.0	COG0155@1|root,COG0155@2|Bacteria,2GJRN@201174|Actinobacteria,4CQKT@84995|Rubrobacteria	84995|Rubrobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2	ko:K00366,ko:K00381	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
SRR25158535_k127_1662644_1	1179773.BN6_53490	0.0	1056.0	COG3696@1|root,COG3696@2|Bacteria,2H303@201174|Actinobacteria,4EF0N@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158535_k127_1662644_2	1089545.KB913037_gene2295	5.054e-24	115.0	2DS99@1|root,33F32@2|Bacteria,2GXTE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1662644_0	1179773.BN6_53510	0.0	1418.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4EE9U@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158535_k127_1666449_1	1449976.KALB_2853	1.5e-54	216.0	COG0819@1|root,COG0819@2|Bacteria,2I9CY@201174|Actinobacteria,4E40C@85010|Pseudonocardiales	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	-	-	-	-	-	-	-	-	-	-	-	-	TENA_THI-4
SRR25158535_k127_1666449_0	1449976.KALB_2854	7.156e-197	625.0	COG1457@1|root,COG1457@2|Bacteria	2|Bacteria	F	cytosine transport	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
SRR25158535_k127_1669253_2	656024.FsymDg_3117	1.918e-105	356.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4ERN7@85013|Frankiales	201174|Actinobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
SRR25158535_k127_1669253_0	469383.Cwoe_3774	7.513e-140	461.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CP75@84995|Rubrobacteria	84995|Rubrobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_1669253_1	105420.BBPO01000019_gene5556	7.053e-111	394.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,2NEW8@228398|Streptacidiphilus	201174|Actinobacteria	M	Mur ligase family, catalytic domain	murF	GO:0008150,GO:0040007	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SRR25158535_k127_1670390_8	706587.Desti_5521	4.825e-25	106.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,42TER@68525|delta/epsilon subdivisions,2WPKW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
SRR25158535_k127_1670390_3	749414.SBI_07096	7.399e-88	306.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158535_k127_1670390_1	1449976.KALB_1710	4.432e-96	339.0	COG0701@1|root,COG0701@2|Bacteria,2GJQ0@201174|Actinobacteria,4DY2Z@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SRR25158535_k127_1670390_7	66897.DJ64_26535	2.089e-33	148.0	COG3689@1|root,COG3689@2|Bacteria,2GZEU@201174|Actinobacteria	201174|Actinobacteria	S	TIGRFAM TIGR03943 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1980
SRR25158535_k127_1670390_10	211114.JOEF01000002_gene3998	7.214e-20	104.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4E3EB@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158535_k127_1670390_6	1122138.AQUZ01000040_gene6213	1.865e-58	211.0	COG0739@1|root,COG0739@2|Bacteria,2IBVX@201174|Actinobacteria	201174|Actinobacteria	M	Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158535_k127_1670390_5	994479.GL877879_gene5574	1.89e-71	263.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4DY5S@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM YibE F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
SRR25158535_k127_1670390_4	68219.JNXI01000019_gene7624	1.706e-71	251.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria	201174|Actinobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158535_k127_1670390_9	469371.Tbis_0512	1.138e-20	103.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria,4DZUB@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt uptake substrate-specific transmembrane region	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
SRR25158535_k127_1670390_2	1463920.JOGB01000004_gene4592	8.756e-89	299.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria	201174|Actinobacteria	P	Cobalt ABC transporter	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SRR25158535_k127_1670390_0	1352941.M877_24675	2.654e-117	396.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria	201174|Actinobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
SRR25158535_k127_1676458_1	1116232.AHBF01000137_gene1871	4.089e-33	139.0	COG1231@1|root,COG1231@2|Bacteria,2I8ZQ@201174|Actinobacteria	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158535_k127_1676458_0	266117.Rxyl_2514	3.909e-41	155.0	COG3293@1|root,COG3293@2|Bacteria,2IKID@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
SRR25158535_k127_1680672_1	1121334.KB911070_gene1273	2.941e-18	90.0	COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,24MYP@186801|Clostridia,3WRD7@541000|Ruminococcaceae	186801|Clostridia	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158535_k127_1680672_0	234267.Acid_3078	2.583e-145	467.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_1685280_0	1122611.KB903985_gene3775	4.304e-99	331.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4EHVJ@85012|Streptosporangiales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8,fn3_5
SRR25158535_k127_1685280_1	1267535.KB906767_gene724	5.169e-20	99.0	2DT50@1|root,33IQQ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040
SRR25158535_k127_1691363_2	543632.JOJL01000008_gene5599	1.255e-27	122.0	2DBP2@1|root,2ZA71@2|Bacteria,2H3R7@201174|Actinobacteria,4DHXU@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1691363_3	66875.JODY01000002_gene4920	0.0005076	46.0	COG1020@1|root,COG1028@1|root,COG3321@1|root,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
SRR25158535_k127_1691363_0	1237500.ANBA01000017_gene1583	2.531e-92	308.0	COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SRR25158535_k127_1691363_1	1261545.MBE-HAL_2324	3.868e-88	315.0	COG0477@1|root,arCOG02682@2157|Archaea,2XWP6@28890|Euryarchaeota,23Z4U@183963|Halobacteria	183963|Halobacteria	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SRR25158535_k127_169267_4	266940.Krad_1406	8.344e-41	163.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
SRR25158535_k127_169267_3	1048339.KB913029_gene3519	7.419e-48	181.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4ESE0@85013|Frankiales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SRR25158535_k127_169267_5	298655.KI912267_gene6705	6.217e-40	170.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4ESKU@85013|Frankiales	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158535_k127_169267_2	28042.GU90_17700	4.025e-52	187.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4E3E1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SRR25158535_k127_169267_1	1504822.CCNO01000015_gene962	2.752e-72	261.0	COG0336@1|root,COG0336@2|Bacteria,2NP5G@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA_m1G_MT
SRR25158535_k127_169267_6	710111.FraQA3DRAFT_5797	1.279e-33	144.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4ET25@85013|Frankiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SRR25158535_k127_169267_8	867903.ThesuDRAFT_00296	2.594e-14	82.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3WDJD@538999|Clostridiales incertae sedis	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SRR25158535_k127_169267_7	411474.COPEUT_00362	1.804e-22	113.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SRR25158535_k127_169267_0	219305.MCAG_04263	1.031e-165	534.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4DA22@85008|Micromonosporales	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SRR25158535_k127_17007_5	512565.AMIS_48330	1.443e-52	194.0	COG2382@1|root,COG2382@2|Bacteria,2HWND@201174|Actinobacteria,4DJN7@85008|Micromonosporales	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
SRR25158535_k127_17007_3	1120949.KB903295_gene2238	4.808e-102	340.0	COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SRR25158535_k127_17007_2	1449347.JQLN01000004_gene7212	3.342e-147	470.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,2M0PK@2063|Kitasatospora	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_17007_1	543632.JOJL01000004_gene4106	1.416e-162	524.0	COG1181@1|root,COG1181@2|Bacteria,2HP1M@201174|Actinobacteria,4DHKT@85008|Micromonosporales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C
SRR25158535_k127_17007_8	1254432.SCE1572_15965	1.874e-18	96.0	COG3214@1|root,COG3214@2|Bacteria,1R9AI@1224|Proteobacteria,43400@68525|delta/epsilon subdivisions,2X4C8@28221|Deltaproteobacteria,2YYQU@29|Myxococcales	28221|Deltaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_17007_6	35754.JNYJ01000018_gene9603	2.263e-34	144.0	2BCVG@1|root,326G8@2|Bacteria,2GQZY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3995)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3995
SRR25158535_k127_17007_7	211114.JOEF01000026_gene367	8.32e-20	97.0	COG3409@1|root,COG3409@2|Bacteria,2HUBB@201174|Actinobacteria,4E7IY@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_17007_4	644966.Tmar_1488	1.301e-61	235.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	coxF	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
SRR25158535_k127_17007_0	502025.Hoch_2000	3.728e-170	539.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
SRR25158535_k127_1710701_1	1203190.CAJP01000040_gene1399	5.329e-44	167.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,22K93@1653|Corynebacteriaceae	201174|Actinobacteria	E	acetylornithine aminotransferase	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_1710701_2	521096.Tpau_2398	1.121e-28	128.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
SRR25158535_k127_1710701_0	867903.ThesuDRAFT_02026	1.446e-120	410.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WCR7@538999|Clostridiales incertae sedis	186801|Clostridia	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SRR25158535_k127_1711886_0	436229.JOEH01000019_gene6707	0.0	1300.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,2NECJ@228398|Streptacidiphilus	201174|Actinobacteria	L	DEAD/H associated	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158535_k127_171763_1	1380394.JADL01000010_gene4323	1.211e-108	378.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,2TUJB@28211|Alphaproteobacteria,2JQGJ@204441|Rhodospirillales	204441|Rhodospirillales	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SRR25158535_k127_171763_0	1313172.YM304_35710	3.87e-129	421.0	COG1410@1|root,COG1410@2|Bacteria,2IC7C@201174|Actinobacteria	201174|Actinobacteria	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158535_k127_171763_2	570967.JMLV01000010_gene1278	1.743e-64	229.0	28I8Y@1|root,2Z8BR@2|Bacteria,1MXN1@1224|Proteobacteria,2TRAQ@28211|Alphaproteobacteria,2JS8U@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
SRR25158535_k127_171763_3	1123399.AQVE01000012_gene2962	2.199e-17	82.0	COG5012@1|root,COG5012@2|Bacteria,1QDZ3@1224|Proteobacteria,1RYST@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
SRR25158535_k127_1718372_1	1348663.KCH_18540	6.496e-101	347.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,2M05I@2063|Kitasatospora	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158535_k127_1718372_0	1348663.KCH_18550	8.002e-128	417.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,2M0XN@2063|Kitasatospora	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_1718372_2	1278073.MYSTI_04554	7.082e-31	126.0	COG1846@1|root,COG1846@2|Bacteria,1NKV4@1224|Proteobacteria,42RNI@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158535_k127_1718822_0	298653.Franean1_1280	4.177e-67	236.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1718822_3	929713.NIASO_18560	2.054e-07	63.0	2E7DJ@1|root,331WN@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
SRR25158535_k127_1718822_1	292459.STH2612	1.61e-37	160.0	COG0642@1|root,COG2205@2|Bacteria,1TRAB@1239|Firmicutes,24DV3@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
SRR25158535_k127_1718822_2	1214101.BN159_3433	1.085e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_1719203_0	1184607.AUCHE_05_04270	1.172e-183	585.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158535_k127_1719203_1	595460.RRSWK_03756	1.242e-105	373.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158535_k127_1719203_2	1240349.ANGC01000047_gene4661	8.31e-19	90.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria,4G0EJ@85025|Nocardiaceae	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158535_k127_172050_2	1313172.YM304_31100	6.561e-28	123.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158535_k127_172050_0	1110697.NCAST_19_00610	5.647e-164	530.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FXKQ@85025|Nocardiaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SRR25158535_k127_172050_1	1123320.KB889723_gene7516	4.993e-156	510.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	ctpE	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
SRR25158535_k127_1728173_0	1463825.JNXC01000003_gene3880	4.045e-150	486.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4DXNY@85010|Pseudonocardiales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
SRR25158535_k127_1728173_5	234267.Acid_5182	3.305e-13	77.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
SRR25158535_k127_1728173_4	1123065.ATWL01000002_gene1695	2.628e-18	90.0	COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria	201174|Actinobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
SRR25158535_k127_1728173_1	479432.Sros_2119	6.098e-82	289.0	COG0618@1|root,COG0618@2|Bacteria,2GN9Z@201174|Actinobacteria,4EHHU@85012|Streptosporangiales	201174|Actinobacteria	S	DHH family	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SRR25158535_k127_1728173_3	1210046.B277_03400	8.392e-58	219.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4FEDD@85021|Intrasporangiaceae	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SRR25158535_k127_1728173_2	1121926.AXWO01000016_gene4123	1.718e-79	282.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4EY84@85014|Glycomycetales	201174|Actinobacteria	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SRR25158535_k127_1732617_0	1089545.KB913037_gene2858	3.076e-203	642.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158535_k127_1732617_1	1121272.KB903289_gene4319	2.388e-117	383.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2GMG7@201174|Actinobacteria,4D96P@85008|Micromonosporales	201174|Actinobacteria	KT	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
SRR25158535_k127_1732617_2	1089553.Tph_c09300	7.388e-46	179.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42F7P@68295|Thermoanaerobacterales	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SRR25158535_k127_1732617_3	1246448.ANAZ01000020_gene2847	1.259e-05	55.0	COG3745@1|root,COG3745@2|Bacteria,2GQJH@201174|Actinobacteria,4EKC2@85012|Streptosporangiales	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,RcpC,SAF
SRR25158535_k127_174825_2	1463936.JOJI01000005_gene4122	2.626e-20	92.0	2EIST@1|root,33CI4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_174825_0	216594.MMAR_0936	0.0	1399.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,23C6I@1762|Mycobacteriaceae	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158535_k127_174825_1	1386089.N865_15125	9.547e-122	402.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria,4FH53@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1757999_2	548479.HMPREF0573_11669	7.32e-54	196.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4D3BN@85005|Actinomycetales	201174|Actinobacteria	T	Response regulator receiver domain protein	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
SRR25158535_k127_1757999_0	1108045.GORHZ_242_00030	2.159e-81	274.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria	201174|Actinobacteria	L	resolvase	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
SRR25158535_k127_1757999_1	1380386.JIAW01000019_gene2295	1.665e-61	219.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,2382Y@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1758373_2	1122933.JNIY01000012_gene1316	1.627e-41	177.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria	201174|Actinobacteria	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_1758373_0	266117.Rxyl_1742	9.088e-94	318.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_1758373_1	485913.Krac_5141	3.427e-83	295.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_1779051_0	981369.JQMJ01000001_gene6805	1.142e-223	709.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria,2NKMD@228398|Streptacidiphilus	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_1779458_7	469383.Cwoe_3307	3.204e-83	301.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158535_k127_1779458_3	471852.Tcur_2301	1.774e-107	354.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EH5C@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1779458_2	710111.FraQA3DRAFT_0829	2.252e-199	649.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4EXBT@85013|Frankiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_1779458_6	867845.KI911784_gene145	2.331e-87	293.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SRR25158535_k127_1779458_0	867903.ThesuDRAFT_01477	3.701e-243	800.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,24Z0I@186801|Clostridia	186801|Clostridia	H	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
SRR25158535_k127_1779458_1	266117.Rxyl_2833	4.031e-225	711.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CPWI@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_1779458_4	266117.Rxyl_2832	1.325e-99	357.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CRXQ@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_1779458_5	266117.Rxyl_2831	1.503e-95	316.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria	201174|Actinobacteria	C	Fe-S oxidoreductase	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
SRR25158535_k127_1779982_3	65497.JODV01000007_gene544	2.704e-07	56.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4E6G1@85010|Pseudonocardiales	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_1779982_0	298655.KI912266_gene2835	4.097e-267	865.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2ICGU@201174|Actinobacteria	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158535_k127_1779982_1	298655.KI912266_gene2834	9.662e-106	349.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_1779982_2	525368.HMPREF0591_5660	1.195e-25	112.0	COG0642@1|root,COG2205@2|Bacteria,2I2QY@201174|Actinobacteria,23733@1762|Mycobacteriaceae	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_1784174_0	66373.JOFQ01000003_gene5771	2.851e-63	229.0	29AJG@1|root,2ZXJF@2|Bacteria,2GYRJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
SRR25158535_k127_1784174_4	590998.Celf_1282	1.148e-13	78.0	COG3187@1|root,COG3187@2|Bacteria,2GZ1J@201174|Actinobacteria	201174|Actinobacteria	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
SRR25158535_k127_1784174_2	1298863.AUEP01000005_gene2686	1.705e-50	186.0	2EAFX@1|root,334J9@2|Bacteria,2IJSF@201174|Actinobacteria,4DUK6@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1784174_3	1122138.AQUZ01000001_gene1614	4.947e-50	187.0	COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,2GPKD@201174|Actinobacteria,4DRG1@85009|Propionibacteriales	201174|Actinobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GerE
SRR25158535_k127_1784174_5	1122138.AQUZ01000001_gene1614	5.887e-11	65.0	COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,2GPKD@201174|Actinobacteria,4DRG1@85009|Propionibacteriales	201174|Actinobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GerE
SRR25158535_k127_1784174_1	1122138.AQUZ01000001_gene1613	3.776e-58	213.0	COG0662@1|root,COG0662@2|Bacteria,2IEY0@201174|Actinobacteria,4DVK8@85009|Propionibacteriales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_1784174_6	1079986.JH164867_gene2679	1.07e-08	56.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_1791742_14	1206744.BAGL01000033_gene220	2.191e-45	167.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4FZB8@85025|Nocardiaceae	201174|Actinobacteria	I	Coenzyme A transferase	catI	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
SRR25158535_k127_1791742_2	446462.Amir_3076	1.023e-180	606.0	COG0160@1|root,COG0160@2|Bacteria,2GIS9@201174|Actinobacteria,4DY9R@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,4.1.1.64	ko:K00596,ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_1791742_1	446462.Amir_3077	1.26e-214	703.0	COG1012@1|root,COG1012@2|Bacteria,2HF1C@201174|Actinobacteria,4EA29@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158535_k127_1791742_8	1137269.AZWL01000001_gene5263	6.43e-92	327.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria	201174|Actinobacteria	E	amidohydrolase	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
SRR25158535_k127_1791742_6	309801.trd_A0888	1.658e-105	370.0	COG0465@1|root,COG0465@2|Bacteria,2G5JA@200795|Chloroflexi,27YWY@189775|Thermomicrobia	189775|Thermomicrobia	D	Peptidase family M41	-	-	-	-	-	-	-	-	-	-	-	-	AAA,Peptidase_M41
SRR25158535_k127_1791742_4	477641.MODMU_2519	6.49e-121	402.0	COG3319@1|root,COG3319@2|Bacteria,2GJ5V@201174|Actinobacteria	201174|Actinobacteria	Q	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
SRR25158535_k127_1791742_3	477641.MODMU_2520	3.711e-148	502.0	COG1404@1|root,COG1404@2|Bacteria,2HF5H@201174|Actinobacteria,4EWKQ@85013|Frankiales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158535_k127_1791742_5	1122611.KB903939_gene386	9.135e-115	381.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4EFV3@85012|Streptosporangiales	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SRR25158535_k127_1791742_17	660470.Theba_2105	1.598e-05	56.0	COG1597@1|root,COG1597@2|Bacteria,2GCWI@200918|Thermotogae	200918|Thermotogae	I	diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158535_k127_1791742_0	471852.Tcur_2321	5.393e-250	819.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4EH6A@85012|Streptosporangiales	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
SRR25158535_k127_1791742_9	298654.FraEuI1c_0732	1.405e-59	217.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4ESXC@85013|Frankiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
SRR25158535_k127_1791742_10	1356852.N008_21305	3.021e-54	197.0	COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,47Q9R@768503|Cytophagia	976|Bacteroidetes	M	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
SRR25158535_k127_1791742_12	1229780.BN381_400031	5.958e-49	185.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,3UWSI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SRR25158535_k127_1791742_18	667014.Thein_1588	1.881e-05	53.0	COG1826@1|root,COG1826@2|Bacteria,2GIP7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158535_k127_1791742_11	326424.FRAAL2881	1.839e-52	208.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4ESDG@85013|Frankiales	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158535_k127_1791742_13	1122611.KB904018_gene6993	9.881e-48	183.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,4EFRP@85012|Streptosporangiales	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
SRR25158535_k127_1791742_15	1380763.BG53_12910	1.661e-38	152.0	COG2345@1|root,COG2345@2|Bacteria,1V5Q5@1239|Firmicutes,4HHMX@91061|Bacilli,26U3B@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,HTH_DeoR
SRR25158535_k127_1791742_7	477974.Daud_1285	1.325e-92	316.0	COG3502@1|root,COG3502@2|Bacteria,1TQW1@1239|Firmicutes,24952@186801|Clostridia,26116@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
SRR25158535_k127_1791742_16	525904.Tter_0205	1.159e-12	81.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	wgeF	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158535_k127_1792013_3	882083.SacmaDRAFT_4399	1.442e-26	124.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_1792013_0	351607.Acel_1119	1.25e-136	460.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4ERFP@85013|Frankiales	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_1792013_1	882083.SacmaDRAFT_4397	1.227e-119	393.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4DYJ1@85010|Pseudonocardiales	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_1792013_2	1123024.AUII01000003_gene3334	3.527e-81	275.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DXT5@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_1792723_3	337191.KTR9_3590	4.247e-32	134.0	COG4275@1|root,COG4275@2|Bacteria,2IK0B@201174|Actinobacteria,4GFWZ@85026|Gordoniaceae	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SRR25158535_k127_1792723_1	591159.ACEZ01000200_gene2508	4.958e-49	184.0	COG4275@1|root,COG4275@2|Bacteria,2IPJU@201174|Actinobacteria	201174|Actinobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1792723_0	1242864.D187_009165	3.688e-86	297.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NAQ@68525|delta/epsilon subdivisions,2WJPX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
SRR25158535_k127_1792723_4	211114.JOEF01000036_gene1806	4.511e-23	109.0	COG3920@1|root,COG3920@2|Bacteria,2IT7M@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,STAS_2
SRR25158535_k127_1792723_2	1128421.JAGA01000002_gene533	1.101e-47	181.0	COG3214@1|root,COG3214@2|Bacteria,2NQD2@2323|unclassified Bacteria	2|Bacteria	S	Winged helix DNA-binding domain	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
SRR25158535_k127_1797149_5	405948.SACE_2418	1.087e-16	89.0	COG0517@1|root,COG0517@2|Bacteria,2I3TG@201174|Actinobacteria,4EC77@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158535_k127_1797149_0	1254432.SCE1572_36930	1.039e-235	754.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2YX9E@29|Myxococcales	28221|Deltaproteobacteria	P	Hemerythrin HHE cation binding domain	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
SRR25158535_k127_1797149_6	1158292.JPOE01000002_gene1601	8.47e-11	71.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,1KMF3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	sirA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158535_k127_1797149_2	1304275.C41B8_12424	2.961e-126	448.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the class I fructose-bisphosphate aldolase family	alf1	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
SRR25158535_k127_1797149_1	517418.Ctha_0151	9.147e-172	548.0	COG0205@1|root,COG0205@2|Bacteria,1FDFG@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SRR25158535_k127_1797149_4	1298880.AUEV01000003_gene3424	1.491e-18	88.0	COG1082@1|root,COG1082@2|Bacteria,2I2WE@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158535_k127_1797149_3	1122611.KB903996_gene7639	7.767e-26	115.0	COG1082@1|root,COG1082@2|Bacteria,2HMB3@201174|Actinobacteria,4EKZD@85012|Streptosporangiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
SRR25158535_k127_1797149_7	215803.DB30_6912	0.0002061	44.0	COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,43774@68525|delta/epsilon subdivisions,2X3VE@28221|Deltaproteobacteria,2YX8C@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_1797470_4	1114959.SZMC14600_04443	6.032e-11	74.0	COG1051@1|root,COG2062@1|root,COG1051@2|Bacteria,COG2062@2|Bacteria,2I2N2@201174|Actinobacteria,4DZW1@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
SRR25158535_k127_1797470_5	1435356.Y013_04920	2.295e-07	54.0	COG3540@1|root,COG3540@2|Bacteria,2GNZ5@201174|Actinobacteria,4FWZJ@85025|Nocardiaceae	201174|Actinobacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
SRR25158535_k127_1797470_1	1120948.KB903240_gene4151	2.56e-38	155.0	COG3568@1|root,COG3568@2|Bacteria,2HEP6@201174|Actinobacteria,4E819@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158535_k127_1797470_2	561175.KB894096_gene397	2.869e-16	94.0	COG3255@1|root,COG3255@2|Bacteria,2GWVN@201174|Actinobacteria	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158535_k127_1797470_0	1120949.KB903357_gene4848	3.214e-304	942.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	-	GO:0003674,GO:0003824,GO:0004553,GO:0004555,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015927,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0042301,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044464,GO:0046352,GO:0071704,GO:0071944,GO:1901575	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158535_k127_1797470_3	1313172.YM304_10700	6.818e-13	69.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4CMQH@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158535_k127_1807316_2	298655.KI912266_gene1837	7.173e-47	180.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4ESJF@85013|Frankiales	201174|Actinobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
SRR25158535_k127_1807316_1	710111.FraQA3DRAFT_5393	6.727e-58	207.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4ESK5@85013|Frankiales	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
SRR25158535_k127_1807316_0	1160718.SU9_21332	5.21e-77	271.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_1807316_4	1121272.KB903261_gene6134	1.184e-22	104.0	COG0726@1|root,COG0726@2|Bacteria,2HRKN@201174|Actinobacteria,4DGUP@85008|Micromonosporales	201174|Actinobacteria	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
SRR25158535_k127_1807316_3	1179773.BN6_72370	1.375e-38	154.0	COG0726@1|root,COG0726@2|Bacteria,2HRKN@201174|Actinobacteria,4DZ6Y@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
SRR25158535_k127_18077_2	1240349.ANGC01000003_gene1960	1.563e-36	139.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4G8SR@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_18077_3	469371.Tbis_2447	4.949e-29	128.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4EE5Y@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_18077_1	882082.SaccyDRAFT_4082	7.605e-41	155.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4E5MK@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
SRR25158535_k127_18077_0	710111.FraQA3DRAFT_3958	4.407e-57	210.0	COG0500@1|root,COG2226@2|Bacteria,2HCAN@201174|Actinobacteria,4EV4W@85013|Frankiales	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
SRR25158535_k127_1809496_0	706587.Desti_4722	6.501e-52	193.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158535_k127_1809496_1	292459.STH685	1.97e-10	69.0	2EMGM@1|root,33F5A@2|Bacteria,1W2YC@1239|Firmicutes,256C3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_181089_1	882083.SacmaDRAFT_3544	9.916e-80	291.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4E4VR@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_181089_0	479434.Sthe_1273	7.213e-196	623.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_181089_2	1120950.KB892770_gene1358	4.08e-52	189.0	COG3795@1|root,COG3795@2|Bacteria,2IQ6E@201174|Actinobacteria,4DSIH@85009|Propionibacteriales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_181089_3	1068980.ARVW01000001_gene8101	3.274e-20	90.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DXRB@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SRR25158535_k127_1819232_0	883126.HMPREF9710_04097	2.609e-309	954.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2VIFW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SRR25158535_k127_1819232_7	649831.L083_2405	6.229e-61	216.0	COG1522@1|root,COG1522@2|Bacteria,2IG6M@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158535_k127_1819232_6	649831.L083_2404	4.577e-63	249.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	ydzE	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_1819232_11	521393.JH806632_gene881	1.324e-07	65.0	COG3119@1|root,COG3119@2|Bacteria,2H59R@201174|Actinobacteria,4D4KY@85005|Actinomycetales	201174|Actinobacteria	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1819232_5	526225.Gobs_2081	8.238e-66	233.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SRR25158535_k127_1819232_8	367299.JOEE01000011_gene3181	4.039e-33	151.0	COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4FGVH@85021|Intrasporangiaceae	201174|Actinobacteria	F	Peptidase C26	-	-	6.3.5.2	ko:K01951,ko:K07065	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SRR25158535_k127_1819232_3	266117.Rxyl_0057	1.901e-106	355.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4CRPW@84995|Rubrobacteria	84995|Rubrobacteria	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158535_k127_1819232_9	469383.Cwoe_3112	2.953e-20	96.0	2E3FZ@1|root,32YET@2|Bacteria,2IGAC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1819232_10	1123251.ATWM01000003_gene1205	3.282e-15	91.0	COG0355@1|root,COG0355@2|Bacteria,2IHNZ@201174|Actinobacteria,4FHIU@85021|Intrasporangiaceae	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
SRR25158535_k127_1819232_1	656024.FsymDg_3843	8.241e-233	728.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4ES4I@85013|Frankiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SRR25158535_k127_1819232_4	211114.JOEF01000005_gene2180	1.228e-93	315.0	COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4DXM0@85010|Pseudonocardiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SRR25158535_k127_1819232_2	469371.Tbis_0898	2.78e-118	385.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4E0X3@85010|Pseudonocardiales	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SRR25158535_k127_1820658_1	1306990.BARG01000045_gene5376	0.0004311	48.0	COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158535_k127_1820658_0	42256.RradSPS_0631	2.9e-208	666.0	COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SRR25158535_k127_1823578_1	1089546.AQUI01000002_gene3530	1.833e-94	316.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158535_k127_1823578_0	525904.Tter_2056	6.766e-156	498.0	COG1063@1|root,COG1063@2|Bacteria,2NPFX@2323|unclassified Bacteria	2|Bacteria	E	Glucose dehydrogenase C-terminus	gutB_1	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158535_k127_1825754_7	675635.Psed_3442	1.975e-30	135.0	COG4129@1|root,COG4129@2|Bacteria,2GIR7@201174|Actinobacteria,4E5P4@85010|Pseudonocardiales	201174|Actinobacteria	S	Aromatic acid exporter family member 1	-	-	-	-	-	-	-	-	-	-	-	-	ArAE_1
SRR25158535_k127_1825754_6	1449069.JMLO01000004_gene3854	1.035e-34	140.0	COG2050@1|root,COG2050@2|Bacteria,2IJF8@201174|Actinobacteria,4G3K9@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158535_k127_1825754_1	1298880.AUEV01000002_gene1464	5.193e-74	259.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158535_k127_1825754_8	390989.JOEG01000007_gene596	2.962e-30	124.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158535_k127_1825754_4	324925.Ppha_2833	9.452e-36	147.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1825754_9	1122223.KB890687_gene2409	3.644e-21	102.0	COG3708@1|root,COG3708@2|Bacteria	2|Bacteria	K	glyoxalase III activity	yobU	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,DUF3788,GyrI-like,Zn_ribbon_2
SRR25158535_k127_1825754_5	369723.Strop_1904	3.216e-35	139.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4DE1B@85008|Micromonosporales	201174|Actinobacteria	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
SRR25158535_k127_1825754_3	309801.trd_0162	1.28e-50	192.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi,27Y62@189775|Thermomicrobia	189775|Thermomicrobia	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
SRR25158535_k127_1825754_10	498848.TaqDRAFT_4776	6.876e-17	92.0	COG3740@1|root,COG4388@1|root,COG3740@2|Bacteria,COG4388@2|Bacteria,1WN2I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Mu-like prophage I protein	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_Pro
SRR25158535_k127_1825754_0	1068978.AMETH_4196	2.271e-220	698.0	COG0654@1|root,COG0654@2|Bacteria,2GKIN@201174|Actinobacteria,4DY4H@85010|Pseudonocardiales	201174|Actinobacteria	CH	2-polyprenyl-6-methoxyphenol	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158535_k127_1825754_2	1048339.KB913029_gene972	1.319e-68	234.0	COG0491@1|root,COG0491@2|Bacteria,2HTU1@201174|Actinobacteria,4EUGY@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_1825924_1	1068980.ARVW01000001_gene1413	0.000454	52.0	2E534@1|root,32ZWA@2|Bacteria,2I9VJ@201174|Actinobacteria,4E5BX@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2637)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2637
SRR25158535_k127_1825924_0	1123024.AUII01000002_gene909	4.36e-06	52.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_1842512_0	1380390.JIAT01000009_gene1628	2.048e-201	666.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_1842512_3	1463909.KL585969_gene4482	1.487e-39	149.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
SRR25158535_k127_1842512_5	1089547.KB913013_gene3280	3.771e-05	48.0	COG5466@1|root,COG5466@2|Bacteria,4NZG9@976|Bacteroidetes,47W73@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
SRR25158535_k127_1842512_2	269800.Tfu_2625	2.46e-56	204.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4EG7R@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158535_k127_1842512_4	479434.Sthe_3337	2.908e-13	72.0	COG1404@1|root,COG1404@2|Bacteria,2G8R1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Yop-YscD_cpl
SRR25158535_k127_1842512_1	367299.JOEE01000004_gene1170	7.702e-95	320.0	COG0730@1|root,COG0730@2|Bacteria,2GNPE@201174|Actinobacteria,4FFU7@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane transporter protein	cysZ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158535_k127_1846459_1	1122138.AQUZ01000005_gene2725	5.257e-165	534.0	COG0769@1|root,COG0769@2|Bacteria,2GME3@201174|Actinobacteria,4DPYG@85009|Propionibacteriales	201174|Actinobacteria	M	Mur ligase middle domain	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,TPR_5
SRR25158535_k127_1846459_0	1122609.AUGT01000003_gene2286	0.0	1250.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2GN0U@201174|Actinobacteria,4DP39@85009|Propionibacteriales	201174|Actinobacteria	HJM	RimK-like ATP-grasp domain	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
SRR25158535_k127_1846459_3	1120954.ATXE01000001_gene2498	1.333e-85	298.0	COG4242@1|root,COG4242@2|Bacteria,2I93U@201174|Actinobacteria,4DP1Z@85009|Propionibacteriales	201174|Actinobacteria	PQ	Peptidase family S51	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
SRR25158535_k127_1846459_2	1206732.BAGD01000082_gene3543	2.575e-141	466.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4FZVG@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1846459_4	1394178.AWOO02000067_gene217	3.442e-80	273.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria,4EGQB@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_1846459_5	1120950.KB892800_gene1647	1.456e-50	198.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4DQHZ@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_184842_0	1120949.KB903294_gene3990	0.0	1122.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DABZ@85008|Micromonosporales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SRR25158535_k127_184842_3	656024.FsymDg_3098	3.42e-25	116.0	2C2H7@1|root,32Z8Q@2|Bacteria,2ITDR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158535_k127_184842_1	106370.Francci3_4188	1.429e-63	225.0	COG1443@1|root,COG1443@2|Bacteria,2GM26@201174|Actinobacteria,4ESW3@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0071704,GO:0090407,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1745c	NUDIX
SRR25158535_k127_184842_2	1380347.JNII01000008_gene4304	3.149e-55	199.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4ES11@85013|Frankiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SRR25158535_k127_1862957_3	67275.JOAP01000019_gene1386	1.841e-48	181.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
SRR25158535_k127_1862957_4	1122919.KB905561_gene1584	6.968e-28	123.0	COG1011@1|root,COG1011@2|Bacteria,1TRP5@1239|Firmicutes,4HBSP@91061|Bacilli,26QYS@186822|Paenibacillaceae	91061|Bacilli	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158535_k127_1862957_2	485913.Krac_5382	2.391e-76	265.0	2DM3D@1|root,31J5I@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
SRR25158535_k127_1862957_5	443218.AS9A_2782	7.037e-12	74.0	2DZHZ@1|root,31ZDG@2|Bacteria,2IN6I@201174|Actinobacteria,23A9W@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1862957_0	545694.TREPR_0072	1.726e-161	519.0	COG0766@1|root,COG0766@2|Bacteria,2J5JB@203691|Spirochaetes	203691|Spirochaetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SRR25158535_k127_1862957_1	500153.JOEK01000014_gene5658	6.741e-128	429.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158535_k127_1867932_0	1229780.BN381_250012	9.316e-150	484.0	COG3464@1|root,COG3464@2|Bacteria,2I56J@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1903510_3	1449347.JQLN01000001_gene448	4.922e-06	59.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,2M17K@2063|Kitasatospora	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158535_k127_1903510_1	1150864.MILUP08_44311	5.748e-19	101.0	COG0515@1|root,COG0515@2|Bacteria,2IMGY@201174|Actinobacteria,4DFCK@85008|Micromonosporales	201174|Actinobacteria	KLT	Domain of unknown function (DUF4352)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
SRR25158535_k127_1903510_0	33898.JRHJ01000069_gene7008	6.36e-82	293.0	COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria	201174|Actinobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158535_k127_1903510_2	204669.Acid345_2864	2.355e-13	80.0	COG4914@1|root,COG4914@2|Bacteria,3Y7K0@57723|Acidobacteria,2JMQS@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1908715_2	497965.Cyan7822_5301	3.1e-84	285.0	COG0584@1|root,COG0584@2|Bacteria,1G106@1117|Cyanobacteria,3KFYP@43988|Cyanothece	1117|Cyanobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Alk_phosphatase,GDPD,HemolysinCabind,Phytase-like
SRR25158535_k127_1908715_0	365528.KB891252_gene5685	5.453e-118	393.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,4ESBP@85013|Frankiales	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158535_k127_1908715_1	1123024.AUII01000003_gene3402	3.295e-96	341.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4DYKD@85010|Pseudonocardiales	201174|Actinobacteria	GM	epimerase dehydratase	galE2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0501	Epimerase
SRR25158535_k127_1908715_3	269800.Tfu_0222	7.24e-72	258.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria,4EFY5@85012|Streptosporangiales	201174|Actinobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SRR25158535_k127_1908715_4	383372.Rcas_3580	2.821e-31	136.0	COG1664@1|root,COG1664@2|Bacteria,2G79N@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1908715_5	1278073.MYSTI_01695	0.0005067	45.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PZJ@68525|delta/epsilon subdivisions,2WMGB@28221|Deltaproteobacteria,2YVBK@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158535_k127_1908895_5	33876.JNXY01000035_gene666	4.8e-62	217.0	COG3358@1|root,COG3358@2|Bacteria,2IHE3@201174|Actinobacteria,4DCTC@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
SRR25158535_k127_1908895_4	1394178.AWOO02000017_gene6716	3.089e-63	233.0	COG0491@1|root,COG0491@2|Bacteria,2GMSA@201174|Actinobacteria,4EQ0T@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_1908895_9	1968.JOEV01000009_gene1713	8.507e-16	90.0	2DQ7G@1|root,3353J@2|Bacteria,2I354@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158535_k127_1908895_3	1237500.ANBA01000015_gene2223	6.223e-80	278.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158535_k127_1908895_2	263358.VAB18032_09350	5.974e-123	406.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DB0R@85008|Micromonosporales	201174|Actinobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
SRR25158535_k127_1908895_7	1123319.AUBE01000001_gene1851	2.578e-60	210.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_1908895_8	1463825.JNXC01000012_gene1908	4.53e-34	153.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria,4E5ET@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_1908895_1	1068978.AMETH_3555	1.994e-174	563.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DZGD@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_1908895_0	1210045.ALNP01000041_gene2850	1.485e-181	584.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158535_k127_1908895_6	298653.Franean1_1099	2.116e-61	214.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158535_k127_1915965_5	298653.Franean1_3414	3.157e-48	177.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR25158535_k127_1915965_7	1500304.JQKY01000007_gene3276	6.997e-40	163.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158535_k127_1915965_1	1123023.JIAI01000002_gene5036	7.218e-102	339.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_1915965_13	543632.JOJL01000011_gene6877	1.832e-07	57.0	2E4KR@1|root,32ZFQ@2|Bacteria,2II90@201174|Actinobacteria,4DDQY@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1915965_4	1206731.BAGB01000041_gene8786	1.994e-50	185.0	COG2259@1|root,31BQE@2|Bacteria,2IT5M@201174|Actinobacteria,4G99T@85025|Nocardiaceae	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SRR25158535_k127_1915965_11	926560.KE387023_gene2058	3.75e-13	74.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SRR25158535_k127_1915965_2	262316.MAP_2165	2.088e-70	247.0	COG2128@1|root,COG2128@2|Bacteria,2I829@201174|Actinobacteria,23511@1762|Mycobacteriaceae	201174|Actinobacteria	L	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158535_k127_1915965_9	570268.ANBB01000069_gene1507	4.311e-17	93.0	COG3039@1|root,COG3039@2|Bacteria,2GJQM@201174|Actinobacteria,4EMXP@85012|Streptosporangiales	201174|Actinobacteria	L	Cluster 0025 8 SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_1915965_3	1246445.ANAY01000084_gene2125	2.57e-69	244.0	COG3039@1|root,COG3039@2|Bacteria,2GJQM@201174|Actinobacteria	201174|Actinobacteria	L	Cluster 0025 8 SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_1915965_0	1206733.BAGC01000100_gene6188	7.217e-136	451.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4G1Y6@85025|Nocardiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR25158535_k127_1915965_12	1150399.AQYK01000002_gene3169	6.789e-10	68.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4FQT1@85023|Microbacteriaceae	201174|Actinobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158535_k127_1915965_10	1068978.AMETH_3053	2.912e-13	76.0	COG0716@1|root,COG0716@2|Bacteria,2IQZD@201174|Actinobacteria,4E5JA@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Flavodoxin	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_1,Flavodoxin_5
SRR25158535_k127_1915965_14	345341.KUTG_01783	0.0005504	49.0	COG0167@1|root,COG0167@2|Bacteria,2GNPJ@201174|Actinobacteria	201174|Actinobacteria	F	dihydroorotate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1915965_8	748727.CLJU_c32630	1.461e-18	95.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,36IJE@31979|Clostridiaceae	186801|Clostridia	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
SRR25158535_k127_1916014_5	1116232.AHBF01000118_gene4342	3.15e-11	68.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_1916014_6	1380370.JIBA01000011_gene3112	1.25e-09	68.0	2DRM0@1|root,33C8E@2|Bacteria,2GVJT@201174|Actinobacteria,4FHSM@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1916014_4	485913.Krac_2065	6.322e-59	217.0	COG3246@1|root,COG3246@2|Bacteria	2|Bacteria	K	L-lysine catabolic process to acetate	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
SRR25158535_k127_1916014_7	28042.GU90_14030	0.0001857	44.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4DXIV@85010|Pseudonocardiales	201174|Actinobacteria	CH	FAD binding domain	-	GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018669,GO:0019439,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.14.13.24	ko:K22270	ko00362,ko01120,map00362,map01120	-	R02589	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
SRR25158535_k127_1916014_1	1894.JOER01000057_gene3279	1.791e-123	421.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_1916014_0	1122182.KB903834_gene5922	1.297e-142	488.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D9UJ@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_1916014_2	37919.EP51_38655	3.055e-112	374.0	COG2207@1|root,COG2207@2|Bacteria,2GST6@201174|Actinobacteria,4FU1A@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SRR25158535_k127_1916014_3	37919.EP51_38660	1.228e-63	220.0	2DS2P@1|root,33E8J@2|Bacteria,2IT0P@201174|Actinobacteria,4G6UG@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
SRR25158535_k127_1919299_4	1121272.KB903249_gene2399	1.826e-126	429.0	COG0204@1|root,COG0204@2|Bacteria,2I8I4@201174|Actinobacteria,4D914@85008|Micromonosporales	201174|Actinobacteria	I	Glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SRR25158535_k127_1919299_5	479432.Sros_7395	3.252e-118	388.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4EHBT@85012|Streptosporangiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SRR25158535_k127_1919299_7	1906.SFRA_15780	7.285e-103	349.0	2CEY7@1|root,2Z8CG@2|Bacteria,2GKI0@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1919299_0	351607.Acel_1865	8.714e-293	913.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SRR25158535_k127_1919299_3	1298863.AUEP01000003_gene3116	8.127e-130	417.0	COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DNTD@85009|Propionibacteriales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
SRR25158535_k127_1919299_2	1380390.JIAT01000012_gene3163	7.232e-169	545.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CRJZ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K12429	-	-	-	-	ko00000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1919299_6	110319.CF8_0231	5.855e-107	363.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4DNTA@85009|Propionibacteriales	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
SRR25158535_k127_1919299_8	288705.RSal33209_2532	6.35e-31	133.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria,1W98D@1268|Micrococcaceae	201174|Actinobacteria	S	Transglycosylase-like domain	-	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	LysM,Transglycosylas
SRR25158535_k127_1919299_1	266117.Rxyl_2925	2.962e-243	762.0	COG1012@1|root,COG1012@2|Bacteria,2GT45@201174|Actinobacteria,4CPPU@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158535_k127_1919299_9	1108045.GORHZ_050_00090	1.073e-08	57.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria	201174|Actinobacteria	E	Bacterial transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep,Hexapep_2
SRR25158535_k127_1919818_4	485913.Krac_8704	2.538e-42	170.0	28I4Y@1|root,2Z88D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1919818_7	945550.VISI1226_03565	3.279e-11	76.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1XV48@135623|Vibrionales	135623|Vibrionales	O	COG1030 Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
SRR25158535_k127_1919818_3	1123321.KB905819_gene5903	9.205e-51	199.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158535_k127_1919818_1	1449347.JQLN01000005_gene4885	1.178e-93	346.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,2M1HD@2063|Kitasatospora	201174|Actinobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SRR25158535_k127_1919818_5	1356852.N008_20650	1.506e-39	162.0	COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,47PYQ@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
SRR25158535_k127_1919818_0	706434.HMPREF9429_00424	1.786e-101	363.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158535_k127_1919818_6	1158318.ATXC01000001_gene854	1.635e-25	111.0	COG1610@1|root,COG1610@2|Bacteria,2G4V2@200783|Aquificae	200783|Aquificae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SRR25158535_k127_1919818_2	1121017.AUFG01000019_gene2400	1.486e-63	231.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria,4FEHS@85021|Intrasporangiaceae	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158535_k127_192298_6	66429.JOFL01000011_gene2612	2.604e-07	52.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158535_k127_192298_0	1246995.AFR_12575	1.435e-154	507.0	COG1012@1|root,COG1012@2|Bacteria,2GMNB@201174|Actinobacteria	201174|Actinobacteria	C	Aldehyde dehydrogenase	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
SRR25158535_k127_192298_3	471853.Bcav_0314	1.491e-74	263.0	COG3970@1|root,COG3970@2|Bacteria,2GN7V@201174|Actinobacteria	201174|Actinobacteria	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
SRR25158535_k127_192298_5	1120949.KB903301_gene6278	1.133e-10	63.0	COG1073@1|root,COG1073@2|Bacteria,2I2V0@201174|Actinobacteria,4DCCQ@85008|Micromonosporales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SRR25158535_k127_192298_1	861299.J421_1634	5.812e-92	315.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_192298_4	1227500.C494_14668	1.761e-52	207.0	COG0642@1|root,arCOG02327@2157|Archaea,2XTH8@28890|Euryarchaeota,23S6Q@183963|Halobacteria	183963|Halobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,PAS_4
SRR25158535_k127_192298_2	1380347.JNII01000005_gene3031	1.172e-77	263.0	COG5634@1|root,COG5634@2|Bacteria,2GJRH@201174|Actinobacteria,4ETTV@85013|Frankiales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2278)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2278,LTD
SRR25158535_k127_1923871_3	1382356.JQMP01000003_gene1869	1.224e-71	254.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia	189775|Thermomicrobia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SRR25158535_k127_1923871_5	1122182.KB903833_gene5623	2.036e-11	76.0	2EI21@1|root,33BTI@2|Bacteria,2GZFC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1923871_1	405948.SACE_1365	3.076e-94	317.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4DXH8@85010|Pseudonocardiales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SRR25158535_k127_1923871_4	457570.Nther_2188	2.035e-68	253.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158535_k127_1923871_2	67352.JODS01000012_gene4386	5.361e-86	297.0	COG4195@1|root,COG4195@2|Bacteria,2IC6D@201174|Actinobacteria	201174|Actinobacteria	S	Poly-gamma-glutamate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Gamma_PGA_hydro
SRR25158535_k127_1923871_0	656024.FsymDg_4332	1.526e-107	356.0	COG2265@1|root,COG2265@2|Bacteria,2GK97@201174|Actinobacteria,4ESJB@85013|Frankiales	201174|Actinobacteria	J	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_15,Methyltransf_25
SRR25158535_k127_1924081_1	883078.HMPREF9695_00769	8.587e-204	647.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,2TRX7@28211|Alphaproteobacteria,3JW8K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Radical SAM superfamily	fbiC	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SRR25158535_k127_1924081_0	483219.LILAB_22120	3.228e-208	659.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2Z0QK@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158535_k127_1924081_2	45351.EDO47839	3.423e-139	466.0	COG0076@1|root,KOG1383@2759|Eukaryota,38BZ3@33154|Opisthokonta,3B9JG@33208|Metazoa	33208|Metazoa	E	sphinganine-1-phosphate aldolase activity	SGPL1	GO:0000003,GO:0001501,GO:0001553,GO:0001568,GO:0001570,GO:0001655,GO:0001667,GO:0001822,GO:0001944,GO:0002376,GO:0002520,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006672,GO:0006807,GO:0006915,GO:0006928,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007283,GO:0007525,GO:0007527,GO:0007548,GO:0008117,GO:0008150,GO:0008152,GO:0008202,GO:0008209,GO:0008210,GO:0008219,GO:0008406,GO:0008584,GO:0008585,GO:0008610,GO:0009056,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009791,GO:0009887,GO:0009987,GO:0010171,GO:0010761,GO:0010817,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016042,GO:0016477,GO:0016829,GO:0016830,GO:0016832,GO:0019752,GO:0019953,GO:0022414,GO:0022602,GO:0023052,GO:0030097,GO:0030148,GO:0030149,GO:0030154,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033327,GO:0034641,GO:0034754,GO:0035239,GO:0035295,GO:0040008,GO:0040011,GO:0040014,GO:0042175,GO:0042445,GO:0042698,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045137,GO:0046466,GO:0046467,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0048008,GO:0048232,GO:0048511,GO:0048513,GO:0048514,GO:0048534,GO:0048608,GO:0048609,GO:0048638,GO:0048705,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050830,GO:0050896,GO:0051179,GO:0051239,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0060021,GO:0060322,GO:0060323,GO:0060324,GO:0060325,GO:0061061,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072001,GO:0072358,GO:0072359,GO:0097190,GO:0098542,GO:0098827,GO:1901360,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	4.1.2.27	ko:K01634,ko:K20704	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	Pyridoxal_deC
SRR25158535_k127_1924081_3	1123371.ATXH01000003_gene1969	8.889e-14	72.0	COG1376@1|root,COG1376@2|Bacteria,2GGS7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
SRR25158535_k127_1924676_1	356851.JOAN01000035_gene1932	3.374e-37	146.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4DAQQ@85008|Micromonosporales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158535_k127_1924676_0	452652.KSE_15380	3.476e-281	887.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,2M2GY@2063|Kitasatospora	201174|Actinobacteria	GJM	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
SRR25158535_k127_1925658_2	908612.HMPREF9720_0348	1.237e-56	211.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,22U7E@171550|Rikenellaceae	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158535_k127_1925658_5	196162.Noca_3127	6.15e-16	80.0	2ES7R@1|root,33JSG@2|Bacteria,2IQ6C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1925658_4	1313172.YM304_19100	1.313e-17	97.0	COG3688@1|root,COG3688@2|Bacteria,2GR19@201174|Actinobacteria	201174|Actinobacteria	M	RNA-binding protein containing a PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158535_k127_1925658_6	47839.CCAU010000011_gene5596	0.000122	50.0	2EGHN@1|root,33A9R@2|Bacteria,2GSZ1@201174|Actinobacteria,23BB4@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1925658_3	66377.JOBH01000007_gene2063	1.415e-41	171.0	COG0308@1|root,COG0308@2|Bacteria,2GK29@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1925658_1	1449347.JQLN01000004_gene7135	1.642e-70	259.0	COG0501@1|root,COG0501@2|Bacteria,2GRBS@201174|Actinobacteria,2M1GP@2063|Kitasatospora	201174|Actinobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
SRR25158535_k127_1925658_0	471852.Tcur_3059	3.626e-87	314.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4EHII@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_1931523_0	653045.Strvi_1239	1.407e-80	279.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria	201174|Actinobacteria	L	Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_1931523_1	1382356.JQMP01000004_gene532	2.801e-63	225.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158535_k127_1931523_2	298653.Franean1_0255	1.139e-24	113.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158535_k127_1931953_2	326424.FRAAL6879	7.26e-41	164.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1931953_0	298655.KI912266_gene711	5.505e-147	495.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158535_k127_1931953_3	1340493.JNIF01000003_gene4568	7.025e-20	100.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K04786,ko:K12240,ko:K13613,ko:K15677	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	ADH_N,ADH_zinc_N,AMP-binding,Acyl_transf_1,Condensation,Glyoxalase_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,NUDIX,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158535_k127_1931953_1	1137268.AZXF01000039_gene973	2.049e-53	191.0	COG0463@1|root,COG0463@2|Bacteria,2I3HM@201174|Actinobacteria,4EG7U@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_1935403_4	640511.BC1002_5959	1.115e-103	351.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1935403_8	713587.THITH_05975	4.757e-49	179.0	COG5573@1|root,COG5573@2|Bacteria,1RKIK@1224|Proteobacteria,1SBYM@1236|Gammaproteobacteria,1WZ8S@135613|Chromatiales	135613|Chromatiales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158535_k127_1935403_9	266117.Rxyl_0142	8.343e-40	171.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4CQIW@84995|Rubrobacteria	84995|Rubrobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
SRR25158535_k127_1935403_12	222984.JNCS01000001_gene1984	2.989e-29	131.0	COG0477@1|root,arCOG00134@2157|Archaea,2Y8EE@28890|Euryarchaeota,2419Q@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1935403_6	1172188.KB911822_gene932	1.642e-83	291.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4FI2F@85021|Intrasporangiaceae	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB,Oxidored_molyb
SRR25158535_k127_1935403_7	266117.Rxyl_1776	8.826e-69	247.0	COG1707@1|root,COG1707@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	ACT
SRR25158535_k127_1935403_13	83332.Rv0229c	2.15e-26	123.0	COG1487@1|root,COG1487@2|Bacteria,2IRPF@201174|Actinobacteria,23F4G@1762|Mycobacteriaceae	201174|Actinobacteria	S	toxic component of a	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158535_k127_1935403_0	485913.Krac_2635	3.445e-263	842.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
SRR25158535_k127_1935403_2	485913.Krac_2637	3.666e-175	568.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158535_k127_1935403_11	485913.Krac_2638	3.194e-30	123.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158535_k127_1935403_10	1177594.MIC448_2190008	4.797e-31	131.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K03090,ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SRR25158535_k127_1935403_1	1380390.JIAT01000016_gene5527	4.246e-186	591.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_1935403_14	1054860.KB913030_gene4123	2.087e-16	84.0	2B42Y@1|root,31WTH@2|Bacteria,2INUX@201174|Actinobacteria	201174|Actinobacteria	S	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
SRR25158535_k127_1935403_3	749414.SBI_00971	3.472e-153	491.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_1940415_1	526225.Gobs_3881	3.202e-83	297.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4ETFG@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SRR25158535_k127_1940415_4	1223544.GSI01S_15_00860	2.322e-23	106.0	COG3631@1|root,COG3631@2|Bacteria,2HTXE@201174|Actinobacteria,4GGPN@85026|Gordoniaceae	201174|Actinobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1940415_0	391037.Sare_0041	6.038e-84	286.0	COG1396@1|root,COG1396@2|Bacteria,2GJBK@201174|Actinobacteria,4D91Z@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_1940415_5	469371.Tbis_0235	3.745e-19	98.0	2E6IT@1|root,3315W@2|Bacteria,2HP20@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR25158535_k127_1940415_2	483219.LILAB_04905	8.246e-75	269.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Membrane-bound serine protease (ClpP class)	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
SRR25158535_k127_1940415_3	1121877.JQKF01000003_gene1489	4.431e-36	140.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CMZ4@84992|Acidimicrobiia	84992|Acidimicrobiia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SRR25158535_k127_1943748_1	319795.Dgeo_2503	3.728e-15	89.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	-	2.1.1.45,2.7.4.9	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02094,R02098,R02101	RC00002,RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SRR25158535_k127_1943748_0	883103.HMPREF9703_00680	1.117e-24	112.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,27FNN@186828|Carnobacteriaceae	91061|Bacilli	T	helix_turn_helix, Lux Regulon	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_1950285_2	1123368.AUIS01000001_gene1960	9.371e-128	417.0	COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,1RZGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_1950285_0	1120936.KB907226_gene2801	7.647e-162	526.0	COG0028@1|root,COG0028@2|Bacteria,2GJ20@201174|Actinobacteria,4EH3P@85012|Streptosporangiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_1950285_3	136273.GY22_06300	8.381e-64	224.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,1WAU3@1268|Micrococcaceae	201174|Actinobacteria	S	Dak2	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158535_k127_1950285_1	1380390.JIAT01000010_gene4298	2.143e-148	476.0	COG2376@1|root,COG2376@2|Bacteria,2GJV9@201174|Actinobacteria,4CPK7@84995|Rubrobacteria	84995|Rubrobacteria	G	Dihydroxyacetone kinase DhaK, subunit	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
SRR25158535_k127_1950285_4	592015.HMPREF1705_01771	4.535e-52	186.0	COG0554@1|root,COG0554@2|Bacteria,3TABB@508458|Synergistetes	508458|Synergistetes	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SRR25158535_k127_1957001_0	345341.KUTG_07540	1.445e-116	391.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria,4EAUY@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158535_k127_1957494_3	1068978.AMETH_3021	1.226e-07	63.0	2BBFR@1|root,324Z0@2|Bacteria,2HI9R@201174|Actinobacteria,4DXCU@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1957494_2	1184609.KILIM_052_00250	2.099e-18	94.0	COG0784@1|root,COG0784@2|Bacteria,2II71@201174|Actinobacteria,4F6ZE@85018|Dermatophilaceae	201174|Actinobacteria	T	cheY-homologous receiver domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_1957494_0	1463854.JOHT01000001_gene2717	4.157e-63	225.0	2AXQV@1|root,31PRS@2|Bacteria,2I93X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158535_k127_1957494_1	1150864.MILUP08_41899	4.531e-21	103.0	2F90D@1|root,341C4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_1961689_0	644283.Micau_0984	5.979e-232	724.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DBSB@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_1963485_3	543632.JOJL01000020_gene684	1.285e-102	349.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2IAS1@201174|Actinobacteria,4D9ME@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
SRR25158535_k127_1963485_1	479434.Sthe_2024	1.495e-179	574.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia	189775|Thermomicrobia	E	Cysteine synthase	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_1963485_0	1121346.KB899837_gene1264	1.139e-184	592.0	COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli,26ZHD@186822|Paenibacillaceae	91061|Bacilli	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158535_k127_1963485_5	500153.JOEK01000001_gene4199	3.384e-30	120.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_1963485_4	653045.Strvi_0509	2.22e-53	192.0	COG1510@1|root,COG1510@2|Bacteria,2GNYV@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158535_k127_1963485_2	1128421.JAGA01000002_gene1751	2.463e-140	456.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158535_k127_1978385_1	1043205.AFYF01000065_gene2189	2.943e-16	92.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4FGUA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_1978385_0	243274.THEMA_05515	2.173e-94	321.0	COG2008@1|root,COG2008@2|Bacteria,2GCFA@200918|Thermotogae	200918|Thermotogae	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	iLJ478.TM1744	Beta_elim_lyase
SRR25158535_k127_1978385_2	1459636.NTE_02809	3.812e-06	51.0	COG1915@1|root,arCOG04422@2157|Archaea,41SBQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
SRR25158535_k127_1979674_3	298655.KI912267_gene6800	1.251e-13	71.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_1979674_1	1111479.AXAR01000006_gene784	5.19e-194	618.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli,2782N@186823|Alicyclobacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
SRR25158535_k127_1979674_0	1125863.JAFN01000001_gene2057	6.019e-213	675.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_1979674_2	1211815.CBYP010000062_gene3157	1.767e-124	404.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4ERFZ@85013|Frankiales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SRR25158535_k127_1987929_5	1370120.AUWR01000011_gene1084	7.259e-20	89.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,233XN@1762|Mycobacteriaceae	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158535_k127_1987929_2	351607.Acel_0305	1.294e-52	188.0	COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4ESVR@85013|Frankiales	201174|Actinobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SRR25158535_k127_1987929_0	500153.JOEK01000005_gene2106	1.904e-92	309.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SRR25158535_k127_1987929_1	767029.HMPREF9154_2275	1.105e-60	227.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4DN59@85009|Propionibacteriales	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SRR25158535_k127_1987929_4	656024.FsymDg_3959	1.285e-31	125.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4ET1Y@85013|Frankiales	201174|Actinobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SRR25158535_k127_1987929_3	1246995.AFR_04520	8.543e-38	143.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4DAJD@85008|Micromonosporales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158535_k127_1991050_0	671143.DAMO_1539	3.635e-117	394.0	COG0463@1|root,COG0463@2|Bacteria,2NQD9@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
SRR25158535_k127_1991050_2	1033737.CAEV01000061_gene2883	1.402e-09	71.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,36ESU@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158535_k127_1991050_1	266940.Krad_0432	5.162e-67	235.0	COG1408@1|root,COG1408@2|Bacteria,2GJHT@201174|Actinobacteria	201174|Actinobacteria	S	metallophosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SRR25158535_k127_1992261_0	1122138.AQUZ01000018_gene7529	1.66e-126	420.0	COG3385@1|root,COG3385@2|Bacteria,2GJUG@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158535_k127_1992261_1	675635.Psed_0888	2.75e-22	98.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria,4EAUY@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158535_k127_1997332_5	35754.JNYJ01000079_gene4339	1.09e-35	138.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,4DCCB@85008|Micromonosporales	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
SRR25158535_k127_1997332_4	298654.FraEuI1c_2660	1.352e-55	203.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4EVGQ@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0014)	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
SRR25158535_k127_1997332_0	595537.Varpa_4335	5.598e-132	443.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VK5J@28216|Betaproteobacteria,4AADF@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the 5'-nucleotidase family	ushA	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
SRR25158535_k127_1997332_1	1957.JODX01000004_gene3112	2.153e-90	310.0	COG0701@1|root,COG0701@2|Bacteria,2GJQ0@201174|Actinobacteria	201174|Actinobacteria	P	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
SRR25158535_k127_1997332_3	710111.FraQA3DRAFT_4003	7.333e-67	232.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1997332_2	298653.Franean1_1280	6.924e-81	274.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_1997332_6	1206731.BAGB01000041_gene8535	7.021e-15	83.0	COG3689@1|root,COG3689@2|Bacteria,2GNFK@201174|Actinobacteria,4G0HA@85025|Nocardiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1980
SRR25158535_k127_2000400_6	935839.JAGJ01000020_gene118	2.321e-45	177.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4F3B4@85017|Promicromonosporaceae	201174|Actinobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	GO:0008150,GO:0040007	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
SRR25158535_k127_2000400_4	58123.JOFJ01000002_gene2539	2.117e-64	235.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4EH9B@85012|Streptosporangiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
SRR25158535_k127_2000400_10	861299.J421_1276	2.284e-07	61.0	COG3794@1|root,COG3794@2|Bacteria,1ZTTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
SRR25158535_k127_2000400_8	1120949.KB903315_gene148	2.693e-31	126.0	COG1695@1|root,COG1695@2|Bacteria,2GRVH@201174|Actinobacteria,4DJQ9@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_2000400_11	1380390.JIAT01000010_gene4657	0.0001751	54.0	COG4454@1|root,COG4454@2|Bacteria,2I7WC@201174|Actinobacteria,4CTCK@84995|Rubrobacteria	84995|Rubrobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158535_k127_2000400_1	604354.TSIB_0224	1.347e-128	422.0	COG0162@1|root,arCOG01886@2157|Archaea,2XTA0@28890|Euryarchaeota,242Y2@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
SRR25158535_k127_2000400_5	1869.MB27_32655	8.693e-55	196.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,4DA1M@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the UPF0234 family	trpF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
SRR25158535_k127_2000400_7	861299.J421_2147	1.982e-36	144.0	COG3795@1|root,COG3795@2|Bacteria,1ZV0M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_2000400_0	1160718.SU9_27504	8.684e-148	484.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2000400_2	525904.Tter_2663	5.527e-113	376.0	COG2059@1|root,COG2059@2|Bacteria,2NPUT@2323|unclassified Bacteria	2|Bacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_2000400_3	1121946.AUAX01000005_gene5226	3.862e-97	328.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4DATY@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SRR25158535_k127_2000400_9	1150864.MILUP08_40248	5.416e-24	109.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4D9RX@85008|Micromonosporales	201174|Actinobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158535_k127_2016200_1	656024.FsymDg_4531	4.61e-99	330.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4ERYP@85013|Frankiales	201174|Actinobacteria	I	PFAM Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158535_k127_2016200_2	467200.ACFA01000473_gene3988	6.258e-44	167.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158535_k127_2016200_4	58123.JOFJ01000002_gene2352	4.231e-32	128.0	2CQNK@1|root,32SMG@2|Bacteria,2IIJ7@201174|Actinobacteria	201174|Actinobacteria	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
SRR25158535_k127_2016200_0	888060.HMPREF9081_1352	3.374e-111	389.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158535_k127_2016200_3	266117.Rxyl_1043	6.404e-34	153.0	COG5650@1|root,COG5650@2|Bacteria,2HYCN@201174|Actinobacteria,4CQKH@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158535_k127_2016200_5	477641.MODMU_5568	0.0003006	46.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4ET1A@85013|Frankiales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
SRR25158535_k127_2018672_2	1214101.BN159_0146	9.648e-42	157.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria	201174|Actinobacteria	L	resolvase	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
SRR25158535_k127_2018672_3	479432.Sros_6673	1.551e-08	67.0	2EIHP@1|root,33C91@2|Bacteria,2ICMY@201174|Actinobacteria,4EH8I@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
SRR25158535_k127_2018672_0	28444.JODQ01000007_gene5527	1.782e-149	502.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria,4EFIV@85012|Streptosporangiales	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,DUF1116,Ligase_CoA
SRR25158535_k127_2018672_1	1123023.JIAI01000024_gene4242	8.155e-80	278.0	COG0074@1|root,COG0074@2|Bacteria,2GN20@201174|Actinobacteria,4E87Z@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
SRR25158535_k127_2023677_0	1382306.JNIM01000001_gene1083	1.993e-306	985.0	COG1674@1|root,COG1674@2|Bacteria,2G5Y3@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
SRR25158535_k127_2023677_1	589865.DaAHT2_1882	3.413e-21	98.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria,2MKTS@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SRR25158535_k127_2023677_2	1122609.AUGT01000022_gene710	2.106e-11	71.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4DN47@85009|Propionibacteriales	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
SRR25158535_k127_2025594_0	1463825.JNXC01000050_gene7411	1.817e-311	964.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4E234@85010|Pseudonocardiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	ko:K12436	-	-	-	-	ko00000,ko01004	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,Acyl_transf_1,Docking,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
SRR25158535_k127_202987_4	338966.Ppro_2543	1.447e-41	156.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
SRR25158535_k127_202987_3	1122919.KB905560_gene1486	4.511e-47	186.0	COG0030@1|root,COG0030@2|Bacteria,1UY9S@1239|Firmicutes,4IRC2@91061|Bacilli,276QC@186822|Paenibacillaceae	91061|Bacilli	J	Ribosomal RNA adenine dimethylases	-	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
SRR25158535_k127_202987_5	1380390.JIAT01000010_gene4305	1.017e-36	145.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CQIK@84995|Rubrobacteria	84995|Rubrobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SRR25158535_k127_202987_1	1380390.JIAT01000010_gene4306	2.353e-83	289.0	COG0451@1|root,COG0451@2|Bacteria,2GN90@201174|Actinobacteria,4CRU1@84995|Rubrobacteria	84995|Rubrobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158535_k127_202987_0	765420.OSCT_2314	6.491e-137	469.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi,3750F@32061|Chloroflexia	32061|Chloroflexia	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
SRR25158535_k127_202987_2	1380390.JIAT01000010_gene4302	2.666e-64	251.0	COG3075@1|root,COG3075@2|Bacteria,2GMNS@201174|Actinobacteria	201174|Actinobacteria	E	Glycerol-3-phosphate dehydrogenase	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
SRR25158535_k127_202987_6	357808.RoseRS_3301	2.204e-11	77.0	COG0247@1|root,COG0247@2|Bacteria,2G7VD@200795|Chloroflexi,3754W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
SRR25158535_k127_2033582_0	58123.JOFJ01000012_gene5324	3.51e-195	618.0	COG1505@1|root,COG1505@2|Bacteria,2IRXB@201174|Actinobacteria,4EG49@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SRR25158535_k127_2033582_1	1193181.BN10_860014	1.523e-71	252.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4FEEI@85021|Intrasporangiaceae	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SRR25158535_k127_2033582_2	1382306.JNIM01000001_gene2651	4.882e-66	229.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_2038502_3	1246995.AFR_10110	3e-79	287.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4DAAT@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158535_k127_2038502_1	656024.FsymDg_2502	1.264e-120	402.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4ERSZ@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
SRR25158535_k127_2038502_8	1123320.KB889675_gene3832	1.734e-41	167.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
SRR25158535_k127_2038502_7	298654.FraEuI1c_3195	1.082e-43	173.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158535_k127_2038502_5	1380394.JADL01000007_gene4518	1.483e-57	219.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2U3WT@28211|Alphaproteobacteria,2JZEP@204441|Rhodospirillales	204441|Rhodospirillales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158535_k127_2038502_4	1380390.JIAT01000009_gene576	1.384e-58	221.0	COG1522@1|root,COG1522@2|Bacteria,2IFSQ@201174|Actinobacteria,4CSWD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158535_k127_2038502_2	369723.Strop_2274	7.403e-99	340.0	COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4DBJZ@85008|Micromonosporales	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K11939	-	-	-	-	ko00000,ko02000	2.A.7.3.6	-	-	EamA
SRR25158535_k127_2038502_6	561175.KB894104_gene1126	1.849e-46	185.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SRR25158535_k127_2038502_0	351607.Acel_1054	0.0	1202.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERD2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158535_k127_2038862_0	1380393.JHVP01000005_gene3550	5.895e-162	519.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158535_k127_2038862_1	1122182.KB903833_gene5401	1.965e-145	507.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158535_k127_2038862_2	1123023.JIAI01000001_gene6048	3.876e-140	458.0	arCOG11292@1|root,309SY@2|Bacteria,2GTQ8@201174|Actinobacteria,4E8RX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2038862_3	1380356.JNIK01000017_gene2798	1.956e-26	116.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4ESTX@85013|Frankiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158535_k127_2042010_5	1500304.JQKY01000007_gene3276	3.227e-43	173.0	COG2114@1|root,COG2114@2|Bacteria,1Q8YH@1224|Proteobacteria,2VD35@28211|Alphaproteobacteria,4BA5X@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
SRR25158535_k127_2042010_3	471853.Bcav_3419	1.565e-69	248.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria	201174|Actinobacteria	KT	transcriptional	glnR	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SRR25158535_k127_2042010_9	1136417.AZWE01000031_gene4786	3.27e-13	83.0	COG1977@1|root,COG1977@2|Bacteria,2IQIT@201174|Actinobacteria,4DFX3@85008|Micromonosporales	201174|Actinobacteria	H	ThiS family	moaD2	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SRR25158535_k127_2042010_10	463191.SSEG_02494	5.614e-11	74.0	2AQTN@1|root,31G1R@2|Bacteria,2IACN@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2993
SRR25158535_k127_2042010_6	1033730.CAHG01000008_gene3199	6.634e-36	149.0	COG0404@1|root,COG0404@2|Bacteria,2I4ER@201174|Actinobacteria,4DX1V@85009|Propionibacteriales	201174|Actinobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SRR25158535_k127_2042010_4	1179773.BN6_18760	1.209e-63	231.0	COG4448@1|root,COG4448@2|Bacteria,2GJA7@201174|Actinobacteria,4DYR1@85010|Pseudonocardiales	201174|Actinobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
SRR25158535_k127_2042010_7	1223523.H340_21281	1.478e-32	144.0	COG1396@1|root,COG1396@2|Bacteria,2IKVI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
SRR25158535_k127_2042010_11	1123320.KB889669_gene3186	2.067e-08	60.0	2ED1B@1|root,336YA@2|Bacteria,2GQRF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2042010_1	1114959.SZMC14600_13769	1.916e-122	407.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4DX7I@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway	mshA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2042010_8	326424.FRAAL0949	7.069e-28	119.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria,4ESU9@85013|Frankiales	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
SRR25158535_k127_2042010_0	208444.JNYY01000001_gene5720	3.427e-145	471.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria,4E72B@85010|Pseudonocardiales	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
SRR25158535_k127_2042010_2	706587.Desti_0471	2.118e-82	284.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria,2MQUJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158535_k127_2042010_13	1068980.ARVW01000001_gene1413	0.0001619	53.0	2E534@1|root,32ZWA@2|Bacteria,2I9VJ@201174|Actinobacteria,4E5BX@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2637)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2637
SRR25158535_k127_2042918_1	1229780.BN381_130380	4.213e-66	254.0	COG4924@1|root,COG4924@2|Bacteria,2GNHY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
SRR25158535_k127_2042918_0	1229780.BN381_130379	6.646e-69	255.0	COG1196@1|root,COG1196@2|Bacteria,2GK6F@201174|Actinobacteria	201174|Actinobacteria	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
SRR25158535_k127_2045085_2	656519.Halsa_1971	7.245e-07	51.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,24MPT@186801|Clostridia,3WBTT@53433|Halanaerobiales	186801|Clostridia	J	PFAM S1 RNA binding domain	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
SRR25158535_k127_2045085_1	471857.Svir_32240	4.063e-08	66.0	COG2919@1|root,COG2919@2|Bacteria,2GQH7@201174|Actinobacteria,4E5EA@85010|Pseudonocardiales	201174|Actinobacteria	D	Septum formation initiator	divIC	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
SRR25158535_k127_2045085_0	1121380.JNIW01000014_gene2484	5.989e-180	573.0	COG0148@1|root,COG0148@2|Bacteria,1WIST@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158535_k127_2048763_0	1313172.YM304_19720	1.973e-183	586.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CMTQ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
SRR25158535_k127_2058103_0	882086.SacxiDRAFT_2564	1.774e-236	744.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4DX7E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SRR25158535_k127_2058103_1	1380390.JIAT01000011_gene2750	7.89e-60	220.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4CRFT@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA
SRR25158535_k127_2058103_2	929712.KI912613_gene1735	1.98e-11	76.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CS29@84995|Rubrobacteria	84995|Rubrobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_2059752_0	298653.Franean1_1082	7.584e-219	698.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4ES5B@85013|Frankiales	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
SRR25158535_k127_2060576_2	1116232.AHBF01000018_gene3751	6.774e-60	210.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158535_k127_2060576_3	1463900.JOIX01000002_gene5233	1.56e-11	71.0	COG4747@1|root,COG4747@2|Bacteria,2GWF3@201174|Actinobacteria	201174|Actinobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2060576_1	485913.Krac_2351	1.149e-71	257.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SRR25158535_k127_2060576_0	471857.Svir_31520	1.562e-137	451.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4DYE8@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158535_k127_2060818_1	1120949.KB903294_gene4277	4.688e-42	169.0	COG1874@1|root,COG3828@1|root,COG1874@2|Bacteria,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria,4DCKN@85008|Micromonosporales	201174|Actinobacteria	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2,ThuA
SRR25158535_k127_2060818_0	1449353.JQMQ01000005_gene1304	8.614e-70	246.0	COG0697@1|root,COG0697@2|Bacteria,2GMPU@201174|Actinobacteria,2NM79@228398|Streptacidiphilus	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_2062701_0	47839.CCAU010000009_gene1461	3.951e-191	611.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,23407@1762|Mycobacteriaceae	201174|Actinobacteria	O	assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158535_k127_2062701_1	1449068.JMLQ01000003_gene2289	4.307e-15	77.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4FVJ8@85025|Nocardiaceae	201174|Actinobacteria	K	Winged helix-turn-helix DNA-binding	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
SRR25158535_k127_2063620_1	745310.G432_00775	1.898e-06	59.0	COG0477@1|root,COG2814@2|Bacteria,1NAK9@1224|Proteobacteria,2UHZU@28211|Alphaproteobacteria,2K2IR@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Sugar (and other) transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1
SRR25158535_k127_2063620_0	1276920.ADIAG_03996	1.183e-21	106.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,1W8QV@1268|Micrococcaceae	201174|Actinobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
SRR25158535_k127_206905_0	448385.sce1562	1.361e-227	715.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,42Z4I@68525|delta/epsilon subdivisions,2WUEY@28221|Deltaproteobacteria,2YW9D@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158535_k127_206905_1	1108045.GORHZ_158_00030	4.486e-147	475.0	COG5421@1|root,COG5421@2|Bacteria,2GPCI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_2080533_2	1449976.KALB_2157	9.483e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4E2HU@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SRR25158535_k127_2080533_0	2074.JNYD01000038_gene513	1.709e-50	190.0	COG1082@1|root,COG1082@2|Bacteria,2GJ6E@201174|Actinobacteria,4DX95@85010|Pseudonocardiales	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
SRR25158535_k127_2080533_1	926569.ANT_02430	3.732e-12	73.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2085127_3	1283299.AUKG01000002_gene4242	1.809e-14	76.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4CPZC@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
SRR25158535_k127_2085127_0	1047013.AQSP01000140_gene2513	7.074e-57	214.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SRR25158535_k127_2085127_2	1003195.SCAT_4024	1.977e-17	87.0	2E3M2@1|root,32YJA@2|Bacteria,2GQQW@201174|Actinobacteria	201174|Actinobacteria	S	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
SRR25158535_k127_2085127_5	1133850.SHJG_0222	0.0008302	46.0	COG3631@1|root,COG3631@2|Bacteria,2GZ5Q@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158535_k127_2085127_1	1267534.KB906755_gene4719	2.235e-18	94.0	COG0607@1|root,COG0607@2|Bacteria,3Y8E7@57723|Acidobacteria,2JNGA@204432|Acidobacteriia	204432|Acidobacteriia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158535_k127_2085127_4	1120954.ATXE01000002_gene1187	2.276e-12	76.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DNNT@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SRR25158535_k127_2087432_0	1089545.KB913037_gene3547	1.337e-180	580.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria,4E98F@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR25158535_k127_2089818_0	471852.Tcur_2334	2.653e-120	408.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4EHUD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2089818_2	298654.FraEuI1c_2154	2.286e-69	249.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS,Methyltransf_11,Methyltransf_25
SRR25158535_k127_2089818_3	234267.Acid_2001	1.973e-31	138.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158535_k127_2089818_1	1386089.N865_03215	4.821e-72	246.0	COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4FEI2@85021|Intrasporangiaceae	201174|Actinobacteria	F	Nitrate reductase	rutG	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
SRR25158535_k127_2093361_1	1206730.BAGA01000184_gene3108	1.845e-97	329.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4FVK3@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SRR25158535_k127_2093361_6	649638.Trad_1394	1.267e-20	93.0	COG3905@1|root,COG3905@2|Bacteria	2|Bacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	vapB43	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	RHH_1
SRR25158535_k127_2093361_4	870187.Thini_1711	2.145e-53	191.0	COG1848@1|root,COG1848@2|Bacteria,1N8VX@1224|Proteobacteria,1SP0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158535_k127_2093361_2	1223523.H340_11245	2.317e-78	266.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
SRR25158535_k127_2093361_5	1120936.KB907225_gene2694	3.402e-23	113.0	COG3695@1|root,COG3695@2|Bacteria,2GQMD@201174|Actinobacteria,4EKN0@85012|Streptosporangiales	201174|Actinobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
SRR25158535_k127_2093361_0	1123023.JIAI01000001_gene6153	7.669e-132	431.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DYYS@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_2093361_7	211114.JOEF01000048_gene5356	4.489e-17	87.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4DYYS@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_2093361_3	330084.JNYZ01000050_gene8591	2.654e-58	211.0	COG0160@1|root,COG0160@2|Bacteria,2GKVH@201174|Actinobacteria,4DZMQ@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_2102141_0	525904.Tter_2125	6.905e-268	840.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2NQGX@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SRR25158535_k127_2102141_1	345341.KUTG_08818	1.033e-32	133.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DXFV@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pkaI	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158535_k127_2103965_3	1246995.AFR_12160	1.155e-05	48.0	COG3293@1|root,COG3293@2|Bacteria,2IIMK@201174|Actinobacteria,4DM68@85008|Micromonosporales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
SRR25158535_k127_2103965_1	285535.JOEY01000064_gene7599	2.627e-62	222.0	COG1609@1|root,COG1609@2|Bacteria,2GK7G@201174|Actinobacteria	201174|Actinobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
SRR25158535_k127_2103965_0	269800.Tfu_2490	0.0	1080.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4EGCZ@85012|Streptosporangiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SRR25158535_k127_2103965_2	326424.FRAAL1307	3.179e-06	53.0	2DPN9@1|root,332RH@2|Bacteria,2GXBG@201174|Actinobacteria,4EX96@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2108960_4	1122138.AQUZ01000035_gene6467	4.266e-45	174.0	COG0697@1|root,COG0697@2|Bacteria,2GS88@201174|Actinobacteria,4DTGN@85009|Propionibacteriales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_2108960_7	1120936.KB907208_gene983	1.464e-41	175.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4EHRX@85012|Streptosporangiales	201174|Actinobacteria	EK	Aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158535_k127_2108960_1	58123.JOFJ01000004_gene1639	3.302e-102	343.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4EHRX@85012|Streptosporangiales	201174|Actinobacteria	EK	Aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158535_k127_2108960_2	1501230.ET33_24170	4.604e-61	222.0	COG1309@1|root,COG1309@2|Bacteria,1VHN0@1239|Firmicutes,4HNH8@91061|Bacilli,26VSH@186822|Paenibacillaceae	91061|Bacilli	K	TetR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2108960_0	1206731.BAGB01000023_gene1222	4.81e-115	389.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4G5I0@85025|Nocardiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_2108960_5	1246995.AFR_19880	5.312e-44	166.0	COG0477@1|root,COG2814@2|Bacteria,2H4H5@201174|Actinobacteria,4DABJ@85008|Micromonosporales	201174|Actinobacteria	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_2108960_11	926554.KI912633_gene3916	1.27e-09	64.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158535_k127_2108960_10	546414.Deide_17330	3.52e-20	98.0	arCOG10517@1|root,31Y5Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2108960_8	1120950.KB892708_gene4220	5.396e-37	161.0	arCOG10517@1|root,31Y5Z@2|Bacteria,2IN0B@201174|Actinobacteria,4DV9U@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2108960_9	649831.L083_6770	2.349e-20	102.0	2DPJ9@1|root,332BI@2|Bacteria,2IGJC@201174|Actinobacteria,4DDAT@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158535_k127_2108960_3	208444.JNYY01000001_gene4896	8.094e-48	189.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4E51P@85010|Pseudonocardiales	201174|Actinobacteria	M	Sortase (surface protein transpeptidase)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397,Sortase
SRR25158535_k127_2108960_6	2002.JOEQ01000006_gene1493	1.502e-42	164.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_2119278_0	269800.Tfu_2017	3.97e-105	345.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4EFSC@85012|Streptosporangiales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158535_k127_2119278_3	1123258.AQXZ01000018_gene1232	1.802e-45	186.0	COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4FVEN@85025|Nocardiaceae	201174|Actinobacteria	K	May be required for sporulation	whiA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
SRR25158535_k127_2119278_2	1120934.KB894438_gene4953	5.747e-68	252.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,4DZS2@85010|Pseudonocardiales	201174|Actinobacteria	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
SRR25158535_k127_2119278_1	471852.Tcur_2195	9.544e-90	302.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4EGVC@85012|Streptosporangiales	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158535_k127_2135650_1	1089546.AQUI01000002_gene1930	1.682e-11	74.0	2EFG7@1|root,3398W@2|Bacteria	2|Bacteria	L	Recombination endonuclease VII	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_7
SRR25158535_k127_2135650_0	351607.Acel_1233	1.211e-142	466.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4ERXN@85013|Frankiales	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
SRR25158535_k127_2141638_2	246196.MSMEI_6095	5.536e-60	214.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,23547@1762|Mycobacteriaceae	201174|Actinobacteria	E	Belongs to the aspartokinase family	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158535_k127_2141638_1	1157637.KB892093_gene6817	2.854e-99	330.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
SRR25158535_k127_2141638_3	1444306.JFZC01000101_gene1275	1.973e-28	117.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26NYU@186821|Sporolactobacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
SRR25158535_k127_2141638_0	635013.TherJR_0068	1.926e-106	369.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,2602Z@186807|Peptococcaceae	186801|Clostridia	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SRR25158535_k127_2147534_3	1173024.KI912149_gene5179	8.898e-24	100.0	COG1743@1|root,COG1743@2|Bacteria,1G2KT@1117|Cyanobacteria	1117|Cyanobacteria	L	Adenine-specific DNA methylase containing a Zn-ribbon	-	-	-	ko:K07445	-	-	-	-	ko00000	-	-	-	DUF1156
SRR25158535_k127_2147534_2	365528.KB891181_gene4670	7.168e-28	119.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4ET6R@85013|Frankiales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
SRR25158535_k127_2147534_5	1048339.KB913029_gene5102	1.868e-06	61.0	COG3147@1|root,COG3147@2|Bacteria,2HC8A@201174|Actinobacteria,4EVYP@85013|Frankiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2147534_0	1463858.JOHR01000002_gene6089	2.25e-85	317.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SRR25158535_k127_2147534_1	1211815.CBYP010000044_gene361	1.884e-32	129.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4ET3Z@85013|Frankiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB2	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158535_k127_2147534_4	316274.Haur_3860	5.211e-23	107.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2147534_6	1348663.KCH_43720	0.0005921	45.0	COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,2M4T1@2063|Kitasatospora	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158535_k127_2159684_15	1227261.HMPREF0043_01664	3.198e-08	66.0	COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4D3AW@85005|Actinomycetales	201174|Actinobacteria	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2159684_6	365528.KB891159_gene5385	5.68e-101	346.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4ERHJ@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2159684_1	656024.FsymDg_1051	5.208e-154	502.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4ET5X@85013|Frankiales	201174|Actinobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
SRR25158535_k127_2159684_5	298654.FraEuI1c_6091	5.066e-106	370.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4EUCZ@85013|Frankiales	201174|Actinobacteria	GM	ABC transporter	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
SRR25158535_k127_2159684_12	1499968.TCA2_5950	1.943e-30	131.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,4HI7C@91061|Bacilli	91061|Bacilli	GM	Transport permease protein	rgpC	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_2159684_0	326424.FRAAL1236	3.717e-174	561.0	COG0438@1|root,COG0438@2|Bacteria,2IJ4J@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2159684_14	1340493.JNIF01000003_gene1962	2.535e-23	117.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SRR25158535_k127_2159684_8	452637.Oter_3708	1.303e-71	249.0	COG2227@1|root,COG2227@2|Bacteria,46VSV@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function (DUF1698)	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	-
SRR25158535_k127_2159684_4	561175.KB894100_gene4818	1.148e-115	383.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4EHEJ@85012|Streptosporangiales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	lytR2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158535_k127_2159684_2	479432.Sros_4198	1.014e-136	464.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4EJ1J@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158535_k127_2159684_7	1121472.AQWN01000005_gene2443	1.147e-80	278.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,261FK@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SRR25158535_k127_2159684_3	368407.Memar_0186	1.211e-127	417.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158535_k127_2159684_10	1101188.KI912155_gene941	2.274e-65	247.0	COG0346@1|root,COG0346@2|Bacteria,2HNYI@201174|Actinobacteria,1W95T@1268|Micrococcaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_2159684_11	351607.Acel_0412	2.151e-49	194.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4ESMP@85013|Frankiales	201174|Actinobacteria	K	TIGRFAM cell envelope-related function transcriptional attenuator	cpsA	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SRR25158535_k127_2159684_13	365528.KB891159_gene5374	5.022e-26	123.0	COG0365@1|root,COG0365@2|Bacteria,2I2IW@201174|Actinobacteria,4ET0W@85013|Frankiales	201174|Actinobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
SRR25158535_k127_2159684_9	1267535.KB906767_gene2669	4.826e-67	258.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria,3Y6IT@57723|Acidobacteria	57723|Acidobacteria	HM	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_12
SRR25158535_k127_2159684_16	1219045.BV98_003047	2.198e-07	55.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2159745_1	1343740.M271_23970	2.418e-102	339.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158535_k127_2159745_2	765420.OSCT_1705	1.549e-37	146.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,375U7@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SRR25158535_k127_2159745_3	935845.JADQ01000008_gene1835	3.302e-31	142.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SRR25158535_k127_2159745_0	405948.SACE_7208	3.305e-130	425.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4DYUX@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158535_k127_2160313_5	1229203.KI301992_gene1300	2.045e-48	194.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,3UW82@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158535_k127_2160313_0	710421.Mycch_2268	2.021e-136	453.0	COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,235R0@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	PFAM Lipopolysaccharide kinase (Kdo WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
SRR25158535_k127_2160313_3	1150864.MILUP08_45082	1.174e-56	205.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,4DB3G@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2160313_2	1123320.KB889675_gene3878	5.256e-96	326.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158535_k127_2160313_1	644283.Micau_4490	2.21e-128	424.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4D8ZI@85008|Micromonosporales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
SRR25158535_k127_2160313_4	756499.Desde_1767	1.403e-50	194.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,24G1K@186801|Clostridia,264CQ@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158535_k127_2160313_6	479432.Sros_2857	9.251e-18	91.0	2E49S@1|root,32RRE@2|Bacteria,2I83P@201174|Actinobacteria,4ERB6@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
SRR25158535_k127_2160313_7	1246995.AFR_12160	6.434e-06	48.0	COG3293@1|root,COG3293@2|Bacteria,2IIMK@201174|Actinobacteria,4DM68@85008|Micromonosporales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
SRR25158535_k127_2161231_14	1121877.JQKF01000025_gene833	2.484e-09	59.0	2E3QT@1|root,31FNG@2|Bacteria,2HGTF@201174|Actinobacteria,4CNV3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2161231_12	29306.JOBE01000045_gene6127	2.653e-26	120.0	2DS0G@1|root,33DYY@2|Bacteria,2GKA4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2161231_13	436229.JOEH01000010_gene5248	1.238e-10	74.0	COG3266@1|root,COG3266@2|Bacteria,2GN4E@201174|Actinobacteria,2NHGE@228398|Streptacidiphilus	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2161231_4	298653.Franean1_7297	7.42e-86	302.0	28IJ8@1|root,2Z8K6@2|Bacteria,2GIV3@201174|Actinobacteria,4ET84@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EccE
SRR25158535_k127_2161231_6	710696.Intca_3110	4.63e-82	302.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria,4FEPS@85021|Intrasporangiaceae	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2161231_9	222534.KB893735_gene700	1.819e-59	235.0	COG3505@1|root,COG3505@2|Bacteria,2ISKK@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
SRR25158535_k127_2161231_2	929712.KI912613_gene833	6.992e-92	332.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4CSSU@84995|Rubrobacteria	84995|Rubrobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158535_k127_2161231_1	1122182.KB903839_gene1144	1.634e-199	631.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4D8YX@85008|Micromonosporales	201174|Actinobacteria	C	Malate dehydrogenase	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
SRR25158535_k127_2161231_5	42256.RradSPS_1857	2.456e-83	305.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158535_k127_2161231_0	644966.Tmar_1769	1.851e-200	634.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes	1239|Firmicutes	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
SRR25158535_k127_2161231_11	68260.JOAY01000003_gene4579	2.31e-37	158.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158535_k127_2161231_10	326424.FRAAL1876	4.375e-44	173.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158535_k127_2161231_3	485913.Krac_9428	8.781e-89	303.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2161231_7	1288079.AUKN01000009_gene1146	8.285e-82	287.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_2161231_8	1156844.KB891810_gene8084	1.638e-73	262.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_2167831_0	1146883.BLASA_1432	1.837e-137	449.0	COG3328@1|root,COG3328@2|Bacteria,2H9CR@201174|Actinobacteria	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158535_k127_2167831_1	525368.HMPREF0591_5630	1.099e-87	296.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_2170657_1	575540.Isop_1664	2.378e-17	91.0	2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2170657_0	561175.KB894098_gene5385	1.121e-79	280.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4EHRZ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158535_k127_2171083_2	1123024.AUII01000010_gene790	6.609e-08	57.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4E0UA@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfurtransferase	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158535_k127_2171083_0	644283.Micau_0066	5.67e-59	208.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4D8QA@85008|Micromonosporales	201174|Actinobacteria	P	Sulfurtransferase	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158535_k127_2171083_1	484019.THA_582	5.042e-21	94.0	COG1278@1|root,COG1278@2|Bacteria,2GDFN@200918|Thermotogae	200918|Thermotogae	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158535_k127_2171083_3	1122611.KB903939_gene333	2.015e-06	55.0	2EDT1@1|root,337NE@2|Bacteria,2GSX7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2171241_4	58123.JOFJ01000029_gene1111	2.217e-63	224.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EG0W@85012|Streptosporangiales	201174|Actinobacteria	T	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_2171241_1	1211815.CBYP010000062_gene3184	7.989e-120	407.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4EUN5@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158535_k127_2171241_2	58123.JOFJ01000029_gene1113	2.084e-108	373.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_2171241_8	749927.AMED_7933	3.981e-49	191.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4E7AU@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158535_k127_2171241_11	208439.AJAP_05390	5.089e-35	137.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_2171241_10	749927.AMED_7931	1.711e-35	139.0	COG0346@1|root,COG0346@2|Bacteria,2HMXH@201174|Actinobacteria,4E4WH@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_2171241_6	298654.FraEuI1c_0302	6.434e-58	214.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4ESRA@85013|Frankiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158535_k127_2171241_13	671143.DAMO_1273	1.659e-25	114.0	COG1276@1|root,COG1276@2|Bacteria	2|Bacteria	P	copper resistance	-	-	-	ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	AhpC-TSA,CopC,CopD,Cyt-b5,Cytochrome_CBB3
SRR25158535_k127_2171241_9	479435.Kfla_5813	2.777e-38	145.0	2DX9S@1|root,3441J@2|Bacteria,2IT0X@201174|Actinobacteria,4DS35@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
SRR25158535_k127_2171241_0	526225.Gobs_0795	9.619e-196	646.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4ESBD@85013|Frankiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
SRR25158535_k127_2171241_7	1123023.JIAI01000003_gene2671	4.481e-56	215.0	COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4E0TE@85010|Pseudonocardiales	201174|Actinobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
SRR25158535_k127_2171241_3	1304883.KI912532_gene1157	1.975e-85	290.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,2KUAD@206389|Rhodocyclales	206389|Rhodocyclales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SRR25158535_k127_2171241_5	1907.SGLAU_08480	5.478e-60	216.0	COG1234@1|root,COG1234@2|Bacteria,2GMEX@201174|Actinobacteria	201174|Actinobacteria	S	Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SRR25158535_k127_2171241_12	1380347.JNII01000006_gene1973	1.967e-30	123.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4ERE1@85013|Frankiales	201174|Actinobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
SRR25158535_k127_217637_1	1120950.KB892801_gene1744	9.565e-59	213.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4DPBH@85009|Propionibacteriales	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_217637_0	479434.Sthe_1990	3.85e-111	372.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158535_k127_2180551_0	1123024.AUII01000036_gene3135	1.81e-45	170.0	COG1597@1|root,COG1597@2|Bacteria,2GNNM@201174|Actinobacteria,4E66K@85010|Pseudonocardiales	201174|Actinobacteria	G	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158535_k127_2180551_2	1120949.KB903329_gene9217	4.371e-19	96.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
SRR25158535_k127_2180551_5	1120949.KB903329_gene9217	3.652e-08	55.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
SRR25158535_k127_2180551_4	1394178.AWOO02000018_gene6626	4.046e-09	67.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_2180551_1	1157708.KB907451_gene4671	6.243e-41	156.0	COG0454@1|root,COG0456@2|Bacteria,1RIS8@1224|Proteobacteria,2VX6G@28216|Betaproteobacteria	28216|Betaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158535_k127_2180551_3	1179773.BN6_06180	3.117e-11	66.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria,4E5HW@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158535_k127_2180577_9	42256.RradSPS_2329	1.565e-09	67.0	COG2244@1|root,COG2244@2|Bacteria,2I4II@201174|Actinobacteria,4CTZ7@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
SRR25158535_k127_2180577_5	313590.MED134_13686	6.29e-57	210.0	COG2148@1|root,COG2148@2|Bacteria,4NFIA@976|Bacteroidetes,1HXE1@117743|Flavobacteriia,37DUM@326319|Dokdonia	976|Bacteroidetes	M	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SRR25158535_k127_2180577_6	105422.BBPM01000082_gene165	3.739e-26	126.0	COG2244@1|root,COG2244@2|Bacteria,2HRUW@201174|Actinobacteria,2NKCF@228398|Streptacidiphilus	201174|Actinobacteria	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
SRR25158535_k127_2180577_3	67356.KL575644_gene1933	4.685e-64	247.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2180577_2	477641.MODMU_2687	2.514e-90	310.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158535_k127_2180577_1	247490.KSU1_D0235	2.619e-94	327.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158535_k127_2180577_0	66429.JOFL01000028_gene5044	6.171e-200	634.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SRR25158535_k127_2180577_4	797114.C475_07971	4.586e-60	232.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SRR25158535_k127_2180577_11	1232410.KI421424_gene1621	2.33e-05	56.0	COG1618@1|root,COG1618@2|Bacteria,1R0HW@1224|Proteobacteria	1224|Proteobacteria	F	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SRR25158535_k127_2180577_7	1229203.KI301992_gene2161	6.58e-25	121.0	COG0489@1|root,COG0489@2|Bacteria,2GJ1Y@201174|Actinobacteria,3UXNU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
SRR25158535_k127_2180577_8	35754.JNYJ01000001_gene7385	5.041e-24	111.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DCXI@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_2185511_2	383372.Rcas_0599	1.409e-50	182.0	COG1011@1|root,COG1011@2|Bacteria,2G7B3@200795|Chloroflexi,376JH@32061|Chloroflexia	32061|Chloroflexia	S	HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like)	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
SRR25158535_k127_2185511_1	1121019.AUMN01000008_gene3220	1.049e-92	326.0	COG1277@1|root,COG1277@2|Bacteria,2IG8D@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
SRR25158535_k127_2185511_0	1121019.AUMN01000008_gene3219	2.111e-121	396.0	COG1131@1|root,COG1131@2|Bacteria,2GN8P@201174|Actinobacteria,1WCH5@1268|Micrococcaceae	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2195717_3	106370.Francci3_2917	1.074e-24	113.0	2DJF9@1|root,32UCW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2195717_2	471852.Tcur_0830	2.606e-89	304.0	COG3386@1|root,COG3386@2|Bacteria,2GNAZ@201174|Actinobacteria,4EGF0@85012|Streptosporangiales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2195717_1	2074.JNYD01000003_gene3974	1.227e-119	393.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4DXN1@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_2195717_0	1348663.KCH_03090	2.395e-212	670.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,2M4TX@2063|Kitasatospora	201174|Actinobacteria	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SRR25158535_k127_2203479_0	345341.KUTG_09787	2.742e-135	441.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4DYWI@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
SRR25158535_k127_2203479_2	1078020.KEK_06780	6.601e-24	109.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SRR25158535_k127_2203479_1	1313172.YM304_39200	1.688e-80	271.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CMVI@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SRR25158535_k127_2203795_2	68570.DC74_7874	2.494e-56	216.0	COG2320@1|root,COG2320@2|Bacteria,2IFSJ@201174|Actinobacteria	201174|Actinobacteria	H	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
SRR25158535_k127_2203795_3	263358.VAB18032_16525	2.211e-47	181.0	COG3339@1|root,COG3339@2|Bacteria,2IMCR@201174|Actinobacteria,4DGJP@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SRR25158535_k127_2203795_0	405948.SACE_4737	1.648e-127	423.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2ICDR@201174|Actinobacteria,4E6UB@85010|Pseudonocardiales	201174|Actinobacteria	I	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR25158535_k127_2203795_1	1123024.AUII01000014_gene4295	2.467e-126	412.0	COG3386@1|root,COG3386@2|Bacteria,2HE8D@201174|Actinobacteria,4E2FP@85010|Pseudonocardiales	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
SRR25158535_k127_2207219_2	1303692.SFUL_4584	9.747e-49	188.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pkn20	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158535_k127_2207219_0	358823.DF19_22420	1.762e-234	738.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158535_k127_2207219_1	298654.FraEuI1c_6124	3.13e-140	460.0	COG1249@1|root,COG1249@2|Bacteria,2GMP7@201174|Actinobacteria,4ES8Q@85013|Frankiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_2210957_1	66429.JOFL01000001_gene4430	3.268e-10	66.0	COG0741@1|root,COG0741@2|Bacteria,2HKTH@201174|Actinobacteria	201174|Actinobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2210957_0	351607.Acel_0231	2.288e-155	501.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4ERKP@85013|Frankiales	201174|Actinobacteria	H	PFAM Aminotransferase class-III	hemL	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_2211689_4	471852.Tcur_4057	9.888e-21	96.0	COG0789@1|root,COG0789@2|Bacteria,2GS3D@201174|Actinobacteria,4EJX1@85012|Streptosporangiales	201174|Actinobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158535_k127_2211689_1	1122223.KB890688_gene1533	4.103e-135	443.0	COG0499@1|root,COG0499@2|Bacteria,1WKSY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158535_k127_2211689_2	312284.A20C1_07538	2.8e-64	229.0	COG1989@1|root,COG1989@2|Bacteria,2HH3X@201174|Actinobacteria,3UXHM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DiS_P_DiS,Peptidase_A24
SRR25158535_k127_2211689_0	471852.Tcur_2953	3.632e-155	499.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4EIB5@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
SRR25158535_k127_2211689_3	292459.STH1949	5.667e-24	119.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
SRR25158535_k127_2212503_0	369723.Strop_2091	1.985e-83	294.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4D8TS@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2212503_2	1463917.JODC01000010_gene4209	1.074e-41	169.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158535_k127_2212503_1	935839.JAGJ01000004_gene2050	1.886e-69	245.0	29QBK@1|root,30BAT@2|Bacteria,2IH7J@201174|Actinobacteria,4F432@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2218227_6	1500257.JQNM01000002_gene4441	1.867e-25	113.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,4B7JT@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	zinc protease	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
SRR25158535_k127_2218227_4	882086.SacxiDRAFT_1810	2.474e-62	221.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4E709@85010|Pseudonocardiales	201174|Actinobacteria	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_2218227_5	487521.OCU_25840	3.786e-26	115.0	COG3688@1|root,COG3688@2|Bacteria,2HS1T@201174|Actinobacteria,23A4M@1762|Mycobacteriaceae	201174|Actinobacteria	S	YacP-like NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
SRR25158535_k127_2218227_1	1996.JOFO01000059_gene713	4.906e-143	465.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4EHCR@85012|Streptosporangiales	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
SRR25158535_k127_2218227_3	1122247.C731_3548	6.681e-86	301.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,232QT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
SRR25158535_k127_2218227_2	710111.FraQA3DRAFT_0552	2.043e-120	413.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158535_k127_2218227_7	33876.JNXY01000001_gene5749	7.749e-22	97.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4DB89@85008|Micromonosporales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
SRR25158535_k127_2218227_0	414684.RC1_1479	1.213e-191	619.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2JQBQ@204441|Rhodospirillales	204441|Rhodospirillales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_2220764_4	211114.JOEF01000026_gene367	4.019e-26	119.0	COG3409@1|root,COG3409@2|Bacteria,2HUBB@201174|Actinobacteria,4E7IY@85010|Pseudonocardiales	201174|Actinobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2220764_2	298655.KI912266_gene4753	1.073e-53	194.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158535_k127_2220764_1	106370.Francci3_3446	4.916e-67	238.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4EXB4@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2220764_6	471852.Tcur_0030	8.966e-14	73.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4EFKY@85012|Streptosporangiales	201174|Actinobacteria	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2220764_0	263358.VAB18032_18675	6.012e-119	390.0	COG2890@1|root,COG2890@2|Bacteria,2I3YD@201174|Actinobacteria,4DMFE@85008|Micromonosporales	201174|Actinobacteria	J	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158535_k127_2220764_3	680198.SCAB_0161	3.493e-48	182.0	COG3293@1|root,COG3293@2|Bacteria,2IIAY@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
SRR25158535_k127_2220764_5	1121943.KB900017_gene314	1.161e-18	93.0	COG3293@1|root,COG3293@2|Bacteria,1RJJ6@1224|Proteobacteria,1S7K1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
SRR25158535_k127_2232222_8	1054213.HMPREF9946_01796	2.424e-07	55.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SRR25158535_k127_2232222_5	1283299.AUKG01000005_gene34	7.379e-99	333.0	COG1879@1|root,COG1879@2|Bacteria,2GNSX@201174|Actinobacteria,4CS59@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SRR25158535_k127_2232222_1	1123320.KB889686_gene782	3.11e-128	419.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SRR25158535_k127_2232222_3	1283299.AUKG01000005_gene36	3.131e-103	358.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CRFV@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158535_k127_2232222_2	1157943.KB892705_gene555	1.712e-103	370.0	COG1070@1|root,COG1070@2|Bacteria,2IE7F@201174|Actinobacteria,238BH@1762|Mycobacteriaceae	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158535_k127_2232222_4	211114.JOEF01000005_gene2259	3.235e-103	349.0	COG1482@1|root,COG1482@2|Bacteria,2I8X4@201174|Actinobacteria,4DZK8@85010|Pseudonocardiales	201174|Actinobacteria	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SRR25158535_k127_2232222_0	1120949.KB903294_gene4026	2.775e-200	637.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D8RP@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158535_k127_2232222_7	1223523.H340_07281	8.317e-14	76.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_2232222_6	469383.Cwoe_0968	8.417e-22	96.0	COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_2237018_3	1121272.KB903255_gene5693	1.565e-37	151.0	COG1073@1|root,COG1073@2|Bacteria,2IPZT@201174|Actinobacteria,4DFKK@85008|Micromonosporales	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DLH,Hydrolase_4
SRR25158535_k127_2237018_1	2074.JNYD01000029_gene7188	1.162e-109	384.0	COG1807@1|root,COG1807@2|Bacteria,2GK3Q@201174|Actinobacteria,4DZ07@85010|Pseudonocardiales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SRR25158535_k127_2237018_0	649831.L083_4723	5.943e-162	543.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_2237018_5	222534.KB893802_gene4002	8.543e-08	63.0	COG1193@1|root,COG1193@2|Bacteria	2|Bacteria	L	negative regulation of DNA recombination	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SRR25158535_k127_2237018_4	1122921.KB898211_gene2811	1.322e-25	117.0	COG2128@1|root,COG2128@2|Bacteria,1U08V@1239|Firmicutes,4I9JR@91061|Bacilli,271NZ@186822|Paenibacillaceae	91061|Bacilli	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2237018_2	861299.J421_0396	3.745e-98	330.0	COG1028@1|root,COG1028@2|Bacteria,1ZV1D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158535_k127_2241742_2	1229780.BN381_80399	1.627e-09	72.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,3UWIA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Displays ATPase and GTPase activities	yvcJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SRR25158535_k127_2241742_0	1896.JOAU01000001_gene4310	1.35e-225	715.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
SRR25158535_k127_2241742_1	1382306.JNIM01000001_gene2629	7.177e-112	381.0	2DB7W@1|root,2Z7P1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
SRR25158535_k127_2246589_3	469383.Cwoe_3536	2.039e-58	218.0	COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_2246589_1	1386089.N865_19145	2.048e-158	505.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4FH5U@85021|Intrasporangiaceae	201174|Actinobacteria	S	alcohol dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
SRR25158535_k127_2246589_0	882083.SacmaDRAFT_2591	1.608e-167	537.0	COG2159@1|root,COG2159@2|Bacteria,2I9CM@201174|Actinobacteria,4E0SZ@85010|Pseudonocardiales	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158535_k127_2246589_2	1123024.AUII01000002_gene1134	2.842e-69	241.0	COG2151@1|root,COG2151@2|Bacteria,2IAEQ@201174|Actinobacteria,4E453@85010|Pseudonocardiales	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158535_k127_2276133_2	1286171.EAL2_808p03430	7.536e-23	109.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25X8C@186806|Eubacteriaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158535_k127_2276133_0	471852.Tcur_2993	1.107e-108	367.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4EGFE@85012|Streptosporangiales	201174|Actinobacteria	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SRR25158535_k127_2276133_1	562970.Btus_1823	6.281e-51	184.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,279P7@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
SRR25158535_k127_2288650_5	243159.AFE_0478	2.453e-07	57.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,1SPNM@1236|Gammaproteobacteria,2ND7Z@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158535_k127_2288650_2	1123023.JIAI01000003_gene3073	2.248e-48	183.0	COG0451@1|root,COG0451@2|Bacteria,2HQWK@201174|Actinobacteria,4E9XH@85010|Pseudonocardiales	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2288650_4	211114.JOEF01000009_gene1697	5.103e-25	114.0	COG0451@1|root,COG0451@2|Bacteria,2HQWK@201174|Actinobacteria,4E9XH@85010|Pseudonocardiales	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2288650_1	102129.Lepto7375DRAFT_0184	1.479e-84	316.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,WD40
SRR25158535_k127_2288650_3	351607.Acel_0793	1.004e-30	122.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4ERS4@85013|Frankiales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158535_k127_2289867_5	570952.ATVH01000001_gene916	1.374e-11	76.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U0KM@28211|Alphaproteobacteria,2JT28@204441|Rhodospirillales	204441|Rhodospirillales	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158535_k127_2289867_6	4530.OS01T0122000-01	0.0009765	48.0	2CQD4@1|root,2R4G2@2759|Eukaryota,385CN@33090|Viridiplantae,3GTBY@35493|Streptophyta,3MA1C@4447|Liliopsida,3IRW6@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2289867_2	298653.Franean1_7244	6.055e-52	206.0	2DE9Z@1|root,32U2Z@2|Bacteria,2ID6V@201174|Actinobacteria,4EW0B@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2289867_1	1122138.AQUZ01000033_gene3623	1.607e-62	227.0	COG3336@1|root,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4DQ1Q@85009|Propionibacteriales	201174|Actinobacteria	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG
SRR25158535_k127_2289867_3	1122138.AQUZ01000097_gene6896	1.137e-17	96.0	COG3809@1|root,COG3809@2|Bacteria,2IKNG@201174|Actinobacteria,4DSHZ@85009|Propionibacteriales	201174|Actinobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
SRR25158535_k127_2289867_4	1394178.AWOO02000030_gene4733	1.481e-16	90.0	COG2755@1|root,COG2755@2|Bacteria,2IPPH@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SRR25158535_k127_2289867_0	56110.Oscil6304_2103	4.819e-66	246.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1H8MW@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158535_k127_2292057_8	1121019.AUMN01000038_gene23	1.643e-05	49.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SRR25158535_k127_2292057_3	665577.JH993790_gene5690	1.312e-37	144.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
SRR25158535_k127_2292057_2	68219.JNXI01000003_gene4744	4.017e-45	169.0	COG0346@1|root,COG0346@2|Bacteria,2IM7G@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_2292057_6	330084.JNYZ01000010_gene6890	1.73e-17	87.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria,4E70D@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SRR25158535_k127_2292057_0	208439.AJAP_32835	5.764e-189	604.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4DXSS@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase or acyltransferase of alpha beta superfamily	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN,MDMPI_N
SRR25158535_k127_2292057_1	882083.SacmaDRAFT_0793	4.069e-140	456.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4E1PX@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SRR25158535_k127_2292057_7	590998.Celf_0154	1.988e-09	69.0	2EI6P@1|root,33BY0@2|Bacteria,2H6KP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2292057_4	471853.Bcav_0109	2.2e-26	114.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
SRR25158535_k127_2293373_1	266117.Rxyl_2657	8.942e-35	132.0	COG2159@1|root,COG2159@2|Bacteria,2I9CM@201174|Actinobacteria,4CRK1@84995|Rubrobacteria	201174|Actinobacteria	S	amidohydrolase 2	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158535_k127_2293373_0	1193181.BN10_1060003	3.339e-233	735.0	COG2373@1|root,COG2373@2|Bacteria,2GTY9@201174|Actinobacteria	201174|Actinobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158535_k127_2304020_1	1246995.AFR_26500	8.821e-42	157.0	COG3832@1|root,COG3832@2|Bacteria,2IHQF@201174|Actinobacteria,4DFBR@85008|Micromonosporales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_2304020_0	1267535.KB906767_gene2627	1.873e-63	235.0	COG0025@1|root,COG0025@2|Bacteria,3Y96Q@57723|Acidobacteria,2JNWA@204432|Acidobacteriia	2|Bacteria	P	Sodium/hydrogen exchanger family	nhaP	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158535_k127_2304549_1	1380391.JIAS01000003_gene1909	4.015e-112	378.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2JV15@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158535_k127_2304549_4	246196.MSMEI_0647	6.77e-09	62.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,234PD@1762|Mycobacteriaceae	201174|Actinobacteria	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158535_k127_2304549_3	931627.MycrhDRAFT_3645	1.804e-15	85.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,234PD@1762|Mycobacteriaceae	201174|Actinobacteria	Q	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158535_k127_2304549_2	710687.KI912270_gene398	1.581e-41	162.0	COG1309@1|root,COG1309@2|Bacteria,2GNDM@201174|Actinobacteria,234I6@1762|Mycobacteriaceae	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158535_k127_2304549_0	318424.EU78_02895	3.006e-152	488.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,23EUD@1762|Mycobacteriaceae	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_2305147_0	106370.Francci3_3446	2.493e-75	259.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4EXB4@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2305147_1	390989.JOEG01000011_gene240	7.316e-51	198.0	COG4585@1|root,COG4585@2|Bacteria,2HQ5U@201174|Actinobacteria,4DFTZ@85008|Micromonosporales	201174|Actinobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
SRR25158535_k127_2305147_2	390989.JOEG01000011_gene219	8.476e-50	199.0	COG2197@1|root,COG2197@2|Bacteria,2IFSK@201174|Actinobacteria,4DJ92@85008|Micromonosporales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	uvrY	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_2305147_3	1123251.ATWM01000002_gene63	2.756e-46	177.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4FGAT@85021|Intrasporangiaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_2305147_4	1274.HX89_08050	1.866e-05	48.0	COG0438@1|root,COG0438@2|Bacteria,2I0UF@201174|Actinobacteria,1ZWIW@145357|Dermacoccaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SRR25158535_k127_2305154_0	391037.Sare_0439	1.686e-106	357.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4D8ES@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	ltrA	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158535_k127_2305154_1	211114.JOEF01000004_gene6607	1.172e-60	216.0	COG2353@1|root,COG2353@2|Bacteria,2GJFT@201174|Actinobacteria,4EENR@85010|Pseudonocardiales	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SRR25158535_k127_2305154_2	1283283.ATXA01000019_gene2958	6.962e-36	143.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4EUS9@85013|Frankiales	201174|Actinobacteria	S	low temperature requirement A	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158535_k127_2305777_4	1463861.JNXE01000001_gene4959	9.006e-19	88.0	COG0833@1|root,COG0833@2|Bacteria,2I418@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
SRR25158535_k127_2305777_1	1449976.KALB_1044	3.235e-148	474.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJX@85010|Pseudonocardiales	201174|Actinobacteria	V	Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_2305777_2	47763.JNZA01000009_gene5573	1.452e-101	338.0	COG0842@1|root,COG0842@2|Bacteria,2GIVW@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_2305777_0	749414.SBI_05548	0.0	1311.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158535_k127_2305777_3	471852.Tcur_4402	7.804e-73	251.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4EFI4@85012|Streptosporangiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
SRR25158535_k127_2307014_2	927704.SELR_03390	2.456e-78	273.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
SRR25158535_k127_2307014_0	469371.Tbis_0888	3.757e-115	384.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4DXDH@85010|Pseudonocardiales	201174|Actinobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	GO:0008150,GO:0040007	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158535_k127_2307014_3	1157637.KB892098_gene1982	3.219e-63	239.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
SRR25158535_k127_2307014_4	28042.GU90_18490	3.674e-56	208.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4DY0G@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the SUA5 family	ywlC	GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SRR25158535_k127_2307014_8	326424.FRAAL2037	1.759e-20	101.0	COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4ET83@85013|Frankiales	201174|Actinobacteria	T	low molecular weight	etp	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SRR25158535_k127_2307014_1	471852.Tcur_3925	4.764e-88	303.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4EH2S@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
SRR25158535_k127_2307014_11	749414.SBI_03784	1.946e-08	62.0	2BJAR@1|root,32DKN@2|Bacteria,2IFU9@201174|Actinobacteria	201174|Actinobacteria	-	-	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	-
SRR25158535_k127_2307014_5	1229780.BN381_10042	1.244e-54	201.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,3UWN7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SRR25158535_k127_2307014_9	1095772.CAHH01000073_gene610	1.556e-19	93.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SRR25158535_k127_2307014_7	926564.KI911710_gene2742	1.755e-23	107.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4F4GW@85017|Promicromonosporaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SRR25158535_k127_2307014_6	1352941.M877_11860	3.271e-33	138.0	COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria	201174|Actinobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,OSCP
SRR25158535_k127_2307571_5	1137268.AZXF01000010_gene2643	4.699e-06	58.0	COG2268@1|root,COG2268@2|Bacteria,2GKTJ@201174|Actinobacteria,4EHSF@85012|Streptosporangiales	201174|Actinobacteria	S	DivIVA protein	abpS	-	-	-	-	-	-	-	-	-	-	-	DivIVA
SRR25158535_k127_2307571_1	1111479.AXAR01000002_gene1899	3.592e-114	380.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2784A@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_2307571_3	1385518.N798_08140	4.425e-30	121.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4FHCX@85021|Intrasporangiaceae	201174|Actinobacteria	K	AsnC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158535_k127_2307571_2	351607.Acel_0966	3.18e-105	352.0	COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4ES7M@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SRR25158535_k127_2307571_0	710687.KI912270_gene2490	2.378e-149	486.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,2382Y@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_2307571_4	219305.MCAG_04602	8.32e-30	130.0	COG1396@1|root,COG1396@2|Bacteria,2GNZP@201174|Actinobacteria,4D8RX@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2308500_0	28042.GU90_12445	6.615e-134	446.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4E8S7@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
SRR25158535_k127_2308500_1	1123023.JIAI01000004_gene7826	4.241e-24	109.0	2B2YI@1|root,31VJH@2|Bacteria,2GVT3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2308500_2	1123023.JIAI01000004_gene7826	3.081e-12	69.0	2B2YI@1|root,31VJH@2|Bacteria,2GVT3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2308500_3	1123023.JIAI01000004_gene7831	3.347e-09	62.0	COG3301@1|root,COG3301@2|Bacteria	2|Bacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158535_k127_2315795_0	1210045.ALNP01000014_gene2751	1.889e-130	432.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria	201174|Actinobacteria	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
SRR25158535_k127_2315795_1	1089455.MOPEL_130_00840	1e-28	122.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4F6M6@85018|Dermatophilaceae	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_2320895_2	1449353.JQMQ01000005_gene2072	7.828e-05	46.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria,2NF68@228398|Streptacidiphilus	201174|Actinobacteria	K	Protein of unknown function (DUF742)	-	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR25158535_k127_2320895_1	479433.Caci_7863	1.521e-45	186.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria	201174|Actinobacteria	S	Roadblock lc7 family protein	cvnB6	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR25158535_k127_2320895_0	326424.FRAAL4397	1.056e-76	275.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158535_k127_2321486_4	710111.FraQA3DRAFT_4770	3.009e-23	99.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4ESB0@85013|Frankiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158535_k127_2321486_0	1155718.KB891892_gene6941	5.179e-152	495.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria	201174|Actinobacteria	M	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_2321486_3	2002.JOEQ01000022_gene6961	9.788e-47	182.0	COG0546@1|root,COG0546@2|Bacteria,2IKNN@201174|Actinobacteria,4EJVJ@85012|Streptosporangiales	201174|Actinobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158535_k127_2321486_2	1120950.KB892731_gene3814	4.062e-104	356.0	COG1070@1|root,COG1070@2|Bacteria,2IAKI@201174|Actinobacteria,4DTR5@85009|Propionibacteriales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158535_k127_2321486_1	644966.Tmar_0951	1.621e-139	454.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158535_k127_2323604_3	526227.Mesil_2353	2.363e-46	173.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_2323604_0	1380390.JIAT01000010_gene3934	1.149e-166	536.0	COG2373@1|root,COG2373@2|Bacteria,2GTY9@201174|Actinobacteria,4CRW7@84995|Rubrobacteria	84995|Rubrobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
SRR25158535_k127_2323604_10	446471.Xcel_0215	4.57e-06	57.0	28RSK@1|root,2ZE50@2|Bacteria,2GZBT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2323604_6	1229780.BN381_290078	7.924e-28	128.0	2C76P@1|root,32RIH@2|Bacteria,2IFWF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2323604_4	1248916.ANFY01000010_gene419	5.575e-37	143.0	COG1917@1|root,COG1917@2|Bacteria,1RHHY@1224|Proteobacteria,2UCCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
SRR25158535_k127_2323604_7	1335760.ASTG01000029_gene2354	1.652e-19	94.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U2WH@28211|Alphaproteobacteria,2KCB6@204457|Sphingomonadales	204457|Sphingomonadales	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SRR25158535_k127_2323604_1	326424.FRAAL5639	2.373e-70	256.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,4ERQA@85013|Frankiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2323604_11	479434.Sthe_2851	8.193e-05	51.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi	200795|Chloroflexi	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158535_k127_2323604_5	1408254.T458_19885	7.632e-28	116.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4HK2P@91061|Bacilli,276QJ@186822|Paenibacillaceae	91061|Bacilli	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SRR25158535_k127_2323604_8	1380394.JADL01000003_gene4815	9.258e-18	98.0	COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria,2U18B@28211|Alphaproteobacteria,2JUTA@204441|Rhodospirillales	204441|Rhodospirillales	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
SRR25158535_k127_2323604_9	1382304.JNIL01000001_gene3049	1.526e-15	83.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli	91061|Bacilli	E	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158535_k127_2323604_2	525904.Tter_1294	4.046e-59	214.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158535_k127_2328384_4	1394178.AWOO02000022_gene7207	6.473e-08	55.0	COG0745@1|root,COG0745@2|Bacteria,2I2Z1@201174|Actinobacteria,4EJHI@85012|Streptosporangiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_2328384_0	1121468.AUBR01000022_gene2786	1.967e-158	519.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,42ERB@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SRR25158535_k127_2328384_3	405948.SACE_1198	8.945e-52	196.0	COG3255@1|root,COG3255@2|Bacteria,2GJ5N@201174|Actinobacteria,4E360@85010|Pseudonocardiales	201174|Actinobacteria	I	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,SCP2
SRR25158535_k127_2328384_1	656024.FsymDg_3861	1.992e-144	473.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4ERJB@85013|Frankiales	201174|Actinobacteria	E	homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
SRR25158535_k127_2328384_2	469371.Tbis_0884	3.633e-138	469.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4DYEK@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_2340596_1	1380347.JNII01000006_gene1628	1.101e-110	374.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_2340596_3	345341.KUTG_05227	1.032e-70	258.0	2B0YS@1|root,31TBU@2|Bacteria,2GPJZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GT87
SRR25158535_k127_2340596_5	469383.Cwoe_2280	2.267e-18	91.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SRR25158535_k127_2340596_4	2074.JNYD01000006_gene1799	1.1e-25	113.0	2DPBC@1|root,331CT@2|Bacteria,2GS2F@201174|Actinobacteria,4E7UV@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2340596_0	390989.JOEG01000013_gene2562	8.374e-218	687.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4D8RM@85008|Micromonosporales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158535_k127_2340596_2	1120950.KB892769_gene5410	3.138e-104	344.0	COG0160@1|root,COG0160@2|Bacteria,2GKVH@201174|Actinobacteria,4DWMM@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-III	-	-	1.2.1.18,1.2.1.27,2.6.1.19	ko:K00140,ko:K00823	ko00250,ko00280,ko00410,ko00562,ko00640,ko00650,ko01100,ko01120,ko01200,map00250,map00280,map00410,map00562,map00640,map00650,map01100,map01120,map01200	M00013,M00027	R00705,R00706,R00908,R00922,R00935,R01648	RC00004,RC00006,RC00062,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_2341274_2	369723.Strop_2091	4.012e-23	100.0	COG1396@1|root,COG1396@2|Bacteria,2GIVR@201174|Actinobacteria,4D8TS@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2341274_3	58123.JOFJ01000005_gene1517	9.447e-20	96.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4EKKE@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158535_k127_2341274_4	452652.KSE_69200	1.112e-15	84.0	COG1917@1|root,COG1917@2|Bacteria,2IRV4@201174|Actinobacteria,2M409@2063|Kitasatospora	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2341274_0	68194.JNXR01000026_gene1566	2.61e-251	823.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12,Trans_reg_C
SRR25158535_k127_2341274_1	1120949.KB903296_gene9363	7.706e-42	157.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4D931@85008|Micromonosporales	201174|Actinobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_2347198_0	1343740.M271_29730	0.0	1150.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158535_k127_2347198_1	1304880.JAGB01000003_gene1070	1.298e-92	319.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158535_k127_2347198_2	1120949.KB903308_gene1193	3.492e-57	204.0	COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4D8GE@85008|Micromonosporales	201174|Actinobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16,5.3.1.24	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	M00023,M00026	R03509,R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SRR25158535_k127_2363301_7	1125971.ASJB01000064_gene6661	6.802e-38	147.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2363301_10	981369.JQMJ01000004_gene1572	9.286e-16	87.0	COG0346@1|root,COG0346@2|Bacteria,2GMSX@201174|Actinobacteria,2NI9D@228398|Streptacidiphilus	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_2363301_5	1172179.AUKV01000001_gene941	2.849e-67	233.0	COG3576@1|root,COG3576@2|Bacteria,2IG3P@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_2363301_8	1160718.SU9_33403	4.687e-25	121.0	2EFYZ@1|root,339R5@2|Bacteria,2GQSZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2363301_0	749414.SBI_02966	3.887e-116	400.0	COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158535_k127_2363301_9	591158.SSMG_04933	1.038e-16	92.0	COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158535_k127_2363301_2	211114.JOEF01000002_gene4649	3.226e-102	336.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4E0SE@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_2363301_6	1463825.JNXC01000003_gene3744	3.464e-41	170.0	COG0454@1|root,COG0456@2|Bacteria,2IAC7@201174|Actinobacteria,4E3WD@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	aac	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	2.3.1.59	ko:K17840	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_9
SRR25158535_k127_2363301_4	1120950.KB892823_gene451	1.663e-69	249.0	28NWW@1|root,2ZBUP@2|Bacteria,2IIH7@201174|Actinobacteria,4DUZI@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2363301_1	471852.Tcur_2468	5.179e-107	361.0	COG4585@1|root,COG4585@2|Bacteria,2GNBG@201174|Actinobacteria,4EGCT@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158535_k127_2363301_3	1394178.AWOO02000020_gene7471	3.395e-89	321.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4EH7N@85012|Streptosporangiales	201174|Actinobacteria	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_2363301_11	298655.KI912267_gene7290	6.66e-10	63.0	COG1309@1|root,COG1309@2|Bacteria,2IM5N@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158535_k127_2363301_12	258533.BN977_03809	9.315e-06	57.0	COG0654@1|root,COG0654@2|Bacteria,2GJ9V@201174|Actinobacteria,235AE@1762|Mycobacteriaceae	201174|Actinobacteria	CH	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158535_k127_2363338_0	1120948.KB903240_gene3935	0.0	1238.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4E0DG@85010|Pseudonocardiales	201174|Actinobacteria	EF	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SRR25158535_k127_2363338_2	351607.Acel_1297	2.082e-76	292.0	COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4ESI4@85013|Frankiales	201174|Actinobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SRR25158535_k127_2363338_1	1121430.JMLG01000006_gene1759	2.146e-88	319.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158535_k127_2363338_3	471852.Tcur_3009	1.446e-34	149.0	COG0284@1|root,COG0284@2|Bacteria,2HPEA@201174|Actinobacteria,4EHE6@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SRR25158535_k127_2369530_1	1220534.B655_0693	3.252e-66	241.0	arCOG03999@1|root,arCOG03999@2157|Archaea,2Y4KU@28890|Euryarchaeota	28890|Euryarchaeota	E	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
SRR25158535_k127_2369530_2	388399.SSE37_13131	1.533e-34	154.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria,1MUIQ@1224|Proteobacteria,2U1J0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT
SRR25158535_k127_2369530_0	1299327.I546_0741	1.214e-107	357.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
SRR25158535_k127_2369530_3	1429046.RR21198_2349	3.397e-15	75.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,4FYKI@85025|Nocardiaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
SRR25158535_k127_2373457_1	1123024.AUII01000010_gene790	2.256e-105	348.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria,4E0UA@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfurtransferase	sseA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158535_k127_2373457_0	370438.PTH_0664	1.577e-109	374.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,2603A@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158535_k127_2378641_2	1246995.AFR_35915	1.504e-35	136.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4DEJG@85008|Micromonosporales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SRR25158535_k127_2378641_0	298654.FraEuI1c_1109	3.79e-267	843.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4ERV5@85013|Frankiales	201174|Actinobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SRR25158535_k127_2378641_1	1210045.ALNP01000036_gene2348	7.496e-90	304.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
SRR25158535_k127_2392881_1	390989.JOEG01000004_gene3878	4.645e-11	68.0	COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4D9UB@85008|Micromonosporales	201174|Actinobacteria	S	Transmembrane domain of unknown function (DUF3566)	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
SRR25158535_k127_2392881_0	326424.FRAAL0009	1.571e-175	563.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4ERIW@85013|Frankiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV,Intein_splicing,LAGLIDADG_3
SRR25158535_k127_2414113_2	710696.Intca_0489	5.322e-148	480.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4FIKZ@85021|Intrasporangiaceae	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PKD,Peptidase_S8
SRR25158535_k127_2414113_14	1122138.AQUZ01000111_gene3275	1.07e-25	113.0	COG5649@1|root,COG5649@2|Bacteria,2GRMZ@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SRR25158535_k127_2414113_10	351607.Acel_2144	4.526e-32	142.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,2GIWB@201174|Actinobacteria,4ESXT@85013|Frankiales	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158535_k127_2414113_13	357808.RoseRS_2469	6.163e-28	124.0	COG1404@1|root,COG1404@2|Bacteria,2G7GP@200795|Chloroflexi,375SG@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM LPXTG-motif cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
SRR25158535_k127_2414113_6	1146883.BLASA_3902	2.651e-48	182.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4ET12@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158535_k127_2414113_0	1120948.KB903220_gene57	4.987e-226	723.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E1QR@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158535_k127_2414113_12	76114.ebA6278	1.274e-28	124.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,2KWA5@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_2414113_9	883103.HMPREF9703_00680	3.104e-32	137.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,27FNN@186828|Carnobacteriaceae	91061|Bacilli	T	helix_turn_helix, Lux Regulon	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
SRR25158535_k127_2414113_5	68170.KL590491_gene4793	3.261e-70	246.0	2E2ED@1|root,32XIY@2|Bacteria,2IKES@201174|Actinobacteria,4EBGF@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2414113_15	1463917.JODC01000006_gene7986	3.129e-10	65.0	2DRKZ@1|root,33C8D@2|Bacteria,2GWR3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2414113_11	469383.Cwoe_4202	9.31e-31	134.0	COG0526@1|root,COG0526@2|Bacteria,2HDQJ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2414113_3	469383.Cwoe_0139	1.877e-112	375.0	COG3214@1|root,COG3214@2|Bacteria,2HPYW@201174|Actinobacteria,4CRE6@84995|Rubrobacteria	84995|Rubrobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_2414113_1	196162.Noca_4918	1.01e-174	561.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4DT1D@85009|Propionibacteriales	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
SRR25158535_k127_2414113_4	1122138.AQUZ01000015_gene6845	1.808e-108	364.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4DVK7@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SRR25158535_k127_2414113_7	189753.AXAS01000002_gene5404	1.077e-45	180.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,3JRQB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158535_k127_2414113_8	1463854.JOHT01000015_gene5423	1.673e-34	138.0	COG1670@1|root,COG1670@2|Bacteria,2IIEK@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SRR25158535_k127_2414756_3	1214101.BN159_0146	1.723e-81	275.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria	201174|Actinobacteria	L	resolvase	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
SRR25158535_k127_2414756_0	525909.Afer_1427	3.157e-210	667.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2414756_4	262316.MAP_1093	1.261e-80	281.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,2347Q@1762|Mycobacteriaceae	201174|Actinobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
SRR25158535_k127_2414756_6	1232410.KI421416_gene2553	2.986e-32	143.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria,43SNK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
SRR25158535_k127_2414756_1	1179773.BN6_61420	6.762e-160	524.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DZQU@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158535_k127_2414756_5	1121877.JQKF01000024_gene2404	1.828e-66	253.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CMZZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SRR25158535_k127_2414756_7	68170.KL590492_gene6222	3.664e-28	128.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SRR25158535_k127_2414756_2	1370121.AUWS01000014_gene7180	3.945e-139	454.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,2387Z@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_2416221_4	1408445.JHXP01000047_gene1751	0.0006531	44.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1JECV@118969|Legionellales	118969|Legionellales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158535_k127_2416221_3	1380356.JNIK01000018_gene683	3.883e-10	64.0	COG0690@1|root,COG0690@2|Bacteria,2GQFP@201174|Actinobacteria,4ETD5@85013|Frankiales	201174|Actinobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SRR25158535_k127_2416221_1	1229780.BN381_350058	4.71e-67	234.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,3UWJ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
SRR25158535_k127_2416221_2	471852.Tcur_4355	7.547e-56	208.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4EJ4N@85012|Streptosporangiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SRR25158535_k127_2416221_0	1380356.JNIK01000018_gene680	4.457e-98	329.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4ERSC@85013|Frankiales	201174|Actinobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SRR25158535_k127_2418676_0	1125863.JAFN01000001_gene663	0.0	1013.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SRR25158535_k127_2418676_2	471852.Tcur_0705	1.348e-20	99.0	COG0517@1|root,COG0517@2|Bacteria,2I26I@201174|Actinobacteria,4EQHS@85012|Streptosporangiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158535_k127_2418676_1	455632.SGR_1231	1.227e-35	137.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,41804@629295|Streptomyces griseus group	201174|Actinobacteria	F	Amidohydrolase family	hyuA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
SRR25158535_k127_2422679_3	390989.JOEG01000001_gene5108	2.388e-27	112.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DDFZ@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_2422679_0	1120936.KB907212_gene5246	7.284e-88	300.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4EHZD@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2422679_1	1120936.KB907212_gene5247	2.435e-59	234.0	COG0577@1|root,COG0577@2|Bacteria,2I90E@201174|Actinobacteria,4EN3E@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158535_k127_2422679_2	926550.CLDAP_01460	9.226e-34	130.0	COG1028@1|root,COG1028@2|Bacteria,2G5Y7@200795|Chloroflexi	200795|Chloroflexi	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_2425007_3	469383.Cwoe_0785	6.874e-84	287.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SRR25158535_k127_2425007_5	470.IX87_20125	3.08e-32	135.0	COG1309@1|root,COG1309@2|Bacteria,1NE0F@1224|Proteobacteria,1S9XP@1236|Gammaproteobacteria,3NKUC@468|Moraxellaceae	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2425007_1	909613.UO65_1558	1.784e-169	539.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria,4EAZS@85010|Pseudonocardiales	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
SRR25158535_k127_2425007_4	1306174.JODP01000013_gene7828	2.376e-47	183.0	COG0258@1|root,COG0258@2|Bacteria,2I9H6@201174|Actinobacteria	201174|Actinobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158535_k127_2425007_0	656024.FsymDg_0772	2.898e-235	739.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4ES5K@85013|Frankiales	201174|Actinobacteria	H	Mg-chelatase subunit ChlI	chlI	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0958	Mg_chelatase,Sigma54_activat
SRR25158535_k127_2425007_2	1394178.AWOO02000047_gene6269	2.816e-158	535.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4EG1M@85012|Streptosporangiales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158535_k127_2429301_1	644283.Micau_2875	9.674e-61	214.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4DHQ1@85008|Micromonosporales	201174|Actinobacteria	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158535_k127_2429301_0	219305.MCAG_05434	3.196e-87	304.0	COG0673@1|root,COG0673@2|Bacteria,2IFZE@201174|Actinobacteria,4DHQ3@85008|Micromonosporales	201174|Actinobacteria	S	Putative oxidoreductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,ox_reductase_C
SRR25158535_k127_2429301_3	1394178.AWOO02000039_gene8616	0.0009153	44.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4EGDJ@85012|Streptosporangiales	201174|Actinobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_2429301_2	673860.AciM339_0784	8.951e-25	117.0	COG0730@1|root,arCOG02050@2157|Archaea,2Y68P@28890|Euryarchaeota,3F37D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SRR25158535_k127_2429368_0	477974.Daud_0304	7.291e-65	226.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158535_k127_2429368_2	1229203.KI301992_gene1276	3.211e-18	87.0	COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,3UWW8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Preprotein translocase SecG subunit	secG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SRR25158535_k127_2429368_1	1504822.CCNO01000015_gene570	1.001e-45	185.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5,TAT_signal
SRR25158535_k127_2430156_0	1123320.KB889580_gene1692	1.379e-96	327.0	COG0614@1|root,COG0614@2|Bacteria,2I2MI@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SRR25158535_k127_2430156_1	1386969.AWTB01000097_gene4430	4.971e-64	244.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4GCCV@85026|Gordoniaceae	201174|Actinobacteria	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158535_k127_2432811_2	309801.trd_1341	4.65e-31	128.0	COG2110@1|root,COG2110@2|Bacteria,2G7ID@200795|Chloroflexi,27YKP@189775|Thermomicrobia	189775|Thermomicrobia	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
SRR25158535_k127_2432811_0	338966.Ppro_3045	9.246e-57	223.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SRR25158535_k127_2432811_1	1313172.YM304_19370	8.942e-50	181.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CN5M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SRR25158535_k127_2434106_2	452652.KSE_52510	3.281e-20	92.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria,2M5NA@2063|Kitasatospora	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_2434106_1	1435356.Y013_12475	7.358e-83	280.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria,4G8SR@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2434106_0	471852.Tcur_2011	5.309e-120	389.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,4EGRA@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	rhlG	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SRR25158535_k127_243496_1	309801.trd_1336	2.212e-67	248.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
SRR25158535_k127_243496_0	926560.KE387023_gene2382	5.629e-117	396.0	COG0604@1|root,COG0604@2|Bacteria,1WM0U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SRR25158535_k127_243496_2	1077972.ARGLB_078_01110	3.172e-06	49.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,1WA2K@1268|Micrococcaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_2436483_2	1306406.ASHX01000001_gene1220	6.431e-34	139.0	COG3266@1|root,COG3266@2|Bacteria,2IB0P@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2436483_1	1122609.AUGT01000020_gene1045	1.385e-36	145.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2436483_3	1157632.AQWQ01000003_gene2091	7.09e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,2IT8W@201174|Actinobacteria	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2436483_0	234267.Acid_5058	4.296e-118	396.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	-	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_2437287_1	525903.Taci_1097	3.769e-76	264.0	COG1028@1|root,COG1028@2|Bacteria,3TAAZ@508458|Synergistetes	508458|Synergistetes	IQ	TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_2437287_2	937777.Deipe_1100	5.256e-17	84.0	COG0236@1|root,COG0236@2|Bacteria,1WKP9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SRR25158535_k127_2437287_0	1321781.HMPREF1985_01354	7.801e-89	302.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H2JV@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158535_k127_2437632_3	1463857.JOFZ01000002_gene5189	9.347e-05	49.0	COG0726@1|root,COG0726@2|Bacteria,2GMC2@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
SRR25158535_k127_2437632_2	460265.Mnod_0784	2.431e-06	57.0	COG3794@1|root,COG3794@2|Bacteria,1RI9G@1224|Proteobacteria,2U7KA@28211|Alphaproteobacteria,1JYY4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158535_k127_2437632_1	1122129.AUEF01000019_gene2260	9.628e-08	60.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_11,AAA_12,AAA_30,DUF559
SRR25158535_k127_2437632_0	1123023.JIAI01000001_gene6535	7.276e-11	64.0	COG1914@1|root,COG1914@2|Bacteria,2GMUT@201174|Actinobacteria,4E7I6@85010|Pseudonocardiales	201174|Actinobacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2439757_0	479432.Sros_4848	1.83e-93	320.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4EN7N@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_2439757_5	290399.Arth_0225	3.391e-06	56.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,1W7SI@1268|Micrococcaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_2439757_2	710111.FraQA3DRAFT_4078	1.017e-46	182.0	2CK3K@1|root,32SBH@2|Bacteria,2IQJH@201174|Actinobacteria,4EW1Y@85013|Frankiales	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
SRR25158535_k127_2439757_1	675635.Psed_4276	3.021e-58	208.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2439757_3	479431.Namu_1736	5.861e-45	168.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4ETBE@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2439757_4	457429.ABJI02000076_gene3030	4.117e-07	59.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SRR25158535_k127_2441026_0	357808.RoseRS_2905	1.223e-180	578.0	COG0236@1|root,COG0304@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG0304@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2G68I@200795|Chloroflexi,3765Y@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
SRR25158535_k127_2444487_3	644966.Tmar_0770	1.178e-09	65.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,24EBI@186801|Clostridia	186801|Clostridia	S	PFAM DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
SRR25158535_k127_2444487_0	1089544.KB912942_gene1881	6.179e-208	668.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4DXVG@85010|Pseudonocardiales	201174|Actinobacteria	G	hydrolase, family 65, central catalytic	kojP	-	2.4.1.230	ko:K10231	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SRR25158535_k127_2444487_2	710696.Intca_0094	1.471e-99	340.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4FFM8@85021|Intrasporangiaceae	201174|Actinobacteria	I	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158535_k127_2444487_1	1283300.ATXB01000001_gene1711	4.737e-183	580.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	hydrolase family 65, central catalytic	ycjT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64,3.2.1.28,5.4.2.6	ko:K01194,ko:K01838,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SRR25158535_k127_2445374_3	351607.Acel_0515	2.276e-08	66.0	2BM3X@1|root,33KY1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2445374_1	996637.SGM_2385	1.948e-26	121.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria	201174|Actinobacteria	K	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Pyridox_ox_2
SRR25158535_k127_2445374_0	1394178.AWOO02000021_gene7351	3.192e-76	275.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GPUP@201174|Actinobacteria,4EFHA@85012|Streptosporangiales	201174|Actinobacteria	PQ	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
SRR25158535_k127_2445374_2	436229.JOEH01000005_gene3118	3.256e-14	73.0	COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,2NHAT@228398|Streptacidiphilus	201174|Actinobacteria	P	Major Facilitator Superfamily	narK2	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1,Sugar_tr
SRR25158535_k127_2449172_3	471857.Svir_13720	2.818e-36	144.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4E2P9@85010|Pseudonocardiales	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SRR25158535_k127_2449172_0	661478.OP10G_4359	1.057e-59	214.0	COG0035@1|root,COG0035@2|Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
SRR25158535_k127_2449172_4	543632.JOJL01000011_gene6834	8.909e-32	137.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria,4DEJD@85008|Micromonosporales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	ko:K08365	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
SRR25158535_k127_2449172_6	1089544.KB912942_gene490	7.686e-19	97.0	COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4E63A@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158535_k127_2449172_7	1283299.AUKG01000001_gene3170	4.644e-18	95.0	COG3324@1|root,COG3324@2|Bacteria,2HRAM@201174|Actinobacteria,4CT7I@84995|Rubrobacteria	84995|Rubrobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2449172_1	926550.CLDAP_37690	6.801e-52	189.0	COG1898@1|root,COG1898@2|Bacteria,2G7AS@200795|Chloroflexi	200795|Chloroflexi	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158535_k127_2449172_2	298654.FraEuI1c_2442	4.474e-46	173.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria,4ERCD@85013|Frankiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SRR25158535_k127_2459648_2	1172188.KB911821_gene1636	1.247e-26	113.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4FFKI@85021|Intrasporangiaceae	201174|Actinobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158535_k127_2459648_1	1046724.KB889921_gene120	4.961e-33	144.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria,1S2SK@1236|Gammaproteobacteria,46DGG@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
SRR25158535_k127_2459648_0	1068978.AMETH_3059	1.866e-130	433.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4DZCT@85010|Pseudonocardiales	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR25158535_k127_2460241_2	37659.JNLN01000001_gene171	5.552e-21	94.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,36DUP@31979|Clostridiaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158535_k127_2460241_1	882083.SacmaDRAFT_1071	3.801e-64	232.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,4DYAZ@85010|Pseudonocardiales	201174|Actinobacteria	T	Belongs to the peptidase S16 family	lon	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
SRR25158535_k127_2460241_0	656024.FsymDg_0937	4.373e-212	694.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4ERVJ@85013|Frankiales	201174|Actinobacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
SRR25158535_k127_2460241_3	29306.JOBE01000008_gene4679	2.092e-06	49.0	COG0790@1|root,COG0790@2|Bacteria,2GKCE@201174|Actinobacteria	201174|Actinobacteria	KLT	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1,TPR_10,TPR_16,TPR_4
SRR25158535_k127_246118_2	1380394.JADL01000010_gene4393	1.139e-67	239.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2JV15@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158535_k127_246118_1	1463825.JNXC01000008_gene1390	2.443e-80	288.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4E037@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_246118_0	1463825.JNXC01000008_gene1391	9.009e-88	297.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2463670_10	1121013.P873_07215	4.518e-17	87.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,1RM7W@1236|Gammaproteobacteria,1X48Q@135614|Xanthomonadales	135614|Xanthomonadales	E	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_8
SRR25158535_k127_2463670_4	561175.KB894093_gene2818	9.37e-84	286.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4EH8M@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SRR25158535_k127_2463670_11	545696.HOLDEFILI_03773	1.117e-11	77.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,3VS8E@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Putative transposase DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_2463670_9	1120949.KB903307_gene1465	3.046e-45	181.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_2463670_1	479435.Kfla_5733	1.303e-185	594.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4DNQ0@85009|Propionibacteriales	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158535_k127_2463670_8	1382306.JNIM01000001_gene2904	2.023e-47	175.0	COG2320@1|root,COG2320@2|Bacteria,2G94B@200795|Chloroflexi	200795|Chloroflexi	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
SRR25158535_k127_2463670_0	1123024.AUII01000019_gene3993	1.772e-222	709.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DZ94@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SRR25158535_k127_2463670_5	351607.Acel_0176	4.357e-63	225.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4ES85@85013|Frankiales	201174|Actinobacteria	L	TIGRFAM hydrolase, TatD family	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SRR25158535_k127_2463670_6	1120941.AUBL01000015_gene2598	3.707e-59	216.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4D3QK@85005|Actinomycetales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SRR25158535_k127_2463670_7	1240349.ANGC01000001_gene2609	2.054e-51	204.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4FTYE@85025|Nocardiaceae	201174|Actinobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158535_k127_2463670_2	405948.SACE_0817	2.042e-130	432.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DZZ7@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SRR25158535_k127_2463670_3	935866.JAER01000005_gene98	2.023e-85	291.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4DP73@85009|Propionibacteriales	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SRR25158535_k127_2473133_0	909663.KI867149_gene3292	4.774e-158	513.0	COG1483@1|root,COG1483@2|Bacteria,1MX1G@1224|Proteobacteria,42VAG@68525|delta/epsilon subdivisions,2WREB@28221|Deltaproteobacteria,2MQVP@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF499)	-	-	-	ko:K06922	-	-	-	-	ko00000	-	-	-	DUF499
SRR25158535_k127_2473133_1	390989.JOEG01000005_gene2023	1.394e-42	163.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4D9XK@85008|Micromonosporales	201174|Actinobacteria	G	phosphomannomutase	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158535_k127_2477100_2	351607.Acel_0987	1.006e-10	62.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4ES56@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0008150,GO:0040007	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
SRR25158535_k127_2477100_1	1206731.BAGB01000070_gene6847	2.935e-67	239.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4FVAR@85025|Nocardiaceae	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
SRR25158535_k127_2477100_0	481448.Minf_0010	1.902e-89	319.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158535_k127_2477748_0	365528.KB891208_gene3043	3.144e-46	188.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4ES1J@85013|Frankiales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158535_k127_2477748_1	29306.JOBE01000008_gene4704	1.961e-39	169.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD2	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158535_k127_2491867_14	405948.SACE_2450	6.224e-11	63.0	COG2239@1|root,COG2239@2|Bacteria,2I9TV@201174|Actinobacteria,4EEP1@85010|Pseudonocardiales	201174|Actinobacteria	P	Divalent cation transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE
SRR25158535_k127_2491867_7	479431.Namu_2002	2.323e-57	210.0	COG1277@1|root,COG1277@2|Bacteria,2GSIR@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
SRR25158535_k127_2491867_4	479431.Namu_2001	7.18e-75	264.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4ESB1@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,PLDc_N
SRR25158535_k127_2491867_2	243090.RB12344	3.121e-107	366.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
SRR25158535_k127_2491867_11	1463825.JNXC01000031_gene1597	1.7e-24	113.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4E2AY@85010|Pseudonocardiales	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158535_k127_2491867_12	1157637.KB892091_gene5414	9.711e-22	100.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_2491867_13	298655.KI912267_gene6804	1.217e-11	76.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_2491867_5	1380390.JIAT01000014_gene6273	5.128e-65	238.0	COG2267@1|root,COG2267@2|Bacteria,2HFRI@201174|Actinobacteria,4CQZ8@84995|Rubrobacteria	84995|Rubrobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,SCP2
SRR25158535_k127_2491867_0	1380356.JNIK01000015_gene2521	1.689e-179	580.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4EUAJ@85013|Frankiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	tgs1	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
SRR25158535_k127_2491867_8	1123322.KB904654_gene876	1.345e-53	194.0	COG1028@1|root,COG1028@2|Bacteria,2I32I@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_2491867_15	1463885.KL578528_gene6934	8.142e-09	63.0	COG1028@1|root,COG1028@2|Bacteria,2I32I@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_2491867_6	234621.RER_34100	7.909e-61	220.0	COG0332@1|root,COG0332@2|Bacteria,2IK61@201174|Actinobacteria,4FXDQ@85025|Nocardiaceae	201174|Actinobacteria	I	synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158535_k127_2491867_1	525368.HMPREF0591_4204	2.944e-144	466.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria,23EW9@1762|Mycobacteriaceae	201174|Actinobacteria	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158535_k127_2491867_10	1114959.SZMC14600_01021	8.097e-39	153.0	COG2128@1|root,COG2128@2|Bacteria,2IB85@201174|Actinobacteria,4E7P7@85010|Pseudonocardiales	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158535_k127_2491867_3	390989.JOEG01000005_gene1814	6.006e-104	356.0	COG4221@1|root,COG4221@2|Bacteria,2GKJ8@201174|Actinobacteria,4DAZ6@85008|Micromonosporales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_2491867_9	208444.JNYY01000006_gene7264	3.288e-49	194.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4DYGY@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158535_k127_2495360_0	351607.Acel_0793	8.488e-89	312.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4ERS4@85013|Frankiales	201174|Actinobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SRR25158535_k127_2495360_2	1280954.HPO_04140	9.076e-31	134.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U9FW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
SRR25158535_k127_2495360_1	1254432.SCE1572_36775	2.49e-49	181.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
SRR25158535_k127_2513734_0	2045.KR76_23900	8.421e-244	763.0	COG3243@1|root,COG3243@2|Bacteria,2GNYP@201174|Actinobacteria,4DU4T@85009|Propionibacteriales	201174|Actinobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
SRR25158535_k127_2513734_1	1121385.AQXW01000004_gene1289	4.415e-204	640.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,1ZWPI@145357|Dermacoccaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_2513734_2	526225.Gobs_2383	4.579e-106	351.0	COG2267@1|root,COG2267@2|Bacteria,2I0NW@201174|Actinobacteria,4EVDX@85013|Frankiales	201174|Actinobacteria	I	TAP-like protein	-	-	3.1.1.76	ko:K22250	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158535_k127_2535568_6	55952.BU52_16990	1.518e-65	235.0	COG3483@1|root,COG3483@2|Bacteria,2GNB1@201174|Actinobacteria	201174|Actinobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
SRR25158535_k127_2535568_3	266117.Rxyl_3181	4.43e-134	434.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CU2F@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_2535568_5	146922.JOFU01000030_gene5213	2.641e-66	253.0	COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SRR25158535_k127_2535568_4	298654.FraEuI1c_6391	7.019e-102	340.0	COG1573@1|root,COG1573@2|Bacteria,2IE93@201174|Actinobacteria	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
SRR25158535_k127_2535568_1	1713.JOFV01000014_gene879	2.213e-201	644.0	COG0402@1|root,COG0402@2|Bacteria,2IB7M@201174|Actinobacteria,4F1V1@85016|Cellulomonadaceae	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_2535568_0	1288494.EBAPG3_30940	1.974e-219	698.0	COG0793@1|root,COG0793@2|Bacteria,1R88N@1224|Proteobacteria,2W1SE@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158535_k127_2535568_2	58123.JOFJ01000027_gene2789	5.354e-137	447.0	COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4EFPC@85012|Streptosporangiales	201174|Actinobacteria	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
SRR25158535_k127_2535568_7	262724.TT_C0031	1.421e-29	125.0	28TIQ@1|root,2ZFSJ@2|Bacteria,1WK1S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2542162_15	479434.Sthe_1242	6.021e-13	73.0	COG1595@1|root,COG1595@2|Bacteria,2G90X@200795|Chloroflexi,27Z65@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2542162_18	644966.Tmar_0449	3.588e-06	59.0	COG4454@1|root,COG4454@2|Bacteria,1U5BP@1239|Firmicutes,257DV@186801|Clostridia	186801|Clostridia	P	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158535_k127_2542162_0	909613.UO65_5367	1.434e-299	937.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DYVW@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SRR25158535_k127_2542162_12	103733.JNYO01000049_gene8373	3.552e-21	96.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria,4E6WI@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
SRR25158535_k127_2542162_6	471852.Tcur_0098	1.25e-71	263.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4EI03@85012|Streptosporangiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
SRR25158535_k127_2542162_13	1463900.JOIX01000005_gene1273	7.17e-21	108.0	COG5516@1|root,COG5516@2|Bacteria,2GKQZ@201174|Actinobacteria	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158535_k127_2542162_1	405948.SACE_4782	4.291e-175	568.0	COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4DYHV@85010|Pseudonocardiales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	yjcE	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
SRR25158535_k127_2542162_2	469371.Tbis_1673	3.474e-150	488.0	COG1940@1|root,COG1940@2|Bacteria,2IB2E@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	glcK	-	-	-	-	-	-	-	-	-	-	-	ROK
SRR25158535_k127_2542162_16	1283283.ATXA01000023_gene236	2.416e-11	67.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria	201174|Actinobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_2542162_17	1041522.MCOL_V201285	6.607e-08	65.0	COG0642@1|root,COG2199@1|root,COG2208@1|root,COG2205@2|Bacteria,COG2208@2|Bacteria,COG3706@2|Bacteria,2GK8P@201174|Actinobacteria,232KY@1762|Mycobacteriaceae	201174|Actinobacteria	T	Stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA,PAS_4,Response_reg,SpoIIE
SRR25158535_k127_2542162_10	561175.KB894103_gene1305	4.975e-31	132.0	COG2887@1|root,COG2887@2|Bacteria,2I94N@201174|Actinobacteria,4EIEW@85012|Streptosporangiales	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
SRR25158535_k127_2542162_8	561175.KB894103_gene1307	1.343e-69	247.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4EG9R@85012|Streptosporangiales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
SRR25158535_k127_2542162_3	1283299.AUKG01000002_gene4207	3.297e-140	460.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4CS03@84995|Rubrobacteria	84995|Rubrobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
SRR25158535_k127_2542162_5	1379698.RBG1_1C00001G1510	1.721e-72	264.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_2542162_4	1120950.KB892746_gene3516	1.057e-99	336.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
SRR25158535_k127_2542162_9	1150864.MILUP08_41735	9.649e-55	209.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158535_k127_2542162_11	1283300.ATXB01000001_gene716	2.043e-26	114.0	COG1051@1|root,COG1051@2|Bacteria,1QIBH@1224|Proteobacteria,1TG5S@1236|Gammaproteobacteria,1XFR5@135618|Methylococcales	135618|Methylococcales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_2542162_7	649638.Trad_0232	3.992e-70	249.0	COG0266@1|root,COG0266@2|Bacteria,1WJ25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158535_k127_2542162_14	160799.PBOR_12060	1.916e-15	87.0	COG2334@1|root,COG2334@2|Bacteria,1V8JD@1239|Firmicutes,4HT3U@91061|Bacilli,26UHW@186822|Paenibacillaceae	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SRR25158535_k127_254264_7	1150864.MILUP08_40370	5.683e-83	314.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4D9ZW@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SRR25158535_k127_254264_6	479433.Caci_7678	6.493e-104	357.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158535_k127_254264_4	671143.DAMO_2691	3.694e-146	478.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SRR25158535_k127_254264_2	1206730.BAGA01000079_gene1303	4.367e-174	569.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4FWHS@85025|Nocardiaceae	201174|Actinobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SRR25158535_k127_254264_12	1120948.KB903217_gene1465	1.911e-33	142.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4E4HB@85010|Pseudonocardiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158535_k127_254264_11	656024.FsymDg_3998	9.157e-42	169.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4ESIY@85013|Frankiales	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158535_k127_254264_9	351607.Acel_0275	2.851e-58	226.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4ESDX@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
SRR25158535_k127_254264_5	414996.IL38_04435	6.787e-117	393.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,408VE@622450|Actinopolysporales	201174|Actinobacteria	C	NADH dehydrogenase	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158535_k127_254264_0	477641.MODMU_4964	7.594e-209	678.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,4ES5W@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM NADH-quinone oxidoreductase, chain G	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SRR25158535_k127_254264_3	1385520.N802_08770	7.765e-165	540.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4FF36@85021|Intrasporangiaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SRR25158535_k127_254264_10	656024.FsymDg_4003	7.099e-42	170.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4ESCP@85013|Frankiales	201174|Actinobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SRR25158535_k127_254264_1	446470.Snas_1277	1.711e-181	593.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4EYAM@85014|Glycomycetales	201174|Actinobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	nuoD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158535_k127_254264_8	591157.SSLG_03965	1.461e-61	222.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158535_k127_2545473_3	1463820.JOGW01000010_gene1078	1.691e-52	193.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2545473_0	1380347.JNII01000006_gene1628	1.132e-141	478.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_2545473_1	266117.Rxyl_2662	1.625e-139	452.0	COG2421@1|root,COG2421@2|Bacteria,2HQSF@201174|Actinobacteria	201174|Actinobacteria	C	Acetamidase formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
SRR25158535_k127_2545473_4	1123023.JIAI01000001_gene6678	5.939e-11	74.0	COG3795@1|root,COG3795@2|Bacteria,2IKRD@201174|Actinobacteria,4E51J@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_2545473_2	234621.RER_37070	9.327e-77	266.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria,4G8T5@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_2546010_2	1206730.BAGA01000185_gene3653	2.154e-09	68.0	COG1051@1|root,COG1051@2|Bacteria,2IMF8@201174|Actinobacteria,4G138@85025|Nocardiaceae	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_2546010_1	446469.Sked_25850	5.321e-23	109.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria	201174|Actinobacteria	J	2'-5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
SRR25158535_k127_2546010_0	1122138.AQUZ01000084_gene8795	7.916e-109	360.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4DP5R@85009|Propionibacteriales	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
SRR25158535_k127_2547351_4	548477.HMPREF0294_2449	1.82e-74	256.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,22KVP@1653|Corynebacteriaceae	201174|Actinobacteria	H	Glutamate-1-semialdehyde aminotransferase	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_2547351_1	469383.Cwoe_3116	2.297e-148	479.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4CPP7@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2547351_0	1123024.AUII01000012_gene4253	4.039e-246	778.0	COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4DZ08@85010|Pseudonocardiales	201174|Actinobacteria	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	pepX	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
SRR25158535_k127_2547351_3	561175.KB894093_gene2671	2.121e-82	281.0	COG0020@1|root,COG0020@2|Bacteria,2GJCP@201174|Actinobacteria,4EHM4@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS2	GO:0003674,GO:0003824,GO:0016740,GO:0016765,GO:0033850	2.5.1.31,2.5.1.68	ko:K00806,ko:K12503	ko00900,ko01110,map00900,map01110	-	R06447,R08528	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158535_k127_2547351_7	28042.GU90_07205	8.641e-24	116.0	COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria,4E3NH@85010|Pseudonocardiales	201174|Actinobacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
SRR25158535_k127_2547351_6	479434.Sthe_0122	4.205e-49	185.0	COG2818@1|root,COG2818@2|Bacteria,2G78E@200795|Chloroflexi	200795|Chloroflexi	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SRR25158535_k127_2547351_2	1869.MB27_03825	2.025e-121	399.0	COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,4D9MN@85008|Micromonosporales	201174|Actinobacteria	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SRR25158535_k127_2547351_5	1120973.AQXL01000063_gene438	1.52e-49	183.0	COG0693@1|root,COG0693@2|Bacteria,1V1CG@1239|Firmicutes,4HFRX@91061|Bacilli,2796W@186823|Alicyclobacillaceae	91061|Bacilli	S	DJ-1/PfpI family	yraA	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SRR25158535_k127_2551462_4	196627.cg0391	3.926e-15	77.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria,22JS4@1653|Corynebacteriaceae	201174|Actinobacteria	M	4-epimerase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158535_k127_2551462_1	1120950.KB892796_gene2259	2.99e-66	233.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158535_k127_2551462_2	448385.sce4974	2.314e-51	192.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions,2WRC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_3,TetR_N
SRR25158535_k127_2551462_3	298655.KI912266_gene1012	1.824e-34	150.0	COG2208@1|root,COG2208@2|Bacteria,2GK3Y@201174|Actinobacteria,4EUZK@85013|Frankiales	201174|Actinobacteria	KT	PFAM Stage II sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SRR25158535_k127_2551462_0	644283.Micau_0078	5.523e-159	510.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4DAR6@85008|Micromonosporales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_2552060_0	351607.Acel_1394	2.823e-273	850.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales	201174|Actinobacteria	C	Aconitate hydratase 1	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158535_k127_255238_2	1048339.KB913029_gene468	3.178e-10	65.0	2E4ST@1|root,32ZM5@2|Bacteria,2GSCH@201174|Actinobacteria,4ETEF@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158535_k127_255238_0	471852.Tcur_4135	3.467e-74	280.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria,4EHDB@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158535_k127_255238_1	253839.SSNG_07226	9.168e-28	124.0	COG1652@1|root,COG3629@1|root,COG1652@2|Bacteria,COG3629@2|Bacteria,2I8YV@201174|Actinobacteria	201174|Actinobacteria	NU	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,LysM
SRR25158535_k127_2554925_2	1382356.JQMP01000003_gene2453	8.162e-65	235.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158535_k127_2554925_5	397278.JOJN01000004_gene1376	2.623e-25	121.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4DRMD@85009|Propionibacteriales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158535_k127_2554925_1	1122611.KB903971_gene2713	1.119e-104	353.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4EGEE@85012|Streptosporangiales	201174|Actinobacteria	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158535_k127_2554925_0	383372.Rcas_0306	1.947e-144	481.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,3766K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158535_k127_2554925_3	1120934.KB894438_gene4994	3.906e-45	176.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4E2WE@85010|Pseudonocardiales	201174|Actinobacteria	C	SUF system FeS assembly protein, NifU family	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SRR25158535_k127_2554925_4	931627.MycrhDRAFT_4987	3.397e-38	146.0	COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,2398P@1762|Mycobacteriaceae	201174|Actinobacteria	S	metal-sulfur cluster biosynthetic enzyme	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158535_k127_2554925_6	1123023.JIAI01000003_gene2919	3.17e-20	96.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4DXZR@85010|Pseudonocardiales	201174|Actinobacteria	HP	Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
SRR25158535_k127_2555556_1	930171.Asphe3_26370	4.556e-36	145.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,1W93Q@1268|Micrococcaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2555556_0	1380356.JNIK01000004_gene97	4.851e-85	287.0	COG1960@1|root,COG1960@2|Bacteria,2GNTA@201174|Actinobacteria,4EU1D@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE25_2	-	1.3.8.7	ko:K00249,ko:K00257	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04547,R04592,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC01942	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_2555825_4	1194165.CAJF01000017_gene3526	0.0003288	48.0	COG1653@1|root,COG1653@2|Bacteria,2H0FP@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158535_k127_2555825_3	351607.Acel_2110	1.664e-33	134.0	2CH5R@1|root,32S5B@2|Bacteria,2IQUR@201174|Actinobacteria,4ET3H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
SRR25158535_k127_2555825_2	2002.JOEQ01000014_gene5340	8.333e-38	144.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4EI8Q@85012|Streptosporangiales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158535_k127_2555825_1	292459.STH2125	7.129e-91	308.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158535_k127_2555825_0	1298880.AUEV01000005_gene900	1.337e-225	727.0	COG3408@1|root,COG3408@2|Bacteria,2ICEJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2556898_5	298654.FraEuI1c_5875	1.788e-147	475.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4ESZR@85013|Frankiales	201174|Actinobacteria	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SRR25158535_k127_2556898_0	266117.Rxyl_2839	0.0	1095.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CPP1@84995|Rubrobacteria	84995|Rubrobacteria	C	xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
SRR25158535_k127_2556898_1	266117.Rxyl_2838	1.314e-199	632.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4CPPR@84995|Rubrobacteria	84995|Rubrobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_2556898_8	1068978.AMETH_1596	1.191e-78	264.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E2JM@85010|Pseudonocardiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
SRR25158535_k127_2556898_6	1343740.M271_13710	3.947e-120	392.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_2556898_7	1306174.JODP01000001_gene5190	5.294e-93	334.0	COG3648@1|root,COG3648@2|Bacteria,2GK7W@201174|Actinobacteria	201174|Actinobacteria	Q	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin	uox	-	1.7.3.3	ko:K00365	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	M00546	R02106,R07981	RC02107,RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	Uricase
SRR25158535_k127_2556898_9	471852.Tcur_3128	4.093e-29	135.0	COG2351@1|root,COG2351@2|Bacteria,2IQUN@201174|Actinobacteria,4EKGA@85012|Streptosporangiales	201174|Actinobacteria	S	HIUase/Transthyretin family	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
SRR25158535_k127_2556898_4	448385.sce5877	5.359e-155	521.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
SRR25158535_k127_2556898_3	448385.sce5876	6.261e-161	518.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42RF2@68525|delta/epsilon subdivisions,2WP05@28221|Deltaproteobacteria,2YWCM@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158535_k127_2556898_2	1214242.B446_09760	5.524e-191	607.0	COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria	201174|Actinobacteria	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
SRR25158535_k127_2556916_5	1120948.KB903243_gene2353	2.114e-15	77.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4DZDM@85010|Pseudonocardiales	201174|Actinobacteria	GM	GDP-mannose 4,6 dehydratase	galE3	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
SRR25158535_k127_2556916_6	1394178.AWOO02000011_gene4018	4.529e-09	68.0	COG0642@1|root,COG2205@2|Bacteria,2I3JI@201174|Actinobacteria,4EHM8@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158535_k127_2556916_3	653045.Strvi_2324	2.908e-39	157.0	COG5002@1|root,COG5002@2|Bacteria,2GP6S@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158535_k127_2556916_4	1380390.JIAT01000009_gene2228	9.351e-29	130.0	COG2258@1|root,COG2258@2|Bacteria,2GRBQ@201174|Actinobacteria,4CQID@84995|Rubrobacteria	84995|Rubrobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
SRR25158535_k127_2556916_0	1449976.KALB_4824	1.162e-123	402.0	COG0491@1|root,COG0491@2|Bacteria,2HP5U@201174|Actinobacteria,4DYA9@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_2556916_1	208444.JNYY01000008_gene8638	1.233e-106	351.0	COG1028@1|root,COG1028@2|Bacteria,2I8MZ@201174|Actinobacteria,4E46F@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_2556916_2	67373.JOBF01000013_gene4373	2.434e-71	244.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2560802_7	1348663.KCH_12280	6.776e-40	158.0	COG0642@1|root,COG2205@2|Bacteria,2II4F@201174|Actinobacteria	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SRR25158535_k127_2560802_6	266117.Rxyl_0187	2.779e-51	208.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CQ94@84995|Rubrobacteria	84995|Rubrobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2560802_0	42256.RradSPS_2597	8.967e-294	915.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CPA7@84995|Rubrobacteria	84995|Rubrobacteria	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
SRR25158535_k127_2560802_5	1265310.CCBD010000007_gene2992	5.866e-54	204.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158535_k127_2560802_2	882082.SaccyDRAFT_3038	2.608e-171	567.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DZWM@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SRR25158535_k127_2560802_1	1218084.BBJK01000037_gene3486	8.527e-185	595.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1K18V@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
SRR25158535_k127_2560802_8	1394178.AWOO02000001_gene1228	2.976e-26	114.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4EQIN@85012|Streptosporangiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2560802_4	1246995.AFR_26875	2.04e-87	293.0	COG2197@1|root,COG2197@2|Bacteria,2IIDD@201174|Actinobacteria,4DJ23@85008|Micromonosporales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_2560802_3	1246995.AFR_26880	6.316e-112	390.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_2560802_9	1177594.MIC448_460020	4.135e-24	117.0	COG1942@1|root,COG1942@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
SRR25158535_k127_2561163_11	644283.Micau_2872	1.318e-39	151.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DHXP@85008|Micromonosporales	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2561163_3	1206729.BAFZ01000054_gene3058	1.093e-129	425.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4FYBJ@85025|Nocardiaceae	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
SRR25158535_k127_2561163_10	525909.Afer_1783	5.741e-59	220.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4CN01@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
SRR25158535_k127_2561163_2	909613.UO65_0744	6.948e-140	460.0	COG0530@1|root,COG0530@2|Bacteria,2GP6H@201174|Actinobacteria,4E18G@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
SRR25158535_k127_2561163_0	710686.Mycsm_03827	2.588e-175	556.0	COG0387@1|root,COG0387@2|Bacteria,2IA57@201174|Actinobacteria,234QT@1762|Mycobacteriaceae	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
SRR25158535_k127_2561163_8	314230.DSM3645_08962	1.247e-99	338.0	COG4398@1|root,COG4398@2|Bacteria,2IXYT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SRR25158535_k127_2561163_14	1313172.YM304_28820	2.1e-16	91.0	COG0741@1|root,COG0741@2|Bacteria,2IF18@201174|Actinobacteria	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158535_k127_2561163_6	1120917.AQXM01000063_gene2031	4.918e-116	387.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,1W7MS@1268|Micrococcaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SRR25158535_k127_2561163_12	1380346.JNIH01000031_gene1054	9.748e-35	134.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158535_k127_2561163_9	478801.Ksed_04530	7.537e-93	315.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,1ZWCD@145357|Dermacoccaceae	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
SRR25158535_k127_2561163_5	1236902.ANAS01000005_gene4770	4.168e-117	388.0	COG1071@1|root,COG1071@2|Bacteria,2GK3W@201174|Actinobacteria,4EG6N@85012|Streptosporangiales	201174|Actinobacteria	C	Dehydrogenase E1 component	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SRR25158535_k127_2561163_4	1283299.AUKG01000004_gene1220	1.452e-125	415.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria,4CPW0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158535_k127_2561163_7	469383.Cwoe_4156	4.491e-102	339.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4CP6Q@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_2561163_1	1463903.JOIZ01000011_gene3372	2.233e-153	507.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
SRR25158535_k127_2561163_13	887929.HMP0721_1762	2.672e-18	87.0	COG3695@1|root,COG3695@2|Bacteria,1UIU9@1239|Firmicutes,25ES2@186801|Clostridia,25ZUW@186806|Eubacteriaceae	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
SRR25158535_k127_2561163_15	58123.JOFJ01000001_gene3296	4.514e-06	51.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4EHK1@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158535_k127_2562808_1	1120950.KB892768_gene5344	1.909e-53	213.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DNEM@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_2562808_2	397278.JOJN01000006_gene1011	3.005e-07	64.0	COG1826@1|root,COG1826@2|Bacteria,2IR0U@201174|Actinobacteria,4DRKC@85009|Propionibacteriales	201174|Actinobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	GO:0008150,GO:0040007	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SRR25158535_k127_2562808_0	1150864.MILUP08_41735	1.391e-56	213.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4D8SX@85008|Micromonosporales	201174|Actinobacteria	V	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158535_k127_2564919_1	309801.trd_A0395	1.791e-134	449.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
SRR25158535_k127_2564919_2	1410634.JHVD01000001_gene1453	2.275e-43	183.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4DNSR@85009|Propionibacteriales	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158535_k127_2564919_0	1120950.KB892707_gene4795	4.295e-188	601.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4DPQI@85009|Propionibacteriales	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158535_k127_2566879_1	512565.AMIS_51130	1.019e-16	85.0	COG1175@1|root,COG1175@2|Bacteria,2GJ70@201174|Actinobacteria,4DHYB@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158535_k127_2566879_0	356851.JOAN01000016_gene6056	2.597e-155	501.0	COG1653@1|root,COG1653@2|Bacteria,2H0FP@201174|Actinobacteria,4DHSD@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158535_k127_2568188_3	1349820.M707_07545	5.49e-94	313.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria,1W7WU@1268|Micrococcaceae	201174|Actinobacteria	KT	Phage shock protein A, PspA	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SRR25158535_k127_2568188_1	526225.Gobs_0486	1.769e-167	549.0	COG1512@1|root,COG1512@2|Bacteria,2GMGW@201174|Actinobacteria,4EUHV@85013|Frankiales	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
SRR25158535_k127_2568188_0	266117.Rxyl_1765	9.521e-188	600.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CP8C@84995|Rubrobacteria	84995|Rubrobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_2568188_2	944435.AXAJ01000015_gene5406	4.031e-114	388.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
SRR25158535_k127_2568188_4	105425.BBPL01000053_gene5680	1.005e-25	113.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2I1PB@201174|Actinobacteria,2NMZI@228398|Streptacidiphilus	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2568188_5	1122611.KB903999_gene8178	1.145e-24	111.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4EI1A@85012|Streptosporangiales	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR25158535_k127_2574843_7	543632.JOJL01000203_gene5087	2.191e-07	57.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
SRR25158535_k127_2574843_1	298653.Franean1_3039	6.747e-57	204.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	2|Bacteria	L	Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve_3
SRR25158535_k127_2574843_3	557599.MKAN_04475	4.529e-39	159.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria,23ENN@1762|Mycobacteriaceae	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_2574843_0	557599.MKAN_04475	3.643e-280	876.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria,23ENN@1762|Mycobacteriaceae	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_2574843_2	557599.MKAN_04465	1.969e-54	195.0	COG3415@1|root,COG3415@2|Bacteria,2H6YF@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2574843_4	557599.MKAN_04460	2.627e-25	111.0	2EHAG@1|root,33B2C@2|Bacteria,2GY5W@201174|Actinobacteria	201174|Actinobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
SRR25158535_k127_2574843_5	298655.KI912266_gene4753	2.391e-23	106.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158535_k127_257519_1	251221.35210711	6.978e-37	151.0	COG3039@1|root,COG3039@2|Bacteria,1G52R@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158535_k127_257519_0	106370.Francci3_0101	1.121e-86	295.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
SRR25158535_k127_258348_0	1380393.JHVP01000005_gene3555	0.0	1152.0	COG1452@1|root,COG1452@2|Bacteria,2GNM6@201174|Actinobacteria,4ETSY@85013|Frankiales	201174|Actinobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
SRR25158535_k127_2586078_1	272568.GDI1566	1.181e-32	136.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,2JPB0@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SRR25158535_k127_2586078_0	656024.FsymDg_1590	6.104e-109	364.0	COG4221@1|root,COG4221@2|Bacteria,2IK15@201174|Actinobacteria	201174|Actinobacteria	S	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_2586078_2	2074.JNYD01000017_gene4311	1.093e-14	80.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DX6S@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
SRR25158535_k127_2586078_3	1509405.GV67_10485	0.0001777	46.0	COG0477@1|root,COG0477@2|Bacteria,1MWXZ@1224|Proteobacteria,2TT27@28211|Alphaproteobacteria,4BD2U@82115|Rhizobiaceae	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
SRR25158535_k127_2586650_4	1122609.AUGT01000012_gene4400	9.944e-06	49.0	COG2350@1|root,COG2350@2|Bacteria,2GV9T@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_2586650_2	1120950.KB892787_gene148	1.104e-18	93.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR25158535_k127_2586650_0	994479.GL877879_gene5608	3.241e-155	514.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E23Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
SRR25158535_k127_2586650_3	222534.KB893766_gene2942	1.048e-15	81.0	2FDBU@1|root,345DN@2|Bacteria	2|Bacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158535_k127_2586650_1	222534.KB893766_gene2941	4.377e-66	231.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_2587525_3	1236902.ANAS01000009_gene2405	4.822e-40	165.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4EG6R@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158535_k127_2587525_4	585531.HMPREF0063_12661	3.353e-20	95.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4DN7R@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2587525_1	298653.Franean1_1741	1.027e-122	402.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4ERRI@85013|Frankiales	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158535_k127_2587525_0	1907.SGLAU_02855	1.258e-179	579.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria	201174|Actinobacteria	E	PHP domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
SRR25158535_k127_2587525_2	1120936.KB907223_gene2519	3.926e-56	214.0	COG2094@1|root,COG2094@2|Bacteria,2GNW1@201174|Actinobacteria,4EG79@85012|Streptosporangiales	201174|Actinobacteria	L	Methylpurine-DNA glycosylase (MPG)	alkA	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SRR25158535_k127_2587525_5	1408427.JADB01000006_gene134	7.071e-09	57.0	2DTS4@1|root,33MFD@2|Bacteria,1PTGB@1224|Proteobacteria,2V5BU@28211|Alphaproteobacteria,48UEV@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2595257_1	1134445.AJJM01000101_gene4022	1.152e-151	498.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158535_k127_2595257_3	1150864.MILUP08_42606	7.541e-118	414.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,4D96S@85008|Micromonosporales	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
SRR25158535_k127_2595257_9	211114.JOEF01000008_gene1363	2.625e-20	103.0	2D1T0@1|root,32TBA@2|Bacteria,2I8E5@201174|Actinobacteria,4DZE1@85010|Pseudonocardiales	201174|Actinobacteria	S	Copper transport outer membrane protein, MctB	mctB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796	-	-	-	-	-	-	-	-	-	-	MctB
SRR25158535_k127_2595257_5	429009.Adeg_1389	4.599e-46	187.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,25E7R@186801|Clostridia,42FZK@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_2595257_6	1095767.CAHD01000216_gene2687	2.523e-34	143.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4F156@85016|Cellulomonadaceae	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2595257_0	1408254.T458_05535	2.593e-228	741.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
SRR25158535_k127_2595257_8	1463855.JOHV01000003_gene2132	2.131e-28	134.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria	201174|Actinobacteria	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158535_k127_2595257_2	219305.MCAG_04961	2.779e-147	481.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,4DA3S@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SRR25158535_k127_2595257_4	1120959.ATXF01000008_gene418	6.15e-85	307.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4FMIB@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158535_k127_2595257_10	552811.Dehly_0108	3.467e-15	85.0	COG1734@1|root,COG1734@2|Bacteria,2GAUG@200795|Chloroflexi,34DDM@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
SRR25158535_k127_2595257_7	1121422.AUMW01000001_gene2495	8.033e-33	132.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158535_k127_2599197_0	28444.JODQ01000004_gene6172	1.189e-120	404.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4EG0G@85012|Streptosporangiales	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
SRR25158535_k127_2599197_1	1380347.JNII01000005_gene3392	7.498e-61	213.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_260567_1	269800.Tfu_0655	4.902e-116	397.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4EFGD@85012|Streptosporangiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158535_k127_260567_10	1122221.JHVI01000005_gene585	8.251e-16	91.0	COG1254@1|root,COG1254@2|Bacteria,1WKQ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SRR25158535_k127_260567_6	1245475.ANAE01000161_gene850	3.294e-39	168.0	COG1376@1|root,COG1376@2|Bacteria,2INDP@201174|Actinobacteria,4EQW6@85012|Streptosporangiales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158535_k127_260567_5	1288079.AUKN01000001_gene4084	4.181e-43	169.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158535_k127_260567_3	931627.MycrhDRAFT_0610	8.661e-69	243.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria,233H2@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SRR25158535_k127_260567_2	269800.Tfu_0651	2.165e-80	287.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4EGGX@85012|Streptosporangiales	201174|Actinobacteria	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SRR25158535_k127_260567_12	561175.KB894094_gene1868	9.827e-14	78.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4EKKV@85012|Streptosporangiales	201174|Actinobacteria	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SRR25158535_k127_260567_8	1121933.AUHH01000012_gene3600	5.066e-35	142.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4DQUU@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SRR25158535_k127_260567_4	351607.Acel_1578	1.11e-57	211.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4ESMC@85013|Frankiales	201174|Actinobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SRR25158535_k127_260567_7	593907.Celgi_1161	1.28e-35	144.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4F1AX@85016|Cellulomonadaceae	201174|Actinobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SRR25158535_k127_260567_11	67275.JOAP01000062_gene6065	4.571e-15	86.0	COG2197@1|root,COG2197@2|Bacteria,2I9VX@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TrmB
SRR25158535_k127_260567_9	1003195.SCAT_4466	4.986e-32	137.0	COG1378@1|root,COG1378@2|Bacteria,2IB4E@201174|Actinobacteria	201174|Actinobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
SRR25158535_k127_260567_0	292459.STH1384	6.932e-160	522.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
SRR25158535_k127_2606946_0	292459.STH1143	5.539e-123	414.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,249ZJ@186801|Clostridia	186801|Clostridia	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
SRR25158535_k127_2606946_2	1229172.JQFA01000002_gene2612	7.81e-59	225.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1H93G@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
SRR25158535_k127_2606946_1	509190.Cseg_2337	1.385e-91	315.0	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,2TUDJ@28211|Alphaproteobacteria,2KGRX@204458|Caulobacterales	204458|Caulobacterales	I	3-phytase	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
SRR25158535_k127_2606946_3	1380390.JIAT01000010_gene4354	1.923e-39	157.0	COG1409@1|root,COG1409@2|Bacteria,2GVVJ@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
SRR25158535_k127_2607991_1	1283283.ATXA01000023_gene251	1.708e-38	149.0	COG3576@1|root,COG3576@2|Bacteria,2I2W4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158535_k127_2607991_4	1162668.LFE_2470	3.916e-09	66.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K11210	-	-	-	-	ko00000,ko01000	-	-	-	Glyoxalase
SRR25158535_k127_2607991_2	28444.JODQ01000002_gene4057	8.731e-29	129.0	COG0174@1|root,COG0174@2|Bacteria,2IFHQ@201174|Actinobacteria,4EIZ4@85012|Streptosporangiales	201174|Actinobacteria	E	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
SRR25158535_k127_2607991_0	1122138.AQUZ01000001_gene1469	2.587e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_2607991_3	469383.Cwoe_2222	9.705e-28	127.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4CPXP@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2613476_3	313589.JNB_10854	8.493e-29	125.0	COG2120@1|root,COG2120@2|Bacteria,2IBQH@201174|Actinobacteria,4FI8N@85021|Intrasporangiaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SRR25158535_k127_2613476_1	1121468.AUBR01000018_gene2687	2.841e-105	362.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,42F4H@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART Elongator protein 3 MiaB NifB	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158535_k127_2613476_2	570268.ANBB01000046_gene1390	1.161e-30	138.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4EJSG@85012|Streptosporangiales	201174|Actinobacteria	FG	HIT domain	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
SRR25158535_k127_2613476_0	357808.RoseRS_2053	1.642e-221	711.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,3765E@32061|Chloroflexia	32061|Chloroflexia	E	peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
SRR25158535_k127_2613476_4	1120936.KB907220_gene1930	4.231e-19	103.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4EFKP@85012|Streptosporangiales	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SRR25158535_k127_2617122_1	1121472.AQWN01000003_gene1420	3.103e-68	243.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SRR25158535_k127_2617122_0	246194.CHY_1492	4.554e-129	423.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,42ERE@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SRR25158535_k127_2623424_2	58344.JOEL01000008_gene1607	8.107e-92	307.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675,ko:K15466	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001,ko01000,ko01008	-	-	-	Acetyltransf_2
SRR25158535_k127_2623424_5	479432.Sros_1741	1.098e-55	199.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,4EJ5Y@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158535_k127_2623424_6	485913.Krac_10135	8.317e-43	171.0	COG2364@1|root,COG2364@2|Bacteria,2G742@200795|Chloroflexi	200795|Chloroflexi	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2623424_1	35754.JNYJ01000016_gene9287	1.978e-93	323.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DF11@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2623424_10	1245475.ANAE01000103_gene1627	1.07e-05	55.0	2DR18@1|root,339RQ@2|Bacteria,2I6ZB@201174|Actinobacteria,4EKVG@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2623424_9	290397.Adeh_3482	5.533e-21	101.0	COG0746@1|root,COG0746@2|Bacteria,1QXVT@1224|Proteobacteria,42U4M@68525|delta/epsilon subdivisions,2WQUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158535_k127_2623424_4	765420.OSCT_0512	8.232e-65	228.0	COG0406@1|root,COG0406@2|Bacteria,2G73Q@200795|Chloroflexi,37737@32061|Chloroflexia	32061|Chloroflexia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158535_k127_2623424_7	1128421.JAGA01000003_gene3533	3.29e-39	153.0	298YA@1|root,32VWC@2|Bacteria,2NRHS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
SRR25158535_k127_2623424_3	357808.RoseRS_0006	4.874e-71	256.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
SRR25158535_k127_2623424_0	330084.JNYZ01000027_gene8239	4.106e-134	447.0	COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_2623424_8	351607.Acel_1117	1.447e-22	99.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4ESWY@85013|Frankiales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_2633506_1	1150864.MILUP08_43438	6.943e-25	104.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4D9DX@85008|Micromonosporales	201174|Actinobacteria	C	Cysteine-rich domain	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
SRR25158535_k127_2633506_0	298655.KI912266_gene2345	2.433e-244	766.0	COG1139@1|root,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4ERCA@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM iron-sulfur cluster binding protein	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
SRR25158535_k127_2641128_1	469371.Tbis_2148	8.11e-06	58.0	COG0524@1|root,COG0524@2|Bacteria,2GP1C@201174|Actinobacteria,4DXYX@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SRR25158535_k127_2641128_0	566461.SSFG_05391	1.547e-52	201.0	COG2313@1|root,COG2313@2|Bacteria,2GK19@201174|Actinobacteria	201174|Actinobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
SRR25158535_k127_2642745_1	1385519.N801_01950	2.994e-15	78.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4FJIZ@85021|Intrasporangiaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
SRR25158535_k127_2642745_0	479431.Namu_2060	6.394e-90	309.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4ERY8@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_2642745_2	1410634.JHVD01000009_gene1729	6.096e-15	74.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2,rve_3
SRR25158535_k127_265472_1	1123024.AUII01000001_gene2785	1.347e-62	218.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria	2|Bacteria	I	Glycosyl Transferase	yvaM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C,Hydrolase_4
SRR25158535_k127_265472_0	404589.Anae109_3002	6.992e-152	497.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria,2YTTX@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
SRR25158535_k127_2656170_2	67315.JOBD01000013_gene6986	6.297e-70	244.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_2656170_1	1463920.JOGB01000016_gene5465	8.63e-92	318.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_2656170_0	1380393.JHVP01000001_gene2469	1.129e-103	353.0	COG1033@1|root,COG2409@1|root,COG1033@2|Bacteria,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria,4EURS@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_265684_2	1380390.JIAT01000010_gene3975	2.959e-38	153.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
SRR25158535_k127_265684_1	525909.Afer_1826	2.033e-69	246.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4CNF9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158535_k127_265684_0	526225.Gobs_3343	4.439e-152	503.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4ERM6@85013|Frankiales	201174|Actinobacteria	C	Cytochrome b	qcrB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158535_k127_265684_4	1120950.KB892707_gene4796	2.547e-05	53.0	2D9MJ@1|root,32TTI@2|Bacteria,2IFFM@201174|Actinobacteria,4DQZG@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the cytochrome c oxidase bacterial subunit CtaF family	ctaF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
SRR25158535_k127_265684_3	1206732.BAGD01000031_gene921	3.415e-23	101.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4FV1E@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158535_k127_2658011_0	1382306.JNIM01000001_gene4028	5.019e-87	299.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
SRR25158535_k127_2658011_1	58123.JOFJ01000002_gene2590	1.009e-07	62.0	COG0845@1|root,COG0845@2|Bacteria,2I8EY@201174|Actinobacteria,4ENCV@85012|Streptosporangiales	201174|Actinobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158535_k127_2660137_5	266117.Rxyl_1676	2.749e-13	73.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158535_k127_2660137_0	867903.ThesuDRAFT_01006	4.308e-161	526.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_2660137_2	562970.Btus_2110	6.387e-82	276.0	COG2452@1|root,COG2452@2|Bacteria,1V387@1239|Firmicutes,4IRW1@91061|Bacilli,279R1@186823|Alicyclobacillaceae	91061|Bacilli	L	Resolvase, N terminal domain	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	MerR,Resolvase
SRR25158535_k127_2660137_3	525904.Tter_0412	1.281e-36	153.0	COG0363@1|root,COG0363@2|Bacteria,2NPBM@2323|unclassified Bacteria	2|Bacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158535_k127_2660137_4	324602.Caur_0502	3.396e-26	125.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia	32061|Chloroflexia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158535_k127_2660137_1	479434.Sthe_2436	2.375e-97	323.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158535_k127_2661072_1	1449346.JQMO01000003_gene6646	1.504e-28	117.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,2M0H1@2063|Kitasatospora	201174|Actinobacteria	LV	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
SRR25158535_k127_2661072_3	222534.KB893766_gene2942	6.882e-14	76.0	2FDBU@1|root,345DN@2|Bacteria	2|Bacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158535_k127_2661072_0	222534.KB893766_gene2941	1.065e-198	635.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_2661072_2	311424.DhcVS_260	2.406e-14	76.0	COG1002@1|root,COG3757@1|root,COG1002@2|Bacteria,COG3757@2|Bacteria,2GAYR@200795|Chloroflexi,34DKN@301297|Dehalococcoidia	301297|Dehalococcoidia	V	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_266721_3	1089545.KB913037_gene7731	9.349e-34	136.0	COG1714@1|root,COG1714@2|Bacteria,2HGSH@201174|Actinobacteria,4E35T@85010|Pseudonocardiales	201174|Actinobacteria	S	RDD family	pra	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158535_k127_266721_1	1283299.AUKG01000001_gene2191	7.813e-112	371.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CP6J@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SRR25158535_k127_266721_2	43354.JOIJ01000025_gene3237	7.649e-96	329.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4E9JX@85010|Pseudonocardiales	201174|Actinobacteria	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_266721_0	106370.Francci3_0651	8.226e-135	441.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4ES6Z@85013|Frankiales	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SRR25158535_k127_266721_4	1298880.AUEV01000001_gene5432	2.129e-13	70.0	COG2185@1|root,COG2185@2|Bacteria,2IFJD@201174|Actinobacteria	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	icmB	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
SRR25158535_k127_266893_6	1045009.AFXQ01000030_gene695	3.311e-21	95.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,1W7PG@1268|Micrococcaceae	201174|Actinobacteria	E	acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_266893_5	675635.Psed_1821	1.092e-64	230.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4DYN5@85010|Pseudonocardiales	201174|Actinobacteria	E	TIGRFAM Acetolactate synthase, small subunit	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
SRR25158535_k127_266893_2	35754.JNYJ01000049_gene7875	1.567e-152	495.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4DASF@85008|Micromonosporales	201174|Actinobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SRR25158535_k127_266893_0	471852.Tcur_3546	1.265e-179	577.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4ER2C@85012|Streptosporangiales	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SRR25158535_k127_266893_1	1121422.AUMW01000006_gene800	7.085e-170	549.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,260GB@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SRR25158535_k127_266893_4	644283.Micau_5090	5.864e-122	400.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4DBEM@85008|Micromonosporales	201174|Actinobacteria	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158535_k127_266893_3	298655.KI912267_gene6751	2.317e-129	418.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4EX6N@85013|Frankiales	201174|Actinobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SRR25158535_k127_2671282_8	543632.JOJL01000004_gene4209	1.093e-53	192.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DBFV@85008|Micromonosporales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_2671282_1	1048339.KB913029_gene4723	1.234e-113	377.0	COG0388@1|root,COG0388@2|Bacteria,2H03Y@201174|Actinobacteria,4EVT7@85013|Frankiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158535_k127_2671282_6	28444.JODQ01000016_gene7163	3.694e-64	229.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4EJZ6@85012|Streptosporangiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
SRR25158535_k127_2671282_14	196162.Noca_0128	1.012e-25	125.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2IF18@201174|Actinobacteria,4DN6C@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158535_k127_2671282_18	526225.Gobs_1274	0.0001144	55.0	COG5660@1|root,COG5660@2|Bacteria,2IHDZ@201174|Actinobacteria,4ET94@85013|Frankiales	201174|Actinobacteria	S	Putative zinc-finger	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158535_k127_2671282_15	596153.Alide_2865	7.748e-21	106.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2VQPE@28216|Betaproteobacteria,4ADGF@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2671282_11	1122182.KB903814_gene3525	4.617e-42	160.0	COG0542@1|root,COG0542@2|Bacteria,2IRV0@201174|Actinobacteria,4DEHG@85008|Micromonosporales	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR25158535_k127_2671282_13	653045.Strvi_7821	9.142e-27	110.0	2E3V5@1|root,32YSE@2|Bacteria,2GQM1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23,Sigma70_r4_2
SRR25158535_k127_2671282_10	1380390.JIAT01000009_gene2005	1.403e-42	179.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158535_k127_2671282_3	378806.STAUR_0036	1.922e-101	350.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Major facilitator superfamily	MA20_25180	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SRR25158535_k127_2671282_17	390989.JOEG01000003_gene4458	8.628e-19	100.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria,4D9FS@85008|Micromonosporales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
SRR25158535_k127_2671282_4	479434.Sthe_1081	2.766e-90	321.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2671282_7	479434.Sthe_1082	5.59e-60	221.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158535_k127_2671282_5	479434.Sthe_1083	5.461e-86	295.0	COG1131@1|root,COG1131@2|Bacteria,2G69S@200795|Chloroflexi,27XTG@189775|Thermomicrobia	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2671282_12	1380393.JHVP01000006_gene4062	1.477e-33	150.0	2EUDF@1|root,33MVU@2|Bacteria,2H0P4@201174|Actinobacteria,4ETG3@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2671282_0	1267533.KB906739_gene2749	6.769e-121	428.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria,2JMPX@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2671282_2	471852.Tcur_4452	1.413e-113	391.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4EGFY@85012|Streptosporangiales	201174|Actinobacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
SRR25158535_k127_2671282_9	1160718.SU9_19710	4.759e-48	182.0	2EBHZ@1|root,335IE@2|Bacteria,2GNMR@201174|Actinobacteria	201174|Actinobacteria	S	Phosphatase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237	-	-	-	-	-	-	-	-	-	-	Phosphatase
SRR25158535_k127_2671282_16	1303518.CCALI_01870	1.255e-20	106.0	COG1341@1|root,COG1341@2|Bacteria	2|Bacteria	S	polynucleotide 5'-hydroxyl-kinase activity	-	-	-	ko:K06947	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CLP1_P
SRR25158535_k127_2671866_2	1123023.JIAI01000017_gene3546	2.16e-41	169.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4E8XM@85010|Pseudonocardiales	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_2671866_0	446468.Ndas_3523	4.659e-115	383.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4EM72@85012|Streptosporangiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_2671866_1	1370121.AUWS01000068_gene11	6.025e-64	225.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,23C7E@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_2671866_3	479432.Sros_6790	2.898e-39	152.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EGKM@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158535_k127_267675_2	525909.Afer_1355	6.671e-37	142.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,4CNUX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
SRR25158535_k127_267675_0	1121423.JONT01000014_gene1231	9.704e-49	189.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,260K3@186807|Peptococcaceae	186801|Clostridia	E	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SRR25158535_k127_267675_1	2045.KR76_12655	1.038e-47	187.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4DQED@85009|Propionibacteriales	201174|Actinobacteria	F	Cytidylate kinase	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SRR25158535_k127_267675_3	1463864.JOGO01000054_gene3168	1.343e-36	158.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158535_k127_2682256_0	222534.KB893696_gene178	1.066e-163	524.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4ERQ9@85013|Frankiales	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_2684815_6	1033730.CAHG01000015_gene643	6.117e-07	58.0	2CXFQ@1|root,32T1V@2|Bacteria,2GQYH@201174|Actinobacteria,4DRHS@85009|Propionibacteriales	201174|Actinobacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_2684815_7	313589.JNB_06629	2.317e-06	58.0	2E9Y4@1|root,3343S@2|Bacteria,2GR3H@201174|Actinobacteria,4FHBJ@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2684815_8	1304876.AZVC01000001_gene1613	9.18e-06	54.0	2EBSZ@1|root,335SP@2|Bacteria,2GUT0@201174|Actinobacteria,1WA5M@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158535_k127_2684815_0	1120950.KB892731_gene3758	2.149e-93	317.0	COG3832@1|root,COG3832@2|Bacteria,2IE7C@201174|Actinobacteria,4DRPP@85009|Propionibacteriales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_2684815_1	1120950.KB892731_gene3757	7.958e-56	198.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria,4DRX0@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158535_k127_2684815_5	1206737.BAGF01000016_gene718	1.085e-08	64.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2684815_2	1123023.JIAI01000010_gene8649	6.244e-32	141.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DXKC@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2688679_0	929712.KI912613_gene1359	1.483e-100	331.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4CPYK@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_2688679_1	469383.Cwoe_0292	7.077e-97	342.0	COG0642@1|root,COG2205@2|Bacteria,2GNUQ@201174|Actinobacteria,4CRHZ@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_2689120_2	42256.RradSPS_0628	1.502e-162	527.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4CPSG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
SRR25158535_k127_2689120_0	266117.Rxyl_0759	1.82e-200	637.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CQYS@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_2689120_1	266117.Rxyl_0773	2.057e-170	550.0	COG0531@1|root,COG0531@2|Bacteria,2IPSH@201174|Actinobacteria,4CQHF@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158535_k127_2694210_0	1116232.AHBF01000015_gene3646	1.061e-79	294.0	COG3267@1|root,COG3267@2|Bacteria,2GMRH@201174|Actinobacteria	201174|Actinobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2694210_1	1050202.KB913024_gene1746	6.615e-23	98.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2I12T@201174|Actinobacteria,408CD@622450|Actinopolysporales	201174|Actinobacteria	L	AAA domain	pcrA	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
SRR25158535_k127_2702018_2	1445613.JALM01000081_gene1025	2.613e-33	136.0	COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4DZIC@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
SRR25158535_k127_2702018_0	1123024.AUII01000036_gene3156	5.76e-180	574.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria,4E870@85010|Pseudonocardiales	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
SRR25158535_k127_2702018_1	1380370.JIBA01000015_gene379	8.798e-51	186.0	2CA7I@1|root,30E5G@2|Bacteria,2IJ78@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2721535_4	1122611.KB903939_gene407	1.498e-29	128.0	COG0454@1|root,COG0454@2|Bacteria,2IDJQ@201174|Actinobacteria,4EK87@85012|Streptosporangiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_2721535_7	680198.SCAB_51071	5.719e-15	85.0	COG0842@1|root,COG0842@2|Bacteria,2H7QX@201174|Actinobacteria	201174|Actinobacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2721535_2	1449976.KALB_760	1.745e-46	171.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4DXWB@85010|Pseudonocardiales	201174|Actinobacteria	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_2721535_8	1449976.KALB_760	5.058e-11	66.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4DXWB@85010|Pseudonocardiales	201174|Actinobacteria	U	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_2721535_0	909613.UO65_3308	1.57e-89	305.0	COG1396@1|root,COG1396@2|Bacteria,2GJBK@201174|Actinobacteria,4DZBX@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2721535_6	469371.Tbis_0235	1.595e-15	85.0	2E6IT@1|root,3315W@2|Bacteria,2HP20@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR25158535_k127_2721535_5	298653.Franean1_1329	3.415e-23	101.0	2E6IT@1|root,3315W@2|Bacteria,2GT51@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
SRR25158535_k127_2721535_1	263358.VAB18032_04770	1.344e-88	302.0	COG1396@1|root,COG1396@2|Bacteria,2GJBK@201174|Actinobacteria,4D91Z@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2721535_3	1236902.ANAS01000005_gene4962	6.195e-32	132.0	COG1309@1|root,COG1309@2|Bacteria,2IFXK@201174|Actinobacteria,4EMZW@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2721535_9	1161401.ASJA01000002_gene2567	2.557e-08	59.0	2DPU9@1|root,333E7@2|Bacteria,1N6Y7@1224|Proteobacteria,2UHW4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	ko:K22014	-	-	-	-	ko00000	-	-	-	-
SRR25158535_k127_2722852_3	1123319.AUBE01000005_gene196	9.963e-26	124.0	COG2315@1|root,COG2315@2|Bacteria,2II89@201174|Actinobacteria	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158535_k127_2722852_1	861299.J421_3248	2.102e-72	266.0	COG0438@1|root,COG0438@2|Bacteria,1ZSTJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2722852_0	253839.SSNG_06405	1.349e-85	295.0	COG2021@1|root,COG2021@2|Bacteria,2I3NA@201174|Actinobacteria	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SRR25158535_k127_2722852_2	1380390.JIAT01000010_gene4680	1.164e-48	176.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4CRGJ@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2726416_0	1121946.AUAX01000023_gene4242	2.022e-175	580.0	COG0577@1|root,COG0577@2|Bacteria,2GN4X@201174|Actinobacteria,4DAEZ@85008|Micromonosporales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
SRR25158535_k127_2726416_1	1449346.JQMO01000003_gene4916	1.159e-30	122.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,2M4P6@2063|Kitasatospora	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2734931_0	1089545.KB913037_gene847	4.832e-101	333.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4E4W8@85010|Pseudonocardiales	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
SRR25158535_k127_2741076_1	479432.Sros_1649	2.626e-135	437.0	COG0498@1|root,COG0498@2|Bacteria,2GJ5F@201174|Actinobacteria,4EGAS@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_2741076_3	479435.Kfla_5635	3.897e-20	96.0	COG1846@1|root,COG1846@2|Bacteria,2HZF0@201174|Actinobacteria,4DSHF@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158535_k127_2741076_0	105420.BBPO01000057_gene3501	2.67e-216	707.0	COG0477@1|root,COG0477@2|Bacteria,2GJ09@201174|Actinobacteria,2NH2M@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_2741076_2	1380393.JHVP01000002_gene1522	7.793e-59	216.0	COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4ESFG@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158535_k127_2747775_1	1111131.HMPREF1255_1651	5.185e-89	303.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4DPCH@85009|Propionibacteriales	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158535_k127_2747775_5	1380347.JNII01000006_gene1208	0.0002508	50.0	COG3794@1|root,COG3794@2|Bacteria,2H13T@201174|Actinobacteria,4EX0U@85013|Frankiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158535_k127_2747775_3	1120936.KB907211_gene263	1.128e-62	231.0	COG1309@1|root,COG1309@2|Bacteria,2GNBS@201174|Actinobacteria,4EK2F@85012|Streptosporangiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158535_k127_2747775_0	479432.Sros_4184	9.383e-129	420.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ENIC@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_2747775_2	479432.Sros_4183	9.819e-87	310.0	COG0842@1|root,COG0842@2|Bacteria,2IHJH@201174|Actinobacteria,4ENXS@85012|Streptosporangiales	201174|Actinobacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_27504_0	706587.Desti_5503	5.526e-83	307.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Spermine spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SRR25158535_k127_27504_2	324602.Caur_0190	3.885e-14	84.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SRR25158535_k127_27504_1	28444.JODQ01000002_gene4027	3.482e-68	240.0	COG0596@1|root,COG0596@2|Bacteria,2I32Y@201174|Actinobacteria,4ER3J@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158535_k127_2754741_0	298654.FraEuI1c_0746	4.411e-120	399.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4ERIC@85013|Frankiales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
SRR25158535_k127_2754741_1	1191523.MROS_0448	4.181e-18	87.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2761671_0	479432.Sros_5690	5.312e-143	459.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EHSR@85012|Streptosporangiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_2761671_2	1122609.AUGT01000011_gene3577	6.107e-101	357.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4DNUY@85009|Propionibacteriales	201174|Actinobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
SRR25158535_k127_2761671_1	113395.AXAI01000004_gene4583	1.656e-128	445.0	COG0683@1|root,COG0683@2|Bacteria,1N0MT@1224|Proteobacteria,2TUMI@28211|Alphaproteobacteria,3JS0N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,TAT_signal
SRR25158535_k127_2761671_3	1123024.AUII01000028_gene2491	1.043e-92	324.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4DXUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
SRR25158535_k127_2761671_4	1097668.BYI23_C010710	2.568e-82	276.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.39,1.2.1.8	ko:K00130,ko:K00146	ko00260,ko00360,ko00643,ko01100,ko01120,map00260,map00360,map00643,map01100,map01120	M00555	R02536,R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_2795912_2	1237500.ANBA01000009_gene1044	2.939e-05	48.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4EGXC@85012|Streptosporangiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_2795912_0	1122247.C731_2277	3.216e-40	157.0	COG0500@1|root,COG2226@2|Bacteria,2IGKC@201174|Actinobacteria,238UQ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_2795912_1	1116232.AHBF01000118_gene4342	8.284e-30	126.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2797721_2	926560.KE387027_gene964	2.129e-21	98.0	COG5516@1|root,COG5516@2|Bacteria,1WMR5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158535_k127_2797721_3	671143.DAMO_1037	4.795e-06	54.0	COG1135@1|root,COG1135@2|Bacteria	2|Bacteria	P	methionine transport	-	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Fer4,NIL
SRR25158535_k127_2797721_1	28444.JODQ01000010_gene3087	8.117e-69	246.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
SRR25158535_k127_2797721_0	1137269.AZWL01000029_gene4533	8.967e-141	451.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SRR25158535_k127_2797784_2	1380393.JHVP01000001_gene2406	1.883e-13	83.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4ERM9@85013|Frankiales	201174|Actinobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SRR25158535_k127_2797784_0	760568.Desku_3294	1.31e-137	449.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,2605P@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SRR25158535_k127_2797784_1	1120950.KB892708_gene4496	2.015e-26	108.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4DNQ8@85009|Propionibacteriales	201174|Actinobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SRR25158535_k127_2797836_0	1236902.ANAS01000019_gene4262	4.102e-106	354.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4EHH4@85012|Streptosporangiales	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SRR25158535_k127_2797836_2	1394178.AWOO02000003_gene2743	9.951e-47	170.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4EJCM@85012|Streptosporangiales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SRR25158535_k127_2797836_3	1121877.JQKF01000009_gene544	1.344e-44	162.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CN5R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SRR25158535_k127_2797836_1	1120950.KB892746_gene3613	5.991e-69	235.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4DN2A@85009|Propionibacteriales	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SRR25158535_k127_2798541_0	1137268.AZXF01000006_gene2032	1.398e-141	460.0	COG0579@1|root,COG0579@2|Bacteria,2GKFB@201174|Actinobacteria,4EH5V@85012|Streptosporangiales	201174|Actinobacteria	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_2798541_1	1121468.AUBR01000036_gene1298	3.701e-72	256.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42G77@68295|Thermoanaerobacterales	186801|Clostridia	D	tyrosine recombinase XerC	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158535_k127_2798541_2	1122180.Lokhon_02800	2.042e-38	162.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2P88C@245186|Loktanella	28211|Alphaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
SRR25158535_k127_2798541_3	1123354.AUDR01000011_gene1488	5.049e-27	115.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,1KSHB@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SRR25158535_k127_2798654_1	512565.AMIS_42480	2.275e-22	102.0	2E5WA@1|root,330KC@2|Bacteria,2GWSH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2798654_0	345341.KUTG_04850	8.595e-71	261.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
SRR25158535_k127_2798654_2	1136417.AZWE01000023_gene1202	0.0004732	49.0	COG2267@1|root,COG2267@2|Bacteria,2GJSU@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158535_k127_2798813_0	882083.SacmaDRAFT_4301	5.641e-199	628.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DYJK@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD3	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_2798813_1	35754.JNYJ01000037_gene4671	3.592e-89	304.0	COG3055@1|root,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4DFPE@85008|Micromonosporales	201174|Actinobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
SRR25158535_k127_2798813_2	1323361.JPOC01000016_gene1965	3.601e-06	61.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,4FTZ5@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
SRR25158535_k127_2800005_1	2045.KR76_09105	3.344e-13	72.0	COG3311@1|root,COG3311@2|Bacteria,2GR98@201174|Actinobacteria,4DS1Q@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_2800005_0	479431.Namu_1375	1.009e-29	134.0	COG0455@1|root,COG0455@2|Bacteria,2IARP@201174|Actinobacteria,4ERDT@85013|Frankiales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
SRR25158535_k127_2801555_1	426716.JOAJ01000002_gene2056	6.883e-113	374.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4FZVS@85025|Nocardiaceae	201174|Actinobacteria	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SRR25158535_k127_2801555_2	326427.Cagg_2683	1.815e-64	247.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,3754U@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
SRR25158535_k127_2801555_0	186497.PF0547	5.124e-174	557.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
SRR25158535_k127_2801555_4	644283.Micau_5868	1.584e-06	63.0	2E8UC@1|root,3334W@2|Bacteria,2GRUC@201174|Actinobacteria,4DFS6@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2801555_3	1380393.JHVP01000003_gene1048	4.99e-20	89.0	COG1915@1|root,COG1915@2|Bacteria,2GMEZ@201174|Actinobacteria,4EUTP@85013|Frankiales	201174|Actinobacteria	S	PFAM LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
SRR25158535_k127_2806533_4	1056816.JAFQ01000004_gene5567	5.94e-48	183.0	COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4FXZC@85025|Nocardiaceae	201174|Actinobacteria	IT	Lysylphosphatidylglycerol synthase TM region	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
SRR25158535_k127_2806533_0	1380347.JNII01000007_gene334	3.259e-189	611.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	-	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	Kdo,PAP2
SRR25158535_k127_2806533_3	1211815.CBYP010000050_gene561	2.257e-69	253.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4EVAF@85013|Frankiales	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
SRR25158535_k127_2806533_1	264732.Moth_0703	1.928e-88	306.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,42I51@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
SRR25158535_k127_2806533_2	1380356.JNIK01000001_gene2106	2.229e-78	282.0	COG4585@1|root,COG4585@2|Bacteria,2H756@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
SRR25158535_k127_2809612_1	414996.IL38_03010	5.458e-49	178.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,408BR@622450|Actinopolysporales	201174|Actinobacteria	L	Single-strand binding protein family	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
SRR25158535_k127_2809612_3	656024.FsymDg_4520	4.166e-28	121.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4ESZ0@85013|Frankiales	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SRR25158535_k127_2809612_0	351607.Acel_2130	1.351e-49	180.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4ESST@85013|Frankiales	201174|Actinobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SRR25158535_k127_2809612_2	1122611.KB903955_gene5552	7.606e-38	156.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,4EH2H@85012|Streptosporangiales	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
SRR25158535_k127_2811520_1	1128421.JAGA01000002_gene1215	1.558e-52	194.0	COG0116@1|root,COG0116@2|Bacteria,2NQIY@2323|unclassified Bacteria	2|Bacteria	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
SRR25158535_k127_2811520_0	479435.Kfla_2975	2.058e-107	368.0	COG0596@1|root,COG0596@2|Bacteria,2GMYM@201174|Actinobacteria,4DTGY@85009|Propionibacteriales	201174|Actinobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SRR25158535_k127_2812755_7	526225.Gobs_3753	1.243e-12	70.0	COG1848@1|root,COG1848@2|Bacteria,2IQB5@201174|Actinobacteria,4EWC0@85013|Frankiales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158535_k127_2812755_2	406552.NJ7G_0659	1.481e-67	245.0	COG1619@1|root,arCOG04676@2157|Archaea,2XTDE@28890|Euryarchaeota,23TNV@183963|Halobacteria	183963|Halobacteria	V	proteins, homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
SRR25158535_k127_2812755_5	1463856.JOHY01000002_gene1447	2.097e-22	102.0	COG1670@1|root,COG1670@2|Bacteria,2INDG@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_3
SRR25158535_k127_2812755_10	391625.PPSIR1_02601	0.0008015	48.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	AhpC-TSA,DUF5011,MRJP,NHL,SGL,Thioredoxin_8
SRR25158535_k127_2812755_9	1133849.O3I_021515	6.828e-11	67.0	COG0346@1|root,COG0346@2|Bacteria,2I8Q5@201174|Actinobacteria,4FYHT@85025|Nocardiaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Aminoglyc_resit
SRR25158535_k127_2812755_8	1123024.AUII01000005_gene2291	1.975e-11	77.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
SRR25158535_k127_2812755_1	1380390.JIAT01000011_gene2492	1.063e-76	261.0	COG0262@1|root,COG0262@2|Bacteria,2GJU5@201174|Actinobacteria	201174|Actinobacteria	H	Bifunctional deaminase-reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_2812755_4	479432.Sros_2638	4.665e-52	195.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158535_k127_2812755_0	1120950.KB892757_gene6609	5.116e-215	677.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DU7F@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2812755_3	1121946.AUAX01000015_gene5945	5.57e-55	196.0	COG3795@1|root,COG3795@2|Bacteria,2IIV2@201174|Actinobacteria,4DFEQ@85008|Micromonosporales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
SRR25158535_k127_2812755_6	1116472.MGMO_7c00210	4.192e-15	75.0	COG3211@1|root,COG3211@2|Bacteria,1R7E2@1224|Proteobacteria,1SCSQ@1236|Gammaproteobacteria,1XGF9@135618|Methylococcales	135618|Methylococcales	S	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
SRR25158535_k127_2813715_3	471852.Tcur_2041	1.865e-49	183.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria,4EQYY@85012|Streptosporangiales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_2813715_1	414996.IL38_17810	4.532e-72	261.0	COG1309@1|root,COG1309@2|Bacteria,2GM0H@201174|Actinobacteria,409VA@622450|Actinopolysporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2813715_0	67352.JODS01000002_gene1409	6.368e-159	506.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158535_k127_2813715_4	392499.Swit_3583	8.85e-49	190.0	COG0665@1|root,COG0665@2|Bacteria,1R4U7@1224|Proteobacteria,2U26T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	D-amino acid	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_2813715_2	471852.Tcur_2041	6.076e-59	218.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria,4EQYY@85012|Streptosporangiales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_2814115_2	1040982.AXAL01000011_gene1109	2.867e-26	114.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,2U9TG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_2814115_1	208439.AJAP_05390	9.727e-33	132.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_2814115_0	749927.AMED_7933	4.427e-41	162.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4E7AU@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158535_k127_2815282_3	465541.ATCJ01000005_gene7427	2.846e-12	72.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_2815282_4	711393.AYRX01000083_gene4724	1.365e-09	68.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2IEKD@201174|Actinobacteria	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_2815282_0	1122138.AQUZ01000001_gene1614	8.037e-188	595.0	COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,2GPKD@201174|Actinobacteria,4DRG1@85009|Propionibacteriales	201174|Actinobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GerE
SRR25158535_k127_2815282_1	1122138.AQUZ01000001_gene1613	4.493e-67	232.0	COG0662@1|root,COG0662@2|Bacteria,2IEY0@201174|Actinobacteria,4DVK8@85009|Propionibacteriales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2816040_3	1068980.ARVW01000001_gene857	1.425e-28	117.0	COG2141@1|root,COG2141@2|Bacteria,2HVKH@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2816040_2	164757.Mjls_0699	2.062e-95	320.0	COG1073@1|root,COG1073@2|Bacteria,2I9HJ@201174|Actinobacteria,237IR@1762|Mycobacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SRR25158535_k127_2816040_4	110319.CF8_4068	2.521e-26	126.0	COG1409@1|root,COG1409@2|Bacteria,2GP0C@201174|Actinobacteria,4DS7R@85009|Propionibacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
SRR25158535_k127_2816040_0	469383.Cwoe_1045	1.508e-184	590.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SRR25158535_k127_2816040_1	479433.Caci_7728	6.709e-165	538.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_2820513_2	324602.Caur_3769	8.841e-13	79.0	COG2152@1|root,COG3055@1|root,COG3266@1|root,COG5624@1|root,COG2152@2|Bacteria,COG3055@2|Bacteria,COG3266@2|Bacteria,COG5624@2|Bacteria,2G86G@200795|Chloroflexi,376E1@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SRR25158535_k127_2820513_1	1236902.ANAS01000007_gene3967	4.157e-21	95.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158535_k127_2820513_0	1210046.B277_03345	6.191e-62	232.0	COG3103@1|root,COG3103@2|Bacteria,2IGZN@201174|Actinobacteria	201174|Actinobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2821866_0	1449069.JMLO01000037_gene2731	1.37e-68	239.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria,4G1QC@85025|Nocardiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,Glyoxalase
SRR25158535_k127_2821866_2	1169161.KB897713_gene6700	3.056e-14	80.0	COG1309@1|root,COG1309@2|Bacteria,2ICWK@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2821866_1	1123023.JIAI01000010_gene8427	8.315e-50	186.0	COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria,4E4J6@85010|Pseudonocardiales	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_2823951_2	1380390.JIAT01000013_gene47	3.773e-74	255.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,4CR3N@84995|Rubrobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_2823951_0	105425.BBPL01000014_gene2800	2.064e-117	392.0	COG3842@1|root,COG3842@2|Bacteria,2H2JF@201174|Actinobacteria,2NFU0@228398|Streptacidiphilus	201174|Actinobacteria	E	TOBE domain	modC	-	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
SRR25158535_k127_2823951_1	1121946.AUAX01000036_gene1878	2.383e-102	343.0	COG4149@1|root,COG4149@2|Bacteria,2GJFB@201174|Actinobacteria,4DAIP@85008|Micromonosporales	201174|Actinobacteria	P	molybdate ABC transporter, inner membrane subunit	modB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017,ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,BPD_transp_1,TOBE
SRR25158535_k127_2823951_3	1463820.JOGW01000005_gene3361	5.127e-64	239.0	COG0725@1|root,COG0725@2|Bacteria,2GMPF@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
SRR25158535_k127_2823951_4	298654.FraEuI1c_7019	2.179e-42	158.0	COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4ET46@85013|Frankiales	201174|Actinobacteria	H	DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,MerR,TOBE
SRR25158535_k127_2823951_5	298653.Franean1_5232	1.348e-19	94.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_2824129_15	675635.Psed_6422	2.615e-34	139.0	COG3897@1|root,COG3897@2|Bacteria,2GTAU@201174|Actinobacteria	201174|Actinobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
SRR25158535_k127_2824129_21	44060.JODL01000044_gene4008	3.558e-07	60.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2824129_5	1128421.JAGA01000003_gene2767	7.753e-87	312.0	COG3538@1|root,COG3538@2|Bacteria	2|Bacteria	G	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
SRR25158535_k127_2824129_8	1268072.PSAB_07265	1.509e-59	216.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4IPNE@91061|Bacilli,2760S@186822|Paenibacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158535_k127_2824129_14	1123052.AUDF01000005_gene1157	7.734e-41	171.0	COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4FMNF@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
SRR25158535_k127_2824129_12	1120950.KB892757_gene6413	1.622e-42	169.0	COG1175@1|root,COG1175@2|Bacteria,2IHI4@201174|Actinobacteria,4DWRE@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
SRR25158535_k127_2824129_9	1306406.ASHX01000001_gene3986	2.851e-52	201.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1,SBP_bac_8
SRR25158535_k127_2824129_6	1268072.PSAB_07250	6.92e-63	236.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,4HA0U@91061|Bacilli,270G3@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
SRR25158535_k127_2824129_20	1033743.CAES01000015_gene2377	1.966e-11	77.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,26Z0J@186822|Paenibacillaceae	91061|Bacilli	K	UTRA	frlR3	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158535_k127_2824129_16	1459636.NTE_00536	2.926e-29	121.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SRR25158535_k127_2824129_17	1223543.GP2_003_01050	6.106e-26	112.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158535_k127_2824129_13	35754.JNYJ01000038_gene4896	3.731e-41	164.0	COG0546@1|root,COG0546@2|Bacteria,2GNCU@201174|Actinobacteria,4DC5V@85008|Micromonosporales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2,Hydrolase_like
SRR25158535_k127_2824129_7	649831.L083_7332	3.346e-61	225.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	waaD	-	2.4.1.56	ko:K00713,ko:K03280	ko00540,ko01100,map00540,map01100	M00080	R01996	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4,GT9	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2824129_3	33876.JNXY01000021_gene4782	1.146e-101	346.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2824129_19	33876.JNXY01000021_gene4781	3.78e-20	94.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SRR25158535_k127_2824129_4	33876.JNXY01000021_gene4780	1.034e-89	325.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4DBD5@85008|Micromonosporales	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
SRR25158535_k127_2824129_0	710686.Mycsm_01466	2.906e-143	492.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,2I3VK@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2,RibD_C
SRR25158535_k127_2824129_10	543632.JOJL01000043_gene3768	5.191e-52	188.0	COG3631@1|root,COG3631@2|Bacteria,2IQSN@201174|Actinobacteria,4DGNR@85008|Micromonosporales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158535_k127_2824129_1	1463825.JNXC01000024_gene5043	4.159e-137	447.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4E9XQ@85010|Pseudonocardiales	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_2824129_2	1463887.KL590056_gene7488	3.113e-133	436.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
SRR25158535_k127_2824129_11	1108045.GORHZ_206_00230	6.128e-51	191.0	COG3548@1|root,COG3548@2|Bacteria,2GRE3@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
SRR25158535_k127_2824129_18	211114.JOEF01000029_gene7850	4.999e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,2GVC0@201174|Actinobacteria,4E6XT@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SRR25158535_k127_2827678_4	926550.CLDAP_33840	7.99e-32	127.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SRR25158535_k127_2827678_1	1313172.YM304_26780	1.664e-193	622.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4CMTE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
SRR25158535_k127_2827678_0	1242864.D187_004550	1.997e-242	758.0	COG1509@1|root,COG1509@2|Bacteria,1R8HT@1224|Proteobacteria,43DMX@68525|delta/epsilon subdivisions,2X6DS@28221|Deltaproteobacteria,2YUSV@29|Myxococcales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	kamA1	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C
SRR25158535_k127_2827678_2	562970.Btus_2110	4.96e-61	217.0	COG2452@1|root,COG2452@2|Bacteria,1V387@1239|Firmicutes,4IRW1@91061|Bacilli,279R1@186823|Alicyclobacillaceae	91061|Bacilli	L	Resolvase, N terminal domain	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	MerR,Resolvase
SRR25158535_k127_2827678_3	867903.ThesuDRAFT_01019	3.569e-47	194.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_2829050_3	390989.JOEG01000009_gene1046	2.303e-60	211.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,4D9B0@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SRR25158535_k127_2829050_1	469371.Tbis_1233	4.175e-84	294.0	COG1120@1|root,COG1120@2|Bacteria,2IA4F@201174|Actinobacteria,4E0AK@85010|Pseudonocardiales	201174|Actinobacteria	HP	ABC-type cobalamin Fe3 -siderophore transport system, ATPase component	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SRR25158535_k127_2829050_2	1229780.BN381_420011	1.222e-63	237.0	COG2109@1|root,COG2109@2|Bacteria,2GNJQ@201174|Actinobacteria,3UXDI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
SRR25158535_k127_2829050_5	1313172.YM304_11580	1.472e-40	166.0	COG2087@1|root,COG2087@2|Bacteria,2GM8Q@201174|Actinobacteria,4CND7@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobP	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
SRR25158535_k127_2829050_0	1313172.YM304_11570	2.34e-93	322.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4CN1T@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
SRR25158535_k127_2829050_4	1313172.YM304_11560	1.315e-43	179.0	COG0368@1|root,COG0368@2|Bacteria,2HGZT@201174|Actinobacteria,4CP01@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
SRR25158535_k127_2829050_7	1521187.JPIM01000053_gene2953	3.96e-10	70.0	COG0823@1|root,COG0823@2|Bacteria,2GAJ0@200795|Chloroflexi,376FZ@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SRR25158535_k127_2829050_6	479434.Sthe_2947	1.188e-34	136.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi	200795|Chloroflexi	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158535_k127_2830809_6	1449069.JMLO01000031_gene240	2.22e-10	62.0	COG0596@1|root,COG2114@1|root,COG0596@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria,4FUZX@85025|Nocardiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Guanylate_cyc
SRR25158535_k127_2830809_1	1048339.KB913029_gene972	1.489e-173	549.0	COG0491@1|root,COG0491@2|Bacteria,2HTU1@201174|Actinobacteria,4EUGY@85013|Frankiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_2830809_0	1068978.AMETH_4196	6.212e-219	710.0	COG0654@1|root,COG0654@2|Bacteria,2GKIN@201174|Actinobacteria,4DY4H@85010|Pseudonocardiales	201174|Actinobacteria	CH	2-polyprenyl-6-methoxyphenol	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
SRR25158535_k127_2830809_4	83332.Rv2132	2.722e-21	95.0	2DF58@1|root,2ZQII@2|Bacteria,2GVR9@201174|Actinobacteria,23BPX@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158535_k127_2830809_2	1121933.AUHH01000007_gene3216	1.257e-50	186.0	COG1848@1|root,COG1848@2|Bacteria,2IJ89@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158535_k127_2830809_5	498848.TaqDRAFT_4776	7.268e-16	90.0	COG3740@1|root,COG4388@1|root,COG3740@2|Bacteria,COG4388@2|Bacteria,1WN2I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Mu-like prophage I protein	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_Pro
SRR25158535_k127_2830809_3	309801.trd_0162	6.9e-31	133.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi,27Y62@189775|Thermomicrobia	189775|Thermomicrobia	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
SRR25158535_k127_284023_0	1304865.JAGF01000001_gene1275	1.755e-93	317.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4F0QR@85016|Cellulomonadaceae	201174|Actinobacteria	D	Belongs to the SEDS family	rodA	GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SRR25158535_k127_284023_1	479437.Elen_3041	1.356e-63	240.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CUGE@84998|Coriobacteriia	84998|Coriobacteriia	T	phosphatase 2C	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
SRR25158535_k127_284023_3	469371.Tbis_0050	5.539e-25	119.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4E2PP@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SRR25158535_k127_284023_2	269800.Tfu_3060	1.789e-46	179.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4EFW3@85012|Streptosporangiales	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
SRR25158535_k127_2840405_3	710111.FraQA3DRAFT_4808	5.139e-13	73.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4EUBH@85013|Frankiales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SRR25158535_k127_2840405_2	44060.JODL01000013_gene3931	5.408e-41	163.0	COG5516@1|root,COG5516@2|Bacteria,2IFNZ@201174|Actinobacteria	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158535_k127_2840405_1	1122611.KB903952_gene6033	4.254e-55	197.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4EJ6E@85012|Streptosporangiales	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
SRR25158535_k127_2840405_0	314345.SPV1_03553	2.736e-55	202.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria	1224|Proteobacteria	KL	Helicase	yoaA	GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
SRR25158535_k127_2845564_0	561175.KB894093_gene4266	1.197e-65	239.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4EGXF@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_2845564_1	1179773.BN6_53490	1.442e-27	114.0	COG3696@1|root,COG3696@2|Bacteria,2H303@201174|Actinobacteria,4EF0N@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SRR25158535_k127_2854765_6	656024.FsymDg_0048	1.239e-30	124.0	COG0484@1|root,COG0484@2|Bacteria,2GIXJ@201174|Actinobacteria,4EV37@85013|Frankiales	201174|Actinobacteria	O	Replication initiator protein	repSA1	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2854765_8	33876.JNXY01000031_gene3147	9.707e-11	66.0	2EQWD@1|root,31TJG@2|Bacteria,2HUZ0@201174|Actinobacteria,4DGDG@85008|Micromonosporales	201174|Actinobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_2854765_3	882082.SaccyDRAFT_4367	3.954e-77	272.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158535_k127_2854765_0	1236902.ANAS01000005_gene4939	7.445e-142	466.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4EH2Z@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
SRR25158535_k127_2854765_7	351607.Acel_2106	1.581e-24	119.0	COG1196@1|root,COG1196@2|Bacteria,2IMXX@201174|Actinobacteria,4ET89@85013|Frankiales	201174|Actinobacteria	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
SRR25158535_k127_2854765_4	240015.ACP_0087	1.709e-69	254.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia	204432|Acidobacteriia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SRR25158535_k127_2854765_2	1146883.BLASA_0244	5.425e-105	365.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria,4EU8D@85013|Frankiales	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SRR25158535_k127_2854765_9	1449976.KALB_8042	3.943e-07	54.0	2E5D5@1|root,33055@2|Bacteria,2IR7Y@201174|Actinobacteria,4E6T9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2854765_1	1415166.NONO_c38250	3.384e-105	356.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4FW27@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_2854765_5	1121946.AUAX01000019_gene7750	8.281e-31	125.0	COG0596@1|root,COG0596@2|Bacteria,2IFCI@201174|Actinobacteria,4DC31@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158535_k127_2858705_4	1121877.JQKF01000009_gene498	9.228e-16	79.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158535_k127_2858705_3	369723.Strop_3838	5.931e-33	138.0	2DHRC@1|root,32U9K@2|Bacteria,2IJX8@201174|Actinobacteria,4DDEE@85008|Micromonosporales	201174|Actinobacteria	S	Family of unknown function (DUF5319)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5319
SRR25158535_k127_2858705_1	561175.KB894093_gene4318	1.742e-69	245.0	COG0560@1|root,COG0560@2|Bacteria,2GJW9@201174|Actinobacteria,4EGP9@85012|Streptosporangiales	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	serB1	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158535_k127_2858705_0	518766.Rmar_1858	2.619e-138	450.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SRR25158535_k127_2858705_2	1267534.KB906755_gene4395	1.719e-40	155.0	COG1004@1|root,COG1004@2|Bacteria,3Y3GR@57723|Acidobacteria,2JHU0@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SRR25158535_k127_286354_2	196162.Noca_0367	2.755e-07	59.0	2EGB2@1|root,33A2X@2|Bacteria,2HZDA@201174|Actinobacteria,4DS7Y@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_286354_1	710111.FraQA3DRAFT_2691	4.773e-37	157.0	COG1611@1|root,COG1611@2|Bacteria,2IN1B@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158535_k127_286354_0	365528.KB891285_gene5048	3.066e-127	417.0	COG0514@1|root,COG1205@1|root,COG0514@2|Bacteria,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,4ERHU@85013|Frankiales	201174|Actinobacteria	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
SRR25158535_k127_2865120_4	1538644.KO02_19125	7.557e-09	68.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
SRR25158535_k127_2865120_5	298653.Franean1_4182	1.136e-06	61.0	COG3404@1|root,COG3404@2|Bacteria,2IIRF@201174|Actinobacteria,4EVRR@85013|Frankiales	201174|Actinobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
SRR25158535_k127_2865120_3	1121468.AUBR01000045_gene1801	8.672e-72	271.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,42EU0@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Formiminotransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
SRR25158535_k127_2865120_2	1121468.AUBR01000045_gene1802	6.869e-101	373.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158535_k127_2865120_0	266117.Rxyl_0583	1.83e-263	822.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4CRM0@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
SRR25158535_k127_2865120_1	266117.Rxyl_0576	1.577e-162	527.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4CPAC@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM phenylalanine histidine ammonia-lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158535_k127_287232_1	543632.JOJL01000042_gene4561	1.633e-12	70.0	COG0474@1|root,COG0474@2|Bacteria,2I458@201174|Actinobacteria	201174|Actinobacteria	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_287232_0	994479.GL877878_gene2948	1.74e-286	887.0	COG5421@1|root,COG5421@2|Bacteria,2GKNQ@201174|Actinobacteria,4E23E@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_2877919_0	419947.MRA_1470	6.035e-265	852.0	COG0719@1|root,COG1372@1|root,COG0719@2|Bacteria,COG1372@2|Bacteria,2GKCZ@201174|Actinobacteria,23407@1762|Mycobacteriaceae	201174|Actinobacteria	O	assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158535_k127_2877919_2	266117.Rxyl_0168	1.089e-70	267.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SRR25158535_k127_2877919_4	55952.BU52_26710	5.894e-26	120.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
SRR25158535_k127_2877919_1	1122611.KB903971_gene2713	2.564e-103	348.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4EGEE@85012|Streptosporangiales	201174|Actinobacteria	O	ATPases associated with a variety of cellular activities	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SRR25158535_k127_2877919_3	765420.OSCT_1487	2.134e-29	130.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,3766K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SRR25158535_k127_2882124_0	1122611.KB903996_gene7634	5.936e-107	354.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4EJVU@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2882124_1	43354.JOIJ01000002_gene4184	3.31e-105	346.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4DYKR@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158535_k127_2887048_1	543632.JOJL01000119_gene275	9.178e-30	130.0	COG3267@1|root,COG3267@2|Bacteria,2IA4V@201174|Actinobacteria	201174|Actinobacteria	U	Type II secretory pathway component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR25158535_k127_2887048_0	525368.HMPREF0591_4472	6.941e-93	321.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria,236H8@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase, catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,Mu-transpos_C,rve
SRR25158535_k127_2907068_6	110319.CF8_3666	0.0006879	45.0	COG3371@1|root,COG3371@2|Bacteria,2I044@201174|Actinobacteria,4DVJR@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158535_k127_2907068_4	1429046.RR21198_1254	1.727e-47	183.0	2CK59@1|root,32VV2@2|Bacteria,2I7N7@201174|Actinobacteria,4G9UM@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2907068_5	471852.Tcur_2812	2.333e-34	140.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4EK6U@85012|Streptosporangiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_2907068_1	926560.KE387025_gene4131	1.796e-107	367.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_2907068_2	926560.KE387025_gene4132	2.338e-86	294.0	COG2085@1|root,COG2085@2|Bacteria,1WMWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	F420_oxidored
SRR25158535_k127_2907068_3	404589.Anae109_3656	7.45e-63	221.0	COG1309@1|root,COG1309@2|Bacteria,1RADD@1224|Proteobacteria,43AQM@68525|delta/epsilon subdivisions,2X64I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_2907068_0	106370.Francci3_3042	8.558e-263	826.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria,4EUWH@85013|Frankiales	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, middle domain	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
SRR25158535_k127_2912475_3	35754.JNYJ01000025_gene8964	2.168e-05	56.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4DH6E@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_2912475_2	35754.JNYJ01000025_gene8964	2.244e-84	288.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4DH6E@85008|Micromonosporales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_2912475_0	1120950.KB892743_gene3128	1.724e-132	428.0	COG2141@1|root,COG2141@2|Bacteria,2GKRH@201174|Actinobacteria,4DNHJ@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_2912475_4	1068980.ARVW01000001_gene7457	0.0003366	51.0	COG1396@1|root,COG1396@2|Bacteria,2GJXM@201174|Actinobacteria,4E52Z@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_2912475_1	1122611.KB903996_gene7643	1.072e-87	292.0	COG0395@1|root,COG0395@2|Bacteria,2GJPF@201174|Actinobacteria,4ENK7@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
SRR25158535_k127_291448_0	273068.TTE0463	3.643e-122	399.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,42F24@68295|Thermoanaerobacterales	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
SRR25158535_k127_291448_1	351607.Acel_1240	3.219e-104	345.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4ERYA@85013|Frankiales	201174|Actinobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158535_k127_291448_3	196162.Noca_2494	1.41e-24	108.0	2E3JK@1|root,32YHZ@2|Bacteria,2GS0Y@201174|Actinobacteria,4DRQ0@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_291448_2	1121468.AUBR01000002_gene641	3.598e-70	250.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,42FDN@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM Glycosyl transferase, family 3	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SRR25158535_k127_2922136_2	292459.STH2483	2.397e-30	124.0	COG2151@1|root,COG2151@2|Bacteria,1V3QG@1239|Firmicutes,2528Q@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158535_k127_2922136_1	869210.Marky_1368	6.503e-59	220.0	COG3396@1|root,COG3396@2|Bacteria,1WI5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158535_k127_2922136_3	479434.Sthe_2568	9.708e-20	100.0	COG3460@1|root,COG3460@2|Bacteria	2|Bacteria	Q	phenylacetate catabolic process	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
SRR25158535_k127_2922136_0	869210.Marky_1366	9.552e-74	251.0	COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158535_k127_2923709_7	1184609.KILIM_128_00010	2.173e-35	141.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4F6S0@85018|Dermatophilaceae	201174|Actinobacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SRR25158535_k127_2923709_5	326424.FRAAL3438	3.538e-64	236.0	COG0061@1|root,COG0061@2|Bacteria,2I8RN@201174|Actinobacteria,4EVE3@85013|Frankiales	201174|Actinobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
SRR25158535_k127_2923709_4	644283.Micau_2405	4.907e-79	276.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4DAFA@85008|Micromonosporales	201174|Actinobacteria	J	FtsJ-like methyltransferase	tlyA	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SRR25158535_k127_2923709_11	1122182.KB903838_gene3977	9.663e-07	61.0	COG3937@1|root,COG3937@2|Bacteria,2ISFA@201174|Actinobacteria,4DEZR@85008|Micromonosporales	201174|Actinobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
SRR25158535_k127_2923709_9	106370.Francci3_3162	7.041e-12	77.0	COG3255@1|root,COG3255@2|Bacteria,2IM6I@201174|Actinobacteria,4ETJH@85013|Frankiales	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SRR25158535_k127_2923709_2	351607.Acel_0827	1.587e-82	282.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria,4ESF4@85013|Frankiales	201174|Actinobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SRR25158535_k127_2923709_6	1146883.BLASA_2477	7.17e-49	194.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4ESEC@85013|Frankiales	201174|Actinobacteria	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SRR25158535_k127_2923709_8	1380347.JNII01000005_gene2765	3.665e-16	93.0	COG0457@1|root,COG0457@2|Bacteria,2IQ48@201174|Actinobacteria,4ESZG@85013|Frankiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SRR25158535_k127_2923709_3	656024.FsymDg_3259	1.385e-80	284.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SRR25158535_k127_2923709_1	68260.JOAY01000057_gene5333	8.954e-89	302.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria	201174|Actinobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_2923709_10	504472.Slin_1809	3.161e-11	78.0	COG1983@1|root,COG1983@2|Bacteria,4NS0M@976|Bacteroidetes,47QMV@768503|Cytophagia	976|Bacteroidetes	KT	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
SRR25158535_k127_2923709_0	1380347.JNII01000005_gene3057	2.459e-217	695.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	-	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	Kdo,PAP2
SRR25158535_k127_2924110_3	1449044.JMLE01000005_gene735	4.495e-96	327.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,1W8C2@1268|Micrococcaceae	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SRR25158535_k127_2924110_1	760568.Desku_0658	5.159e-107	385.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,260M6@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
SRR25158535_k127_2924110_2	479433.Caci_1298	1.612e-101	351.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	etfA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SRR25158535_k127_2924110_5	1122182.KB903834_gene5715	5.373e-84	302.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4D8MJ@85008|Micromonosporales	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SRR25158535_k127_2924110_6	264732.Moth_1935	1.167e-70	261.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,42F43@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Galactose-1-phosphate uridyl transferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,DUF4931,GalP_UDP_tr_C,GalP_UDP_transf
SRR25158535_k127_2924110_4	1236902.ANAS01000041_gene4365	3.512e-94	316.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4EH13@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_2924110_7	68199.JNZO01000050_gene1559	4.311e-19	97.0	COG0296@1|root,COG0296@2|Bacteria,2IMRT@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2924110_0	2002.JOEQ01000004_gene2707	1.188e-148	477.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria,4EHJD@85012|Streptosporangiales	201174|Actinobacteria	I	Methylmalonyl-CoA mutase	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158535_k127_2924631_1	1068978.AMETH_5809	6.002e-101	332.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4DXQW@85010|Pseudonocardiales	201174|Actinobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158535_k127_2924631_7	861299.J421_3206	1.103e-15	79.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
SRR25158535_k127_2924631_5	58123.JOFJ01000008_gene402	2.888e-52	199.0	COG1737@1|root,COG1737@2|Bacteria,2GMG0@201174|Actinobacteria,4EG56@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	bact-PGI_C
SRR25158535_k127_2924631_4	997346.HMPREF9374_0362	2.261e-61	222.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27BBV@186824|Thermoactinomycetaceae	91061|Bacilli	F	Phosphorylase superfamily	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158535_k127_2924631_0	298654.FraEuI1c_6056	6.775e-179	572.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
SRR25158535_k127_2924631_6	1313172.YM304_12540	6.676e-42	167.0	COG1714@1|root,COG1714@2|Bacteria,2H4MP@201174|Actinobacteria	201174|Actinobacteria	A	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158535_k127_2924631_2	1313172.YM304_12530	2.057e-91	312.0	COG1300@1|root,COG1300@2|Bacteria,2GJTG@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
SRR25158535_k127_2924631_3	356851.JOAN01000006_gene305	9.981e-81	289.0	COG1028@1|root,COG1028@2|Bacteria,2IFUD@201174|Actinobacteria,4D8PP@85008|Micromonosporales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	ywfD	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
SRR25158535_k127_2924631_8	67257.JODR01000017_gene4546	3.682e-06	48.0	COG1721@1|root,COG1721@2|Bacteria,2GK9A@201174|Actinobacteria	201174|Actinobacteria	S	protein some members contain a von Willebrand factor type A vWA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
SRR25158535_k127_2926156_0	479434.Sthe_2436	4.911e-123	400.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,27XRX@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158535_k127_2926156_1	324602.Caur_0502	8.735e-28	130.0	COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia	32061|Chloroflexia	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SRR25158535_k127_2926156_2	1487953.JMKF01000066_gene3796	3.679e-12	79.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria,1H765@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Glucosamine-6-phosphate isomerases 6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SRR25158535_k127_292729_1	471852.Tcur_1191	2.336e-12	79.0	2E6WZ@1|root,331GF@2|Bacteria,2IFC6@201174|Actinobacteria,4EK7D@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_292729_2	1219035.NT2_02_01320	3.435e-05	52.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,2K616@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
SRR25158535_k127_292729_0	1122138.AQUZ01000019_gene8140	1.694e-119	390.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4DP46@85009|Propionibacteriales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
SRR25158535_k127_2927661_0	1121946.AUAX01000006_gene3453	1.132e-302	940.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4DAJ3@85008|Micromonosporales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SRR25158535_k127_2927661_5	2002.JOEQ01000004_gene2829	1.749e-103	357.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4EHRB@85012|Streptosporangiales	201174|Actinobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SRR25158535_k127_2927661_8	251221.35211636	2.886e-47	173.0	COG1970@1|root,COG1970@2|Bacteria,1G829@1117|Cyanobacteria	1117|Cyanobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
SRR25158535_k127_2927661_16	1205753.A989_13029	1.857e-05	51.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1X798@135614|Xanthomonadales	135614|Xanthomonadales	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158535_k127_2927661_13	1305732.JAGG01000001_gene987	1.523e-13	74.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria,4FNQ0@85023|Microbacteriaceae	201174|Actinobacteria	CO	Redoxin	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
SRR25158535_k127_2927661_11	1120950.KB892757_gene6511	9.058e-19	88.0	COG1830@1|root,COG1830@2|Bacteria,2HPYZ@201174|Actinobacteria,4DW96@85009|Propionibacteriales	201174|Actinobacteria	G	DeoC/LacD family aldolase	-	-	4.1.2.56	ko:K18287	-	-	-	-	ko00000,ko01000	-	-	-	DeoC
SRR25158535_k127_2927661_15	35754.JNYJ01000001_gene7449	9.467e-07	60.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	ant1	-	2.7.7.47	ko:K00984	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2
SRR25158535_k127_2927661_10	1227457.C451_14640	2.388e-41	171.0	COG0697@1|root,arCOG00271@2157|Archaea,2XT64@28890|Euryarchaeota,23TZT@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_2927661_1	710111.FraQA3DRAFT_5074	2.973e-181	576.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4ERUX@85013|Frankiales	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SRR25158535_k127_2927661_4	1382356.JQMP01000004_gene110	1.625e-120	430.0	COG0151@1|root,COG0151@2|Bacteria,2G5ZE@200795|Chloroflexi,27XZU@189775|Thermomicrobia	189775|Thermomicrobia	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
SRR25158535_k127_2927661_14	105420.BBPO01000008_gene2641	3.444e-11	76.0	COG2320@1|root,COG2320@2|Bacteria,2HG2U@201174|Actinobacteria,2NN9W@228398|Streptacidiphilus	201174|Actinobacteria	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
SRR25158535_k127_2927661_9	340177.Cag_0286	6.254e-44	165.0	COG0041@1|root,COG0041@2|Bacteria,1FDYI@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SRR25158535_k127_2927661_3	582515.KR51_00027750	4.292e-124	411.0	COG0015@1|root,COG0015@2|Bacteria,1G07M@1117|Cyanobacteria	1117|Cyanobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158535_k127_2927661_6	234267.Acid_5250	2.166e-94	338.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria	57723|Acidobacteria	F	PFAM SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SRR25158535_k127_2927661_2	1051632.TPY_2517	3.924e-177	574.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248QX@186801|Clostridia	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_2927661_7	469383.Cwoe_4718	2.761e-58	211.0	COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4CQBM@84995|Rubrobacteria	84995|Rubrobacteria	G	Phosphoglycerate mutase family	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
SRR25158535_k127_2927661_12	395965.Msil_0120	1.017e-15	88.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2TU68@28211|Alphaproteobacteria,3N9WF@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SRR25158535_k127_2930257_4	1048339.KB913029_gene4723	1.795e-25	113.0	COG0388@1|root,COG0388@2|Bacteria,2H03Y@201174|Actinobacteria,4EVT7@85013|Frankiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SRR25158535_k127_2930257_5	68170.KL590535_gene3759	1.838e-20	104.0	COG5401@1|root,COG5401@2|Bacteria,2H4HT@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158535_k127_2930257_7	1380386.JIAW01000015_gene6548	1.449e-09	70.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158535_k127_2930257_3	710686.Mycsm_05235	2.42e-30	132.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,232Z7@1762|Mycobacteriaceae	201174|Actinobacteria	IT	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158535_k127_2930257_2	1961.JOAK01000001_gene3055	3.634e-33	137.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
SRR25158535_k127_2930257_6	1127134.NOCYR_1764	1.242e-18	88.0	2ER8X@1|root,33IUI@2|Bacteria,2IRAS@201174|Actinobacteria,4G57Q@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
SRR25158535_k127_2930257_0	1123322.KB904710_gene82	1.565e-184	604.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
SRR25158535_k127_2930257_1	469383.Cwoe_3251	1.302e-55	201.0	COG1372@1|root,COG1533@1|root,COG1372@2|Bacteria,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158535_k127_2934548_0	390989.JOEG01000007_gene596	9.536e-93	312.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
SRR25158535_k127_2934548_3	471852.Tcur_2997	2.687e-59	213.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4EHF4@85012|Streptosporangiales	201174|Actinobacteria	G	Ribulose-phosphate 3 epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SRR25158535_k127_2934548_1	1283287.KB822576_gene3476	1.637e-77	287.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria,4DP4E@85009|Propionibacteriales	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
SRR25158535_k127_2934548_2	561175.KB894098_gene5471	4.778e-73	260.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4EHUK@85012|Streptosporangiales	201174|Actinobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SRR25158535_k127_2934548_4	477641.MODMU_1727	5.813e-25	108.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4ESF2@85013|Frankiales	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158535_k127_2934642_0	42256.RradSPS_2536	7.273e-80	276.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_2934642_1	263358.VAB18032_25750	7.209e-18	92.0	2E8C8@1|root,332QW@2|Bacteria,2IP3X@201174|Actinobacteria,4DEPD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2939067_0	1120936.KB907211_gene254	2.899e-70	245.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria,4EG2S@85012|Streptosporangiales	201174|Actinobacteria	P	TrkA-C domain	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158535_k127_2939067_1	479431.Namu_3757	1.78e-58	221.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria,4ERNZ@85013|Frankiales	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
SRR25158535_k127_2939067_3	471852.Tcur_1708	1.926e-10	70.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria,4EJMR@85012|Streptosporangiales	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2939067_2	215803.DB30_3268	4.408e-15	80.0	COG1547@1|root,COG1547@2|Bacteria,1P75K@1224|Proteobacteria,432ZJ@68525|delta/epsilon subdivisions,2WXIJ@28221|Deltaproteobacteria,2Z233@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
SRR25158535_k127_2939067_4	658086.HMPREF0994_06163	1.758e-08	65.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
SRR25158535_k127_2939067_5	1274524.BSONL12_08767	8.619e-08	54.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,4HCQ3@91061|Bacilli,1ZEBR@1386|Bacillus	91061|Bacilli	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	KdpD,Usp
SRR25158535_k127_2939595_0	263358.VAB18032_13900	2.197e-98	325.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4DBXC@85008|Micromonosporales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158535_k127_2939595_1	1479237.JMLY01000001_gene2635	3.142e-65	241.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1RP2N@1236|Gammaproteobacteria,469C2@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Alpha amylase, catalytic domain	treZ	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158535_k127_2939595_2	1141662.OOA_00990	0.0001496	44.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158535_k127_2940918_4	383372.Rcas_3769	2.624e-47	179.0	COG1028@1|root,COG1611@1|root,COG1028@2|Bacteria,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SRR25158535_k127_2940918_6	35754.JNYJ01000008_gene3290	5.879e-14	81.0	COG3393@1|root,COG3393@2|Bacteria,2IF2P@201174|Actinobacteria,4D8RE@85008|Micromonosporales	201174|Actinobacteria	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
SRR25158535_k127_2940918_2	43354.JOIJ01000002_gene4389	3.63e-70	247.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4DYC5@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2773c	DapB_C,DapB_N
SRR25158535_k127_2940918_0	1313172.YM304_25950	9.521e-172	584.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
SRR25158535_k127_2940918_5	1283283.ATXA01000023_gene262	6.858e-29	134.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4ESG6@85013|Frankiales	201174|Actinobacteria	K	Sigma-70, region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_2940918_3	1382356.JQMP01000003_gene2130	2.636e-59	230.0	COG2159@1|root,COG2159@2|Bacteria,2G6EZ@200795|Chloroflexi,27YN4@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158535_k127_2940918_1	479432.Sros_2916	6.031e-120	391.0	COG0174@1|root,COG0174@2|Bacteria,2GJ83@201174|Actinobacteria,4ENPD@85012|Streptosporangiales	201174|Actinobacteria	E	Glutamine synthetase N-terminal domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
SRR25158535_k127_2942605_0	390989.JOEG01000009_gene1253	2.458e-177	567.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4DA3Y@85008|Micromonosporales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158535_k127_2942605_7	436229.JOEH01000005_gene3001	7.159e-20	99.0	COG0736@1|root,COG0736@2|Bacteria,2IQF6@201174|Actinobacteria,2NIMC@228398|Streptacidiphilus	201174|Actinobacteria	I	4'-phosphopantetheinyl transferase superfamily	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SRR25158535_k127_2942605_1	477974.Daud_0471	7.07e-81	294.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
SRR25158535_k127_2942605_2	1157635.KB892002_gene4182	4.572e-74	274.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SRR25158535_k127_2942605_4	1394178.AWOO02000003_gene2686	4.472e-54	210.0	COG2267@1|root,COG2267@2|Bacteria,2GMCK@201174|Actinobacteria,4EFMQ@85012|Streptosporangiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158535_k127_2942605_3	1123504.JQKD01000027_gene4123	1.309e-68	244.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria,4ABW8@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	PFAM peptidase S58 DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
SRR25158535_k127_2942605_8	1246995.AFR_40150	3.478e-07	55.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria,4DG2K@85008|Micromonosporales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158535_k127_2942605_5	479434.Sthe_0942	5.881e-53	194.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,27XM8@189775|Thermomicrobia	189775|Thermomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158535_k127_2942605_6	868595.Desca_0462	3.76e-32	131.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SRR25158535_k127_2950962_3	1068978.AMETH_1661	1.3e-45	166.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4E1BJ@85010|Pseudonocardiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SRR25158535_k127_2950962_2	926560.KE387023_gene1501	3.277e-93	344.0	COG0524@1|root,COG0524@2|Bacteria,1WKDK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158535_k127_2950962_1	42256.RradSPS_3033	3.322e-141	456.0	COG0240@1|root,COG0240@2|Bacteria,2HYHZ@201174|Actinobacteria,4CQSG@84995|Rubrobacteria	84995|Rubrobacteria	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SRR25158535_k127_2950962_0	926550.CLDAP_26850	1.399e-159	520.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5	ko:K00848,ko:K00851,ko:K00854,ko:K00862	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158535_k127_2950962_4	471852.Tcur_2331	1.137e-11	65.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EH24@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
SRR25158535_k127_2953728_4	365528.KB891252_gene5640	1.083e-44	171.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4ERM4@85013|Frankiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158535_k127_2953728_5	1288083.AUKR01000012_gene572	3.099e-38	147.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SRR25158535_k127_2953728_0	222534.KB893739_gene1390	3.788e-135	444.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,4ERPF@85013|Frankiales	201174|Actinobacteria	C	geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,Trp_halogenase
SRR25158535_k127_2953728_3	219305.MCAG_03174	2.535e-64	228.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4DAGF@85008|Micromonosporales	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SRR25158535_k127_2953728_2	365528.KB891252_gene5666	2.176e-78	291.0	COG0755@1|root,COG0755@2|Bacteria,2GJR1@201174|Actinobacteria,4ESE9@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SRR25158535_k127_2953728_1	1236902.ANAS01000019_gene4145	1.162e-84	298.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4EHFG@85012|Streptosporangiales	201174|Actinobacteria	O	ResB-like family	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158535_k127_2955891_2	1122223.KB890697_gene1132	4.04e-64	223.0	COG0277@1|root,COG0277@2|Bacteria,1WKVA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_2955891_5	194867.ALBQ01000004_gene3477	0.0005072	51.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2955891_1	1068980.ARVW01000001_gene7443	1.202e-121	396.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_2955891_0	1123024.AUII01000021_gene11	4.612e-125	405.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4E3S9@85010|Pseudonocardiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158535_k127_2955891_4	1206720.BAFQ01000082_gene2120	1.626e-18	85.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4FUV9@85025|Nocardiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_2957513_2	40571.JOEA01000014_gene2046	7.685e-18	93.0	2B36U@1|root,31VUU@2|Bacteria,2GW94@201174|Actinobacteria,4E6YV@85010|Pseudonocardiales	201174|Actinobacteria	S	ClpX C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-C4_ClpX
SRR25158535_k127_2957513_1	1150864.MILUP08_42361	2.883e-89	304.0	COG1309@1|root,COG1309@2|Bacteria,2GYYS@201174|Actinobacteria,4DEP4@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158535_k127_2957513_0	653045.Strvi_0621	8.211e-107	355.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_2959216_1	632518.Calow_0805	2.803e-14	80.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,42F9X@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
SRR25158535_k127_2959216_0	526225.Gobs_0610	1.53e-55	211.0	COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4ESBK@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase III, delta'	holB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SRR25158535_k127_2959774_0	251221.35215005	1.31e-225	709.0	COG3211@1|root,COG3211@2|Bacteria,1G1TG@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Bacterial protein of	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
SRR25158535_k127_2959774_1	469371.Tbis_2230	4.975e-101	340.0	COG1319@1|root,COG1319@2|Bacteria,2GP37@201174|Actinobacteria,4EEM6@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
SRR25158535_k127_296499_2	1172185.KB911511_gene3141	6.704e-26	109.0	2CA7I@1|root,30E5G@2|Bacteria,2IJ78@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_296499_0	1172188.KB911824_gene3394	5.059e-213	682.0	COG3055@1|root,COG3055@2|Bacteria,2IA06@201174|Actinobacteria,4FIGW@85021|Intrasporangiaceae	201174|Actinobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_296499_3	1121272.KB903290_gene4612	1.401e-09	63.0	29F3Q@1|root,3021G@2|Bacteria,2HDYA@201174|Actinobacteria,4DKNK@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_296499_1	1150864.MILUP08_44102	1.772e-85	283.0	COG0702@1|root,COG0702@2|Bacteria,2HVU1@201174|Actinobacteria,4D8HF@85008|Micromonosporales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SRR25158535_k127_2965052_0	981369.JQMJ01000001_gene6648	9.233e-43	160.0	COG3415@1|root,COG3415@2|Bacteria,2H6YF@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2965052_2	1048834.TC41_1206	5.109e-06	55.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HUAQ@91061|Bacilli	91061|Bacilli	L	Recombinase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_2965052_1	420324.KI911994_gene8036	8.252e-30	127.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria	1224|Proteobacteria	L	Resolvase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_296803_3	1386089.N865_14320	6.054e-70	247.0	COG2755@1|root,COG2755@2|Bacteria,2GMDE@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
SRR25158535_k127_296803_7	443598.AUFA01000038_gene5069	6.432e-47	173.0	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,2UAPG@28211|Alphaproteobacteria,3JYFP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	MA20_43515	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_296803_13	479432.Sros_0849	0.0009163	43.0	COG1073@1|root,COG1073@2|Bacteria,2I4WN@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
SRR25158535_k127_296803_6	1206726.BAFV01000126_gene6728	3.633e-51	184.0	COG4319@1|root,COG4319@2|Bacteria,2IRQ1@201174|Actinobacteria,4G96K@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158535_k127_296803_8	68170.KL590492_gene6165	2.758e-37	146.0	2BNCR@1|root,32H0E@2|Bacteria,2HRIE@201174|Actinobacteria,4EASX@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
SRR25158535_k127_296803_5	1299327.I546_6183	3.936e-61	218.0	COG1848@1|root,COG1848@2|Bacteria,2IJ89@201174|Actinobacteria,239HU@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SRR25158535_k127_296803_12	1299327.I546_6182	5.387e-22	97.0	2DSMH@1|root,33GPM@2|Bacteria,2GR8G@201174|Actinobacteria,23BKG@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_296803_4	1120950.KB892708_gene4507	1.919e-62	223.0	COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria,4DUVR@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease V	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SRR25158535_k127_296803_10	1214101.BN159_2302	1.25e-29	135.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_296803_0	196162.Noca_4966	8.415e-168	558.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_296803_9	2002.JOEQ01000038_gene4184	4.158e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,2GQRD@201174|Actinobacteria,4EHRF@85012|Streptosporangiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
SRR25158535_k127_296803_1	345341.KUTG_08045	3.94e-119	396.0	COG0500@1|root,COG2226@2|Bacteria,2I3SA@201174|Actinobacteria,4EF8K@85010|Pseudonocardiales	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158535_k127_296803_11	1120949.KB903356_gene8767	1.179e-26	115.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4DEPX@85008|Micromonosporales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
SRR25158535_k127_296803_2	264732.Moth_2009	1.059e-117	392.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,42EXF@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158535_k127_2970467_0	219305.MCAG_04341	1.797e-117	406.0	COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,4DBTG@85008|Micromonosporales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
SRR25158535_k127_2970467_1	35754.JNYJ01000009_gene1838	2.583e-80	275.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4DAEI@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_298557_0	748727.CLJU_c32630	7.894e-29	128.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,36IJE@31979|Clostridiaceae	186801|Clostridia	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
SRR25158535_k127_298557_1	405948.SACE_3736	3.776e-22	104.0	2E8C8@1|root,332QW@2|Bacteria,2GVKT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_298840_7	1463841.JOIR01000011_gene2705	1.509e-08	68.0	COG3266@1|root,COG3266@2|Bacteria,2GN4E@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_298840_5	29306.JOBE01000045_gene6127	5.706e-28	124.0	2DS0G@1|root,33DYY@2|Bacteria,2GKA4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_298840_6	525909.Afer_0202	5.129e-16	81.0	2E3QT@1|root,31FNG@2|Bacteria,2HGTF@201174|Actinobacteria,4CNV3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_298840_0	1123024.AUII01000003_gene3424	8.357e-97	329.0	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria,4DXEP@85010|Pseudonocardiales	201174|Actinobacteria	D	ATPase involved in chromosome	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
SRR25158535_k127_298840_2	1394178.AWOO02000006_gene3475	1.11e-71	256.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria,4EPPC@85012|Streptosporangiales	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SLT,SLT_2
SRR25158535_k127_298840_9	266117.Rxyl_3075	8.978e-07	54.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria	201174|Actinobacteria	E	dehydrogenase	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SRR25158535_k127_298840_1	1229780.BN381_10220	1.546e-93	329.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,3UX9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
SRR25158535_k127_298840_8	1265310.CCBD010000088_gene4496	2.129e-08	66.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,232XZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_298840_3	1549858.MC45_16640	1.586e-52	190.0	28PSM@1|root,2ZCE4@2|Bacteria,1RBR6@1224|Proteobacteria,2V0GH@28211|Alphaproteobacteria,2K9CV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_298840_4	1549858.MC45_16645	4.034e-31	126.0	28IZD@1|root,2Z8WU@2|Bacteria,1NEGQ@1224|Proteobacteria,2UZGH@28211|Alphaproteobacteria,2K8TY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_299055_2	1210046.B277_11960	8.346e-111	367.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_299055_4	313589.JNB_03725	1.145e-76	277.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_299055_0	1385518.N798_14505	3.55e-202	676.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria,4FK2X@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
SRR25158535_k127_299055_5	1274.HX89_08070	1.485e-60	221.0	COG0457@1|root,COG0457@2|Bacteria,2H220@201174|Actinobacteria,1ZWF0@145357|Dermacoccaceae	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
SRR25158535_k127_299055_6	1380347.JNII01000005_gene3443	7.04e-39	158.0	2B1K4@1|root,32S9C@2|Bacteria,2I2R4@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3068)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3068
SRR25158535_k127_299055_3	1120936.KB907209_gene1349	5.491e-102	360.0	28HIC@1|root,2Z7TU@2|Bacteria,2GNK5@201174|Actinobacteria,4EHFZ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_299055_1	1136417.AZWE01000049_gene4744	2.578e-122	404.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria,4D9G4@85008|Micromonosporales	201174|Actinobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_2995735_17	1463887.KL589996_gene7909	3.957e-08	65.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD,FixH
SRR25158535_k127_2995735_16	479434.Sthe_3008	3.429e-10	65.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi,27XZB@189775|Thermomicrobia	200795|Chloroflexi	P	Copper resistance protein CopC	-	-	-	-	-	-	-	-	-	-	-	-	CopC,CopD
SRR25158535_k127_2995735_18	47716.JOFH01000014_gene5988	4.77e-07	56.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158535_k127_2995735_12	1128421.JAGA01000002_gene1633	1.053e-27	121.0	arCOG08811@1|root,32UTS@2|Bacteria,2NR80@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2995735_9	269800.Tfu_2625	5.491e-60	213.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4EG7R@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158535_k127_2995735_13	526225.Gobs_1982	4.119e-23	108.0	2CHUP@1|root,33EJR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2178
SRR25158535_k127_2995735_14	446466.Cfla_0408	1.866e-22	97.0	COG1476@1|root,COG1476@2|Bacteria,2GQIU@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
SRR25158535_k127_2995735_2	263358.VAB18032_18675	4.916e-113	371.0	COG2890@1|root,COG2890@2|Bacteria,2I3YD@201174|Actinobacteria,4DMFE@85008|Micromonosporales	201174|Actinobacteria	J	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158535_k127_2995735_10	1120949.KB903328_gene9117	3.086e-51	190.0	COG3247@1|root,COG3247@2|Bacteria,2GSMH@201174|Actinobacteria,4DFMZ@85008|Micromonosporales	201174|Actinobacteria	S	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
SRR25158535_k127_2995735_7	1122182.KB903836_gene4748	1.482e-72	262.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4DAFF@85008|Micromonosporales	201174|Actinobacteria	L	5'-3' exonuclease	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158535_k127_2995735_6	1120949.KB903326_gene3159	2.33e-76	266.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_2995735_4	43759.JNWK01000010_gene4794	1.058e-101	351.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
SRR25158535_k127_2995735_3	1394178.AWOO02000109_gene5733	1.23e-107	361.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,4EHZ3@85012|Streptosporangiales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
SRR25158535_k127_2995735_0	1394178.AWOO02000109_gene5734	3.213e-198	632.0	COG0687@1|root,COG0687@2|Bacteria,2I10F@201174|Actinobacteria,4EJAK@85012|Streptosporangiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
SRR25158535_k127_2995735_1	2002.JOEQ01000024_gene196	3.384e-137	455.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EFFE@85012|Streptosporangiales	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
SRR25158535_k127_2995735_8	690850.Desaf_2977	9.17e-62	229.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria,2M9ST@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SRR25158535_k127_2995735_11	502025.Hoch_4423	1.375e-43	166.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2Z32M@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SRR25158535_k127_2995735_5	994479.GL877881_gene6280	1.853e-84	290.0	COG2339@1|root,COG2339@2|Bacteria,2I9NJ@201174|Actinobacteria,4DZ23@85010|Pseudonocardiales	201174|Actinobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SRR25158535_k127_302378_9	443143.GM18_0489	0.0008703	43.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
SRR25158535_k127_302378_8	671143.DAMO_2813	9.862e-37	148.0	COG1102@1|root,COG1102@2|Bacteria,2NRB0@2323|unclassified Bacteria	2|Bacteria	F	Cytidylate kinase-like family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
SRR25158535_k127_302378_3	1385521.N803_07845	1.859e-51	188.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4FERH@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158535_k127_302378_5	369723.Strop_2380	7.217e-48	177.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4D9DY@85008|Micromonosporales	201174|Actinobacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SRR25158535_k127_302378_7	929712.KI912613_gene4803	1.301e-41	175.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SRR25158535_k127_302378_1	760568.Desku_2533	4.398e-53	205.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,261CK@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158535_k127_302378_6	1121272.KB903289_gene4244	5.003e-46	182.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4D9KI@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
SRR25158535_k127_302378_0	469371.Tbis_1693	4.627e-55	197.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4E2ZJ@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SRR25158535_k127_302378_4	298653.Franean1_4998	1.535e-49	179.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4ESYX@85013|Frankiales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
SRR25158535_k127_302378_2	1120950.KB892823_gene520	5.385e-53	209.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4DN8K@85009|Propionibacteriales	201174|Actinobacteria	V	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SRR25158535_k127_3027887_2	222534.KB893739_gene1323	1.879e-73	250.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4ERNA@85013|Frankiales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158535_k127_3027887_3	269800.Tfu_2625	1.715e-57	214.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4EG7R@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158535_k127_3027887_1	1009370.ALO_03501	5.259e-86	301.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
SRR25158535_k127_3027887_0	1049564.TevJSym_ac01750	1.417e-133	433.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J5NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
SRR25158535_k127_3027887_5	1121272.KB903250_gene2983	6.575e-38	142.0	COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4DF19@85008|Micromonosporales	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SRR25158535_k127_3027887_6	1403948.Q618_VCMC00003G0093	8.71e-14	75.0	COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4D6P0@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SRR25158535_k127_3027887_4	298654.FraEuI1c_6202	6.689e-43	159.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4ESIQ@85013|Frankiales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SRR25158535_k127_3048383_0	526225.Gobs_3984	2.617e-71	254.0	COG0262@1|root,COG0262@2|Bacteria,2ING3@201174|Actinobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_3048383_3	1121272.KB903291_gene3438	1.935e-39	161.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DCN3@85008|Micromonosporales	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
SRR25158535_k127_3048383_1	1089545.KB913037_gene7859	5.324e-67	238.0	COG0428@1|root,COG0428@2|Bacteria,2IBHZ@201174|Actinobacteria,4E2MD@85010|Pseudonocardiales	201174|Actinobacteria	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
SRR25158535_k127_3048383_2	1033730.CAHG01000015_gene810	9.436e-48	178.0	COG2409@1|root,COG2409@2|Bacteria,2GIRQ@201174|Actinobacteria,4DNWE@85009|Propionibacteriales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_3050398_7	795359.TOPB45_0396	6.047e-16	81.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	metF3	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158535_k127_3050398_3	1283283.ATXA01000001_gene417	1.603e-63	226.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158535_k127_3050398_6	405948.SACE_4737	2.182e-19	104.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,2ICDR@201174|Actinobacteria,4E6UB@85010|Pseudonocardiales	201174|Actinobacteria	I	SNARE associated Golgi protein	-	-	3.6.1.27	ko:K03975,ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
SRR25158535_k127_3050398_0	1137271.AZUM01000006_gene432	6.67e-126	422.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria,4E06F@85010|Pseudonocardiales	201174|Actinobacteria	I	Phospholipase D Active site motif	-	-	3.1.4.4	ko:K01115	ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000,ko04131	-	-	-	PLDc,PLDc_2
SRR25158535_k127_3050398_5	710686.Mycsm_01609	3.463e-40	163.0	COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,234W1@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SRR25158535_k127_3050398_4	1869.MB27_05485	1.641e-50	203.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4D8NE@85008|Micromonosporales	201174|Actinobacteria	I	Diacylglycerol kinase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
SRR25158535_k127_3050398_2	710686.Mycsm_01608	5.118e-83	292.0	COG1295@1|root,COG1295@2|Bacteria,2GM6P@201174|Actinobacteria,236CI@1762|Mycobacteriaceae	201174|Actinobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SRR25158535_k127_3050398_1	298654.FraEuI1c_0967	2.209e-92	307.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4EREC@85013|Frankiales	201174|Actinobacteria	G	Trehalose synthase	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
SRR25158535_k127_3053112_0	390989.JOEG01000009_gene998	1.733e-141	464.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DA92@85008|Micromonosporales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
SRR25158535_k127_3053112_2	452652.KSE_34240	4.706e-108	377.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,2M2GT@2063|Kitasatospora	201174|Actinobacteria	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
SRR25158535_k127_3053112_6	700508.D174_24885	3.344e-51	191.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,234B7@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcription factor CarD	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SRR25158535_k127_3053112_9	871963.Desdi_0407	1.56e-38	156.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,261YY@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
SRR25158535_k127_3053112_8	94624.Bpet1696	7.517e-41	157.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,3T3SA@506|Alcaligenaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
SRR25158535_k127_3053112_1	1121472.AQWN01000015_gene1352	2.329e-134	443.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2609V@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158535_k127_3053112_5	644966.Tmar_2313	4.485e-58	223.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WD6D@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158535_k127_3053112_4	1120950.KB892790_gene2056	3.651e-64	236.0	COG0582@1|root,COG0582@2|Bacteria,2I9QS@201174|Actinobacteria,4DTV4@85009|Propionibacteriales	201174|Actinobacteria	K	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158535_k127_3053112_10	1048339.KB913029_gene1274	1.046e-06	54.0	COG1476@1|root,COG1476@2|Bacteria,2I3A6@201174|Actinobacteria	201174|Actinobacteria	K	peptide deformylase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_3053112_7	1237500.ANBA01000008_gene374	5.776e-51	198.0	COG1813@1|root,COG1813@2|Bacteria,2I39C@201174|Actinobacteria,4ER6U@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_3053112_3	1394178.AWOO02000056_gene770	8.279e-72	246.0	COG0452@1|root,COG0452@2|Bacteria,2GP82@201174|Actinobacteria,4ENUX@85012|Streptosporangiales	201174|Actinobacteria	H	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
SRR25158535_k127_3053202_3	1476876.JOJO01000026_gene2007	3.453e-26	114.0	COG3631@1|root,COG3631@2|Bacteria,2IIFS@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158535_k127_3053202_4	1089551.KE386572_gene2332	6.798e-20	91.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,4BRRA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158535_k127_3053202_1	1283299.AUKG01000001_gene2810	1.276e-52	193.0	COG0122@1|root,COG0122@2|Bacteria,2HGA7@201174|Actinobacteria,4CQF8@84995|Rubrobacteria	84995|Rubrobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SRR25158535_k127_3053202_0	455632.SGR_6081	4.601e-195	633.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_3053202_2	471852.Tcur_0667	4.413e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2GPI5@201174|Actinobacteria,4EK80@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_3053202_5	1299327.I546_4071	2.158e-16	79.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,2329S@1762|Mycobacteriaceae	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SRR25158535_k127_3054017_1	543632.JOJL01000002_gene8238	1.635e-89	308.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4DAVA@85008|Micromonosporales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158535_k127_3054017_0	266117.Rxyl_2413	8.927e-120	400.0	COG3387@1|root,COG3387@2|Bacteria,2ICV9@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3054387_2	1121946.AUAX01000001_gene2335	8.855e-114	376.0	COG0001@1|root,COG0001@2|Bacteria,2HBVS@201174|Actinobacteria,4D95U@85008|Micromonosporales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_3054387_0	309801.trd_A0452	6.483e-137	450.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27YSW@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SRR25158535_k127_3054387_1	1122604.JONR01000007_gene2894	1.916e-115	390.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,1SFF8@1236|Gammaproteobacteria,1XDF0@135614|Xanthomonadales	135614|Xanthomonadales	IT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158535_k127_3054387_3	543632.JOJL01000013_gene9440	2.511e-45	167.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DDFZ@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_305589_0	43354.JOIJ01000010_gene2539	5.59e-104	345.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4DZI2@85010|Pseudonocardiales	201174|Actinobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SRR25158535_k127_305589_2	1394178.AWOO02000003_gene2729	2.311e-48	182.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4EIUJ@85012|Streptosporangiales	201174|Actinobacteria	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SRR25158535_k127_305589_4	1229203.KI301992_gene2083	1.292e-14	83.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,3UWZX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Ribosomal protein L30p/L7e	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SRR25158535_k127_305589_1	1123319.AUBE01000006_gene3268	1.842e-73	253.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SRR25158535_k127_305589_3	1370125.AUWT01000024_gene5467	5.561e-32	127.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,23980@1762|Mycobacteriaceae	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SRR25158535_k127_3058247_1	469371.Tbis_1706	1.012e-52	198.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4DYFK@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007	4.2.1.113,6.2.1.26	ko:K01911,ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030,R04031	RC00004,RC00014,RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_3058247_0	219305.MCAG_04305	1.951e-130	425.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4DHNE@85008|Micromonosporales	201174|Actinobacteria	H	Enoyl-CoA hydratase/isomerase	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_3058247_2	408672.NBCG_01014	1.805e-26	111.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4DNAI@85009|Propionibacteriales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158535_k127_3059713_4	1120949.KB903295_gene2225	3.183e-26	125.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D96C@85008|Micromonosporales	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,GerE,HTH_31,NB-ARC,TPR_12,Trans_reg_C
SRR25158535_k127_3059713_1	1160137.KB907307_gene2255	5.923e-90	313.0	COG3486@1|root,COG3486@2|Bacteria,2I991@201174|Actinobacteria,4FXSI@85025|Nocardiaceae	201174|Actinobacteria	Q	L-lysine 6-monooxygenase (NADPH-requiring)	mbtG	GO:0003674,GO:0003824,GO:0004497,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009237,GO:0009712,GO:0009987,GO:0016491,GO:0016701,GO:0016703,GO:0016705,GO:0016709,GO:0018958,GO:0019184,GO:0019290,GO:0019540,GO:0019748,GO:0034641,GO:0040007,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044550,GO:0047091,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901615	-	ko:K04793	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	K_oxygenase
SRR25158535_k127_3059713_5	1298863.AUEP01000022_gene1867	2.313e-17	89.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158535_k127_3059713_0	525368.HMPREF0591_1327	1.525e-114	394.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,2382Y@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_3059713_2	1108045.GORHZ_242_00030	1.305e-80	273.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria	201174|Actinobacteria	L	resolvase	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
SRR25158535_k127_3059713_3	882086.SacxiDRAFT_2254	2.37e-57	205.0	COG2220@1|root,COG2220@2|Bacteria,2GNHK@201174|Actinobacteria,4E33I@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase of beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
SRR25158535_k127_3061387_0	1123023.JIAI01000009_gene1167	3.743e-187	594.0	COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4DZXK@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
SRR25158535_k127_3061387_1	1463861.JNXE01000016_gene7262	4.884e-72	253.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_3061387_2	1449353.JQMQ01000005_gene5697	1.083e-59	213.0	COG4119@1|root,COG4119@2|Bacteria,2IM6D@201174|Actinobacteria	201174|Actinobacteria	L	Pfam NUDIX	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_3061387_3	471852.Tcur_0089	1.033e-42	168.0	COG0819@1|root,COG0819@2|Bacteria,2IADR@201174|Actinobacteria,4EGM8@85012|Streptosporangiales	201174|Actinobacteria	K	TENA/THI-4/PQQC family	-	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
SRR25158535_k127_3062428_0	446470.Snas_1978	1.17e-204	645.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EZWJ@85014|Glycomycetales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SRR25158535_k127_3062428_6	1122609.AUGT01000009_gene3341	2.815e-17	83.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4DRYR@85009|Propionibacteriales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_3062428_4	419947.MRA_2578	1.353e-38	151.0	COG2402@1|root,COG2402@2|Bacteria,2H9NW@201174|Actinobacteria	201174|Actinobacteria	S	toxic component of a	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SRR25158535_k127_3062428_3	356851.JOAN01000008_gene2972	4.223e-58	210.0	COG1309@1|root,COG1309@2|Bacteria,2GP3D@201174|Actinobacteria,4DD5T@85008|Micromonosporales	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158535_k127_3062428_2	471853.Bcav_3189	3.201e-61	231.0	28UEY@1|root,33GYE@2|Bacteria,2GY2N@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3062428_5	471853.Bcav_3190	6.075e-38	145.0	COG1695@1|root,COG1695@2|Bacteria,2GU31@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_3062428_1	246196.MSMEI_0640	1.137e-145	469.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria,236RV@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
SRR25158535_k127_3064187_1	710111.FraQA3DRAFT_4279	1.828e-52	194.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4ESSJ@85013|Frankiales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
SRR25158535_k127_3064187_3	1122939.ATUD01000008_gene2505	3.564e-18	98.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4CPJ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
SRR25158535_k127_3064187_6	1122609.AUGT01000007_gene1410	3.966e-06	59.0	2DRKZ@1|root,33C8D@2|Bacteria,2HZFK@201174|Actinobacteria,4DSKX@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3064187_0	1229172.JQFA01000004_gene1627	2.659e-86	298.0	COG4447@1|root,COG4447@2|Bacteria,1GAGV@1117|Cyanobacteria,1HF4J@1150|Oscillatoriales	1117|Cyanobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SRR25158535_k127_3064187_4	743718.Isova_0351	2.791e-12	74.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4F4U6@85017|Promicromonosporaceae	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_3064187_2	1394178.AWOO02000053_gene8110	6.312e-33	131.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4EK71@85012|Streptosporangiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158535_k127_3065380_0	298653.Franean1_7278	1.703e-106	368.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
SRR25158535_k127_3065380_2	28444.JODQ01000017_gene6511	1.745e-24	119.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4EKKE@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158535_k127_3065380_1	479433.Caci_5300	3.818e-26	113.0	2E61P@1|root,333YK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3065450_1	1123320.KB889675_gene3979	1.984e-145	479.0	COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria	201174|Actinobacteria	L	dead DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
SRR25158535_k127_3065450_0	1048339.KB913029_gene3309	0.0	1365.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4ES2Q@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E1	kgd	-	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SRR25158535_k127_3065450_2	1123319.AUBE01000004_gene616	1.336e-23	110.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158535_k127_3065848_0	345341.KUTG_07540	4.03e-118	396.0	COG3385@1|root,COG3385@2|Bacteria,2H68X@201174|Actinobacteria,4EAUY@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158535_k127_3065848_1	1343740.M271_39330	1.035e-24	104.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_Tnp_Tc3_2,rve_3
SRR25158535_k127_3065848_2	749414.SBI_08578	2.422e-10	65.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_32,rve,rve_3
SRR25158535_k127_3069044_0	1158050.KB895478_gene2702	6.567e-96	325.0	COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,1W8PU@1268|Micrococcaceae	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158535_k127_3069044_1	1134445.AJJM01000185_gene4061	3.103e-73	259.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	pdtaS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2,PAS_4
SRR25158535_k127_3071447_3	469371.Tbis_1730	3.242e-49	187.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158535_k127_3071447_4	1476583.DEIPH_ctg011orf0142	2.355e-37	153.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
SRR25158535_k127_3071447_6	656024.FsymDg_4316	2.638e-25	119.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4ESG1@85013|Frankiales	201174|Actinobacteria	K	PFAM Cyclic nucleotide-binding	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158535_k127_3071447_1	1382356.JQMP01000003_gene1688	3.101e-72	258.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_3071447_2	28444.JODQ01000001_gene2278	1.455e-67	244.0	COG2129@1|root,COG2129@2|Bacteria,2GMTQ@201174|Actinobacteria,4EHDC@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158535_k127_3071447_5	665577.JH993790_gene3716	2.451e-30	124.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria	201174|Actinobacteria	I	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
SRR25158535_k127_3071447_0	42256.RradSPS_1289	5.06e-98	346.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4CPDY@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SRR25158535_k127_3073315_2	1869.MB27_30450	2.729e-55	206.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria	201174|Actinobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
SRR25158535_k127_3073315_1	929712.KI912613_gene4125	4.197e-89	314.0	COG2141@1|root,COG2141@2|Bacteria,2ID60@201174|Actinobacteria,4CTIG@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_3073315_3	298655.KI912266_gene3795	1.111e-52	196.0	COG0824@1|root,COG0824@2|Bacteria,2IMQK@201174|Actinobacteria,4EWAR@85013|Frankiales	201174|Actinobacteria	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3073315_0	1108045.GORHZ_247_00370	4.305e-233	724.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM selenium-binding protein	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
SRR25158535_k127_3081095_3	585531.HMPREF0063_12561	7.256e-16	87.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4DN8S@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_3081095_4	1463934.JOCF01000018_gene3979	3.006e-11	75.0	2EGC7@1|root,33A40@2|Bacteria,2HEC9@201174|Actinobacteria	201174|Actinobacteria	S	Trp biosynthesis associated, transmembrane protein, oprn chp	-	-	-	-	-	-	-	-	-	-	-	-	Trp_oprn_chp
SRR25158535_k127_3081095_1	33876.JNXY01000044_gene1841	1.04e-150	493.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4D8F7@85008|Micromonosporales	201174|Actinobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SRR25158535_k127_3081095_2	1122182.KB903833_gene5151	2.154e-34	153.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4DDD9@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
SRR25158535_k127_3081095_0	1366050.N234_06785	6.928e-166	541.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2VKIR@28216|Betaproteobacteria,1K20Q@119060|Burkholderiaceae	28216|Betaproteobacteria	E	NAD-glutamate dehydrogenase	gdhB	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
SRR25158535_k127_3082001_1	1463825.JNXC01000021_gene7273	1.966e-106	366.0	COG4585@1|root,COG4585@2|Bacteria,2GMMU@201174|Actinobacteria,4DYS4@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
SRR25158535_k127_3082001_2	1121946.AUAX01000027_gene7946	2.346e-71	257.0	COG1073@1|root,COG1073@2|Bacteria,2GJ10@201174|Actinobacteria,4DEF9@85008|Micromonosporales	201174|Actinobacteria	S	Alpha/beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_8
SRR25158535_k127_3082001_0	1120950.KB892751_gene6796	3.639e-134	439.0	COG1835@1|root,COG1835@2|Bacteria,2GN56@201174|Actinobacteria,4DS19@85009|Propionibacteriales	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SRR25158535_k127_3085147_6	446471.Xcel_0820	3.027e-10	74.0	COG3266@1|root,COG3266@2|Bacteria,2GN4E@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
SRR25158535_k127_3085147_4	591167.Sfla_2930	5.028e-17	90.0	2DS0G@1|root,33DYY@2|Bacteria,2GKA4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3085147_3	525909.Afer_0202	2.511e-21	96.0	2E3QT@1|root,31FNG@2|Bacteria,2HGTF@201174|Actinobacteria,4CNV3@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3085147_2	1463856.JOHY01000035_gene1858	1.064e-59	234.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2GP5E@201174|Actinobacteria	201174|Actinobacteria	M	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SLT,SLT_2
SRR25158535_k127_3085147_1	1136417.AZWE01000095_gene4219	6.335e-70	262.0	COG3505@1|root,COG3505@2|Bacteria,2GNQ7@201174|Actinobacteria,4DFPJ@85008|Micromonosporales	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
SRR25158535_k127_3085147_5	414996.IL38_24325	4.663e-12	78.0	COG0210@1|root,COG0210@2|Bacteria,2IEWU@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3085147_0	653045.Strvi_6126	1.539e-78	272.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158535_k127_3088099_1	928724.SacglDRAFT_00832	2.844e-26	110.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4E2R0@85010|Pseudonocardiales	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SRR25158535_k127_3088099_2	395961.Cyan7425_1386	6.395e-12	70.0	COG3540@1|root,COG3540@2|Bacteria,1G0C9@1117|Cyanobacteria,3KG8D@43988|Cyanothece	1117|Cyanobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
SRR25158535_k127_3088099_0	994479.GL877878_gene44	2.139e-82	287.0	COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SRR25158535_k127_3090146_1	357808.RoseRS_2385	5.813e-123	401.0	COG0451@1|root,COG0451@2|Bacteria,2GAMV@200795|Chloroflexi,376SP@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158535_k127_3090146_2	1173028.ANKO01000018_gene1166	3.422e-75	256.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,1HAPT@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SRR25158535_k127_3090146_0	1157638.KB892157_gene1448	1.483e-209	665.0	COG4310@1|root,COG4310@2|Bacteria,2GK72@201174|Actinobacteria	201174|Actinobacteria	S	winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47,Peptidase_M28
SRR25158535_k127_3090146_7	351607.Acel_0404	1.566e-36	145.0	COG2246@1|root,COG2246@2|Bacteria,2IFFV@201174|Actinobacteria,4ET34@85013|Frankiales	201174|Actinobacteria	S	PFAM GtrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SRR25158535_k127_3090146_5	1313172.YM304_20400	9.259e-52	202.0	COG3463@1|root,COG3463@2|Bacteria	2|Bacteria	T	Predicted membrane protein (DUF2079)	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2079,HisKA_3
SRR25158535_k127_3090146_3	1122138.AQUZ01000001_gene1582	8.534e-70	239.0	COG1522@1|root,COG1522@2|Bacteria,2IG2K@201174|Actinobacteria,4DRJX@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix ASNC type	lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158535_k127_3090146_4	1123023.JIAI01000001_gene6962	5.252e-64	229.0	2F5XB@1|root,33YG1@2|Bacteria,2H6WG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3090146_6	562970.Btus_2812	1.35e-37	143.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,2797I@186823|Alicyclobacillaceae	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SRR25158535_k127_3091489_2	405948.SACE_6346	2.278e-31	127.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4E4UT@85010|Pseudonocardiales	201174|Actinobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SRR25158535_k127_3091489_0	471852.Tcur_1701	0.0	1048.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158535_k127_3091489_1	526226.Gbro_0449	4.051e-42	163.0	COG0454@1|root,COG0456@2|Bacteria,2HXQB@201174|Actinobacteria,4GGM9@85026|Gordoniaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
SRR25158535_k127_3091489_3	408672.NBCG_02605	2.87e-17	81.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DNK6@85009|Propionibacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
SRR25158535_k127_3092270_4	219305.MCAG_04144	5.183e-05	54.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria,4DB6R@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158535_k127_3092270_0	83332.Rv2811	1.63e-34	143.0	COG3677@1|root,COG3677@2|Bacteria,2IGIB@201174|Actinobacteria,239RI@1762|Mycobacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3092270_3	356851.JOAN01000007_gene4188	3.787e-10	72.0	COG1476@1|root,COG1476@2|Bacteria,2HM6E@201174|Actinobacteria,4DI7M@85008|Micromonosporales	201174|Actinobacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158535_k127_3092270_1	526225.Gobs_1457	1.354e-24	108.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158535_k127_3092270_2	1463856.JOHY01000054_gene7476	5.262e-14	82.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_3095966_0	485913.Krac_2149	7.573e-163	529.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2G872@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SRR25158535_k127_3097199_0	1449347.JQLN01000005_gene4858	4.226e-103	366.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,2M20W@2063|Kitasatospora	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158535_k127_3097199_4	1957.JODX01000001_gene5487	5.618e-14	78.0	COG5516@1|root,COG5516@2|Bacteria,2GP70@201174|Actinobacteria	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158535_k127_3097199_1	485913.Krac_11676	8.863e-80	276.0	COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Ornithine cyclodeaminase mu-crystallin	arcB	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
SRR25158535_k127_3097199_3	326424.FRAAL6206	1.372e-44	187.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4EV3P@85013|Frankiales	201174|Actinobacteria	S	TIGRFAM channel protein, hemolysin III family	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
SRR25158535_k127_3097199_2	1304865.JAGF01000001_gene715	2.363e-46	173.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_3100249_1	485913.Krac_6021	9.094e-55	207.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_3100249_0	1122138.AQUZ01000015_gene6875	3.822e-116	381.0	COG0596@1|root,COG0596@2|Bacteria,2GJDM@201174|Actinobacteria,4DQMZ@85009|Propionibacteriales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158535_k127_3100249_2	926554.KI912671_gene151	2.76e-33	134.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SRR25158535_k127_3100249_3	479431.Namu_4605	1.251e-07	53.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4ETZM@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_3104802_2	208444.JNYY01000001_gene4733	5.314e-55	197.0	COG3375@1|root,COG3375@2|Bacteria,2I8MV@201174|Actinobacteria,4DZFG@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3104802_0	1068978.AMETH_3897	2.751e-168	544.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4E02U@85010|Pseudonocardiales	201174|Actinobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113,5.5.1.1	ko:K01856,ko:K02549	ko00130,ko00361,ko00362,ko00364,ko00623,ko01100,ko01110,ko01120,ko01220,map00130,map00361,map00362,map00364,map00623,map01100,map01110,map01120,map01220	M00116,M00568	R04031,R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01053,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158535_k127_3104802_1	219305.MCAG_04852	1.456e-74	266.0	COG0265@1|root,COG0265@2|Bacteria,2GMIN@201174|Actinobacteria,4DAP9@85008|Micromonosporales	201174|Actinobacteria	O	Alpha-lytic protease prodomain	-	-	-	ko:K18547	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Pro_Al_protease,Trypsin
SRR25158535_k127_3106126_2	1968.JOEV01000087_gene2424	4.181e-21	98.0	COG1715@1|root,COG1715@2|Bacteria,2GP9K@201174|Actinobacteria	201174|Actinobacteria	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
SRR25158535_k127_3106126_1	1133850.SHJG_1549	6.344e-106	350.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SRR25158535_k127_3106126_0	345341.KUTG_08460	3.934e-112	368.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E23Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR25158535_k127_3109769_1	525909.Afer_1810	2.693e-29	119.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CP0K@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SRR25158535_k127_3109769_0	1463858.JOHR01000018_gene4378	1.323e-157	521.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
SRR25158535_k127_3123757_2	1380390.JIAT01000011_gene2299	8.546e-60	211.0	COG3025@1|root,COG3025@2|Bacteria,2IN8R@201174|Actinobacteria,4CSIW@84995|Rubrobacteria	84995|Rubrobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3123757_0	1380393.JHVP01000005_gene3676	4.446e-183	598.0	COG2909@1|root,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,4ETWF@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158535_k127_3123757_4	656024.FsymDg_1582	2.897e-11	70.0	COG0599@1|root,COG0599@2|Bacteria,2IS6K@201174|Actinobacteria,4EWB3@85013|Frankiales	201174|Actinobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SRR25158535_k127_3123757_1	1214242.B446_34775	1.284e-82	282.0	COG4291@1|root,COG4291@2|Bacteria,2GIW8@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SRR25158535_k127_3123757_3	1504319.GM45_2440	9.974e-23	104.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,3UWYX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158535_k127_3124398_2	345341.KUTG_00101	2.755e-14	76.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DX46@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_3124398_0	326424.FRAAL2497	2.931e-50	195.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
SRR25158535_k127_3124398_1	1288484.APCS01000073_gene283	5.735e-16	87.0	2CH9R@1|root,33MNW@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
SRR25158535_k127_313444_4	105425.BBPL01000024_gene319	5.165e-61	218.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,2NFS0@228398|Streptacidiphilus	201174|Actinobacteria	E	2Fe-2S iron-sulfur cluster binding domain	soxA	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
SRR25158535_k127_313444_6	479432.Sros_3857	6.06e-33	150.0	COG4311@1|root,COG4311@2|Bacteria,2IQIZ@201174|Actinobacteria,4EPU2@85012|Streptosporangiales	201174|Actinobacteria	E	Sarcosine oxidase, delta subunit family	soxD	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
SRR25158535_k127_313444_1	1120949.KB903322_gene2814	6.37e-195	614.0	COG0665@1|root,COG0665@2|Bacteria,2I8QS@201174|Actinobacteria	201174|Actinobacteria	E	Sarcosine oxidase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158535_k127_313444_3	1449976.KALB_3165	1.519e-67	239.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4E0VJ@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158535_k127_313444_0	68223.JNZY01000010_gene1845	3.307e-298	924.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
SRR25158535_k127_313444_5	309801.trd_1320	2.287e-49	188.0	arCOG06048@1|root,31EJQ@2|Bacteria,2G6TM@200795|Chloroflexi,27Z2Z@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_313444_2	1128421.JAGA01000003_gene3665	2.536e-100	337.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096,ko:K07496	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
SRR25158535_k127_313444_7	1128421.JAGA01000003_gene3664	1.938e-09	59.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
SRR25158535_k127_3145759_2	1077972.ARGLB_058_00140	9.242e-38	143.0	COG2267@1|root,COG2267@2|Bacteria,2GNRY@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SRR25158535_k127_3145759_3	1043493.BBLU01000006_gene2132	2.507e-21	98.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SRR25158535_k127_3145759_0	1394178.AWOO02000059_gene591	3.701e-85	291.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria,4EFMN@85012|Streptosporangiales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
SRR25158535_k127_3145759_1	1120949.KB903317_gene1732	1.532e-78	265.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DA13@85008|Micromonosporales	2|Bacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158535_k127_3178817_4	1056816.JAFQ01000004_gene3423	1.862e-30	136.0	COG5340@1|root,COG5340@2|Bacteria,2ISM9@201174|Actinobacteria,4G12Y@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
SRR25158535_k127_3178817_3	448385.sce7695	4.021e-40	159.0	COG1409@1|root,COG1409@2|Bacteria,1P3V8@1224|Proteobacteria,42UTI@68525|delta/epsilon subdivisions,2WYAV@28221|Deltaproteobacteria,2YWSN@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158535_k127_3178817_1	106370.Francci3_3305	2.216e-64	248.0	COG3505@1|root,COG3505@2|Bacteria,2ISKK@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
SRR25158535_k127_3178817_0	953739.SVEN_5628	1.492e-72	276.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3178817_2	1449347.JQLN01000005_gene5052	1.927e-50	198.0	28IJ8@1|root,2Z8K6@2|Bacteria,2GIV3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3181697_0	356851.JOAN01000016_gene6171	9.406e-131	445.0	COG2244@1|root,COG2244@2|Bacteria,2I4II@201174|Actinobacteria,4D8SP@85008|Micromonosporales	201174|Actinobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_C
SRR25158535_k127_3181697_1	356851.JOAN01000016_gene6173	3.064e-119	399.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
SRR25158535_k127_3181697_3	1385519.N801_18435	4.161e-57	216.0	COG2385@1|root,COG2385@2|Bacteria,2I3WB@201174|Actinobacteria,4FI8C@85021|Intrasporangiaceae	201174|Actinobacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SRR25158535_k127_3181697_2	261292.Nit79A3_1195	3.573e-58	214.0	29TUY@1|root,2ZFGG@2|Bacteria,1QY07@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158535_k127_3181697_5	1122622.ATWJ01000013_gene10	2.534e-45	183.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FFZV@85021|Intrasporangiaceae	201174|Actinobacteria	DM	biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
SRR25158535_k127_3182020_0	234267.Acid_3077	8.654e-263	825.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria	57723|Acidobacteria	Q	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158535_k127_3183565_0	2074.JNYD01000003_gene3740	2.18e-92	314.0	COG3547@1|root,COG3547@2|Bacteria,2HJ5P@201174|Actinobacteria,4E8DQ@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_3183565_1	2074.JNYD01000003_gene3740	3.966e-37	144.0	COG3547@1|root,COG3547@2|Bacteria,2HJ5P@201174|Actinobacteria,4E8DQ@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_3183565_3	68219.JNXI01000033_gene479	2.496e-05	49.0	2ER9N@1|root,33IV9@2|Bacteria,2GSJ1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3183565_2	1408418.JNJH01000041_gene717	4.641e-17	85.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,2JR2D@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
SRR25158535_k127_3185142_0	1121382.JQKG01000018_gene1119	1.205e-56	200.0	COG0304@1|root,COG0304@2|Bacteria,1WI34@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158535_k127_3185142_1	1449068.JMLQ01000005_gene3532	1.018e-41	164.0	2DF72@1|root,32U4U@2|Bacteria,2GIV4@201174|Actinobacteria,4G374@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3185142_2	1009370.ALO_10364	1.602e-35	151.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4H40H@909932|Negativicutes	909932|Negativicutes	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
SRR25158535_k127_3185142_3	479432.Sros_1513	4.263e-32	134.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2GNSN@201174|Actinobacteria,4EH2B@85012|Streptosporangiales	201174|Actinobacteria	P	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA,VWA_2
SRR25158535_k127_3186501_1	357808.RoseRS_2255	4.211e-102	343.0	28J69@1|root,2Z921@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3186501_0	357808.RoseRS_2256	8.818e-199	639.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	ko:K06915,ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,PLDc_2
SRR25158535_k127_3186501_2	342113.DM82_3253	9.481e-31	134.0	COG0210@1|root,COG0210@2|Bacteria,1MWW6@1224|Proteobacteria,2VM7D@28216|Betaproteobacteria,1K67M@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,NERD,UvrD-helicase,UvrD_C,UvrD_C_2
SRR25158535_k127_3187559_4	543632.JOJL01000070_gene3172	3.647e-52	185.0	COG4803@1|root,COG4803@2|Bacteria,2IHYU@201174|Actinobacteria,4DEJI@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
SRR25158535_k127_3187559_2	1380347.JNII01000005_gene3117	5.72e-87	301.0	COG4608@1|root,COG4608@2|Bacteria,2GMCD@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_3187559_0	1380390.JIAT01000010_gene3454	3.241e-109	376.0	COG0444@1|root,COG0444@2|Bacteria,2GN9K@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
SRR25158535_k127_3187559_3	1123320.KB889673_gene3626	1.91e-79	280.0	COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SRR25158535_k127_3187559_1	1380390.JIAT01000010_gene3451	1.735e-98	331.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CT8Q@84995|Rubrobacteria	84995|Rubrobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
SRR25158535_k127_3187559_5	1123320.KB889673_gene3624	1.765e-23	105.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_3189592_2	1463820.JOGW01000005_gene3412	9.989e-07	58.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_3189592_0	1120949.KB903350_gene8465	2.552e-69	244.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4DC3H@85008|Micromonosporales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IA	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158535_k127_3189592_1	40571.JOEA01000002_gene4989	2.364e-40	170.0	COG2244@1|root,COG2244@2|Bacteria,2GJV2@201174|Actinobacteria,4E1E5@85010|Pseudonocardiales	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
SRR25158535_k127_3191915_0	1122138.AQUZ01000001_gene1826	2.3e-93	315.0	COG1277@1|root,COG1277@2|Bacteria,2H46W@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
SRR25158535_k127_3191915_3	1122138.AQUZ01000001_gene1827	2.638e-37	149.0	COG1572@1|root,COG1572@2|Bacteria,2H888@201174|Actinobacteria	201174|Actinobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3191915_1	1254432.SCE1572_13050	3.343e-84	306.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,43BBS@68525|delta/epsilon subdivisions,2X6QY@28221|Deltaproteobacteria,2YU79@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158535_k127_3191915_2	981369.JQMJ01000004_gene4146	1.867e-63	224.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,2NGG6@228398|Streptacidiphilus	201174|Actinobacteria	EK	Aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158535_k127_3192865_1	1089553.Tph_c01350	1.866e-50	184.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,42FY1@68295|Thermoanaerobacterales	186801|Clostridia	L	Best Blastp hit gi 4323609 gb AAD16446.1 (AF101410) transposase Mycoplasma mycoides subsp. mycoides SC gi 4323611 gb AAD16447.1 (AF101411) transposase Mycoplasma mycoides subsp. mycoides SC gi 4323613 gb AAD16448.1 (AF101412) transposase Mycoplasma mycoides subsp. mycoides SC , score	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_3192865_0	345341.KUTG_04850	1.857e-65	243.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
SRR25158535_k127_3195593_0	1313172.YM304_04010	1.107e-103	340.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CN9T@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome b/b6/petB	-	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158535_k127_3195593_3	1229780.BN381_450012	4.797e-24	105.0	COG1143@1|root,COG1143@2|Bacteria,2H4NQ@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
SRR25158535_k127_3195593_2	68223.JNZY01000039_gene4515	3.732e-27	120.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158535_k127_3195593_1	1288083.AUKR01000012_gene536	1.142e-64	231.0	COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
SRR25158535_k127_3195593_4	1120949.KB903318_gene2027	3.174e-13	72.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4DAJ8@85008|Micromonosporales	201174|Actinobacteria	O	ResB protein required for cytochrome c biosynthesis	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
SRR25158535_k127_3196009_2	1121468.AUBR01000025_gene2973	7.032e-43	171.0	COG1215@1|root,COG1215@2|Bacteria,1UK60@1239|Firmicutes,24IGY@186801|Clostridia,42J7I@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SRR25158535_k127_3196009_3	1313172.YM304_20400	1.43e-41	175.0	COG3463@1|root,COG3463@2|Bacteria	2|Bacteria	T	Predicted membrane protein (DUF2079)	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2079,HisKA_3
SRR25158535_k127_3196009_1	1229780.BN381_10199	9.294e-85	310.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3196009_0	446462.Amir_0945	2.351e-96	321.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4DYEA@85010|Pseudonocardiales	201174|Actinobacteria	D	cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158535_k127_3196009_4	1184607.AUCHE_08_06370	6.07e-11	66.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4F6CT@85018|Dermatophilaceae	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158535_k127_3198536_1	321332.CYB_2038	5.834e-17	83.0	COG0120@1|root,COG0120@2|Bacteria,1G2DW@1117|Cyanobacteria,1GYUV@1129|Synechococcus	1117|Cyanobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.rpiA	Rib_5-P_isom_A
SRR25158535_k127_3198536_0	867903.ThesuDRAFT_00304	2.523e-138	452.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SRR25158535_k127_3200766_7	497964.CfE428DRAFT_2423	2.91e-53	198.0	COG3253@1|root,COG3253@2|Bacteria,46SQD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Chlorite dismutase	ywfI	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
SRR25158535_k127_3200766_6	469383.Cwoe_5826	3.182e-76	265.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CP8R@84995|Rubrobacteria	84995|Rubrobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
SRR25158535_k127_3200766_4	1123024.AUII01000013_gene447	2.641e-99	337.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4DZ12@85010|Pseudonocardiales	201174|Actinobacteria	S	Reductase C-terminal	fprD	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
SRR25158535_k127_3200766_3	298655.KI912266_gene5255	3.373e-103	349.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4EUA7@85013|Frankiales	201174|Actinobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_3200766_0	263358.VAB18032_11180	1.565e-164	542.0	COG4222@1|root,COG4222@2|Bacteria,2GJN8@201174|Actinobacteria,4DHG7@85008|Micromonosporales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158535_k127_3200766_10	570268.ANBB01000054_gene4617	0.0003573	48.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4EFN0@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SRR25158535_k127_3200766_8	1123024.AUII01000011_gene4412	1.515e-46	177.0	COG1309@1|root,COG1309@2|Bacteria,2GMCG@201174|Actinobacteria,4DXQ4@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_3200766_2	196162.Noca_3615	6.504e-109	365.0	COG0451@1|root,COG0451@2|Bacteria,2I1PI@201174|Actinobacteria,4DUKC@85009|Propionibacteriales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158535_k127_3200766_1	1229780.BN381_90073	6.116e-136	448.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_3200766_5	429009.Adeg_0661	4.435e-91	325.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
SRR25158535_k127_3200766_9	1120950.KB892707_gene4609	1.402e-21	105.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
SRR25158535_k127_3205910_16	675635.Psed_1636	2.238e-45	172.0	COG1396@1|root,COG3837@1|root,COG1396@2|Bacteria,COG3837@2|Bacteria,2INQP@201174|Actinobacteria	201174|Actinobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158535_k127_3205910_0	1123024.AUII01000053_gene167	2.167e-202	638.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EBET@85010|Pseudonocardiales	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
SRR25158535_k127_3205910_14	1123024.AUII01000034_gene2678	6.791e-62	222.0	COG2044@1|root,COG2044@2|Bacteria,2GJQS@201174|Actinobacteria,4DYQM@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SRR25158535_k127_3205910_5	1123024.AUII01000053_gene171	1.186e-153	504.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria,4E8S3@85010|Pseudonocardiales	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
SRR25158535_k127_3205910_18	1123024.AUII01000034_gene2687	3.934e-29	128.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158535_k127_3205910_2	675635.Psed_1623	7.951e-188	602.0	COG0165@1|root,COG0165@2|Bacteria,2I9W9@201174|Actinobacteria,4EA9J@85010|Pseudonocardiales	201174|Actinobacteria	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158535_k127_3205910_13	1123024.AUII01000034_gene2682	6.215e-69	258.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4EBSU@85010|Pseudonocardiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SRR25158535_k127_3205910_4	675635.Psed_1621	1.074e-156	523.0	COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4E8M1@85010|Pseudonocardiales	201174|Actinobacteria	F	Lyase	-	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SRR25158535_k127_3205910_12	1089544.KB912942_gene3164	1.411e-71	266.0	2DBFP@1|root,2Z8ZG@2|Bacteria,2IAVA@201174|Actinobacteria,4EAS9@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3205910_11	675635.Psed_6288	1.67e-87	297.0	COG1809@1|root,COG1809@2|Bacteria,2IESE@201174|Actinobacteria,4E51E@85010|Pseudonocardiales	201174|Actinobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
SRR25158535_k127_3205910_10	1123024.AUII01000028_gene2487	5.004e-103	344.0	COG2144@1|root,COG2144@2|Bacteria,2GM78@201174|Actinobacteria,4E1YB@85010|Pseudonocardiales	201174|Actinobacteria	S	AIR synthase related protein, C-terminal domain	thiL_1	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C,Acetyltransf_1,Acetyltransf_10
SRR25158535_k127_3205910_15	1123024.AUII01000053_gene175	1.33e-45	174.0	COG2153@1|root,COG2153@2|Bacteria	2|Bacteria	K	protein acetylation	yyaT	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
SRR25158535_k127_3205910_6	1123024.AUII01000009_gene2056	1.913e-146	481.0	COG2516@1|root,COG2516@2|Bacteria,2GN07@201174|Actinobacteria,4E1DF@85010|Pseudonocardiales	201174|Actinobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SRR25158535_k127_3205910_7	1123024.AUII01000005_gene2477	3.97e-146	467.0	COG2159@1|root,COG2159@2|Bacteria,2I9E4@201174|Actinobacteria,4E0Z3@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SRR25158535_k127_3205910_9	1123024.AUII01000053_gene172	2.309e-103	345.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4E9CR@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the carbamate kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158535_k127_3205910_3	1123024.AUII01000034_gene2675	4.876e-165	542.0	COG0074@1|root,COG0074@2|Bacteria,2GN20@201174|Actinobacteria,4E87Z@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
SRR25158535_k127_3205910_8	1123024.AUII01000034_gene2674	5.103e-130	432.0	COG0438@1|root,COG0438@2|Bacteria,2GKX4@201174|Actinobacteria,4E2H9@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_3205910_1	1155718.KB891914_gene1449	1.533e-198	626.0	COG0441@1|root,COG0441@2|Bacteria,2GNDW@201174|Actinobacteria	201174|Actinobacteria	J	threonine--tRNA ligase	thrS2	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
SRR25158535_k127_3205910_17	1366050.N234_10140	2.278e-35	148.0	COG1680@1|root,COG2815@1|root,COG1680@2|Bacteria,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,2W73Q@28216|Betaproteobacteria,1KDQJ@119060|Burkholderiaceae	28216|Betaproteobacteria	V	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
SRR25158535_k127_3205910_19	479433.Caci_4582	2.51e-21	106.0	2DEUK@1|root,2ZPBD@2|Bacteria,2GSEZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3210368_0	1464048.JNZS01000004_gene1329	4.093e-119	391.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4DBQM@85008|Micromonosporales	201174|Actinobacteria	S	amidohydrolase	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_3210368_3	469371.Tbis_2770	7.281e-51	186.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GXAS@201174|Actinobacteria,4EF8S@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158535_k127_3210368_4	1385521.N803_07380	3.377e-36	151.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4FGFA@85021|Intrasporangiaceae	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_3210368_1	477641.MODMU_4598	2.125e-88	299.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4ERCV@85013|Frankiales	201174|Actinobacteria	G	PFAM Inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SRR25158535_k127_3210368_6	1229780.BN381_210111	0.0006965	52.0	2C8AG@1|root,33SQR@2|Bacteria,2H3BF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3210368_5	1335760.ASTG01000019_gene2712	1.384e-11	78.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3210368_2	909613.UO65_3493	1.226e-58	211.0	COG4122@1|root,COG4122@2|Bacteria,2GPEV@201174|Actinobacteria,4E04Q@85010|Pseudonocardiales	201174|Actinobacteria	S	O-methyltransferase	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
SRR25158535_k127_3214427_4	1223544.GSI01S_25_00510	1.386e-66	231.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4GB5K@85026|Gordoniaceae	201174|Actinobacteria	O	C-terminal, D2-small domain, of ClpB protein	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_3214427_0	935863.AWZR01000005_gene2435	1.938e-146	483.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1X3GD@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SRR25158535_k127_3214427_1	561175.KB894097_gene337	1.242e-121	407.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4EGE8@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SRR25158535_k127_3214427_2	1116232.AHBF01000016_gene3590	1.069e-90	305.0	COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
SRR25158535_k127_3214427_3	1382304.JNIL01000001_gene811	2.001e-80	279.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,2784W@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SRR25158535_k127_3214427_7	1121926.AXWO01000023_gene286	5.13e-32	145.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria,4EYJX@85014|Glycomycetales	201174|Actinobacteria	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
SRR25158535_k127_3214427_8	298654.FraEuI1c_3352	1.201e-26	119.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
SRR25158535_k127_3214427_5	1246474.ANBE01000031_gene3338	4.916e-38	151.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4EJ6G@85012|Streptosporangiales	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
SRR25158535_k127_3214427_6	28042.GU90_15515	1.569e-32	130.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,4E4Z9@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SRR25158535_k127_3217901_2	358823.DF19_17710	1.556e-64	226.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
SRR25158535_k127_3217901_0	1068978.AMETH_0700	1.242e-147	481.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4DXC8@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	GO:0008150,GO:0040007	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SRR25158535_k127_3217901_5	351607.Acel_0342	5.651e-45	166.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4ESQW@85013|Frankiales	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SRR25158535_k127_3217901_3	351607.Acel_0341	4.573e-62	222.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4ESPF@85013|Frankiales	201174|Actinobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SRR25158535_k127_3217901_6	221288.JH992901_gene5371	1.035e-35	144.0	COG0110@1|root,COG0110@2|Bacteria,1GA9N@1117|Cyanobacteria,1JIJD@1189|Stigonemataceae	1117|Cyanobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SRR25158535_k127_3217901_7	164328.Phyra96233	0.0003891	51.0	COG3914@1|root,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	-	-	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,Methyltransf_11,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SRR25158535_k127_3217901_1	65497.JODV01000007_gene443	1.533e-65	232.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4DZVD@85010|Pseudonocardiales	201174|Actinobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SRR25158535_k127_3217901_4	351607.Acel_0335	3.598e-49	186.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4ESN1@85013|Frankiales	201174|Actinobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SRR25158535_k127_3219775_1	1242864.D187_003477	2.956e-75	267.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein 2	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
SRR25158535_k127_3219775_0	326424.FRAAL4607	1.261e-270	843.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4ERJA@85013|Frankiales	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SRR25158535_k127_3231197_1	1122182.KB903833_gene5652	5.777e-83	290.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4D9U9@85008|Micromonosporales	201174|Actinobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SRR25158535_k127_3231197_0	555088.DealDRAFT_1051	1.5e-84	286.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,42JMV@68298|Syntrophomonadaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158535_k127_3231197_2	1169152.AXVD01000012_gene1756	5.565e-08	55.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4FUIR@85025|Nocardiaceae	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SRR25158535_k127_3236714_4	28444.JODQ01000004_gene6378	3.071e-10	61.0	COG4585@1|root,COG4585@2|Bacteria,2GQQ8@201174|Actinobacteria,4ENSE@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_3236714_1	1463920.JOGB01000002_gene3215	1.063e-83	285.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_3236714_5	469383.Cwoe_0291	0.0002644	52.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158535_k127_3236714_0	1229780.BN381_130377	6.275e-90	317.0	2CC51@1|root,2Z7IU@2|Bacteria,2GM14@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
SRR25158535_k127_3236714_2	1229780.BN381_130378	4.188e-65	240.0	28HUD@1|root,2Z9YN@2|Bacteria,2I83C@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2398
SRR25158535_k127_3236714_3	1229780.BN381_130379	6.599e-59	232.0	COG1196@1|root,COG1196@2|Bacteria,2GK6F@201174|Actinobacteria	201174|Actinobacteria	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
SRR25158535_k127_3282411_3	457429.ABJI02000009_gene2741	7.939e-34	132.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158535_k127_3282411_0	1445613.JALM01000013_gene1898	2.58e-206	658.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4E05J@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase, CocE NonD family	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158535_k127_3282411_1	526225.Gobs_2776	3.841e-195	621.0	COG2755@1|root,COG2755@2|Bacteria,2ICJT@201174|Actinobacteria,4EV4J@85013|Frankiales	201174|Actinobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,RicinB_lectin_2
SRR25158535_k127_3282411_2	983917.RGE_11590	1.38e-158	511.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2VTNQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
SRR25158535_k127_3283185_1	1120950.KB892792_gene2416	7.064e-119	406.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria,4DWM5@85009|Propionibacteriales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158535_k127_3283185_4	67267.JNXT01000096_gene5252	4.338e-40	168.0	COG1846@1|root,COG1846@2|Bacteria,2IIEW@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158535_k127_3283185_9	935839.JAGJ01000001_gene1137	4.25e-11	74.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4F4U6@85017|Promicromonosporaceae	201174|Actinobacteria	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_3283185_7	1121272.KB903290_gene4484	4.509e-24	106.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4DEWR@85008|Micromonosporales	201174|Actinobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158535_k127_3283185_0	1123024.AUII01000006_gene4644	7.624e-135	443.0	COG0654@1|root,COG0654@2|Bacteria,2GNA8@201174|Actinobacteria,4E77N@85010|Pseudonocardiales	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.10	ko:K19189	ko00760,ko01120,map00760,map01120	-	R04130	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8
SRR25158535_k127_3283185_2	113395.AXAI01000002_gene5169	1.722e-57	205.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
SRR25158535_k127_3283185_5	465541.ATCJ01000005_gene7105	1.875e-28	118.0	COG1917@1|root,COG1917@2|Bacteria,2IGQV@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3283185_3	298655.KI912267_gene7268	6.836e-42	169.0	COG0683@1|root,COG0683@2|Bacteria,2H1ZK@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158535_k127_3283185_6	1206737.BAGF01000006_gene470	2.609e-24	106.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4FTXC@85025|Nocardiaceae	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_3283185_8	1068978.AMETH_6551	3.893e-22	100.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJD@85010|Pseudonocardiales	201174|Actinobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990,ko:K18232	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC_tran,DUF4162
SRR25158535_k127_3284154_3	562970.Btus_1862	7.12e-28	121.0	COG0768@1|root,COG2815@1|root,COG0768@2|Bacteria,COG2815@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,277Y0@186823|Alicyclobacillaceae	91061|Bacilli	M	stage V sporulation protein D	spoVD	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
SRR25158535_k127_3284154_5	66377.JOBH01000007_gene2018	0.0001533	54.0	COG2919@1|root,COG2919@2|Bacteria,2I3SE@201174|Actinobacteria	201174|Actinobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
SRR25158535_k127_3284154_0	429009.Adeg_1572	1.04e-91	321.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,42EWY@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SRR25158535_k127_3284154_2	1304880.JAGB01000002_gene1526	4.344e-42	159.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SRR25158535_k127_3284154_1	471852.Tcur_0545	9.855e-68	252.0	COG1408@1|root,COG1408@2|Bacteria,2GM8M@201174|Actinobacteria,4ER1A@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SRR25158535_k127_3284154_4	1169161.KB897715_gene5492	5.197e-08	55.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria	201174|Actinobacteria	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SRR25158535_k127_3284327_0	543632.JOJL01000012_gene6582	2.995e-117	383.0	COG3267@1|root,COG3267@2|Bacteria,2IA4V@201174|Actinobacteria	201174|Actinobacteria	U	Type II secretory pathway component ExeA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
SRR25158535_k127_3284327_4	1299327.I546_2252	4.619e-09	68.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria,236H8@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase, catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,Mu-transpos_C,rve
SRR25158535_k127_3284327_2	436229.JOEH01000054_gene6400	2.024e-50	205.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria,2NKFK@228398|Streptacidiphilus	201174|Actinobacteria	L	Mu transposase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,Mu-transpos_C,rve
SRR25158535_k127_3284327_1	543632.JOJL01000132_gene3147	2.719e-67	239.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria	2|Bacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,Mu-transpos_C,rve
SRR25158535_k127_3284327_3	1032480.MLP_18830	2.419e-45	172.0	COG3677@1|root,COG3677@2|Bacteria,2IGIB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3290607_2	566461.SSFG_07338	2.997e-05	47.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
SRR25158535_k127_3290607_0	1299327.I546_0741	1.974e-239	752.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2
SRR25158535_k127_3290607_1	1121935.AQXX01000135_gene3743	2.468e-08	57.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,1S5K2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase type 11	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
SRR25158535_k127_3302715_2	215803.DB30_7014	2.233e-10	61.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2WND0@28221|Deltaproteobacteria,2YUS9@29|Myxococcales	28221|Deltaproteobacteria	L	similarity to GB AAB68949.1	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas1,GIIM,RVT_1
SRR25158535_k127_3302715_5	1230460.C495_16335	0.0004861	48.0	arCOG06178@1|root,arCOG06178@2157|Archaea,2Y0DH@28890|Euryarchaeota,23XPC@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3302715_0	106370.Francci3_2088	2.281e-234	750.0	COG1961@1|root,COG1961@2|Bacteria,2INJA@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_3302715_4	1123320.KB889732_gene6220	2.74e-07	55.0	COG1961@1|root,COG1961@2|Bacteria,2INJA@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_3302715_1	345341.KUTG_10172	3.824e-143	461.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E23Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR25158535_k127_3305797_8	1172180.KB911775_gene6297	0.0003691	51.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158535_k127_3305797_6	572544.Ilyop_0546	4.959e-22	110.0	COG2154@1|root,COG2154@2|Bacteria	2|Bacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SRR25158535_k127_3305797_0	1944.JOAZ01000023_gene2555	8.737e-97	334.0	COG1131@1|root,COG1131@2|Bacteria,2IE14@201174|Actinobacteria	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158535_k127_3305797_1	1463936.JOJI01000001_gene1858	8.502e-85	304.0	COG0842@1|root,COG0842@2|Bacteria,2I9MM@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
SRR25158535_k127_3305797_3	351607.Acel_1636	2.709e-43	167.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4ESNJ@85013|Frankiales	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
SRR25158535_k127_3305797_5	66377.JOBH01000003_gene5241	1.032e-27	130.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria	201174|Actinobacteria	NU	MobA-related protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
SRR25158535_k127_3305797_2	298653.Franean1_6196	2.209e-64	235.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria,4ERTW@85013|Frankiales	201174|Actinobacteria	O	XdhC Rossmann domain	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
SRR25158535_k127_3305797_4	357808.RoseRS_0502	3.705e-33	131.0	COG1975@1|root,COG1975@2|Bacteria,2G6Z8@200795|Chloroflexi,377G6@32061|Chloroflexia	32061|Chloroflexia	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
SRR25158535_k127_3307473_0	469383.Cwoe_5866	8.286e-114	380.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRR25158535_k127_3307473_1	398767.Glov_2315	1.063e-73	260.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
SRR25158535_k127_3308419_8	861299.J421_0680	1.007e-59	228.0	COG2072@1|root,COG2072@2|Bacteria,1ZV84@142182|Gemmatimonadetes	2|Bacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158535_k127_3308419_1	1394178.AWOO02000012_gene3773	1.37e-201	657.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SRR25158535_k127_3308419_2	58123.JOFJ01000006_gene203	3.421e-192	633.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4EG9Z@85012|Streptosporangiales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158535_k127_3308419_13	649831.L083_1234	1.721e-35	149.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,P22_AR_N,PriCT_1,Prim-Pol
SRR25158535_k127_3308419_0	68170.KL590506_gene9752	3.45e-206	692.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2GKKQ@201174|Actinobacteria,4DYP0@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	embR	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006355,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019538,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0080090,GO:0090407,GO:0097159,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,FHA,Trans_reg_C,Yop-YscD_cpl
SRR25158535_k127_3308419_16	439497.RR11_2792	2.007e-08	63.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2TUIS@28211|Alphaproteobacteria,4NB9G@97050|Ruegeria	28211|Alphaproteobacteria	K	Transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_3308419_15	1382356.JQMP01000003_gene1492	1.279e-25	119.0	arCOG08811@1|root,32UTS@2|Bacteria,2G8VM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3308419_12	67315.JOBD01000019_gene7554	1.025e-37	161.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
SRR25158535_k127_3308419_4	263358.VAB18032_27071	3.575e-108	390.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158535_k127_3308419_18	298653.Franean1_0745	5.235e-07	62.0	COG3147@1|root,COG3147@2|Bacteria,2I8WA@201174|Actinobacteria,4EW20@85013|Frankiales	201174|Actinobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3308419_14	269800.Tfu_2625	7.039e-30	136.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4EG7R@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SRR25158535_k127_3308419_5	710686.Mycsm_01630	1.232e-106	358.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,235VP@1762|Mycobacteriaceae	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
SRR25158535_k127_3308419_10	929712.KI912613_gene4904	4.727e-43	167.0	COG1335@1|root,COG1488@1|root,COG1335@2|Bacteria,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
SRR25158535_k127_3308419_3	1382356.JQMP01000003_gene1569	9.465e-111	368.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi,27XNT@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158535_k127_3308419_11	1157637.KB892124_gene829	1.704e-38	165.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,PAS,PAS_4,SpoIIE
SRR25158535_k127_3308419_19	543632.JOJL01000001_gene7591	7.639e-05	55.0	2DA90@1|root,32TUY@2|Bacteria,2GKD0@201174|Actinobacteria,4DAT9@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3308419_7	196162.Noca_2908	1.54e-62	220.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4DQW7@85009|Propionibacteriales	201174|Actinobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SRR25158535_k127_3308419_17	1996.JOFO01000048_gene2728	1.084e-07	64.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3308419_9	987059.RBXJA2T_00894	9.962e-51	187.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VXVS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_3308419_6	471852.Tcur_1053	2.521e-87	295.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4EG1M@85012|Streptosporangiales	201174|Actinobacteria	S	von Willebrand factor (vWF) type A domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	VWA_2
SRR25158535_k127_3311258_1	298654.FraEuI1c_0095	2.502e-40	159.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4ES3X@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352,Pkinase
SRR25158535_k127_3311258_0	561175.KB894107_gene5522	2.898e-44	176.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4EGJ4@85012|Streptosporangiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SRR25158535_k127_3315156_5	1463934.JOCF01000013_gene3688	9.621e-12	72.0	COG0747@1|root,COG0747@2|Bacteria,2GJXH@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SRR25158535_k127_3315156_2	471852.Tcur_2297	2.051e-92	313.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4EFUB@85012|Streptosporangiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SRR25158535_k127_3315156_7	1380393.JHVP01000005_gene3554	1.484e-05	57.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4ES1X@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158535_k127_3315156_6	1283283.ATXA01000003_gene1592	4.376e-06	52.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria	201174|Actinobacteria	O	organic hydroperoxide resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
SRR25158535_k127_3315156_4	1298863.AUEP01000013_gene4066	1.999e-18	96.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4DR35@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158535_k127_3315156_8	1120934.KB894403_gene319	0.0003961	46.0	COG3371@1|root,COG3371@2|Bacteria,2II34@201174|Actinobacteria,4E5HW@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
SRR25158535_k127_3315156_3	390989.JOEG01000003_gene4509	1.031e-49	180.0	COG3576@1|root,COG3576@2|Bacteria,2I3PF@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_3315156_0	1120950.KB892748_gene3265	4.288e-171	543.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DP0M@85009|Propionibacteriales	201174|Actinobacteria	L	ATP dependent DNA ligase C terminal region	ligC	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SRR25158535_k127_3315156_1	1120949.KB903317_gene1732	4.352e-152	497.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DA13@85008|Micromonosporales	2|Bacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158535_k127_3315513_0	1499967.BAYZ01000085_gene5181	8.68e-40	159.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
SRR25158535_k127_3319550_1	1125863.JAFN01000001_gene1869	1.069e-101	359.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SRR25158535_k127_3319550_0	1223523.H340_13132	3.018e-113	379.0	COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
SRR25158535_k127_3319550_2	1395516.PMO01_10170	8.27e-12	66.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RYEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	bphP	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY,Response_reg
SRR25158535_k127_3319965_1	511051.CSE_07230	3.885e-36	140.0	COG0740@1|root,COG0740@2|Bacteria	2|Bacteria	OU	serine-type endopeptidase activity	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158535_k127_3319965_0	1380390.JIAT01000009_gene1407	2.835e-40	158.0	COG0637@1|root,COG0637@2|Bacteria,2IQD3@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SRR25158535_k127_3319965_2	1206732.BAGD01000081_gene3290	9.635e-26	118.0	COG0477@1|root,COG0477@2|Bacteria,2I31V@201174|Actinobacteria,4G8KT@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_3323851_2	28444.JODQ01000010_gene3136	3.257e-78	272.0	COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4EHKZ@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SRR25158535_k127_3323851_3	526227.Mesil_0060	1.953e-31	133.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,1WI3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_3323851_1	1157637.KB892146_gene7135	2.568e-90	307.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
SRR25158535_k127_3323851_0	749414.SBI_02611	3.126e-153	494.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
SRR25158535_k127_3327302_6	1121035.AUCH01000002_gene1663	1.207e-14	74.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,2KUTU@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
SRR25158535_k127_3327302_5	1232410.KI421412_gene149	1.624e-19	93.0	COG1371@1|root,COG1371@2|Bacteria,1NCP6@1224|Proteobacteria,42VQE@68525|delta/epsilon subdivisions,2WS6C@28221|Deltaproteobacteria,43VMN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
SRR25158535_k127_3327302_0	263358.VAB18032_21020	1.669e-166	538.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4DBFQ@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the RtcB family	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415,ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	RtcB
SRR25158535_k127_3327302_1	1121926.AXWO01000013_gene2116	6.303e-80	273.0	COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Erythro_esteras,Pribosyltran
SRR25158535_k127_3327302_3	656024.FsymDg_2715	1.486e-63	232.0	COG1503@1|root,COG1503@2|Bacteria,2GNN3@201174|Actinobacteria,4EVI4@85013|Frankiales	201174|Actinobacteria	J	translation release factor activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
SRR25158535_k127_3327302_4	367299.JOEE01000001_gene2026	3.386e-57	206.0	COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4FG3C@85021|Intrasporangiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158535_k127_3327302_7	563192.HMPREF0179_00488	3.686e-11	74.0	COG1266@1|root,COG1266@2|Bacteria,1N67K@1224|Proteobacteria,42UUV@68525|delta/epsilon subdivisions,2WR6B@28221|Deltaproteobacteria,2MEXQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158535_k127_3327302_2	1120958.AULD01000010_gene2392	7.53e-74	257.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4FMRY@85023|Microbacteriaceae	201174|Actinobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
SRR25158535_k127_3330824_5	42256.RradSPS_3010	2.927e-52	208.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4CR64@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SRR25158535_k127_3330824_1	35754.JNYJ01000001_gene7304	8.954e-212	671.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4D9RA@85008|Micromonosporales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0055114	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
SRR25158535_k127_3330824_7	502025.Hoch_1840	1.532e-49	186.0	COG1309@1|root,COG1309@2|Bacteria,1RE7F@1224|Proteobacteria,43DYV@68525|delta/epsilon subdivisions,2WZ80@28221|Deltaproteobacteria,2Z1J0@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_3330824_0	1229780.BN381_20105	1.61e-250	786.0	COG2303@1|root,COG2303@2|Bacteria,2GJ3J@201174|Actinobacteria,3UX7I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	choA	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
SRR25158535_k127_3330824_6	263358.VAB18032_21245	4.064e-51	189.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4DDF0@85008|Micromonosporales	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_3330824_3	383372.Rcas_2064	5.757e-106	353.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158535_k127_3330824_8	471852.Tcur_0705	2.609e-30	124.0	COG0517@1|root,COG0517@2|Bacteria,2I26I@201174|Actinobacteria,4EQHS@85012|Streptosporangiales	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158535_k127_3330824_4	1123368.AUIS01000037_gene28	1.037e-82	295.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	pgmB	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576	2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6	ko:K01087,ko:K01194,ko:K01838,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R02778,R11310	RC00017,RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase,Trehalose_PPase
SRR25158535_k127_3330824_2	1088721.NSU_3017	1.874e-175	565.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,2U1CG@28211|Alphaproteobacteria,2K3VK@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	2.4.1.64,5.4.2.6	ko:K01838,ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SRR25158535_k127_333414_1	1348663.KCH_43300	2.597e-44	165.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,2M1WZ@2063|Kitasatospora	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
SRR25158535_k127_333414_0	58123.JOFJ01000017_gene4162	4.111e-64	231.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4EIYA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SRR25158535_k127_333414_2	1380393.JHVP01000003_gene892	2.713e-39	155.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria,4ERCU@85013|Frankiales	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SRR25158535_k127_3334182_9	1214101.BN159_0146	1.054e-40	153.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria	201174|Actinobacteria	L	resolvase	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
SRR25158535_k127_3334182_5	1120950.KB892770_gene1376	2.606e-105	350.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4DNBF@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SRR25158535_k127_3334182_4	710685.MycrhN_3037	1.818e-136	450.0	arCOG02771@1|root,2Z8A4@2|Bacteria,2GNG0@201174|Actinobacteria,23FGV@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3334182_12	408672.NBCG_02537	3.288e-16	88.0	COG1622@1|root,COG1622@2|Bacteria,2GS05@201174|Actinobacteria,4DSJB@85009|Propionibacteriales	201174|Actinobacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
SRR25158535_k127_3334182_13	1120948.KB903247_gene4424	5.769e-15	90.0	2F02G@1|root,33T66@2|Bacteria,2IGPI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3334182_2	266117.Rxyl_2271	4.68e-181	593.0	COG0028@1|root,COG0028@2|Bacteria,2GKGX@201174|Actinobacteria,4CPP0@84995|Rubrobacteria	84995|Rubrobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SRR25158535_k127_3334182_11	1394178.AWOO02000046_gene6469	5.063e-19	102.0	COG2203@1|root,COG2203@2|Bacteria,2HGVH@201174|Actinobacteria,4EJDR@85012|Streptosporangiales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
SRR25158535_k127_3334182_0	266117.Rxyl_2540	8.855e-229	733.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
SRR25158535_k127_3334182_3	485913.Krac_1407	1.651e-149	492.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Metallophos,PAP2
SRR25158535_k127_3334182_14	309800.C498_03934	1.354e-06	59.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XW2T@28890|Euryarchaeota,23U9Q@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_3334182_6	358823.DF19_32420	6.884e-87	309.0	COG0666@1|root,COG0666@2|Bacteria,2I9A2@201174|Actinobacteria	201174|Actinobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
SRR25158535_k127_3334182_7	710111.FraQA3DRAFT_1591	2.42e-59	225.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria,4ESV0@85013|Frankiales	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
SRR25158535_k127_3334182_8	477641.MODMU_5370	7.398e-47	194.0	COG0748@1|root,COG0748@2|Bacteria,2IFHD@201174|Actinobacteria,4EWF6@85013|Frankiales	201174|Actinobacteria	P	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_3334182_1	35754.JNYJ01000009_gene1953	4.87e-195	625.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2H3FC@201174|Actinobacteria	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158535_k127_3335075_1	1048339.KB913029_gene2869	9.227e-48	179.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4EVYI@85013|Frankiales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SRR25158535_k127_3335075_3	1128421.JAGA01000002_gene111	0.0001093	53.0	COG5401@1|root,COG5401@2|Bacteria	2|Bacteria	T	PFAM Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
SRR25158535_k127_3335075_2	292459.STH1400	8.248e-41	162.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SRR25158535_k127_3335075_0	867845.KI911784_gene466	2.386e-232	745.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158535_k127_3335162_2	47763.JNZA01000012_gene6438	0.0004132	43.0	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SRR25158535_k127_3335162_1	1429046.RR21198_4923	7.668e-95	327.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4G1Y6@85025|Nocardiaceae	201174|Actinobacteria	I	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,PAP2_3,WES_acyltransf
SRR25158535_k127_3335162_0	1122138.AQUZ01000025_gene2804	1.135e-101	345.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158535_k127_3335988_1	1211815.CBYP010000056_gene3330	9.848e-91	329.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_3335988_0	326424.FRAAL5853	3.726e-152	504.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4ES0M@85013|Frankiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158535_k127_3335988_2	767817.Desgi_2457	1.454e-75	258.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2613E@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158535_k127_3342852_14	446468.Ndas_4905	2.052e-07	55.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4EGP7@85012|Streptosporangiales	201174|Actinobacteria	GK	DeoR C terminal sensor domain	glpR	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
SRR25158535_k127_3342852_3	590998.Celf_0080	1.044e-60	238.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4F2RT@85016|Cellulomonadaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 3 N terminal domain	lpqI	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SRR25158535_k127_3342852_0	211114.JOEF01000044_gene6144	7.479e-195	625.0	COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4DZCG@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
SRR25158535_k127_3342852_8	67373.JOBF01000003_gene340	1.708e-32	134.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SRR25158535_k127_3342852_1	365528.KB891241_gene6214	3.767e-138	454.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4EUMC@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_3342852_9	1211815.CBYP010000075_gene2951	3.492e-31	133.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SRR25158535_k127_3342852_12	479435.Kfla_4827	1.63e-18	88.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4DRPI@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158535_k127_3342852_4	1123258.AQXZ01000019_gene2684	6.921e-58	206.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,4G0VQ@85025|Nocardiaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
SRR25158535_k127_3342852_5	345341.KUTG_06495	1.873e-55	206.0	COG0346@1|root,COG0346@2|Bacteria,2IKKR@201174|Actinobacteria,4E5JI@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_3342852_11	1121033.AUCF01000032_gene2611	1.589e-27	119.0	COG0824@1|root,COG0824@2|Bacteria,1MZB3@1224|Proteobacteria,2U7CU@28211|Alphaproteobacteria,2JTMB@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
SRR25158535_k127_3342852_2	1068978.AMETH_1262	9.348e-93	319.0	COG2133@1|root,COG2133@2|Bacteria,2ID9F@201174|Actinobacteria	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SRR25158535_k127_3342852_15	1163398.AJJP01000203_gene3620	0.00011	54.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,1S5YT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
SRR25158535_k127_3342852_7	1121946.AUAX01000019_gene7793	5.075e-35	139.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria,4DEVY@85008|Micromonosporales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158535_k127_3342852_13	1382356.JQMP01000004_gene207	2.492e-14	81.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
SRR25158535_k127_3342852_6	1194972.MVAC_01720	2.932e-53	199.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,235NM@1762|Mycobacteriaceae	201174|Actinobacteria	O	Peroxiredoxin	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
SRR25158535_k127_3342852_10	760117.JN27_00615	4.629e-28	117.0	COG0346@1|root,COG0346@2|Bacteria,1RGTU@1224|Proteobacteria,2VUE3@28216|Betaproteobacteria	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_334292_3	452652.KSE_52510	1.115e-43	168.0	COG1961@1|root,COG1961@2|Bacteria,2I8IZ@201174|Actinobacteria,2M5NA@2063|Kitasatospora	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_334292_1	1032480.MLP_22200	7.754e-135	439.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,4DPQ1@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
SRR25158535_k127_334292_5	526225.Gobs_3640	7.108e-34	136.0	2BIEE@1|root,32T9G@2|Bacteria,2I86Y@201174|Actinobacteria,4EXJ3@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_334292_0	1267535.KB906767_gene721	7.051e-138	464.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
SRR25158535_k127_334292_4	1380346.JNIH01000004_gene2268	3.238e-37	154.0	COG1006@1|root,COG1006@2|Bacteria,2II0N@201174|Actinobacteria	201174|Actinobacteria	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
SRR25158535_k127_334292_2	404380.Gbem_1675	1.787e-56	207.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,42S1S@68525|delta/epsilon subdivisions,2WNIJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Na H antiporter MnhB subunit-related protein	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
SRR25158535_k127_3348041_0	1380354.JIAN01000009_gene3732	6.944e-163	527.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_3362436_5	1123024.AUII01000033_gene1403	7.406e-26	111.0	COG4994@1|root,COG4994@2|Bacteria,2ISVE@201174|Actinobacteria,4E603@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SRR25158535_k127_3362436_1	1120950.KB892707_gene4764	4.248e-68	238.0	COG1309@1|root,COG1309@2|Bacteria,2IP3P@201174|Actinobacteria,4DSN9@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_3362436_2	2045.KR76_11635	4.929e-53	199.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria,4DPPY@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
SRR25158535_k127_3362436_0	1032480.MLP_09830	4.029e-81	275.0	COG0262@1|root,COG0262@2|Bacteria,2GJU5@201174|Actinobacteria,4DUJC@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_3362436_3	1121272.KB903249_gene1982	5.497e-47	178.0	COG0748@1|root,COG0748@2|Bacteria,2INF5@201174|Actinobacteria,4DFP3@85008|Micromonosporales	201174|Actinobacteria	P	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_3362436_4	1394178.AWOO02000048_gene6367	1.856e-26	112.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria,4EM4J@85012|Streptosporangiales	201174|Actinobacteria	EK	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
SRR25158535_k127_3366820_1	1040989.AWZU01000003_gene6668	3.782e-134	445.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,3JW29@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	MA20_06335	-	4.2.1.156,4.2.1.42,5.1.2.2	ko:K01781,ko:K20023	ko00053,ko00627,ko01120,map00053,map00627,map01120	-	R03791,R04161,R05608	RC00543,RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SRR25158535_k127_3366820_4	1122182.KB903814_gene3544	6.93e-10	71.0	COG0637@1|root,COG0637@2|Bacteria,2GMIQ@201174|Actinobacteria,4DDJN@85008|Micromonosporales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158535_k127_3366820_2	1463887.KL589998_gene6933	7.681e-62	234.0	COG0637@1|root,COG0637@2|Bacteria,2GMIQ@201174|Actinobacteria	201174|Actinobacteria	Q	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SRR25158535_k127_3366820_0	1120950.KB892801_gene1690	4.483e-197	629.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4DNX4@85009|Propionibacteriales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SRR25158535_k127_3366820_3	471852.Tcur_1771	1.294e-54	199.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4EFXN@85012|Streptosporangiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	1.1.1.193	ko:K00082	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R03458	RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
SRR25158535_k127_3370442_1	1042877.GQS_01680	0.000838	46.0	COG1208@1|root,arCOG00666@2157|Archaea,2XU8E@28890|Euryarchaeota,243C3@183968|Thermococci	183968|Thermococci	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SRR25158535_k127_3370442_0	1283283.ATXA01000004_gene4354	3.328e-26	123.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	sumf2	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158535_k127_3373103_0	675635.Psed_4839	0.0	1269.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4E00A@85010|Pseudonocardiales	201174|Actinobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SRR25158535_k127_3374643_1	1120950.KB892768_gene5196	1.678e-52	192.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4DPEP@85009|Propionibacteriales	201174|Actinobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SRR25158535_k127_3374643_5	1120949.KB903296_gene9443	1.407e-18	96.0	2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DE78@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3374643_2	1380390.JIAT01000011_gene2542	4.722e-48	179.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4CRQ5@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_3374643_3	314285.KT71_14044	1.195e-44	186.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RWTA@1236|Gammaproteobacteria,1J94U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SRR25158535_k127_3374643_0	471852.Tcur_4898	5.92e-180	608.0	COG1506@1|root,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4EHY6@85012|Streptosporangiales	201174|Actinobacteria	E	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S9
SRR25158535_k127_3374643_4	653045.Strvi_6447	9.155e-20	94.0	COG5659@1|root,COG5659@2|Bacteria,2H7Y3@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_3386424_8	479433.Caci_1195	2.247e-29	126.0	COG4709@1|root,COG4709@2|Bacteria,2IMJF@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3386424_1	1206741.BAFX01000108_gene1181	4.072e-139	474.0	COG2909@1|root,COG2909@2|Bacteria,2GM03@201174|Actinobacteria,4FU86@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,GerE
SRR25158535_k127_3386424_6	1380390.JIAT01000009_gene1158	2.425e-57	206.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SRR25158535_k127_3386424_0	469371.Tbis_3206	2.021e-184	590.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DXMM@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_3386424_7	1068980.ARVW01000001_gene863	1.866e-45	181.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria	201174|Actinobacteria	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SRR25158535_k127_3386424_4	1068980.ARVW01000001_gene862	1.594e-111	380.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria,4E2EI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA5	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158535_k127_3386424_2	67373.JOBF01000016_gene4823	1.122e-134	452.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_3386424_5	649831.L083_3500	4.177e-88	299.0	COG3629@1|root,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
SRR25158535_k127_3386424_3	485913.Krac_0608	1.181e-127	430.0	COG0477@1|root,COG0477@2|Bacteria,2G7N2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_3386424_9	1379698.RBG1_1C00001G1271	4.909e-20	100.0	COG1630@1|root,COG1630@2|Bacteria	2|Bacteria	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
SRR25158535_k127_33946_5	1385518.N798_01355	1.277e-19	97.0	COG2032@1|root,COG2032@2|Bacteria	2|Bacteria	P	superoxide dismutase activity	sodC	-	1.15.1.1	ko:K02674,ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	-	-	-	Sod_Cu
SRR25158535_k127_33946_0	1122138.AQUZ01000036_gene5466	7.535e-61	222.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_33946_2	1385518.N798_01345	2.772e-54	206.0	2F7D1@1|root,33ZU2@2|Bacteria,2ITDT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_33946_4	1463854.JOHT01000002_gene2210	5.675e-22	105.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_33946_1	1089544.KB912942_gene1701	1.091e-58	215.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4E3CK@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_33946_3	1463820.JOGW01000003_gene7245	8.366e-29	118.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_3396479_0	369723.Strop_3041	4.399e-103	356.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria,4DBR2@85008|Micromonosporales	201174|Actinobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
SRR25158535_k127_3396479_4	1121468.AUBR01000004_gene176	2.639e-05	50.0	COG0265@1|root,COG0265@2|Bacteria,1TRQS@1239|Firmicutes,24E3C@186801|Clostridia,42FVK@68295|Thermoanaerobacterales	186801|Clostridia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SRR25158535_k127_3396479_1	323261.Noc_1844	9.291e-89	308.0	COG0265@1|root,COG0265@2|Bacteria,1R6VW@1224|Proteobacteria,1SNEA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3396479_3	351607.Acel_1410	7.588e-48	185.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria,4ET5G@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158535_k127_3396479_2	1380394.JADL01000010_gene4324	3.177e-81	273.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,2TR0V@28211|Alphaproteobacteria,2JRHD@204441|Rhodospirillales	204441|Rhodospirillales	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
SRR25158535_k127_3406297_3	1122138.AQUZ01000003_gene565	7.558e-77	273.0	COG0477@1|root,COG2814@2|Bacteria,2HDWW@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_3406297_10	1122138.AQUZ01000003_gene566	4.556e-36	145.0	COG5516@1|root,COG5516@2|Bacteria,2GJZN@201174|Actinobacteria,4DWU3@85009|Propionibacteriales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
SRR25158535_k127_3406297_8	656024.FsymDg_0320	4.288e-54	201.0	COG1928@1|root,COG1928@2|Bacteria,2GQQV@201174|Actinobacteria	201174|Actinobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3406297_2	1382306.JNIM01000001_gene1934	1.893e-90	308.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158535_k127_3406297_13	369723.Strop_3617	5.265e-14	85.0	2E3EP@1|root,32YDP@2|Bacteria,2GQST@201174|Actinobacteria,4DFB0@85008|Micromonosporales	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3406297_6	1463825.JNXC01000005_gene2483	3.817e-64	230.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4E2ZE@85010|Pseudonocardiales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
SRR25158535_k127_3406297_7	1122611.KB903996_gene7555	2.528e-57	217.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4EP82@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SRR25158535_k127_3406297_11	1045009.AFXQ01000003_gene2717	5.325e-30	136.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,1W8SJ@1268|Micrococcaceae	201174|Actinobacteria	L	NUDIX domain	nudL	-	-	ko:K18568	ko00332,ko01130,map00332,map01130	-	R10747	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
SRR25158535_k127_3406297_5	1122611.KB903996_gene7554	9.229e-66	243.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4EFFN@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
SRR25158535_k127_3406297_9	469371.Tbis_0916	9.655e-37	146.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4E3HX@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
SRR25158535_k127_3406297_0	1123322.KB904663_gene4105	4.658e-132	443.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_3406297_1	1463825.JNXC01000003_gene3589	7.921e-110	376.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DZZ0@85010|Pseudonocardiales	201174|Actinobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
SRR25158535_k127_3406297_4	1298880.AUEV01000006_gene4160	1.147e-73	252.0	COG1884@1|root,COG1884@2|Bacteria,2GM65@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
SRR25158535_k127_3407019_1	177437.HRM2_09320	5.863e-44	164.0	2C56A@1|root,32EMF@2|Bacteria,1NV56@1224|Proteobacteria,42ZEW@68525|delta/epsilon subdivisions,2WV0I@28221|Deltaproteobacteria,2MNCA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3407019_2	28072.Nos7524_0128	1.658e-23	113.0	COG0776@1|root,COG0776@2|Bacteria,1GJY6@1117|Cyanobacteria,1HSVE@1161|Nostocales	1117|Cyanobacteria	L	Bacterial DNA-binding protein	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158535_k127_3407019_0	656024.FsymDg_2726	2.97e-56	208.0	COG3599@1|root,COG3599@2|Bacteria,2H75V@201174|Actinobacteria	201174|Actinobacteria	D	zinc-finger binding domain of transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
SRR25158535_k127_34072_1	479435.Kfla_2107	4.157e-145	482.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2IAS1@201174|Actinobacteria,4DWMF@85009|Propionibacteriales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
SRR25158535_k127_34072_2	675635.Psed_0943	2.152e-102	350.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,4DYKF@85010|Pseudonocardiales	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158535_k127_34072_5	1306174.JODP01000003_gene1783	1.05e-39	154.0	2DRIE@1|root,33BXS@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158535_k127_34072_0	324602.Caur_0806	6.288e-151	486.0	COG3185@1|root,COG3185@2|Bacteria,2G7XQ@200795|Chloroflexi,3765R@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
SRR25158535_k127_34072_8	1184607.AUCHE_08_02680	6.029e-39	153.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4F6TQ@85018|Dermatophilaceae	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SRR25158535_k127_34072_3	653045.Strvi_2217	6.134e-85	303.0	COG0673@1|root,COG0673@2|Bacteria,2GPVY@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_34072_7	1089545.KB913037_gene5143	5.488e-39	153.0	COG3467@1|root,COG3467@2|Bacteria,2I2X2@201174|Actinobacteria,4EBN5@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_34072_4	485913.Krac_4648	1.988e-67	240.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_34072_6	1869.MB27_02655	2.986e-39	151.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4D8I2@85008|Micromonosporales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SRR25158535_k127_3409836_1	1229780.BN381_10199	5.901e-63	238.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3409836_0	1449976.KALB_1118	3.735e-97	323.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4DYEA@85010|Pseudonocardiales	201174|Actinobacteria	D	cell division ATP-binding protein FtsE	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SRR25158535_k127_3409836_2	1184607.AUCHE_08_06370	8.112e-11	68.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4F6CT@85018|Dermatophilaceae	201174|Actinobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SRR25158535_k127_341871_0	390989.JOEG01000016_gene5671	3.287e-286	906.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4D961@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SRR25158535_k127_341871_2	477641.MODMU_3491	1.063e-58	216.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	estB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Lipase_2,PGAP1
SRR25158535_k127_341871_1	2002.JOEQ01000005_gene3671	3.858e-147	482.0	COG1404@1|root,COG1404@2|Bacteria,2IBFK@201174|Actinobacteria,4EMTE@85012|Streptosporangiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
SRR25158535_k127_3421534_0	562970.Btus_2109	2.183e-153	499.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HD8I@91061|Bacilli,2795V@186823|Alicyclobacillaceae	91061|Bacilli	L	Helix-turn-helix domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_3421534_1	1158050.KB895469_gene3144	5.069e-06	52.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,1W83C@1268|Micrococcaceae	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_3428308_5	1137268.AZXF01000009_gene3907	1.307e-44	174.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4EII2@85012|Streptosporangiales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
SRR25158535_k127_3428308_0	561175.KB894099_gene4906	3.845e-132	464.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria,4EGDH@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
SRR25158535_k127_3428308_6	935948.KE386495_gene2119	6.036e-44	184.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,42FE2@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SRR25158535_k127_3428308_7	1380347.JNII01000006_gene1320	3.004e-40	160.0	COG0561@1|root,COG0561@2|Bacteria,2IRCG@201174|Actinobacteria,4EUX0@85013|Frankiales	201174|Actinobacteria	S	Haloacid dehalogenase domain protein hydrolase, type 3	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158535_k127_3428308_3	1380356.JNIK01000002_gene4729	1.585e-82	312.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,4ES7J@85013|Frankiales	201174|Actinobacteria	M	Glycosyltransferase like family 2	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
SRR25158535_k127_3428308_1	1173263.Syn7502_02581	1.829e-120	422.0	COG0498@1|root,COG0498@2|Bacteria,1G0SV@1117|Cyanobacteria,1GZEW@1129|Synechococcus	1117|Cyanobacteria	H	Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_3428308_4	1463855.JOHV01000003_gene2204	2.198e-50	187.0	COG1443@1|root,COG1443@2|Bacteria,2IFK1@201174|Actinobacteria	201174|Actinobacteria	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_3428308_2	585531.HMPREF0063_12015	3.549e-96	326.0	COG1595@1|root,COG1595@2|Bacteria,2GRZW@201174|Actinobacteria,4DSMI@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SRR25158535_k127_3430563_3	1157634.KB912952_gene6107	3.379e-57	204.0	COG3280@1|root,COG3280@2|Bacteria,2GJTB@201174|Actinobacteria	201174|Actinobacteria	G	Malto-oligosyl trehalose synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
SRR25158535_k127_3430563_2	1463920.JOGB01000035_gene6899	1.875e-67	246.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
SRR25158535_k127_3430563_0	1128421.JAGA01000001_gene2004	8.797e-305	972.0	COG1523@1|root,COG1523@2|Bacteria,2NPQU@2323|unclassified Bacteria	2|Bacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SRR25158535_k127_3430563_1	479431.Namu_4887	1.088e-96	355.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4ERC9@85013|Frankiales	201174|Actinobacteria	G	PFAM glycoside hydrolase family 77	malQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SRR25158535_k127_3432410_1	561175.KB894093_gene4395	4.564e-70	241.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4EH97@85012|Streptosporangiales	201174|Actinobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158535_k127_3432410_0	469383.Cwoe_5400	7.515e-134	446.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CPCS@84995|Rubrobacteria	84995|Rubrobacteria	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SRR25158535_k127_3432410_3	1282876.BAOK01000001_gene2756	3.748e-10	71.0	COG4454@1|root,COG4454@2|Bacteria,1RIJK@1224|Proteobacteria,2UIYE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
SRR25158535_k127_3434250_2	68223.JNZY01000003_gene4695	9.943e-11	68.0	COG2172@1|root,COG2172@2|Bacteria,2IFV3@201174|Actinobacteria	201174|Actinobacteria	T	Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158535_k127_3434250_0	446468.Ndas_0959	2.648e-246	800.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4EH6R@85012|Streptosporangiales	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SRR25158535_k127_3434250_1	298654.FraEuI1c_4907	1.21e-112	370.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4ERN9@85013|Frankiales	201174|Actinobacteria	J	PFAM RNA binding S1 domain protein	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SRR25158535_k127_3441853_3	397278.JOJN01000001_gene2665	2.103e-36	150.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4DP1G@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4081)	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
SRR25158535_k127_3441853_0	644284.Arch_0607	2.129e-133	435.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4D394@85005|Actinomycetales	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
SRR25158535_k127_3441853_2	356851.JOAN01000003_gene1722	1.297e-60	234.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4DAZD@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase family M50	rip1	GO:0008150,GO:0040007	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SRR25158535_k127_3441853_1	253839.SSNG_05212	2.355e-112	371.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
SRR25158535_k127_3442237_2	1122611.KB904011_gene6849	1.628e-20	92.0	COG3335@1|root,COG3335@2|Bacteria,2GV6N@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3442237_0	1132441.KI519454_gene226	7.037e-203	651.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
SRR25158535_k127_3442237_1	1435356.Y013_25150	3.918e-131	428.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria,4G3TF@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
SRR25158535_k127_3445914_2	1278078.G419_23319	0.0003314	43.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4G36P@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158535_k127_3445914_1	1380390.JIAT01000013_gene124	1.432e-110	368.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158535_k127_3445914_0	1120949.KB903295_gene2218	2.69e-173	554.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158535_k127_3446061_0	103733.JNYO01000004_gene7776	7.935e-23	99.0	2E3V5@1|root,32YSE@2|Bacteria,2GQM1@201174|Actinobacteria,4E6HJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_23,Sigma70_r4_2
SRR25158535_k127_3446061_1	1288079.AUKN01000017_gene109	2.583e-14	81.0	COG0542@1|root,COG0542@2|Bacteria,2IRV0@201174|Actinobacteria	201174|Actinobacteria	O	Clp domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
SRR25158535_k127_3449064_1	1380347.JNII01000008_gene4060	9.698e-98	323.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4ES0C@85013|Frankiales	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SRR25158535_k127_3449064_0	1146883.BLASA_2361	2.78e-153	506.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4ERCY@85013|Frankiales	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SRR25158535_k127_3449064_2	710111.FraQA3DRAFT_6299	3.702e-10	67.0	COG0505@1|root,COG0505@2|Bacteria,2GM9I@201174|Actinobacteria	201174|Actinobacteria	EF	Belongs to the CarA family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3453295_7	1246474.ANBE01000049_gene1417	1.802e-19	94.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4EGP3@85012|Streptosporangiales	201174|Actinobacteria	J	Ribosomal protein S2	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SRR25158535_k127_3453295_3	935948.KE386494_gene260	4.038e-64	226.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SRR25158535_k127_3453295_1	1463917.JODC01000014_gene2118	3.828e-94	316.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SRR25158535_k127_3453295_4	351607.Acel_1539	1.611e-63	234.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4ESC9@85013|Frankiales	201174|Actinobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SRR25158535_k127_3453295_6	1380393.JHVP01000021_gene178	2.681e-42	174.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4EXIS@85013|Frankiales	201174|Actinobacteria	I	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SRR25158535_k127_3453295_5	414996.IL38_22505	4.295e-48	186.0	COG1943@1|root,COG1943@2|Bacteria,2IMQ2@201174|Actinobacteria,40A93@622450|Actinopolysporales	201174|Actinobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
SRR25158535_k127_3453295_0	247156.NFA_15170	1.415e-134	463.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4FXXV@85025|Nocardiaceae	201174|Actinobacteria	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_3453295_2	326427.Cagg_0286	6.566e-78	272.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,374VF@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SRR25158535_k127_3454855_5	345341.KUTG_07606	2.586e-08	57.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E23Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR25158535_k127_3454855_2	106370.Francci3_2197	5.825e-32	128.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
SRR25158535_k127_3454855_0	106370.Francci3_2088	1.035e-183	588.0	COG1961@1|root,COG1961@2|Bacteria,2INJA@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_3454855_1	106370.Francci3_2088	3.276e-55	204.0	COG1961@1|root,COG1961@2|Bacteria,2INJA@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_3454855_3	222534.KB893713_gene2384	8.187e-27	109.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,Intron_maturas2,RVT_1
SRR25158535_k127_3457447_0	266117.Rxyl_2657	3.524e-74	254.0	COG2159@1|root,COG2159@2|Bacteria,2I9CM@201174|Actinobacteria,4CRK1@84995|Rubrobacteria	201174|Actinobacteria	S	amidohydrolase 2	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158535_k127_3457447_2	326427.Cagg_3149	4.659e-29	119.0	COG2151@1|root,COG2151@2|Bacteria,2GB51@200795|Chloroflexi,377A6@32061|Chloroflexia	32061|Chloroflexia	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SRR25158535_k127_3457447_1	408672.NBCG_02533	4.969e-66	235.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
SRR25158535_k127_3458492_1	525904.Tter_2084	1.709e-33	133.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	CBS
SRR25158535_k127_3458492_4	1211815.CBYP010000062_gene3178	6.563e-13	70.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SRR25158535_k127_3458492_0	1347086.CCBA010000007_gene4533	3.137e-34	138.0	2DNQ4@1|root,32YIU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SUKH_6
SRR25158535_k127_3458492_2	465817.ETA_08660	2.11e-17	93.0	COG3209@1|root,COG4104@1|root,COG3209@2|Bacteria,COG4104@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,3X5EE@551|Erwinia	1236|Gammaproteobacteria	M	silverDB	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif,RHS,RHS_repeat,Tox-HNH-EHHH
SRR25158535_k127_3458492_3	749927.AMED_6611	5.977e-14	74.0	COG3689@1|root,COG3689@2|Bacteria,2GNFK@201174|Actinobacteria,4E2XB@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF1980)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1980
SRR25158535_k127_3458798_0	1120949.KB903295_gene2218	1.219e-86	289.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
SRR25158535_k127_3458798_1	1380390.JIAT01000010_gene4392	2.005e-83	289.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_3460392_1	35754.JNYJ01000014_gene4734	3.696e-19	92.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4DDF0@85008|Micromonosporales	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_3460392_0	1121472.AQWN01000003_gene1419	2.593e-171	576.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25ZY7@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SRR25158535_k127_3464380_4	1382356.JQMP01000003_gene1716	7.486e-14	85.0	COG0154@1|root,COG0154@2|Bacteria,2G82J@200795|Chloroflexi,27XKT@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SRR25158535_k127_3464380_2	469383.Cwoe_5791	3.162e-89	300.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,4CPSB@84995|Rubrobacteria	84995|Rubrobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SRR25158535_k127_3464380_3	1125971.ASJB01000043_gene3222	5.843e-37	148.0	COG3654@1|root,COG3654@2|Bacteria,2IR34@201174|Actinobacteria,4E4RS@85010|Pseudonocardiales	201174|Actinobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
SRR25158535_k127_3464380_5	526226.Gbro_0423	8.603e-13	70.0	2EM5W@1|root,33EV5@2|Bacteria,2GT38@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158535_k127_3464380_0	929712.KI912613_gene1492	2.066e-239	790.0	COG1061@1|root,COG1061@2|Bacteria,2GNGE@201174|Actinobacteria	201174|Actinobacteria	KL	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
SRR25158535_k127_3464380_1	512565.AMIS_12470	3.055e-126	413.0	COG5586@1|root,COG5586@2|Bacteria,2GX58@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
SRR25158535_k127_3471374_3	665577.JH993790_gene5690	2.942e-31	126.0	COG3335@1|root,COG3335@2|Bacteria,2I9RW@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3
SRR25158535_k127_3471374_0	222534.KB893730_gene5762	0.0	1125.0	COG1961@1|root,COG1961@2|Bacteria,2ID9R@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_3471374_4	1206725.BAFU01000219_gene12	1.183e-06	52.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3471374_2	1194165.CAJF01000023_gene3158	7.093e-71	246.0	COG0739@1|root,COG0739@2|Bacteria,2I9IY@201174|Actinobacteria	201174|Actinobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SRR25158535_k127_3471374_1	1038859.AXAU01000013_gene6552	5.299e-169	536.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2TWC9@28211|Alphaproteobacteria,3JVP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158535_k127_3478443_5	1968.JOEV01000115_gene3861	5.12e-11	65.0	COG3415@1|root,COG3415@2|Bacteria,2I2W7@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
SRR25158535_k127_3478443_1	1128421.JAGA01000003_gene3009	3.524e-91	310.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,SGL,VCBS
SRR25158535_k127_3478443_4	1196324.A374_08484	1.237e-21	107.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli	91061|Bacilli	M	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K01802,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
SRR25158535_k127_3478443_2	756499.Desde_0103	1.731e-66	253.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
SRR25158535_k127_3478443_0	1121380.JNIW01000014_gene2484	2.011e-178	575.0	COG0148@1|root,COG0148@2|Bacteria,1WIST@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
SRR25158535_k127_3478443_3	404589.Anae109_2167	4.349e-35	136.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJEI@28221|Deltaproteobacteria,2Z2X3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
SRR25158535_k127_3484486_5	477641.MODMU_3897	4.035e-07	52.0	COG1033@1|root,COG2409@1|root,COG1033@2|Bacteria,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria,4EURS@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_3484486_3	1120949.KB903356_gene8730	4.11e-17	96.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DCDG@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_3484486_0	469383.Cwoe_0605	3.098e-97	336.0	COG2909@1|root,COG2909@2|Bacteria,2HF4A@201174|Actinobacteria,4CSVM@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
SRR25158535_k127_3484486_1	68170.KL590508_gene11408	7.883e-83	281.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4E3G7@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_3484486_4	68170.KL590508_gene11412	1.034e-15	90.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_3484486_2	1380390.JIAT01000011_gene2333	1.555e-63	228.0	COG3447@1|root,COG4585@1|root,COG3447@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,Guanylate_cyc,HATPase_c,HisKA,HisKA_3,MASE1,PAS,PAS_3,PAS_9
SRR25158535_k127_3484563_3	1122182.KB903834_gene6119	1.28e-06	54.0	COG1848@1|root,COG1848@2|Bacteria,2IJ8I@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158535_k127_3484563_1	365528.KB891252_gene5608	1.745e-44	170.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4ESM1@85013|Frankiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SRR25158535_k127_3484563_0	365528.KB891252_gene5607	2.321e-53	190.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4ESPE@85013|Frankiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SRR25158535_k127_3484563_2	222534.KB893739_gene1353	1.919e-25	111.0	COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4ES8S@85013|Frankiales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SRR25158535_k127_3510164_1	222534.KB893726_gene349	1.42e-86	300.0	COG3291@1|root,COG3291@2|Bacteria,2IC29@201174|Actinobacteria,4ESQF@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4394)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394
SRR25158535_k127_3510164_0	1380356.JNIK01000001_gene2104	1.456e-170	563.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4ESAG@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_3510164_2	248742.XP_005652207.1	2.841e-12	81.0	COG0561@1|root,2S1YA@2759|Eukaryota,388N7@33090|Viridiplantae,34JF1@3041|Chlorophyta	3041|Chlorophyta	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SRR25158535_k127_3517634_1	2074.JNYD01000024_gene2905	1.963e-21	98.0	COG3547@1|root,COG3547@2|Bacteria,2H4P5@201174|Actinobacteria,4EF3E@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110
SRR25158535_k127_3517634_0	656024.FsymDg_1390	6.332e-58	207.0	COG3415@1|root,COG3415@2|Bacteria,2IJUQ@201174|Actinobacteria	201174|Actinobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
SRR25158535_k127_3751_9	390989.JOEG01000012_gene3416	1.293e-80	278.0	COG0122@1|root,COG0122@2|Bacteria,2GP69@201174|Actinobacteria,4D9BH@85008|Micromonosporales	201174|Actinobacteria	L	3-methyladenine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_3751_7	351607.Acel_1503	2.924e-92	313.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4ERIQ@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SRR25158535_k127_3751_0	1122182.KB903839_gene1109	2.195e-189	608.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4DCFB@85008|Micromonosporales	201174|Actinobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SRR25158535_k127_3751_8	1121468.AUBR01000009_gene2169	2.822e-91	338.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,42EM0@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SRR25158535_k127_3751_11	264732.Moth_1073	8.698e-28	122.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,42J4X@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
SRR25158535_k127_3751_2	1089548.KI783301_gene3204	2.161e-126	421.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3WE8U@539002|Bacillales incertae sedis	91061|Bacilli	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
SRR25158535_k127_3751_10	1123322.KB904658_gene1355	5.301e-64	225.0	COG1309@1|root,COG1309@2|Bacteria,2IKQ8@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_3751_3	469383.Cwoe_4781	3.517e-118	397.0	COG0477@1|root,COG2271@1|root,COG0477@2|Bacteria,COG2271@2|Bacteria,2I31V@201174|Actinobacteria,4CPF3@84995|Rubrobacteria	201174|Actinobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_3751_5	196162.Noca_2319	3.255e-108	389.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,4DNHY@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
SRR25158535_k127_3751_6	351607.Acel_1497	4.269e-108	377.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4ERZM@85013|Frankiales	201174|Actinobacteria	S	Belongs to the CinA family	cinA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SRR25158535_k127_3751_12	290397.Adeh_3960	2.37e-21	107.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SRR25158535_k127_3751_1	743718.Isova_1246	1.057e-158	512.0	COG0468@1|root,COG1372@1|root,COG0468@2|Bacteria,COG1372@2|Bacteria,2GJ4P@201174|Actinobacteria,4F38E@85017|Promicromonosporaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158535_k127_3751_4	1370120.AUWR01000013_gene3352	5.004e-111	366.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,232KV@1762|Mycobacteriaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158535_k127_376548_0	656024.FsymDg_3799	1.256e-305	1000.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4ES7U@85013|Frankiales	201174|Actinobacteria	G	PFAM glycosyl transferase, family 35	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SRR25158535_k127_376548_6	1463901.JOIY01000051_gene6377	1.546e-29	126.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_376548_5	469371.Tbis_0054	1.051e-61	233.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2GMPZ@201174|Actinobacteria,4DY16@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_376548_4	266117.Rxyl_2353	1.884e-73	251.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4CSPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
SRR25158535_k127_376548_1	326424.FRAAL5899	4.367e-263	831.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4ERHA@85013|Frankiales	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SRR25158535_k127_376548_3	298654.FraEuI1c_0966	1.985e-82	294.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4ERHN@85013|Frankiales	201174|Actinobacteria	G	protein, probably involved in trehalose biosynthesis	treX	-	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SRR25158535_k127_376548_2	298654.FraEuI1c_0965	4.193e-142	460.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4ERUN@85013|Frankiales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SRR25158535_k127_381617_3	1122939.ATUD01000002_gene1170	4.141e-11	74.0	COG0789@1|root,COG2114@1|root,COG0789@2|Bacteria,COG2114@2|Bacteria,2ICT6@201174|Actinobacteria,4CR4V@84995|Rubrobacteria	84995|Rubrobacteria	KT	Adenylate cyclase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	Ad_Cy_reg,Guanylate_cyc,MerR_1
SRR25158535_k127_381617_1	1151119.KB895492_gene1596	1.155e-12	79.0	COG1028@1|root,COG1028@2|Bacteria,2GX9R@201174|Actinobacteria	201174|Actinobacteria	IQ	short-chain dehydrogenase	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
SRR25158535_k127_381617_0	1380370.JIBA01000012_gene3752	3.28e-60	220.0	COG0778@1|root,COG0778@2|Bacteria,2HG9J@201174|Actinobacteria,4FJR4@85021|Intrasporangiaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SRR25158535_k127_381617_2	710685.MycrhN_0775	3.651e-12	72.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria,23F97@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_387502_0	351607.Acel_0304	2.651e-210	662.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4ERZ7@85013|Frankiales	201174|Actinobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SRR25158535_k127_387502_6	411684.HPDFL43_03841	1.889e-17	88.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,2U9WH@28211|Alphaproteobacteria,43RDV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SRR25158535_k127_387502_4	298654.FraEuI1c_6175	8.476e-24	105.0	COG1846@1|root,COG1846@2|Bacteria,2II46@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF742)	cvnC6	-	-	-	-	-	-	-	-	-	-	-	DUF742
SRR25158535_k127_387502_3	656024.FsymDg_0502	6.122e-117	406.0	COG0642@1|root,COG0642@2|Bacteria,2GKY7@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158535_k127_387502_1	1150864.MILUP08_42123	1.828e-196	643.0	COG2909@1|root,COG2909@2|Bacteria,2GM03@201174|Actinobacteria,4D9RB@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,GerE
SRR25158535_k127_387502_2	1120949.KB903299_gene6015	7.016e-127	421.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SRR25158535_k127_387502_5	1121946.AUAX01000017_gene5088	8.485e-18	92.0	COG1714@1|root,COG1714@2|Bacteria,2HWUK@201174|Actinobacteria,4DKDX@85008|Micromonosporales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SRR25158535_k127_387502_7	1123024.AUII01000028_gene2486	8.418e-10	59.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2GN0H@201174|Actinobacteria,4E3TF@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
SRR25158535_k127_390311_3	326424.FRAAL6865	5.832e-89	332.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4ERF4@85013|Frankiales	201174|Actinobacteria	KLT	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
SRR25158535_k127_390311_4	656024.FsymDg_4536	2.427e-43	182.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4ESX8@85013|Frankiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_390311_5	1273125.Rrhod_2932	2.916e-30	132.0	COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4FW1B@85025|Nocardiaceae	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_390311_7	1451261.AS96_12675	8.791e-07	57.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria,4FNY7@85023|Microbacteriaceae	201174|Actinobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158535_k127_390311_6	351160.RRC310	1.181e-11	78.0	COG3729@1|root,arCOG10926@2157|Archaea	2157|Archaea	S	general stress protein B in uncultured methanogenic archaeon (Q0W564)	-	-	-	-	-	-	-	-	-	-	-	-	LEA_5
SRR25158535_k127_390311_2	1463854.JOHT01000003_gene6158	9.508e-174	558.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
SRR25158535_k127_390311_0	649831.L083_2860	1.956e-194	622.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4D8SF@85008|Micromonosporales	2|Bacteria	G	alpha amylase, catalytic	-	-	3.2.1.10,3.2.1.20,3.2.1.93	ko:K01182,ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R00837,R01718,R01791,R06087,R06088,R06113,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
SRR25158535_k127_390311_1	656024.FsymDg_4531	1.628e-181	576.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4ERYP@85013|Frankiales	201174|Actinobacteria	I	PFAM Myo-inositol-1-phosphate synthase	ino1	GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
SRR25158535_k127_394441_0	643648.Slip_0897	1.653e-111	381.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,42JJA@68298|Syntrophomonadaceae	186801|Clostridia	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
SRR25158535_k127_394441_8	479431.Namu_4645	1.788e-21	104.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4ET9G@85013|Frankiales	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SRR25158535_k127_394441_3	882082.SaccyDRAFT_0375	2.251e-93	332.0	COG0455@1|root,COG0455@2|Bacteria,2GMK0@201174|Actinobacteria,4DXEP@85010|Pseudonocardiales	201174|Actinobacteria	D	ATPase involved in chromosome	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
SRR25158535_k127_394441_1	43759.JNWK01000007_gene1783	9.327e-106	351.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria	201174|Actinobacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158535_k127_394441_2	298655.KI912266_gene1784	8.39e-97	331.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4ERWC@85013|Frankiales	201174|Actinobacteria	H	MoeA domain protein domain I and II	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1,2.7.7.9	ko:K00963,ko:K03750	ko00040,ko00052,ko00500,ko00520,ko00790,ko01100,ko01130,map00040,map00052,map00500,map00520,map00790,map01100,map01130	M00129,M00361,M00362,M00549	R00289,R09735	RC00002,RC03462	ko00000,ko00001,ko00002,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SRR25158535_k127_394441_5	298654.FraEuI1c_0543	1.494e-47	194.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4ESM0@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
SRR25158535_k127_394441_7	1111479.AXAR01000010_gene2612	1.887e-35	152.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,4HHPP@91061|Bacilli,278GY@186823|Alicyclobacillaceae	91061|Bacilli	H	Probable molybdopterin binding domain	moaB	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SRR25158535_k127_394441_6	1237500.ANBA01000004_gene2160	7.956e-37	143.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4EQ3W@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158535_k127_394441_9	1348663.KCH_44130	4.117e-14	79.0	COG1846@1|root,COG1846@2|Bacteria,2II5E@201174|Actinobacteria,2M5G1@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158535_k127_394441_4	706587.Desti_1188	3.003e-58	205.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,42Q5R@68525|delta/epsilon subdivisions,2WM6U@28221|Deltaproteobacteria,2MR4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158535_k127_396501_1	1304865.JAGF01000001_gene634	1.654e-51	183.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4F1S5@85016|Cellulomonadaceae	201174|Actinobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
SRR25158535_k127_396501_2	471852.Tcur_0588	1.917e-51	194.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4EGZ9@85012|Streptosporangiales	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SRR25158535_k127_396501_0	1379698.RBG1_1C00001G0364	6.36e-88	298.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SRR25158535_k127_398727_3	926569.ANT_28040	1.414e-107	357.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi	200795|Chloroflexi	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
SRR25158535_k127_398727_0	1283283.ATXA01000007_gene3834	1.704e-201	640.0	COG3845@1|root,COG3845@2|Bacteria,2H7KJ@201174|Actinobacteria,4ES4A@85013|Frankiales	201174|Actinobacteria	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
SRR25158535_k127_398727_1	1120950.KB892760_gene5784	6.222e-125	413.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,4DNPP@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158535_k127_398727_2	390989.JOEG01000023_gene5747	1.488e-117	401.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria,4D974@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SRR25158535_k127_398727_4	1304877.KI519399_gene3460	1.749e-07	55.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,3JQYV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SRR25158535_k127_400066_0	948106.AWZT01000036_gene1735	5.997e-91	320.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2W9DD@28216|Betaproteobacteria,1K59C@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SRR25158535_k127_400066_1	1120948.KB903247_gene4535	3.3e-81	276.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,4DY1J@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
SRR25158535_k127_404687_4	749414.SBI_09016	1.986e-17	83.0	COG1132@1|root,COG1132@2|Bacteria,2GKE4@201174|Actinobacteria	201174|Actinobacteria	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_404687_1	1463917.JODC01000007_gene7779	4.683e-121	399.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria	201174|Actinobacteria	S	Low temperature requirement	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
SRR25158535_k127_404687_0	710111.FraQA3DRAFT_3420	1.173e-156	500.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4ES6V@85013|Frankiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase (Decarboxylating)	gnd2	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1122	6PGD,NAD_binding_2
SRR25158535_k127_404687_2	351607.Acel_1804	7.055e-87	294.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4ESGH@85013|Frankiales	201174|Actinobacteria	K	UbiC transcription regulator-associated domain protein	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SRR25158535_k127_404687_3	1463901.JOIY01000072_gene6446	3.218e-60	210.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria	201174|Actinobacteria	G	PFAM PfkB domain protein	iolC	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158535_k127_40749_1	469371.Tbis_1904	4.415e-61	228.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DXXX@85010|Pseudonocardiales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_40749_0	285535.JOEY01000024_gene313	9.007e-107	358.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_408542_3	1123023.JIAI01000004_gene7831	2.961e-15	77.0	COG3301@1|root,COG3301@2|Bacteria	2|Bacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SRR25158535_k127_408542_1	656024.FsymDg_4205	2.415e-83	304.0	COG1108@1|root,COG1108@2|Bacteria,2IGW9@201174|Actinobacteria,4EXA0@85013|Frankiales	201174|Actinobacteria	P	ABC 3 transport family	yfeD	-	-	ko:K02075,ko:K09819	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
SRR25158535_k127_408542_0	656024.FsymDg_4206	3.173e-85	299.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4ETAC@85013|Frankiales	201174|Actinobacteria	P	PFAM ABC-3 protein	yfeC	-	-	ko:K02075,ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SRR25158535_k127_408542_2	298655.KI912266_gene1081	2.84e-75	256.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,4ET4X@85013|Frankiales	201174|Actinobacteria	P	pfam abc	yfeB	-	-	ko:K02074,ko:K09820,ko:K11710	ko02010,map02010	M00243,M00244,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
SRR25158535_k127_412352_3	1996.JOFO01000025_gene4356	6.604e-35	137.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4EG6G@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_primase_S
SRR25158535_k127_412352_1	471852.Tcur_3711	6.233e-63	231.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4EH5H@85012|Streptosporangiales	201174|Actinobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
SRR25158535_k127_412352_0	1068978.AMETH_3262	5.549e-90	317.0	COG1597@1|root,COG1597@2|Bacteria,2GNNM@201174|Actinobacteria,4E8M5@85010|Pseudonocardiales	201174|Actinobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158535_k127_412352_2	561175.KB894093_gene2664	2.751e-55	199.0	COG0697@1|root,COG0697@2|Bacteria,2GS88@201174|Actinobacteria,4EGHN@85012|Streptosporangiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_41410_7	1380390.JIAT01000011_gene2864	6.823e-43	171.0	2A4ZY@1|root,30KGA@2|Bacteria,2HRSX@201174|Actinobacteria,4CTW6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_41410_5	1380390.JIAT01000011_gene2864	7.495e-75	275.0	2A4ZY@1|root,30KGA@2|Bacteria,2HRSX@201174|Actinobacteria,4CTW6@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_41410_11	867903.ThesuDRAFT_00714	1.725e-27	115.0	COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes	1239|Firmicutes	S	Ethyl tert-butyl ether degradation	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
SRR25158535_k127_41410_6	994479.GL877878_gene1939	4.153e-66	240.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4DYVB@85010|Pseudonocardiales	201174|Actinobacteria	I	PFAM Enoyl-CoA hydratase isomerase	chcB	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
SRR25158535_k127_41410_0	644282.Deba_1258	8.325e-151	497.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh,Fe-ADH
SRR25158535_k127_41410_2	981369.JQMJ01000004_gene449	1.346e-89	327.0	COG0842@1|root,COG0842@2|Bacteria,2HNB6@201174|Actinobacteria,2NHZ8@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SRR25158535_k127_41410_4	1125971.ASJB01000099_gene2287	5.342e-75	267.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria,4E1XJ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SRR25158535_k127_41410_1	1125971.ASJB01000099_gene2288	9.605e-121	402.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4E1YQ@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_41410_14	134676.ACPL_7222	6.832e-19	96.0	2ARQJ@1|root,31H1M@2|Bacteria,2IG4U@201174|Actinobacteria,4DD1P@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_41410_15	1206743.BAGM01000049_gene1195	4.044e-16	90.0	COG4244@1|root,COG4244@2|Bacteria,2II9W@201174|Actinobacteria,4G94C@85025|Nocardiaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
SRR25158535_k127_41410_10	909613.UO65_3501	3.394e-34	138.0	COG3427@1|root,COG3427@2|Bacteria,2II8Y@201174|Actinobacteria,4E5GT@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SRR25158535_k127_41410_3	33876.JNXY01000039_gene6529	2.512e-89	335.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4D9P0@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SRR25158535_k127_41410_9	1089548.KI783301_gene1505	3.058e-36	142.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,3WFQF@539002|Bacillales incertae sedis	91061|Bacilli	S	CoA binding domain	yneT	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SRR25158535_k127_41410_13	101510.RHA1_ro03365	4.039e-25	110.0	COG0406@1|root,COG0406@2|Bacteria,2GXA4@201174|Actinobacteria,4G6UB@85025|Nocardiaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
SRR25158535_k127_41410_12	870187.Thini_0347	2.361e-26	111.0	COG3411@1|root,COG3411@2|Bacteria,1N0XK@1224|Proteobacteria,1S9F8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_41410_16	1246995.AFR_32060	1.346e-10	69.0	2DRJD@1|root,33C0U@2|Bacteria,2IQVG@201174|Actinobacteria,4DEXW@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_41410_8	1229780.BN381_310078	3.554e-39	149.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
SRR25158535_k127_418203_1	526225.Gobs_3501	4.673e-86	293.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
SRR25158535_k127_418203_0	234621.RER_11890	2.72e-140	454.0	COG0560@1|root,COG0560@2|Bacteria,2GKRQ@201174|Actinobacteria,4FXGP@85025|Nocardiaceae	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
SRR25158535_k127_418203_2	1380390.JIAT01000011_gene2349	1.458e-45	168.0	2DS2T@1|root,33E9A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4239
SRR25158535_k127_420905_0	285535.JOEY01000024_gene273	8.714e-266	834.0	COG0793@1|root,COG0793@2|Bacteria,2HFZM@201174|Actinobacteria	201174|Actinobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
SRR25158535_k127_423795_1	1246995.AFR_20685	1.616e-112	366.0	COG0524@1|root,COG0524@2|Bacteria,2GM3N@201174|Actinobacteria,4DBGZ@85008|Micromonosporales	201174|Actinobacteria	G	pfkB family carbohydrate kinase	iolC	-	2.7.1.45,2.7.1.92	ko:K00874,ko:K03338	ko00030,ko00562,ko01100,ko01120,ko01200,map00030,map00562,map01100,map01120,map01200	M00061,M00308,M00631	R01541,R05661	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SRR25158535_k127_423795_0	1123023.JIAI01000021_gene2367	9.439e-133	430.0	COG1830@1|root,COG1830@2|Bacteria,2GKTN@201174|Actinobacteria,4DYYW@85010|Pseudonocardiales	201174|Actinobacteria	G	deoxyribose-phosphate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_427711_1	1150864.MILUP08_45409	1.072e-29	124.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158535_k127_427711_2	47839.CCAU010000005_gene481	2.448e-15	85.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,2366A@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158535_k127_427711_0	1197906.CAJQ02000046_gene3822	3.834e-32	138.0	2E54J@1|root,32ZXH@2|Bacteria,1R9DG@1224|Proteobacteria,2U2YG@28211|Alphaproteobacteria,3JR4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_433553_1	28444.JODQ01000006_gene454	5.654e-47	171.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4EN0M@85012|Streptosporangiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SRR25158535_k127_433553_3	101510.RHA1_ro03279	1.913e-17	96.0	COG0654@1|root,COG0654@2|Bacteria,2GJ9V@201174|Actinobacteria,4FTXP@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158535_k127_433553_0	298653.Franean1_3948	3.126e-105	353.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria,4EVQ7@85013|Frankiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SRR25158535_k127_433553_4	446470.Snas_6234	5.483e-07	56.0	COG0582@1|root,COG2188@1|root,COG0582@2|Bacteria,COG2188@2|Bacteria,2I9QS@201174|Actinobacteria,4EZX7@85014|Glycomycetales	201174|Actinobacteria	K	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158535_k127_433553_5	1907.SGLAU_33205	0.0006317	43.0	COG3293@1|root,COG3293@2|Bacteria,2IIB4@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
SRR25158535_k127_433553_2	227882.SAV_4680	1.436e-20	100.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_434472_0	351607.Acel_1142	5.777e-209	665.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4ERSA@85013|Frankiales	201174|Actinobacteria	V	ABC transporter, transmembrane region	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SRR25158535_k127_434472_2	1463821.JOGR01000006_gene2761	1.042e-129	428.0	COG0624@1|root,COG0624@2|Bacteria,2GJDE@201174|Actinobacteria,4EXXW@85014|Glycomycetales	201174|Actinobacteria	E	Peptidase family M28	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_434472_1	58123.JOFJ01000003_gene2168	7.077e-164	529.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria,4EHFN@85012|Streptosporangiales	201174|Actinobacteria	F	Amidohydrolase family	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_434472_5	266117.Rxyl_0446	2.465e-52	205.0	COG3428@1|root,COG3428@2|Bacteria,2GJCD@201174|Actinobacteria,4CQ5Y@84995|Rubrobacteria	84995|Rubrobacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158535_k127_434472_6	518766.Rmar_2116	5.142e-20	96.0	COG3402@1|root,COG3402@2|Bacteria,4NUVJ@976|Bacteroidetes,1FJHV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
SRR25158535_k127_434472_3	1394178.AWOO02000086_gene1014	9.043e-125	407.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4EHGZ@85012|Streptosporangiales	201174|Actinobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
SRR25158535_k127_434472_4	309807.SRU_0721	5.882e-115	401.0	COG1232@1|root,COG1232@2|Bacteria,4NEPC@976|Bacteroidetes,1FJ99@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SRR25158535_k127_437878_1	477641.MODMU_0384	1.196e-31	133.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4ERY8@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_437878_0	329726.AM1_2452	2.962e-251	824.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158535_k127_447344_0	298654.FraEuI1c_1957	2.574e-174	551.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4ES3S@85013|Frankiales	201174|Actinobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158535_k127_447344_1	298654.FraEuI1c_1956	5.099e-55	196.0	COG0105@1|root,COG0105@2|Bacteria,2IFBU@201174|Actinobacteria,4ESUM@85013|Frankiales	201174|Actinobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	iNJ661.Rv2445c	NDK
SRR25158535_k127_449489_3	749414.SBI_05880	2.904e-53	214.0	COG2197@1|root,COG3829@1|root,COG4585@1|root,COG2197@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,2IAG1@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
SRR25158535_k127_449489_4	269797.Mbar_A3082	5.31e-50	183.0	COG4894@1|root,arCOG03995@2157|Archaea,2XXXJ@28890|Euryarchaeota,2NB1N@224756|Methanomicrobia	224756|Methanomicrobia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
SRR25158535_k127_449489_6	590998.Celf_3178	1.33e-22	98.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4F2SB@85016|Cellulomonadaceae	201174|Actinobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_449489_5	68570.DC74_4007	1.248e-48	184.0	2BPHM@1|root,32IA4@2|Bacteria,2GM2J@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_449489_0	1120973.AQXL01000131_gene2039	6.391e-125	410.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27949@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158535_k127_449489_1	351607.Acel_2071	1.892e-103	356.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4ERKV@85013|Frankiales	201174|Actinobacteria	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SRR25158535_k127_449489_2	1122611.KB903964_gene4928	4.624e-73	249.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4EGDA@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
SRR25158535_k127_457173_2	644283.Micau_5071	1.612e-86	296.0	COG0010@1|root,COG0010@2|Bacteria,2H81I@201174|Actinobacteria,4D8G7@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the arginase family	argI	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
SRR25158535_k127_457173_0	1120950.KB892747_gene3669	3.055e-188	597.0	COG0520@1|root,COG0520@2|Bacteria,2GKAF@201174|Actinobacteria,4DN1Z@85009|Propionibacteriales	201174|Actinobacteria	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SRR25158535_k127_457173_1	926569.ANT_18620	2.983e-165	525.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_458453_1	58123.JOFJ01000027_gene2790	1.369e-185	589.0	COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4EN0D@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SRR25158535_k127_458453_3	324602.Caur_2081	3.041e-89	314.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SRR25158535_k127_458453_6	1386089.N865_02200	1.937e-29	132.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4FEIT@85021|Intrasporangiaceae	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SRR25158535_k127_458453_4	1449347.JQLN01000007_gene1817	6.03e-47	186.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,2M4FI@2063|Kitasatospora	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_458453_2	1278073.MYSTI_01297	7.625e-170	560.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
SRR25158535_k127_458453_0	1382356.JQMP01000003_gene1584	5.891e-313	990.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
SRR25158535_k127_458453_5	1120949.KB903299_gene5867	6.354e-31	133.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria,4DMV6@85008|Micromonosporales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_458453_7	345341.KUTG_00547	4.946e-14	73.0	COG3448@1|root,COG3448@2|Bacteria,2I3G0@201174|Actinobacteria,4E3DH@85010|Pseudonocardiales	201174|Actinobacteria	T	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
SRR25158535_k127_458467_0	1122138.AQUZ01000068_gene2438	0.0	1086.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,4DTEN@85009|Propionibacteriales	201174|Actinobacteria	L	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
SRR25158535_k127_458467_1	419947.MRA_2826	6.489e-05	57.0	COG5586@1|root,COG5586@2|Bacteria,2GX58@201174|Actinobacteria,237WQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
SRR25158535_k127_46233_0	1394178.AWOO02000028_gene5385	9.807e-207	660.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4EGVR@85012|Streptosporangiales	201174|Actinobacteria	L	DNA ligase N terminus	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158535_k127_46233_9	1214242.B446_24800	1.365e-64	245.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SRR25158535_k127_46233_10	471852.Tcur_3678	9.41e-47	189.0	COG1695@1|root,COG1695@2|Bacteria,2GMKD@201174|Actinobacteria,4EGI8@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_46233_12	1449068.JMLQ01000006_gene1674	6.177e-40	153.0	COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria,4G1BR@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
SRR25158535_k127_46233_6	471852.Tcur_1631	3.872e-95	338.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria,4EFUQ@85012|Streptosporangiales	201174|Actinobacteria	P	Rhodanese Homology Domain	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
SRR25158535_k127_46233_4	1394178.AWOO02000088_gene962	8.969e-103	347.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4EGT7@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
SRR25158535_k127_46233_5	1394178.AWOO02000088_gene963	6.369e-100	349.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EHS4@85012|Streptosporangiales	201174|Actinobacteria	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_46233_13	1382306.JNIM01000001_gene539	1.271e-20	97.0	2EIKM@1|root,33CBX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_46233_8	204669.Acid345_3293	2.474e-73	269.0	COG0665@1|root,COG0665@2|Bacteria,3Y5BS@57723|Acidobacteria,2JK99@204432|Acidobacteriia	204432|Acidobacteriia	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303,ko:K21061	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R00610,R11428	RC00060,RC00135,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
SRR25158535_k127_46233_11	67352.JODS01000025_gene3176	3.268e-46	174.0	COG1309@1|root,COG1309@2|Bacteria,2GJXV@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
SRR25158535_k127_46233_1	1449353.JQMQ01000005_gene1798	9.315e-206	653.0	COG0477@1|root,COG0477@2|Bacteria,2IBIG@201174|Actinobacteria,2NHKA@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_46233_2	1123322.KB904634_gene2353	2.112e-113	389.0	COG3386@1|root,COG3386@2|Bacteria,2GNV1@201174|Actinobacteria	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
SRR25158535_k127_46233_7	67332.FM21_06140	1.708e-93	316.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158535_k127_46233_3	469383.Cwoe_5124	2.186e-111	387.0	COG0826@1|root,COG0826@2|Bacteria,2GKAK@201174|Actinobacteria,4CSIM@84995|Rubrobacteria	84995|Rubrobacteria	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
SRR25158535_k127_46233_14	1125971.ASJB01000099_gene2395	1.276e-10	64.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4E4VR@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_467689_3	477641.MODMU_4596	2.114e-16	79.0	COG3860@1|root,COG3860@2|Bacteria,2IQEK@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20
SRR25158535_k127_467689_1	1229780.BN381_210060	8.532e-59	229.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,3UWQH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	endonuclease III	mutY	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SRR25158535_k127_467689_2	351607.Acel_0107	4.982e-45	181.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4ERU5@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_467689_0	1123251.ATWM01000007_gene2399	3.861e-101	334.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4FES5@85021|Intrasporangiaceae	201174|Actinobacteria	O	ATP-dependent Clp protease	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
SRR25158535_k127_468682_0	469383.Cwoe_0722	1.775e-114	377.0	COG2060@1|root,COG2060@2|Bacteria,2GK51@201174|Actinobacteria,4CRJ1@84995|Rubrobacteria	84995|Rubrobacteria	P	Potassium-transporting ATPase A subunit	-	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SRR25158535_k127_468682_2	929712.KI912613_gene2733	7.79e-74	269.0	COG2156@1|root,COG2156@2|Bacteria,2GK75@201174|Actinobacteria,4CSNC@84995|Rubrobacteria	84995|Rubrobacteria	P	K+-transporting ATPase, c chain	-	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SRR25158535_k127_468682_1	469383.Cwoe_0724	2.075e-97	335.0	COG2216@1|root,COG2216@2|Bacteria,2GIWT@201174|Actinobacteria,4CRFC@84995|Rubrobacteria	84995|Rubrobacteria	P	E1-E2 ATPase	-	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
SRR25158535_k127_469233_5	743718.Isova_1831	2.556e-29	121.0	COG1104@1|root,COG1104@2|Bacteria,2GJ2B@201174|Actinobacteria,4F4K9@85017|Promicromonosporaceae	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,TusA
SRR25158535_k127_469233_6	58123.JOFJ01000001_gene3185	6.369e-15	82.0	COG0425@1|root,COG0425@2|Bacteria,2GSF4@201174|Actinobacteria,4EK4Z@85012|Streptosporangiales	201174|Actinobacteria	O	Sulfurtransferase TusA	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
SRR25158535_k127_469233_3	1463864.JOGO01000003_gene1876	1.227e-49	179.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the HesB IscA family	iscA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SRR25158535_k127_469233_4	1463841.JOIR01000002_gene6087	3.555e-45	170.0	COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria	201174|Actinobacteria	S	YbaK prolyl-tRNA synthetase associated region	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
SRR25158535_k127_469233_1	469371.Tbis_2591	8.216e-121	402.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4DXZB@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
SRR25158535_k127_469233_0	525909.Afer_1427	1.163e-149	492.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_469233_7	1210046.B277_08639	2.528e-09	69.0	2DMQ5@1|root,32SZ1@2|Bacteria,2I3N2@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
SRR25158535_k127_469233_2	33876.JNXY01000045_gene1937	1.482e-59	207.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DC6D@85008|Micromonosporales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	fdhA	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,AlaDh_PNT_C
SRR25158535_k127_474748_0	593907.Celgi_1587	5.189e-287	901.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4F0M3@85016|Cellulomonadaceae	201174|Actinobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SRR25158535_k127_490850_8	1032480.MLP_14740	4.507e-10	72.0	COG0769@1|root,COG0769@2|Bacteria,2GME3@201174|Actinobacteria,4DPYG@85009|Propionibacteriales	201174|Actinobacteria	M	Mur ligase middle domain	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,TPR_5
SRR25158535_k127_490850_1	479434.Sthe_3421	1.82e-112	374.0	COG1052@1|root,COG1052@2|Bacteria,2G6NV@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	-	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158535_k127_490850_2	1896.JOAU01000026_gene3337	8.303e-108	365.0	COG0624@1|root,COG0624@2|Bacteria,2GMH2@201174|Actinobacteria	201174|Actinobacteria	E	peptidase	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SRR25158535_k127_490850_5	656024.FsymDg_0692	5.098e-82	286.0	COG0392@1|root,COG0392@2|Bacteria,2GZ8W@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	2.3.2.3	ko:K07027,ko:K14205,ko:K20468	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SRR25158535_k127_490850_3	1122611.KB903974_gene2885	7.816e-90	304.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,4EHIV@85012|Streptosporangiales	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SRR25158535_k127_490850_0	443218.AS9A_4180	2.083e-134	460.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,232ZK@1762|Mycobacteriaceae	201174|Actinobacteria	L	DNA ligase	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SRR25158535_k127_490850_4	1382306.JNIM01000001_gene732	6.812e-86	292.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_490850_6	370438.PTH_0451	2.871e-65	243.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,260PU@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_490850_7	929712.KI912613_gene1735	1.161e-12	73.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CS29@84995|Rubrobacteria	84995|Rubrobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SRR25158535_k127_512118_7	1246995.AFR_07830	2.81e-07	64.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4D8JA@85008|Micromonosporales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158535_k127_512118_0	1033730.CAHG01000016_gene185	4.369e-269	841.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4DNM0@85009|Propionibacteriales	201174|Actinobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
SRR25158535_k127_512118_6	1123065.ATWL01000007_gene3264	3.239e-25	107.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SRR25158535_k127_512118_5	479432.Sros_2278	9.048e-29	128.0	COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4EHWU@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
SRR25158535_k127_512118_3	266117.Rxyl_2098	1.711e-78	279.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4CQ65@84995|Rubrobacteria	84995|Rubrobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_512118_1	42256.RradSPS_1883	4.785e-86	297.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CSXQ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
SRR25158535_k127_512118_2	909613.UO65_6451	7.926e-79	284.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria,4E3U9@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_512118_4	105420.BBPO01000045_gene1052	3.745e-68	236.0	COG2318@1|root,COG2318@2|Bacteria,2II7R@201174|Actinobacteria,2NHEG@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
SRR25158535_k127_512118_8	446462.Amir_1203	4.284e-06	53.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4DXGV@85010|Pseudonocardiales	201174|Actinobacteria	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158535_k127_513011_0	436229.JOEH01000040_gene6437	2.876e-69	254.0	COG0642@1|root,COG2205@2|Bacteria,2GMB9@201174|Actinobacteria,2NFV4@228398|Streptacidiphilus	201174|Actinobacteria	T	PAS fold	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
SRR25158535_k127_513011_2	471852.Tcur_2142	3.691e-58	212.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4EH5S@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SRR25158535_k127_513011_3	1179773.BN6_66130	7.405e-45	166.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4E3EP@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SRR25158535_k127_513011_4	266117.Rxyl_1302	7.431e-10	61.0	COG0291@1|root,COG0291@2|Bacteria,2HPDV@201174|Actinobacteria,4CQRX@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SRR25158535_k127_513011_1	479431.Namu_4144	3.483e-63	233.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4ESDW@85013|Frankiales	201174|Actinobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
SRR25158535_k127_513011_5	1380390.JIAT01000016_gene5505	8.375e-09	62.0	2AUTP@1|root,31KGR@2|Bacteria,2HPBN@201174|Actinobacteria,4CQQ3@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_513011_6	94624.Bpet4978	3.978e-08	54.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,3T4J0@506|Alcaligenaceae	28216|Betaproteobacteria	K	Cold shock	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
SRR25158535_k127_513559_0	1289387.AUKW01000005_gene1900	3.756e-44	170.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria	201174|Actinobacteria	K	GnaT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_513559_1	675635.Psed_3626	9.363e-32	133.0	COG3467@1|root,COG3467@2|Bacteria,2IQIK@201174|Actinobacteria,4E5TC@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_514040_1	479432.Sros_7495	2.383e-33	133.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria,4EGJZ@85012|Streptosporangiales	201174|Actinobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SRR25158535_k127_514040_2	1463887.KL589967_gene6543	4.091e-22	105.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria	201174|Actinobacteria	K	AsnC family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158535_k127_514040_0	1288494.EBAPG3_15610	4.068e-41	158.0	COG1504@1|root,COG1504@2|Bacteria,1RGJ6@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
SRR25158535_k127_514040_4	319003.Bra1253DRAFT_07106	8.684e-11	67.0	28ZQR@1|root,2ZMFP@2|Bacteria,1RBVS@1224|Proteobacteria,2U5S5@28211|Alphaproteobacteria,3JYCN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_516434_3	526225.Gobs_2584	2.534e-40	161.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158535_k127_516434_1	1380390.JIAT01000009_gene2268	6.949e-51	186.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158535_k127_516434_2	134676.ACPL_1738	3.077e-49	186.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria,4DA6N@85008|Micromonosporales	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_516434_0	644283.Micau_4495	3.182e-150	494.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,4D9AC@85008|Micromonosporales	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SRR25158535_k127_516434_4	351607.Acel_0102	1.052e-27	115.0	COG4842@1|root,COG4842@2|Bacteria,2HU2S@201174|Actinobacteria,4EWPE@85013|Frankiales	201174|Actinobacteria	S	PE family	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
SRR25158535_k127_527640_0	1137268.AZXF01000012_gene3599	1.391e-130	439.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4EG9M@85012|Streptosporangiales	201174|Actinobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
SRR25158535_k127_527640_1	1108045.GORHZ_073_00110	1.316e-13	74.0	COG1396@1|root,COG1396@2|Bacteria,2I5G5@201174|Actinobacteria	201174|Actinobacteria	K	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SRR25158535_k127_528321_0	345341.KUTG_00490	2.5e-100	346.0	COG5607@1|root,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4EAUR@85010|Pseudonocardiales	201174|Actinobacteria	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
SRR25158535_k127_528321_1	196162.Noca_2929	5.749e-23	102.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria,4DSMF@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SRR25158535_k127_530320_4	180281.CPCC7001_1381	2.409e-05	48.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,22SQR@167375|Cyanobium	1117|Cyanobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
SRR25158535_k127_530320_0	1463926.JOCA01000025_gene6923	7.267e-118	398.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	nirK	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,Cytochrom_C,Cytochrome_CBB3
SRR25158535_k127_530320_2	1125971.ASJB01000064_gene6508	6.476e-49	187.0	COG4635@1|root,COG4635@2|Bacteria,2IMZZ@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158535_k127_530320_3	1322246.BN4_12019	1.749e-17	89.0	COG0589@1|root,COG0589@2|Bacteria,1PDTQ@1224|Proteobacteria,42T4W@68525|delta/epsilon subdivisions,2WP70@28221|Deltaproteobacteria,2MCM7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SRR25158535_k127_530320_1	67267.JNXT01000011_gene968	1.907e-75	267.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
SRR25158535_k127_531461_6	1246448.ANAZ01000019_gene969	9.922e-13	68.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158535_k127_531461_0	1038859.AXAU01000016_gene6869	1.046e-185	587.0	COG0654@1|root,COG0654@2|Bacteria,1QWT3@1224|Proteobacteria,2U2GE@28211|Alphaproteobacteria,3JZXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SRR25158535_k127_531461_2	1380393.JHVP01000001_gene2518	1.068e-63	246.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,2IASU@201174|Actinobacteria,4EX9U@85013|Frankiales	201174|Actinobacteria	IT	Adenylyl- / guanylyl cyclase, catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
SRR25158535_k127_531461_3	469371.Tbis_0386	5.538e-44	184.0	COG3629@1|root,COG3629@2|Bacteria,2GWP7@201174|Actinobacteria,4DYZX@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,NB-ARC,Trans_reg_C
SRR25158535_k127_531461_1	644283.Micau_1147	1.731e-87	301.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria,4D8JZ@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	kmo	-	1.14.13.113	ko:K16839	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R09514	RC02551	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3,NAD_binding_8
SRR25158535_k127_531461_4	285514.JNWO01000020_gene785	1.108e-34	150.0	COG3279@1|root,COG3279@2|Bacteria,2IR2U@201174|Actinobacteria	201174|Actinobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SRR25158535_k127_531461_5	1283299.AUKG01000001_gene2767	8.305e-16	89.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria,4CSR4@84995|Rubrobacteria	84995|Rubrobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158535_k127_531461_7	1118055.CAGU01000046_gene1733	9.357e-06	57.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,22GV4@1570339|Peptoniphilaceae	186801|Clostridia	P	Chromate transport protein	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_531461_8	1341151.ASZU01000003_gene2597	5.329e-05	50.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4HJZM@91061|Bacilli	91061|Bacilli	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SRR25158535_k127_532555_0	745776.DGo_PC0065	1.145e-147	481.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_537700_3	1380356.JNIK01000016_gene3716	2.478e-41	171.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,4ET12@85013|Frankiales	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
SRR25158535_k127_537700_1	543632.JOJL01000018_gene9073	7.093e-60	228.0	28HWT@1|root,2Z82P@2|Bacteria,2IJH8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_537700_2	349741.Amuc_0414	3.911e-43	172.0	COG0279@1|root,COG0279@2|Bacteria,46SXU@74201|Verrucomicrobia,2IUZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SRR25158535_k127_537700_0	1304866.K413DRAFT_0303	8.161e-68	248.0	COG2605@1|root,COG2605@2|Bacteria,1VU5A@1239|Firmicutes,24BK8@186801|Clostridia,36HT9@31979|Clostridiaceae	186801|Clostridia	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SRR25158535_k127_537700_4	65497.JODV01000003_gene4550	2.599e-40	152.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DXM8@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	pimB	GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_542695_0	1095767.CAHD01000214_gene658	7.369e-89	299.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,4F0FT@85016|Cellulomonadaceae	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158535_k127_542695_1	710111.FraQA3DRAFT_0839	5.327e-73	252.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,4ES3P@85013|Frankiales	201174|Actinobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
SRR25158535_k127_542695_2	469383.Cwoe_3118	1.756e-09	71.0	COG2856@1|root,COG2856@2|Bacteria,2GPBB@201174|Actinobacteria,4CTBZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_547961_1	646529.Desaci_1214	2.769e-83	285.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,260XG@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SRR25158535_k127_547961_0	675635.Psed_0114	4.585e-91	317.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_547961_2	366602.Caul_1373	1.209e-49	197.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2TR5R@28211|Alphaproteobacteria,2KG5S@204458|Caulobacterales	204458|Caulobacterales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SRR25158535_k127_547961_5	146922.JOFU01000017_gene3642	2.965e-26	127.0	COG0784@1|root,COG0784@2|Bacteria,2IT5A@201174|Actinobacteria	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TIR_2
SRR25158535_k127_547961_4	694431.DESACE_08930	3.295e-39	153.0	2E7HQ@1|root,33207@2|Bacteria,1NCYR@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
SRR25158535_k127_547961_3	1907.SGLAU_25465	1.193e-42	168.0	COG0604@1|root,COG0604@2|Bacteria,2I8KK@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
SRR25158535_k127_547980_3	109760.SPPG_00373T0	9.479e-14	77.0	2BSCV@1|root,2S1YD@2759|Eukaryota,39KTS@33154|Opisthokonta,3Q570@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_547980_2	1123270.ATUR01000010_gene1903	8.471e-18	93.0	2EA9M@1|root,334E1@2|Bacteria,1ND0N@1224|Proteobacteria,2UIJ1@28211|Alphaproteobacteria,2K8CC@204457|Sphingomonadales	204457|Sphingomonadales	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
SRR25158535_k127_547980_0	1394178.AWOO02000098_gene8149	8.578e-148	486.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SRR25158535_k127_547980_1	345341.KUTG_07933	4.791e-90	314.0	2E8I5@1|root,332W5@2|Bacteria,2GRF8@201174|Actinobacteria,4E68Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_548622_4	653045.Strvi_4422	2.294e-09	58.0	COG3976@1|root,COG3976@2|Bacteria,2IQDP@201174|Actinobacteria	201174|Actinobacteria	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_548622_1	862751.SACTE_5499	9.379e-141	452.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria	201174|Actinobacteria	K	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_548622_0	298653.Franean1_4232	1.755e-166	528.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EU12@85013|Frankiales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_548622_3	479432.Sros_3626	1.583e-40	153.0	COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria,4EKGQ@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
SRR25158535_k127_548622_2	1122138.AQUZ01000018_gene7529	7.797e-123	408.0	COG3385@1|root,COG3385@2|Bacteria,2GJUG@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
SRR25158535_k127_551950_2	356851.JOAN01000013_gene5719	1.738e-68	256.0	COG1005@1|root,COG1005@2|Bacteria,2GN3R@201174|Actinobacteria,4DB5M@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH2	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158535_k127_551950_0	1120949.KB903319_gene9743	4.986e-145	470.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4DACF@85008|Micromonosporales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
SRR25158535_k127_551950_3	1394178.AWOO02000003_gene2834	5.733e-43	172.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria,4EIQ6@85012|Streptosporangiales	201174|Actinobacteria	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
SRR25158535_k127_551950_1	67257.JODR01000016_gene4652	8.434e-86	298.0	COG0377@1|root,COG0377@2|Bacteria,2GJP5@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB2	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
SRR25158535_k127_551950_4	682795.AciX8_2290	1.486e-25	122.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF5011,FG-GAP_2,NHL,TIG
SRR25158535_k127_558107_10	1048834.TC41_0964	1.405e-05	48.0	COG2120@1|root,COG2120@2|Bacteria,1TPSJ@1239|Firmicutes,4HJJH@91061|Bacilli	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
SRR25158535_k127_558107_3	253839.SSNG_02627	8.682e-105	362.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_558107_7	1229780.BN381_80274	8.814e-38	149.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SRR25158535_k127_558107_5	1123024.AUII01000010_gene784	1.005e-80	277.0	COG2229@1|root,COG2229@2|Bacteria,2GM4V@201174|Actinobacteria	201174|Actinobacteria	S	ATP- GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
SRR25158535_k127_558107_8	2074.JNYD01000012_gene439	1.451e-30	138.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	2.7.1.83	ko:K16328	ko00240,map00240	-	R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF3489,DUF742
SRR25158535_k127_558107_6	1123024.AUII01000010_gene786	1.647e-39	151.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria,4E2K7@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Roadblock LC7	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SRR25158535_k127_558107_1	1123024.AUII01000010_gene787	8.696e-175	570.0	COG0840@1|root,COG4251@1|root,COG0840@2|Bacteria,COG4251@2|Bacteria,2GK6E@201174|Actinobacteria,4DX42@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	cvnA6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
SRR25158535_k127_558107_9	685727.REQ_12380	4.569e-07	63.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4FYY1@85025|Nocardiaceae	201174|Actinobacteria	C	4Fe-4S binding domain	hybA	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7
SRR25158535_k127_558107_0	298655.KI912266_gene1000	1.84e-177	589.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4EUA5@85013|Frankiales	201174|Actinobacteria	EGP	drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_558107_2	1048339.KB913029_gene4807	7.888e-105	360.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4ERI5@85013|Frankiales	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SRR25158535_k127_558107_4	477641.MODMU_1759	9.782e-87	298.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4ERW7@85013|Frankiales	201174|Actinobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA
SRR25158535_k127_560696_0	266117.Rxyl_2824	7.218e-243	765.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA1	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SRR25158535_k127_560696_1	1267535.KB906767_gene561	1.933e-09	68.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
SRR25158535_k127_561809_1	298655.KI912266_gene6192	3.805e-30	124.0	COG0738@1|root,COG0738@2|Bacteria,2HF27@201174|Actinobacteria	201174|Actinobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_561809_0	105422.BBPM01000034_gene1241	6.726e-56	206.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,2NGYF@228398|Streptacidiphilus	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_561809_2	67257.JODR01000012_gene6058	1.449e-07	55.0	COG1414@1|root,COG1414@2|Bacteria,2GP2W@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158535_k127_564507_2	222534.KB893718_gene2205	1.174e-79	291.0	COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,4ESSB@85013|Frankiales	201174|Actinobacteria	P	polar amino acid ABC transporter, inner membrane subunit	gluD	-	-	ko:K10007	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	BPD_transp_1
SRR25158535_k127_564507_3	1120950.KB892756_gene6700	1.536e-79	271.0	COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4DR1N@85009|Propionibacteriales	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	gluC	-	-	ko:K10006,ko:K10040	ko02010,map02010	M00228,M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.9	-	-	BPD_transp_1
SRR25158535_k127_564507_0	326424.FRAAL5714	1.342e-116	385.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4ESNV@85013|Frankiales	201174|Actinobacteria	ET	PFAM Extracellular solute-binding protein, family 3	gluB	-	-	ko:K10005	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.9	-	-	SBP_bac_3
SRR25158535_k127_564507_1	1048339.KB913029_gene3609	1.371e-116	385.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4ES6N@85013|Frankiales	201174|Actinobacteria	E	PFAM ABC transporter	gluA	-	-	ko:K10008	ko02010,map02010	M00233	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.9	-	-	ABC_tran
SRR25158535_k127_564507_5	1957.JODX01000018_gene1755	3.749e-05	48.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SRR25158535_k127_564507_4	68260.JOAY01000001_gene3638	2.085e-17	83.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SRR25158535_k127_565280_5	446462.Amir_1738	1.996e-67	233.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4DZYI@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep,Hexapep_2,PP-binding
SRR25158535_k127_565280_6	1394178.AWOO02000078_gene2013	7.094e-54	198.0	2AZDP@1|root,31RMA@2|Bacteria,2GUFH@201174|Actinobacteria,4EHPR@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
SRR25158535_k127_565280_8	1003195.SCAT_3276	8.966e-14	84.0	2B3QD@1|root,31WDY@2|Bacteria,2GX3A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_565280_4	644283.Micau_1726	5.078e-81	273.0	COG0346@1|root,COG0346@2|Bacteria,2IK75@201174|Actinobacteria,4DD54@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SRR25158535_k127_565280_2	882083.SacmaDRAFT_5380	1.523e-156	538.0	COG1960@1|root,COG1960@2|Bacteria,2GNFB@201174|Actinobacteria,4DY21@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SRR25158535_k127_565280_0	326424.FRAAL1670	1.338e-229	724.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
SRR25158535_k127_565280_3	882083.SacmaDRAFT_5371	1.864e-93	314.0	COG1024@1|root,COG1024@2|Bacteria,2I97K@201174|Actinobacteria,4E2DI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158535_k127_565280_1	350054.Mflv_4614	1.306e-204	663.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,23761@1762|Mycobacteriaceae	201174|Actinobacteria	I	Biotin carboxylase	-	-	6.4.1.1,6.4.1.4	ko:K01959,ko:K01968	ko00020,ko00280,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00280,map00620,map00720,map01100,map01120,map01200,map01230	M00036,M00173,M00620	R00344,R04138	RC00040,RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
SRR25158535_k127_565280_7	446462.Amir_1712	3.942e-52	186.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4DZ29@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD2	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
SRR25158535_k127_568324_3	1172179.AUKV01000028_gene7879	5.113e-105	354.0	COG0477@1|root,COG2814@2|Bacteria,2HCHA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
SRR25158535_k127_568324_2	1463920.JOGB01000022_gene4430	4.747e-107	357.0	COG0640@1|root,COG0640@2|Bacteria,2GPH2@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158535_k127_568324_1	351607.Acel_1371	1.525e-123	408.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria,4ESD3@85013|Frankiales	201174|Actinobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	lppS	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0019538,GO:0030203,GO:0030312,GO:0042546,GO:0043170,GO:0044085,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	YkuD
SRR25158535_k127_568324_0	290397.Adeh_3892	0.0	1065.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2YUEP@29|Myxococcales	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
SRR25158535_k127_568324_5	1304885.AUEY01000113_gene2912	2.964e-20	106.0	COG2931@1|root,COG3210@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,42Q0T@68525|delta/epsilon subdivisions,2WM1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
SRR25158535_k127_568324_4	1347368.HG964405_gene6101	2.605e-22	113.0	COG3391@1|root,COG4632@1|root,COG4733@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	tagL	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Flg_new,NAGPA,SLH
SRR25158535_k127_577088_0	710687.KI912270_gene4527	3.982e-138	457.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria,23FHB@1762|Mycobacteriaceae	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_577088_2	1122138.AQUZ01000056_gene6929	9.423e-113	367.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4DPH5@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_577088_3	1146883.BLASA_3330	7.259e-08	53.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158535_k127_584464_0	1123322.KB904635_gene2476	2.802e-118	394.0	COG2239@1|root,COG2239@2|Bacteria,2GMMK@201174|Actinobacteria	201174|Actinobacteria	P	transporter mgtE	mgtE	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
SRR25158535_k127_584464_1	479431.Namu_2786	7.404e-32	125.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4ERV9@85013|Frankiales	201174|Actinobacteria	E	Vitamin B12 dependent methionine synthase activation	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SRR25158535_k127_630152_2	1122217.KB899572_gene1158	4.112e-15	77.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4H2A2@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SRR25158535_k127_630152_0	429009.Adeg_0957	5.386e-59	220.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,42EZH@68295|Thermoanaerobacterales	186801|Clostridia	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SRR25158535_k127_630152_3	1240349.ANGC01000023_gene3679	1.411e-07	64.0	COG4963@1|root,COG4963@2|Bacteria,2I2PT@201174|Actinobacteria,4FUVK@85025|Nocardiaceae	201174|Actinobacteria	U	Pilus assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_630152_1	1210045.ALNP01000011_gene994	6.043e-30	127.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system protein e	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158535_k127_635219_1	1869.MB27_40360	5.641e-98	330.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DADZ@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
SRR25158535_k127_635219_4	1205680.CAKO01000002_gene2623	5.55e-32	132.0	28K4W@1|root,2Z9TP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_635219_2	525909.Afer_1266	4.147e-80	286.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SRR25158535_k127_635219_3	675635.Psed_4479	2.973e-69	243.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4DYII@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SRR25158535_k127_635219_0	656024.FsymDg_2934	7.256e-140	466.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria,4ETZI@85013|Frankiales	201174|Actinobacteria	S	ATPase component of ABC transporters with duplicated ATPase domain	yjjK	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SRR25158535_k127_635219_6	1123024.AUII01000006_gene4593	1.371e-15	77.0	29X2J@1|root,30IR2@2|Bacteria	2|Bacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
SRR25158535_k127_635219_5	1146883.BLASA_3330	1.932e-22	101.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
SRR25158535_k127_639066_0	33876.JNXY01000042_gene3809	9.146e-86	301.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DBFV@85008|Micromonosporales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SRR25158535_k127_639066_1	33876.JNXY01000042_gene3810	1.133e-78	282.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4D8XT@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_639066_2	1464048.JNZS01000005_gene5420	1.896e-40	160.0	COG0845@1|root,COG0845@2|Bacteria,2I8EY@201174|Actinobacteria,4D93H@85008|Micromonosporales	201174|Actinobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SRR25158535_k127_641011_6	367299.JOEE01000002_gene2532	9.618e-24	102.0	COG1694@1|root,COG1694@2|Bacteria,2ISAF@201174|Actinobacteria,4FJCG@85021|Intrasporangiaceae	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
SRR25158535_k127_641011_1	1288083.AUKR01000002_gene4378	1.198e-106	378.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SRR25158535_k127_641011_5	471852.Tcur_3426	5.122e-39	165.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4EJDG@85012|Streptosporangiales	201174|Actinobacteria	E	Nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SRR25158535_k127_641011_0	880072.Desac_0006	2.191e-141	494.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2MRAX@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SRR25158535_k127_641011_4	1297742.A176_05398	8.722e-45	178.0	COG4552@1|root,COG4552@2|Bacteria,1NBTH@1224|Proteobacteria,42W5G@68525|delta/epsilon subdivisions,2WXK2@28221|Deltaproteobacteria,2YW0Z@29|Myxococcales	28221|Deltaproteobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SRR25158535_k127_641011_3	1122182.KB903835_gene4473	4.772e-89	318.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4D8RT@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158535_k127_641011_2	1121877.JQKF01000011_gene381	3.393e-106	352.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CMX1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	ask	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
SRR25158535_k127_642210_10	1123024.AUII01000015_gene3719	1.864e-16	82.0	COG2072@1|root,COG2072@2|Bacteria,2GM3S@201174|Actinobacteria,4E20H@85010|Pseudonocardiales	201174|Actinobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158535_k127_642210_6	570952.ATVH01000014_gene2068	2.531e-75	264.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_642210_9	661478.OP10G_0294	1.504e-27	128.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
SRR25158535_k127_642210_5	436229.JOEH01000006_gene2920	1.748e-78	284.0	COG0010@1|root,COG0010@2|Bacteria,2HG79@201174|Actinobacteria,2NKGG@228398|Streptacidiphilus	201174|Actinobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
SRR25158535_k127_642210_8	1280390.CBQR020000050_gene1021	1.768e-34	147.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,26SQY@186822|Paenibacillaceae	91061|Bacilli	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
SRR25158535_k127_642210_4	471852.Tcur_2120	3.696e-89	299.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,4EHV3@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
SRR25158535_k127_642210_2	477641.MODMU_3348	1.779e-121	414.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4ET9J@85013|Frankiales	201174|Actinobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SRR25158535_k127_642210_0	471852.Tcur_2128	9.775e-189	620.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4EFGR@85012|Streptosporangiales	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SRR25158535_k127_642210_1	867903.ThesuDRAFT_00011	2.274e-145	480.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WCQW@538999|Clostridiales incertae sedis	186801|Clostridia	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SRR25158535_k127_642210_7	485913.Krac_5347	3.396e-37	143.0	COG5207@1|root,COG5207@2|Bacteria	2|Bacteria	O	Pfam Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
SRR25158535_k127_642210_3	1380390.JIAT01000009_gene2065	7.893e-110	376.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CRC3@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_642210_11	1120950.KB892708_gene4294	2.869e-12	72.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4DS6Z@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
SRR25158535_k127_643313_2	345341.KUTG_09491	1.446e-59	211.0	COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria,4E4DW@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SRR25158535_k127_643313_4	419947.MRA_2585	3.315e-49	178.0	COG0432@1|root,COG0432@2|Bacteria,2IHWS@201174|Actinobacteria,2398U@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterised protein family UPF0047	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	UPF0047
SRR25158535_k127_643313_1	452863.Achl_0089	9.299e-106	353.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,1W8SN@1268|Micrococcaceae	201174|Actinobacteria	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SRR25158535_k127_643313_0	1313172.YM304_06050	2.515e-159	517.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4CMTT@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Fumarate hydratase class II	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SRR25158535_k127_643313_3	298653.Franean1_0323	7.166e-53	201.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4EREG@85013|Frankiales	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
SRR25158535_k127_64435_3	472759.Nhal_0193	7.407e-14	75.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1WXFQ@135613|Chromatiales	135613|Chromatiales	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
SRR25158535_k127_64435_0	1089553.Tph_c01370	4.865e-112	381.0	COG1349@1|root,COG1349@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1670,DeoRC,HTH_DeoR
SRR25158535_k127_64435_1	1089553.Tph_c01380	8.52e-69	252.0	COG1349@1|root,COG1349@2|Bacteria,1VC1B@1239|Firmicutes,24P9E@186801|Clostridia	186801|Clostridia	GK	Protein of unknown function (DUF1670)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1670
SRR25158535_k127_646545_1	543632.JOJL01000016_gene8774	8.515e-41	152.0	COG3547@1|root,COG3547@2|Bacteria,2H56K@201174|Actinobacteria	201174|Actinobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_646545_0	543632.JOJL01000128_gene6516	1.992e-144	473.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4DB2V@85008|Micromonosporales	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_648446_5	330214.NIDE3110	1.502e-23	102.0	COG3508@1|root,COG3508@2|Bacteria	2|Bacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
SRR25158535_k127_648446_0	525909.Afer_1427	4.666e-142	481.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_648446_4	749927.AMED_3537	1.877e-43	166.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_648446_6	1121451.DESAM_21691	1.868e-05	49.0	COG2104@1|root,COG2104@2|Bacteria,1P6X4@1224|Proteobacteria,4323S@68525|delta/epsilon subdivisions,2WXT2@28221|Deltaproteobacteria,2ME0H@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	thiamine diphosphate biosynthetic process	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	-
SRR25158535_k127_648446_1	867903.ThesuDRAFT_00793	2.1e-97	329.0	COG0037@1|root,COG0037@2|Bacteria,1UB13@1239|Firmicutes,249NH@186801|Clostridia	186801|Clostridia	H	Belongs to the TtcA family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
SRR25158535_k127_648446_2	1240349.ANGC01000044_gene4508	7.566e-74	270.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4FUZ9@85025|Nocardiaceae	201174|Actinobacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
SRR25158535_k127_648446_3	471852.Tcur_2307	3.531e-67	235.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4EHNZ@85012|Streptosporangiales	201174|Actinobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis	arc	GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
SRR25158535_k127_649534_1	33876.JNXY01000049_gene2360	2.604e-173	559.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4D90U@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SRR25158535_k127_649534_4	512565.AMIS_61170	2.407e-105	347.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria,4D9FI@85008|Micromonosporales	201174|Actinobacteria	K	DeoR C terminal sensor domain	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
SRR25158535_k127_649534_3	436229.JOEH01000015_gene5947	7.758e-109	380.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,2NIC2@228398|Streptacidiphilus	201174|Actinobacteria	G	pfkB family carbohydrate kinase	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158535_k127_649534_5	105422.BBPM01000001_gene4782	2.707e-68	234.0	COG1762@1|root,COG1762@2|Bacteria,2IMPP@201174|Actinobacteria,2NME4@228398|Streptacidiphilus	201174|Actinobacteria	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	fruB	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
SRR25158535_k127_649534_2	2074.JNYD01000009_gene5170	7.576e-166	542.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,2GJU4@201174|Actinobacteria,4E0S5@85010|Pseudonocardiales	201174|Actinobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
SRR25158535_k127_649534_6	1068978.AMETH_4861	6.366e-26	110.0	COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4E63H@85010|Pseudonocardiales	201174|Actinobacteria	G	TIGRFAM Phosphotransferase System HPr (HPr) Family	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SRR25158535_k127_649534_0	58123.JOFJ01000004_gene1825	3.477e-182	588.0	COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4EGVU@85012|Streptosporangiales	201174|Actinobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
SRR25158535_k127_649534_7	266117.Rxyl_0965	5.605e-24	104.0	297P3@1|root,2ZUW0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_651453_0	298655.KI912266_gene5495	1.122e-153	518.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4ERY4@85013|Frankiales	201174|Actinobacteria	J	ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
SRR25158535_k127_651453_3	561175.KB894104_gene1145	8.626e-100	342.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,4EFT6@85012|Streptosporangiales	201174|Actinobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SRR25158535_k127_651453_2	1048834.TC41_0423	1.044e-114	401.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,4HD8I@91061|Bacilli,2795V@186823|Alicyclobacillaceae	91061|Bacilli	L	Helix-turn-helix domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_651453_1	446468.Ndas_3385	2.478e-132	448.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4EHIA@85012|Streptosporangiales	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	FTSW_RODA_SPOVE,PBP_dimer,Transpeptidase
SRR25158535_k127_651453_5	1206101.AZXC01000001_gene4544	8.444e-17	86.0	COG2891@1|root,COG2891@2|Bacteria,2GN0I@201174|Actinobacteria	201174|Actinobacteria	M	rod shape-determining protein (MreD)	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
SRR25158535_k127_651453_4	1160718.SU9_20574	2.321e-35	148.0	COG1792@1|root,COG1792@2|Bacteria,2GJN0@201174|Actinobacteria	201174|Actinobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SRR25158535_k127_651453_6	656024.FsymDg_1524	1.8e-15	76.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4ES3S@85013|Frankiales	201174|Actinobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SRR25158535_k127_652991_3	345341.KUTG_01433	2.274e-33	151.0	COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4E224@85010|Pseudonocardiales	201174|Actinobacteria	GK	PFAM ROK family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,MarR_2,ROK
SRR25158535_k127_652991_0	1137271.AZUM01000004_gene3981	2.233e-189	602.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4DXQ6@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
SRR25158535_k127_652991_1	208444.JNYY01000003_gene1777	1.624e-168	538.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4DY1G@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SRR25158535_k127_652991_2	1463820.JOGW01000012_gene3810	3.201e-61	231.0	COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SRR25158535_k127_654763_2	1121946.AUAX01000016_gene4760	8.024e-16	86.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
SRR25158535_k127_654763_0	390989.JOEG01000011_gene118	1.251e-148	482.0	COG1541@1|root,COG1541@2|Bacteria,2GJC7@201174|Actinobacteria,4DBRE@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SRR25158535_k127_654763_1	867903.ThesuDRAFT_00093	1.856e-86	302.0	COG0334@1|root,COG0334@2|Bacteria,1TR4Z@1239|Firmicutes,25CDT@186801|Clostridia	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SRR25158535_k127_66368_6	1211815.CBYP010000047_gene1618	6.173e-55	200.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4ESBC@85013|Frankiales	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SRR25158535_k127_66368_3	1192034.CAP_1582	3.645e-63	228.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,43BQ1@68525|delta/epsilon subdivisions,2X718@28221|Deltaproteobacteria,2Z3MK@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SRR25158535_k127_66368_0	1122611.KB903939_gene389	9.168e-131	439.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4EFPH@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
SRR25158535_k127_66368_7	1120950.KB892708_gene4465	9.094e-46	167.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4DRRB@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
SRR25158535_k127_66368_10	479435.Kfla_3563	6.276e-09	66.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4DS2R@85009|Propionibacteriales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_66368_1	1120950.KB892707_gene4841	7.489e-91	310.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4DS2R@85009|Propionibacteriales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SRR25158535_k127_66368_4	1236902.ANAS01000001_gene1837	1.828e-61	228.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4EH22@85012|Streptosporangiales	201174|Actinobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SRR25158535_k127_66368_2	479433.Caci_1099	4.552e-76	274.0	COG1414@1|root,COG1414@2|Bacteria,2IA7H@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
SRR25158535_k127_66368_5	479432.Sros_3047	5.677e-61	222.0	COG1461@1|root,COG1461@2|Bacteria,2HEQ9@201174|Actinobacteria,4EJE3@85012|Streptosporangiales	201174|Actinobacteria	S	Dak2	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
SRR25158535_k127_66368_8	1347392.CCEZ01000009_gene2333	7.849e-38	146.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,36JWA@31979|Clostridiaceae	186801|Clostridia	S	dihydroxyacetone kinase, phosphotransfer subunit	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
SRR25158535_k127_66368_9	1038867.AXAY01000002_gene3808	1.799e-18	85.0	COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
SRR25158535_k127_664115_3	2074.JNYD01000079_gene6301	1.101e-55	198.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria,4E8AR@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_664115_1	345341.KUTG_01170	6.003e-86	292.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E23Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR25158535_k127_664115_0	222534.KB893766_gene2941	1.524e-99	336.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_664115_2	222534.KB893766_gene2941	2.935e-84	306.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SRR25158535_k127_664942_0	1122138.AQUZ01000008_gene3765	1.263e-234	732.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4DTG9@85009|Propionibacteriales	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
SRR25158535_k127_665584_1	1394178.AWOO02000015_gene7019	5.241e-101	338.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria,4EI21@85012|Streptosporangiales	201174|Actinobacteria	S	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP
SRR25158535_k127_665584_0	1463854.JOHT01000017_gene3095	6.496e-262	847.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase, family 38	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SRR25158535_k127_665584_2	35754.JNYJ01000010_gene1652	3.472e-70	253.0	COG1073@1|root,COG1073@2|Bacteria,2IC0U@201174|Actinobacteria,4DDBT@85008|Micromonosporales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
SRR25158535_k127_665584_3	882086.SacxiDRAFT_0177	4.796e-39	147.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria,4E34Z@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158535_k127_668187_5	1459636.NTE_02613	7.752e-30	120.0	COG0262@1|root,arCOG01490@2157|Archaea	2157|Archaea	H	Belongs to the dihydrofolate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_668187_7	928724.SacglDRAFT_02934	7.808e-09	61.0	COG3293@1|root,COG3293@2|Bacteria,2IIAY@201174|Actinobacteria,4E3DP@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
SRR25158535_k127_668187_3	1380393.JHVP01000002_gene1786	1.887e-86	295.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4ERQ0@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
SRR25158535_k127_668187_4	795359.TOPB45_0396	2.384e-67	240.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	metF3	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SRR25158535_k127_668187_2	867903.ThesuDRAFT_01574	3.995e-119	411.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WD3X@538999|Clostridiales incertae sedis	186801|Clostridia	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SRR25158535_k127_668187_0	1303518.CCALI_00259	1.843e-165	547.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SRR25158535_k127_668187_1	298653.Franean1_5970	5.04e-124	427.0	COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4ESBM@85013|Frankiales	201174|Actinobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
SRR25158535_k127_668187_8	208439.AJAP_42630	0.000842	46.0	2BCCD@1|root,325XS@2|Bacteria,2HB8D@201174|Actinobacteria,4EDJ8@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_668187_6	1121013.P873_12755	1.033e-25	117.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1X4CK@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_669283_4	525904.Tter_0413	7.147e-81	289.0	COG0364@1|root,COG0364@2|Bacteria,2NNUR@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SRR25158535_k127_669283_3	926550.CLDAP_03770	2.726e-104	364.0	COG0176@1|root,COG0176@2|Bacteria,2GA93@200795|Chloroflexi	200795|Chloroflexi	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SRR25158535_k127_669283_1	1125863.JAFN01000001_gene1711	5.641e-244	805.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SRR25158535_k127_669283_0	321332.CYB_2082	1.825e-250	792.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1GYE0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
SRR25158535_k127_669283_2	351607.Acel_0683	1.816e-164	527.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria	201174|Actinobacteria	D	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
SRR25158535_k127_670616_0	526225.Gobs_2031	4.303e-152	488.0	COG3547@1|root,COG3547@2|Bacteria,2H56K@201174|Actinobacteria,4EXAV@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_670616_1	1120950.KB892707_gene4732	7.773e-112	364.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4DNMB@85009|Propionibacteriales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2900c	Molybdopterin,Molydop_binding
SRR25158535_k127_676029_5	926560.KE387023_gene3677	2.364e-29	132.0	COG2133@1|root,COG2133@2|Bacteria,1WKVV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_676029_6	671143.DAMO_1984	2.506e-29	125.0	2CTJW@1|root,32STM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_676029_3	449447.MAE_41970	2.477e-73	256.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,HTH_3,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25,Methyltransf_31
SRR25158535_k127_676029_2	1254432.SCE1572_38725	4.8e-87	305.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,43BD6@68525|delta/epsilon subdivisions,2X6S2@28221|Deltaproteobacteria,2Z0N7@29|Myxococcales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_676029_1	469383.Cwoe_3724	1.461e-116	389.0	COG1294@1|root,COG1294@2|Bacteria,2GN42@201174|Actinobacteria,4CRFG@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
SRR25158535_k127_676029_0	469383.Cwoe_3723	2.142e-191	607.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4CRA5@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SRR25158535_k127_676029_4	67281.JNZZ01000002_gene2656	5.639e-55	220.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K02238,ko:K06889	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Hydrolase_4
SRR25158535_k127_676889_0	1380347.JNII01000006_gene1628	5.307e-116	392.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_689655_0	1120949.KB903294_gene3515	1.962e-170	542.0	COG1879@1|root,COG1879@2|Bacteria,2ICHZ@201174|Actinobacteria,4DHED@85008|Micromonosporales	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
SRR25158535_k127_689655_1	1380390.JIAT01000009_gene907	1.395e-151	486.0	COG2017@1|root,COG2017@2|Bacteria,2GME9@201174|Actinobacteria,4CSDF@84995|Rubrobacteria	84995|Rubrobacteria	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
SRR25158535_k127_690912_5	1123320.KB889596_gene8717	6.569e-12	79.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SRR25158535_k127_690912_2	28042.GU90_06205	4.435e-62	240.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4E00W@85010|Pseudonocardiales	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
SRR25158535_k127_690912_0	1121946.AUAX01000008_gene7184	1.56e-179	574.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4D8EK@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SRR25158535_k127_690912_1	1278308.KB907074_gene746	6.186e-97	332.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4FK95@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	GO:0003674,GO:0003824,GO:0004633,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SRR25158535_k127_690912_4	1068978.AMETH_4139	2.032e-16	90.0	COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4E5KY@85010|Pseudonocardiales	201174|Actinobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SRR25158535_k127_690912_3	390989.JOEG01000012_gene3249	4.289e-57	208.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4DA6T@85008|Micromonosporales	201174|Actinobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SRR25158535_k127_690912_6	43354.JOIJ01000006_gene1740	3.965e-06	49.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4E4HM@85010|Pseudonocardiales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_694543_0	1464048.JNZS01000033_gene2824	2.019e-120	400.0	COG0438@1|root,COG0438@2|Bacteria,2IBM0@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SRR25158535_k127_694543_1	356851.JOAN01000016_gene6164	1.526e-78	278.0	29TUY@1|root,30F3F@2|Bacteria	2|Bacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
SRR25158535_k127_694543_3	66373.JOFQ01000003_gene5730	3.807e-17	97.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	stsA	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158535_k127_694543_2	395495.Lcho_2360	1.093e-38	168.0	COG5653@1|root,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,2VXRC@28216|Betaproteobacteria,1KN5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SRR25158535_k127_695489_1	696369.KI912183_gene898	3.841e-71	252.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,260PG@186807|Peptococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SRR25158535_k127_695489_2	1210045.ALNP01000016_gene1925	1.057e-58	223.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
SRR25158535_k127_695489_0	765952.PUV_14140	7.04e-156	512.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2JG49@204428|Chlamydiae	204428|Chlamydiae	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
SRR25158535_k127_695968_0	1380390.JIAT01000010_gene4392	1.127e-169	561.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_695968_1	105425.BBPL01000061_gene5171	2.765e-93	317.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria	201174|Actinobacteria	P	Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SRR25158535_k127_695968_3	345341.KUTG_06832	3.462e-36	147.0	COG0789@1|root,COG0789@2|Bacteria,2GKSZ@201174|Actinobacteria,4E1X0@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158535_k127_695968_2	861299.J421_0680	5.556e-74	255.0	COG2072@1|root,COG2072@2|Bacteria,1ZV84@142182|Gemmatimonadetes	2|Bacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
SRR25158535_k127_696733_2	1116472.MGMO_7c00210	3.692e-38	155.0	COG3211@1|root,COG3211@2|Bacteria,1R7E2@1224|Proteobacteria,1SCSQ@1236|Gammaproteobacteria,1XGF9@135618|Methylococcales	135618|Methylococcales	S	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
SRR25158535_k127_696733_1	103733.JNYO01000014_gene3707	2.611e-140	459.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria,4E0KC@85010|Pseudonocardiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
SRR25158535_k127_696733_0	1463917.JODC01000021_gene9127	1.788e-188	614.0	COG2409@1|root,COG2409@2|Bacteria,2HU5I@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
SRR25158535_k127_696733_3	446470.Snas_4946	4.059e-11	63.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EXYW@85014|Glycomycetales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_697929_1	710111.FraQA3DRAFT_3037	1.322e-63	229.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4ES5C@85013|Frankiales	201174|Actinobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	iNJ661.Rv2388c	HemN_C,Radical_SAM
SRR25158535_k127_697929_3	557598.LHK_03181	3.314e-12	78.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,2KRZB@206351|Neisseriales	206351|Neisseriales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SRR25158535_k127_697929_2	1894.JOER01000101_gene7500	3.736e-49	194.0	COG0491@1|root,COG0491@2|Bacteria,2H8JM@201174|Actinobacteria	201174|Actinobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SRR25158535_k127_697929_4	749927.AMED_0570	2.781e-09	68.0	2DQ4Z@1|root,334SM@2|Bacteria,2GWJC@201174|Actinobacteria,4E7K9@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2568
SRR25158535_k127_697929_0	436229.JOEH01000011_gene5542	1.505e-64	227.0	COG1309@1|root,COG1309@2|Bacteria,2IJTA@201174|Actinobacteria,2NKZ9@228398|Streptacidiphilus	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158535_k127_698372_1	452652.KSE_32865	8.167e-23	103.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158535_k127_698372_0	653045.Strvi_4608	1.71e-157	513.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158535_k127_70738_2	477641.MODMU_4409	4.043e-17	92.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4ETCV@85013|Frankiales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SRR25158535_k127_70738_0	710111.FraQA3DRAFT_1340	5.055e-63	233.0	COG1403@1|root,COG1403@2|Bacteria,2GU7G@201174|Actinobacteria,4EV73@85013|Frankiales	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SRR25158535_k127_70738_1	1449976.KALB_6465	8.3e-53	196.0	COG3324@1|root,COG3324@2|Bacteria,2I4XW@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_708357_2	1056816.JAFQ01000004_gene5563	8.15e-08	54.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria,4G1I2@85025|Nocardiaceae	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
SRR25158535_k127_708357_1	765911.Thivi_1125	9.292e-59	208.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,1T09A@1236|Gammaproteobacteria,1WX5C@135613|Chromatiales	135613|Chromatiales	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	-	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
SRR25158535_k127_708357_0	234267.Acid_5018	2.158e-141	467.0	COG1894@1|root,COG1894@2|Bacteria,3Y6TY@57723|Acidobacteria	57723|Acidobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K05587	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Complex1_51K,NADH_4Fe-4S
SRR25158535_k127_712341_17	1048339.KB913029_gene2205	6.864e-08	53.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4ES9S@85013|Frankiales	201174|Actinobacteria	L	exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SRR25158535_k127_712341_18	471853.Bcav_2715	3.151e-06	52.0	COG0477@1|root,COG2814@2|Bacteria,2I7XA@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_712341_6	1033730.CAHG01000006_gene1202	4.336e-125	431.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4DRHN@85009|Propionibacteriales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
SRR25158535_k127_712341_5	1463825.JNXC01000023_gene4960	4.069e-136	456.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DYYG@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158535_k127_712341_9	585531.HMPREF0063_10396	2.572e-92	314.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DPF0@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
SRR25158535_k127_712341_0	40571.JOEA01000006_gene4405	1.524e-260	836.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DZ2U@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-forming long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SRR25158535_k127_712341_8	935866.JAER01000010_gene4130	2.255e-113	385.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DPBA@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
SRR25158535_k127_712341_10	67332.FM21_31565	3.07e-78	269.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	braG	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
SRR25158535_k127_712341_3	266117.Rxyl_1749	6.708e-172	554.0	COG1012@1|root,COG1012@2|Bacteria,2H1UT@201174|Actinobacteria,4CSB5@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_712341_11	266117.Rxyl_1748	2.81e-72	252.0	COG1024@1|root,COG1024@2|Bacteria,2GNXD@201174|Actinobacteria,4CQCF@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
SRR25158535_k127_712341_13	266117.Rxyl_1747	7.291e-48	179.0	COG1309@1|root,COG1309@2|Bacteria,2HRRV@201174|Actinobacteria,4CTUM@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SRR25158535_k127_712341_1	266117.Rxyl_1760	6.047e-203	648.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CRW6@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SRR25158535_k127_712341_2	266117.Rxyl_1759	3.198e-192	636.0	COG0365@1|root,COG0365@2|Bacteria,2GJVK@201174|Actinobacteria,4CRKB@84995|Rubrobacteria	84995|Rubrobacteria	I	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_712341_7	1394178.AWOO02000044_gene4487	3.412e-120	417.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
SRR25158535_k127_712341_4	266117.Rxyl_1756	1.385e-136	457.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4CQIA@84995|Rubrobacteria	84995|Rubrobacteria	S	phenylacetic acid catabolic	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158535_k127_712341_14	266117.Rxyl_1755	2.948e-22	102.0	COG2151@1|root,COG2151@2|Bacteria,2HPEM@201174|Actinobacteria,4CQST@84995|Rubrobacteria	84995|Rubrobacteria	S	Pfam:DUF59	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
SRR25158535_k127_712341_12	266117.Rxyl_1752	3.194e-65	235.0	COG3396@1|root,COG3396@2|Bacteria,2H8M9@201174|Actinobacteria,4CTNC@84995|Rubrobacteria	84995|Rubrobacteria	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
SRR25158535_k127_71269_3	1304880.JAGB01000005_gene2434	6.702e-141	454.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SRR25158535_k127_71269_0	717605.Theco_3754	7.701e-244	771.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26R74@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SRR25158535_k127_71269_14	1157637.KB892098_gene2112	5.811e-19	90.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria	201174|Actinobacteria	S	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
SRR25158535_k127_71269_4	1306406.ASHX01000001_gene1725	1.648e-104	351.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SRR25158535_k127_71269_8	1313172.YM304_00020	5.317e-77	271.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CN18@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA polymerase III beta subunit	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SRR25158535_k127_71269_1	351607.Acel_0001	4.367e-175	561.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4ES24@85013|Frankiales	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
SRR25158535_k127_71269_16	1906.SFRA_12570	8.635e-14	71.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SRR25158535_k127_71269_15	562970.Btus_3322	1.82e-18	91.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,278N4@186823|Alicyclobacillaceae	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SRR25158535_k127_71269_13	2074.JNYD01000004_gene4862	5.208e-24	111.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SRR25158535_k127_71269_10	1463879.JOHP01000003_gene5656	3.884e-40	162.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria	201174|Actinobacteria	U	Membrane protein insertase, YidC Oxa1 family	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
SRR25158535_k127_71269_12	298653.Franean1_7337	3.384e-34	145.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4ESQX@85013|Frankiales	201174|Actinobacteria	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
SRR25158535_k127_71269_11	585506.HMPREF0877_0566	1.042e-38	155.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,4AX58@81850|Leuconostocaceae	91061|Bacilli	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SRR25158535_k127_71269_5	525909.Afer_2031	1.244e-88	325.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CMSR@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SRR25158535_k127_71269_6	675635.Psed_6685	2.428e-84	304.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4DXY2@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SRR25158535_k127_71269_7	219305.MCAG_02868	6.954e-83	291.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4DA6S@85008|Micromonosporales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SRR25158535_k127_71269_2	479433.Caci_9047	1.241e-158	513.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria	201174|Actinobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	avtA	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SRR25158535_k127_71269_9	994479.GL877880_gene3972	5.095e-55	203.0	COG3153@1|root,COG3153@2|Bacteria,2GNNB@201174|Actinobacteria,4DXW4@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_718121_3	1429046.RR21198_2648	8.379e-15	74.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria,4FZI8@85025|Nocardiaceae	201174|Actinobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
SRR25158535_k127_718121_1	28444.JODQ01000008_gene1181	4.636e-72	254.0	COG0664@1|root,COG0664@2|Bacteria,2I8QQ@201174|Actinobacteria,4EGBT@85012|Streptosporangiales	201174|Actinobacteria	T	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SRR25158535_k127_718121_0	1150864.MILUP08_45186	5.393e-109	392.0	COG1040@1|root,COG2114@1|root,COG3899@1|root,COG1040@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
SRR25158535_k127_718121_2	1045009.AFXQ01000002_gene1561	5.16e-18	91.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,1W7PM@1268|Micrococcaceae	201174|Actinobacteria	G	Fibronectin type III-like domain	bglS	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SRR25158535_k127_718121_5	287986.DV20_42565	0.00013	51.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4DZB8@85010|Pseudonocardiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
SRR25158535_k127_718121_4	1464048.JNZS01000011_gene4961	4.419e-09	62.0	COG0582@1|root,COG2188@1|root,COG0582@2|Bacteria,COG2188@2|Bacteria,2I9QS@201174|Actinobacteria,4DC0Q@85008|Micromonosporales	201174|Actinobacteria	K	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SRR25158535_k127_729197_0	44060.JODL01000068_gene3812	2.909e-111	366.0	COG3039@1|root,COG3039@2|Bacteria,2GJQM@201174|Actinobacteria	201174|Actinobacteria	L	Cluster 0025 8 SCAB3371, SCAB4481, SCAB7601, SCAB11701, SCAB20281, SCAB40511, SCAB68181	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_729197_3	251221.35210711	6.384e-30	121.0	COG3039@1|root,COG3039@2|Bacteria,1G52R@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158535_k127_729197_2	1229780.BN381_210018	7.563e-64	226.0	COG2442@1|root,COG2442@2|Bacteria,2IE5W@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SRR25158535_k127_729197_4	1229780.BN381_210019	1.208e-20	96.0	2CNI4@1|root,32SH5@2|Bacteria,2IJ9Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_729197_1	1043205.AFYF01000051_gene3038	3.16e-69	239.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4FF9T@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG3464 Transposase and inactivated derivatives	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
SRR25158535_k127_737_3	1122611.KB903940_gene1758	6.47e-88	303.0	COG0296@1|root,COG0296@2|Bacteria,2GMIS@201174|Actinobacteria,4EG9E@85012|Streptosporangiales	201174|Actinobacteria	G	Domain of unknown function (DUF3459)	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SRR25158535_k127_737_6	258052.JNYV01000015_gene3086	2.786e-49	193.0	COG1637@1|root,COG1637@2|Bacteria,2ICA9@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	DUF4268
SRR25158535_k127_737_5	66429.JOFL01000003_gene3418	2.468e-54	205.0	COG1296@1|root,COG1296@2|Bacteria,2IJ35@201174|Actinobacteria	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
SRR25158535_k127_737_10	67275.JOAP01000066_gene3785	1.242e-09	72.0	2DT93@1|root,33J8Y@2|Bacteria,2GWPP@201174|Actinobacteria	201174|Actinobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
SRR25158535_k127_737_8	1047013.AQSP01000138_gene1074	1.562e-31	128.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	mazF5	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SRR25158535_k127_737_4	298654.FraEuI1c_1954	5.407e-74	266.0	COG1946@1|root,COG1946@2|Bacteria,2GMZB@201174|Actinobacteria,4ET11@85013|Frankiales	201174|Actinobacteria	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
SRR25158535_k127_737_2	326427.Cagg_0348	4.393e-152	493.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
SRR25158535_k127_737_0	42256.RradSPS_1839	3.067e-320	1001.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2IBPW@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SRR25158535_k127_737_1	1121946.AUAX01000002_gene33	1.013e-161	527.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DAEW@85008|Micromonosporales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_737_9	485913.Krac_8476	7.163e-21	98.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
SRR25158535_k127_737_7	469383.Cwoe_0532	1.369e-45	171.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,4CQD0@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_737457_4	1122138.AQUZ01000025_gene2804	5.318e-44	170.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
SRR25158535_k127_737457_2	1382356.JQMP01000003_gene1582	1.187e-129	434.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,27XX7@189775|Thermomicrobia	189775|Thermomicrobia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SRR25158535_k127_737457_5	1278073.MYSTI_07100	6.554e-34	136.0	COG1846@1|root,COG1846@2|Bacteria,1NKV4@1224|Proteobacteria,42RNI@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SRR25158535_k127_737457_8	219305.MCAG_04221	1.131e-21	100.0	COG0776@1|root,COG0776@2|Bacteria,2GV0M@201174|Actinobacteria,4DDIV@85008|Micromonosporales	201174|Actinobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SRR25158535_k127_737457_9	1380346.JNIH01000008_gene1451	2.641e-07	62.0	COG1920@1|root,COG1920@2|Bacteria,2GQPF@201174|Actinobacteria	201174|Actinobacteria	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_737457_7	1292020.H483_0107645	5.952e-23	113.0	COG1920@1|root,COG1920@2|Bacteria,2HJNU@201174|Actinobacteria	201174|Actinobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
SRR25158535_k127_737457_3	1123320.KB889676_gene2895	3.85e-47	188.0	COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SRR25158535_k127_737457_1	1894.JOER01000017_gene4770	5.971e-130	426.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	megL	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SRR25158535_k127_737457_6	926554.KI912671_gene194	1.761e-28	133.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SRR25158535_k127_737457_0	1122138.AQUZ01000001_gene1795	2.473e-133	435.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DSSQ@85009|Propionibacteriales	201174|Actinobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8,fn3_5
SRR25158535_k127_753821_0	479435.Kfla_4559	1.795e-79	276.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DN0C@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_753821_2	479434.Sthe_2964	2.65e-48	186.0	2DMIC@1|root,32RRV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
SRR25158535_k127_753821_1	1996.JOFO01000025_gene4356	9.281e-57	204.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4EG6G@85012|Streptosporangiales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_primase_S
SRR25158535_k127_763443_0	1166948.JPZL01000004_gene171	1.561e-122	400.0	COG1024@1|root,COG1024@2|Bacteria,1Q51H@1224|Proteobacteria,1S2T1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_763443_2	882082.SaccyDRAFT_0025	1.277e-69	248.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria,4DYIC@85010|Pseudonocardiales	201174|Actinobacteria	O	Sucrase/ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
SRR25158535_k127_763443_1	882082.SaccyDRAFT_0024	2.249e-97	335.0	COG2850@1|root,COG2850@2|Bacteria,2GMR2@201174|Actinobacteria,4DYRP@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
SRR25158535_k127_763443_3	479432.Sros_1267	3.374e-44	165.0	COG0026@1|root,COG0026@2|Bacteria,2I3IE@201174|Actinobacteria,4EK7B@85012|Streptosporangiales	201174|Actinobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SRR25158535_k127_764239_2	1380356.JNIK01000018_gene821	2.693e-06	57.0	COG0392@1|root,COG0392@2|Bacteria,2ICMJ@201174|Actinobacteria,4ETKK@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SRR25158535_k127_764239_0	1380393.JHVP01000004_gene396	4.025e-79	289.0	COG4425@1|root,COG4425@2|Bacteria,2IBWT@201174|Actinobacteria,4ETTC@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta-hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_9,Abhydrolase_9_N
SRR25158535_k127_764239_1	2002.JOEQ01000010_gene6264	1.143e-25	117.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria,4EJD8@85012|Streptosporangiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SRR25158535_k127_764239_3	1380390.JIAT01000009_gene669	7.061e-06	56.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4CTKF@84995|Rubrobacteria	84995|Rubrobacteria	L	TrwC relaxase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,TrwC
SRR25158535_k127_774198_0	1137271.AZUM01000010_gene1740	1.094e-46	185.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4DYK7@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SRR25158535_k127_774198_1	1380390.JIAT01000009_gene711	1.441e-36	148.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4CQR5@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
SRR25158535_k127_780586_5	1304865.JAGF01000001_gene399	9.005e-17	81.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4F0QK@85016|Cellulomonadaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SRR25158535_k127_780586_4	219305.MCAG_02723	2.892e-54	211.0	COG5002@1|root,COG5002@2|Bacteria,2GMH4@201174|Actinobacteria,4DAGR@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	baeS	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_780586_1	1122182.KB903838_gene4184	3.076e-103	350.0	COG0842@1|root,COG0842@2|Bacteria,2GP9E@201174|Actinobacteria,4DCXD@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
SRR25158535_k127_780586_0	33876.JNXY01000010_gene2499	1.327e-126	415.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DC7R@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_780586_3	367299.JOEE01000005_gene3510	3.611e-55	218.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4FFW9@85021|Intrasporangiaceae	201174|Actinobacteria	E	Belongs to the TrpC family	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
SRR25158535_k127_780586_2	1382356.JQMP01000001_gene1155	1.25e-102	345.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi,27XSD@189775|Thermomicrobia	189775|Thermomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SRR25158535_k127_783761_2	471852.Tcur_3266	1.831e-36	158.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2GJGR@201174|Actinobacteria,4EGU5@85012|Streptosporangiales	201174|Actinobacteria	S	Competence protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SRR25158535_k127_783761_1	266940.Krad_3435	5.537e-40	158.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
SRR25158535_k127_783761_0	1120936.KB907211_gene27	9.942e-138	447.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4EFUG@85012|Streptosporangiales	201174|Actinobacteria	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SRR25158535_k127_785583_1	1380390.JIAT01000009_gene1598	2.526e-37	148.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4CTX9@84995|Rubrobacteria	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
SRR25158535_k127_785583_0	1206726.BAFV01000118_gene5813	7.779e-86	296.0	COG0500@1|root,COG0500@2|Bacteria,2I3GX@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158535_k127_785583_2	1957.JODX01000007_gene2278	1.402e-25	117.0	COG2519@1|root,COG2519@2|Bacteria,2GMKZ@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SRR25158535_k127_789627_3	1449976.KALB_7669	6.908e-55	202.0	COG0451@1|root,COG0451@2|Bacteria,2I8JF@201174|Actinobacteria,4E65N@85010|Pseudonocardiales	201174|Actinobacteria	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SRR25158535_k127_789627_0	1449976.KALB_7670	7.092e-134	432.0	COG1396@1|root,COG1396@2|Bacteria,2GKRR@201174|Actinobacteria,4E89B@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_789627_2	1968.JOEV01000009_gene1767	1.181e-96	352.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SRR25158535_k127_789627_1	882083.SacmaDRAFT_1320	2.262e-110	381.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4DYMX@85010|Pseudonocardiales	201174|Actinobacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SRR25158535_k127_79246_5	526225.Gobs_2398	1.81e-11	67.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EVDD@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_79246_0	675635.Psed_6299	4.354e-163	552.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4E1HN@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_79246_1	1283283.ATXA01000008_gene2989	7.741e-91	308.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
SRR25158535_k127_79246_2	1246995.AFR_23650	1.435e-19	93.0	COG0583@1|root,COG0583@2|Bacteria,2GNFT@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158535_k127_79246_3	1123024.AUII01000051_gene646	3.302e-19	96.0	2FKM2@1|root,34C81@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_79246_4	1429046.RR21198_2648	1.953e-14	73.0	COG3391@1|root,COG3391@2|Bacteria,2I9U0@201174|Actinobacteria,4FZI8@85025|Nocardiaceae	201174|Actinobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
SRR25158535_k127_793370_0	1122611.KB903985_gene3663	1.7e-105	364.0	COG2070@1|root,COG2070@2|Bacteria,2I93H@201174|Actinobacteria,4EIEF@85012|Streptosporangiales	201174|Actinobacteria	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
SRR25158535_k127_793370_2	391625.PPSIR1_22069	3.396e-50	190.0	COG0789@1|root,COG0789@2|Bacteria,1N1YK@1224|Proteobacteria	1224|Proteobacteria	K	Regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SRR25158535_k127_793370_1	443255.SCLAV_2580	1.038e-100	332.0	COG1609@1|root,COG1609@2|Bacteria,2GK7G@201174|Actinobacteria	201174|Actinobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
SRR25158535_k127_804085_1	1380347.JNII01000006_gene1628	1.982e-85	304.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
SRR25158535_k127_804085_0	497964.CfE428DRAFT_0631	4.186e-159	537.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
SRR25158535_k127_804085_2	243090.RB12326	1.993e-65	246.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SRR25158535_k127_804085_3	268407.PWYN_07095	1.36e-16	81.0	2EGSG@1|root,33AIJ@2|Bacteria,1VIME@1239|Firmicutes,4HQMI@91061|Bacilli,275D4@186822|Paenibacillaceae	91061|Bacilli	K	DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_808152_6	1463936.JOJI01000042_gene602	1.788e-29	119.0	COG2452@1|root,COG2452@2|Bacteria,2IDNQ@201174|Actinobacteria	201174|Actinobacteria	L	resolvase	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	Resolvase
SRR25158535_k127_808152_4	1463820.JOGW01000010_gene1078	1.72e-84	291.0	COG0675@1|root,COG0675@2|Bacteria,2GN1I@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_808152_0	1382356.JQMP01000003_gene1474	2.072e-121	405.0	COG1878@1|root,COG1878@2|Bacteria,2GBE2@200795|Chloroflexi,27Z29@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
SRR25158535_k127_808152_2	1160137.KB907310_gene4782	3.467e-98	332.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4FXY5@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA5	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SRR25158535_k127_808152_1	1121272.KB903253_gene6879	6.214e-120	396.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4DCEX@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SRR25158535_k127_808152_5	926550.CLDAP_31780	8.039e-82	282.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SRR25158535_k127_808152_8	926550.CLDAP_31340	2.227e-23	112.0	COG0392@1|root,COG0392@2|Bacteria,2G96U@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SRR25158535_k127_808152_7	391037.Sare_1088	2.828e-24	111.0	2F8ME@1|root,340ZZ@2|Bacteria,2IJJP@201174|Actinobacteria,4DDGU@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_808152_3	1254432.SCE1572_36735	4.795e-91	308.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,42RV4@68525|delta/epsilon subdivisions,2WP4W@28221|Deltaproteobacteria,2YVNU@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SRR25158535_k127_809857_0	47763.JNZA01000033_gene3075	1.803e-86	306.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
SRR25158535_k127_809857_1	1122138.AQUZ01000044_gene4501	8.457e-76	261.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4DQ35@85009|Propionibacteriales	201174|Actinobacteria	V	Transport permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
SRR25158535_k127_811926_14	1068980.ARVW01000001_gene6498	6.757e-32	131.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
SRR25158535_k127_811926_9	996637.SGM_3930	9.056e-48	180.0	COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria	201174|Actinobacteria	K	peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
SRR25158535_k127_811926_3	479434.Sthe_2181	1.837e-80	293.0	COG2041@1|root,COG2041@2|Bacteria,2G76Y@200795|Chloroflexi,27XUT@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
SRR25158535_k127_811926_4	1121926.AXWO01000025_gene3852	1.42e-70	249.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4EY0T@85014|Glycomycetales	201174|Actinobacteria	K	Sigma-70, region 4	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_811926_23	1463900.JOIX01000033_gene4257	2.125e-05	56.0	COG5662@1|root,COG5662@2|Bacteria,2IM2X@201174|Actinobacteria	201174|Actinobacteria	K	AntiSigma factor	rsrA	GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	-	-	-	-	-	-	-	-	-	zf-HC2
SRR25158535_k127_811926_7	351607.Acel_0566	4.059e-50	192.0	293MU@1|root,2ZR3M@2|Bacteria,2IFCB@201174|Actinobacteria,4ESJ1@85013|Frankiales	201174|Actinobacteria	Q	Superoxide dismutase	sodN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
SRR25158535_k127_811926_17	1229780.BN381_400037	2.383e-15	87.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,3UWRN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SRR25158535_k127_811926_6	1292020.H483_0110595	2.326e-52	197.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SRR25158535_k127_811926_19	446466.Cfla_2905	8.741e-12	69.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4F2SB@85016|Cellulomonadaceae	201174|Actinobacteria	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
SRR25158535_k127_811926_22	751945.Theos_0441	2.799e-06	57.0	2DMP7@1|root,32SU7@2|Bacteria,1WJU6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
SRR25158535_k127_811926_13	710111.FraQA3DRAFT_5620	4.873e-33	132.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4ET35@85013|Frankiales	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
SRR25158535_k127_811926_5	1283283.ATXA01000002_gene2800	1.238e-55	207.0	COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4ET26@85013|Frankiales	201174|Actinobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SRR25158535_k127_811926_1	298653.Franean1_0974	1.382e-102	346.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4ES7X@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SRR25158535_k127_811926_16	1245475.ANAE01000072_gene4829	2.913e-19	93.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria,4EJ0V@85012|Streptosporangiales	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SRR25158535_k127_811926_18	1944.JOAZ01000020_gene2826	1.243e-14	86.0	COG0500@1|root,COG2226@2|Bacteria,2IREW@201174|Actinobacteria,41CGH@629295|Streptomyces griseus group	201174|Actinobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SRR25158535_k127_811926_12	1123023.JIAI01000007_gene1983	3.218e-35	138.0	COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4E2M3@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	furB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SRR25158535_k127_811926_11	1869.MB27_05745	6.324e-38	158.0	COG1228@1|root,COG1228@2|Bacteria,2IISK@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
SRR25158535_k127_811926_0	525904.Tter_1206	4.069e-108	366.0	COG0215@1|root,COG0215@2|Bacteria,2NQRZ@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (C) catalytic domain	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905	DALR_2,tRNA-synt_1e,tRNA-synt_1g
SRR25158535_k127_811926_15	1122138.AQUZ01000001_gene1687	4.823e-25	114.0	2BZ6B@1|root,30N1Q@2|Bacteria,2I097@201174|Actinobacteria,4DWBN@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_811926_2	875328.JDM601_0685	1.501e-102	339.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,234Y8@1762|Mycobacteriaceae	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
SRR25158535_k127_811926_8	1123320.KB889683_gene2052	5.816e-49	186.0	COG2931@1|root,COG2931@2|Bacteria,2I3VG@201174|Actinobacteria	201174|Actinobacteria	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,DUF3455
SRR25158535_k127_811926_20	909613.UO65_5992	3.242e-08	60.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZ47@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD35	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
SRR25158535_k127_811926_10	1122609.AUGT01000024_gene360	9.273e-42	158.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Cupin_2
SRR25158535_k127_820443_2	1246995.AFR_40130	1.548e-08	68.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria,4DC7Q@85008|Micromonosporales	201174|Actinobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SRR25158535_k127_820443_0	351607.Acel_0284	1.44e-313	972.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4ERWB@85013|Frankiales	201174|Actinobacteria	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
SRR25158535_k127_820443_1	1146883.BLASA_3082	2.815e-27	125.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
SRR25158535_k127_820443_3	251221.35214569	2.278e-06	57.0	COG3631@1|root,COG3631@2|Bacteria,1G96H@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
SRR25158535_k127_822294_1	33876.JNXY01000039_gene6628	2.94e-66	228.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D9RE@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_822294_2	436229.JOEH01000027_gene2185	1.12e-60	215.0	COG1280@1|root,COG1280@2|Bacteria,2GMXB@201174|Actinobacteria,2NKN4@228398|Streptacidiphilus	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SRR25158535_k127_822294_4	1265310.CCBD010000070_gene47	1.68e-48	177.0	COG2315@1|root,COG2315@2|Bacteria,2II89@201174|Actinobacteria	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
SRR25158535_k127_822294_5	710111.FraQA3DRAFT_4467	1.36e-46	173.0	COG0346@1|root,COG0346@2|Bacteria,2IJAZ@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_822294_8	136993.KB900626_gene3452	3.609e-16	79.0	2CDW0@1|root,3313H@2|Bacteria,1NF68@1224|Proteobacteria,2UVS2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SRR25158535_k127_822294_3	298655.KI912266_gene6378	1.27e-52	192.0	COG3316@1|root,COG3316@2|Bacteria,2IS60@201174|Actinobacteria	201174|Actinobacteria	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
SRR25158535_k127_822294_9	1120949.KB903312_gene606	4.038e-10	68.0	COG3316@1|root,COG3316@2|Bacteria,2I5DA@201174|Actinobacteria,4DCQB@85008|Micromonosporales	201174|Actinobacteria	L	DDE domain	-	-	-	ko:K07498,ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
SRR25158535_k127_822294_10	1504672.669783726	0.0003026	49.0	COG5659@1|root,COG5659@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_822294_0	981369.JQMJ01000002_gene48	6.387e-170	546.0	COG5659@1|root,COG5659@2|Bacteria,2H7Y3@201174|Actinobacteria	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SRR25158535_k127_822294_7	1283283.ATXA01000023_gene251	1.976e-37	144.0	COG3576@1|root,COG3576@2|Bacteria,2I2W4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
SRR25158535_k127_82614_1	2002.JOEQ01000055_gene488	1.189e-69	242.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4ENGS@85012|Streptosporangiales	201174|Actinobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2,rve_3
SRR25158535_k127_82614_3	1214101.BN159_0118	2.72e-05	48.0	2DKWW@1|root,30NAT@2|Bacteria,2GKYJ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
SRR25158535_k127_82614_0	345341.KUTG_00319	1.847e-255	794.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4E23Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
SRR25158535_k127_82614_2	298653.Franean1_3065	5.062e-07	57.0	COG3415@1|root,COG3415@2|Bacteria,2I3BN@201174|Actinobacteria	201174|Actinobacteria	L	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
SRR25158535_k127_848681_2	1120950.KB892755_gene5958	2.379e-89	309.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4DREK@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07778	ko02020,map02020	M00479	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
SRR25158535_k127_848681_3	561175.KB894097_gene279	4.206e-63	229.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_848681_1	765420.OSCT_2525	1.005e-95	324.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	prk	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
SRR25158535_k127_848681_0	1229780.BN381_80377	6.772e-119	411.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
SRR25158535_k127_848681_4	1169154.KB897776_gene1898	2.855e-19	103.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SRR25158535_k127_874536_2	479433.Caci_4376	5.238e-16	85.0	2AN8T@1|root,327DN@2|Bacteria,2I81P@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
SRR25158535_k127_874536_0	525904.Tter_2661	5.074e-84	288.0	COG2365@1|root,COG2365@2|Bacteria,2NRBJ@2323|unclassified Bacteria	2|Bacteria	T	Tyrosine phosphatase family	iphP	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
SRR25158535_k127_874536_1	1229780.BN381_810007	3.958e-69	241.0	COG1948@1|root,COG1948@2|Bacteria,2HAMQ@201174|Actinobacteria	201174|Actinobacteria	L	ERCC4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ERCC4,Lsr2
SRR25158535_k127_890590_17	1313172.YM304_31100	1.064e-25	124.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
SRR25158535_k127_890590_13	469383.Cwoe_0398	2.314e-33	136.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
SRR25158535_k127_890590_19	1463853.JOHW01000004_gene2544	1.212e-16	89.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
SRR25158535_k127_890590_12	266117.Rxyl_0940	1.922e-33	140.0	COG1595@1|root,COG1595@2|Bacteria,2HG2Y@201174|Actinobacteria,4CTJS@84995|Rubrobacteria	84995|Rubrobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SRR25158535_k127_890590_6	1394178.AWOO02000048_gene6372	8.021e-52	201.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4ER4Y@85012|Streptosporangiales	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_890590_15	266117.Rxyl_2098	1.889e-29	134.0	COG0738@1|root,COG0738@2|Bacteria,2GRCY@201174|Actinobacteria,4CQ65@84995|Rubrobacteria	84995|Rubrobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_890590_18	469383.Cwoe_3470	1.844e-20	94.0	COG1225@1|root,COG1225@2|Bacteria,2I5Q2@201174|Actinobacteria,4CT3H@84995|Rubrobacteria	84995|Rubrobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
SRR25158535_k127_890590_2	1449080.JQMV01000003_gene580	1.398e-92	314.0	COG0863@1|root,COG0863@2|Bacteria,1WID5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA methylase	-	-	2.1.1.113,2.1.1.72	ko:K00590,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158535_k127_890590_0	525904.Tter_2590	5.427e-145	467.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SRR25158535_k127_890590_1	525904.Tter_2591	6.625e-104	354.0	COG0276@1|root,COG0276@2|Bacteria,2NQ0V@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Chloroa_b-bind,Ferrochelatase
SRR25158535_k127_890590_5	134676.ACPL_2414	2.435e-55	202.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4DENZ@85008|Micromonosporales	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_890590_9	1123320.KB889688_gene463	9.961e-38	159.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria	201174|Actinobacteria	KT	PspC domain protein	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
SRR25158535_k127_890590_4	1123024.AUII01000003_gene3587	5.505e-79	296.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4DXQC@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
SRR25158535_k127_890590_3	263358.VAB18032_00625	5.116e-88	308.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4D9AV@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_890590_7	471857.Svir_32220	6.206e-49	201.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4DXF7@85010|Pseudonocardiales	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
SRR25158535_k127_890590_8	1120949.KB903303_gene6809	4.686e-47	191.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DAB5@85008|Micromonosporales	201174|Actinobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
SRR25158535_k127_890590_14	525904.Tter_2095	2.417e-33	148.0	COG0642@1|root,COG2205@2|Bacteria,2NQXV@2323|unclassified Bacteria	2|Bacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA
SRR25158535_k127_890590_10	35754.JNYJ01000071_gene4249	6.332e-37	141.0	COG0675@1|root,COG0675@2|Bacteria,2GM6K@201174|Actinobacteria,4D8VQ@85008|Micromonosporales	201174|Actinobacteria	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
SRR25158535_k127_891957_0	1869.MB27_23030	8.871e-270	843.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SRR25158535_k127_891957_7	1206101.AZXC01000010_gene230	1.102e-10	65.0	2DRVB@1|root,33D80@2|Bacteria,2GRUJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_891957_3	469383.Cwoe_1524	1.829e-146	497.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158535_k127_891957_6	710686.Mycsm_03589	2.871e-14	76.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_891957_1	47839.CCAU010000005_gene481	1.039e-158	528.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,2366A@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
SRR25158535_k127_891957_4	477641.MODMU_2786	4.838e-56	200.0	COG4803@1|root,COG4803@2|Bacteria,2IFQ5@201174|Actinobacteria,4ET5T@85013|Frankiales	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_891957_5	479431.Namu_1736	8.692e-37	145.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4ETBE@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_891957_2	685727.REQ_18030	1.439e-148	475.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4FW4U@85025|Nocardiaceae	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SRR25158535_k127_892303_0	1000565.METUNv1_00935	4.606e-81	284.0	COG0469@1|root,COG2046@1|root,COG0469@2|Bacteria,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VR2T@28216|Betaproteobacteria,2KYGT@206389|Rhodocyclales	206389|Rhodocyclales	H	PUA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-sulfurylase,PK,PUA_2
SRR25158535_k127_892303_2	1048339.KB913029_gene4298	6.949e-53	188.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4ERNH@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SRR25158535_k127_892303_1	1120949.KB903295_gene2301	2.003e-56	202.0	COG1695@1|root,COG1695@2|Bacteria,2IH28@201174|Actinobacteria,4DI31@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
SRR25158535_k127_892303_4	298654.FraEuI1c_3934	1.907e-20	96.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SRR25158535_k127_892303_3	146922.JOFU01000012_gene1817	3.572e-23	104.0	COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SRR25158535_k127_894830_10	706587.Desti_4722	2.456e-51	199.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SRR25158535_k127_894830_7	1122622.ATWJ01000002_gene794	1.335e-74	274.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SRR25158535_k127_894830_15	1122622.ATWJ01000002_gene795	4.435e-31	127.0	COG1733@1|root,COG1733@2|Bacteria,2IRHS@201174|Actinobacteria,4FI6I@85021|Intrasporangiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
SRR25158535_k127_894830_5	1463881.KL591016_gene5400	3.589e-91	308.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria	201174|Actinobacteria	H	Dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SRR25158535_k127_894830_3	710696.Intca_0038	2.374e-123	408.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SRR25158535_k127_894830_18	1449355.JQNR01000005_gene2374	7.886e-15	81.0	2DRB9@1|root,33B2J@2|Bacteria,2GQE1@201174|Actinobacteria	201174|Actinobacteria	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
SRR25158535_k127_894830_0	1463856.JOHY01000006_gene40	0.0	1515.0	COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
SRR25158535_k127_894830_11	1120936.KB907227_gene2997	1.282e-45	174.0	COG1261@1|root,COG1261@2|Bacteria,2I6YM@201174|Actinobacteria,4ER8Y@85012|Streptosporangiales	201174|Actinobacteria	NO	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_894830_8	479433.Caci_8202	3.921e-72	263.0	COG5602@1|root,COG5602@2|Bacteria,2I4G1@201174|Actinobacteria	201174|Actinobacteria	B	Belongs to the OprB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_894830_2	2002.JOEQ01000004_gene3116	2.568e-216	692.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4EHJY@85012|Streptosporangiales	201174|Actinobacteria	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
SRR25158535_k127_894830_6	471852.Tcur_4141	8.184e-91	328.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria,4EHR0@85012|Streptosporangiales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158535_k127_894830_4	471852.Tcur_4140	6.967e-94	331.0	COG2064@1|root,COG2064@2|Bacteria,2HZTC@201174|Actinobacteria,4EH66@85012|Streptosporangiales	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
SRR25158535_k127_894830_22	58123.JOFJ01000019_gene3870	1.641e-07	62.0	2B1FJ@1|root,31TWB@2|Bacteria,2GT4D@201174|Actinobacteria,4EKFY@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_894830_16	1120936.KB907227_gene2991	5.273e-24	110.0	2E9PN@1|root,333W1@2|Bacteria,2GQYK@201174|Actinobacteria,4EJW5@85012|Streptosporangiales	201174|Actinobacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_894830_17	1120936.KB907227_gene2990	5.096e-23	111.0	COG4961@1|root,COG4961@2|Bacteria,2GRCJ@201174|Actinobacteria,4EJZJ@85012|Streptosporangiales	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
SRR25158535_k127_894830_19	561175.KB894093_gene3176	3.905e-13	81.0	2AQHK@1|root,31FQ6@2|Bacteria,2I1FE@201174|Actinobacteria,4EK4S@85012|Streptosporangiales	201174|Actinobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
SRR25158535_k127_894830_1	471852.Tcur_4135	5.975e-254	824.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria,4EHDB@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
SRR25158535_k127_894830_21	1192034.CAP_1403	6.569e-10	71.0	COG3209@1|root,COG3292@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3292@2|Bacteria,COG3391@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2YUH1@29|Myxococcales	28221|Deltaproteobacteria	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
SRR25158535_k127_894830_20	1288079.AUKN01000002_gene5482	4.491e-12	70.0	294XH@1|root,2ZSAG@2|Bacteria,2IQ7X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_894830_14	1454010.JEOE01000001_gene594	8.327e-35	146.0	2EJ40@1|root,33CVA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_894830_13	383372.Rcas_1535	6.635e-35	154.0	COG0500@1|root,COG2226@2|Bacteria,2G948@200795|Chloroflexi,376TJ@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_894830_12	266117.Rxyl_1312	8.686e-43	173.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SRR25158535_k127_895436_3	1160137.KB907308_gene6641	3.173e-16	92.0	COG1396@1|root,COG1396@2|Bacteria,2GR3F@201174|Actinobacteria,4G2H0@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix	clgR	GO:0002682,GO:0002683,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006109,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009268,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0010675,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031347,GO:0031348,GO:0032268,GO:0032502,GO:0033554,GO:0035821,GO:0040007,GO:0042176,GO:0043207,GO:0043565,GO:0043620,GO:0044003,GO:0044110,GO:0044111,GO:0044114,GO:0044115,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051252,GO:0051254,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0060255,GO:0061136,GO:0062012,GO:0065007,GO:0075136,GO:0080090,GO:0080134,GO:0085016,GO:0090062,GO:0097159,GO:1901363,GO:1902680,GO:1902882,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_31
SRR25158535_k127_895436_1	883113.HMPREF9708_00397	5.514e-50	188.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,27DPQ@186827|Aerococcaceae	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SRR25158535_k127_895436_2	525909.Afer_1824	2.792e-47	179.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,4CN92@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
SRR25158535_k127_895436_0	1828.JOKB01000013_gene3866	4.422e-189	616.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4G5PW@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
SRR25158535_k127_896403_0	1048339.KB913029_gene4046	2.732e-89	305.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4ES9C@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SRR25158535_k127_896403_2	656024.FsymDg_3277	4.303e-76	284.0	COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4ES7A@85013|Frankiales	201174|Actinobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SRR25158535_k127_896403_1	1313172.YM304_20800	2.829e-83	307.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CMYC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SRR25158535_k127_896403_3	710111.FraQA3DRAFT_6332	2.111e-08	66.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4ES3J@85013|Frankiales	201174|Actinobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SRR25158535_k127_8988_1	292459.STH1353	1.215e-54	211.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_8988_3	266940.Krad_4501	1.549e-32	146.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigM	GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SRR25158535_k127_8988_4	309801.trd_1542	1.464e-13	77.0	2DT3M@1|root,33IIP@2|Bacteria,2GA6N@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_8988_0	525904.Tter_1226	5.945e-130	423.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
SRR25158535_k127_8988_2	266940.Krad_4504	3.781e-35	147.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria	201174|Actinobacteria	O	belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SRR25158535_k127_899201_0	266117.Rxyl_2852	2.709e-86	297.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,4CQE1@84995|Rubrobacteria	84995|Rubrobacteria	I	6-phosphogluconate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
SRR25158535_k127_899201_1	1048339.KB913029_gene3800	9.693e-73	258.0	COG1225@1|root,COG1225@2|Bacteria,2II4M@201174|Actinobacteria	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SRR25158535_k127_899201_2	1283299.AUKG01000001_gene1430	7.506e-70	249.0	COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CRAC@84995|Rubrobacteria	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_900738_0	316274.Haur_2828	6.966e-240	750.0	COG0366@1|root,COG0366@2|Bacteria,2G86T@200795|Chloroflexi,377XJ@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SRR25158535_k127_900738_5	479432.Sros_5880	2.985e-39	160.0	2E5J0@1|root,330AB@2|Bacteria,2I805@201174|Actinobacteria,4ERAW@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_900738_3	1157640.AQWO01000004_gene4951	1.576e-59	213.0	COG1309@1|root,COG1309@2|Bacteria,2IIK3@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, tetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
SRR25158535_k127_900738_1	1313172.YM304_09930	7.966e-64	231.0	28TMF@1|root,2ZFV1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_900738_6	1027371.GOALK_086_00130	0.0002243	51.0	2EGCD@1|root,33A46@2|Bacteria,2I3NN@201174|Actinobacteria,4GDWB@85026|Gordoniaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SRR25158535_k127_900738_4	1380390.JIAT01000009_gene2129	1.807e-51	199.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria,4CRF2@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
SRR25158535_k127_900738_2	298654.FraEuI1c_2040	1.611e-60	222.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria	201174|Actinobacteria	S	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SRR25158535_k127_901344_2	1169154.KB897778_gene3265	9.725e-20	94.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08167	-	M00713,M00714	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.3	-	-	MFS_1
SRR25158535_k127_901344_1	103733.JNYO01000020_gene1878	2.824e-150	513.0	COG4191@1|root,COG4191@2|Bacteria,2GMRD@201174|Actinobacteria,4DXPK@85010|Pseudonocardiales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
SRR25158535_k127_901344_0	1068978.AMETH_4342	3.104e-260	811.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,2GK62@201174|Actinobacteria,4E11F@85010|Pseudonocardiales	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
SRR25158535_k127_902833_9	479432.Sros_8925	4.06e-30	124.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4EK6A@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
SRR25158535_k127_902833_6	1050202.KB913024_gene847	3.876e-38	156.0	COG0791@1|root,COG0791@2|Bacteria,2GIWB@201174|Actinobacteria,408UT@622450|Actinopolysporales	201174|Actinobacteria	M	NlpC/P60 family	-	GO:0005575,GO:0005576	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
SRR25158535_k127_902833_7	1120934.KB894414_gene3817	9.965e-32	143.0	COG0501@1|root,COG0501@2|Bacteria,2GTHQ@201174|Actinobacteria,4E8U9@85010|Pseudonocardiales	201174|Actinobacteria	O	Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
SRR25158535_k127_902833_4	35754.JNYJ01000035_gene3957	6.433e-48	188.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4DDEM@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	yqjI	-	-	-	-	-	-	-	-	-	-	-	PadR
SRR25158535_k127_902833_5	1050202.KB913024_gene1973	3.134e-41	157.0	2CCJS@1|root,32RVX@2|Bacteria,2IR2M@201174|Actinobacteria,4095T@622450|Actinopolysporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_902833_8	1298863.AUEP01000002_gene1582	1.372e-31	126.0	2BNAP@1|root,32GYA@2|Bacteria,2GTB3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_902833_0	469383.Cwoe_1524	4.063e-130	450.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
SRR25158535_k127_902833_3	1380390.JIAT01000011_gene2355	1.182e-53	193.0	COG4803@1|root,COG4803@2|Bacteria,2IIN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane protein of uknown function UCP014873	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_902833_10	67352.JODS01000015_gene7056	2.169e-24	110.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
SRR25158535_k127_902833_1	1380354.JIAN01000008_gene3319	8.155e-105	351.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_902833_2	219305.MCAG_04722	8.99e-60	218.0	COG1808@1|root,COG1808@2|Bacteria,2GJQ4@201174|Actinobacteria,4DA5U@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
SRR25158535_k127_904166_1	1283300.ATXB01000001_gene2240	1.03e-37	147.0	COG3415@1|root,COG3415@2|Bacteria,1QVAE@1224|Proteobacteria,1T533@1236|Gammaproteobacteria,1XGNF@135618|Methylococcales	135618|Methylococcales	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
SRR25158535_k127_904166_0	391616.OA238_c38840	6.854e-91	306.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
SRR25158535_k127_904166_2	395493.BegalDRAFT_2748	2.895e-18	91.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1R8BD@1224|Proteobacteria,1SKVJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
SRR25158535_k127_904466_2	1313172.YM304_04010	1.025e-34	133.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CN9T@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome b/b6/petB	-	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
SRR25158535_k127_904466_0	1229780.BN381_450010	5.838e-57	213.0	COG1290@1|root,COG1290@2|Bacteria,2H1Y8@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
SRR25158535_k127_904466_1	1229780.BN381_450009	8.284e-50	196.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
SRR25158535_k127_904466_3	1229780.BN381_450008	2.093e-13	83.0	COG2010@1|root,COG2010@2|Bacteria,2H49G@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SRR25158535_k127_906235_0	316274.Haur_3716	8.247e-105	358.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_906235_1	656024.FsymDg_4227	9.847e-100	334.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4EVZ6@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
SRR25158535_k127_907372_8	1464048.JNZS01000021_gene2712	4.392e-16	85.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4DCT4@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SRR25158535_k127_907372_4	465541.ATCJ01000005_gene6087	1.106e-64	228.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_907372_10	1122223.KB890697_gene1133	2.762e-12	78.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SRR25158535_k127_907372_12	525904.Tter_2787	0.0003633	50.0	2FDIX@1|root,345KC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_907372_6	479434.Sthe_3187	5.048e-40	153.0	COG3871@1|root,COG3871@2|Bacteria,2G9DN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SRR25158535_k127_907372_9	1042377.AFPJ01000050_gene1321	6.998e-15	81.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,1SAQE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YbaK prolyl-tRNA synthetase associated	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SRR25158535_k127_907372_0	196162.Noca_0658	7.503e-126	409.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4DPHZ@85009|Propionibacteriales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SRR25158535_k127_907372_5	710686.Mycsm_03934	7.937e-43	179.0	COG0454@1|root,COG0456@2|Bacteria,2I582@201174|Actinobacteria,23A4U@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SRR25158535_k127_907372_1	358823.DF19_15670	2.934e-114	374.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
SRR25158535_k127_907372_11	1463879.JOHP01000001_gene1484	3.577e-11	64.0	COG3653@1|root,COG3653@2|Bacteria,2I8X9@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
SRR25158535_k127_907372_2	1194165.CAJF01000003_gene2660	1.326e-97	331.0	COG0258@1|root,COG0258@2|Bacteria,2GKTZ@201174|Actinobacteria,4FN39@85023|Microbacteriaceae	201174|Actinobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	polA_1	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
SRR25158535_k127_907372_3	1120949.KB903317_gene1732	2.43e-88	294.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DA13@85008|Micromonosporales	2|Bacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
SRR25158535_k127_910067_0	419947.MRA_2763	0.0	1021.0	COG0468@1|root,COG1372@1|root,COG0468@2|Bacteria,COG1372@2|Bacteria,2GJ4P@201174|Actinobacteria,232KV@1762|Mycobacteriaceae	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SRR25158535_k127_910067_5	1283283.ATXA01000001_gene1051	5.568e-11	74.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4ETC2@85013|Frankiales	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
SRR25158535_k127_910067_1	1122611.KB903948_gene6671	1.978e-178	576.0	COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4EG5E@85012|Streptosporangiales	201174|Actinobacteria	V	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
SRR25158535_k127_910067_2	479431.Namu_3986	1.605e-167	539.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4ERFI@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SRR25158535_k127_910067_4	1122138.AQUZ01000025_gene2760	4.934e-37	149.0	COG3885@1|root,COG3885@2|Bacteria,2GN3T@201174|Actinobacteria,4DRGI@85009|Propionibacteriales	201174|Actinobacteria	S	ferrous iron binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_910067_3	909613.UO65_6422	1.281e-70	274.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4DX5R@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
SRR25158535_k127_919120_1	485913.Krac_1259	3.03e-111	372.0	COG3293@1|root,COG3293@2|Bacteria,2G9EK@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
SRR25158535_k127_919120_0	1382306.JNIM01000001_gene1548	6.736e-129	444.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_923728_0	266117.Rxyl_2428	2.026e-185	597.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SRR25158535_k127_923728_4	1385520.N802_13815	3.608e-19	94.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4FGBX@85021|Intrasporangiaceae	201174|Actinobacteria	T	DNA-binding protein	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SRR25158535_k127_923728_2	656024.FsymDg_3065	1.572e-28	134.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4ET0T@85013|Frankiales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SRR25158535_k127_923728_1	1380390.JIAT01000010_gene4530	2.783e-74	271.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CQ1Y@84995|Rubrobacteria	84995|Rubrobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SRR25158535_k127_923728_3	644283.Micau_2273	6.986e-21	92.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4DA63@85008|Micromonosporales	201174|Actinobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SRR25158535_k127_923805_3	1179773.BN6_33300	8.71e-14	75.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria,4E98F@85010|Pseudonocardiales	201174|Actinobacteria	L	Transposase DDE domain	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158535_k127_923805_0	653045.Strvi_4608	4.341e-140	462.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
SRR25158535_k127_923805_1	665577.JH993790_gene5869	1.643e-105	352.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
SRR25158535_k127_923805_2	867903.ThesuDRAFT_01292	6.11e-29	119.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SRR25158535_k127_925786_6	1894.JOER01000009_gene8027	1.021e-46	171.0	COG1005@1|root,COG1005@2|Bacteria,2GN3R@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH2	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SRR25158535_k127_925786_4	1116232.AHBF01000045_gene2363	1.996e-72	263.0	COG1143@1|root,COG1143@2|Bacteria,2GPSS@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI2	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SRR25158535_k127_925786_8	58123.JOFJ01000002_gene2674	3.321e-34	139.0	COG0839@1|root,COG0839@2|Bacteria,2GJB7@201174|Actinobacteria,4EIJM@85012|Streptosporangiales	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ2	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SRR25158535_k127_925786_9	1120950.KB892779_gene933	3.237e-32	128.0	COG0713@1|root,COG0713@2|Bacteria,2IHNW@201174|Actinobacteria,4DVKP@85009|Propionibacteriales	201174|Actinobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	nuoK2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SRR25158535_k127_925786_1	717605.Theco_3848	4.209e-148	491.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,26SE0@186822|Paenibacillaceae	91061|Bacilli	CP	Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SRR25158535_k127_925786_0	1122611.KB904001_gene8116	2.449e-158	514.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,4EI1F@85012|Streptosporangiales	201174|Actinobacteria	C	Proton-conducting membrane transporter	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158535_k127_925786_2	1313172.YM304_35550	4.754e-107	364.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,4CMT6@84992|Acidimicrobiia	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SRR25158535_k127_925786_10	419947.MRA_1572	1.105e-17	84.0	COG5450@1|root,COG5450@2|Bacteria,2GTYZ@201174|Actinobacteria,23BQF@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	GO:0006417,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040008,GO:0043207,GO:0044403,GO:0044419,GO:0045727,GO:0045927,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:2000112	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SRR25158535_k127_925786_7	1123024.AUII01000064_gene4	1.148e-35	140.0	COG1487@1|root,COG1487@2|Bacteria,2ISE2@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
SRR25158535_k127_925786_3	1120950.KB892748_gene3207	3.134e-76	277.0	COG1668@1|root,COG1668@2|Bacteria,2I9MY@201174|Actinobacteria,4DQIN@85009|Propionibacteriales	201174|Actinobacteria	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SRR25158535_k127_925786_5	479433.Caci_6164	1.508e-56	201.0	COG4152@1|root,COG4152@2|Bacteria,2I2DK@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SRR25158535_k127_925883_3	1122611.KB903961_gene4392	1.897e-41	156.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4EHXK@85012|Streptosporangiales	201174|Actinobacteria	S	Peptidase dimerisation domain	amiA	-	-	ko:K01436,ko:K06048	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SRR25158535_k127_925883_0	1211815.CBYP010000045_gene795	4.905e-168	537.0	COG2170@1|root,COG2170@2|Bacteria,2GKAA@201174|Actinobacteria,4ES1F@85013|Frankiales	201174|Actinobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
SRR25158535_k127_925883_2	258533.BN977_00324	4.587e-52	188.0	28M3Q@1|root,2ZAHT@2|Bacteria,2GM5B@201174|Actinobacteria,23476@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_925883_1	67315.JOBD01000013_gene6972	1.605e-119	401.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
SRR25158535_k127_925883_6	300852.55771486	2.08e-20	94.0	COG0662@1|root,COG0662@2|Bacteria,1WK83@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SRR25158535_k127_925883_5	1127134.NOCYR_4126	7.224e-34	143.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,4FVR0@85025|Nocardiaceae	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
SRR25158535_k127_925883_7	345341.KUTG_01764	1.009e-09	70.0	COG0508@1|root,COG0508@2|Bacteria,2GQQK@201174|Actinobacteria,4EFB2@85010|Pseudonocardiales	201174|Actinobacteria	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_925883_4	246196.MSMEI_2065	2.156e-36	141.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,23549@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_925971_0	1961.JOAK01000003_gene1742	4.522e-186	590.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
SRR25158535_k127_925971_4	105420.BBPO01000065_gene3992	3.92e-12	75.0	COG5421@1|root,COG5421@2|Bacteria,2GK2A@201174|Actinobacteria,2NJVN@228398|Streptacidiphilus	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_925971_3	105420.BBPO01000065_gene3992	1.94e-13	82.0	COG5421@1|root,COG5421@2|Bacteria,2GK2A@201174|Actinobacteria,2NJVN@228398|Streptacidiphilus	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SRR25158535_k127_925971_1	469383.Cwoe_4981	6.34e-37	146.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SRR25158535_k127_925971_2	1380390.JIAT01000013_gene110	4.654e-22	109.0	COG1309@1|root,COG1309@2|Bacteria,2HAUK@201174|Actinobacteria,4CRDY@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SRR25158535_k127_932540_2	298655.KI912267_gene6800	5.248e-13	69.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SRR25158535_k127_932540_1	696281.Desru_2304	4.503e-27	126.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
SRR25158535_k127_932540_0	469383.Cwoe_1176	5.755e-45	177.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CQ0G@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SRR25158535_k127_950673_0	502025.Hoch_2100	0.0	1933.0	COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,1P6RE@1224|Proteobacteria,43A2M@68525|delta/epsilon subdivisions,2X1XW@28221|Deltaproteobacteria,2YX2T@29|Myxococcales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase, central region	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
SRR25158535_k127_950673_1	204669.Acid345_0465	1.152e-153	497.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria,2JHJH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
SRR25158535_k127_952321_8	1123013.AUIC01000004_gene1811	1.078e-26	115.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4FKFP@85023|Microbacteriaceae	201174|Actinobacteria	L	RecG wedge domain	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon
SRR25158535_k127_952321_9	44060.JODL01000009_gene1834	2.082e-22	98.0	COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SRR25158535_k127_952321_5	263358.VAB18032_10245	1.016e-58	207.0	COG0748@1|root,COG0748@2|Bacteria,2I3CW@201174|Actinobacteria,4DEAN@85008|Micromonosporales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
SRR25158535_k127_952321_4	1146883.BLASA_4654	2.311e-69	251.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria,4ESP8@85013|Frankiales	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K20469	-	-	-	-	ko00000,ko02000	2.A.86.1.7	-	-	AI-2E_transport
SRR25158535_k127_952321_10	1382306.JNIM01000001_gene1395	2.008e-19	97.0	2CKD9@1|root,333BQ@2|Bacteria,2G7BT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_952321_12	266117.Rxyl_2554	2.038e-13	76.0	COG1051@1|root,COG1051@2|Bacteria,2GZ4B@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the NUDIX hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SRR25158535_k127_952321_3	43759.JNWK01000023_gene5236	1.965e-82	303.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SRR25158535_k127_952321_0	909613.UO65_4137	2.674e-182	591.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4DXSX@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
SRR25158535_k127_952321_1	926560.KE387027_gene536	4.659e-128	427.0	COG1231@1|root,COG1231@2|Bacteria,1WJ0T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SRR25158535_k127_952321_6	1123024.AUII01000001_gene2735	1.219e-58	216.0	COG0611@1|root,COG0611@2|Bacteria,2GP6E@201174|Actinobacteria,4DY1U@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0008150,GO:0040007	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c	AIRS,AIRS_C
SRR25158535_k127_952321_2	391625.PPSIR1_25986	1.979e-85	314.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169,iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560	PEPCK_ATP
SRR25158535_k127_952321_7	477974.Daud_2224	9.762e-48	180.0	COG1926@1|root,COG1926@2|Bacteria,1V256@1239|Firmicutes,249BZ@186801|Clostridia,2623X@186807|Peptococcaceae	186801|Clostridia	F	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SRR25158535_k127_952321_11	1283287.KB822576_gene3968	1.809e-14	76.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4DRPI@85009|Propionibacteriales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SRR25158535_k127_9621_2	66377.JOBH01000008_gene6570	1.184e-73	266.0	COG0477@1|root,COG0477@2|Bacteria,2IIAH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,Sugar_tr
SRR25158535_k127_9621_1	1122138.AQUZ01000030_gene4646	1.227e-75	270.0	COG0583@1|root,COG0583@2|Bacteria,2GJFG@201174|Actinobacteria,4DW8J@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SRR25158535_k127_9621_3	1440053.JOEI01000002_gene3544	0.0004837	53.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
SRR25158535_k127_9621_0	1968.JOEV01000003_gene3298	5.848e-78	272.0	COG1735@1|root,COG1735@2|Bacteria,2GMZ6@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
SRR25158535_k127_991166_1	512565.AMIS_62100	5.294e-31	125.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4DE0A@85008|Micromonosporales	201174|Actinobacteria	J	integration host factor	mihF	-	-	-	-	-	-	-	-	-	-	-	-
SRR25158535_k127_991166_0	760568.Desku_1292	1.202e-42	169.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,261GR@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SRR25158535_k127_991166_2	794903.OPIT5_26150	1.355e-06	54.0	COG0284@1|root,COG0284@2|Bacteria,46T17@74201|Verrucomicrobia,3K7VT@414999|Opitutae	414999|Opitutae	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
## 3823 queries scanned
## Total time (seconds): 5.391510486602783
## Rate: 709.08 q/s